TIF1g_Hsap MAENKGGGEAES------------------GGGGSGSAPVTAGA----------------
TIF1b_Hsap MAASAAAA----------------------------------------------------
TIF1a_Hsap MEVAVEKA----------------------------------------------------
TIF1_Spur MSSSRRSMYSISVLALVFVVGPGVIKLPGAGAGMCGCPPLWTGFNDNCYRFFVSGNLSWF
bon_Dmel MDMDLEQLKN--------------------------------------------------
TIF1a_Mmus MEVAVEKA----------------------------------------------------
TIF1b_Mmus MAASAAAT----------------------------------------------------
TIF1g_Mmus MAENKGGGEAES------------------GGGGSGSAPVTAGA----------------
TIF1D_Hsap MA----------------------------------------------------------
TIF1D_Mmus MA----------------------------------------------------------
*
TIF1g_Hsap ---------AGPAAQEAEP----PLTAVLVEEEEEEGGRA--------------------
TIF1b_Hsap ------------------------------------------------------------
TIF1a_Hsap ------------------------------------------------------------
TIF1_Spur DAELACRTFSTPCGEESSSSSMGHLVSIHSQEEMD-FITAMYDSLRSKRPTIDTRTWIGL
bon_Dmel -------------------D-FLPLIAGIKQEQLD-A-----------------------
TIF1a_Mmus ------------------------------------------------------------
TIF1b_Mmus ------------------------------------------------------------
TIF1g_Mmus ---------AGPTAQEAEP----PLAAVLVEEEEEEGGRA--------------------
TIF1D_Hsap ------------------------------------------------------------
TIF1D_Mmus ------------------------------------------------------------
TIF1g_Hsap ---GAEGGAAGPDDGGVAAASSGS-AQAAS----------------------SPAASVGT
TIF1b_Hsap ------------------SA---A-AASAA----------------------SGSPGPGE
TIF1a_Hsap ------------------VAAAAA-ASAAA----------------------SGGP----
TIF1_Spur HDRTAEQSAEWTDSSDFDYASWAPSQPNDQNGASDCVFFSRNTLYKWNDIPCTPGSRVES
bon_Dmel ----------VP----TDALPQMS-TPNTA----------------------SGAPTTSS
TIF1a_Mmus ------------------AAAAAP-A---------------------------GGPA---
TIF1b_Mmus -----------------AAASAAT-AASAA----------------------SGSPGSGE
TIF1g_Mmus ---GAEGGAAGPDDGGVAAASSSS-APAAS----------------------VPAASVGS
TIF1D_Hsap ------------------------------------------------------------
TIF1D_Mmus ------------------------------------------------------------
TIF1g_Hsap GVAGGAVSTPAP--------------APASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQ
TIF1b_Hsap GSAGGEKRSTAP----SAA------ASASASAAASSPAG-GGAEALELLEHCGVCRERLR
TIF1a_Hsap --------SAAP----SGE------NEAESRQGPDSERG-GEAARLNLLDTCAVCHQNIQ
TIF1_Spur ----------------FVS------DSITSETMEASTSG-QGTSNIHLDLKCKVCEREFS
bon_Dmel LS------SSSL----SLS------NPC-DSAEKRSESN-SSASAKFTLFKCVYCAQLLG
TIF1a_Mmus --------AAAP----SGE------NEAESRQGPDSESG-GEASRLNLLDTCAVCHQNIQ
TIF1b_Mmus GSAGGEKR---P----AAS------SAAAASAAASSPAG-GGGEAQELLEHCGVCRERLR
TIF1g_Mmus AVPGGAASTPAPAAAPAPAPAPAPAPAPAPAPAPGSSSGPPLGPPASLLDTCAVCQQSLQ
TIF1D_Hsap ------------------------------------------------------------
TIF1D_Mmus ------------------------------------------------------------
TIF1g_Hsap SRREAEPKLLPCLHSFCLRCLPEPERQLSVPI----------------------PGGSNG
TIF1b_Hsap P--EREPRLLPCLHSACSACLGPAAPAAA------------------------NSSGDGG
TIF1a_Hsap SR---APKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPP--VPA--PGSPVSGSSP
TIF1_Spur A--DVQPRMLPCLHTVCAQCLANVTNNTAL------------------------ASGQQG
bon_Dmel S--NDRPKLLECLHVACAQCVSTKFSELDRSL----------------------------
TIF1a_Mmus SR---VPKLLPCLHSFCQRCLPAPQRYLMLTAPALGSAETPPPAPAPAPAPGSPAGGPSP
