NEK2_Hsap MPS------------------RAEDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYG
NEK2_Mmus MPS------------------RVEDYEVLHSIGTGSYGRCQKIRRKSDGKILVWKELDYG
Nek2_Ddis ----------------------MDQYEILGALGKGSFGVVSKIKRKEDGRVLVWKEICYE
Nek2_Dmel MSGEES------AGMD-FSQKTLQDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYD
KIN3_Scer MHRRQFFQEYRSPQQQQGHPP-RSEYQVLEEIGRGSFGSVRKVIHIPTKKLLVRKDIKYG
NEK2_Spur MPS------------------KLSDYDILYTIGSGSYGKCRKVRRKSDGKILVSKEIDYG
CC1G_04175_Ccin MSA------------------FLEQYEPLDVIGNGSFGIIRKVRRKSDGLIFARKELNFE
AqueK179_Aque MPS-----------------GKLDDYVVVGMIGSGSFGQCKKIRRICDGKVLVWKEINYK
.:* : :* **:* *: ::. * : :
NEK2_Hsap SMTEAEKQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGT
NEK2_Mmus SMTEVEKQMLVSEVNLLRELKHPNIVSYYDRIIDRTNTTLYIVMEYCEGGDLASVISKGT
Nek2_Ddis NMQEKEKQLLVNEVNILQKLKHQNIVRYYDRIIDKPSSRLYIIMEHCSGGDLSQLIKKCR
Nek2_Dmel ELDEAKCDALVSEISVLRQLQHPNIVQYYHHLVNREAKSVYIVMECCAGGDLAQIVQRAR
KIN3_Scer HMNSKERQQLIAECSILSQLKHENIVEFYNWDFDEQKEVLYLYMEYCSRGDLSQMIKHYK
NEK2_Spur TMGEVEKQMLVSEVNLLRELKHEFIVRYYDRIVDRATSTIYIIMEYCEGGDLGSLISKCK
CC1G_04175_Ccin RMSERDRKQIVAEVNILKDLHHEHIVRYHDRHVDRDAGILYIIMEYCGGGDLSTVIKQAA
AqueK179_Aque EMTESEKQQLVTEVNLLRELKHTHIVQYYDRIIDRSQSMLYIITEYCPGGDLATLISQHR
: . . . :: * .:* .*:* ** ::. .:. :*: * * ***. :: :
NEK2_Hsap KERQYLDEEFVLRVMTQLTLALKECHRRSD---------------G-G------------
NEK2_Mmus KDRQYLEEEFVLRVMTQLTLALKECHRRSD---------------G-G------------
Nek2_Ddis NERTYMDEEVIWRTLLQILSALQEIHNRKD------------------------------
Nek2_Dmel SQRQRFEEPYIWRVLFQLCRALQVCHNKIP---------------N--------------
KIN3_Scer QEHKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRMKPPVKGK------------
NEK2_Spur KDRKFLEESFAWKIFQQLTIALQECHRRGK-----------------G------------
CC1G_04175_Ccin KHNRPISEDLIWNYFMQILLALHHCHHPNG---------------H-GRSGSGSGSALTE
AqueK179_Aque HQRKLLPECFIWQVMHQILLALEECHRSKE---------------NVG------------
.. : * : *: ** *
NEK2_Hsap ---------HTVLHRDLKPANVFLDGKQ--------------------------------
NEK2_Mmus ---------HTVLHRDLKPANVFLDSKH--------------------------------
Nek2_Ddis ---------GVILHRDIKPGNLFLDENK--------------------------------
Nek2_Dmel ---------GTILHRDIKPANIFLDAAG--------------------------------
KIN3_Scer ---------NIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGS
NEK2_Spur ---------RAILHRDLKPANVFLDADH--------------------------------
CC1G_04175_Ccin GEGGGSSRRPQILHRDLKPDNVFLDENN--------------------------------
AqueK179_Aque ---------GKVMHRDIKPANVFLDGEG--------------------------------
::***:** *:**.
