Protein (view, download) , Domain (view, download)
ak1_Ddis         MQPVPSD----PN-----------------------------------------------
10338_Tthe       MGQNICVSTK--------------------------------------------------
AlphaK2_Hsap     MKDSEG------------------------------------------------------
AlphaK3_Hsap     MEVAWLV----YVLGQQPLARQGEGQSRLVPGRGLVLWLPGLPRSSPSWPAVDLAPLAPA
AlphaK1_Hsap     MNNQKVVAVLLQ------------------------------------------------
AlphaK1_Mmus     MNNQDAVASILH------------------------------------------------
AlphaK2_Mmus     MTDPGC------------------------------------------------------
AlphaK3_Mmus     MGSRRAA----G------------------------------------------------
CC1G_14582_Ccin  MSSRQG------------------------------------------------------
CC1G_06337_Ccin  MSSRQG------------------------------------------------------
CC1G_14302_Ccin  MSQTTC-----P------------------------------------------------
CC1G_08873_Ccin  MARCSG------------------------------------------------------
CC1G_12594_Ccin  MARCSG------------------------------------------------------
CC1G_11146_Ccin  MEPIKQR----S------------------------------------------------
CC1G_00657_Ccin  MTPTVEC----P------------------------------------------------
CC1G_02529_Ccin  MT----------------------------------------------------------
CC1G_10953_Ccin  MT----------------------------------------------------------
CC1G_07428_Ccin  MARCSG------------------------------------------------------
                 *

ak1_Ddis         ---------------------YGLLRS-LFQD-PN-NQ--------CCA-----------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     ----------------------P-QRP-PL-C-FL-ST--------LL------------
AlphaK3_Hsap     RPRGPLICHTGHEQAGREPGPGSSTKGPV--L-HDQDT--------RCAFLPRPPGPLQT
AlphaK1_Hsap     ---------------------ECKQVL-DQ-LLLE-APDVSEEDKSEDQ-----------
AlphaK1_Mmus     ---------------------ECKQVL-DR-LLLE-TPDVSTEDKSEDQ-----------
AlphaK2_Mmus     -----------------------PERR-TL-C-FL-ST--------LL------------
AlphaK3_Mmus     ------------------------------------------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ---------------------TCHHRF-F--R-LE-NP--------PC------------
CC1G_08873_Ccin  ----------------------CSQRF-DL-L-VE-GT--------RCG-----------
CC1G_12594_Ccin  ----------------------CSQRF-DL-L-VE-GT--------RCG-----------
CC1G_11146_Ccin  ---------------------MV--------L-L-RSM--------FNA-----------
CC1G_00657_Ccin  ---------------------LCDQAF-Q--M-PS-GA--------VCG-----------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ----------------------CSLRF-EF-L-AE-GM--------RC------------


ak1_Ddis         ---------------------------------ECNSA----------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     ------------------------------------------------------------
AlphaK3_Hsap     RRYCRHQGRQGSGLGAGPGAGTWAPAPPGVSKPRCPGRA----RPGEGQQQVTTARPPAI
AlphaK1_Hsap     ---------------------------------RCRALLPSELRTLIQ-------EAKEM
AlphaK1_Mmus     ---------------------------------RCRASLPSELRTLIQ-------EAEEM
AlphaK2_Mmus     ------------------------------------------------------------
AlphaK3_Mmus     ------------------------------------------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ---------------------------------RCTKRAPRP---------------NVE
CC1G_12594_Ccin  ---------------------------------RCTKRAPRP---------------NVE
CC1G_11146_Ccin  ---------------------------------KHT------------------------
CC1G_00657_Ccin  ---------------------------------RCRKLQGHD-RNSDT-------YRQIM
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ------------------------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     ------------------------------------------------------------
AlphaK3_Hsap     NRGARQPRAGAAAAGRGPGAGAWRTGEAAASAGP--------------------------
AlphaK1_Hsap     ------------------------------KWPFVPEKWQYKQAVGPEDKTNLKDVIGAG
AlphaK1_Mmus     ------------------------------KWPFVPEKWQYKQAMSPEDKTNLQDVIGAG
AlphaK2_Mmus     ------------------------------------------------------------
AlphaK3_Mmus     ------------------------------------------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------EWGM--------------------------
CC1G_12594_Ccin  ------------------------------EWGM--------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------SWPQ--------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ------------------------------------------------------------
10338_Tthe       -------------------TGDVYKFH---------------------------------
AlphaK2_Hsap     ------------------------------------------------------------
AlphaK3_Hsap     ----------------AVGEGGAMGSRRAPSRGWGAGGRSGAGGDGEDDGPVWIPSPA-S
AlphaK1_Hsap     LQQLLASLRASILARDCAAAAAIVFLVDRFLYGLDVSGKLLQVAKG--LHKL-----QPA
AlphaK1_Mmus     LQQLLAALRASILVQDCAAASAIVFLMDRFLYGLDVSGKLLQVAKG--LHKL-----KPA
AlphaK2_Mmus     ------------------------------------------------------------
AlphaK3_Mmus     -------------------------------RGWGLGGRAGAGGDSEDDGPVWTPGPA-S
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ----------------CNKCGEVFEFMDQ-------------------------------
CC1G_12594_Ccin  ----------------CNKCGEVFEFMDQ-------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ----------------CVACGACFQNMSLPVNGVQLCGKPGCRDGGEQTGQSQSLTPMGS
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ------------------------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     ---------------------------------------------------SQKVPEKSD
AlphaK3_Hsap     RSYLLSVRPET---SLSSNRLSHPSSGRSTFCSIIAQLTEETQPLFETTLKSRSVSEDSD
AlphaK1_Hsap     TPIAPQVVIRQARISVNSGKLLKA------------------------------------
AlphaK1_Mmus     TPIAPQVVIRQARVSVNSGKLLKA------------------------------------
AlphaK2_Mmus     ---------------------------------------------------SQKVPEKSD
AlphaK3_Mmus     RSYLLSVRPEA---SLSSNRLSHPSSGRSTFCSIIAQLTEETQPLFETTLKSRAVSEDSD
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  NPIPPSIHINN---SLSNNSLLRSE-----------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ------------------------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     AVLRCIISGQPK------PEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDA
AlphaK3_Hsap     VRFTCIVTGYPE------PEVTWYKDDTELDRYCGLPKYEITHQGNRHTLQLYRCREEDA
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     VVLRCMIAGQPK------PEVTWYKNGQAIDLGGTVSSYEFFENQYIHLLHLSCCTQSDA
AlphaK3_Mmus     VRFTCIVTGYPE------PEVTWYKDDIELDRYCGLPKYEITHQGNRHTLQLYRCQEEDA
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  --PKCR-ARTPGLSSLLVSQL---------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------ITGSPR------V-----------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  --GRCT-NRPAR------DSI---------------------------------------


