PRKY_Hsap MEAPGPA------------------------------QA---------------------
PRKX_Hsap MEAPGLA------------------------------QA---------------------
PKACg_Hsap MGNAPAK------------------------------KDT-----------E--------
PKACb_Hsap MAAYREP------------------------------PCN-----------QYTGTT-T-
PKACa_Hsap MGNAAAA------------------------------KKG-----------S--------
Pka-C1_Dmel MGNNATT------------------------------SNK-----------K--------
Pka-C2_Dmel MSQHTSQ------------------------------YVF--------------------
CG12069_Dmel MGPQPEQ------------------------------AQM-----------HF-------
PKA-C3_Dmel MSTATCA------------------------------RFCTPL---SS---G-T------
PRKX_Mmus MEPPAGA------------------------------AA---------------------
PKACb_Mmus MAAHKEL------------------------------SSG-----------QHSGTP-T-
PKACa_Mmus MGNAAAA------------------------------KKG-----------S--------
kin-1_Cele MLKFLKP------------------------------KSS-----------DEG------
F47F2.1_Cele MVILSHH------------------------------KRS-----------PP-L-LMRL
TPK1_Scer MSTEEQN------------------------------GGG-----------QKSL-----
TPK2_Scer MEFVAER------------------------------AQP-----------VGQT-----
TPK3_Scer MYVDPMN------------------------------NNE-----------IRKL-----
DDB0185224_Ddis MSAILNN------------------------------YQY-----------IPNN-SL--
pk4_Ddis QQQQQQQ------------------------------QQQ-----------QQQQ-QQ--
PKA_Ddis MSNSNNN------------------------------SSS-----------G-N------
17649_Tthe MQISEEQ------------------------------FF------------E-QF-----
18333_Tthe MNWEELV------------------------------YKLSYLKIERDNQIE-NL-----
2171_Tthe MEGFKAK------------------------------QVK-----------LTEFDVMNT
26485_Tthe MEKAKKM--------------------------------K--------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin MSFQHHP------------------------------TSL-----------SMPA-----
CC1G_04466_Ccin MIKRMAG------------------------------KLT-----------AHIGGHHNG
CC1G_01089_Ccin MGPVRAN------------------------------KST-----------REAR-----
AqueK013_Aque MALFFPCDVDCEDVFCDCLFKRTEPAHIVRYELQPRPAAT---------TVSHSETQ-P-
AqueK014_Aque MGGHLRK------------------------------DQS-----------KAK-KP-P-
AqueK015_Aque MTDLTHE------------------------------EEE-----------E--------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam MEDIQVE-----------------------------------------------------
GK006_Glam MGQNQSG------------------------------VAG-----------NA-------
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap ------------------------------------------------------------
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap --------------ALQK----------------LE------------------------
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel --------------------A----------------------GSTSKLTTGNGSGNTMT
PRKX_Mmus ------------------------------------------------------------
PKACb_Mmus --------------ALQK----------------LE------------------------
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele ------------------------------------------------------------
F47F2.1_Cele ----F---RICRFF----------------------------------------------
TPK1_Scer ------------------------------------------------------------
TPK2_Scer ------------------------------------------------------------
TPK3_Scer ------------------------------------------------------------
DDB0185224_Ddis ------------------------------------------------------------
pk4_Ddis ------------------------------------------------------------
PKA_Ddis --------------------HNSTTIN----NPKVNVYSNIPNS--TTYTYGSGGGGTLS
17649_Tthe ------------------------------------------------------------
18333_Tthe -------------SLNQKIAENQTKIKNDIFQDSINPFNY--------------------
2171_Tthe ---LGTVCQIVLFN----------------------------------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin ------------------------------------------------------------
CC1G_04466_Ccin KGFLG-------------------------------------------------------
CC1G_01089_Ccin ------------------------------------------------------------
AqueK013_Aque -------------LSVPR------------------------------------------
AqueK014_Aque ------------------------------------------------------------
AqueK015_Aque ------------------------------------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap ------------------------------------------AA---------------A
PRKX_Hsap ------------------------------------------AA---------------A
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap -------------------------------------------------G----------
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel SAYKIPSNN---------ST----------------------TA---------------N
PRKX_Mmus ------------------------------------------TV---------------K
PKACb_Mmus -------------------------------------------------G----------
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele ------------------------------------------------------------
