JNK3_Hsap MSLHFLYYCSEPT---LDVK----------------------------------------
JNK2_Hsap M-----------------------------------------------------------
JNK1_Hsap M-----------------------------------------------------------
bsk_Dmel M-----------------------------------------------------------
JNK3_Mmus MSLHFLYYCSEPT---LDVK----------------------------------------
JNK2_Mmus M-----------------------------------------------------------
JNK1_Mmus M-----------------------------------------------------------
jnk-1_Cele MEERLSTTSSYPSHPGRSVEEDHNTLLASSSISSIIRGTRGHLNNFIESVGNWLVPSSSG
C49C3.10_Cele MQT---------------------------------------------------------
T07A9.3_Cele MEVDLPV-----------------------------------------------------
Y51B9A.9_Cele M-----------------------------------------------------------
ZC416.4_Cele MNLP--------------------------------------------------------
JNK_Spur MCEFDLHV-----QPIRSRQ-----------------------------------MAGT-
AqueK127_Aque M-----------------------------------------------------------
*
JNK3_Hsap -------IAFCQGFDKQVDVSYIAKHYN----------MSKSKVDNQFYSVEV------G
JNK2_Hsap ---------------------------------------SDSKCDSQFYSVQV------A
JNK1_Hsap ---------------------------------------SRSKRDNNFYSVEI------G
bsk_Dmel ---------------------------------------TTA--QHQHYTVEV------G
JNK3_Mmus -------IAFCQGFDKHVDVSSIAKHYN----------MSKSKVDNQFYSVEV------G
JNK2_Mmus ---------------------------------------SDSKSDGQFYSVQV------A
JNK1_Mmus ---------------------------------------SRSKRDNNFYSVEI------G
jnk-1_Cele RDDDAVSLDSCQSVYS-----PVRHHINSGTGGGILMEPSSIHVPENYYSVTI------G
C49C3.10_Cele -----------------------------------------------YHEFQQ-----PN
T07A9.3_Cele ---------------------------------------HNEYDASRFHQVTIRDPIAGA
Y51B9A.9_Cele -----------------------------------------------FRQ-EI-----LN
ZC416.4_Cele ---------------------------------------------SKFHQVTITDPIAGA
JNK_Spur ------KLNHHQ-----------PNHHQ----------FNYHQLNSQFYHVTV------G
AqueK127_Aque ---------------------------------------A------DFYTTQV------G
.
JNK3_Hsap DSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRP--FQNQTHAKRAYREL
JNK2_Hsap DSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP--FQNQTHAKRAYREL
JNK1_Hsap DSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP--FQNQTHAKRAYREL
bsk_Dmel DTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRP--FQNVTHAKRAYREF
JNK3_Mmus DSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRP--FQNQTHAKRAYREL
JNK2_Mmus DSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP--FQNQTHAKRAYREL
JNK1_Mmus DSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP--FQNQTHAKRAYREL
jnk-1_Cele EAQMVVLKRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRP--FQNVTHAKRAYREL
C49C3.10_Cele GTFFTVPVRYVNVQPFQFD-KPFVVHAFDQVLGRPVVIKKVMLPDSLHDRQPWRRAQREL
T07A9.3_Cele DSTFTIPTRYVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQP--FVMTMSAKRAYREF
Y51B9A.9_Cele EVLFIVPNRYVDLLPSQFG-NAMEVIAFDQISERRVVIKKVVLPENFDNWQHWRRAQREL
ZC416.4_Cele GITFTIPTRYVNLKFLNVGAQGIVVMADDLVTTQRVAIKKMQQP--FLLTMSARRAYREF
JNK_Spur DTHFQILKRYKNLKSVGSGAQGLVVAAYDVLTNQSVAIKKLSRP--FQNVTHAKRAYREY
AqueK127_Aque DTLFTIPRRYQDLKPLGHGAQGVVCSAKDSVRGERIAIKKLVKP--FQNETYAKRAFREL
: : ** :: . : * * : :.:**: * : :** **
JNK3_Hsap VLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ---MELDHERMSYL