ak1_Ddis         NVPYVCIK--LGVFICPTCAHFLSTLG-FKVRPIMGSSFSEEDISRLQSIGNLVSKQFWL
10338_Tthe       --------------------------------HSC-------------------------
AlphaK2_Hsap     AVYQISAKNSFGMICCSASVEVECSSENPQLSPNL-----EDDRDRG-------------
AlphaK3_Hsap     AIYQASAQNSKGIVSCSGVLEVGTMTE-YKIHQRW-------------------------
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     AVYQVSARNCVGMICCSASLEVQCLQD-PQVSPDP-----GGGRDAA-------------
AlphaK3_Mmus     AIYQASARNTKGIVSCSGVLEVGTMTE-YKIHQRW-------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ARWTPMDIVMPPPEDPNLESFLRLKYIEKRWTSSL---STSD----G-F-----SSPNN-
10338_Tthe       ---FAEGS---------SRKA---------------------------------------
AlphaK2_Hsap     --WKHETG---------THEEERANQIDEKEHPYKEEESISPGTPRSADS-----SPSKS
AlphaK3_Hsap     ---FAKLK---------RKAAAKLREIEQSWKHEKA---VPG----EVDT-LRKLSPDRF
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     --GECKTE---------IREEDSINHTDEKWNPCKKGES-------TADS-----FLDKF
AlphaK3_Mmus     ---FAKLK---------RKAAAKMREIEQSWKHGKE---ASG----EADTLLRKISPDRF
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  -----------------------------------------------------------F
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ----------------NNTSNVNNINNNSNHNNNINNNNNNINN-----NNNNNINNNNN
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     NHSLSLQSLGNLDISVSSSENPLGVKGTRHTGEAYDPSNTEEIANGLLFLNSSHIYEKQD
AlphaK3_Hsap     QRKRRLSGAQAPGPSVPTREPEGGTLAA--------------------------------
AlphaK1_Hsap     ----------------------------EYILSSLISNNGATGT-----WLYRNESDKVL
AlphaK1_Mmus     ----------------------------EYILSSLISNNGATGT-----WLYRNESDKVL
AlphaK2_Mmus     NHLSSPQIVARGDSGASNSENPQYIKETRQRMGQYNSNNMQENS-----FNSNNTAEKQD
AlphaK3_Mmus     QRKRRLSGVEEAVLSTPVREMEEGSSAA--------------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  QTETY-------------LNQEGGITIE--------------------------------
CC1G_00657_Ccin  ---------------------------E--------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         IINNFSNINNISNGMNNISLN--NINNNNNNNNHYNGNDIGIPIVHKTQSQPQPQPQPQP
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     R-CCHKTVHSMASKFTDGDLN--NDGPHDEGLR------SSQ-----------------Q
AlphaK3_Hsap     ---------------------------WQEGET------ETA-----------------Q
AlphaK1_Hsap     ----VQSVCIQIRGQILQKLGMWYE-AAELIWASI-----VG-----YLALPQPD-----
AlphaK1_Mmus     ----VQSVCIQIRGQILQKLGMWYE-AAELIWASV-----IG-----YLTLPQPD-----
AlphaK2_Mmus     V-SQLWTVNATVPGLVSDGLG--YE-ESNESVS------PSH-----------------Q
AlphaK3_Mmus     ---------------------------WQEGET------ESA-----------------Q
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ---------------------------GGQMGLTLKQYVDRL-----------------R
CC1G_00657_Ccin  ---------------------------FRNRIR------ARS-----------------R
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         QPQSQGFSPFNSPRSSPKPGRHHLIDDLISFNPTPVN-NSNNNNNN---NNNNNNGNNGN
10338_Tthe       ---------------------------------------------------YR---CEV-
AlphaK2_Hsap     NPKVQKYISFSLPLSEATAHIYPGDSAVANKQPSPQL-SSEDSDSDYELCPEITLT---Y
AlphaK3_Hsap     HSGLGLINSFA-----------SGE-VTTNGEAAPEN-GEDG---EHGLLTYI---CDAM
AlphaK1_Hsap     ---KKGLST------------------SLGILADIFVSMSKNDYEKFKNNPQINLS---L
AlphaK1_Mmus     ---KKGIST------------------SLGILADIFVSMSKTDYEKFKKSPKVNLA---L
AlphaK2_Mmus     TPKVQKYISFSLPLPETTLGPYPEDSNSINMQPGPQV-SSEDSDSDYELCPEITLT---Y
AlphaK3_Mmus     HPGLGLINSFA-----------PGE-APTNGEPAPEN-GEDE---ERGLLTYI---CEVM
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  --------------------------------------------NEKPQCSGCGVYGDLP
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  DDGWITVPTMS-------------------------------------------------
CC1G_00657_Ccin  PEVIVATTRLS-----------S-------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  --------------------------------------------DDWGLCRRCGSV---Y


ak1_Ddis         PLK---------------------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     TEEFSDDDLE-------------------------YLECS-DVM----------------
AlphaK3_Hsap     E--LGPQRALKEESGAKKKKKDEESKQGLRKPELEKAAQSRRSS----------------
AlphaK1_Hsap     LKEFDHHLLS-------------------------AAEAC-KLAAAFSAYTPLFVLTAVN
AlphaK1_Mmus     LKEFDHHLLS-------------------------ASEAC-KLAAAFSAYTPLFVLTAVN
AlphaK2_Mmus     TEEFSDDDLE-------------------------YLECS-DVM----------------
AlphaK3_Mmus     E--LGPQNSPPKESGAKKKRKDEESKPGEQKLELEKAEGSQCSS----------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  TL----------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  EH----------------------------------------------------------


ak1_Ddis         --------------FS--------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     ------------TDYSNAVWQRNLLGTEHVFLLESDDEEMEFGEHCLGGCEHFLSGM---
AlphaK3_Hsap     ------------E-----------------NCIPSSDEPDSCGTQGPVGVEQVQTQPRGR
AlphaK1_Hsap     IRGTCLLSYSSSN-----------------DCPPELKNLHLC------------------
AlphaK1_Mmus     IRGTCLLSYSCSA-----------------DCPPGMKSVHLC------------------
AlphaK2_Mmus     ------------TDYSNAVWQRSLQGTDRVFLLESDDEEMEFNECGLGGCEHFFTEM---
AlphaK3_Mmus     ------------E-----------------NVVPSTDKPNSSRREKSTDTQPAQTQPRGR
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ---------------------------------------SN-GPLCN-LCVAFY------
CC1G_08873_Ccin  -------------------------------------------NVCF-DCSKYT------
CC1G_12594_Ccin  -------------------------------------------NVCF-DCSKYT------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ---------------------------------------LE-GEICF-DCEKYT------


ak1_Ddis         --------------------------------------------GGIPQNNNNNNNNNTT
10338_Tthe       --------------VKGPNLG---------------------------------------
AlphaK2_Hsap     ---GCG---------SR-------------------------------------------
AlphaK3_Hsap     AARGPGSSGTDSTRKPASAVGTPDKAQKAPGPGP-------------------------G
AlphaK1_Hsap     ------------EAKEAFEIGLLTKRDDEPVTG--------------------------K
AlphaK1_Mmus     ------------EAKEAFEIGLLTKKDGELVSG--------------------------K
AlphaK2_Mmus     ---GCG---------PQ-------------------------------------------
AlphaK3_Mmus     VARGPGI---ESTRKTASVLGIQDKVQDVPAPAPAPVPAPALAPAPVPVPAPTPVPSRSS
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ---------------SAKPVGF--------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         TTTTTTNNNN--------------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     ---------------------VSGDAGPMVATAGFCGHHSQPQEVGVRSSRVSKHGPSSP
AlphaK3_Hsap     QEVYF--SLKDMYLENTQAVRPLG--------------EEGPQTLSVRAPGESPKGKAPL
AlphaK1_Hsap     QELHS--FVKAAFGLTTVHRRL---------------------------HGETGTV----
AlphaK1_Mmus     QELHS--FIKAAFGLTTVHSRL---------------------------HGETDAV----
AlphaK2_Mmus     ---------------------VSGGMWSMNVATGFCSYHSQPQEVRVRSSGTSGHSPLPL
AlphaK3_Mmus     EQVYF--SLKDMFMETTRAGRSQE--------------EEKPPPPSTRVAGESPPGKTPV
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  -----------------------KAG-------------------GSA--P---------
CC1G_08873_Ccin  -----------------------AGN-------------------GVQQAS---------
CC1G_12594_Ccin  -----------------------AGN-------------------GVQQAS---------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ----------------------------------------------AALHERENALRQEI
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  -----------------------GDD-------------------GAQQLA---------


