Protein (view, download) , Domain (view, download)
KSR2_Hsap       MDEENMTKSEEQ-----------------QPLSLQKAL-QQCELVQNMIDLSISNLEGLR
KSR1_Hsap       MDRAALRAAAMGEKKEGGGGGDAAAAEGGAGAAASRAL-QQCGQLQKLIDISIGSLRGLR
ksr-1_Cele      MMQTQVASRAGY---------------SNLP----Q--F-GAGIAQDIKTQAINNLKECL
KSR1_Spur       LLMEKVQ-----------------------------------------------------
KSR2_Spur       MQPKEHIALIM--------------EQLQK------------------------------
KSR1_Mmus       MDRAALRAAAMGEKKEGGGGG--AAADGGAGAAVSRAL-QQCGQLQKLIDISIGSLRGLR
KSR2_Mmus       MDEENMTKSEEQ-----------------QPLSLQKAL-QQCELVQNMIDLSISNLEGLR
ksr_Dmel        MSSNNNAPASAPDT----GST-----NANDPISGSLSVDSNLVIIQDMIDLSANHLEGLR
AqueK675_Aque   MSTRRDILSL--------------------------------------------------
AqueK676_Aque   MSATTATAVYSSSI----GQ---TQDDKKDLFSVTK--G-KMKVQQRMIDLTARELESTR
                :

KSR2_Hsap       TKCA-----TSNDLT---QKEIRTLESKLVKYFSRQLSCKKKVALQE-------------
KSR1_Hsap       TKCA-----VSNDLT---QQEIRTLEAKLVRYICKQRQCKLSVAPGE-------------
ksr-1_Cele      KLTT-----INRFLTSSYEEDAKSVERKIFSAVY---QMTK-IGLID-------------
KSR1_Spur       ------------------------------------------------------------
KSR2_Spur       ------------------------------------------------------------
KSR1_Mmus       TKCS-----VSNDLT---QQEIRTLEAKLVKYICKQQQSKLSVTPSD-------------
KSR2_Mmus       TKCA-----ASNDLT---QKEIRTLESKLVKYFSRQLSCKKKVALQE-------------
ksr_Dmel        TQCA-----ISSTLT---QQEIRCLESKLVRYFSELLLAKMR--LNE-------------
AqueK675_Aque   --------------------------------LH---HQQK-------------------
AqueK676_Aque   VSSQSIPSDGSSDAL---KENIVLVENKLMKLFSRQLMHKH-ICLKELINAGGVSHFDFE


KSR2_Hsap       -RNAEL-----DGFPQLRHWFRIVDVRKEVLEEIS--PGQLSLEDLLEMTDEQVCETVEK
KSR1_Hsap       -RTPEL-----NSYPRFSDWLYTFNVRPEVVQEI---PRDLTLDALLEMNEAKVKETLRR
ksr-1_Cele      REKREI-----NA-----IWFTFVGLSAQNIRHLEI-CSITDFNALFSITNQELRSLADR
KSR1_Spur       -----------------------------------------NLSHLIKHGESEIRTIMKI
KSR2_Spur       ------------------------------------------------------------
KSR1_Mmus       -RTAEL-----NSYPRFSDWLYIFNVRPEVVQEI---PQELTLDALLEMDEAKAKEMLRR
KSR2_Mmus       -RNAEL-----DGFPQLRHWFRIVDVRKEVLEEIS--PDQLSLEDLLEMTDEQVCETVEK
ksr_Dmel        -RIPANGLVPHTTGNELRQWLRVVGLSQGTLTACL--ARLTTLEQSLRLSDEEIRQLLAD
AqueK675_Aque   ------------------------------------------------------------
AqueK676_Aque   QTNDEL-----DSLISFKMFLTVTGLEELSVKSLSSEKEKLSVDRLFQMTPQELQYLFSR


