NEK1_Hsap MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH
NEK5_Hsap MDKYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKH
NEK3_Hsap MDDYMVLRMIGEGSFGRALLVQHESSNQMFAMKEIRLPKS-FSNTQNSRKEAVLLAKMKH
NEK1_Mmus MEKYVRLQKIGEGSFGKAVLVKSTEDGRHYVIKEINISRMSDKERQESRREVAVLANMKH
NEK3_Mmus MDNYTVLRVIGQGSFGRALLVLQESSNQTFAMKEIRLLK---SDTQTSRKEAVLLAKMKH
NEK5_Mmus MDNFHLIKIIGEGTFGKVYLAKDKSESSHCVIKEISLT----KEKEASKNEVILLARMEH
Nek3_Ddis MDKYEEIKTIGKGSFGRAILVKRKSDGLLLVLKEINVMEMQPKERSDAMNEVNLLSMLDH
AqueK176_Aque MDQYTRIRKIGEGSYGRALLVKGRQDGRQYVIKVINLSKMDRRGREEARREVKVLSQMKH
GK072_Glam MEHYTVIRKIGEGSFGECFLCCDKRTGLHVVIKEISMEDMQDTEVRNTERESAILLTMDH
GK270_Glam MERYKELKVLGKGSFGRAVLAQEKSTGIKYVMKVIHIAPLKPREREEALTEAKILSKLKH
*: : :: :*:*::*. * . .:* * . : * :* :.*
NEK1_Hsap PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQ--KGVLFQEDQILDWFVQICLALKH
NEK5_Hsap PNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQ--RGVLFSEDQILGWFVQISLGLKH
NEK3_Hsap PNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQ--KGKLFPEDMILNWFTQMCLGVNH
NEK1_Mmus PNIVQYKESFEENGSLYIVMDYCEGGDLFKRINAQ--KGALFQEDQILDWFVQICLALKH
NEK3_Mmus PNIVAFKESFEAEGYLYIVMEYCDGGDLMQRIKQQ--KGKLFPEDTILNWFIQICLGVNH
NEK5_Mmus PNIVTFFSSFQENGRLFIVMEYCDGGDLMQRIQRQ--RGVMFSEDQILCWFVQISLGLKH
Nek3_Ddis ENIIGYYDSFILNGCLYIIMEYANAGDINLEIKKRTLQNKTFSEFEILSWFSQICKALQY
AqueK176_Aque PNIVSYKDSFEETGSLYIVMDYCDGGDLYKHINAQ--RGRLFPEDQILNWFVQLCLALKH
GK072_Glam PNIVRGIESFKEDGFLYIAMTYCEHGELTSLIKRHHKSQMHFEESQVLRWIAQLASALWY
GK270_Glam PYIVGYHESFADTRYLHIVMEYADAGDLTDAIKRQKMKNSLFPEDQIWDWFVQICMALKH
*: .** *.* * *.: *:: *: : * * : *: *:. .: :
NEK1_Hsap VHDRKILHRDIKSQNIFLTK-D------GT-VQLGDFGIARVLNSTVELARTCIGTPYYL
NEK5_Hsap IHDRKILHRDIKAQNIFLSK-N------GMVAKLGDFGIARVLNNSMELARTCIGTPYYL
NEK3_Hsap IHKKRVLHRDIKSKNIFLTQ-N------GK-VKLGDFGSARLLSNPMAFACTYVGTPYYV
NEK1_Mmus VHDRKILHRDIKSQNIFLTK-D------GT-VQLGDFGIARVLNSTVELARTCIGTPYYL
NEK3_Mmus IHKRRVLHRDIKSKNVFLTH-N------GK-VKLGDFGSARLLSSPMAFACTYVGTPYYV