TIF1b_Mmus P--ERDPRLLPCLHSACSACLGPATPAAA------------------------NNSGDGG
TIF1g_Mmus SRREAEPKLLPCLHSFCLRCLPEPERQLSVPI----------------------PGGSNG
TIF1D_Hsap ------------------------------------------------------------
TIF1D_Mmus ------------------------------------------------------------
TIF1g_Hsap DIQQ--VGVIRCPVCRQECRQI-DLVDNYFVKDTSEAPSS---------------SDEKS
TIF1b_Hsap AAGD--GTVVDCPVCKQQCFSK-DIVENYFMRDSGSKAAT---------------DAQDA
TIF1a_Hsap FATQ--VGVIRCPVCSQECAER-HIIDNFFVKDTTEVPSS---------------TVEKS
TIF1_Spur ILAGSGVVIAKCPICKDDIRSLDDIVEDTWTVPMATA--H---------------SMSGG
bon_Dmel ------PPLIHCPVCDNASQQE-FIVDNQFLIEQCTAGDSGDGVGLLGLTGEGQKSSAAA
TIF1a_Mmus FATQ--VGVIRCPVCSQECAER-HIIDNFFVKDTTEVPSS---------------TVEKS
TIF1b_Mmus SAGD--GAMVDCPVCKQQCYSK-DIVENYFMRDSGSKASS---------------DSQDA
TIF1g_Mmus DVQQ--VGVIRCPVCRQECRQI-DLVDNYFVKDTSEAPSS---------------SDEKS
TIF1D_Hsap ------------------------------------------------------------
TIF1D_Mmus ------------------------------------------------------------
TIF1g_Hsap EQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVS-ES-VGASG-
TIF1b_Hsap NQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVKYTKDHTVRSTGP----A-KSRDG-
TIF1a_Hsap NQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEA-VGVTS-
TIF1_Spur EMLCHNCDANAPATNFCVDCPGGLCDPCVLLHGKVRFLRDHVIQPRSEEN----TVSHI-
bon_Dmel SIQCSSCSDGAVATSWCVDCSEYICDSCVQAHQRLKITKDHTIKPKDEANNEQLAGAAGV
TIF1a_Mmus NQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEA-VGVTS-
TIF1b_Mmus NQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVKYTKDHTVRSTGP----A-KTRDG-
TIF1g_Mmus EQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVS-ES-VGTSG-
TIF1D_Hsap -RNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGV-NGGPG-
TIF1D_Mmus -RNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHVPAPGGPLFARAQKGSSGV-NGGSG-
* .*. * *. * :*..* * : . .
TIF1g_Hsap QRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKL
TIF1b_Hsap ERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRL
TIF1a_Hsap QRPVFCPFHKKEQLKLYCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKL
TIF1_Spur VQPPFCTIHPKERLQLYCEKCVRLTCRDCQLVSHKDHSYQFLTEAAASQRLTMRRFIQEL
bon_Dmel DKLHMCQLHPQEKLSLFCETCDKLTCRDCQLSDHRDHKYKFAHEIATESRQALSTLVSEI
TIF1a_Mmus QRPVFCPFHKKEQLKLYCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKL
TIF1b_Mmus ERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRL
TIF1g_Mmus QRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKL
TIF1D_Hsap DFTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQV
TIF1D_Mmus DFALYCPLHTQEVLKLFCETCDVLTCHSCLMVEHKEHRCRHVEEVLQNQRMLLESVTSQV
* .* :* * *:**.* ***:.* : *::* :. : ..: : . .:
TIF1g_Hsap LEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKE
TIF1b_Hsap GDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEG
TIF1a_Hsap MEKTKYIKFTGNQIQNRIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKD
TIF1_Spur QEKRKNAKVMKNNIQIIYKKMKDQESIILGRIDELFNGIRSAIDGQATALKTKIQSSTEN
bon_Dmel NYKRFLLSSATKVIDDRQQLIHDKKKDLIKEITAMAVKITNTVNTRGKQLIMRLNEVCDS
TIF1a_Mmus MEKTKYIKYTGNQIQNRIIEINQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKD
TIF1b_Mmus GDKHATLQKNTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEG
TIF1g_Mmus LEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKE
TIF1D_Hsap AHKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNE
TIF1D_Mmus AHKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNE
* . : : . . : : : :: :. * : .
