Protein (view, download) , Domain (view, download)
GCN2_Hsap        -FEELQLLGKG-AFGA-VIKV-Q---------------------NKLD-GCCYAVK--RI
GCN2~b_Hsap      -VHKGKCIGSDEQLGK-LVYN-ALETATGGFVLLYEWVLQW--QKKMG-PFLTSQE--KE
Gcn2_Dmel        -IQRGCCVGHS-QRGC-IAYT-G---------------------IDMHCGQLLYIT--EW
Gcn2~b_Dmel      -FEVLMYLGKG-AFGD-VLKV-R---------------------NILD-NREYAIK--RI
GCN2_Mmus        -FEELQLLGKG-AFGA-VIKV-Q---------------------NKLD-GCCYAVK--RI
GCN2~b_Mmus      -VHKGRCVGSDEQLGK-VVYN-ALETATGSFVLLHEWVLQW---QKMG-PCLTSQE--KE
GCN2_Scer        -FEEIAVLGQG-AFGQ-VVKA-R---------------------NALD-SRYYAIK--KI
Y81G3A.3_Cele    -NVIIRVLGRG-GFGD-VVLV-R---------------------NKMD-STDYAIK--RI
DDB0216407_Ddis  -FEEIQLLGRG-GFGQ-VVKV-R---------------------NKLD-GRYYAIK--KI
IfkB_Ddis        -EQSSSDSENG-ENGM-KSRIIE---------------------NASD-S----------
11434_Tthe       -FRVIDELGRG-GFGR-VYKV-Q---------------------SMVE-EKIYAIK--KI
18670_Tthe       -FEEVEQIGKG-GFGQ-VYKV-K---------------------NRLD-SLNYAVK--KI
21870_Tthe       -FEEIQVLGQG-AFGQ-VVKV-R---------------------NKLD-GRYYAIK--KI
GCN2_Spur        -FEFLAFLGKG-GFGN-VIKV-R---------------------NKLD-GNLYAIK--KI
GCN2~b_Spur      -VHKGILLGSN-PEGS-SVYA-GMDAHSGDLLTIREWVIKWKQG--KG-RKPLPDE--EE
CC1G_02807_Ccin  -WEELELLGKG-AFGS-VVKA-R---------------------NKVD-NRVYAVK--KV
AqueK195_Aque    -FEVLEVLGKG-GFGD-VIKV-R---------------------NYLD-SRLYAIK--KV
AqueK195~b_Aque  NILRGKLLGDS-SHGYYSVYC-GMEVDSGSLVCIYEWIIPCKTQKKAD-TRRSRQAGGAG
AqueK194_Aque    -FEVLEVLGKG-GFGD-VIKV-R---------------------NYLD-SRLYAIK--KV
AqueK194~b_Aque  NILRGKLLGDS-SHGYYSVYC-GMEVDTGSLVCVYEWIIPCKTQKKAD-TRRSRQA-GAG
AqueK193_Aque    -FEEIKLLGKG-AFGE-VYHV-K---------------------HNLD-KKEYAMK--II
PEKc_Smoe        -FEELCLLGKG-GFGH-VVLC-K---------------------NKLD-GRRYAMK--KV
PEKa_Smoe        -FEELCLLGKG-GFGH-VVLC-K---------------------NKLD-GRRYAMK--KV
GK065_Glam       -FVELYQLGKG-GYGE-VVCA-N---------------------RLME-NQKYAVK--KV
                           .   *

GCN2_Hsap        PIN-------------------------PA--SR------------QFRRIKGEVTLLSR
GCN2~b_Hsap      KID-------------------------KC--------------KKQIQGTETEFNSLVK
Gcn2_Dmel        NIKYSQLEQPCIGGGKCHWSSESKCMGSHR--V-----------DEVMASIEKQVSSLSQ
Gcn2~b_Dmel      PLP-------------------------AR--SR-----------QLYKKMTREVELLSR
GCN2_Mmus        PIN-------------------------PA--SR------------HFRRIKGEVTLLSR
GCN2~b_Mmus      KID-------------------------KC--------------KRQIQGAETEFSSLVK
GCN2_Scer        RHT-----------------------------EE------------KLSTILSEVMLLAS
Y81G3A.3_Cele    PLN-------------------------AK--SD-----------KLNRKIAKEAKFFAK
DDB0216407_Ddis  KLD-------------------------SN--QS------------LNRRILREVITLSR
IfkB_Ddis        ------------------------------------------------------------
11434_Tthe       AVP-------------------------YDGFSN-----------PKEHKYFREVKSIMS
18670_Tthe       KLD-------------------------IN--QK-----------ELTKKTLKEVKLLSI
21870_Tthe       KIR-------------------------KG---------------QNIEKLMREVTLLSR
GCN2_Spur        LLN-------------------------PK--SR-----------ELNKKITREVKLLSR
GCN2~b_Spur      DAE-------------------------AC--------------LKQCASVEQELLSLLR
CC1G_02807_Ccin  RLK-------------------------AV--Q-------------KDDKIMREVNALSR
AqueK195_Aque    RLT-------------------------GG--SK------------MMTKLTREVELLSQ
