ADCK2_Mmus MVTPWRLSV-R---VCLSHLR-----CFEF-----R-K-------------ELGHSRPLG
Y32H12A.7_Cele MIFGSTRLILY---RCWAHSR-----AVSS-----R-NFKLGIVLGMGGAVSLTRLRTLK
YPL109C_Scer MGLYVSSEN-E---LQ----------------------------------EKLKSFRSAK
ADCK2_Hsap MVAPWRVSV-R---VCLSHLR-----CFEL-----R-Q-------------GLSLLRPSE
AdckC_Ddis MSNKQIFLKFKSGEIILNNFN-----KYTD---SIS--------------SKLLFYQNIK
ADCK2_Spur MFIHHISRI-T---LQLRRVR-----PLH-------------------------------
CC1G_01824_Ccin ------------------------------------------------------------
AqueK030_Aque MVGTSCSAVIG---S----------------------------------MLILNNNRSVH
ABC1-C-1_Smoe MLFFGRTLS-N---SSFSRIGYGHHHYGTLSQEAAASP-----------LQVLSRNLARH
ABC1-C-2_Smoe MA----------------------------------------------------------
ADCK2_Mmus -----------------------------------------------------------C
Y32H12A.7_Cele -----------------------------------------------------------C
YPL109C_Scer -----------------------------------------------------------I
ADCK2_Hsap -----------------------------------------------------------C
AdckC_Ddis NQENNSGN------------------ENYKNFNYNYKNKNNYNNNNNNNNSNSSSNNNGS
ADCK2_Spur ------------------------------------------------------------
CC1G_01824_Ccin ------------------------------------------------------------
AqueK030_Aque -----------------------------------------------------------C
ABC1-C-1_Smoe -----GGNRIVFGFSRTGVEFKDGWKK---------------------KGTGFAGWKLGS
ABC1-C-2_Smoe ------------------------------------------------------------
ADCK2_Mmus SRNA-------------RLCWFLLGTLPKL---------------I--------SAHGSV
Y32H12A.7_Cele EAEH-------------QDPWLLVPQK---------------------------------
YPL109C_Scer TE----------------------------------------------------------
ADCK2_Hsap PRDA-------------RLCWLLLGTLPKV---------------V--------SLCGDV
AdckC_Ddis NNNI-------------KFNSLFISSIYLYNNNNSNNNDLKNDKN-------------DN
ADCK2_Spur --------------------WTVLKRLPQP-----KYHPTKSVALT--------VCCAFI
CC1G_01824_Ccin ------------------------------------------------------------
AqueK030_Aque IES---------------------------------------------------------
ABC1-C-1_Smoe STGRAWKNSWLGRCYYHHPLWKVVGTMSLA---------------VVRSQFSPRIAAFLV
ABC1-C-2_Smoe ------------------------------------------------------------
ADCK2_Mmus GEGA----PGSLCQRKTHWSDLAENGLV------EKVAQ---------------E-GPLA
Y32H12A.7_Cele -----------------------------------KVVVEKSTMMGIITLP--IT--LIV
YPL109C_Scer ---------------------------------------SRNKLIRYLRIFW---FGFND