KSR2_Hsap       YGAN--REECARLNASLSCLRNVHMS--GGNLS-KQ-DWTIQWPTTETG-----------
KSR1_Hsap       CGAS--GDECGRLQYALTCLRKVTGL--GGEH--KE-D--SSWSSLDARRESGSGPSTDT
ksr-1_Cele      GRLD--VETKRKLLQSTVILQNHWNA----------------------------------
KSR1_Spur       CGCE--EKEITRLLDAVKNLKKTFNA--NYP--SKDRSLEDGAKSPDAV---SMGNSIET
KSR2_Spur       ------------------------------------------------------------
KSR1_Mmus       WGAS--TEECSRLQQALTCLRKVTGL--GGEH--KM-D--SGWSSTDARDS-SLGPPMDM
KSR2_Mmus       YGAN--QEECARLNASLSCLRNVHKS--GGNLS-KQ-DWIIQWPTTEPG-----------
ksr_Dmel        SPSQREEEELRRLTRAMQNLRKCMESLESGTAASNNDPEQWHWDSWDRPTHIHRGSV--G
AqueK675_Aque   ------------------------------------------------------------
AqueK676_Aque   LEIT--ARDCHKLVSLLDLMSLYYEKWE---KG--EN---PPPGLYDVRRNSSSGR-LNS


KSR2_Hsap       ----------KENNPVCPPEPTPWIRT-HLSQSPRVPSKCVQHYCHTSPTPGAPVYTHVD
KSR1_Hsap       L---------SAASLPWPPGSSQLGRAGNSAQGPRS------------------------
ksr-1_Cele      ---YHSR---T----------S----SG-STDEPSG------------------------
KSR1_Spur       V----------------------IDLSRSRSNSPS-------------------------
KSR2_Spur       ------------------------------------------------------------
KSR1_Mmus       L--------------------SSLGRAGASTQGPRS------------------------
KSR2_Mmus       ----------QESNPVCPPEPSPWIRT-HLSQSPRVQTKCPQHFCPTSPTPGTPVYTQVD
ksr_Dmel        N----------------------IGLGNNSTASPRTHHRQ--HGVK-----GKN-----S
AqueK675_Aque   ----------T---------------RGTDQSSPVN------------------------
AqueK676_Aque   LTSLESRKDSTSSHTISPPAGN----HGSRSSTPLT------------------------


KSR2_Hsap       RLTVDAYPGLCPP-P--PLESGHRSLPPSPRQRHAVRTPPRTPN----------------
KSR1_Hsap       -ISVSALPASDSPTP--SFSEGL-SDTCIPLHA-SGRLTPRAL-----------------
ksr-1_Cele      ----QSTPAIVTPSP--KF-----NVPSLSV-T-SA----------------------KM
KSR1_Spur       ---VSSSP--EQKRP--S-IDSL-SSDLS-EVP-SVPITPPPFN-------------NKI
KSR2_Spur       ------------------------------------------------------------
KSR1_Mmus       -ISVSALPASDSPVP--GLSEGL-SDSCIPLHT-SGRLTPRAL-----------------
KSR2_Mmus       RLTVDAYPNLCPPPP--PLESGHRSLPPSPRQRHVVRTPPRTPN----------------
ksr_Dmel        ALANSTNFKSGRQSP--SATEEL-NSTQG-SQL-TLTLTPSPPN-------------S--
AqueK675_Aque   ----VAVPSITVSSP--RS-----------R-S-NS----------------------RN
AqueK676_Aque   ----PLTPSST-QSPFQGLVHQN-STPSIPTHS-VPYDNIRSTSSCGCGGHALSESSGQH