AqueK195~b_Aque  SVG-------------------------RS--E-----------GNLVASIRQEYDSFSE
AqueK194_Aque    RLT-------------------------GG--SK------------MMTKLTREVELLSQ
AqueK194~b_Aque  SVG-------------------------RS--E-----------GNLVASIRQEYDSFSE
AqueK193_Aque    PAN------------------------------------------KINQKDLREVLALSD
PEKc_Smoe        KLK-------------------------DE---------------NPSDKILREVATLSR
PEKa_Smoe        KLK-------------------------DE---------------NPSDKILREVATLSR
GK065_Glam       VID-------------------------RR--DFHAKTESVGGFLQYIKSIMNEVRILSR


GCN2_Hsap        --LHHENIVRYYNAWIERHERPAGPGTP------------------PPD--------SG-
GCN2~b_Hsap      --LSHPNVVRYLAMNLKEQ-----------------------------------------
Gcn2_Dmel        --LQHKNLVSYECVLCIKRK----------------------------------------
Gcn2~b_Dmel      --LNHENVVRYFNSWIESV-----------------------------------------
GCN2_Mmus        --LHHENIVRYYNAWIERHERPAVPGTP------------------PPD--------CT-
GCN2~b_Mmus      --LSHPNIVRYFAMNSREE-----------------------------------------
GCN2_Scer        --LNHQYVVRYYAAWLEED-----------------------------------------
Y81G3A.3_Cele    --LNHPNMVRYYYAWAEDLIPIVEETSD------------------DDSSLGAVPIPGKE
DDB0216407_Ddis  --LHHQHVVRYYQAWIESAESLSLTNDNSDDDDDDDDEFESGSESEESQ--------SE-
IfkB_Ddis        ----------Y-------------SDDDNNNNNDSNNNYHSDNE---SD--------SF-
11434_Tthe       --LNHINIVRYHTSWWENCDDEMVNQVN------------------EFL--------QT-
18670_Tthe       --LQHNHIVRYYQAWLEKPDEKTLQEFE------------------NSE--------EE-
21870_Tthe       --LHHRHVLRYYQAWLEESNQSEEE---------------------E-S--------MG-
GCN2_Spur        --LNHENVVRYYNSWIEVAEEPPTTDTD------------------ESR--------TT-
GCN2~b_Spur      --LEHANIVHYLAMNYNKG-----------------------------------------
CC1G_02807_Ccin  --LNHRFIVRYYTTWIETTEAPSTTVSD------------------DSS--------AE-
AqueK195_Aque    --MNHENIVRYYNAWIEKYSEPNHHGNE------------------EEG--------EE-
AqueK195~b_Aque  RFINHSSIVKYLLMRHNLT-----------------------------------------
AqueK194_Aque    --MNHENIVRYYNAWIEKYSEPNHHGNE------------------EEG--------EE-
AqueK194~b_Aque  RFISHSSIVKYLLMRHNLT-----------------------------------------
AqueK193_Aque    --FKHSGIVQYYCSFID-------------------------------------------
PEKc_Smoe        --LQHQHVVRYYQAWFETAAGGSS-GTP------------------Y-G--------EE-
PEKa_Smoe        --LQHQHVVRYYQAWFETAAGGSS-GTP------------------Y-G--------EE-
GK065_Glam       --LLHPFIVKYYYSWIETTSDTVQNATE------------------A-P--------NS-
                           *

GCN2_Hsap        ------------------------------------------------------------
GCN2~b_Hsap      ------------------------------------------------------------
Gcn2_Dmel        ------------------------------------------------------------
Gcn2~b_Dmel      ------------------------------------------------------------
GCN2_Mmus        ------------------------------------------------------------
GCN2~b_Mmus      ------------------------------------------------------------
GCN2_Scer        ------------------------------------------------------------
Y81G3A.3_Cele    KIGKKGKLKTGKSLEDKENKANLGGGDSLMPMNLRGLVKDHSIGVDAKEWSTPFGKPEGP
DDB0216407_Ddis  ------------------------------------------------------------
IfkB_Ddis        ------------------------------------------------------------
11434_Tthe       ------------------------------------------------------------