TIF1g_Hsap RQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDP-
TIF1b_Hsap QQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVDP-
TIF1a_Hsap HRMKLMQQQQEVAGLSKQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDA-
TIF1_Spur KCRTLKQQLIEVGTVDSALSQCYRVIHNIMTSENDVAALQQNRLVKRRVDLVLRTLLTR-
bon_Dmel KLKVLVEKKETLQLLSDNTDHCIDFMQNALEKGSDFAILSSKKSLVRHLQKLKCQRADIP
TIF1a_Mmus HRMKLMQQQQEVAGLSKQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDA-
TIF1b_Mmus QQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVDP-
TIF1g_Mmus RQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDP-
TIF1D_Hsap RKRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNT-
TIF1D_Mmus RKRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKSSVPFLFSKELIVFQMQRLLETRCNT-
: * .: : :. .: . : . .. . * .:. : ::
TIF1g_Hsap VPAANGAIRFHCDP-TFWAKNVVNLGNLVI-ESKPA-------P----------------
TIF1b_Hsap VE-PHGEMKFQWDL-NAWTKSAEAFGKIVA-ERPGT-------N----------------
TIF1a_Hsap SPVTNNTIQFHCDP-SFWAQNIINLGSLVI-EDKESQPQ---MP----------------
TIF1_Spur QPVTELALQFKQTN-VPTRDAFKSIGSIEGMESKVL-FG---PP--------------GQ
bon_Dmel NPEIPVRIQVQLNQVSDLQKVISQLGIIIV-DGKPYP-P---TP----------------
TIF1a_Mmus SPVTNTTIQFHCDP-SFWAQNIINLGSLVI-EDKESQPQ---MP----------------
TIF1b_Mmus VE-PHGEMKFQWDL-NAWTKSAEAFGKIVA-ERPGT-------N----------------
TIF1g_Mmus VPAANGAIRFHCDP-TFWAKNVVNLGNLVI-ESKPA-------P----------------
TIF1D_Hsap DPGSPWSIRFTWEP-NFWTKQLASLGCITT-EGGQMSRAD--APAYGGLQGSSPFYQSHQ
TIF1D_Mmus DPGSPWSIRFTWEP-NFWTKQLASLGCITT-EGGQLTRADAAAASYGSLQGQPSFYQSHQ
::. . :* : :
TIF1g_Hsap ---------------GYTPNV----------------VVGQVPPG---TNHI---SKTPG
TIF1b_Hsap ---------------ST-------------------------------------------
TIF1a_Hsap ---------------KQNPVV----------------EQNSQPPSGLSSNQL---SKFPT
TIF1_Spur QQI------------RQNQGF----------------PHNMQPGLALNRAAL---VQQQA
bon_Dmel ---------------SPNGT-----------------PQPQHPP------------RQPP
TIF1a_Mmus ---------------KQNPVV----------------EQSSQPPGGLPSNQL---SKFPT
TIF1b_Mmus ---------------ST-------------------------------------------
TIF1g_Mmus ---------------GYTPNV----------------VVGQVPPG---TNHI---SKTPG
TIF1D_Hsap SPVAQQEALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPP---SIHPAHSFRQPP
TIF1D_Mmus APMAQQEALSHPSHKFQSPALCSSSVCCSHCSPVSPSLKGQVPPP---SIHPAHSFRQPS
TIF1g_Hsap QINLA-------------------------------------------------------
TIF1b_Hsap ------------------------------------------------------------
TIF1a_Hsap QISLA-------------------------------------------------------
TIF1_Spur QLQAQ-------------------------------------------------------
bon_Dmel SPNMA--------PPLRPGLPPGMPAGLSPNGPPVNFGPQNGP-----------------
TIF1a_Mmus QISLA-------------------------------------------------------
TIF1b_Mmus ------------------------------------------------------------
TIF1g_Mmus QINLA-------------------------------------------------------
TIF1D_Hsap EMVPQQLGSLQCSAL----LPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLT
TIF1D_Mmus EMVPHQLGSLQCSTL----LPREKELACSPHPPKLMQPWLEPQPPAEQESTSQRPGPQLV
TIF1g_Hsap ---------------------------QLRLQHMQQQVYAQKHQQLQQMRMQQPP-----
TIF1b_Hsap -----------------------------------------------------GP-----
TIF1a_Hsap ---------------------------QLRLQHMQQQVMAQRQQ------VQRRP-----
TIF1_Spur ---------------------------QQAQQQAQQQAQQQAHMQ--QRQLQQQQGINHA
bon_Dmel ---------------------------PLYSNAAQQQ--------FNNL-SMSR------
TIF1a_Mmus ---------------------------QLRLQHIQQQVMAQRQQ------VQRRP-----
TIF1b_Mmus -----------------------------------------------------GP-----
TIF1g_Mmus ---------------------------QLRLQHMQQQVYAQKHQQLQQMRLQQPP-----
TIF1D_Hsap SQPVCIVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQ-QQLPPPP-----
TIF1D_Mmus SQPVCIVPPQDVQPGAHAQPTIQTPSIQVQLGHHQKLKLSHFQQQPQ-QQ-PPPP-----
TIF1g_Hsap -----------------------AP---------VPTT-TTTTQQHPRQAAPQ-------
TIF1b_Hsap -----------------------AP---------M--A-PP-RAPGPLSKQGS-------
TIF1a_Hsap -----------------------AP---------VGLP-NP-RMQGPIQQPSI-------
TIF1_Spur LFSQRSIGEQLARVNRPTVCAPTIH---------IPRGLQAQQQQQQQQVRPA-------
bon_Dmel ----------------SF------PGDGSGKVRFGG--MPPVGMQR-HGQPHV-------
TIF1a_Mmus -----------------------AP---------VGLP-NP-RMQGPIQQPSI-------
TIF1b_Mmus -----------------------GP---------M--A-PP-RAPGPLSKQGS-------
TIF1g_Mmus -----------------------AP---------IPTT-TATTQQHPRQAAPQ-------
TIF1D_Hsap -----------------------PP---------LPHP-PP-PLPPPPQQPHPPLPPSQH
TIF1D_Mmus ----------------------------------------P-PPPPPPQHAPPPLPPSQH
.
