jkk-1_Cele      IHIISLLGSGSCGVVE-----------SATTMY-KNDNKENLKRILRDVRIM-SMCNSPF
mek-1_Cele      LQFVEDIGHGSCGTVTKCRYK--SVIMAVKTMP-RTSNSYEMSRILMDLDVICLSFDCPY
hep_Dmel        LKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMR-RTGNAEENKRILMDLDVVLKSHDCKY
MAP2K7_Mmus     LENLGEMGSGTCGQVWKMRFRKTGHIIAVKQMR-RSGNKEENKRILMDLDVVLKSHDCPY
MAP2K7_Hsap     LENLGEMGSGTCGQVWKMRFRKTGHVIAVKQMR-RSGNKEENKRILMDLDVVLKSHDCPY
MKK7_Spur       LESIGELGFGSCGHVIRMRHKESGTILAVKQMR-RSGNKEENKRILMDLDVVLKSHNCPF
AqueK248_Aque   MLDVKRVGSGISGEVYRMVHNPSSIAIAAKKMLWQHDTWEEQRRVLMDLEVM-NSQHSPF
                :  :  :* * .* *            :.. *  : ..  :  *:* *: ::    .. :

jkk-1_Cele      IVTSYGYFMFDSSVKICMQIMSACCEKLLRRIYHSKLDFFPEFVAGHIVYSAISALDYLK
mek-1_Cele      IVRCFGYFITNFDVRVCMECMATCLDRLLIRIKQ----PIPERIIGKLSVSIIKALHYLK
hep_Dmel        IVKCLGCFVRDPDVWICMELMSMCFDKLLKLSKK----PVPEQILGKVTVATVNALSYLK
MAP2K7_Mmus     IVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQG----PIPERILGKMTVAIVKALYYLK
MAP2K7_Hsap     IVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQG----PIPERILGKMTVAIVKALYYLK
MKK7_Spur       IVQCLGAIVTPSEVWICMEQMATCLDKLIKKLRE----PVPEQIIGKMVVAIVNALNYLK
AqueK248_Aque   IVEYYGSAIVKNEVWVFMELMATCLDRLLKRLKG----PIPERIIGKMCVSIVKALDYLK
                **   *  :   .* : *: *. * ::*           .** : *::  : :.** ***

jkk-1_Cele      EKHSIIHRDIKPSNILFDDSGNVKLCDFGISGFMTDSMAHSKSAGCPPYMAPERLTIET-
mek-1_Cele      TKHQIMHRDVKPSNILLDWSGVIKLCDFGIAGRLIESRAHSKQAGCPLYMGPERLDPNN-
hep_Dmel        DKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERIDP---
MAP2K7_Mmus     EKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDP
MAP2K7_Hsap     EKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDP
MKK7_Spur       EKHGVMHRDVKPSNMLLDEKGVVKLCDFGISGRLVDSKARTRSAGCAAYMAPERIDPPDP
AqueK248_Aque   RAHKVIHRDVKPSNILIDVNGNVKLCDFGISGRLVDSKAFTRGAGAAAYMAPERINMSHD
                  * ::***:****:*:*  * :*******:* : :* * :: **.. **.***:

jkk-1_Cele      -NSKYDVRSDVWSLGITV-------YQLVTGLYPFPLN--DMEFTTLTIIANLNLPSPSL
mek-1_Cele      -FDSYDIRSDVWSFGVTL-------VELATGQYPYAG----TEFDMMSKILN--DEPPRL
hep_Dmel        KKPKYDIRADVWSLGITL-------VELATARSPYEGC--NTDFEVLTKVLD--SEPPCL
MAP2K7_Mmus     TKPDYDIRADVWSLGISLQCLSPSQVELATGQFPYKNC--KTDFEVLTKVLQ--EEPPLL
MAP2K7_Hsap     TKPDYDIRADVWSLGISLPCPSPSQVELATGQFPYKNC--KTDFEVLTKVLQ--EEPPLL
MKK7_Spur       NNPDYDVRADVWSLG---------------------------------------------
AqueK248_Aque   -SKGYDVRADVWSLGISL-------VEMATGSAPYKFNEFSSEFDLLTHIVQ--APPPLL
                    **:*:****:*

jkk-1_Cele      REETKRSFSPLFIEFLDLCLRKDVRERPEYRQLMKHDFY
mek-1_Cele      DP---AKFSPDFCQLVESCLQRDPTMRPNYDMLLQHPFV
hep_Dmel        PYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLAQPFI
MAP2K7_Mmus     PGH--MGFSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFI
MAP2K7_Hsap     PGH--MGFSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFI
MKK7_Spur       --------------------------------------I
AqueK248_Aque   DE---DKFSPNFYDFVAQCLCKDVDERPQYDKLLLHPLI