KSR2_Hsap LEI-GELIGKGRFGQVYHGRWHGEVAIRLIDIERDN--EDQLKAFKREVMAYRQTRHENV
KSR1_Hsap VEL-GEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHN--QDHLKLFKKEVMNYRQTRHENV
ksr-1_Cele FDKQAPIIGRGRFGKVLRGFHYGDVAVKVYTMEHISDASKKAEEFKLEVSAYKNTRHDNI
KSR1_Spur ------------------------------------------------------------
KSR2_Spur LKY-GRCIEKGKLGSTYKGHWHGEVLIQT---RYSK--STDINDFLDEVAMLSKIRHENI
KSR1_Mmus VEL-GEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHN--QDHLKLFKKEVMNYRQTRHENV
KSR2_Mmus LEI-GELIGKGRFGQVYHGRWHGEVAIRLIDIERDN--EDQLKAFKREVMAYRQTRHENV
ksr_Dmel LLL-LERIGQGRFGTVHRALWHGDVAVKLLNEDYLQ-DEHMLETFRSEVANFKNTRHENL
AqueK675_Aque -----------------------------------R--QEDVRSFANEVNTLCCIRHENI
AqueK676_Aque LKL-LEKLGSGPVAEVYKGYWHGEVAVKRFVLPNAT--PKQINKFREEVAVLKKIRHENL
KSR2_Hsap VLFMGACMSPP---HLAIITSLCKG-RTLYSVVRDAKIVLDVNKTRQIAQEIVKGMGYLH
KSR1_Hsap VLFMGACMNPP---HLAIITSFCKG-RTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLH
ksr-1_Cele ALFLGYFMSDG---QYGMVMSLSKGSQSLYTLLHVVREKLDLATTRKIAQQICQAVSYLH
KSR1_Spur ---------------------LCKG-QTLYTHIHLRKDRFNINRTIQIATQITQGMSYLH
KSR2_Spur ALFMGACVEPG---NLAVVNSIHKG-PSLYHHLHVQRRKLQTSSKMDIARQIGQAMGYLQ
KSR1_Mmus VLFMGACMNPP---HLAIITSFCKG-RTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLH
KSR2_Mmus VLFMGACMSPP---HLAIITSLCKG-RTLYSVVRDAKIVLDVNKTRQIAQEIVKGMGYLH
ksr_Dmel VLFMGACMNPP---YLAIVTSLCKG-NTLYTYIHQRREKFAMNRTLLIAQQIAQGMGYLH
AqueK675_Aque QLFMGVCLDLPAGDTFGIIMSEVKG-DTLYNHIHKLGHNFTTPSKLKILRQISEGMEYLH
AqueK676_Aque ALFMGVCLTTP---NLAIITSYCKG-YTLYKLLHYWSEAFSLERLANIGRQIAQAMGYLH
** :*: :: : * :* :.: **:
KSR2_Hsap AKGILHKDLKSKNVFYDN----GKVVITDFGLFSISGVLQAGR--REDKLRIQNGWLCHL
KSR1_Hsap AKGIVHKDLKSKNVFYDN----GKVVITDFGLFGISGVVREGR--RENQLKLSHDWLCYL
ksr-1_Cele TKKILHKDLRSKNILLESK---NKVVITDFGILSMKRLAHPKQ--KSG-YLTSKFWTNYI
KSR1_Spur HKGIVHKDLKSKNIFIEN----GKVVLTDFALFSIGRLSKQKT--RKDSLVIPDGWLCYL
KSR2_Spur AKGIIVGHLSSRCVYLESK---VKLSVTRVDT---SDV--TCQ--RASHACLPRGKLQYL
KSR1_Mmus AKGIVHKDLKSKNVFYDN----GKVVITDFGLFGISGVVREER--RENQLKLSHDWLCYL
KSR2_Mmus AKGILHKDLKSKNVFYDN----GKVVITDFGLFSISGVLQAGR--RDDKLRIQNGWLCHL
ksr_Dmel AREIIHKDLRTKNIFIEN----GKVIITDFGLFSSTKLLYC-----DMGLGVPHNWLCYL
AqueK675_Aque AKGIQHGGLSSKLVTINHR----VCISLSFH------------NT--NNRQLEGCDLPYL
AqueK676_Aque ARGIIHKGLNTKNIFLEKRDQKEKVIITDMGLSSLSSLLYDNTTSKGGVVTFPRAQLYSL
: * * :: : : . :
KSR2_Hsap APEIIRQLSPDTE---EDKLPFS--KHSDVFALGTIWYELHAREWPFKTQP------AEA
KSR1_Hsap APEIVREMTPGKD---EDQLPFS--KAADVYAFGTVWYELQARDWPLKNQA------AEA
ksr-1_Cele APELAMAMRTEYDEYECDDFPFS--ENSDVYAFGCVWFEMLTGALPYAGEL------PHQ
KSR1_Spur APELITSLKINTDGTQDMELPFS--EKSDVYSFGTIWYELLAGEWPFHKQP------VET
KSR2_Spur APELLAKARVVPPE-FITGNEQT--HSTDVYAFGTILFEIIAGRWPLQYAC------SES
KSR1_Mmus APEIVREMIPGRD---EDQLPFS--KAADVYAFGTVWYELQARDWPFKHQP------AEA
KSR2_Mmus APEIIRQLSPDTE---EDKLPFS--KHSDVFALGTIWYELHAREWPFKTQP------AEA
ksr_Dmel APELIRALQPEKP--RGECLEFT--PYSDVYSFGTVWYELICGEFTFKDQP------AES
AqueK675_Aque TPEEIRSITQLSNGYLFLPTKPT--PSTDIFAFGTIAYELTTLKLPFLNQS------LLD
AqueK676_Aque APEIIRKISPTPVV-QIDQEPYSYNYATDVYAFGTILYELITKRFPFSTDSLGFAYEFEV
:** : :*::::* : :*: .
KSR2_Hsap IIWQMGT--GMKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLM--------------
KSR1_Hsap SIWQIGSGEGMKRVLTSVSLGKEVSEILSACWAFDLQERPSFSLLM--------------
ksr-1_Cele ILFAKTQ--GIRPVLPNVKCTQELKELLVSCWNTAPQDRPTLTDINLKLTALPKKP-RV-
KSR1_Spur VIWQVGK--GLKQPLNHLQASRDVKEILMMCWSYSPDSRPIFQHIKK-------------
KSR2_Spur VIYQTCS--GRRDDFRNVTCSSTMKNLIQECWSQNPNERPSFQDIVKELKKNVSLG----
KSR1_Mmus LIWQIGSGEGVRRVLASVSLGKEVGEILSACWAFDLQERPSFSLLM--------------
KSR2_Mmus IIWQMGT--GMKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLM--------------
ksr_Dmel IIWQVGR--GMKQSLANLQSGRDVKDLLMLCWTYEKEHRPQFARLLS-------------
AqueK675_Aque LIWSVGN--NGHQSLKLLP-RSCFRSVIHRCWSHT--RRTTFKDILSSI-----------
AqueK676_Aque VIFLVGH--GHRQPFKG-ETPKKLKDIVWECWSHQPQDRPPFSDLQERLARLCRKHTPIT
:: . : : . .:: ** *. : :
KSR2_Hsap ------------DM
KSR1_Hsap ------------DM
ksr-1_Cele --------NRSPSF
KSR1_Spur ------------TI
KSR2_Spur -------NMKHSLS
KSR1_Mmus ------------DM
KSR2_Mmus ------------DM
ksr_Dmel ------------LL
AqueK675_Aque ------------QD
AqueK676_Aque RSPSHPINLSKSVD