18670_Tthe       ------------------------------------------------------------
21870_Tthe       ------------------------------------------------------------
GCN2_Spur        ------------------------------------------------------------
GCN2~b_Spur      ------------------------------------------------------------
CC1G_02807_Ccin  ------------------------------------------------------------
AqueK195_Aque    ------------------------------------------------------------
AqueK195~b_Aque  ------------------------------------------------------------
AqueK194_Aque    ------------------------------------------------------------
AqueK194~b_Aque  ------------------------------------------------------------
AqueK193_Aque    ------------------------------------------------------------
PEKc_Smoe        ------------------------------------------------------------
PEKa_Smoe        ------------------------------------------------------------
GK065_Glam       ------------------------------------------------------------


GCN2_Hsap        ---------------------PLAKDDR-AARGQPASD-TDG-----------LDSVEAA
GCN2~b_Hsap      ------------------------------------------------------------
Gcn2_Dmel        ------------------------------------------------------------
Gcn2~b_Dmel      ------------------------------------------------------------
GCN2_Mmus        ---------------------PQAQDSP-ATCGKTSGD-TEE-----------LGSVEAA
GCN2~b_Mmus      ------------------------------------------------------------
GCN2_Scer        ------------------------------------------------------------
Y81G3A.3_Cele    KCASRMRQSKRSTPSGGLKHLSECSSDDEDDDDS--------------------------
DDB0216407_Ddis  ---------------------SESESSE------S-EESS--------------ESEE--
IfkB_Ddis        ---------------------SGSISMS-DGNGSG-YEAT--------------DDEDI-
11434_Tthe       ---------------------NNNLYSD-D-NSPSVSEA-YQ--------------KNKS
18670_Tthe       ---------------------DELREDSKEEECS--------------------------
21870_Tthe       ---------------------SQ-MSDQ-DDDNG--------------------------
GCN2_Spur        ---------------------GTGETSP-DTNGVG-RG-A-REVPLAVNSLSLSDNIEEQ
GCN2~b_Spur      ------------------------------------------------------------
CC1G_02807_Ccin  ---------------------SSMITSS-EVTSI--PD-DD-------------------
AqueK195_Aque    ---------------------FS-DSSE-DEDTTE-EE-E--------------EEEEER
AqueK195~b_Aque  ------------------------------------------------------------
AqueK194_Aque    ---------------------FS-DSSE-DEDTTE-EE-E---------------EEEER
AqueK194~b_Aque  ------------------------------------------------------------
AqueK193_Aque    ------------------------------------------------------------
PEKc_Smoe        ---------------------SE-ISSS-WVDTP--------------------------
PEKa_Smoe        ---------------------SE-ISSS-WVDTA--------------------------
GK065_Glam       ----------------------SMISSG-CTTGT--------------------------


GCN2_Hsap        APPPILSSSVE-WSTSGERSASARFPATGPGSSDDEDDDE-DEHG-----------GVF-
GCN2~b_Hsap      ------------------------------------------------------------
Gcn2_Dmel        ------------------------------------------------------------
Gcn2~b_Dmel      ------------------------------------------------------------
GCN2_Mmus        APPPILSSSVE-WSTSAERSTSTRFPVTGQDSSSDEE-DE-DERD-----------GVF-