ak1_Ddis         ----------------------------KVPFDPFSPIKTF-------------------
10338_Tthe       ------------------KKGVVKR-----------------------------------
AlphaK2_Hsap     QTGMTLILGPHQDGTSSVT----------------------------------------E
AlphaK3_Hsap     RARSEGVPGAPGQPTHSLTPQPTRPFNRKRFAPPKPKGEATTDSKPISSLSQAPECGAQS
AlphaK1_Hsap     -------------------HAAS-----QLCKEAMGKLYNFST----SSRSQDREALSQE
AlphaK1_Mmus     -------------------RAAR-----QLCSEAVGKLYTFST----SPTSQDREGLSQE
AlphaK2_Mmus     HSEMTLTLGPHQDETAKMT----------------------------------------E
AlphaK3_Mmus     KSRLEKVPMVSSQPTSSMVPPPIKPLNRKRFAPPKSKVESTTT----SLSSQTSESMAQS
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  A-----------------DAASVSRAQITI-------VY---------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ------------------------------------------------------------
10338_Tthe       --------YKNHIENKKLDNFKNE------------------------------------
AlphaK2_Hsap     QGRYKL--------------------------------PTAPEAAENDYPGIQGETR--D
AlphaK3_Hsap     LGKA-P--------------------------------PQASVQVPTPPARRRHGTR--D
AlphaK1_Hsap     VMSV-IAQVKEHLQVQSFSNVDDRSYVPESFECRLDKLI-------------LHGQGDFQ
AlphaK1_Mmus     IMSL-ISQVKGHLRVQSFPNLDACSYVPESFKCGLDRLI-------------LHGHVDFQ
AlphaK2_Mmus     PGRAPL--------------------------------PTAPEAVENDCSGIRGETR--D
AlphaK3_Mmus     LGKA-L--------------------------------PSASTQVPTPPARRRHGTR--D
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ------------------------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     SHQAREEFA-SDNLLNMDESVRETEMKLLSGESENSGMSQCWETAADKRVGGKDLWSKRG
AlphaK3_Hsap     STLQGQAGH-RTPG----------------------------------------------
AlphaK1_Hsap     KILDTYSQHHTSVC----------------------------------------------
AlphaK1_Mmus     QILETYSQHHTSVC----------------------------------------------
AlphaK2_Mmus     NPEAGEEFS-GDNLQTMDKVETEASVKPLSGGSDKTEVKQGLESLARERTDEKYPGSKKA
AlphaK3_Mmus     SPLQGQTSH-KTPG----------------------------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  -------GK-KRTG----------------------------------------------
CC1G_00657_Ccin  ---AFRQST-NWKQ----------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ---------------------------SESGEYQNTNGNQQLSGSGN-------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     SRKSARVRQPGMKGNPKKPNANLRES------------------------TTEGTLHLCS
AlphaK3_Hsap     ------------------------------------------------------------
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     ALRPTRARRPGMKANTKK--QLLRDS------------------------APKGTLDLL-
AlphaK3_Mmus     ------------------------------------------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ---------LELLQDPRASQQLLAASADGSA-ATNP-QSQQLLERAL-------------
CC1G_08873_Ccin  ---------REAIANPVNVRTHTNSGGGTSAQFQG-AGNQQLQEEAL-------------
CC1G_12594_Ccin  ---------REAIANPVNVRTHTNSGGGTSAQFQG-AGNQQLQEEAL-------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ---------KNAIANPVDPRKHTLPGGRSSSAESDV-Q--AIDPEAYAKAK---------


ak1_Ddis         ------SLIDILSHP-TQSKSP------------SPSGTPHSLSPQHHSS--DFKVHLID
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     AKESAEPPL-TQSDKRETSHTTAAATG----RSS------------------HADA-REC
AlphaK3_Hsap     ------------------------------------------------------------
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     PKEPTRQPL-PGSYGQEPTHTEAGAPG----WDS------------------HFHA-EVC
AlphaK3_Mmus     ------------------------------------------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------SYQQSASGT-RLGQK--------------PRV-----------T--------GT
CC1G_08873_Ccin  ------RIMSSMSHS-YTDAHARTS-GTRFQGRIAPSK-----------LKLKTAA-ELG
CC1G_12594_Ccin  ------RIMSSMSHS--------------FQGRIAPSK-----------LKLKTAA-ELG
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ----AEVALSRMRNG-YADAMARAAPG----VKVARSK-----------L--KGSL----


ak1_Ddis         -IPTTQQQ-----------------L-------------------QQQQLQLQQQLQQQL
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     AISTQAEQEAKT-LQTSTDSVSKEGNTNCKGEGMQVNTLFETSQVPDWSDPPQVQVQETV
AlphaK3_Hsap     --EV-------LECQTT--------------------------TA---------------
AlphaK1_Hsap     --EV-------FESDCG--------------------------NN---------------
AlphaK1_Mmus     --EV-------FESTCG--------------------------NS---------------
AlphaK2_Mmus     -IPLPAEQDSKI-LRPPADPLSKEEDSSFEGGGALLNKLFEASQIPDRTDHLQMQIQETI
AlphaK3_Mmus     --EA-------LESPAT--------------------------VA---------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  -GPNPV------------------------------------------------------
CC1G_08873_Ccin  -I----------------------------------------------------------
CC1G_12594_Ccin  -I----------------------------------------------------------
CC1G_11146_Ccin  --P---------------------------------------------------------
CC1G_00657_Ccin  --ED-------GTLGSG--------------------------EI---------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         QQQQQQQQQQQQQQQSPISNPFT------------------------SNNNSNSEPLVSI
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     RETISCSQMPAFSEPAGEESPFT------------------------GTTTISFSNLGGV
AlphaK3_Hsap     --------------------PTMSASSSSDVA--SIGVSTSGSQGIIEP-----------
AlphaK1_Hsap     --------------------KNEQKDAKTGVCITAL------------------------
AlphaK1_Mmus     --------------------KRNQRDTKSEVCITTL------------------------
AlphaK2_Mmus     GESSSLDQMLAFSVPAEESSTFA------------------------GATTHSVSNLSEI
AlphaK3_Mmus     --------------------PTKSANSSSDTV--SVDHDSSGNQGATEP-----------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ----------------------------------------------------LFSNLAKA
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  --------------------PFD------------------------AH-----------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         LDKHEDLHNHHHHQQQQHHKQQQQQQQQQQNGNNSP----LAQ-FNQIQQQQINNN----
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     HKENASLAQHSEVKP-------------------------CTCGPQHEEKQ---------
AlphaK3_Hsap     ----------------------------------------MDMETQEDGRTSANQRTGSK
AlphaK1_Hsap     ---------------------------KTEIKNIDTVSTTQEKPHCQRDTGISSSLMG--
AlphaK1_Mmus     ---------------------------KTETNTADTMVATLERVSSQDSRSTASSKMS--
AlphaK2_Mmus     NRENLSLAQYPGLES-------------------------CPQSLQQEGRP---------
AlphaK3_Mmus     ----------------------------------------MDTETQEDGRTLVDGRTGSR
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  HQYNAAKKASLE---------------------------------REKNKK---------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ----------------------------------------K-----TLSVKR--------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ------------------------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     ------------------------------------------------------------
AlphaK3_Hsap     KNVQADGKIQVDGRTRGDGTQ----TAQRTRADRKTQVDAGTQESKRPQSDRSAQKGMMT
AlphaK1_Hsap     --KNVQRELRRGG-----------------------------------------------
AlphaK1_Mmus     --KKDQGKLQRER-----------------------------------------------
AlphaK2_Mmus     ------------------------------------------------------------
AlphaK3_Mmus     KKTHTDGKLQVDGRTQGDGAQDRAHASPRTQAGEKAPTDVVTQGSERPQSDRSSWKNLVT
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         --------------------------NPFVEEKQPHQHPHHLQHHRH------HST---S
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     -------------------DRDGNIPDNFRE-------------DLKYEQSISE------
AlphaK3_Hsap     QGRAETQLETTQAGEKIQEDRKAQADKGTQE-------------DR--------RM----
AlphaK1_Hsap     -------------RRNWTHS-------------------------DAF------RVSLDQ
AlphaK1_Mmus     -------------GRSWTHS-------------------------KAF------RVSLDL
AlphaK2_Mmus     -------------------NRDRDLPGALWA-------------ESACELSLLE------
AlphaK3_Mmus     QRRVDMQVGQMQAGERWQQD-------------------------PGD-----ARI----
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ----------------------------VAI-------------RISSTLYLS-------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------VNDEWGK-------------EG-N-----FKA---I
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         SINHGSNGDL------ASISLTL------------------------LTPSPSPSPSFNY
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     ---------------ANDETM-SPGVFSRHLPKDARADFREPVAVSVASPEP--------
AlphaK3_Hsap     Q--------GEKGMQGEKGTQSE-G-----------SAPTAMEGQSEQEVAT--------
AlphaK1_Hsap     DVETET------------------------------------------------EP-SDY
AlphaK1_Mmus     DMETET------------------------------------------------EP-PNH
AlphaK2_Mmus     ---------------DNEEEE-SQPPASVALPQGDGVPCREPEGLSDSFPQP--------
AlphaK3_Mmus     Q--------E-----EEKETQSAAG-----------SIPVAFETQSEQLSMA--------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  --------------------------------NHKGLRPVPGTREGHTFIQ---------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  Y--------M-------EETDLRR------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         SGGVSSAPN----N----------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     -------TDTALTLENVCDEPRDREAVCAMECFEAGDQGTCFDTIDSLVGRPVDKYSPQE
AlphaK3_Hsap     -------SLGPPSRTPKLPPTAGPRAPLNIECFVQTPEGSCFPKKPGCLPRS--------
AlphaK1_Hsap     SNGEGAVFN----K----------------------------------------------
AlphaK1_Mmus     SNGGTDVFN----K----------------------------------------------
AlphaK2_Mmus     -------TAPSLPLENVGSGSRVREAAGGVGCFEAGDQETCYATMDLLVGAPVDKYLPQE
AlphaK3_Mmus     -------SLSSLPGALKGSPSGCPRESQAIECFEKSTEAPCVQERSDLMLRS--------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  --------PA------------------------------------------ATKVVEGY
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         -------------SLNNSCNGNNNL-----------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     ICSVDTELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTF
AlphaK3_Hsap     -----------------------------------EEAVVTAS-RNHEQTVLGPLSGN--
AlphaK1_Hsap     -------------SLS--------------------------------------------
AlphaK1_Mmus     -------------SLR--------------------------------------------
AlphaK2_Mmus     ICPEDLELTEGQSEVCDLCS-PDKILAV-LQTQGSEPPRSTDKRSQDGKSAEGLLFNSTF
AlphaK3_Mmus     -----------------------------------EEA---AF-RSHEDGLLGPPSGN--
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ACLLGR------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         --------------------------N---------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     TLNISHTASEGATGENLAKVENSTYPLASTV--------------------HAGQEQPSP
AlphaK3_Hsap     ----------------------------LMLPAQPPHEGSVEQVGGERCRGPQSSG----
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     TWDTAKEASEDAVGETAADVENPPSTFSSTL----------------------------P
AlphaK3_Mmus     ----------------------------RTYPTQLPPEGHSEHLGGQ--------T----
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         -----------------------NGMLNFSNLNIGG--------STSSACSTNSSSNITI
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     SNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEKP-----
AlphaK3_Hsap     ------------------------------------------------------------
AlphaK1_Hsap     --------------------------------------------GSQTSSAWSNL-----
AlphaK1_Mmus     --------------------------------------------DNSSSCSWGRL-----
AlphaK2_Mmus     YSERGFGETQPLCSETISFVKDSEGSYRSSSLSIPAAIDTLASYSSDRECSKEQS-----
AlphaK3_Mmus     ------------------------------------------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  --------------------------------------------------THNRL-----
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ANNINSSNNINIINNQNNQNNNNNNNTNNVMISPSPSPNPF-------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     ------------------------------TTLTAN-----NECFQATRETEDTSTVTIA
AlphaK3_Hsap     ------------------------------------------------------------
AlphaK1_Hsap     ------------------------------SGFS-----SSASWEEVNYHVDDRSARKEP
AlphaK1_Mmus     ------------------------------SGLS-----SSTSWEEVNCAVQDVVRKGSG
AlphaK2_Mmus     ------------------------------AESTAN-----VDCHQVTREMEGIST--NA
AlphaK3_Mmus     ------------------------------------------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------LKLSPDTERNEPSWEEVTVHLQEGTNKAV-
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  -----------------------------------------------------------G