ADCK2_Hsap GEGA----PDVLSRRRVRCSGAAGAGPA------ESLPR---------------A-GPLG
AdckC_Ddis SIGN----INKIIKPKIEIQD----------------------LLNPFEAIKEIVGNKED
ADCK2_Spur GVASYKRLPQILFS-RAACQEAVLDHPVLINSEIDRLHSVKSLLVGQMRLWHHVLRTLAS
CC1G_01824_Ccin ------------------------------------------------------------
AqueK030_Aque -------------------------------------------KSGFIDKP--IV--IPD
ABC1-C-1_Smoe GEA-------TLMRRLVAESEAPTCVPL-----------SYHSDIQPS----YV-LWIFS
ABC1-C-2_Smoe ------------------------------------------------------------
ADCK2_Mmus RVLLCLRLGLRAGVLLAKFFPLLFLYPLTYLAP------------GLSTLWLHLLFKATE
Y32H12A.7_Cele VTYKAIRKMFRCISLFLRFSPILLTYPLTKIE-------------AFENLWWRYLLWSLQ
YPL109C_Scer NIVEPVCTILRFLEISAIFLPLLLLYPISWFGHKLKITDTNITETRGSLIWCQLLRKALE
ADCK2_Hsap GVFLHLRLWLRAGALLVKFFPLLLLYPLTYLAP------------SVSTLWLHLLLKATE
AdckC_Ddis EEINLVKIGIRVLELGLILLPSVLTFPCCFI-P------------GVKELWWQLLLETIQ
ADCK2_Spur NLVQFVLVSLRYIRNSILFGPLLFSYPLVLLFPD-----------RLQDVWLRALLRSIE
CC1G_01824_Ccin ----------------------------------------------------------ME
AqueK030_Aque GSFNRLIVVFRLFYLGLLFSPVLLCHVIEILLPL---------R-FILSLKWSLLLFSIE
ABC1-C-1_Smoe SLVEGMMLLLRALYLVVVFAPALAVAPFADPS-----------DAKLRLFWLELFHSSLE
ABC1-C-2_Smoe KTVEAVLLFFRTLYLFALFTPALVLSMFAADKP----------DSRLRAAWLYVLLRTLE
:
ADCK2_Mmus TSGPTYIKLGQWASTRRDLFSEAFCTQFSKLHVQVTPHPWAR-TEYLLQQAF-GE-DW--
Y32H12A.7_Cele HSGPTFIKLGQWASTRRDIFTKKFCDRLSVLHIQTKNKRFFRDKKKVMNEVF-GK-GFMK
YPL109C_Scer LAGPSFIKLGQWAGSRTDIFSHALCHELGKLHSNVTAHSLSF-TLEKLSQAL-KVDKI--
ADCK2_Hsap TSGPTYIKLGQWASTRRDLFSEAFCAQFSKLHVRVTPHPWTH-TERFLRQAF-GD-DW--
AdckC_Ddis FSGTCWIKFGQWISTRPDLFPDLLIEKFSQLHSQCPSHSFQF-TNESIENSFNGK-SI--
ADCK2_Spur LSGPTFIKLGQWASTRRDLFSQDFCDQLSKLHRNAPSHSVEY-TKRALEHAF-GL-LG--
CC1G_01824_Ccin AAGPTFIKLAQWAASRVDLFPPILCERLGALHSQGTPHPFSH-TKKVVEAVF-QR-PF--
AqueK030_Aque RAGPAFIKLGQWASTRPDIFSESTCAFLSQLQRDCTPHSWDA-TKQTLEDSF-GP-QW--
ABC1-C-1_Smoe RAGAAFIKWGQWAATRPDLFPKDVCETMSKLHSKAPAHSFSQ-TRKTVEGAF-GK-RI--
ABC1-C-2_Smoe YAGPAFIKWGQWAATRPDMFPADICQQLSKLHSQAPAHTFYE-TRKIIEKAF-HL-PL--
:*. :** .** .:* *:*. :. *: : . : :
ADCK2_Mmus ---GSLLFF-ETREPVGSGCVAQVYKAFASISLLEEDRIWRLGELS--APG--TRAVVMQ
Y32H12A.7_Cele LHGKQVFL-EIEPFSIGSGCIAQVYRGTVDISELEKATGKEY------------------
YPL109C_Scer ---EDAFD-EFNRTPIGVGSIAQVYVGELSQKYIDKYDNIQ-------------------
ADCK2_Hsap ---GSILSF-ENREPVGSGCVAQVYKAYANTAFLETDSVQRLGRASCLPPFSHTGAVGGL
AdckC_Ddis ---KDLFL-WFDEEPMASGSVAQVHKALTM-D----------------------------
ADCK2_Spur ---KEIFRLESGNETVYSGCVGQVHKAYMRPDVYQAVM---KGR------------EGGL