F47F2.1_Cele --------R---------RLM--SS---------------STSS---------------V
TPK1_Scer ------------------------D---------------DRQG---------------E
TPK2_Scer ------------------------I---------------QQQN---------------V
TPK3_Scer ------------------------S---------------ITAK---------------T
DDB0185224_Ddis ------------------------N---------------S-NN---------------S
pk4_Ddis ------------------------QH--------------Q-KT---------------S
PKA_Ddis GN--NTNNNNTNNNNNNNNN----------------------SS---------------G
17649_Tthe ------------------------------------------------------------
18333_Tthe ---IVPFEK---------ES----------------------SS---------------S
2171_Tthe --------L----------NL--SD---------------VQSS-DRYIPFRIGTAFVQK
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin ------------------------EPVRRISITYQQPSCPESQVVV-------------T
CC1G_04466_Ccin --------------------ATGLT---------------PSSP---------------S
CC1G_01089_Ccin ------------------------------------------NH---------------V
AqueK013_Aque -------------------------------------------------P----------
AqueK014_Aque ------------------------------------------------------------
AqueK015_Aque ------------------------------------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap E-----------------------------------------------------------
PRKX_Hsap E-----------------------------------------------------------
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap -------------------------------FASRLF-----------------------
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel D---------------SS---NTETTFTF-------------------------------
PRKX_Mmus D-----------------------------------------------------------
PKACb_Mmus -------------------------------FASRLF-----------------------
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele ------------------------------------------------------------
F47F2.1_Cele E------------SV--E---D--------------------------------------
TPK1_Scer E------------SQ--K---GETS-E---------------------------------
TPK2_Scer N------------T---------YG-QGVLQ------P----------------------
TPK3_Scer E------------TT--P---DNVG-QDIPV------N----------------------
DDB0185224_Ddis N------------------NGNNSTILSLCDNATQL------------------------
pk4_Ddis PSTSFVDYNNINNSNGNNINGTTSTCN---------------------------------
PKA_Ddis D---------------NK---NHSPVTSATD------RLTKMDIEEKWDNKNYEKDEREK
17649_Tthe ------------------------QIKLI--------QL---------------------
18333_Tthe E-----------------------NIDFL--------DA---------------------
2171_Tthe A------------SFYIK---N--------------------------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin E--APITPPLSPKSI--ATKSGAMPVEEMPICSSKPIQI---------------------
CC1G_04466_Ccin E------------AM-YP---DTTTLPTIPM------AV---------------------
CC1G_01089_Ccin E-----------------------------------------------------------
AqueK013_Aque -------------------------------TPSRQI-----------------------
AqueK014_Aque ------------------------------------------------------------
AqueK015_Aque E------------RM--Q---H--------------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap ------------------------------------------------------------
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap -------HRH-----------------------------------------------SKG
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel -KLGRSNGRSSSNV---------------------ASS----------------------
PRKX_Mmus ------------------------------------------------------------
PKACb_Mmus -------HRH-----------------------------------------------SRG
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele ------------------------------------------------------------
F47F2.1_Cele ------------------------------------------------------------
TPK1_Scer --------------------------------------------------------R---
TPK2_Scer --------------------------------------------------------H---
TPK3_Scer --------------------------------------------------------A---
DDB0185224_Ddis --------------------------------------------------------M---
pk4_Ddis ------------------------------------------------------------
PKA_Ddis SP---LFHILASNLNSFGNFKVPSTFSLTPPEPNKQQQPQQQPQQQQPQQQQPQQQQ---
17649_Tthe -----------------------------------AKI----------------KQR---
18333_Tthe -----------------------------------QQN----------------EQD---
2171_Tthe ------------------------------------------------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin --------------------------------------------------------HSEQ
CC1G_04466_Ccin -----------------------------------SSL----------------EHR---
CC1G_01089_Ccin ------------------------------------------------------------
AqueK013_Aque -------QQD-----------------------------------------------DNN
AqueK014_Aque ------------------------------------------------------------