ak1_Ddis         ------------------------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     TEVHPAKYLAVSIPEDKHAGGT-EERFPRASHEKVS-QFPS-QV-QLDHILSGATIKSTK
AlphaK3_Hsap     --------------------------PVEAKQEDSPFQCPKEERPGGVPCMDQGGCPLAG
AlphaK1_Hsap     GKEHLV----------------------DTQCSTALSEELENDRE---------------
AlphaK1_Mmus     QEEHPV----------------------EAQSSEAASEEPKRNRS---------------
AlphaK2_Mmus     AEVHEIKCHSVSVPQDNDFDVGADQVSCEARDEDNSQSLPDDDS-QSGRSLSSSTGEATG
AlphaK3_Mmus     --------------------------HQRSEQEDSLSQCPKKEQPQEPLHVGLSGGHSTG
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  --PRPVKRLNLKIVKLFDFRQG-KYLPGAPFHADNT-EYPD-DT-PMATVLE--------
CC1G_12594_Ccin  --PRPVKRLNLKIVKLFDFRQG-KYLPGAPFHADNT-EYPD-DT-PMATVLE--------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  VVSKPVKLLNISIQKMTDYDGG-KYRSGPVFHAWQR-RYPE-DT-PMDEVFN--------


ak1_Ddis         ----LP-TPTSTNQNNH-IITPIPVNPFTD-NLQLNSNNIRQHPQ-QMYIQQQQQQQQQQ
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     EL-LCR-APSVPGVPHHVLQLPEGEGFCSNSPLQVDNLSGDKS-QTVDRADFRSYEENFQ
AlphaK3_Hsap     LSQEVP-TMPSLPGT--GLTASPKAGPCSTP-----------------------------
AlphaK1_Hsap     -GRAMHSLHSQLHDL--SLQEPNNDNLEPSQ-----------------------------
AlphaK1_Mmus     -SRAVY-LSSKLRGV--SLQTTGDDNLESSP-----------------------------
AlphaK2_Mmus     ET-LVP-APSSAGDHGH-FSMPEGQGLCSR-ALQMDNQPVCQS-QAMEGAHSRGLEEHFQ
AlphaK3_Mmus     LSQEVP-AMPSLPGT--GLTSSLQEELPGTA-----------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  --------------------------------------------------SIDHFD----
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  -VKNKH-IPDGWM-------SATL------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         QQQQQQQQQQQQQQQQQQL-QMQQQ---QQQQMQQHYQQQ-QQQQQQQQQQQQQQQQQQQ
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     ERGSETKQGVQQQSLSQQG-SLSAP---DFQQSLPTTSAA-QEERN--------------
AlphaK3_Hsap     -------TSQ---HGSTAT-FLPSE---D-QVLMSSAPTL-HLGLG--------------
AlphaK1_Hsap     -------NQP---QQQMPLTPFSPHNTPG-IFLA--------------------------
AlphaK1_Mmus     -------SQL---HNHTSILPFNAK---D-TCLA--------------------------
AlphaK2_Mmus     EKGSGMKHGIRPQSTSHQV-SLSAN---DFQEILPSIPTM-QQETN--------------
AlphaK3_Mmus     -------ASL---HTNTDV-PLPSR---D-QDFPSSAPTL-QLGPG--------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ----------------------------KNDSILALFNYL-VQENF--------------
CC1G_08873_Ccin  -----------------------------------DIRTKVDNA----------------
CC1G_12594_Ccin  -----------------------------------DIRTKVDNA----------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  -----------------------------------DVFHLVVNTY---------------


ak1_Ddis         QQQQQQQQQQQQQQQQQQQQQ---------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     --------------------LVPTAH---SPASSREGAGQRSGWGTRVSVVAETAGEEDS
AlphaK3_Hsap     --------------------TPTQSHPPETMATSSE-GACAQVPDVEG------------
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     --------------------VEPLEH---SLADSREEIECSSDPRTSDLVVAEKTVGEDS
AlphaK3_Mmus     --------------------SPTQSHPPEAMATSSE-GACAKEPNVDG------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  --------------------LKPSQ-----VADRHIEIWFAFD-----------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ------------------------------------------------------------
10338_Tthe       -----------------------------------------QLIWQQATVYA--------
AlphaK2_Hsap     QALSNVPSLSDILLEESKEYRPGNWEAGNKLKIITLEASASEIWPPRQLTNSESKASDGG
AlphaK3_Hsap     -------------------------------------------------RTPGPRSCDPG
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     HLVVSVPALPDILLGEKDDVGLGSWAVGGKVKIITLEAPVFEIWPPELVRHPGYKEAEAG
AlphaK3_Mmus     -------------------------------------------------RSSGTRSCDPG
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  -----------------------------------------------EKSDYISGVSEG-
CC1G_08873_Ccin  -------------YKKDRDYRVY-------------DINEFTMLWASARVAVDPSLCTG-
CC1G_12594_Ccin  -------------YKKDRDYRVY-------------DINEFTMLWASARVAVDPSLCTG-
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  -------------IAKPREYRIY-------------DMSEYQILWHRSKTTVESEMCKG-