TIF1g_Hsap ---MLQQQPPRLISVQTMQ----------------------RGNMNCGAFQAHQMRLAQ-
TIF1b_Hsap ---GSSQPMEVQE-----------------------------------------------
TIF1a_Hsap ---SHQQPPPRLINFQN-------------------------------------------
TIF1_Spur ---MQTNILPVLTNPQNTM----------------------GIRPS----TSTQLT----
bon_Dmel ---SSSTHPQ---NMDISL----------------------RGLLNNQAAQSPNAHMAF-
TIF1a_Mmus ---SHQHPPPRLINFQN-------------------------------------------
TIF1b_Mmus ---GSSQPMEVQE-----------------------------------------------
TIF1g_Mmus ---MLQQQPPRLISVQTMQ----------------------RGNMNCGAFQAHQMRLAQ-
TIF1D_Hsap LASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSPQ-HLQQT
TIF1D_Mmus LASSQHESPPGPACSQNVDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSPQ-HLQQT
TIF1g_Hsap NAA-RIPGIPRHSG-PQYSMMQP-HLQRQ---HSNPGHAG----PFP-------------
TIF1b_Hsap -------GYGFGSGDDPYSSAEP-HVSGVKRSRSGEGEVSGLMRKVP-------------
TIF1a_Hsap -----------HSPKPNGPVLPP-HPQQL---RYPPNQNI----PRQA-IK-PNPLQ---
TIF1_Spur ----------HGLPTSMQPVGPP-N------------VTV------TSAMT-FGDLTTAQ
bon_Dmel NGPPSYPGGPQGAPAPAHQPMGP-QM-RP---HFMPGQQG----FSQGGGPGGGPRD---
TIF1a_Mmus -----------HSPKPNGPVLPP-YPQQL---RYSPSQNV----PRQTTIK-PNPLQ---
TIF1b_Mmus -------GYGFGS-DDPYSSAEP-HVSGMKRSRSGEGEVSGLLRKVP-------------
TIF1g_Mmus NAA-RIPGIPRHSA-PQYSMMQP-HLQRQ---HSNPGHAG----PFP-------------
TIF1D_Hsap IVG-QINYIVRQPA-PVQSQSQEETLQAT---DEPPASQG----SKP-------------
TIF1D_Mmus IVG-QINYIVRQPA-PVQSQSQEETLQVT---EEPPAPEG----PKP-------------
TIF1g_Hsap ----------------------------VVSVHN-TTINP--------------------
TIF1b_Hsap ----------------------------RVSLER-LDLDL--------------------
TIF1a_Hsap -MAFLAQQAIKQWQISSGQGTP------STTNS--TSSTP--------------------
TIF1_Spur RKQLMAQ--VKQNQALNARSPPSVSPSAATAVRNTNSASP--------------------
bon_Dmel -ANFMNSNARFQSQYQ------RMAN--------HAQQAA--------------------
TIF1a_Mmus -MAFLAQQAIKQWQISSVQAPP------TTASS--SSSTP--------------------
TIF1b_Mmus ----------------------------RVSLER-LDLDL--------------------
TIF1g_Mmus ----------------------------VVSAHN--PINP--------------------
TIF1D_Hsap ----------------------------ALPLDK-NTAAALPQASGEETPLSVPPVDSTI
TIF1D_Mmus ----------------------------ALPVDK-NTAAPLPQTSGEETPHSVPPVDGTS
TIF1g_Hsap --TSPTTA--------TMANANR-----------GPTSPSVTAIELIPSVT---NPENL-
TIF1b_Hsap --TADSQP--------PVFK----------------------------------------
TIF1a_Hsap --SSPTIT--------SAAGY-D-----------GKA-FGSPMIDLSSPVG---GSYNL-
TIF1_Spur --SSMGAT--------TVRNTNS----------ASPSSMIAPANDTSGPRILSVKSERRP
bon_Dmel --AAAAMA--------GAAGG-G-----------GGQIPSPGALQRPQMMS---NPM---