KSR2_Hsap       -------------------------------IVT-T-VTPP--------GTPPMRKKNKL
KSR1_Hsap       --------------------------------HS-F-ITPP--------TTPQLRRHTKL
ksr-1_Cele      IQS---------------------------SSMG-F-ATTP--------KSP--------
KSR1_Spur       --F---------------------------KLPP-M-PTPP--------HTPTFNKRVK-
KSR2_Spur       ------------------------------------------------------------
KSR1_Mmus       --------------------------------HS-F-ITPP--------TTPQLRRHAKL
KSR2_Mmus       -------------------------------IVT-T-VTPP--------GTPPMRRKNKL
ksr_Dmel        -----------------------------------P-FTPSSGLSSSLNGTPQ---RSR-
AqueK675_Aque   AVI---------------------------GGNG-Y-PQPP--------ASP--------
AqueK676_Aque   LSSSMSSLGSDLGLHVAHSNETTHLPTASNQSHDVYQTTPP--------APPTYSSSLRA


KSR2_Hsap       K----PP--GTPPPSSRKLIHLIPG--------------------FTALHRSKSH-EFQL
KSR1_Hsap       K----PP--RTPPPPSRKVFQLLPS--------------------FPTLTRSKSH-ESQL
ksr-1_Cele      ------------------------------------------------------------
KSR1_Spur       ---------GKTPPLTRKTNLPLPA--------------------QSNWNSD-NHLNKRS
KSR2_Spur       ------------------------------------------------------------
KSR1_Mmus       K----PP--RTPPPPSRKVFQLLPS--------------------FPTLTRSKSH-ESQL
KSR2_Mmus       K----PP--GTPPPSSRKLIHLIPG--------------------FTALHRSKSH-EFQL
ksr_Dmel        ---------G-TPPPARKHQTLLSQ----------------------------SH-VQ--
AqueK675_Aque   ------------------------------------------------------------
AqueK676_Aque   KKKIGHTRSHSNPPLAN---LIMPEAVPENSVPEYRSPSPPYYNGHAPPTRTGSH-PSII


KSR2_Hsap       GHRVDEAHTPKA-KK--KSKPL--------------------------NLKIHSSVGSCE
KSR1_Hsap       GNRIDDVSS---------------------------------------------------
ksr-1_Cele      ------------------------------------------------------------
KSR1_Spur       GPGYDSATLGRI-QV--RSRDQ--------------------------HTRRYSDDQSVM
KSR2_Spur       ------------------------------------------------------------
KSR1_Mmus       GNRIDDVTP---------------------------------------------------
KSR2_Mmus       GNRVDEANTPKA-KK--KSKPL--------------------------NLKIHSGVGSCE
ksr_Dmel        ---VDGEQLARN-RL--PTD----------------------------------------
AqueK675_Aque   ------------------------------------------------------------
AqueK676_Aque   HNSIANSNQSLANSTSTKSHPQVRRLMAGNYNFSRSISTDLGDVQPDPPLRSNSEASSVQ


KSR2_Hsap       N--------------------IPSQQRSPLLSERSLRSFFVGHAPFLPSTPPVH-TEANF
KSR1_Hsap       ------------------------------------------------------------
ksr-1_Cele      ------------------------------------------------------------
KSR1_Spur       ------------------------RLSSPCRSEERLTDIGVP--------PK--------
KSR2_Spur       ------------------------------------------------------------
KSR1_Mmus       ------------------------------------------------------------
KSR2_Mmus       N--------------------IPAQQRSPLLSERSLRSFFVGHGPFLPSTPPVH-TEANF
ksr_Dmel        --------------------------PSPDSHSSTSSDIFVD--------PNTNASSGGS
AqueK675_Aque   ------------------------------------------------------------
AqueK676_Aque   SASPRQRRLSKEVGTSTSMVDLPLIQCSVEQSEFPSSSVKSHSVPRLAN-LTINTTTG--