CC1G_01824_Ccin ---DQVFE-EFDQTPIGSGAIAQVYRATLKRDLIPPSYHGPR---R-------TRQVGG-
AqueK030_Aque ---EDMFT-RYDHTPIGSGCIAQVYKWDLSTDSMQCSADAAV------------------
ABC1-C-1_Smoe ---EELFE-DFEEEPLASGSVAQVHRAVLRGQ----------------------------
ABC1-C-2_Smoe ---DRLFE-EFSEKPIASGSIAQVHKAVLRTK----------------------------
: .: *.:.**:
ADCK2_Mmus REPF---MKDRKPSENLADEAFLEKLLLPKADLGGSEVGVS--QAPW---HLPKSDHLIP
Y32H12A.7_Cele ---------------------------------------------P-----ELKGRTTQR
YPL109C_Scer ----------------------------------------------------IGKDGNRW
ADCK2_Hsap RELFGYLGNGRKPPENLADQSFLERLLLPKADLVGSNAGVSRAQVPG---HQPEATNLIS
AdckC_Ddis --------------------------------------------------------G-KV
ADCK2_Spur RDWR---MRD-------------------------------RASDP-----IMDEEKWIP
CC1G_01824_Ccin ------------------------------------------ALGPIILEDPPPSAPTAS
AqueK030_Aque ----------------------------------------------------KANGGSLP
ABC1-C-1_Smoe ------------------------------------------------------GKKPVT
ABC1-C-2_Smoe ------------------------------------------------------GQKPLV
ADCK2_Mmus VAVKVLHPGLLSQVSMDLLLMKIGSKALG-LLPGVKWLSLPEIVEEFEKLMVQQTDLRYE
Y32H12A.7_Cele IAIKVADKDVDKQIELDLSILRSGAWLMQHIVPALWYLDPTGALEQFEMVLRRQVDLRNE
YPL109C_Scer CAIKILHPNVRSQIRRDLKIMKFCADAIN-WIPTMEWLSLPSEVDQFSILMNIQLDLRIE
ADCK2_Hsap VAVKVLHPGLLAQVHMDLLLMKIGSRVLG-VLPGIKWLSLPEIVEEFEKLMVQQIDLRYE
AdckC_Ddis AVVKVLHPNVKSNIKRDFFIIYSLIWAFS-HIPEMKWLSLPESILEFGKSMMKQADLELE
ADCK2_Spur VAVKVLHPGIYESVHLDLRIINVFARILN-LIPGLHWLSPVDLVDEFESLMKNQINLKLE
CC1G_01824_Ccin VAIKILHPRVEKTISRDLAIMHFFASCIS-LLPGMKWLSLPEEVLVFGEMMNQQLDLRHE
AqueK030_Aque VAVKVVHPGVVGSVLRDVYLMETVAWFVDRVFPSVYWISLRECVDEFGIVMKKQLDLKAE
ABC1-C-1_Smoe VAVKVRHPGVTEVIRRDFILINWVVKACS-HFSGLRYLRLEDSVQQFAVFMLTQVDLARE
ABC1-C-2_Smoe VAVKVRHPRVSTVIQRDFVIMNWLARMST-KFSSLEHLQLDKTVQQFATFMTKQVDLTLE
.:*: . : : *. :: .. : : : * : * :* *
ADCK2_Mmus AQNLEHFQHNFQDMA-SVKFPTPLRPLITRDILVETYEESVPVSSYQQAG----------
Y32H12A.7_Cele AKALKKFSDNFSSKETGIKFP--IVLGYTKNVIVETFEEGIYINRLVAEEGQPEIFENET
YPL109C_Scer ALNLERFNENFKNSI-QVKFPKPFLPLSNRDVMFEEHVYGLSMEKFLSTKKQIN------
ADCK2_Hsap AQNLEHFQVNFRNVK-AVKFPTPLRPFVTREVLVETYEESVPVSSYQQAG----------
AdckC_Ddis ASHLNRFNSNFKYNS-EVIFPKPLYPLVSKEVLVESFEPGSPIMDFIKKND---------
ADCK2_Spur AENLERFHQNFSKVP-HVRIPQPVWPFVTNEILVETFESGQSISAFISCDPDNP------
CC1G_01824_Ccin ADNLITFEANFAPRKVPVTFPRPLKIWSSKDILVEEYQNALPLETFLRNGGG--------
AqueK030_Aque AVSMDQFRKNFKSHK-HIKIPQPIHTLVTNSVLVETFEEGVHISQYVKESEQ--------
