PLK1_Hsap        -----FLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQH
F55G1.8_Cele     YEKGAFLGEGGFAHCFEFRKLDCNDRLAVKVVPKVILLKSTAREKLTREVEIHRQLSHRN
plk-1_Cele       YEKGRFLGKGGFAHCYELTNRATREVVAGKVVPKSMLVKQYQRDKMTQEVQIHRELGHIN
plk-2_Cele       YEKGKFLGKGGFAHCYELRNKSTGELFAGKVVPKALLIKQYQRDKMAQEVQIHRNLQHRN
PLK1_Spur        YTKGRFLGKGGFAKCYELTDDATKQIFAGKVVSKALLVKPHQKDKMTMEIHIHKSLHHRH
PLK1_Mmus        -----FLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQKEKMSMEISIHRSLAHQH
PLK_Ddis         YRQGEFLGKGGFAKCYLMTEVETNRIYAAKIIPKSTLQKTRARSKLKSEIKIHSSLSHEN
polo_Dmel        YKRMRFFGKGGFAKCYEIIDVETDDVFAGKIVSKKLMIKHNQKEKTAQEITIHRSLNHPN
CDC5_Scer        YHRGHFLGEGGFARCFQIKDD-SGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPN
CC1G_07437_Ccin  FNRVGFLGEGGFARVYEVQDP-RGSRLACKVVTKSALKTKKAKTKLYAEIKIHRSLDHPN
AqueK200_Aque    YEKGRFLGKGGFAKCYELICEETGTVYAGKIVAKELLVKPHQKEKMTQEIEIHRSLSHKH
                      *:*:****: : .         * * :.*  : .   : *   *: ** .: * :

PLK1_Hsap        VVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRV
F55G1.8_Cele     IVQFHHFFEDSQNVYFTLELCSKNSLMELNKQRGPLTEHEARFYTIQVAEGVKHLHNLQI
plk-1_Cele       IVKLFNFFEDNLNVYITLELCARRSLMELHKRRKAVTEPEARYFTHQIVDGVLYLHDLNI
plk-2_Cele       VVKLYHFFEDKSNVYITLELCPRRSLMELHKRRKAVTEPEARYFTYQIVEGVLYLHNLKI
PLK1_Spur        VVGFHSFFEDKENVYVLLELCRRRSLMELHKRRKAITEPETRYFMRQCILACQYLSKTKV
PLK1_Mmus        VVGFHDFFEDSDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNQV
PLK_Ddis         IVKFEHCFENEENVYILLELCNQKTVMDIHKKRKYLMEYETKYYVYQVIMAVQYLHNNNI
polo_Dmel        IVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITEFECRYYIYQIIQGVKYLHDNRI
CDC5_Scer        IVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRV
CC1G_07437_Ccin  IVTFIDCFEDEDNVYITLELCPSGSLMDMLRRRRRFTEPETRFFMVQLIGACHYMHTHQV
AqueK200_Aque    VVGFHGFFDDSNNVYILLELCKRRSLMELHKRRKALTEPEVRYLFRQTVLAVDYLHDVKV
                 :* :   *::.  ::. **:*   ::::: ::*  . * * ::   *   .  ::   .:

PLK1_Hsap        IHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLS--KKGHSF
F55G1.8_Cele     IHRDLKLGNLFLNEHLQVKIGDFGLATFCEK-NEKKMTRGGTPNYIAPEVLN--ETGHAF
plk-1_Cele       IHRDMKLGNLFLNDDLVVKIGDFGLATTVNG-DERKKTLCGTPNYIAPEVLN--KAGHSF
plk-2_Cele       VHRDLKLGNLFLNDELQVKIGDFGLATTCDN-DERKKTLCGTPNYIAPEVLN--KIGHSF
PLK1_Spur        IHRDLKLGNLFIDDNMELKVGDFGLATKVDFSGERKKTLCGTPNYIAPEVLS--KKGHSY
PLK1_Mmus        IHRDLKLGNLFLNEDLEVKIGDFGLATKVEYEGERKKTLCGTPNYIAPEVLS--KKGHSF
PLK_Ddis         IHRDLKLGNLFID-NMRIKLGDFGLSTKVEH-GERKKTICGTPNYIAPEILDN-SNGHSY
polo_Dmel        IHRDLKLGNLFLNDLLHVKIGDFGLATRIEYEGERKKTLCGTPNYIAPEILT--KKGHSF
CDC5_Scer        IHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSF
CC1G_07437_Ccin  IHRDLKLGNLFLDANMNVKVGDFGLAALIENPGERKKTICGTPNYIAPEVLFDTANGHSF
AqueK200_Aque    IHRDLKLGNLFLNDDIEIKLGDFGLATRLEEDGERKKTLCGTPNYIAPEVLT--KKGHSY
                 :***:****:*::    :*:*****::     .*:* *  *********:*     **::

PLK1_Hsap        EVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKH--INPVAASLIQKMLQT
F55G1.8_Cele     EVDIWAIGCILYVLLFGSPPFESRRVQETYVRIKNNDYVVPEN--ASPTANRLIRSLLDP
plk-1_Cele       EVDIWAVGCILYILLFGQPPFESKSLEETYSRIRHNNYTIPSI--ATQPAASLIRKMLDP
plk-2_Cele       EVDLWAIGCILYILLFGHPPFESKSLEETYSRIKNNNYVIPTS--ASAAASQLIRVLLDP
PLK1_Spur        EVDLWSLGCIMYTLLVGKPPFETQSLKDTYQRIKRNEYRVPSH--VSTPARNLIVKLLKN
PLK1_Mmus        EVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKH--INPVAASLIQKMLQT
PLK_Ddis         EVDVWSIGIILYTLLIGKPPFETSDVKHTYQRIKQNQYSFPDEPIISHYGKSLIISILNP
polo_Dmel        EVDIWSIGCVMYTLLVGQPPFETKTLKDTYSKIKKCEYRVPSY--LRKPAADMVIAMLQP
CDC5_Scer        EVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSL
CC1G_07437_Ccin  EVDIWSIGVILYTLVIGRPPFQTKEVKEIYKRIRDNEYEFPAERAISTAVKVLIQQILTP
AqueK200_Aque    EVDIWSLGCILYTLLVGKPPFETKTLKDTYQRIKRNEYHIPHY--VGPEARTLISNLLRP
                 ***:*::* ::* *:.* ***::  ::  * :*:  :: .*           ::  :*

PLK1_Hsap        DPTARPTINELLNDEFF
F55G1.8_Cele     VPDRRPTAEAVLLDQFF
plk-1_Cele       EPTRRPTAKQVIS---I
plk-2_Cele       VPSRRPNARAVCRDHFF
PLK1_Spur        DPTQRPHIDILLQDEFF
PLK1_Mmus        DPTARPTIHELLNDEFF
PLK_Ddis         VPEQRPNLTQILEH-DF
polo_Dmel        NPESRPAIGQLLNFEFL
CDC5_Scer        DPIERPSLTEIMDYVWF
CC1G_07437_Ccin  DPSQRPTLHEIIEDTFF
AqueK200_Aque    NPANRPTAAEILKDPFF
                  *  **    :     :