NEK5_Mmus IHDRKILHRDIKSQNIFLSK-N------GMVAKLGDFGTARTLNDSMELAQTCAGTPYYL
Nek3_Ddis ISSRNILHRDLKTQNIFLSIVNG----DYF-IKLGDFGIAKILNSETSLASTVLGTPYYL
AqueK176_Aque VHDRKILHRDIKSQNVFLTK-R------GV-VKLGDFGIARVLNSTVELARTCIGTPYYL
GK072_Glam IHSKGLIHRDLKSQNIFLDQ-D------LN-VHIGDFGIARTINP-GSMASTFIGSPLYM
GK270_Glam VHDRKILHRDLKTQNIFLCT-DENDRSRKT-VKLGDFGIAKILQSTLECARTAIGTPYYL
: .: ::***:*::*:** ::**** *: :. * * *:* *:
NEK1_Hsap SPEICEN-KPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSY
NEK5_Hsap SPEICQN-KPYNNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSR
NEK3_Hsap PPEIWEN-LPYNNKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLPSHYSY
NEK1_Mmus SPEICEN-KPYNNKSDIWALGCVLYELCTLKHAFEAGNMKNLVLKIISGSFPPVSPHYSY
NEK3_Mmus PPEIWEN-LPYNNKSDIWSLGCILYELCALKHPFQANSWKNLILKICQGPIHPLPALYSC
NEK5_Mmus SPEICQN-RPYNNKTDIWSLGCVLYELCTLKHPFESNNFHHLVLKICQGRVAPISPHFSR
Nek3_Ddis SPELIQNEKGYDHKSDIWSLGCVLYELTTLKHAFNAANLPALVLKILKGTYPPIPSHYSN
AqueK176_Aque SPEICEN-RPYNNKSDIWALGCVLYEMATLRHAFEAGNMRNLIVKIVRGSYPPLSSQYSR
GK072_Glam SPELIQG-TSYNSQSDMWSLGCMIFEILCLKTAFQAKNINTLIMKIVSGKVPELPGIYSS
GK270_Glam SPELCED-KPYNNKSDIWSLGCVLYEICTLQHAFEAQNMKGLVVKILRGQYQPISNTYSR
.**: :. *: ::*:*:***:::*: *: .*:. . *::*: . :. :*
NEK1_Hsap DLRSLVSQLFKRNPRDRPSVNSILEKGFIAKRIEKFLSPQLI--AEEF-CLKTFSKFGSQ
NEK5_Hsap ELHSLISQLFQVSPRDRPSINSILKRPFLENLIPKYLTPEVI--QEEF-SHMLICRAGA-
NEK3_Hsap ELQFLVKQMFKRNPSHRPSATTLLSRGIVARLVQKCLPPEII--MEY-------------
NEK1_Mmus DLRSLLSQLFKRNPRDRPSVNSILEKGFIAKRIEKFLSPQLI--AEEF-CLKTLSKFGPQ
NEK3_Mmus KLQGLVKQMLKRNPSHRPSATTLLCRGSLAPLVPKCLPPQII--REY-------------
NEK5_Mmus DLQSLIPQLFRVSPQDRPSVTSLLKRPFLETLIARSLYPEVC--SRRIQSHAHMENMAI-
Nek3_Ddis DLRNLISSMLQIDPKNRPSVNDILELPFINQYLGIPLKPFDSNLNENN-NDS-LNISNNS
AqueK176_Aque NLRSLVDSCLKNAPRDRPSINSILRLPFIQERIGKLLSETVS--AEEF-SHTVLHKKKTE
GK072_Glam KLRDICLNLLNQVPDQRMTAAQLCGHDLIAPFIFELNLPHP----ESFD-----------
GK270_Glam NLREVLDRMLQKDPNKRPSVNQILKLPFLQERIRRLLPEDYW--NEEF-SHTIIHGRGNA
.*: : :. * .* : : : : .