KSR2_Hsap       SANTLSVPRWSPQIPR-----RDLGNSIKHRFSTK---YWM-SQTCTVCGKGML----F-
KSR1_Hsap       --MRFDLSHGSPQMVR-----RDIGLSVTHRFSTK---SWL-SQVCHVCQKSMI----F-
ksr-1_Cele      ------------KTSS-----R-LVHAIPHKWHRSTKFRFSGDAVCHFCQRPLGFGFLNA
KSR1_Spur       -QGKL-VPPKSPRATH----RSNMIHAIKHRFSKK---TSMKPQSCDYCHEKIVI---LQ
KSR2_Spur       ----------------------TLLLRAKHCYTRQ---LVSPAKRCDFCKKSMFV----M
KSR1_Mmus       --MKFELPHGSPQLVR-----RDIGLSVTHRFSTK---SWL-SQVCNVCQKSMI----F-
KSR2_Mmus       SANTLSVPRWSPQIPR-----RDLGNSIKHRFSTK---YWM-SQTCTVCGKGML----F-
ksr_Dmel        SSNVL-MVPCSPGVGH-----VGMGHAIKHRFTKA---LGF-MATCTLCQKQVF----HR
AqueK675_Aque   -----------------------LLHWSTG------------------------------
AqueK676_Aque   DHNSTSVP-TSPRIPTNYNPTGVMGHKIDHRFINH---IFFGVQECDYCKKSMVV----S
                                       :

KSR2_Hsap       GLKCKNCKLKCHNKCTKEA---PPCHLLIIHRGDPARLVRT-------------------
KSR1_Hsap       GVKCKHCRLKCHNKCTKEA---PACRISFLP---LTRLRRT-------------------
ksr-1_Cele      WEKCRSCKWKVHTQCKGRV--GDSCGLTPDHL-RFLF-D------------------KLI
KSR1_Spur       RYKCKDCKYICHSNCKFHAEKVPSCGLPRKYE-EIFRETIN-------------------
KSR2_Spur       TLRCKDCRVRCHRRCAQQA--ANLCELAAKHNLTTGPESRNVVPTCHAALAEASRRHQSA
KSR1_Mmus       GVKCKHCRLKCHNKCTKEA---PACRITFLP---LARLRRT-------------------
KSR2_Mmus       GLKCKNCKLKCHNKCTKEA---PPCHLLIIHRGDPARLVRT-------------------
ksr_Dmel        WMKCTDCKYICHKSCAPHV--PPSCGLPREYV-DEFRHIKE-------------------
AqueK675_Aque   ------------------------------------------------------------
AqueK676_Aque   GYRCRYCKSKFHKNCSKLA--PPICGLPKYFL-NYARQHFMMSP-SHESVYQVNKTGHLT


KSR2_Hsap       ---ESVPCDINNPLRKPPR---------YSDLHISQTL-PKT---------NKINKD---
KSR1_Hsap       ---ESVPSDINNPVDR------------AAEPHF-GTL-PKA---------L-TKKE---
ksr-1_Cele      QE-N------NGGM--------------WKDP---QSV-PGS----------R--SM---
KSR1_Spur       ---SA-------------R---------TDPPTV------------------------VN
KSR2_Spur       NS-TPVPTHRRKSSTESFRE---------IETHQ-STFSVRRSTTRQRLSTTTVPKD---
KSR1_Mmus       ---ESVPSDINNPVDR------------AAEPHF-GTL-PKA---------L-TKKE---
KSR2_Mmus       ---ESVPCDINNPVRKPAR---------YSDLHISQTL-PKT---------NKINKD---
ksr_Dmel        ---QGG------------Y---------ASLPHVHGAA-KGS---------PLVKKSTLG
AqueK675_Aque   ---------------------------------------RR-------------------
AqueK676_Aque   SSGEYGSCNTPTPSSEQLREETFFIHDLNREPSK-NQFSPVT----------STKRP---