ABC1-C-1_Smoe AAHLSRFLYNFRSWK-DVSFPKPLYPLVHPAVLVETYERGESVSRFVDSPKR--------
ABC1-C-2_Smoe AAHLMRFIYNFRQWR-NVSFPRPIYPLVHPEVLVETFEEGRSIQEFIDEGPR--------
* : * ** : :* . ::.* . . :
ADCK2_Mmus ------------------IPTDLKRKIAQLGINMLLKMIFVDNFVHGDLHPGNILVQGAD
Y32H12A.7_Cele FFRYLFLKIIDFEMLTARQSQAVRRRIALLGARALLKMIFVDNFVHGDLHPGNILIRFND
YPL109C_Scer -------------------DVELCKKVSDPFVDAFLQMLILDDFVHADLHPGNVIIRFVK
ADCK2_Hsap ------------------IPVDLKRKIARLGINMLLKMIFVDNFVHADLHPGNILVQGAN
AdckC_Ddis -------------------H--HNPTLAKIGLSAYMQMMLVDNFVHADLHPGNVLVRTSD
ADCK2_Spur ------------------DEKGIKKILAQMGVDVILKMVFVDNFVHADLHPGNILVQGVE
CC1G_01824_Ccin -------------------P--YDYQIATVGLNAFLTMLLLDNFVHSDLHPGNIMIKFSK
AqueK030_Aque --------------------TSLKKRIASLGIDVLLNMLFVHNFVHCDMHPGNLLVQTDP
ABC1-C-1_Smoe --------------------SHINSALAHIGTHTLLKMLLVDNFIHADLHPGNILVRMER
ABC1-C-2_Smoe --------------------TKLHSQLARLGSSLLLKMLLSDNFIHGDLHPGNMFVKLGK
:: : *:: .:*:* *:****::::
ADCK2_Mmus GVS-PSLEMQ----------QQQVN-----------------VCDTL---------VAT-
Y32H12A.7_Cele NEDNLRGVHK----------APKAD--SALKRG-LE------WFRSLVNLRSAPRIRFT-
YPL109C_Scer TNKYGTNIIS--------SELESYRITHDLRKK-IE----EDQDQDF---------VGK-
ADCK2_Hsap GLS-SSQEAQ----------LQQAD-----------------ICDTL---------VVA-
AdckC_Ddis DDNF-KSIDNNYFKKYNNDN-DQQQ--QQ----QYNLPFKRKLYDTI---------EKSH
ADCK2_Spur EAL-VQPSRT----------VDFHD-----------------HITEF---------QVY-
CC1G_01824_Ccin PPTT-RILLQNLYNHFFPSSVDQST--SDVSSASLMIPADYSQSDEI---------VARL
AqueK030_Aque SVG---------------------------------------------------------
ABC1-C-1_Smoe FNPVPGK-----------------------------------------------------
ABC1-C-2_Smoe ------------------------------------------------------------
ADCK2_Mmus -----------------IAPALCPLRLVLLDAGIVAKLQASDLRNFRAVFQAVVMGQGHR
Y32H12A.7_Cele ----------------DSPDLEDEPTLVLLDTGIAISETPKNLHNLKSLFRSVVEKRGYD
YPL109C_Scer --------------L-KSVLTNYTPQICFIDTGIITELNEKNRINFIALFNALARFDGYR
ADCK2_Hsap -----------------VPSSLCPLRLVLLDAGIVAELQAPDLRNFRAVFMAVVMGQGQR
AdckC_Ddis KKFDSMLGGIQLKSIDFKEHQKSSPKLIFLDVGLVTQLGQQDKDHFIELFTEIVNGNGKE
ADCK2_Spur -----------------LKEPKNPIKLVLLDTGITSHLEERDFNNFYKVFTAIVLRKGDV
CC1G_01824_Ccin RKVSNSPDEWS-RELLKLHSGGYVPEIVFIDAGLVTTLNDTNRTNFLDLFKAVAEFDGYK
AqueK030_Aque --------------------GGGDPSLVLLDCGVTASLNNRDWDNLHQLFLAIVKKEVRD
ABC1-C-1_Smoe ------------------GLFRSHPHLVFLDVGMTAELSNKDRRTLLEFFKGIAMRDGRK
ABC1-C-2_Smoe ----------------------KVPQLILLDVGMTAELSQRNRYILLELFKALSDKDGAR
: ::* *: : : .* :
ADCK2_Mmus VAELMLHHAQANE-CKDVER--FKAEMATLVTQARKNIVTLEKLHVSSLLSSVFKLLMTH