NEK1_Hsap PI---------PAKRPASGQN---SISVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKP
NEK5_Hsap ------------------------------------PASRHAGKVVQK---------CKI
NEK3_Hsap --------------------------------------------------GEEVLEEIKN
NEK1_Mmus PL---------PGKRPASGQG---VSSFVPAQKITKPAAKYGVPLTYKKYGDKKLLEKKP
NEK3_Mmus --------------------------------------------------GEQILDEIKI
NEK5_Mmus ------------------------------------------------------------
Nek3_Ddis -----------SG---------SNNS---------------A------------------
AqueK176_Aque PV---------PKPLPLKKE---------PPQIV--EGVKIGLKAQGGVGGDKKVDERRV
GK072_Glam -----------------------------PPT------AA--------------------
GK270_Glam LVGFGAGRVGIPGK-PVSGVPPKDDASSEASSAGRQPASRHGPPSAHPP--------PPP
NEK1_Hsap LQK-HKQAHQTPEKRVNTGEERRKI----------SEEAA-RKRRLEFIEKEKKQK----
NEK5_Hsap QKV-RFQGKCPPRSRISVPIKRNAIL--HRNEWRPPAGAQ-KARSIKMIERPKIA-----
NEK3_Hsap SK------HNTPRKKTNPSRIRIAL----------GNEAS-TVQE-E-------------
NEK1_Mmus PPK-HKQAHQIPVKKMNSGEERKKM----------SEEAA-KKRRLEFIEKEKKQK----
NEK3_Mmus ST------PKNMK-KQDSNRVRRAL----------GEANSASMQE-E-------------
NEK5_Mmus -------------------------G--PTACWR--------------------------
Nek3_Ddis ---------------------SNN----------ISSS-----------TEVKDQK----
AqueK176_Aque SAEERRRVVLKPKQRMSEGGKKPSPGLLAK--KKELEEKA-RAQREE-INQQRKSE----
GK072_Glam ------------------------V----------GNAFASRLSK-S-------------
GK270_Glam SQQ-NKPMYFNPNGGYQPPAANQK----------LSAAEV-AAMAIKNNQRPPPPVNQYQ
NEK1_Hsap -----------------------DQIISLMKAEQMKRQEKERLERI--------------
NEK5_Hsap ------------------------------------------------------------
NEK3_Hsap ------------------------------------------------------------
NEK1_Mmus -----------------------DQI-RFLKAEQMKRQEKQRLERI--------------
NEK3_Mmus ------------------------------------------------------------
NEK5_Mmus ------------------------------------------------------------
Nek3_Ddis -----------------------FQNIPLAMARNINNNNNNNNNNNNNNNNNNNNNNNNN
AqueK176_Aque -----------------------AQ---MKLHQQLKKQELLR------------------
GK072_Glam ------------------------------------------------------------
GK270_Glam SNVKQPGIMPGAIAVGVPGAPPVVQVNNKLSYDEIVRQEKQRIEEQ--------------
NEK1_Hsap ------------------------------------------------------------
NEK5_Hsap ------------------------------------------------------------
NEK3_Hsap ------------------------------------------------------------
NEK1_Mmus ------------------------------------------------------------
NEK3_Mmus ------------------------------------------------------------
NEK5_Mmus ------------------------------------------------------------
Nek3_Ddis NNNNNNNNNNNNNNNKSNVDDVNSSSTTTTSSSIVKSKVNTTVSPPLSPKKPITTTTTKT
AqueK176_Aque ------------------------------------------------------------
GK072_Glam ------------------------------------------------------------
GK270_Glam ------------------------------------------------------------
NEK1_Hsap ------------------------------------------------------------
NEK5_Hsap ------------------------------------------------------------