KSR2_Hsap       HIPVPY----QPDSSSNP-S----------------------------------------
KSR1_Hsap       HPPAMN----HLDSSSNP-S----------------------------------------
ksr-1_Cele      NEPAFQ----FPDTAIDSSS----------------------------------------
KSR1_Spur       --VASS----TGDSSSNP-S----------------------------------------
KSR2_Spur       HSLGRVSRSTLSSQSSNRSSVSGYYSQESDASLLSECDTPKEI-----------SVFDSF
KSR1_Mmus       HPPAM-----NLDSSSNP-S----------------------------------------
KSR2_Mmus       HIPVPY----QPDSSSNP-S----------------------------------------
ksr_Dmel        KPLHQQ----HGDSSSPS-S----------------------------------------
AqueK675_Aque   --VWS-----EPGGSSGLS-----------------------------------------
AqueK676_Aque   HPPAPS----SPAHDHAPFSSSHS-TSRLEVPQL--------FLPGVRSHSNYRHPHHHR


KSR2_Hsap       ---STTSSTPSSPAP---P--LP------PSATP--PSP-LHPSPQCTRQ-QKNFNLPAS
KSR1_Hsap       ---STTSSTPSSPAP---F--P-------TSSNP--SSATTPPNPSPGQR-DSRFNFPAA
ksr-1_Cele      ---STNSSAPSTPAL---P--AG------ISGNV--SSL-TAPY----R-SERKFLFPDT
KSR1_Spur       ---STTSSTPSSPAP---F--IS------TSGIPLPSPSPALPSPSPRMM-VPQFKFPPD
KSR2_Spur       GPGDVTSPIPSSSRSRRHEAWA---------ATK--PAP-TSTY----M-D-------CP
KSR1_Mmus       ---STTSSTPSSPAP---F--L-------TSSNP--SSATTPPNPSPGQR-DSRFSFPAA
KSR2_Mmus       ---STTSSTPSSPAP---P--LP------PSATP--PSP-LHPSPQCPRQ-KKNFNLPAS
ksr_Dmel        ---SCTSSTPSSPAL---F--QQRERELDQAGSS--SSANLLPTPSLGKHQPSQFNFPNV
AqueK675_Aque   ---ASS---------------LL------VDSGR--SSL-TS-Y----G-SQESLLFTS-
AqueK676_Aque   VPPHSTSSSPSTSSQ---SSPCL------TPMSP--RSP-LDPP----V-E-------YS
                     .                               .

KSR2_Hsap       HY--YKYK-------------QQ-FIF-PD------------------------------
KSR1_Hsap       YF--IHHR-------------QQ-FIF-PV-----------PSAGHCWKCL--------L
ksr-1_Cele      ENYSVHNR-------------LP-IL-------------VISEGDHPTTTE--------I
KSR1_Spur       VS--DDV--------------SE-------------------------------------
KSR2_Spur       ------------------------------------------------AHGNCESGAETN
KSR1_Mmus       YF--IHHR-------------QQ-FIF-PD------------------------------
KSR2_Mmus       HY--YKYK-------------QQ-FIF-PD------------------------------
ksr_Dmel        TV--TSSGGSGGVSLISNEPVPEQFPTAPATANGGLDSLVSSSNGHM-SS----------
AqueK675_Aque   ------------------------------------------------------------
AqueK676_Aque   GFNSL-HR-------------SI-AI-------------VLSTDDNTSSTDEEGDGP---


KSR2_Hsap       -----------VVPVPETPTRA------------------------------PQVIL---
KSR1_Hsap       IAESLKENAFNISAFAHA---A------------------------------P---L---
ksr-1_Cele      QQETENH------NKSAAA-----------------------------------------
KSR1_Spur       ---FLDN---N-----------------------------------------ENV-T---
KSR2_Spur       LMMSLDGG-S--LVATWPQ-----------------------------------------
KSR1_Mmus       -----------ISACSQA---A------------------------------P---L---
KSR2_Mmus       -----------VVPVPETPTRA------------------------------PQVIL---
ksr_Dmel        ---LIGS---QTSNASTAATLTG-----------------------------SLV-N---
AqueK675_Aque   ------------------------------------------------------------
AqueK676_Aque   DGEFYEGS-E--GFTSDSS---NSSFNEVGLVGPAHNRGLKLPSRGIAAQSLPNLLMAER