ak1_Ddis         ------------------------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     LIIPDKVWAVP-------------------------------------------------
AlphaK3_Hsap     LIDSLKNYLLLLLKLSSTETSGAGGESQVGAATGGLVPSATLTPTVEVAGLSPRTSRRIL
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     LTMPGRSWALS-------------------------------------------------
AlphaK3_Mmus     LIDSLKNYLLLLLKLSSPETSEARAESQEVADTGGLTSSSTLVPTMEVAGLSPRTSRRIL
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ------------------------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     DSLKADAVVPELAPSEIAALAHSPE-DAESALADSRESHKGEEPTISVHWRSLSSRGFSQ
AlphaK3_Hsap     ERV-------------------------------------------ENNHLVQSAQTLL-
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     DILRAGATRSEPGALGGAAWVPSPQADALMALGANRDTWLGAAPDRQANCNCLSSQCLSQ
AlphaK3_Mmus     ERV-------------------------------------------ENNHLVQSAQTLL-
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  --------------------------------------------LQSAIPLRQSTAKSA-
CC1G_08873_Ccin  --------------------------------------------TLRDLWRACSANSLL-
CC1G_12594_Ccin  --------------------------------------------TLRDLWRACSANSLL-
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ----------------------------------------------EAYKGFCASQNWL-
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  --------------------------------------------TVGDLWHAVSTNSFL-


ak1_Ddis         --------------------------------------------------QHINLSSSA-
10338_Tthe       -----------------RL-----------------------------------------
AlphaK2_Hsap     PRLLESSVDPVD--EKELSVTDSLSAASETGGKENVNNVSQDQEEKQLKMDH-----TAF
AlphaK3_Hsap     -------LSPCT--SRR-------------------------------------------
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     PRFLESSVDPVE--DKELEVTDSPSEVSKTGEMEMPETLNEEQEETQQILRH-----PAV
AlphaK3_Mmus     -------LSPCT--SRR-------------------------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  -------VPPAQ--SKASA-----------------------------------------
CC1G_08873_Ccin  -------VSPAD--VKKSL-----------------------------------------
CC1G_12594_Ccin  -------VSPAD--VKKSL-----------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  -------VPLTGPTARR-------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  -------VPPGD--YKAAA-----------------------------------------


ak1_Ddis         PLQSVNHSP------------------IPLQPQ--HSSSQYMNQQGYQVY----------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     FKKFLTCPKILESSVDPIDEISVIEYTRAGKPEPSETTPQGAREGGQSND---------G
AlphaK3_Hsap     -------------------------------------------------L--------TG
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     VNQSVNFPRILESSVDPIDDRGELEGVWPEKPEPSDSSV----EGNEFIV---------G
AlphaK3_Mmus     -------------------------------------------------L--------TG
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  -------------------------------------------------------PPVTV
CC1G_00657_Ccin  -------------------------------------------------ARVGGLPSMGV
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         PN-----------------------------------VGNQPQSPQQIQPQPL----QQQ
10338_Tthe       -FNKEINIIM------EN--VKAKNCT---------------------------------
AlphaK2_Hsap     NMGHEA--EIQPAILQVPCLQ--GTILS-ENRISRSQEGSMKQEAEQIQPEEA----KTA
AlphaK3_Hsap     LLDREV--QA-------------------------------------------GRQALAA
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     NTCQRV--DIQPASLQLPHPQDSGEIIPYEHTTNQNRVDGERAEAKTSLPDKAKAEAEAV
AlphaK3_Mmus     LLDREV--QA-------------------------------------------GQQALAA
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  -RVLHSRPSAQQVFSRDPPLVEVTFLRVT-------------------------------
CC1G_08873_Ccin  -IEWAV--AVNYDEARND--TDDDDTV---------------------------------
CC1G_12594_Ccin  -IEWAV--AVNYDEARND--TDDDDTV---------------------------------
CC1G_11146_Ccin  NFELFV--LMKMYTKRIE--LSEEDG----------------------------------
CC1G_00657_Ccin  PFELFL--KMNMYYARLE--REGSAA---------------------------I------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  -MVWHV--DVQYDDSREPHIEDVEDVEPKT------------------------------


ak1_Ddis         IFQQVQQQQPQIPQQS-----PQPLQSSTDE---------------DQSVLEVLNL----
10338_Tthe       --------------------------------------------------PEFEL-----
AlphaK2_Hsap     IWQ----------VLQPSEGGERIPSGCS-------------------------------
AlphaK3_Hsap     ARG----------SWGPGPSSLTVPAIVVDEEDP-GLASEGASEGEGEVSPEGPGLLGAS
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     VWQ----------AQGPGEEGQGIPSVCS-------------------------------
AlphaK3_Mmus     AQC----------SRGPCPTPLTIPAIVVGEEGSAGEDSEE----------------RTS
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  --------------------------------------------------PEFQG-----
CC1G_12594_Ccin  --------------------------------------------------PKFKGK----
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  --------------------------------------------------LDQIGV----
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         --------------------------------------------------KK--------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     -------------------------------------------------IG---------
AlphaK3_Hsap     QESSMAGRLGEAGG-QAAPGQGPSAE----------------------SIAQEPSQEEKF
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     -------------------------------------------------MS---------
AlphaK3_Mmus     QESDKKGLLGEV--------EGHTVE----------------------SRTQEPCQEEAM
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  --------------------------------------------------A---------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ---------TKASLFRISY-----TNPNRSLD----------------------------
CC1G_11146_Ccin  ---------------RPSG-----KRRDRSEYLVAYSTGHGPSKIARQQ-----------
CC1G_00657_Ccin  ---------GSSSLVRPSA-----NKRARAG-----------------T-----------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ---------------LFDMN----------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     ------------------------------QIQESSDGSLGEAEQSKKDKAELISPTSPL
AlphaK3_Hsap     PGEALTGLPAATPEELALGAR---RKRFLPKVRAAGD---GEATTPEERESPTVSPRGPR
AlphaK1_Hsap     --PG----AGLLEG-APE--GIQEVRNMG-------------------------------
AlphaK1_Mmus     --SG----AGLVET-A-----------EG-------------------------------
AlphaK2_Mmus     ------------------------------QTQDGGDRSLGEAGQRGTDETEVISPLSPL
AlphaK3_Mmus     PGEALTGLPAATPEELALGAR---RKRFLPKVRAGSD---GEANKAEERESPTVSPRGPR
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------STENGADISWSQASTLEKTETILVSKNLEA
CC1G_08873_Ccin  --VG----AAALQANTSKGASAKRM-----------------------------------
CC1G_12594_Ccin  --VG----AAALQANTSKGASAKRM-----------------------------------
CC1G_11146_Ccin  ---------NPIQSSFSL-PPAGTMRT-VPT-----------------------------
CC1G_00657_Ccin  ------------SS----NVS---LISKIPR---YSC---VPV---------SSFS----
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         -------------------------MMDKEEFEHRRRQIIDNLTKTTSPIHQQP--PQPP
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     SSCLPIMTHASLGVDTHNSTGQIHDVPENDIVEPRKRQYVFPVSQKRGTIENERGKPLPS
AlphaK3_Hsap     KSLVPGS-----------------------------------------------------
AlphaK1_Hsap     ----------------------------------------PRNTSA--------------
AlphaK1_Mmus     ----------------------------------------SSNTSL--------------
AlphaK2_Mmus     SSCLTGVTHTCVKAETNNSTGHIYGG-----SEPRTRQSVIPMKTEKGTIESKCGNHVRS
AlphaK3_Mmus     KGLTPGS-----------------------------------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  NSTNPGF----------------------IG-----------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  -----------------------------QIVPRSKRANSVASTALRTQIESRSG-----