TIF1a_Mmus --SSPTIT--------SAAGY-D-----------GKA-FSSPMIDLSAPVG---GSYNL-
TIF1b_Mmus --TSDSQP--------PVFK----------------------------------------
TIF1g_Mmus --TSPTTA--------TMANANR-----------GPTSPSVTAIELIPSVT---NPENL-
TIF1D_Hsap QHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVSNL-TAG---APQAV-
TIF1D_Mmus QHSSPNVVRKHATSVSIMGFSNTVEMELSSTRLARTIEPQIHRVSSL-TAA---PTHTI-
::
TIF1g_Hsap ---------------------------------------------------------PSL
TIF1b_Hsap ------------------------------------------------------------
TIF1a_Hsap ---------------------------------------------------------PSL
TIF1_Spur SKSDSERSSCRFENQSSGSTMIGNGLQDTQPSSSGLEMQQGSDKTSPVQSDVQMGGTPER
bon_Dmel ---------------------Q--------------------NV-------------SAM
TIF1a_Mmus ---------------------------------------------------------PSL
TIF1b_Mmus ------------------------------------------------------------
TIF1g_Mmus ---------------------------------------------------------PSL
TIF1D_Hsap ---------------------------------------------------------PSL
TIF1D_Mmus ---------------------------------------------------------PSL
TIF1g_Hsap PD-------------IPPIQLEDAGSSSLD-NLL------------------------SR
TIF1b_Hsap ---------------------VFPGSTTEDYNLI--------------------------
TIF1a_Hsap PD-------------I---DC--SSTIMLD-NIV------------------------RK
TIF1_Spur PDQQMGR--------TPPLTSSATSPDALE-DILGIDLPVQVNASDIIGDIMDEVALETR
bon_Dmel QNSLGFHGSQAGFNTGPPQTSPQLGGGGMH-SLAKWHIPQSAQQSNM-------------
TIF1a_Mmus PD-------------I---DC--SSTIMLD-NIA------------------------RK
TIF1b_Mmus ---------------------VFPGSTTEDYNLI--------------------------
TIF1g_Mmus PD-------------IPPIQLEDAGSSSLD-NLL------------------------SR
TIF1D_Hsap LS-------------APPKMV--SSLTSVQ-NQA------------------------MP
TIF1D_Mmus LS-------------GPPQTV--SSLMSVS-NHA------------------------MP
. .
TIF1g_Hsap Y--ISGSHLPPQPTSTM-N----------------------PSPGPSALSPGSSG---LS
TIF1b_Hsap -------------------V---------------------IERGAAAAATGQPG---TA
TIF1a_Hsap D--TNIDHGQPRPPSNR-TV---------------------QSPNSSVPSPGLAGPVTMT
TIF1_Spur DSGESADNSDPAPTRES-TSE--------------------ETSGSAAEASGDGA-GSVA
bon_Dmel ----CSQQGPLLPFANG-R-Q--------------------TSENFKI---SLKSPNTLK
TIF1a_Mmus D--TGVDHAQPRPPSNR-TV---------------------QSPNSSVPSPGLAGPVTMT
TIF1b_Mmus -------------------V---------------------IERGAAAAAAGQAG---TV
TIF1g_Mmus Y--ISGSHLPPQPTSTM-N----------------------PSPGPSALSPGSSG---LS
TIF1D_Hsap S--LTTSHLQTVPSLVHSTFQSMPNLISDSPQAMASLASDHPQAGPSLMSGHTQAVPS--
TIF1D_Mmus S--LTASHLQPVPNLVRGTFQSTSNLRGDSSQAITGLASNHSQAGPSLMSGHTQAAPS--
. .