GCN2~b_Mmus      ------------------------------------------------------------
GCN2_Scer        ------------------------------------------------------------
Y81G3A.3_Cele    -------SEID-WDAESEEVE---------DEESDDSDEE-DEDDGERLVQLNTETSTG-
DDB0216407_Ddis  --------SSES-SES-EESEE--------SEYSDDSEFE-SEENNDFD-------QSF-
IfkB_Ddis        -----IN-NSGSFDDN-ENDDD--------DEEDDDDEYD-E-EDDDYE--------TF-
11434_Tthe       D----YNR--S-YALSKQTNQT--------------------------------------
18670_Tthe       -------S-------------------------ENDSAPSKASKESSMCF--EFIESSEE
21870_Tthe       -----------------E----------------LSDDRY-RYRS-----------NNF-
GCN2_Spur        ALKLSIRNSLE-WSSSGNIG-----------LIGDSDDSS-SDDE-----------GVF-
GCN2~b_Spur      ------------------------------------------------------------
CC1G_02807_Ccin  --------------------SERHLPINGGFDLGDLD-DL-DDEL-----------G---
AqueK195_Aque    EEGLS---FIE-FKLDE--S-----------TTLNSSDQI-RDDS-----------YSF-
AqueK195~b_Aque  ------------------------------------------------------------
AqueK194_Aque    EEGLS---FIE-FKLDE--S-----------TRLDSSDQI-RDDS-----------YSF-
AqueK194~b_Aque  ------------------------------------------------------------
AqueK193_Aque    ------------------------------------------------------------
PEKc_Smoe        ------------------------------------------------------------
PEKa_Smoe        ------------------------------------------------------------
GK065_Glam       ---------------------------------GDDS------LEGSLGA----VTRAL-


GCN2_Hsap        -SQSFLPASDSES----DIIFDNED-----------------------------------
GCN2~b_Hsap      ------------------------------------------------------------
Gcn2_Dmel        ------------------------------------------------------------
Gcn2~b_Dmel      ------------------------------------------------------------
GCN2_Mmus        -SQSFLPASDSDS----DIIFDNED-----------------------------------
GCN2~b_Mmus      ------------------------------------------------------------
GCN2_Scer        ------------------------------------------------------------
Y81G3A.3_Cele    -ADSVFERSTADE----DVVFTAESE----------------DLNAK-------------
DDB0216407_Ddis  -SEVFLFQNGNKR----SLEFDLTDDSYSFLHSDCGFLLEVFDLNNKIGGNNTRSMGSSN
IfkB_Ddis        ---------------------DF-------------------------------------
11434_Tthe       --QSYVLSYNNDN--LSCIEWEQSEN----------------------------------
18670_Tthe       SSLPFEFENYSDN----GIVFEDSDG----------------DEEQK-------------
21870_Tthe       -SSRYQDNNSSY--------YD--------------------------------------
GCN2_Spur        -GRSFLPRSDDSS--SDGIDFEGSDR----------------------------------
GCN2~b_Spur      ------------------------------------------------------------
CC1G_02807_Ccin  -SQSSFPS----------IHFEGSKS----------------------------------
AqueK195_Aque    -SSDVFTDTEDRDVFKGKVDTPGTNV---------------------------ATLLEAD
AqueK195~b_Aque  ------------------------------------------------------------
AqueK194_Aque    -SSDVFTDTEDRDVFKGKVDTPGTNV---------------------------ATLLEAD
AqueK194~b_Aque  ------------------------------------------------------------
AqueK193_Aque    ------------------------------------------------------------
PEKc_Smoe        ------------------------------------------------------------
PEKa_Smoe        ------------------------------------------------------------