JNK2_Hsap VLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH---MELDHERMSYL
JNK1_Hsap VLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ---MELDHERMSYL
bsk_Dmel KLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQ---MDLDHDRMSYL
JNK3_Mmus VLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ---MELDHERMSYL
JNK2_Mmus VLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH---MELDHERMSYL
JNK1_Mmus VLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ---MELDHERMSYL
jnk-1_Cele KLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQ---MDLDHERLSYL
C49C3.10_Cele NCMLNIEDDNVVKMYSTFTPAENPLKMTEFYIVREYMHGTMKNLSASTFNEGGHRTVKSI
T07A9.3_Cele ILLTTIKHPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVIH--RLRLDHKTLSFF
Y51B9A.9_Cele FCTLHIQEENFVKMYSIYTWVETVEEMREFYTVREYMDWNLRNFILSTPEKLDHKVIKSI
ZC416.4_Cele ILLTTLKHPNIIRLLNAFTPDTSLSSFQEVYLVMEFMTHNLHEVIH--RLRLDHETLSFL
JNK_Spur ILMKLCNHKNIIGLLNVFTPQRTFDDFADIYLVMELMDASLVQVVQ---MDLDHERISYL
AqueK127_Aque KLMKMVNHKNVIGLLNLFSPAHSIEDFEDVYIVMELMDANLCRVIG---IELDHDRMSYL
:. *.: : . :: . : :.* * * * .: .. .* :. :
JNK3_Hsap LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA--GTSFMMTPYVVTR
JNK2_Hsap LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA--CTNFMMTPYVVTR
JNK1_Hsap LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA--GTSFMMTPYVVTR
bsk_Dmel LYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTA--GTTFMMTPYVVTR
JNK3_Mmus LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA--GTSFMMTPYVVTR
JNK2_Mmus LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA--CTNFMMTPYVVTR
JNK1_Mmus LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA--GTSFMMTPYVVTR
jnk-1_Cele LYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTA--IEAFMMTPYVVTR
C49C3.10_Cele FFDICRGVQYLHAMRISHRDLKPENILMNQEGDVKLCDFGHSNKE--D-PTSNTPYIVQR
T07A9.3_Cele VYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVDTSMRMSDYVVTR
Y51B9A.9_Cele FFDVCLAVQYMHSIRVGHRDLKPENVLINYEAIAKISGFAHANRE--D-PFVNTPYIVQR
ZC416.4_Cele VYQSLCAIKHLHNLGFIHRDLKPSNIVVNERCVLKVLDFGLARRR--NVDMRMSDYVGTR
JNK_Spur LYQMLCGIKHLHSAGIIHRDLKPSNIVVKTDCSLKILDFGLARTA--STSFMMTPYVVTR
AqueK127_Aque LYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLARAA--DKAFMMTPYVVTR
.:: .::::* . ******.*:::. *: .*. :. : *: *
JNK3_Hsap YYRAPEVILGM--GYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPE
JNK2_Hsap YYRAPEVILGM--GYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAE
JNK1_Hsap YYRAPEVILGM--GYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPE
bsk_Dmel YYRAPEVILGM--GYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPS
JNK3_Mmus YYRAPEVILGM--GYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPE
JNK2_Mmus YYRAPEVILGM--GYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAE
JNK1_Mmus YYRAPEVILGM--GYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPE
jnk-1_Cele YYRAPEVILGM--GYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRS
C49C3.10_Cele FYRAPEIICETTDNNKTNVDIWSLGCILAELLTGHVLFRGKDHIDQFILMVQFLGNAGPS
T07A9.3_Cele YYRAPEVILGL--PYSEKVDIWSVGCIFAEMINHTVLFPGKDRIDQWTKIYSVLGTPDDH
Y51B9A.9_Cele FYRAPEILCETMDNNKPSVDIWSLGCILAELLTGKILFTGQTQIDQFFQIVRFLGNPDLS
ZC416.4_Cele YYRAPEVILGL--NYSEKVDIWSVGCILAEMINHTVLFPGKDIRDQWTQISSVLRTPDDH
JNK_Spur YYRAPEVILGM--GYKENVDIWSIGCIFGEMIRGQVMFPGSDHIDQWNKIADLLGTPTDI
AqueK127_Aque YYRAPEVIVGM--KYKENVDIWSVGCIFAEIVRGDILLPGRDYIDQWNKVTQILGTPPQE
:*****:: . .**:**:***:.*:: ::: * **: : * ..