TIF1g_Hsap NS---------------------------------HTPVR--PPS---------------
TIF1b_Hsap PA---------------------------------GTPGA--PPL---------------
TIF1a_Hsap SV---------------------------------HPPIR--SPS---------------
TIF1_Spur EASGSGAGSVAGASGSGAGSVAEASGDGTESVAEASGDGA--GPSGSGAGSVSEGSGSGA
bon_Dmel NS---------------------------------TPPSL--------------------
TIF1a_Mmus SV---------------------------------HPPIR--SPS---------------
TIF1b_Mmus PP---------------------------------GAPGA--PPL---------------
TIF1g_Mmus NS---------------------------------HTPVR--PPS---------------
TIF1D_Hsap LA---------------------------------TCPLQSIPPV---------------
TIF1D_Mmus LA---------------------------------TCPLQGMPPV---------------
TIF1g_Hsap ----TSST--GSRGS-CGSSGRTAEKT---------------------------------
TIF1b_Hsap ----AG------------------------------------------------------
TIF1a_Hsap ----ASSV--GSRGS-SGSSSKPAGAD---------------------------------
TIF1_Spur IAPGEGSS--GDPGV-VEASGSGAARA-------------------VGSE----------
bon_Dmel -G--GGGA--GHQGHGNGSSSAQLNAA---------------------------------
TIF1a_Mmus ----ASSV--GSRGS-SGSSSKPAGAD---------------------------------
TIF1b_Mmus ----PG------------------------------------------------------
TIF1g_Mmus ----TSST--GSRGS-CGSSGRTAEKS---------------------------------
TIF1D_Hsap ----SDMQ--PETGS-SSSSGRTSGSLCPRDGADPSLENALCKVRKMESEDSTRFTDLLG
TIF1D_Mmus ----SDVHVEPRSVS-SPGSGPAAESLGTRDGAESSLGNALC---KMESEDCTRFSDSVG
.
TIF1g_Hsap ------------------------------------------------------------
TIF1b_Hsap ------------------------------------------------------------
TIF1a_Hsap ------------------------------------------------------------
TIF1_Spur ------------------------------------------------------------
bon_Dmel ------------------------------------------------------------
TIF1a_Mmus ------------------------------------------------------------
TIF1b_Mmus ------------------------------------------------------------
TIF1g_Mmus ------------------------------------------------------------
TIF1D_Hsap QGPIVPGLDAPKDLAIPSELEEPINLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGAL
TIF1D_Mmus QGPTASSLDGPKDLAIPSELEEPINLSVKKPFLAPVINTSTALQQYRNPKEYENFEQGAL
TIF1g_Hsap ---------------SLS---F-KSDQVKV-------KQEPG----TEDEICSFSG-GVK
TIF1b_Hsap -------------------------------------------------------MAIVK
TIF1a_Hsap --------------STHKVPVV-MLEPIRI-------KQENS----GPPENYDFPVVIVK
TIF1_Spur --------------DVEKHGKE-KLSRIRVFLNEMDDSMHEA----TKESIAAFWKGDVS
bon_Dmel --------------ALGLGPAVSILSNVTS-------TNPKTPSPSTHENTKDFTEPIDK
TIF1a_Mmus --------------STHKVPVV-MLEPIRI-------KQENS----GPPENYDFPVVIVK
TIF1b_Mmus -------------------------------------------------------MAIVK
TIF1g_Mmus ---------------AHS---F-KSDQVKV-------KQEPG----TEEEICSFSG-AVK
TIF1D_Hsap ELDAKENQSIRAFNSEHKIPYV-RLERLKI-------CAASS----GE-----MPVFKL-
TIF1D_Mmus ELDTKENSDIRAISSEPKIPYV-RLERLKI-------CAASS----GE-----MPVFKL-
TIF1g_Hsap -QEKTEDGRRSAC-MLS--------------SP--------ESSLTPPLSTNL-------
TIF1b_Hsap -EEETEAAIGAPPTATE--------------GP--------E---TKPVLMAL-------
TIF1a_Hsap -QESDEESRPQN---AN--------------YP--------RSILTS-----L-------
TIF1_Spur WEERDDQGKPRRQVIVGSLYRMTSKKYSREGWPSKLHIKMMHSGMLKPLIDLMRDHQLFF
bon_Dmel --VRDD-------------------------------------SINDLIATI--------
TIF1a_Mmus -QESDEESRPQN---TN--------------YP--------RSILTS-----L-------
TIF1b_Mmus -EEETEAAIGAPPAAPE--------------GP--------E---TKPVLMPL-------
TIF1g_Mmus -QEKTEDGRRSAC-MLS--------------SP--------ESSLTPPLSTNL-------
TIF1D_Hsap --------KPQK---ND--------------QD--------GSFLL--------------
TIF1D_Mmus --------KPQK---NS--------------QD--------GNFLL--------------
TIF1g_Hsap ------------------------------------------------------------
TIF1b_Hsap ----AEGPG--------------------AEGPR--------------------------