NEK3_Hsap ------------------------------------------------------------
NEK1_Mmus ------------------------------------------------------------
NEK3_Mmus ------------------------------------------------------------
NEK5_Mmus ------------------------------------------------------------
Nek3_Ddis TSLKTTPSIKPTLVKTPTIKSSLVKTPLSKTPISGTKNPTTSKITPSIKTPLPKAPISSK
AqueK176_Aque ------------------------------------------------------------
GK072_Glam ------------------------------------------------------------
GK270_Glam ------------------------------------------------------------
NEK1_Hsap -----------NRAREQG-WR-NVLSAGGSGEVKAPFLGSGGTIAPSSFSSRGQYEHYHA
NEK5_Hsap -------------------------------------------------AVCGHYDYYYA
NEK3_Hsap ------------------------------------------------------------
NEK1_Mmus -----------NRAREQG-WR-NVLRAGGSGEVKASFFGIGGAVSPSPCSPRGQYEHYHA
NEK3_Mmus ------------------------------------------------------------
NEK5_Mmus ------------------------------------------------------------
Nek3_Ddis TPTRLVSKPTTPKITTPKSTSTMI------------------------TPKRTTTTTTTP
AqueK176_Aque -------------RQQD-QQR-AVINW-------------QANISP------------HS
GK072_Glam ------------------------------------------------------------
GK270_Glam -----------RRRYQEDQAR-AQ------------------------EKVRQDYIKYHA
NEK1_Hsap IFDQMQQQRAEDNEAKWKREIYGRGLPERGILPGVRPGFPYGAAGHHHFPDADDIRKTLK
NEK5_Hsap QLDMLRR-RAHK--------------------PSYHP-IPQENTG---------------
NEK3_Hsap ------------------------------------------------------------
NEK1_Mmus IFDQMQRLRAEDNEARWKGGIYGRWLPERGVPPGVRPGFPSEASGHYHSPDAGAIRKTLK
NEK3_Mmus ------------------------------------------------------------
NEK5_Mmus ------------------------------------------------------------
Nek3_Ddis TP----------------------------------------------------------
AqueK176_Aque STDE--------------------------------------------------------
GK072_Glam ------------------------------------------------------------
GK270_Glam AQQENRGYHAV----------QGNPFAK------KQAQQASGAPGAGHAPSADMLDAKFA
NEK1_Hsap RLKAVSKQANAN-RQKGQLAVERAKQVEEFLQRKREAMQNKARAEGHMGILQNLA---AM
NEK5_Hsap ----VEDYGQET-RH----GPSPSQWPAEYLQRKFEAQQYKLKVEKQLGL----------
NEK3_Hsap ------------------------------------------------------------
NEK1_Mmus RLKAVSKQASTN-RQKGHLAVERANQVEEFLQRKREAMQNKARAEGH-GLLQNLA---SL
NEK3_Mmus ------------------------------------------------------------
NEK5_Mmus ----------------------VSPWSAAYLQRKFEAQQYKLKVERQLGL----------
Nek3_Ddis -------------------------------------TTA--------------------
AqueK176_Aque ----SSHQAKSETADEEPVKVDRQQIVSDFHQVRQEAAANKARAQAQLMGGANLGVGVAK
GK072_Glam ----ISDQAISE-AD----IFSNTSKINIYIKQGVEAENNAIQSIRQGG-----------
GK270_Glam DL-------------------------QDFINRPVAAQQP--------------------
NEK1_Hsap YGGRPSSSR------------GGKPR---------------N-KEEE-VYLARLRQIRLQ
NEK5_Hsap ---RPSSAEPNYNQRQELRSNGEEPRF----QELPFR---KNEMKEQ-EYWKQLEEIRQQ
NEK3_Hsap ------------------------------------------------------EQDRKG
NEK1_Mmus YGGRPSSSR------------GGKPR---------------N-NEEEVVYLARLRQIRLQ