ak1_Ddis         QPV---LP---------------------VSAPAQVPQPHPPQQQNGPTVPQQQQQQQQQ
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     SPDLTRFPCTSSPEGNVTDFLISHKMEEPKIEVLQIGETKPPSSSSSSAKTLAFISGERE
AlphaK3_Hsap     ------------------------------------------------------------
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     SDDLTNTPCTSSPKGNVTRLSISHGLEELKSEKLQIAETKPLNSSDSPTMTLALISGECE
AlphaK3_Mmus     ------------------------------------------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         Q----------------QQQQQQQQQQQQQQQPIPQPSSSSPTP--DARLTGTERVIRHR
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     LEKAPK--LLQDPCQKG-TLGCAKKSR-EREKSLEARAGKSPGT--LTAVTGSEEVKRKP
AlphaK3_Hsap     ------------------PGTPGRERRSPT-----QGRKASM-----------LEVPRAE
AlphaK1_Hsap     -------------------------------HSRPSYRS---------------------
AlphaK1_Mmus     -------------------------------QSSHSCGS---------------------
AlphaK2_Mmus     SEKDPKSLLRRDPCPKGSTLDSGKKSRDQQQKPVAAQVSKAPGD--QSAMAGSEEGKKKQ
AlphaK3_Mmus     ------------------PGTPGRERRSPT-----QARKASM-----------LEVPGAE
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------RTIIPSGRNAYVTRLGVAQSTGIVHIVL--
CC1G_12594_Ccin  ------------------------------RTIIPSGRNAYVTRLGVAQSTGIVHIVL--
CC1G_11146_Ccin  ------------------------------------STKAKF-----------QQS----
CC1G_00657_Ccin  -----------------------------------GAHTSFS-----------TKK----
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ----------------------------KKPRLLPAGKDAYVTR--VVNPSGTSYTVI--


ak1_Ddis         FD-------AKLGKWV-QT------------A--------TI------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     EAPGSGHLAEG--------VKKKILSRVAALR--------LKLEEKENIRKNSAFLKKMP
AlphaK3_Hsap     EELAAGDLGPS--------PKAG-------------------------------------
AlphaK1_Hsap     ------------ASWS-SD------------SGRPKNMGTHPSVQKEE------------
AlphaK1_Mmus     ------------DSWSLSS------------SDRFTDVTTNPSVQEEE------------
AlphaK2_Mmus     EASGSGHLTAG--------IKKKILSRVAALR--------LRLEEKENSRKNS-IVKKTP
AlphaK3_Mmus     EEPATGDLVSR--------SKDS-------------------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ---------KGYWTWV-ED------------S--------AVWVEEQE------------
CC1G_12594_Ccin  ---------KGYWTWV-ED------------S--------AVWVEEQE------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ---------KGAWKFG-KGT-----------S--------VIWVEEEDV-----------


ak1_Ddis         ----------------------------------VI------------------------
10338_Tthe       ---------------FINQHYRRIVMPQPQI---IQIEK---------------------
AlphaK2_Hsap     KLETSLSHTEEKQD--PKKPSCKREGRAPVLLKKIQAEM-------------------FP
AlphaK3_Hsap     GLDTEVALDEGKQETLAKPRKAKDLLKAPQVIRKIRVEQ-------------------FP
AlphaK1_Hsap     -------------------------------AFEIIVEFPETNCDVKDRQGKEQGEEISE
AlphaK1_Mmus     -------------------------------PSGIMGDVPESKYDCKDWHGEKNGGTLAE
AlphaK2_Mmus     KFERSLSRTDEKRD--PKRAPCKAEGKAPVLLKRIQAEM-------------------AP
AlphaK3_Mmus     GLDSEPAVDEGKQEALAKQRKAKDLLKAPQVIRKIRVEQ-------------------FP
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  -------------------------------PFKVVVDK-------------------ES
CC1G_12594_Ccin  -------------------------------PFKVVVDK-------------------ES
CC1G_11146_Ccin  --------------------------------------C-------------------CV
CC1G_00657_Ccin  --------------------------------------L-------------------VT
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  -------------------------------KLKVIVEK-------------------TP


ak1_Ddis         --------------------------------------------------T---------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     EHSG-----------NVK-LSC-Q-FAE---IHEDSTICWTKDSKSIAQV-QRSA-GDNS
AlphaK3_Hsap     DASG-----------SLK-LWC-Q-FFN---ILSDSVLTWAKDQRPVGEV-GRSA-GDEG
AlphaK1_Hsap     RGAGPTFKASPSWVDPEG-ETA-ES---TE------------------------------
AlphaK1_Mmus     ICTGPELTSAPSSVDPEG-ETA-ES---TD------------------------------
AlphaK2_Mmus     EHSG-----------NIK-LSC-Q-FSE---IHEDSTVCWTKDSKSIAQA-KKSA-GDNS
AlphaK3_Mmus     DSSG-----------SLK-LWC-Q-FFN---IVSDSVLTWAKDQHPVGEV-NRSA-GDEG
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  --KGTSKYAYYGRM--------------------ATSTGWKEYA----------------
CC1G_08873_Ccin  FASGVTKKAVKMYIDKKK-YAA-KYFY---------------------------------
CC1G_12594_Ccin  FASGVTKKAVKMYIDKKK-YAA-KYFY---------------------------------
CC1G_11146_Ccin  QLTP-----------LGD-PVIQN-ERMITGFISD---VHV-AQGSMKVVHEKDAGLRRG
CC1G_00657_Ccin  RTKV-----------EVQRITC-K-VLN---NQGDPA---FEKKEKLDLYISDAF-FASG
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  FASGVTKKAHKAYIGTEK-IAA-KYFYD---IHDGS------------------------


ak1_Ddis         ------------------------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     TVSFAIVQASPKD----QGLYYCC----------------IKNSYGKVT-----------
AlphaK3_Hsap     PAALAIVQASPVD----CGVYRCT----------------IHNEHGSAS-----------
AlphaK1_Hsap     -------------DAPLDFHRVLHNSLGNISMLPCSSFTPNWPVQNPDSRKSGGPVAEQG
AlphaK1_Mmus     -------------DGLSPSQVALGCLEGSHSMSTRRTFFPDGSVQNADSAKTGCSVRDQT
AlphaK2_Mmus     SVSLAIVQAGQKD----QGLYYCC----------------LKNSYGKVT-----------
AlphaK3_Mmus     PAALAIVQASPTD----CGVYRCT----------------IQNEHGSAS-----------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ---------------------------------------------VAVL-----------
CC1G_08873_Ccin  -----------------------D----------------IDG-SGAV------------
CC1G_12594_Ccin  -----------------------D----------------IDG-SGAV------------
CC1G_11146_Ccin  SSK-------------------------------------------SERAKT--------
CC1G_00657_Ccin  TMKVVFDASIPDYDSPLIVKRFFK----------------IDNLSSPELDKSGTP-----
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ---------------------------------------------SSVL-----------


ak1_Ddis         ------------------------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     ------------------------------------------------------------
AlphaK3_Hsap     ------------------------------------------------------------
AlphaK1_Hsap     IDPDASTVDEEGQLLDSMDVPCTNGHGSHRLCILRQPPGQRAETPNSSVSGNILFPVLSE
AlphaK1_Mmus     VDPDASTVDEEGQMLDSTEICSIGQDGAHRPRALRS--GQSAEGPKSFVNGSSPSPIFDE
AlphaK2_Mmus     ------------------------------------------------------------
AlphaK3_Mmus     ------------------------------------------------------------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ------------------------------------------------------------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     -------------------------------------------------------AEFN-
AlphaK3_Hsap     -------------------------------------------------------TDFC-
AlphaK1_Hsap     DCTTTEEGNQPGNMLNCSQNSSSSSVWWLKSPAFSSGSSEGDSPWSYLNSSGSSWVS---
AlphaK1_Mmus     DFSTTEEGEELGSMLKSSQNSSSYSPWWLKSPAFSRSSSDGESSWSLLNSSRSSFAS---
AlphaK2_Mmus     -------------------------------------------------------AEFN-
AlphaK3_Mmus     -------------------------------------------------------TDFC-
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  -------------------------------------------------------QDQQL
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  -------------------------------------------N------------WKA-
CC1G_00657_Ccin  ----------------------------------------PKAE-----------FDVL-
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  -------------------------------------------------------PEEN-