GK065_Glam       ------------------------------------------------------------


GCN2_Hsap        -----------------------E--------NSKS--QNQDEDCNEK------------
GCN2~b_Hsap      ------------------------------------------------------------
Gcn2_Dmel        ------------------------------------------------------------
Gcn2~b_Dmel      ------------------------------------------------------------
GCN2_Mmus        -----------------------E--------NSKS--QNQDEDCNQK------------
GCN2~b_Mmus      ------------------------------------------------------------
GCN2_Scer        ------------------------------------------------------------
Y81G3A.3_Cele    -----------RR-------------------ES--------IELMEIN-----------
DDB0216407_Ddis  QHLQQQQQQNQSQQQKKQPQ-QNQSQQQKKLKNSNSKSKSKSKSKSKSK---SK------
IfkB_Ddis        ----------------------------------------QDKSRVV------S------
11434_Tthe       ------------EN--QNPNISNNDGIKKK--LDDS--QTIN-EYREQ------------
18670_Tthe       -----------QKN--QNSSTANNKQETHKRKESQI------QDIDETD-----------
21870_Tthe       -----------------------L--------SSLR--NSQDSSVREQS-----------
GCN2_Spur        ------------G----------E--------ESDI-SLSISNRVKESKGNRG-------
GCN2~b_Spur      ------------------------------------------------------------
CC1G_02807_Ccin  ------------P----------A--------NSDS--SG-DDSLFDSM-----------
AqueK195_Aque    LMVTTPRRGFIHS----------E--------SSDS-VVFQDTSLMAPPGGEGEEGSTAA
AqueK195~b_Aque  ------------------------------------------------------------
AqueK194_Aque    LMVTTPRRGFIHS----------E--------SSDS-VVFQDTSLMAPPGGEGEEGSTAT
AqueK194~b_Aque  ------------------------------------------------------------
AqueK193_Aque    ------------------------------------------------------------
PEKc_Smoe        ------------------------------------------------------------
PEKa_Smoe        ------------------------------------------------------------
GK065_Glam       -----------------DSPS--------------------------ST-----------


GCN2_Hsap        -------N-GCHE--SEPSVTTEAVHYLYIQMEYCEKSTLRDTIDQGL------------
GCN2~b_Hsap      ----------------------DDSIVVDILVEHISGVSLAAHLSHSG------------
Gcn2_Dmel        -----------------------EGLLVYLVQDFLLGTSVFSISSS-L------------
Gcn2~b_Dmel      --------------------------DMYIQMEFCEKCTLRTAIDDNL------------
GCN2_Mmus        -------D-GSHE--IEPSVTAEAVHYLYIQMEYCEKSTLRDTIDQGL------------
GCN2~b_Mmus      ----------------------EDSIVIDILAEHVSGISLATHLSHSG------------
GCN2_Scer        -------------------------SMLFIQMEYCENRTLYDLIHSENL-----------
Y81G3A.3_Cele    ----TTTTSKSKL--AIDVVPVRKPRILCIQMEYCDRATLRQYIDENHC-----------
DDB0216407_Ddis  ----SNSKKSISSSKLKNIKKSTSIPYLYIQMEYCQK-ILRNLTETGM------------
IfkB_Ddis        ----NNSKLSTSS---SRKKPPKETHTLYIQMEYCSKKTLKTLIDNVG------------
11434_Tthe       -------N-KSHK-TFNFTKEPSQLLTLYIQLEYCSGKTLRNYLDEQTH-----------
18670_Tthe       ----FFTKEDKKK--HHKKKKSKDFRLLHIQMEFCGGSTLREMIDNHFFCAE-----KEK
21870_Tthe       -------GKNQEN--QKYPVTNFKLMILFIQLEYCPS-TLSHQIKELKF-----------
GCN2_Spur        ----K--SKEEDI--SEDNPVFSPVQYLYIQMEFCEKSTLRTAIDAGM------------
GCN2~b_Spur      ----------------------KEDINVQLLMEYVGGGNLSQKLENSSL-----------
CC1G_02807_Ccin  ----S--PTNKNL--T-FPSNFGPSRTLYIQMEFVERQTLRERVDEG-I-----------
AqueK195_Aque    AGGGG--GAGGGR---AKQKQTGQSQYLYIQMEYCSNQTLKVLIDSGQ------------
AqueK195~b_Aque  ----------------------EHGILVEVTMEYITGGSLNSLLQGSSSS----------