NEK3_Mmus ------------------------------------------------------ERGRKC
NEK5_Mmus ---RPSSVEPHPNEGEKLQSHWEETKF----QELQYR---KNKMKDQ-EYWKQLEEIRQQ
Nek3_Ddis ----------TTTPKKSSLSSSSSSSVKPPPPTTTTTTPSKDR-----------------
AqueK176_Aque QGGVVKPVE-------------NKPP---------------N-NAEQ-EYLARLEDIRRQ
GK072_Glam --ASPTYSTG-----RRMT-----------------------------------------
GK270_Glam ----------QPSRQSQAPSISQSPTRQQQQQQQQQQ---QQQ-----------------
NEK1_Hsap NFNERQQIKAKLRGEKKEANHSEGQEGSEEADMRRKKIESLKAHANARAAVLKEQLERKR
NEK5_Hsap YHNDMKEIRKKMGREPEENSK-----ISHK--TYLVKKSNLPVHQDASEGEAPVQMEF--
NEK3_Hsap SHTDLESI----------------------------------------------------
NEK1_Mmus NFNERQQIKAKLRGENKEADGTKGQEATEETDMRLKKMESLKAQTNARAAVLKEQLERKR
NEK3_Mmus SHTELEST----------------------------------------------------
NEK5_Mmus YHNDMKEIKKKMGRELKRV-----------------------------------------
Nek3_Ddis --SSVNTINKPMASNLS-------------------------------------------
AqueK176_Aque NFQERKRVQERVSMYCHGNQAPPIPIPKVNPEARRKKIAALKAQAESESVKLREQVELKQ
GK072_Glam ------------------------------------------------------------
GK270_Glam --QRDQAIRRNIEE----------------------------------------------
NEK1_Hsap KEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHETGGSPSKQQ-MRSVISVTSALK-----
NEK5_Hsap ---------------------------------RSCCPGWSAMARSWLTATSASQDIEKD
NEK3_Hsap ----------------------------------NENLVESAL-----------------
NEK1_Mmus KEAYEREKKVWEEHLVA-RVKSSDVPLPLELLETGGSPSKQQ-VKPVISVTSALK-----
NEK3_Mmus ----------------------------------GTTPAGNAL-----------------
NEK5_Mmus ------------------------------------------------------------
Nek3_Ddis ------------------------------------------------------------
AqueK176_Aque KQRAA-------------------------------------------------------
GK072_Glam ------------------------------------------------------------
GK270_Glam ------------------------------------------------------------
NEK1_Hsap ---------------------------EVGVDSSLTDT--RETSEEMQKTNNAISSKREI
NEK5_Hsap LKQMRLQNTKESKNPEQKYKAKKGVKFEINLDKCISDENILQEEEAMDIPNETLTFED--
NEK3_Hsap ------------------------------------------------------------
NEK1_Mmus ---------------------------EVGLDGSLTDT--Q--EEEMEKSNSAISSKREI
NEK3_Mmus ------------------------------------------------------------
NEK5_Mmus ------------------------VKFEISLDKCISEEDTVQENEAVDKLNATLSFED--
Nek3_Ddis ------------------------------------------------------------
AqueK176_Aque ------------------------------------------------------------
GK072_Glam ------------------------------------------------------------
GK270_Glam ------------------------------------------------------------
NEK1_Hsap LRRLNENLKAQEDEKGKQN---LSDTFEINV-HEDAKEHE-----KEKSVSSDRKKWEAG
NEK5_Hsap ------GMKFKEYECVKEHGDYTDKAFEKLH-CPEAGFST-----QTVAAVGNRRQWDGG
NEK3_Hsap -R----------------------RVNREEK-GNKSVHLR-----KASSPNLHRRQWEKN
NEK1_Mmus LRRLNENLKAQEDEKEKQH---HSGSCETVG-HKDEREYE-----TENAISSDRKKWEMG
NEK3_Mmus -E----------------------RAARGNP-GNPQEHGR-----HTSPASPHRPWWERH
NEK5_Mmus ------GTKFQEHRCKEEHEDYTDRAFEELC-GPEAEGFF-----QDVIAAENRRQWDAG