TIF1a_Hsap ------------------------------------------------------------
TIF1_Spur LKCDQECKELYRKLVAIFKNKDVFGAIRLYSKPEIILLLFYSHKHQKFFIVCPQQREQFS
bon_Dmel ------------------------------------------------------------
TIF1a_Mmus ------------------------------------------------------------
TIF1b_Mmus ----TEGPG--------------------AEGPR--------------------------
TIF1g_Mmus ------------------------------------------------------------
TIF1D_Hsap ------------------------------------------------------------
TIF1D_Mmus ------------------------------------------------------------
TIF1g_Hsap ---------HLESELDALASLENHVK-----IEPADMNESCKQSGLS-------------
TIF1b_Hsap ---------LASPSGS-TSSGLEVVA-----PEGT-------------------------
TIF1a_Hsap ---------LLNSSQS-STSEETVLR-----SDAP--DSTGDQPGLHQD-----------
TIF1_Spur IGFVKTMEKYFKVQRK-GASDK--PN-----PESSTVSTADGDPGTSET-----------
bon_Dmel -------------AKL-DSNGVQVLPEGRTKTTSPQVHSSTDL-----------------
TIF1a_Mmus ---------LLNSSQS-SASEETVLR-----SDAP--DSTGDQPGLHQE-----------
TIF1b_Mmus ---------LASPSGS-TSSGLEVVA-----PEVT-------------------------
TIF1g_Mmus ---------HLESELDTLTGLENHVK-----TEPTDISESCKQSGLS-------------
TIF1D_Hsap -----II--ECGT-E-SSSMSIKVSQ--------DRLSEATQAPGLEGRKVTVTSLAGQR
TIF1D_Mmus -----VI--ECGT-E-SSSMSIKVSQ--------NSLPDASQGPGLGGRKVTVTSLTGQQ
:
TIF1g_Hsap -SLVNGKSPI-RSLMHRSA------------------------RIGGDGNNKDDDPNEDW
TIF1b_Hsap -----------------SA------------------------PGGGPG-T--LDDSATI
TIF1a_Hsap -NSSNGKSEW-LDPSQKSP------------------------LHVGE-TRKEDDPNEDW
TIF1_Spur -APTSGEKRP-IDEDVPSTSQAGTSRNGEESIEPIPTWKQGYKLRNGMQCSRSDDPNDDW
bon_Dmel --------------SN--TQ-----------------------EV-NNKNEQKDDPNEDW
TIF1a_Mmus -NSSNGKSEW-SDASQKSP------------------------VHVGE-TRKEDDPNEDW
TIF1b_Mmus -----------------SA------------------------PVSGPG-I--LDDSATI
TIF1g_Mmus -NLVNGKSPI-RNLMHRSA------------------------RIGGDGNSKDDDPNEDW
TIF1D_Hsap PPEVEGTSPEEHRLIPR--------------------------TPGAKKGPPAPIENEDF
TIF1D_Mmus PQEVESTSE-EHRLIPR--------------------------APGAKKNTPAPIENEDF
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TIF1g_Hsap CAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPS--GDWICTFCRDIGKPEVEYDCDNLQ
TIF1b_Hsap CRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPG--EEWSCSLCHVLPDLKEEDGSLSLD
TIF1a_Hsap CAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPS--GEWICTFCRDLSKPEVEYDCDAPS
TIF1_Spur CAVCNNGGNLVCCDRCPRVYHHECHVPLISEVPED-DDFDCTLCFDVVADEEEN-V----
bon_Dmel CAVCLDGGELMCCDKCPKVFHQNCHIPAISSLPDESESWQCLLCVNIKELTKTEGS----
TIF1a_Mmus CAVCQNGGELLCCEKCPKVFHLTCHVPTLTNFPS--GEWICTFCRDLSKPEVDYDCDVPS
TIF1b_Mmus CRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPG--EEWSCSLCHVLPDLKEEDGSLSLD
TIF1g_Mmus CAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPS--GDWICTFCRDIGKPEVEYDCDNMQ
TIF1D_Hsap CAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPG--GEWVCTLCRSLTQPEMEYDCENAC
TIF1D_Mmus CAVCINGGELLCCDRCPKVYHLSCHVPALLSFPG--GEWVCTLCRSLTQPEMEYDCENAR
* ** . *:*: *::* :* **:* : ..* .: * :* :
TIF1g_Hsap HSKK-GKTAQ---GLSPVDQRKCERLLLYLYCH-ELSIEFQEPVPASIPNYYKIIKKPMD
TIF1b_Hsap GADS-TGVV---AKLSPANQRKCERVLLALFCH-EPCRPLHQLATDSTF-SLDQPGGTLD
TIF1a_Hsap HNSE-KKKTEGLVKLTPIDKRKCERLLLFLYCH-EMSLAFQDPVPLTVPDYYKIIKNPMD
TIF1_Spur NNEN-AEKLE---GFTAREFKLCQRLLLEMYCL-EDSQPFLEPVGPEVTGYLEIIPIPMD
bon_Dmel ---E-KSSSG---ELSALELRILQRICLELYCQYEQSLNFREPESPANTSYYEIVSSPMS
TIF1a_Mmus HHSE-KRKSEGLTKLTPIDKRKCERLLLFLYCH-EMSLAFQDPVPLTVPDYYKIIKNPMD
TIF1b_Mmus GADS-TGVV---AKLSPANQRKCERVLLALFCH-EPCRPLHQLATDSTF-SMEQPGGTLD
TIF1g_Mmus HSKK-GKTAQ---GLSPVDQRKCERLLLYLYCH-ELSIEFQEPVPVSIPNYYKIIKKPMD
TIF1D_Hsap YNQPGMRASP---GLSMYDQKKCEKLVLSLCCN-NLSLPFHEPVSPLARHYYQIIKRPMD
TIF1D_Mmus YGHPGVRVLP---GLSMYDQKKCEKLVLSLCCN-SLSLPFHEPVSPLARHYYQIIKRPMD
:: : : ::: * : * . . : : . .:.