KSR2_Hsap       -----------------------------HPVTSNPI-----------LEG--N--PLLQ
KSR1_Hsap       -----------------------------PEAADGTR-----------LDD--Q--PKAD
ksr-1_Cele      -----------------------------S--MSGNI------------ESE-GT-----
KSR1_Spur       -----------------------------STSSDRT--------------------ITVD
KSR2_Spur       -------------------------DRKCN--C----------------------CPHI-
KSR1_Mmus       -----------------------------SSTADSTR-----------LDD--Q--PKTD
KSR2_Mmus       -----------------------------HPVTSNTI-----------LEG--N--PLLQ
ksr_Dmel        -----------------------------STTTTSTCSFFPRKLSTAGVDKR-TP-FTSE
AqueK675_Aque   ------------------------------------------------------P-----
AqueK676_Aque   RQSRGGGANGEGLYATSEDNLQSWYDRKPS--LSGTI---STA------DSKTSTLVGS-


KSR2_Hsap       I--E-VEP-TSENEEVHDEAEE-SEDDFEEMNLSLLS----AR---S-FPRKASQTSIFL
KSR1_Hsap       VLEA-HEAEAEEPEAGKSEAED-DEDEVDDLPSSRRP----WR---GPISRKASQTSVYL
ksr-1_Cele      IVAN-HED-STGSQEVDSEAAP-SQEAVDKFNKRADGGFTWERHAWNMSTIRGPNAQASW
KSR1_Spur       SHDT-HDP-FTDSERTLPEQVE-PVDEVSDPE---PN----------ILLATRKNSQKLL
KSR2_Spur       -PENNCNS-NDQMVS----------DWTEEYRR-------------S--SLHYEAQKEGL
KSR1_Mmus       VLGV-HEAEAEEPEAGKSEAEDDEEDEVDDLPSSRRP----WR---GPISRKASQTSVYL
KSR2_Mmus       I--E-VEP-TSENEESHNEAEE-SEDEFEEMNLSLLS----AR---S-FPRKASQTSIFL
ksr_Dmel        YTDT-HKS--NDSDKTVSLSGS-ASTDSDRTPVRVDS----TE---DGDSGQWRQNSISL
AqueK675_Aque   LATD-SDV-FSDCYTDDEEEEE-EEDEIEEVPL-------------SVY------LQGKW
AqueK676_Aque   IMEG-SDD-DDDSYA-DSEGVG-SSGGLDEPEV-------------N--KYRIRHRNSVV
                      .                     .                           .

KSR2_Hsap       QEWDIPFEQLEIG---ELIGKGRFGQVYHGRWHGEVAIRLIDIERDN--EDQLKAFKREV
KSR1_Hsap       QEWDIPFEQVELG---EPIGQGRWGRVHRGRWHGEVAIRLLEMDGHN--QDHLKLFKKEV
ksr-1_Cele      NEVTIQFETIEFDKQAPIIGRGRFGKVLRGFHYGDVAVKVYTMEHISDASKKAEEFKLEV
KSR1_Spur       SEWDIPFEQLEIL---DLIGTGRFGAVH--------------------------------
KSR2_Spur       SEWTIPHANLKYG---RCIEKGKLGSTYKGHWHGEVLIQTR---YSKS--TDINDFLDEV
KSR1_Mmus       QEWDIPFEQVELG---EPIGQGRWGRVHRGRWHGEVAIRLLEMDGHN--QDHLKLFKKEV
KSR2_Mmus       QEWDIPFEQLEIG---ELIGKGRFGQVYHGRWHGEVAIRLIDIERDN--EDQLKAFKREV
ksr_Dmel        KEWDIPYGDLLLL---ERIGQGRFGTVHRALWHGDVAVKLLNEDYLQD-EHMLETFRSEV
AqueK675_Aque   KEWMVGSEEIQLY---GEAASSCKETVQKGYWHGNVWVHQRTIK--RQ--EDVRSFANEV
AqueK676_Aque   DEWIIPYNDLKLL---EKLGSGPVAEVYKGYWHGEVAVKRFVLPNATP--KQINKFREEV
                .*  :    :           .    .