AqueK015_Aque ------------------------------------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap -----------------------------S------------------------------
PRKX_Hsap -----------------------------S------------------------------
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap T-----------AHDQ-------------K-------TAL----E---------------
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel -----------------------------E------------------------------
PRKX_Mmus -----------------------------P------------------------------
PKACb_Mmus T-----------AQEH-------------R-------AAL----E---------------
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele -------------------------------------SSK----D---------------
F47F2.1_Cele --------------E--------------S-------CSN----E--CSA----------
TPK1_Scer --------------E--------------T-------TAT----E--SGN----------
TPK2_Scer --------------H---------------------------------------------
TPK3_Scer --------------H--------------S-------VHE----E--C-S----------
DDB0185224_Ddis --------------DIIMREFNEPIFDYNQ-------NSS----EINK------------
pk4_Ddis -----------------------------S-------TSS----S-KS------------
PKA_Ddis -----------------------------P-------------------QQQQ-------
17649_Tthe -----------------------------E-------------------EQQ--------
18333_Tthe -----------------------------S-------------------DEDDYQYDEDE
2171_Tthe --------------K--------------E-------IYS--------AS----------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin --------------E--------------A-------MDV----E--SAP----------
CC1G_04466_Ccin --------------D--------------S-------IST----E--RTS----------
CC1G_01089_Ccin -----------------------------AGPTQRSPP----------------------
AqueK013_Aque NNNDNNEDCSRTSHES-------------R-------QNIDRFDE---------------
AqueK014_Aque -------------LN--------------S-------SAM----G---------------
AqueK015_Aque --------------Q--------------T-------VLP-------AQT----------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap ------------------------------------N-SR---------E----------
PRKX_Hsap ------------------------------------D-SR---------K----------
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap -N------------------DS--LHFSE-------------------------------
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel ------------------------------------S-SD---------P----------
PRKX_Mmus ------------------------------------D-HD---------P----------
PKACb_Mmus -D------------------DG--LRASE-------------------------------
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele ------------------------------------------------------------
F47F2.1_Cele --------------------------------------SF---------T----------
TPK1_Scer ------------------------------------E-SK---------S----------
TPK2_Scer -------------------------------------------------D----------
TPK3_Scer ------------------------------------S-NT---------P----------
DDB0185224_Ddis ------------------------------------SLVK---------TIKS-------
pk4_Ddis ------------------------------------NSKE---------IYNENNNNNNN
PKA_Ddis ---QQQPQQQQQPQ--------QQLQQNNQQQQQQLQ-QQ---------Q----------
17649_Tthe ---NRNGD------------------------I--QQ-SE---------P----------
18333_Tthe EDEDDNGEENEQYFNQIKMNENAILN-NNQNAQ--NQ-KMNKIQFQCFED----------
2171_Tthe --------------------------------------SY---------L----------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin ------------------------------------V-HQ---------H----------
CC1G_04466_Ccin ---------------------------------------T--------------------
CC1G_01089_Ccin --------------------------------------QA---------PY---------
AqueK013_Aque -D----------LSLALYLSSQ--VETNS-------------------------------
AqueK014_Aque ------------------------------------------------------------
AqueK015_Aque --------------------------------------ST---------T----------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap ------------------------------------------------------------
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap ------------------------------------------------------------
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel ------------------------------------------------------------
PRKX_Mmus ------------------------------------------------------------
PKACb_Mmus ------------------------------------------------------------
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele ------------------------------------------------------------
F47F2.1_Cele --------------------------FD--------------------------------
TPK1_Scer --------------------------VE--------------------------------
TPK2_Scer --------------------------LQ--------------------------------
TPK3_Scer --------------------------VE--------------------------------
DDB0185224_Ddis -------------------------LLETLTKNLNNINNNIN-----------------N
pk4_Ddis NNNNSFTNVHNNNNNNNNNRKRRNSHISYDTPDSNNIDNNIESNDTESGFRKNSKKSTDN