JNK3_Hsap FMKKLQPTVRNYVE--NRPK--YA-GLTFPKLFPDSLFPA-DSE--HNKLKASQARDLLS
JNK2_Hsap FMKKLQPTVRNYVE--NRPK--YP-GIKFEELFPDWIFPS-ESE--RDKIKTSQARDLLS
JNK1_Hsap FMKKLQPTVRTYVE--NRPK--YA-GYSFEKLFPDVLFPA-DSE--HNKLKASQARDLLS
bsk_Dmel FMQRLQPTVRNYVE--NRPR--YT-GYSFDRLFPDGLFPN-DNN-QNSRRKASDARNLLS
JNK3_Mmus FMKKLQPTVRNYVE--NRPK--YA-GLTFPKLFPDSLFPA-DSE--HNKLKASQARDLLS
JNK2_Mmus FMKKLQPTVRNYVE--NRPK--YP-GIKFEELFPDWIFPS-ESE--RDKIKTSQARDLLS
JNK1_Mmus FMKKLQPTVRTYVE--NRPK--YA-GYSFEKLFPDVLFPA-DSE--HNKLKASQARDLLS
jnk-1_Cele FLERLQPTVRNYVE--NRPR--YQ-ATPFEVLFSDNMFPM-TAD--SSRLTGAQARDLLS
C49C3.10_Cele FYSQMNEHARNFLLRYNLDQ--YQAPINFYSRFPDTVFQG-VLQ--FEPKECDMSRDLLF
T07A9.3_Cele FISQLGQSAAMYVR--SLPR--HQ-ARAFSEIVPDTNFLP-ETENPRVHLTPHVARDLLF
Y51B9A.9_Cele FYMQMPDSARTFFL--GLPMNQYQKPTNIHEHFPNSLFLD-TMI--SEPIDCDLARDLLF
ZC416.4_Cele FINQLEPIGAVYVR--SLPQ--HL-ARAFNEIVPDSNFLP-ETENPKDHLTLHMARDLLF
JNK_Spur FLSRLQPMVKQYVE--NRTK--CP-GYSFEMLFPDELFYQAESSTEKTKLCVAQARNLLS
AqueK127_Aque FFKQLQPSVRMYCE--SQPR--HK-GKSWNELFPDDVFPN-DSK--EDAHKTRLAVDLLT
* :: : . ..: * : :**
JNK3_Hsap KMLVIDPAKRISVDDALQHPYIN-VWYDPA----EVEAPPPQ-IYDKQLD----------
JNK2_Hsap KMLVIDPDKRISVDEALRHPYIT-VWYDPA----EAEAPPPQ-IYDAQLE----------
JNK1_Hsap KMLVIDASKRISVDEALQHPYIN-VWYDPS----EAEAPPPK-IPDKQLD----------
bsk_Dmel KMLVIDPEQRISVDEALKHEYIN-VWYDAE----EVDAPAPE-PYDHSVD----------
JNK3_Mmus KMLVIDPAKRISVDDALQHPYIN-VWYDPA----EVEAPPPQ-IYDKQLD----------
JNK2_Mmus KMLVIDPDKRISVDEALRHPYIT-VWYDPA----EAEAPPPQ-IYDAQLE----------
JNK1_Mmus KMLVIDASKRISVDEALQHPYIN-VWYDPS----EAEAPPPK-IPDKQLD----------
jnk-1_Cele RMLVIDPERRISVDDALRHPYVN-VWFDEI----EVYAPPPL-PYDHNMD----------
C49C3.10_Cele RMLVINPDDRLNIQMVLSHPYLREIWGEIV---AEDVIPEPQ-PPNELLRF---------
T07A9.3_Cele NMLKINPEERYSVEDALNHPYVK-LWFKDD----EVNAPASENRYDQEI-----------
Y51B9A.9_Cele RMLVINPDDRIDIQKILVHPYLEEVWSNIVIDNKIEEKYPPI-ALRRF------------
ZC416.4_Cele NMLKINPEERYSVEDALNHPYTM-----DD----EVNAPASE-IPDDEVN----------
JNK_Spur KMLIVDPEQRISVDEALQHPYIN-VWFDPG----EVYGPPPI-PYDHSIDDGGDHILEEW
AqueK127_Aque KMLQIEPTRRVTVDEALKHPYVS-IWYDPS----EADAPPPP-KYDHCLD----------
.** ::. * :: * * * .