KSR2_Hsap       MAYRQTRHENVVLFMGACMSPP---HLAIITSLCKG-RTLYSVVRDAKIVLDVNKTRQIA
KSR1_Hsap       MNYRQTRHENVVLFMGACMNPP---HLAIITSFCKG-RTLHSFVRDPKTSLDINKTRQIA
ksr-1_Cele      SAYKNTRHDNIALFLGYFMSDG---QYGMVMSLSKGSQSLYTLLHVVREKLDLATTRKIA
KSR1_Spur       -------------------------------NLCKG-QTLYTHIHLRKDRFNINRTIQIA
KSR2_Spur       AMLSKIRHENIALFMGACVEPG---NLAVVNSIHKG-PSLYHHLHVQRRKLQTSSKMDIA
KSR1_Mmus       MNYRQTRHENVVLFMGACMNPP---HLAIITSFCKG-RTLHSFVRDPKTSLDINKTRQIA
KSR2_Mmus       MAYRQTRHENVVLFMGACMSPP---HLAIITSLCKG-RTLYSVVRDAKIVLDVNKTRQIA
ksr_Dmel        ANFKNTRHENLVLFMGACMNPP---YLAIVTSLCKG-NTLYTYIHQRREKFAMNRTLLIA
AqueK675_Aque   NTLCCIRHENIQLFMGVCLDLPAGDTFGIIMSEVKG-DTLYNHIHKLGHNFTTPSKLKIL
AqueK676_Aque   AVLKKIRHENLALFMGVCLTTP---NLAIITSYCKG-YTLYKLLHYWSEAFSLERLANIG
                                               .  **  :*:  ::     :       *

KSR2_Hsap       QEIVKGMGYLHAKGILHKDLKSKNVFYDN----GKVVIT-DFGLFSISGVLQAGR--RED
KSR1_Hsap       QEIIKGMGYLHAKGIVHKDLKSKNVFYDN----GKVVIT-DFGLFGISGVVREGR--REN
ksr-1_Cele      QQICQAVSYLHTKKILHKDLRSKNILLESK---NKVVIT-DFGILSMKRLAHPKQ-K--S
KSR1_Spur       TQITQGMSYLHHKGIVHKDLKSKNIFIEN----GKVVLT-DFALFSIGRLSKQKT--RKD
KSR2_Spur       RQIGQAMGYLQAKGIIVGHLSSRCVYLESK---VKLSVT-RVDTS---DV--TCQ--RAS
KSR1_Mmus       QEIIKGMGYLHAKGIVHKDLKSKNVFYDN----GKVVIT-DFGLFGISGVVREER--REN
KSR2_Mmus       QEIVKGMGYLHAKGILHKDLKSKNVFYDN----GKVVIT-DFGLFSISGVLQAGR--RDD
ksr_Dmel        QQIAQGMGYLHAREIIHKDLRTKNIFIEN----GKVIIT-DFGLFSSTKLLYC-----DM
AqueK675_Aque   RQISEGMEYLHAKGIQHGGLSSKLVTINH----R-VCISLSFHN------------T--N
AqueK676_Aque   RQIAQAMGYLHARGIIHKGLNTKNIFLEKRDQKEKVIIT-DMGLSSLSSLLYDNTTSKGG
                 :* :.: **: : *    * :: :  :       : ::  .