AqueK194_Aque    G---G--GGAGGR---AKQKQTGQSQYLYIQMEYCSNQTLKVLIDSGQ------------
AqueK194~b_Aque  ----------------------EHGILVEVGMEYITGGSLNSLLQGSSSS----------
AqueK193_Aque    ------------------------------------------------------------
PEKc_Smoe        -----------GS---SSNDVNTVSTFLYIQMEYCPR-TLREVFDTRS------------
PEKa_Smoe        -----------GS---SSNDVNTVSTFLYIQMEYCPR-TLREVFDTRS------------
GK065_Glam       ----PFSTP-KPT--RSTERREIEKVIVFVQMEYCSHGCLSGFIQQCSDGAALCPPLAQG


GCN2_Hsap        YRDT---VRLWRLFREILDGLAYIHEKGMIHRDLKPVNIFLDSDDH-----VKIGDFGLA
GCN2~b_Hsap      PIPV---HQLRRYTAQLLSGLDYLHSNSVVHKVLSASNVLVDAEGT-----VKITDYSIS
Gcn2_Dmel        GWCM---DGARMVARGVLDALVFLHNKGVSHSHLLDTTVFMDNTGN-----VRVSDFSLV
Gcn2~b_Dmel      FNDT---DRLWRLFREIAEGLAHIHQQGIIHRDLKPVNIFLDSHDQ-----IKIGDFGLA
GCN2_Mmus        FRDT---SRLWRLFREILDGLAYIHEKGMIHRDLKPVNIFLDSDDH-----VKIGDFGLA
GCN2~b_Mmus      PVPA---HQLRKYTAQLLAGLDYLHSNSVVHKVLSASSVLVDAEGT-----VKITDYSIS
GCN2_Scer        NQQR---DEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRN-----VKIGDFGLA
Y81G3A.3_Cele    FNAP---TEVWRIFSEVLCGLKYMHDMAMIHRDIKPLNIFLTSQNG-----VKIGDFGLA
DDB0216407_Ddis  NLED---DDIWKLFRQIVEGMAYVHGQGIIHRDLKPSNIFFDSCGD-----IKIGDFGLA
IfkB_Ddis        GIAE---EEAFRLLRQIVEGLNHIHSQQIIHRDLKPANIFIDNEQN-----VKIGDFGLA
11434_Tthe       GLDS---KEAFQIFSQMLEGVNYLHKNQIIHRDLKPSNILFEN-KI-----AKIADFGLS
18670_Tthe       RISS---KQKKSLLAQILEALKYLHEKELIHRDLKPQNILLDQSGQ-----IKLVDFGLA
21870_Tthe       QQDT---VQIWQYFRQILEGLNYIHSQNTIHRDLKPENIFIDCLGD-----IKIGDFGLA
GCN2_Spur        YEDK---RRLWTHFREIIEGLAHIHLQGMIHRDLKPVNIFLDSNDF-----VKIGDFGLA
GCN2~b_Spur      -TSF---DLLREYAIDLLSGLQYLHSHAVVHKQLRASQVYVDCDGR-----LRVANYSMC
CC1G_02807_Ccin  --SE---EEGWRLFHQIVDALVHMANLGIIHRDIKLTNIFIALAKIMGLTLFPVGDFGLA
AqueK195_Aque    LVKSPGFELGWQLFREITEGLAHIHSQGMIHRDLKPVNIFLNSSGH-----CKIGDFGLA
AqueK195~b_Aque  PITG---KSLQLYSKQLLEAVAYLHSQGIVHNDIRPSLVFIDPVQG-----VKLAGHTII
AqueK194_Aque    LIKSSGFELGWQLFREITEGLAHIHSQGMIHRDLKPVNIFLNSSGH-----CKIGDFGLA
AqueK194~b_Aque  PITG---KSLQLYSKQLLEAVAYLHSQGIVHNDIRPSLVFIDPVQG-----VKLAGHTII
AqueK193_Aque    ------------------------------------------------------------
PEKc_Smoe        VLDK---ELTWGIFRQIVEGLSHIHGQGIIHRDLTPSNIFFDTRND-----VKIGDFGLG
PEKa_Smoe        VLDK---ELTWGIFRQIVEGLSHIHGQGIIHRDLTPSNIFFDTRND-----VKIGDFGLG
GK065_Glam       LTLT---ELLWRMTAQLASAVAYIHSKDIVHYDIKPANVFLDESYN-----IKLGDFGTS


GCN2_Hsap        TDHLAFSADS---KQ---DD---QT---G-------------------------------
GCN2~b_Hsap      KRLADICKED---VF---E----QT-----------------------------------
Gcn2_Dmel        PNLLELLSGA--------------------------------------------------
Gcn2~b_Dmel      TTSFLALQAH---DA---AP---A------------------------------------
GCN2_Mmus        TDHLAFTAEG---KQ---DD---QA---G-------------------------------
GCN2~b_Mmus      KRLADICKED---VF---E----QA-----------------------------------
GCN2_Scer        KNVHRSLDIL---KL---DS---QN-----------------------------------
Y81G3A.3_Cele    TLEAMSSKGKIV-GG-AAEKS--TS-IEA-----------------------------M-
DDB0216407_Ddis  INNKTTSTLSPTTNI---NS---STSSAG---SLTTSSNSVQSVINTKQQQQQQQPQNYW
IfkB_Ddis        TSGAPVSKSD---DL---NS---STSNAA---NN----------------------INLS
11434_Tthe       IQQELGLINA---NQ------E-LP-S---------------------------------
18670_Tthe       TTLKKERQIERK-AVLNLKRA--SS-VQSNFYNA------------------S----SLP
