KDR_Hsap LKLGKPLGRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIG
FLT4_Hsap LHLGRVLGYGAFGKVVEASAFGIHKGSSCDTVAVKMLKEGATASEHRALMSELKILIHIG
FLT1_Hsap LKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIG
CG3277_Dmel IQIGRMLGEGAFGQVHEATAINLRRMRGTTIVAVKQLKPNPKADEVAEYLAEIEMLKGVG
Pvr_Dmel LKLGKQLGAGAFGVVLKGEAKGIRREEPTTTVAVKMVKATADNEVVRALVSELKIMVHLG
KDR_Mmus LKLGKPLGRGAFGQVIEADAFGIDKTATCKTVAVKMLKEGATHSEHRALMSELKILIHIG
FLT4_Mmus LHLGRVLGHGAFGKVVEASAFGINKGSSCDTVAVKMLKEGATASEHRALMSELKILIHIG
FLT1_Mmus LKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIG
VEGFR2_Spur LKLGGVIGKGAFGMVIKAVAVGIDGTENNITVAVKKLKSGATSLEKKALWAELKMLGHIG
VEGFR1_Spur ------------------------------------------------------------
KDR_Hsap HHLNVVNLLGACTKP--GGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKTKGARFRQGKDY
FLT4_Hsap NHLNVVNLLGACTKP--QGPLMVIVEFCKYGNLSNFLRAKRDAFSPCAEKSPEQRGRFRA
FLT1_Hsap HHLNVVNLLGACTKQ--GGPLMVIVEYCKYGNLSNYLKSKRDLFFLNKDAALHMEPKKEK
CG3277_Dmel THHNVVSFLGCCTIK---PPYLMIMEYVNKGNLLSYLRDAFEY-----------------
Pvr_Dmel QHLNVVNLLGAVTKNIAKRELMVIVEYCRFGNIQNFLSTEA-------------------
KDR_Mmus HHLNVVNLLGACTKP--GGPLMVIVEFCKFGNLSTYLRGKRNEFVPYKSKGARFRQGKDY
FLT4_Mmus NHLNVVNLLGACTKP--NGPLMVIVEFCKYGNLSNFLRVKRDTFNPYAEKSPEQRRRFRA
FLT1_Mmus HHLNVVNLLGACTKQ--GGPLMVIVEYCKYGNLSNYLKSKRDLFCLNKDAALHMELKKES
VEGFR2_Spur KHLNVVNFLGACTQ---NGPVLAIVEFCCHGNLLDFLRSKRKYFSETPEGTG--------
VEGFR1_Spur ------------------KDLFVISEFCPFGNLSDYLKTKRKNYVAEPDLLA--------
: * *: **: :*
KDR_Hsap V-GAIPVDLKRRLDSITSSQSSASSGFVEEK----SLSD----VEEEEAPEDLY-KDFLT
FLT4_Hsap MVELARLD---RRRPGSSD-RVLFARFSKTEG---GARR----ASPDQEAEDLW-LSPLT
FLT1_Hsap MEPGLEQGKKPRLDSVTSSESFASSGFQEDK----SLSD----VEEEEDSDGFY-KEPIT
CG3277_Dmel ---------------------------------------------------------ILD
Pvr_Dmel --------------------------------------------------------MTVT
KDR_Mmus V-GELSVDLKRRLDSITSSQSSASSGFVEEK----SLSD----VEEEEASEELY-KDFLT
FLT4_Mmus MVEGAKAD---RRRPGSSD-RALFTRFLMGKG---SARR----APLVQEAEDLW-LSPLT
FLT1_Mmus LEPGLEQGQKPRLDSVSSS-SVTSSSFPEDR----SVSD----VEGDEDYSEIS-KQPLT
VEGFR2_Spur -----SQS---HTG-HSSS-TGASNTFQTSSGSERRMKAVYDQIIPEEVFSPLQ-DDPIN
VEGFR1_Spur IACMGPVD---RSS-RGSS-RGGGDGFMGARGG----ST--LEVGDDDVFEYMEKEQPLT
:
KDR_Hsap LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARD-IYKDPDYV
FLT4_Hsap MEDLVCYSFQVARGMEFLASRKCIHRDLAARNILLSESDVVKICDFGLARD-IYKDPDYV
FLT1_Hsap MEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLARD-IYKNPDYV
CG3277_Dmel NKELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNKTLKISDFGLSRHGIYT-----
Pvr_Dmel TVDLISWAFQVARGMDYLSSKKVLHGDLAARNILLCEDNVVKICDFGLARS-MYRGDNYK
KDR_Mmus LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARD-IYKDPDYV
FLT4_Mmus MEDLVCYSFQVARGMEFLASRKCIHRDLAARNILLSESDIVKICDFGLARD-IYKDPDYV
FLT1_Mmus MEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLARD-IYKNPDYV
VEGFR2_Spur SQDLLCYSFQVARGMEFLASKNVIHRDLAARNVLVTENYTLKICDFGLAKH-LYDDPDYV
VEGFR1_Spur LKDLICYSYQVARGMEFLTSKKCIHRDLAARNVLLAENNIVKICDFGLARD-IYSDPDYV
.* :: *:*.** :* .:: * ******:*: .. :**.****:: :*
KDR_Hsap RKG-DARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRL
FLT4_Hsap RKG-SARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRL
FLT1_Hsap RKG-DTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRL
CG3277_Dmel NTR-TRKLPLRWLSIEAIRENVYSSKSDIWAYGVVLWEIGTLGASPYPTISND-ELIPFL
Pvr_Dmel KSE-NGKLPIKWLALESLSDHVFSTYSDVWSYGIVLWEMFSLAKVPYPGIDPNQELFNKL
KDR_Mmus RKG-DARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRL
FLT4_Mmus RKG-SARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRL
FLT1_Mmus RRG-DTRLPLKWMAPESIFDKVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRL
VEGFR2_Spur ASGKQGRLPIKWMAPESIFDKVFTTYSDVWAYAVFLWEVFSLGGSPYPGIQIDEKFYNKI
VEGFR1_Spur TQT-GGRLPIKWMAPESIFDKVFTIYSDVWSFGVFMWECFALGGSPYPGVVVDEEFYNRL
:**::*:: *:: :.::: **:*::.:.:** :*. *** : : .: :
KDR_Hsap KEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHL
FLT4_Hsap RDGTRMRAPELATPAIRRIMLNCWSGDPKARPAFSELVEIL
FLT1_Hsap REGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKL
CG3277_Dmel MAGNRLERPEICTPQVYTIMLQCWLEEPEERPTFDALYKVL
Pvr_Dmel NDGYRMEKPKFANQELYEIMLECWRKNPESRPLFAELEKRF
KDR_Mmus KEGTRMRAPDYTTPEMYQTMLDCWHEDPNQRPSFSELVEHL
FLT4_Mmus KDGTRMRAPELATPAIRHIMQSCWSGDPKARPAFSDLVEIL
FLT1_Mmus KEGMRMRTPEYATPEIYQIMLDCWHKDPKERPRFAELVEKL
VEGFR2_Spur KNGYRMNAPDYAPPGVYDTMLECWTPEPEARPSFSIL--AV
VEGFR1_Spur KSGYRMYTPDYAPIEIYHVMLDCWHTEPKERPHFSELVHKL
* *: *. : * .** :*. ** * * .