KSR2_Hsap       KLRIQNGWLCHLAPEIIRQLSPDTE---EDKLPF--SKHSDVFALGTIWYELHAREWPFK
KSR1_Hsap       QLKLSHDWLCYLAPEIVREMTPGKD---EDQLPF--SKAADVYAFGTVWYELQARDWPLK
ksr-1_Cele      GYLTSKFWTNYIAPELAMAMRTEYDEYECDDFPF--SENSDVYAFGCVWFEMLTGALPYA
KSR1_Spur       SLVIPDGWLCYLAPELITSLKINTDGTQDMELPF--SEKSDVYSFGTIWYELLAGEWPFH
KSR2_Spur       HACLPRGKLQYLAPELLAKARVVPPE-FITGNEQ--THSTDVYAFGTILFEIIAGRWPLQ
KSR1_Mmus       QLKLSHDWLCYLAPEIVREMIPGRD---EDQLPF--SKAADVYAFGTVWYELQARDWPFK
KSR2_Mmus       KLRIQNGWLCHLAPEIIRQLSPDTE---EDKLPF--SKHSDVFALGTIWYELHAREWPFK
ksr_Dmel        GLGVPHNWLCYLAPELIRALQPEKPR--GECLEF--TPYSDVYSFGTVWYELICGEFTFK
AqueK675_Aque   NRQLEGCDLPYLTPEEIRSITQLSNGYLFLPTKP--TPSTDIFAFGTIAYELTTLKLPFL
AqueK676_Aque   VVTFPRAQLYSLAPEIIRKISPTPVV-QIDQEPYSYNYATDVYAFGTILYELITKRFPFS
                           ::**                     .  :*::::* : :*:     .

KSR2_Hsap       TQP------AEAIIWQMGT--GMKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLMDM
KSR1_Hsap       NQA------AEASIWQIGSGEGMKRVLTSVSLGKEVSEILSACWAFDLQERPSFSLLMDM
ksr-1_Cele      GEL------PHQILFAKTQ--GIRPVLPNVKCTQELKELLVSCWNTAPQDRPTLTDINLK
KSR1_Spur       KQP------VETVIWQVGK--GLKQPLNHLQASRDVKEILMMCWSYSPDSRPIFQHIKKT
KSR2_Spur       YAC------SESVIYQTCS--GRRDDFRNVTCSSTMKNLIQECWSQNPNERPSFQDIVKE
KSR1_Mmus       HQP------AEALIWQIGSGEGVRRVLASVSLGKEVGEILSACWAFDLQERPSFSLLMDM
KSR2_Mmus       TQP------AEAIIWQMGT--GMKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLMDM
ksr_Dmel        DQP------AESIIWQVGR--GMKQSLANLQSGRDVKDLLMLCWTYEKEHRPQFARLLSL
AqueK675_Aque   NQS------LLDLIWSVGN--NGHQSLKLLP-RSCFRSVIHRCWSHT--RRTTFKDILSS
AqueK676_Aque   TDSLGFAYEFEVVIFLVGH--GHRQPFKG-ETPKKLKDIVWECWSHQPQDRPPFSDLQER
                             ::      . :  :        . .::  **      *. :  :

KSR2_Hsap       LEKLPK----RNRRLSHPGHFWKSAE------------------------L
KSR1_Hsap       LEKLPK----LNRRLSHPGHFWKSADINSSKVVPRFERFGLGVLESSNPKM
ksr-1_Cele      LTALPKKP-RVNRSPSFPVMM-KSYE----------------------STF
KSR1_Spur       ILRLPKKK-GLHRSPSHPLHLSRSAE----------------------SVL
KSR2_Spur       LKKNVSL-GNMKHSLSEPDNLNRLGTG---------------------LFR
KSR1_Mmus       LERLPK----LNRRLSHPGHFWKSADINSSKVMPRFERFGLGTLESGNPKM
KSR2_Mmus       LEKLPK----RNRRLSHPGHFWKSA-------------------------E
ksr_Dmel        LEHLPKK--RLARSPSHPVNLSRSAE----------------------SVF
AqueK675_Aque   IQDNTSFPPTRFSSTSLPLSS-QHCT----------------------LRQ
AqueK676_Aque   LARLCRKHTPITRSPSHPINLSKSVDN--------------------LLHI
                :              * *    :