PKA_Ddis ------------------------------------------------------------
17649_Tthe ------------------------------------------------------------
18333_Tthe ------------------------------------------------------------
2171_Tthe --------------------------ID--------------------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin --------------------------PN--------------------------------
CC1G_04466_Ccin ------------------------------------------------------------
CC1G_01089_Ccin ------------------------------------------------------------
AqueK013_Aque ------------------------------------------------------------
AqueK014_Aque ------------------------------------------------------------
AqueK015_Aque --------------------------TD--------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap ------------------------------------------------------------
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap -------------H----------------------------------------------
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel ------------------------------------------------------------
PRKX_Mmus ------------------------------------------------------------
PKACb_Mmus -------------H----------------------------------------------
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele ------------------------------------------------------------
F47F2.1_Cele ---------TN---N---------------------------------------------
TPK1_Scer ---------KE-GGE---------------------------------------------
TPK2_Scer ---------QR---Q---------------------------------------------
TPK3_Scer ---------IN-GRN---------------------------------------------
DDB0185224_Ddis NISNNNNNNNN----NNNNN-NNNNNNNN---------------NINNNNNFNTPQIIIN
pk4_Ddis ----NNNNNNNNNNNNNNNNNNNNNNNNNNSCNINGNINNGNSNNINNNNCSNID-----
PKA_Ddis ------------------------------------------------------------
17649_Tthe ------------------------------------------------------------
18333_Tthe ------------------------------------------------------------
2171_Tthe ---------SL---Y---------------------------------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin ---------TMPGEQ---------------------------------------------
CC1G_04466_Ccin --------------S---------------------------------------------
CC1G_01089_Ccin ------------------------------------------------------------
AqueK013_Aque -------------N----------------------------------------------
AqueK014_Aque -------------N----------------------------------------------
AqueK015_Aque ---------SV---A---------------------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap ------------------------------------------------------------
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap ------------------------------------------------------------
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel ------------------------------------------------------------
PRKX_Mmus ------------------------------------------------------------
PKACb_Mmus ------------------------------------------------------------
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele ------------------------------------------------------------
F47F2.1_Cele ------------------------------------------------------------
TPK1_Scer ------------------------------------------------------------
TPK2_Scer ------------------------------------------------------------
TPK3_Scer ------------------------------------------------------------
DDB0185224_Ddis DNYKLYTPPPAPMLKGLSCEVPFETMEYMQPLDLSNNNISLNNSCNMI------------
pk4_Ddis --------------------------------------------STLADVSKHQYTNQHQ
PKA_Ddis ------------------------------------------------------------
17649_Tthe ------------------------------------------------------------
18333_Tthe ------------------------------------------------------------
2171_Tthe ------------------------------------------------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin ------------------------------------------------------------
CC1G_04466_Ccin ------------------------------------------------------------
CC1G_01089_Ccin ------------------------------------------------------------
AqueK013_Aque ------------------------------------------------------------
AqueK014_Aque ------------------------------------------------------------
AqueK015_Aque ------------------------------------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap -----------------------VT---E-D-----AA---------DW-----------
PRKX_Hsap -----------------------VA---E-E-----TP---------DG-----------
PKACg_Hsap -----------------------QE---E-S-----VN---------E--F---------
PKACb_Hsap ----------------T-AL---WD---R-S-----MK---------E--F---------
PKACa_Hsap -----------------------EQ---E-S-----VK---------E--F---------
Pka-C1_Dmel ------------------VD---AA---E-T-----VK---------E--F---------
Pka-C2_Dmel -------------------N---SK---E-D-----YN---------V--I---------