Nek3_Ddis ---------SQISSSSSSS---SSSNSQFRPTTPSKERMSPTSTSTKSPTNPS---PTLS
AqueK176_Aque --------------------L-------------------------HSNVSPPRKQWVVP
GK072_Glam ----------------------------------------------------------G-
GK270_Glam -------------------------------QRRHQQEVK-----RQLAPAPL---KEQA
NEK1_Hsap -GQL-VIP-LDE--LTLDTSFS-TTER----------------------HTVGEVIKLGP
NEK5_Hsap -APQTLLQMMAV--ADITSTCP-TGPD------------------------NGQVIVIEG
NEK3_Hsap -VPNTALTALEN--ASILTSSL-TAED----------------------DRGGSVIKYSK
NEK1_Mmus -GQL-VIP-LDA--VTLDTSFS-ATEK----------------------HTVGEVIKLDS
NEK3_Mmus -GPSSNVEALEK--ASILTSSF-TAED----------------------DRGGSVIKYEE
NEK5_Mmus -APHTLLRIMAM--ADVTSTCP-TMPD------------------------DGQVIVMEG
Nek3_Ddis -SSSS---LPKS--SLKSDSLCTSPPRFSNTTGSSGGIGVSGNGNSNVNSTVLNRSVS-S
AqueK176_Aque DMPPSLAE--------GDATSA-TVNE----------------------KTTSDVV-FE-
GK072_Glam DIPESASSAFKYNSDPILSHIF--------------------------------------
GK270_Glam -KDARERELMEA--HNKVQRQK---------------------------EEQERRIRE-A
NEK1_Hsap NGSPRRAWGKS-------------PTDSVL------------------KILGE---AELQ
NEK5_Hsap IPGNRKQWRHE-------------APGTLM------------------SVLAA---AHLT
NEK3_Hsap N-TTRKQWLKE-------------TPDTLL------------------NILKN---ADLS
NEK1_Mmus NGSPRKVWGKN-------------PTDSVL------------------KILGE---AELQ
NEK3_Mmus N--ARRQWVRE-------------PPEALL------------------SMLKD---ADLS
NEK5_Mmus SVENGKQWWLD-------------VPGTPC------------------ALAAE---CACS
Nek3_Ddis LSIQHKPTNSGSSSISSSSSGNNSNSNTTTNNNTTSTTPIRPGLKSTKSMLELSTPTSIS
AqueK176_Aque RPKPRPAWGVA-------------DTPLEI------------------PAMPT---QDIS
GK072_Glam ---------------------------SQL------------------VLLVD---HDST
GK270_Glam KEKQRAEWEKR-------------NREYEK------------------QMEEK---RKAA
NEK1_Hsap LQ-----------------TELL--EN----TTIRSEISPEGEKYKPLITGEKKVQCISH
NEK5_Hsap SS-----------------S--F--SA----D-------------EE-------------
NEK3_Hsap LA-----------------FQTY--TI-----------------YRP-------------
NEK1_Mmus LQ-----------------TELL--EN----TSFKSEVYAEEENYKPLLTEEENLQCISK
NEK3_Mmus QA-----------------FQTY--TI-----------------YRP-------------
NEK5_Mmus -G-----------------S--L--SA----S-------------K--------------
Nek3_Ddis TSNKSTTTTPTSSRSNTPSTGRLSLTT-----S----------IPRP-------------
AqueK176_Aque IC-----------------PEET--AILFENKSRPPKEDAGEIGKTRVISLE--------
GK072_Glam VA-----------------SQLV--SI-----------------VRL-------------
GK270_Glam QA-----------------AEDR--EK----ER----------LFRI-------------
NEK1_Hsap EINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDDLETEILQEPS---GTNKDESL
NEK5_Hsap -------------------------FA---MGTLKQWLPKEED-----------------
NEK3_Hsap -------------------------GS---EGFLKGPLSEETEA----------------
NEK1_Mmus EINPSATVDS-TETKSPKFTEVSPQMS---EGNVEEPDDLETEVLQEPS---STHTDGSL
NEK3_Mmus -------------------------GA---EGFLKGPLSEDT-A----------------
NEK5_Mmus -------------------------GE---TVMIKPQLPKE-D-----------------
Nek3_Ddis ------------------------PS---SNGSNTGSSSSTTTTPTK-ISTTSSSS----
AqueK176_Aque ---------------SHHYS------N---EGERQRSPGEEEKGD----DKT----DG--