NEK2_Hsap -------NVKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLL
NEK2_Mmus -------NVKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQMSCLSYNEKSDIWSLGCLL
Nek2_Ddis -------NIKLGDFGLAKILN-ESLYAHTFVGTPYYMSPEQIHGLKYNERSDVWSVGCLI
Nek2_Dmel -------NAKLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGRKYDRKSDVWAVGCLV
KIN3_Scer PMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVI
NEK2_Spur -------NVKLGDFGLARVLQHDTSFAKTFVGTPYYMSPEQMNRLSYNDKSDIWSLGCLL
CC1G_04175_Ccin -------NVKLGDFGLSKALN-QASFANTYVGTPYYMSPELMQEKAYDSKSDIWSLGCLI
AqueK179_Aque -------QVKLGDFGLARILH-NTSLAKTFVGTPYYMSPEQYSCNSYDHRSDLWSIGCLL
*******:: *. . * ::****:***** *. **:*::**::
NEK2_Hsap YELCALMPPFT-AFSQKELAGKIREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEI
NEK2_Mmus YELCALMPPFT-AFNQKELAGKIREGRFRRIPYRYSDGLNDLITRMLNLKDYHRPSVEEI
Nek2_Ddis YEMATLSPPFE-ATNQAQLTSKIQVGRYNPIPSQYSEHLSKVISLMINVDPKSRPNVNEL
Nek2_Dmel YEMCALRPPFR-GRAFDQLSEKIAQGEFSRIPAIYSTDLQEIIAFMLAVDHEQRPGIEVI
KIN3_Scer FEMCSLHPPFQ-AKNYLELQTKIKNGKCDTVPEYYSRGLNAIIHSMIDVNLRTRPSTFEL
NEK2_Spur YELCSLSPPFT-ATNQAALAVKIKGGHFRRLPVQYSSDLNEIVSSMLKVKPSSRPSIDEL
CC1G_04175_Ccin YELCALKPPFHEAKTHNELSILIRNGRIPPLPRGYSQALFGVIKAMLNLNPAMRPSAAQL
AqueK179_Aque YELCALKPPFV-ASSQYKLAEYVCNGRFSRIPSKYSDDLHWTISQLLHVKPEKRPLLSQL
:*:.:* *** . * : *. :* ** * : :: :. ** :
NEK2_Hsap LENPLIADL--VADE---------------------------------------------
NEK2_Mmus LESPLIADL--VAEE---------------------------------------------
Nek2_Ddis LGYSFISFK--VKE----------------------------------------------
Nek2_Dmel IRHPLVVRN--ISELDGKFPILVDSGEDFYTLPSGARLFEDEEEDGVHPELSSTMFTEQY
KIN3_Scer LQDIQIRT--AR------------------------------------------------
NEK2_Spur LADPRLSPP--PSQV---------------------------------------------
CC1G_04175_Ccin LQHERLELVFKVAETE--------------------------------------------
AqueK179_Aque LSLLEEKIP--LAKP---------------------------------------------
:
NEK2_Hsap -----------------------------------------------------------Q
NEK2_Mmus -----------------------------------------------------------Q
Nek2_Ddis -----------------------------------------------------------R
Nek2_Dmel SFNEGYGQRRLSVTGVFTPDLRSELFYSAKRKIFPAKKLQLSDPSLYESIRREERA-EER
KIN3_Scer -----------------------------------------------------------K
NEK2_Spur -----------------------------------------SS---------ADAP-KEA
CC1G_04175_Ccin ---------------------------------------KMLS-----TVK---AH-KN-
AqueK179_Aque --------------------------------------PNVAG---------TEKTTPPS
NEK2_Hsap RRNLERRGRQL-------------------------------------------------
NEK2_Mmus RRNLERRGRRS-------------------------------------------------
Nek2_Ddis KLNIYYQG----------------------------------------------------
Nek2_Dmel QVELAEERRRK---------KDQEQQ----------------------------------
KIN3_Scer SLQLER------------------------------------------------------
NEK2_Spur EVDLLKKEREA-------------------------------------------------
CC1G_04175_Ccin --AMVAREREVLAREQIIAEKEQHLQHLFSQKDSEIAHLQRVVSQLQAQIHTIQSEPRIT
AqueK179_Aque VLGAVKE-----------------------------------------------------
NEK2_Hsap ------------------------------------------------------------
NEK2_Mmus ------------------------------------------------------------
Nek2_Ddis ------------------------------------------------------------
Nek2_Dmel ---------------------------------------------------------KRD
KIN3_Scer ------------------------------------------------------------
NEK2_Spur ------------------------------------------------------------
CC1G_04175_Ccin QHDLEVATKHAVARREQELRILVQKREEEVAAAMAKREEEIMEAVRRREAEVCEAWAKRE
AqueK179_Aque ------------------------------------------------------------
NEK2_Hsap GEPEKSQDSSPVLSELKLKEIQLQERERALKAREERLEQK----EQELC-VRERLAE---
NEK2_Mmus GEPSKLPDSSPVLSELKLKERQLQDREQALRAREDILEQK----ERELC-IRERLAE---
Nek2_Ddis --------LKQMDEDLKIKEKKLSDIERDLQVKEQHLLLR----EQQIN-QREKLLL---
Nek2_Dmel QELLKEAPSSPRALTQNIFDEVLKTRLHAIRAQESLLQQK----LEELQ-TREQELQLAE
KIN3_Scer ------------------FERKLLDYENELTNIEKILEKQAIEYERELSQLKEQFTQAVE
NEK2_Spur --------LLAREESLKLKERNADKRTQMLNDREKELDLR----ERSLA-ARERLVK---
CC1G_04175_Ccin AEVRQEVE---------VSIKAVEERIQWISEKEAELIEE----EERLE-ALREELEVRE
AqueK179_Aque ------------EESLQRKLDELHRKEEILRKKEEDLQRK----EIELK-RREEVLV---
. : * * . : ..