JNK3_Hsap -------------ERE-HTIEEWKELIYKEVMNS-----------EEKTKNGV-------
JNK2_Hsap -------------ERE-HAIEEWKELIYKEVMDW-----------EERSKNGV-------
JNK1_Hsap -------------ERE-HTIEEWKELIYKEVMDL-----------EERTKNGV-------
bsk_Dmel -------------ERE-HTVEQWKELIYEEVMDY-----------EAHNTNN--------
JNK3_Mmus -------------ERE-HTIEEWKELIYKEVMNS-----------EEKTKNGV-------
JNK2_Mmus -------------ERE-HAIEEWKELIYKEVMDW-----------EERSKNGV-------
JNK1_Mmus -------------ERE-HTIEEWKELIYKEVMDL-----------EERTKNGV-------
jnk-1_Cele -------------V-E-QNVDSWREHIFRELTDY-----------ARTH-----------
C49C3.10_Cele -----------FDFQPYSSPLDMREEIFQKIKNF-----------GNQYN----------
T07A9.3_Cele ------------DFAD-KTLIEWKELIFNEVQRY-----------QADHD----------
Y51B9A.9_Cele -----------FEFQAFSPPRQMKDEIFSTLTEF-----------GQQYN----------
ZC416.4_Cele ------------DIDD-WTLIEWKRLIFNEVQGY-----------QTDHD----------
JNK_Spur KDGTSHPIEEEKDERE-HTLEQWKDEREHTLEQWKGKLHYSYSESREHFDMFMLVFQAFE
AqueK127_Aque -------------EKN-IPLAQWKKLIYEEVISF-----------DERR-----------
. : :
JNK3_Hsap -----------VKGQPSPSGAAV-NSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASA
JNK2_Hsap -----------VKDQPSD--AAV-SSNATPSQSSSINDISSMSTEQTLASDTDSSLDAST
JNK1_Hsap -----------IRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAA
bsk_Dmel ------------------------------------------------------------
JNK3_Mmus -----------VKGQPSPSGAAV-NSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASA
JNK2_Mmus ------------KDQPSD--AAV-SSKATPSQSSSINDISSMSTEHTLASDTDSSLDAST
JNK1_Mmus -----------IRGQPSPLA----------------------------------------
jnk-1_Cele ------------------------------------------------------------
C49C3.10_Cele --------------------------------------I---------M-----------
T07A9.3_Cele ------------------------------------------------------------
Y51B9A.9_Cele --------------------------------------I---------F-----------
ZC416.4_Cele ------------------------------------------------------------
JNK_Spur HNSSYWIIILAIANTPKWSGVV-RLFN---VILSHLQDLHASSVRCMDVARTHFMYYACA
AqueK127_Aque ------------------------------------------------------------
JNK3_Hsap -GPLGCCR
JNK2_Hsap -GPLEGCR
JNK1_Hsap -GPLGCCR
bsk_Dmel -----RTR
JNK3_Mmus -GPLGCCR
JNK2_Mmus -GPLEGCR
JNK1_Mmus ----QVQQ
jnk-1_Cele ----DIYS
C49C3.10_Cele ---NESKN
T07A9.3_Cele ----IFTG
Y51B9A.9_Cele ---NNSRN
ZC416.4_Cele ----IFNE
JNK_Spur IYVSESLF
AqueK127_Aque ----DAKR