21870_Tthe       KSQKQNVFSK---YQYVIEKEE-NE-LFNQLVN---------------------------
GCN2_Spur        TSEQMAGALT---SE---VS-CHNR-L-T-------------------------------
GCN2~b_Spur      KRLNELAQAA---NE---G----KQ-----------------------------------
CC1G_02807_Ccin  TSSLAAVDPS---DV--------QH-----------------------------------
AqueK195_Aque    TTFSKYHTGL---SR---Q----QS-I---------------------------------
AqueK195~b_Aque  KRLSDLTGK----VN---E----EA-----------------------------------
AqueK194_Aque    TTFSKYHTGL---SR---Q----QS-I---------------------------------
AqueK194~b_Aque  KRLSDLTGK----VN---E----EA-----------------------------------
AqueK193_Aque    ------------------------------------------------------------
PEKc_Smoe        VCAAKFADLQ---NP---DQ-D-HR-V---------------------------------
PEKa_Smoe        VCAAKFADLQ---NP---DQ-D-HR-V---------------------------------
GK065_Glam       YTCKGPSDDQD-----------------------------------------------L-


GCN2_Hsap        -----------------D---LIKSDPSGHLTGMVGTALYVSPEVQGS------------
GCN2~b_Hsap      ------------------RVRFSD------------------------------------
Gcn2_Dmel        ------------------------------------------------------------
Gcn2~b_Dmel      ------------------PVNQITSAEDGTGTGKVGTTLYVAPELTGN------------
GCN2_Mmus        -----------------D--GVIKSDPSGHLTGMVGTALYVSPEVQGS------------
GCN2~b_Mmus      ------------------RVRFSD------------------------------------
GCN2_Scer        ---------------------LPGS--SDNLTSAIGTAMYVATEVLDG------------
Y81G3A.3_Cele    ----------------LSPNGVKSKGSDVHQTRDIGTQLYMAPELFVDE-----------
DDB0216407_Ddis  EDEVEGQQQQQQQQQQQQQQQQQQQQQQQQHTARVGTLFYTSPEQEAGT-----------
IfkB_Ddis        ---------SSTNSTAQQTPMWDLNDENLSMTGGVGTPFYCCPEILEKN-----------
11434_Tthe       ------------------QKNIDGQDISVAHTGNVGTPFYMPPEQQDK------------
18670_Tthe       ---------GEIDYK-DKKSENSNNYFPSEITRGVGTGVYRAPEQEN-------------
21870_Tthe       -----------------KQYLTEKELEAIDQTLNVGTYFYRPPAS---------------
GCN2_Spur        -----------------DSSHSGEATPGNHLTGKVGTALYVAPELCKA------------
GCN2~b_Spur      ------------------TVRFSDD-----------------------------------
CC1G_02807_Ccin  -----------------KP---VTY--DPEMTLEVGTRLYIAPEVQWTG-----------
AqueK195_Aque    ------------------PSN--TS-ILAGDTGLVGTMLYLAPELLKS------------
AqueK195~b_Aque  ------------------WPR---------------------------------------
AqueK194_Aque    ------------------PSN--TS-ILAGDTGLVGTMLYLAPELLKS------------
AqueK194~b_Aque  ------------------WPR---------------------------------------
AqueK193_Aque    ------------------------------------------------------------
PEKc_Smoe        ------------------PVKFEANVKSLEGTGQVGTYFYRAPEIEQA------------
PEKa_Smoe        ------------------PVKFEANVKSLEGTGQVGTYFYRAPEIEQA------------
GK065_Glam       ------------------------------FASDRSTLSYMAPELSAQHWMQSSLNNAAQ


GCN2_Hsap        ---TKSAYNQKVDLFSLGI--------------------IFFEMSYHPMVTASERIFVLN
GCN2~b_Hsap      -NALPYKTGKKGDVWRLGL--------------------LLLSLSQG-QECG--------
Gcn2_Dmel        -----GQSSSCGDLPALGA--------------------LVESLM-PT------------
Gcn2~b_Dmel      --ASKSVYNQKVDMYTLGI--------------------ILFEMCQPPFDTSMERAQTIM
GCN2_Mmus        ---TKSAYNQKVDLFSLGI--------------------IFFEMSYHPMVTASERIFVLN
GCN2~b_Mmus      -SALPYKTGKKGDVWRLGL--------------------LLLSLSQG-QECG--------