NEK2_Hsap DKLARA-ENLLKNY----SLLKERK-----------FLSL-AS-----------------
NEK2_Mmus DKLARA-ESLMKNY----SLLKEHR-----------LLCL-AG-----------------
Nek2_Ddis DKENFETQSRIN--IMNQQLQQQQQNQLQHQ-----I-----------------------
Nek2_Dmel QRVQTL-ERQMQEK----LLQQEKHT-CSCRQPIAPPIPPRKPAKSHHDDTYCTIELNET
KIN3_Scer ---ERA-REVISGK----------------------------------------------
NEK2_Spur DKMSRA-EELIEEH----EKQQKQIPKVITR-----VTEL-RR-----------------
CC1G_04175_Ccin ---KRV-EELANKKGRTKSPLEEIRNTME-P----------TPQRR--------------
AqueK179_Aque ------------------------------------------------------------
NEK2_Hsap -----NPELLN-L-PSSV-IKKKVHF--------------SG------------------
NEK2_Mmus -----GPE-LD-L-PSSA-MKKKVHF--------------HG------------------
Nek2_Ddis ------S-NLSLNCNNSVNS-----C--------------SS------------------
Nek2_Dmel SPTVAKLNLATLPAPKSLNTLRKVTF--------------KS-----------PQKF--V
KIN3_Scer -------KV--GKVPESINGY---------------------------------------
NEK2_Spur -----QKEYLEGMHPTTLKTKKHVHF--------------QQ------------------
CC1G_04175_Ccin -------N-YD-PPPSTIK-RNRVDSTPRATTKQMFPAALETPITRPSYTDYLPSAMKGV
AqueK179_Aque ------------------------------------------------------------
NEK2_Hsap --------------------------------------ESKENIMR-SENSESQL-----
NEK2_Mmus --------------------------------------ESKENTAR-SENSESYL-----
Nek2_Ddis --------------------------------------SSNNNTTNS-INTQQQIH----
Nek2_Dmel ---TYG-IENMPPPA-VKPAVN-PPPTGVPMQMSVSSNDSGDSQAS-STRRKSILSLFGL
KIN3_Scer ----YGKKFAK-------------------------------------------------
NEK2_Spur ---------------------------------------GKENNPASHEGEPAVP-----
CC1G_04175_Ccin VLTSTGETLATPSPNELATLFNASPKVGLNFGKIFDFGEGDDDVTS-PTNTTTRLSLGGA
AqueK179_Aque ------------------------------------------------------------
NEK2_Hsap -----------------------------------------------TSKSKCKDLKKR-
NEK2_Mmus ------------------------------------------------AKSKCRDLKKR-
Nek2_Ddis ------------------------------------------------------------
Nek2_Dmel SRGSKATSKSLPSVNQVAQAAATRVQRPPLAVKPPITQEQPAEVPP-VANLWTKEQKKQA
KIN3_Scer ------------------------------------------------------------
NEK2_Spur -----------------------------------------------SADSKMTNLKER-
CC1G_04175_Ccin GSGLNGVGAS--GVN-------GGVQFP----NGAGSESDEDDAPPSPTTRKERELRER-
AqueK179_Aque ------------------------------------------------------------
NEK2_Hsap -----------------------------LHAAQ-LRA----------------------
NEK2_Mmus -----------------------------LHAAQ-LRA----------------------
Nek2_Ddis ----------------------------IQHNTQ-QQQ----------------------
Nek2_Dmel FELLAAMNAAEREASGGGVVGSGPGGARRQHLRQ-SVR----------------------
KIN3_Scer ------------------------------------------------------------
NEK2_Spur -----------------------------LYQAK-LRG----------------------
CC1G_04175_Ccin -----------------------------AESRSSLGGGEDATVTIAMNLGSATNGASVS
AqueK179_Aque ------------------------------------------------------------
NEK2_Hsap ---QALSDI------------EKNYQLK---SRQILGMR
NEK2_Mmus ---QALADI------------EKNYQLK---SRQILGMR
Nek2_Ddis ---QQQQT-------------FQPYQIKRTFTTPLPNFK
Nek2_Dmel ---ERNSTLQRNRMRRSLVVATGHQKLT---T-RDQMVI
KIN3_Scer ----------------------PAY----H---WQTRYR
NEK2_Spur ---LALRKA------------EMTSKLK---SKQLLSLR
CC1G_04175_Ccin TPTQASEDVYLGWVAPPYAYVGFESEVV---GDYAFGVG
AqueK179_Aque --------------------------LR---EKQQAILK