CG12069_Dmel -------------------S---PK---V-D-----YI---------L--I---------
PKA-C3_Dmel -----------------------LE---S-D-----YS---------EEDP---------
PRKX_Mmus -----------------------VK---T-K-----VS----------------------
PKACb_Mmus ----------------T-AS---WD---K-S-----MK---------E--F---------
PKACa_Mmus -----------------------EQ---E-S-----VK---------E--F---------
kin-1_Cele ------------------NK---NS---A-S-----LK---------E--F---------
F47F2.1_Cele -----------------NSR---GN---N-Q-----VN---------E--L---------
TPK1_Scer -----------T-----QEK---PK---QPH-----VT---------YY-N---------
TPK2_Scer -----------------QQQ---QQ---R-Q-----HQ---------Q------------
TPK3_Scer -----------------SGK---LK---E-E-----AS---------A--G---------
DDB0185224_Ddis NNDNNNNNNNNNNNNNNNNN---NN---N-Q-----QQ---------Q--FY--------
pk4_Ddis QQQNIQQQQQQQQQKNQQQQ---QQ---Q-Q-----QQ---------Q--QQNNQQQQQN
PKA_Ddis -----------------------LQ---Q-Q-----LQ---------QQQQ---------
17649_Tthe -----------------------FVE--D-D-----LI---------SE-F---------
18333_Tthe -----------------------FDDKEN-DYCNDLNK---------NE-F---------
2171_Tthe -----------KARKNSASQHSYIH---N-K-----IK---------K--N---------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin -----------------QAQ---SQ---D-Q-----SN---------E--S---------
CC1G_04466_Ccin -----------------MGD---ES---V-A-----GG---------R--F---------
CC1G_01089_Ccin ------------------EE---KK---E-D-----GYVLVAAGKLGR--V---------
AqueK013_Aque ------------------QN---EQ---S-N-----SN---------S--F---------
AqueK014_Aque ----------------A-PG---KP---D-V-----VQ---------A--F---------
AqueK015_Aque -----------------ASE---LA---R-H-----LG---------Q--V---------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam -------------------G---F----K-D-----AD----------------------
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap ------------------------------------------------------------
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap ------------------------------------------------------------
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel ------------------------------------------------------------
PRKX_Mmus ------------------------------------------------------------
PKACb_Mmus ------------------------------------------------------------
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele ------------------------------------------------------------
F47F2.1_Cele ------------------------------------------------------------
TPK1_Scer ------------------------------------------------------------
TPK2_Scer ------------------------------------------------------------
TPK3_Scer ------------------------------------------------------------
DDB0185224_Ddis ------------------------------------NAPSSNSTPSHSSPSSPT------
pk4_Ddis NQQQQQNNQQQQQHQQQNSQQQQNNQHQQQLQQQQYQQKHYNNNNNNNNNNQPQTSNQNI
PKA_Ddis ------------------------------------------------------------
17649_Tthe ------------------------------------------------------------
18333_Tthe ------------------------------------------------------------
2171_Tthe ------------------------------------------------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin ------------------------------------------------------------
CC1G_04466_Ccin ------------------------------------------------------------
CC1G_01089_Ccin ------------------------------------------------------------
AqueK013_Aque ------------------------------------------------------------
AqueK014_Aque ------------------------------------------------------------
AqueK015_Aque ------------------------------------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap ------------------------------------------------------------
PKACg_Hsap -----------------------------------L--AKA-------------------
PKACb_Hsap -----------------------------------L--AKA-------------------
PKACa_Hsap -----------------------------------L--AKA-------------------
Pka-C1_Dmel -----------------------------------L--EQA-------------------
Pka-C2_Dmel -----------------------------------L--DNM-------------------
CG12069_Dmel -----------------------------------L--DKL-------------------
PKA-C3_Dmel -----------------------------------EQEQQRP------------------
PRKX_Mmus ------------------------------------------------------------
PKACb_Mmus -----------------------------------L--AKA-------------------
PKACa_Mmus -----------------------------------L--AKA-------------------
kin-1_Cele -----------------------------------L--DKA-------------------
F47F2.1_Cele -----------------------------------A--EET-------------------
TPK1_Scer -----------------------------------E--EQY-------------------
TPK2_Scer --------------------------------------LLT-------------------
TPK3_Scer -----------------------------------I--CLV-------------------
DDB0185224_Ddis ----------------TSSIPFH----------PNF--TLS-------------------