ak1_Ddis         ------------------------------------------------E-----------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     LTAEVLKQLSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRLRGQIATE-----------
AlphaK3_Hsap     LSPEVLSGFISREEGEVGEEIEMTPMVFAKGLADSGCWGDKLFGRLVSE-----------
AlphaK1_Hsap     --------LPGKMRKEILEARTLQPDDFEKLLA--GVRHDWLFQRLENTGVFKPSQLHRA
AlphaK1_Mmus     --------LAGQTSQEILEARTLQPDDLEKLLA--GVRHDWLLQRLENTGVLKSNQLQQA
AlphaK2_Mmus     LTAEVLKQLSSHTEYRGCEEIEFSQLIFKEDVFNDSYFGDHLRGQISTE-----------
AlphaK3_Mmus     LSPEVLSGFISREEGEVGEEIEMTPMVFAKGLADSGCWGDKLFGRLVSE-----------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  SP----------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  VRN--------------------------------------------LS-----------
CC1G_00657_Ccin  THNSLIR----------------------------------------AE-----------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  LR----------------------------------------------------------


ak1_Ddis         ---------------------------PTPFAEG--AMRKAFRMKDLSA-----------
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     ---------------------------ELHFGEG--VHRKAFRSTVMHGLMPVFKPGHAC
AlphaK3_Hsap     ---------------------------ELRGGGYGCGLRKASQAKVIYGLEPIFESGRTC
AlphaK1_Hsap     HSALLLKYSKKSELWTAQETIVYLGDYLTVKKKG--RQRNAFWVHHLHQ-----------
AlphaK1_Mmus     HSALLLKYSKKSELWTAQETVVYLGDYLKVKKKG--KQRNAFWVHYLHQ-----------
AlphaK2_Mmus     ---------------------------ELHFGEG--VHRKAFRSKVMQGLMPVFQPGHAC
AlphaK3_Mmus     ---------------------------ELRGGGH--GLQKASRAKVIYGLEPIFESGRTC
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ---------------------------LARG-------KA--------MLELFYERCE--
CC1G_00657_Ccin  ---------------------------GVRAG----LGQR--------LLNSFYRDAE--
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------------------------------------------------------


ak1_Ddis         ---------EGPS--SQMVAKLFKDSNEDRMVYFKDV--EMQTYSKEIAERFNL-K---S
10338_Tthe       ---------KSLL--ASLLGKHYKE-----------------------------------
AlphaK2_Hsap     VLKVHNAIAYGTRNNDELIQRNYK-------LAAQEC--YVQNTARYYAKIYAA-E---A
AlphaK3_Hsap     IIKVSSLLVFGPSSETSLVGRNYD-------VTIQGC--KIQNMSREYCKIFAA-E---A
AlphaK1_Hsap     ---------EEIL--GRYVGKDYKEQKG-LWHHFTDV--ERQMTAQHYVTEFNKRLYEQN
AlphaK1_Mmus     ---------EETL--GRYVGKEYKERKG-LRHHFTDV--ERQMTAQHYVTEFNKRLYEQK
AlphaK2_Mmus     VLKVHNAVAHGTRNNDELVQRNYK-------LAAQEC--YVQNTARYYAKIYAA-E---A
AlphaK3_Mmus     IIKVSSLLVFGPSSETSLLGRNYD-------VTIQGC--KIQNMSREYCKIFAA-E---A
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  ------------HNARLLL--------------------RAEYVLMCKGQYFKQ-AFDQL
CC1G_08873_Ccin  -------------------------SHKDNLVHLKDELLRGHILEVAAEKFVKS-ARHAK
CC1G_12594_Ccin  -------------------------SHKDNLVHLKDELLRGHILEVAAEKFVKS-ARHAK
CC1G_11146_Ccin  EKGVDAYLYLSFAKGLLLQE----------------------------------------
CC1G_00657_Ccin  QADVNVYKYFFFEIPTFYQE----------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  ------------CLKDELL--------------------RLQMLGRSIVKFLSI-SKQER


ak1_Ddis         ---------PPKKIDFVPA-FVMELVE--R-------Q-----GKPFCAVEYF------I
10338_Tthe       --------------------------------------G------DLISLESY------L
AlphaK2_Hsap     QPLEGFGEV--------PEIIPIFLIHRPE-------N-----NIPYATVEEE------L
AlphaK3_Hsap     RAAPGFGEV--------PEIIPLYLIYRPA-------N-----NIPYATLEEDLGKPL-E
AlphaK1_Hsap     IPTQIF---------YIPS-TILLILED-K-------T-----IKGCISVEPY------I
AlphaK1_Mmus     IPTQIF---------YIPS-TILLILED-R-------T-----IKGCISVEPY------I
AlphaK2_Mmus     QPLEGFGEV--------PEIIPIFLIHRPE-------N-----NIPYATVEEE------L
AlphaK3_Mmus     RAASGFGEV--------PEIIPLYLIYRPA-------N-----NIPYATLEEDLGKPL-Q
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  AQDLNV-KIPNFCFDF-KEAIFGSLIPKPD-------TQAHLPHHWFLATPLLRCGP--F
CC1G_08873_Ccin  ISTYDI-RGPAE-------SFILTVVEGPS-------K-----GRAWLVDPL------FE
CC1G_12594_Ccin  ISTYDI-RGPAE-------SFILTVVEGPS-------K-----GRAWLVDPL------FE
CC1G_11146_Ccin  IGKHSPASG--------QLCD----SET--DHDGQEVI-----GIKW------LAEERHL
CC1G_00657_Ccin  ISKPSPASG--------VVSDELF--GVPSESEVE-EN-----LILW------CGERKHP
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  VSVYNL-RV--------PESYVLRTVE--G-------E-----DHAWLADPLF------E


ak1_Ddis         EGKYEKHNNN-----F-GYKNDYDRNTPQAFSHFSYEDSGCQLIVVDIQGVGD-------
10338_Tthe       EGEYRKFNSNS-------GWSDESYPLMQAFSHFTFYNSGGQEILCDLQGIDEID-----
AlphaK2_Hsap     IGEFVKYSIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGM-------
AlphaK3_Hsap     SYCSREWGCAE---APTASGSSEAMQKCQTFQHWLYQWTNGSFLVTDLAGVDW-------
AlphaK1_Hsap     LGEFVKLSNNT---KV-VKTEYKATEYGLAYGHFSYEFSNHRDVVVDLQGWVTG------
AlphaK1_Mmus     LGEFVKLSNNT---KA-VKNEYKATEYGLAYGHFSYEFSNHRDVVVDLQGWVTG------
AlphaK2_Mmus     IGEFVKYSIRDGKEINFLRRDSEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGM-------
AlphaK3_Mmus     TYCSRQWGCAG---APAAASSSEALQKCQTFQHWLYQWTNGSFLVTDLTGADW-------
CC1G_14582_Ccin  ------------------------------------------------------------
CC1G_06337_Ccin  ------------------------------------------------------------
CC1G_14302_Ccin  DPPFRKFTGND---EMGP-PEDAITAAVHAFAHFSYVYSGGDLVFCDLQGGRDSS-----
CC1G_08873_Ccin  NAVMRKFSGTD---LA-GANSDLAGRTCDAFAHFSLDDSDGSVVFVDIQGIDSSTLPITS
CC1G_12594_Ccin  NAVMRKFSGTD---LA-GANSDLAGRTCDAFAHFSLDDSDGSVVFVDIQGIDSSTLPITS
CC1G_11146_Ccin  SRRIVRFCGTM---QHQTTRTDLAYQTVHTFNHFVYLHTNRQLIFADLQGTPTSVK-LAS
CC1G_00657_Ccin  SEVVIRFNGTL---SHPSTRTDMKHLTMYAFCHYVYGVTKGTLVFADIQGTPATLT-QG-
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  GAEVQKFSGTS---QAGSNSESLVGQTCDALAHFSFHDSEGSIVFVDIQGFDSASLPMSS