GK072_Glam -----------------------------------------TYS----------------
GK270_Glam ------------------------S---------NGPANAGSEA-----NPSKGGMESLL
NEK1_Hsap PCTITDV--------WISEEKETKETQSADRITIQENEVSEDGVSSTVDQLSDIHIEPGT
NEK5_Hsap --------------------------------------------EGKVE-----------
NEK3_Hsap --------------------------------------------SDSVDG----------
NEK1_Mmus PPVLNDV--------WTREKEAAKETELEDKVAVQQSEVCEDRIPGNVDQSCKDQRDPAV
NEK3_Mmus --------------------------------------------SDSVDG----------
NEK5_Mmus --------------------------------------------QEKVE-----------
Nek3_Ddis -------SLNKLTTPIK-------------------SSTTTSTTAST-------------
AqueK176_Aque -----GT--------WINEVELAKPQPLTSR----ENIVCNDE------GSIGKERSVVS
GK072_Glam --------------------------------------------FQDVD-----------
GK270_Glam PPKIMDPGVQNRNDPRNHEERTEQQRKLEEQRDAMRRMIAERRREQE-------------
NEK1_Hsap NDSQHSKCDVDKSVQPEPFFHKVVHSEHLNL---VPQ-----VQSVQCSPEESFAFRSHS
NEK5_Hsap ------------------------------------------------------------
NEK3_Hsap ------------------------------------------------------------
NEK1_Mmus DDSPQSGCDVEKSVQPESIFQKVVHSKDLNL-----------VQAVHCSPEEPIPIRSHS
NEK3_Mmus ------------------------------------------------------------
NEK5_Mmus ------------------------------------------------------------
Nek3_Ddis -----NSQTIKKSITPIKVTSQQVDSTISNI---KNN----IVIGNSVSTKTNISVISHL
AqueK176_Aque LNVEE---EGEGVRMKEPLFDKVLKDREEKSIKSLPQAEETIVSDIECEEEEELEEEQGK
GK072_Glam ------------------------------------------------------------
GK270_Glam -----LK-RGEQ----------RAQPPVDEI---K-------------------------
NEK1_Hsap HL-----------PPKNKNKNSLLIGLSTGLFDANNPKM---LRTCSLPDLSKLFRTLMD
NEK5_Hsap ------------------------------------------------------------
NEK3_Hsap ------------------------------------------------------------
NEK1_Mmus DS-----------PPKTKSKNSLLIGLSTGLFDANNPKM---LRTCSLPDLSKLFRTLMD
NEK3_Mmus ------------------------------------------------------------
NEK5_Mmus ------------------------------------------------------------
Nek3_Ddis SP-----------SIKPLPTQSIITQLPTSASTASTASTTNTTLTSGTNTMTTKKRTDFK
AqueK176_Aque EKEREEDEVEDEESEEIFEPDGLSRSLKSGHYDTN-YTI---LRTCSLPDLRLTTP-TIK
GK072_Glam --------------------------------------M---LRDITLLDIPPHFNDIYK
GK270_Glam ------------------------------------------------ENLSAKGRRLCD
NEK1_Hsap VPTVGDV-RQDNLEIDEIEDENIKE-GPSDSEDIV----FEE------------------
NEK5_Hsap --------MVSGIEV---DEEQL-E-PRSDDDDTN----FEE------------------
NEK3_Hsap --------GHDSVIL---DPERL-E-PGLDEEDTD----FEE------------------
NEK1_Mmus VPTVGDV-HQDSLEIDELEDEPIKE-GPSDSEDTV----FEE------------------
NEK3_Mmus --------DLDSVML---DPERF-E-PRLDEEDTD----FEE------------------
NEK5_Mmus --------IATGIMV---DDEQL-E-PGSDEDDIK----FEE------------------
Nek3_Ddis LDDLGHRSKLNSVKLSSKSSSPIKT-SSSSSSSS----SSSS------------------
AqueK176_Aque VELTTPT-NQSQIPCT-RSDVNIKEAAPAQKEDTDT--VFDTPLSSSIDLDTPTSVADIA
GK072_Glam S----------------------KT-AWTDNSCTT----WDR------------------
GK270_Glam VPSV-----------QEPAVQPT-----GQTDDKNALACLDE------------------
. . .