TIF1g_Hsap LSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKADSEV
TIF1b_Hsap LTLIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTED-----------------KADV
TIF1a_Hsap LSTIKKRLQEDY-SMYSKPEDFVADFRLIFQNCAEFNEP-----------------DSEV
TIF1_Spur LSTIKSKLSLTSPNKYFSPRQMVEDLRVMFTNCYQYNGE-----------------TSDL
bon_Dmel LDVIRTRLDPSSPNHYKDIAGFVSDVRLIFSNTYLFYQE-----------------DTKT
TIF1a_Mmus LSTIKKRLQEDY-CMYTKPEDFVADFRLIFQNCAEFNEP-----------------DSEV
TIF1b_Mmus LTLIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTED-----------------KADV
TIF1g_Mmus LSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKGDSEV
TIF1D_Hsap LSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYP-----------------DSEV
TIF1D_Mmus LSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYP-----------------DSEV
* :: :*. * .. *. :* : :.
TIF1g_Hsap AQAGKAVALYFEDKLTEIYSD---RTFAPLPEFEQEEDDGE-------------------
TIF1b_Hsap -QSIIGLQRFFETRMNEAFGD---TKFSA-VLVEPPPMSLP-------------------
TIF1a_Hsap ANAGIKLENYFEELLKNLYPE---KRFPK-PEFRNESEDNK-------------------
TIF1_Spur GKIAQHLQRYASRFMKRYLPEYMDSNFVSSANQR--HE----------------------
bon_Dmel YSNAKYLENFFEEQLAKWLPQ---FEGTK-PQGKRNTSNSPALLGVNATGSPSPIENGRK
TIF1a_Mmus ANAGIKLESYFEELLKNLYPE---KRFPK-VEFRHEAEDCK-------------------
TIF1b_Mmus -QSIIGLQRFFETRMNDAFGD---TKFSA-VLVEPPPLNLP-------------------
TIF1g_Mmus AKAGKAVALYFEDKLSEIYSD---RTFTPLPEFEQDEDDGE-------------------
TIF1D_Hsap AEAGRCLEVFFEGWLKEIYPE---KRFAQ-PRQED-SDSEE-------------------
TIF1D_Mmus AEAGRCLEVFFEGWLKEIYPD---KCFAQ-PQQED-SDSED-------------------
. : : . : : .
TIF1g_Hsap ---VT--EDSD-------------EDFIQPRRKRLKSDER-P----------VHIK
TIF1b_Hsap ---GA--GLSS-------------QEL----------SGG-P----------GDGP
TIF1a_Hsap ---FS--DDSD-------------DDFVQPRKKRLKSIEE-R----------QLLK
TIF1_Spur ---------------------------DRPNKRRKQEHPT-P---------VFHIR
bon_Dmel SCGSASLGDSD-------------GACLPAKRARRSA-----------------HE
TIF1a_Mmus ---FS--DDSD-------------DDFVQPRKKRLKSTED-R----------QLLK
TIF1b_Mmus ---SA--GLSS-------------QEL----------S-G-P----------GDGP
TIF1g_Mmus ---VT--EDSD-------------EDFIQPRRKRLKSDER-P----------VHIK
TIF1D_Hsap ---VS--SESGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV
TIF1D_Mmus ---VS--GESGCSTPQGFPWPPYMQEGIQPKRRRRHMENEKTKRVSFRLANSISQV