Y32H12A.7_Cele VGKLLLHQSPFQQ-CNDPER--FCRQVEKLVLKARS-EKSLRTLNISALLSEMFTIVAEH
YPL109C_Scer AGELMIERSRTPETAIDKEV--FAFKVEKLVDKVKQRTFTLGTVSIGDLLDQMLSMVRSH
ADCK2_Hsap VAELILHHARASE-CRDVEG--FKTEMAMLVTQARKNTITLEKLHVSSLLSSVFKLLMTH
AdckC_Ddis GAELLIRYAREAK-CTEEEMYQFKERMGTLFNQV--QNSKLSEVHVGQFMSEILGLVREY
ADCK2_Spur VAELFAEHASSNE-CNDVEK--FKADMKSLVEKAHERSLQLSKMQVGQLLRELFALMIHH
CC1G_01824_Ccin TGQLMIERSRTPELAVDKET--FALKMQHLILSIKRKTFSLGQIKIADLLTDVLKNVRKH
AqueK030_Aque ISHAFMH-----------------------------------------------------
ABC1-C-1_Smoe TAECALQFSELQT-CPDPKG--FVREVEDCFKDW--NAMDSAVLHTGDCIQELLERVRRH
ABC1-C-2_Smoe VARCALEFSEDQT-CTNPEA--FIGDVDNTFKQY--LS-VRGTSKMGDYIAELFEQVRRY
.. .
ADCK2_Mmus KVKLESNFASIVVAIMVLEGLGRSLDPTLDILEAAKPFLFKGP-----------------
Y32H12A.7_Cele KVELDSAFTTVILSVMVLEGFGRSLDPDLDLFQCARPFLLN-------------------
YPL109C_Scer HVRMESDFVSVVVAILLLEGIGRQLDPNLDLFERFVFYAWI-N-----------------
ADCK2_Hsap KVKLESNFASIVFAIMVLEGLGRSLDPKLDILEAARPFLLTGP-----------------
AdckC_Ddis HVKIESNFATLVMGTIVLEGLGKQLDPSLGLLKAAIPFLLKSQVFS--------------
ADCK2_Spur KVKLESNFASIILAIMVLEGLGRSLDPNLDILKAAKPVLL--------------------
CC1G_01824_Ccin RVKMEPDFINTVISILLLEGIGRQLDPKMDLFASALPILRQLGGQMAMDTKVEGLPSAKD
AqueK030_Aque ----------LIFVIVYVD--------------------VP-------------------
ABC1-C-1_Smoe KVNIDGDVCTVIVTTLVLEGWQRKLDPEYNIMETLQSLVLQSNMAS--------------
ABC1-C-2_Smoe RVNLDGEVCTVMVTVVILEGWQRKLDMSLDIMRMVKELLFKAEWTA--------------
:. : ::
ADCK2_Mmus ------------------------------------------------------------
Y32H12A.7_Cele ------------------------------------------------------------
YPL109C_Scer ------------------------------------------------------------
ADCK2_Hsap ------------------------------------------------------------
AdckC_Ddis -----------------FSNFIKDFFLKS--KTSKKQLNNDNNNNNNNNNNNKNNNDNNN
ADCK2_Spur ------------------------------------------------------------
CC1G_01824_Ccin LPTSDLAALLKVWVWIEARSFISGALVDMDALI---------------------------
AqueK030_Aque ------------------------------------------------------------
ABC1-C-1_Smoe -----------------SLSYTID------------------------------------
ABC1-C-2_Smoe -----------------SFEYVMG------------------------------------
ADCK2_Mmus ---------ASFL
Y32H12A.7_Cele ----------VLV
YPL109C_Scer ---------GFKE
ADCK2_Hsap ---------VCPP
AdckC_Ddis KNNNNKNNNEKNK
ADCK2_Spur -----------GR
CC1G_01824_Ccin ----QRDWLTPNI
AqueK030_Aque ----------TKI
ABC1-C-1_Smoe --------SIMAP
ABC1-C-2_Smoe --------AIAAP