NEK1_Hsap ----------TDTDLQ-------ELQASMEQLLRE--QPGEEYS--EEEESVLKNSDVEP
NEK5_Hsap ----------SEDELR------DEVVEYLEKLA-T--FKGEEKT--EEASSTSKDSRKSR
NEK3_Hsap ----------EDDN-P------D-WVSELKKRA-G--W----------------------
NEK1_Mmus ----------TDTDLQ-------ELQASMEQLLRE--QPGDEYS--EEEESVLKSSDVEQ
NEK3_Mmus ----------DNEN-P------D-WVSELKKHV-G--YG---------------------
NEK5_Mmus ----------SEDELR------SEIIESLEKLA-A--ST--EEA--EQAPSSSKNAEEPG
Nek3_Ddis ----------SITDKK-------SINRVKLNNLKE--KNKEIINNIKISSTIPKPSNINS
AqueK176_Aque TPNDTESGSSSLTDVEDNDRGYEEMIKTLRDLYNKGGTPSPK--PVSHNTSTPNPGHIST
GK072_Glam ------------------------------------------------------------
GK270_Glam ----------KDS-----------------------------------------DSDFED
NEK1_Hsap TA---------------------------------NGTDVADEDDNPSSESALNEEWHSD
NEK5_Hsap ER---------------------------------EGIS---------------------
NEK3_Hsap ------------------------------------------------------------
NEK1_Mmus TA---------------------------------RGTDAPDEEDNPSSESALNEEWHSD
NEK3_Mmus -----------------------------------------------------------D
NEK5_Mmus EK---------------------------------EKT----------------------
Nek3_Ddis SSSSAFSDLNSSGSSSLNNSLTSSSSSIITNQNNQNNQNNQNNQNNQNNLKIINELILQN
AqueK176_Aque TENE-------------------------------EGTEREEE-EGACHCSLVEEDWESS
GK072_Glam ------------------------------------------------------------
GK270_Glam PY---------------------------------FNPNAPDGNGGPG---SLDKAEKAA
NEK1_Hsap NSDGEIA----------SECEC-DSVFNHLEELRLHLEQEMGFEKFFEV-YEKIKAIHED
NEK5_Hsap --------------------------MQKSEELREGLEN------ISTTSNDHICITDED
NEK3_Hsap ------------------------------------------------------------
NEK1_Mmus NSDAETT----------SECEY-DSVFNHLEELRLHLEQEMGFEKFFEV-YEKVKAIHED
NEK3_Mmus GP----------------------------------------------------------
NEK5_Mmus ------------------------------------------------------------
Nek3_Ddis NLNNSIS----------KENLDDKRLHSRANALRHFCSSIFGEDKFKET-YNLLKSQSPS
AqueK176_Aque DDEFTDGSDGVDRCGSSNKGEGQGRIFDKLEETRNRLEEKLGLDNLLEA-YTVVKEFQDR
GK072_Glam ------------------------------------------------------------
GK270_Glam NMMKMLR----------AETTE-ESISQRMERLRILLEGELGLTNFVKA-YQYIRTNTEQ
NEK1_Hsap E-DENIEICS------------KIVQNILGNEHQHLYAKILHLVMADGAY----------
NEK5_Hsap Q-GT-------------------------------------------STT----------
NEK3_Hsap -------------------------------------------------Q----------
NEK1_Mmus E-DENIEICS------------TIVENILGNEHQHLYAKILHLVMADGAY----------
NEK3_Mmus -----------------------------------------------GGQ----------
NEK5_Mmus ------------------------------------------------NL----------
Nek3_Ddis T-SNN-EIVDIASI-------ENQLSQLIGDKIY-YLKYLQQLIYC--------------
AqueK176_Aque ECDEDTNVLSSDTVTAQDGFPLATLTSIIGEEHSHCFPSLIHLVISDSAYFELNAQSTNQ
GK072_Glam ----ETELLS------------WIFERIAGEKGDACLGLCRLLVSA--------------
GK270_Glam G-GED-DLNQ------------NVIVGIIGETNVGFINTIVSLIYCEDR-----------
NEK1_Hsap -------------QEDNDE
NEK5_Hsap -------------SQNIQV
NEK3_Hsap --------------GLCDR
NEK1_Mmus -------------QEDNDE
NEK3_Mmus -------------LLGERA
NEK5_Mmus -------------PVKKLQ
Nek3_Ddis ---------------ESQI
AqueK176_Aque KSSSETLLSMATGSLVLES
GK072_Glam ---------------DDYS
GK270_Glam --------------FNTVR