ak1_Ddis         ----------VYTDPQIHSADGQGF--G-KGNLGI-EGIKRFF-STH----QCNPICHYL
10338_Tthe       ------SKTIQLTDPAILSIR-SRF--G-DSDIGY-KKLQYWI-KNH----KCNHICHAL
AlphaK2_Hsap     ----------KLTDVGIATLA-KGYK-GFKGNCSM-TFIDQFK-ALH----QCNKYCKML
AlphaK3_Hsap     ----------KMTDVQIATKLRGYQ--G-LKESCFPALLDRFA-SSH----QCNAYCELL
AlphaK1_Hsap     ----NGKGLIYLTDPQIHSVD-QKV--F-TTNFGK-RGIFYFFNNQH---VECNEICHRL
AlphaK1_Mmus     ----NGKGLIYLTDPQIHSVD-QKD--V-TTNFGK-RGIFYFFNNQH---ASCNEICHRL
AlphaK2_Mmus     ----------KLTDVGIATLA-RGYK-GFKGNCSM-TFIDQFR-ALH----QCNKYCKML
AlphaK3_Mmus     ----------KMTDVQIATKLRGYQ--G-LKESCFPALLDQFA-SSH----QCNTYCDML
CC1G_14582_Ccin  ---RAAVHALTLFDVVIHSDD-ESY--G-LGGQGT-SGLEELA-ARH----QCNNICKAL
CC1G_06337_Ccin  ---RAAVHALTLFDVVIHSDD-ESY--G-LGGQGT-SGLEELA-ARH----QCNNICKAL
CC1G_14302_Ccin  -------GRVCLVDPQCHTLS-KAKDSPVYWDGGP-SKIKIVI-DKHLQDCSQNQYCNAL
CC1G_08873_Ccin  GIPLNVAHSVTLFDVMIHSSD-GVY--G-LGDQGW-TGIRDFV-TQH----KCNTICAKL
CC1G_12594_Ccin  GIPLNVAHSVTLFDVMIHSSD-GVY--G-LGDQGW-TGIRDFV-TQH----KCNTICAKL
CC1G_11146_Ccin  ---GEVVEGMMLFDPMTHTIN-HGS--G-IGDFGQ-EGIDTFV-EQH----TCGPLCRAL
CC1G_00657_Ccin  ---NQDKDGYLLFDVMTHTEH-KAS--G-IGDFGQ-EGINRFV-EEH----VCQEVCLLL
CC1G_02529_Ccin  -----------------HTEH-KAS--G-IGDFGE-EGINKFV-EEH----VCQEVCLLL
CC1G_10953_Ccin  -----------------HTEH-KAS--G-IGDFGE-EGINKFV-EEH----VCQEVCLLL
CC1G_07428_Ccin  RQGRTAAHALTLFDVMIHSVE-KSY--G-LGDQGT-SGLEDFV-SQH----RCNSICKAL
                                   :                   :       *         *  *

ak1_Ddis         GLSSVNPKPAND-ES-GTMPR-----PPSIGQSYVRPSAFPPNLQQSFSF----NFPPLK
10338_Tthe       KLDDFKLEESLI-YSKSCNNVQQ-------------------------------------
AlphaK2_Hsap     GLKSLQNNNQKQ-K------------QPSIG----------------------------K
AlphaK3_Hsap     GLTPLKGPEAAHPQAKAKGSK-----SPSAGRKGSQLS---------PQPQKKGLPSPQG
AlphaK1_Hsap     SLTRPS------------------------------------------------------
AlphaK1_Mmus     SLTRPS------------------------------------------------------
AlphaK2_Mmus     GLKSLQNNSQKP-K------------KPIVG----------------KGR----VPT---
AlphaK3_Mmus     GLKPLKGPEAAHPQAKAKGSK-----SPSAGRKGSQLS---------PQPQKKGLPSPQG
CC1G_14582_Ccin  GLPDAKEFCKDL-TVKAGEWEALSVSVPNVD-----LD---------PRR----SPSPVT
CC1G_06337_Ccin  GLPDAKEFCKDL-TVKAGEWEALSVSVPNVD-----LD---------PRR----SPSPVT
CC1G_14302_Ccin  GLKFLQYTADDP-FEEPGHQGQDDPASPSRP-----KK---------KRR----TASPRG
CC1G_08873_Ccin  GLRDVRELWDEY-HADE---------HPALEDK---------------NN----KP----
CC1G_12594_Ccin  GLRDVRELWDEY-HADE-------------------------------------------
CC1G_11146_Ccin  HLLDSDGSDVNAPKA----T----------------------------------------
CC1G_00657_Ccin  GFDKQFPLAPVAS--DEQES----------------------------------------
CC1G_02529_Ccin  GFDKQFPLTPVTS--YEKYS----------------------------------------
CC1G_10953_Ccin  GFDKQFPLAPVTL--YEKYS----------------------------------------
CC1G_07428_Ccin  GLTDVTDIWKEV-TAELSDWEAQSMSVPDVD-----LA---------PKR----SPSPVP
                  :

ak1_Ddis         DHHVLEQLNQQQQHLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNQQQ
10338_Tthe       ------------------------------------------------------------
AlphaK2_Hsap     SKV---------------------------------------------------------
AlphaK3_Hsap     TRKS--------------------------------------------------------
AlphaK1_Hsap     ------------------------------------------------------------
AlphaK1_Mmus     ------------------------------------------------------------
AlphaK2_Mmus     ------------------------------------------------------------
AlphaK3_Mmus     SRKS--------------------------------------------------------
CC1G_14582_Ccin  SDNG--------------------------------------------------------
CC1G_06337_Ccin  SDNG--------------------------------------------------------
CC1G_14302_Ccin  VM----------------------------------------------------------
CC1G_08873_Ccin  ------------------------------------------------------------
CC1G_12594_Ccin  ------------------------------------------------------------
CC1G_11146_Ccin  ------------------------------------------------------------
CC1G_00657_Ccin  ------------------------------------------------------------
CC1G_02529_Ccin  ------------------------------------------------------------
CC1G_10953_Ccin  ------------------------------------------------------------
CC1G_07428_Ccin  SDKG--------------------------------------------------------


ak1_Ddis         NQQQNQQQQQQQQQQQ-------QQQQNGHPPPQTPLPPTPQQKDKPKIEVFGDILRKLV
10338_Tthe       ------------------------------ETWLTN-----------------LYPSKTK
AlphaK2_Hsap     -----------------------QTNSMTIKKA-GP-----------------ETPGEKK
AlphaK3_Hsap     -AP-SSKATPQASEPV-------TTQLLGQPPTQEE-----------------GSKAQGM
AlphaK1_Hsap     -------------------------------------------------------MEKPC
AlphaK1_Mmus     ------------------------------------------------------LEQTSK
AlphaK2_Mmus     -------------------------NATQVK-TPES----------------ETPPAERK
AlphaK3_Mmus     -AP-SSRATLQASQAA-------TVQLLGQPPVQDG-----------------SSKAQSM
CC1G_14582_Ccin  -----------------------CSALTSLKHYGES-----------------DSSDSEE
CC1G_06337_Ccin  -----------------------CSALTSLKHYGES-----------------DSSDSEE
CC1G_14302_Ccin  -----------------------------------------------------AINSLLT
CC1G_08873_Ccin  ----NADTTYDLDDVDRLEMENDPDADLDQDGVG-D-----------------DRTTAGD
CC1G_12594_Ccin  -----------------------------------------------------HPALEHK
CC1G_11146_Ccin  -------------------------------DTEES-----------------EDEAQDN
CC1G_00657_Ccin  -----------------------ESEEEGS-------------------------DPTNR
CC1G_02529_Ccin  -----------------------ESEEEGSDPTNRT-----------------SKLASDF
CC1G_10953_Ccin  -----------------------KSEEEGSDPTNRT-----------------SKLASDF
CC1G_07428_Ccin  -----------------------HSGLTGLNQYG-------------------ESESSEE


ak1_Ddis         S
10338_Tthe       C
AlphaK2_Hsap     T
AlphaK3_Hsap     R
AlphaK1_Hsap     T
AlphaK1_Mmus     V
AlphaK2_Mmus     T
AlphaK3_Mmus     R
CC1G_14582_Ccin  D
CC1G_06337_Ccin  D
CC1G_14302_Ccin  S
CC1G_08873_Ccin  N
CC1G_12594_Ccin  T
CC1G_11146_Ccin  D
CC1G_00657_Ccin  T
CC1G_02529_Ccin  I
CC1G_10953_Ccin  I
CC1G_07428_Ccin  D