GCN2_Scer        ----TGHYNEKIDMYSLGI--------------------IFFEMIY-PFSTGMERVNILK
Y81G3A.3_Cele    -LVHKAPYTSKIDIYSAGV--------------------VLFEMFYRPLPPSMDRVSTLN
DDB0216407_Ddis  --NGDSAYDDKVDMYSLGI--------------------VFFEMWYV-FSTGHERVIVLR
IfkB_Ddis        ----TKHYGTKVDMYSLGI--------------------IFFEMCFQ-FQTQMERSNILR
11434_Tthe       ----SGKYNEKIDVYSLGI--------------------ILLEIIHK-MDTYHEKLEIVK
18670_Tthe       ----TSSYCTKADMFSLGILNQAKQYFNNLIFKINKIGVIIFEMWYP-LPTFMEKYQTLK
21870_Tthe       ----QSMHEERADIYALGI--------------------IFFEMWFY-FQSKYQRFKVLT
GCN2_Spur        ---RIGHYNQKVDLYSLGI--------------------IFFEMCYRSLSTGMERVKILG
GCN2~b_Spur      -KTYGGRGGKKGDVLDLGL--------------------LLLGLLLG-TSDV--------
CC1G_02807_Ccin  -RRAAPKNHNKADMYSLGI--------------------VFFEMNYR-FTTGSERIVVLE
AqueK195_Aque    ----VVKYTQKVDMYSLGI--------------------ILYEMSHPPPATVMERVKILT
AqueK195~b_Aque  -GFFTKLGGKKTDILKLGM--------------------VIFCMSVG-RVTV--------
AqueK194_Aque    ----VVKYTQKVDMYSLGI--------------------ILYEMSHPPPATVMERVKILT
AqueK194~b_Aque  -GFFTKLGGKKTDILKLGM--------------------VIFCMSVG-RVTV--------
AqueK193_Aque    ------------------------------------------------------------
PEKc_Smoe        ----WPHIDEKVDMYSLGV--------------------ILFELWHP-FSTGMERYVTLN
PEKa_Smoe        ----WPHIDEKVDMYSLGV--------------------ILFELWHP-FSTGMERYVTLN
GK065_Glam       SNLPVTALRKQADMYSLGI--------------------TLLELWFL--PTASDNLSNLR


GCN2_Hsap        QLRDPTSPKFPEDFDD-GEH----AKQKSVISWLLNHDPAKRPTATELLKS------ELL
GCN2~b_Hsap      --------EYPVTIPS-DLP----ADFQDFLKKCVCLDDKERWSPQQLLKH------SFI
Gcn2_Dmel        ----------------------NSYEMRDFVD---KCNSDRTLSASELLEH------PFL
Gcn2~b_Dmel      ALRNV-SINIPDAMLKDPKY----EKTVKMLQWLLNHDPAQRPTAEELLIS-------DL
GCN2_Mmus        QLRDPTSPKFPDDFDD-GEH----TKQKSVISWLLNHDPAKRPTAMELLKS------ELL
GCN2~b_Mmus      --------EYPVTIPS-DLP----ADFQDFLKKCVCLDDKERWSPQQLLKH------SFI
GCN2_Scer        KLRSV-SIEFPPDFDD-NKM----KVEKKIIRLLIDHDPNKRPGARTLLNS------GWL
Y81G3A.3_Cele    NLRDD--IKIPSDFGA-GLAAPMAGLARRTVEKMLQRNPDERPTADDLLN------DEDL
DDB0216407_Ddis  NLREK--FEFPSDFER-NH-----SRQATLIRMLIDKDPAKRPSAQQLLQS------ELM
IfkB_Ddis        DLRDN--LKFPPGFES-TK-----PDQTQIIRSLLSRDPTQRPSTKQLLES------GLL
11434_Tthe       KLKGS--QELPKNLQK-TQ-----KYACELIIQMTSLKPQNRPSIEQILQG-----KTYM
18670_Tthe       EIREK--NQLPQDFNL-KVGN-DAKEIRDILTKLLDPDPSKRYSAEELLK--------TL
21870_Tthe       ILRNN--NLFPDQFEQ-FH-----PKQAKLIAWMLNFSSQKCQKVMEIMQS------DLI
GCN2_Spur        QIRQE-SIQLPEDFDE-VRN----TNENAIVHWLLNHDPKERPTSQELLES------KLL
GCN2~b_Spur      --------QYPCEVPQ-DLP----LDLQDFLNRCIDIDERSRANVQSLLDH------PFI
CC1G_02807_Ccin  DLRKP-GIFFPTSWEP-HR-----TRQREIITWLLQHDPEKRPSALDLSQS------PLM
AqueK195_Aque    DVRKK-EIVFSERFKT-SKK----MSKQAVEHTLQNPNSSQYKRLMEKL--------FSQ
AqueK195~b_Aque  --------SYPPDVPE-HFS----EDFKDFLNKCLNNNEYQRYPAHELLVH------PFI
AqueK194_Aque    DVRKK-EIVFSERFKT-SKK----MSKQAVEHTLQNPNSSQYKRLMEKL--------FSQ
AqueK194~b_Aque  --------SYPPDVPE-HFS----EDFKDFLNKCLNNNEYQRYPAHELLVH------PFI
AqueK193_Aque    -----------------------------------------------------------D
PEKc_Smoe        ELKQQ--NILPSNWAA-KF-----PHQAALVHLLVSPHPQDRPSAREVLQS------ELL
PEKa_Smoe        ELKQQ--NILPSNWAA-KF-----PHQAALVHLLVSPHPQDRPSARDVLQS------ELL
GK065_Glam       VLVQN--KQLPSEFTE-THP-----NVSAILYQLCDVHPLKRLTASALIEALSALNLPVI