pk4_Ddis QHSQGLNYNQNQNQNQNQEAPIVVNSLILRSIGMMT--SKI-------------------
PKA_Ddis -----------------------------------QQQQQQQQQQQKQQKQQQQQQQHLH
17649_Tthe -----------------------------------NHLIEI-------------------
18333_Tthe -----------------------------------NKNFEK-------------------
2171_Tthe -----------------------------------E--AEN-------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin -----------------------------------Q--NRP-------------------
CC1G_04466_Ccin -----------------------------------G--IEA-------------------
CC1G_01089_Ccin -----------------------------------YKSAYD-------------------
AqueK013_Aque -----------------------------------V--SLI-------------------
AqueK014_Aque -----------------------------------L--VEA-------------------
AqueK015_Aque -----------------------------------S--LES-------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap ------------------------------------------------------------
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap ------------------------------------------------------------
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel ------DPATNSRSSSTATTTTTSSADHDNDVDEEDEEDDENEGEGNGRDADDATHDSSE
PRKX_Mmus ------------------------------------------------------------
PKACb_Mmus ------------------------------------------------------------
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele ------------------------------------------------------------
F47F2.1_Cele ------------------------------------------------------------
TPK1_Scer ------------------------------------------------------------
TPK2_Scer ------------------------------------------------------------
TPK3_Scer ------------------------------------------------------------
DDB0185224_Ddis ------------------------------------------------------------
pk4_Ddis ------------------------------------------------------------
PKA_Ddis QDGIVNTPSTTQTSTTTTTTTTT-TNPHTSGLSLQH---------------------AHS
17649_Tthe ------------------------------------------------------------
18333_Tthe --NSDYYPTQK-------------------------------------------------
2171_Tthe ------------------------------------------------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin ------------------------------------------------------------
CC1G_04466_Ccin ------------------------------------------------------------
CC1G_01089_Ccin ------------------------------------------------------------
AqueK013_Aque ------------------------------------------------------------
AqueK014_Aque ------------------------------------------------------------
AqueK015_Aque ------------------------------------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap ----------------------------------------A---------PA---LC---
PRKX_Hsap ----------------------------------------A---------PA---LC---
PKACg_Hsap ----------------------------------------R---------GD---FL---
PKACb_Hsap ----------------------------------------K---------ED---FL---
PKACa_Hsap ----------------------------------------K---------ED---FL---
Pka-C1_Dmel ----------------------------------------K---------EE---FE---
Pka-C2_Dmel ----------------------------------------S---------RE---FE---
CG12069_Dmel ----------------------------------------R---------ED---FN---
PKA-C3_Dmel S--------------------IE-----EDDGNETDDEEDD---------DE---SE---
PRKX_Mmus ----------------------------------------A---------PA---AD---
PKACb_Mmus ----------------------------------------K---------ED---FL---
PKACa_Mmus ----------------------------------------K---------ED---FL---
kin-1_Cele ----------------------------------------R---------ED---FK---
F47F2.1_Cele ------------------------------------------------------------
TPK1_Scer --------------------------------------------------------K---
TPK2_Scer --------------------------------------------------------S---
TPK3_Scer --------------------------------------------------------K---
DDB0185224_Ddis ----------------------------------------Q---------DN---FN---
pk4_Ddis ----------------------------------------S---------KD---FE---
PKA_Ddis SYTPSNVLHSPTHFQSSLPTRLDTNPITTPIRQQQQSQQQLQQQQ-----LQ---QI---
17649_Tthe -------------------------P-----------------------------LN---
18333_Tthe ------------------------NPLEQIE---FQAKQNIQYAYTQKQKNN---QN---
2171_Tthe ------------------------------------------------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin ----------------------------------------Q---------RC---L----
CC1G_04466_Ccin --------------------------------------------------------P---
CC1G_01089_Ccin ----------------------------------------E---------ER---FEKPV
AqueK013_Aque ----------------------------------------E---------EDEENWD---
AqueK014_Aque ----------------------------------------K---------TE---FQ---
AqueK015_Aque ----------------------------------------S---------PI---LS---
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap ------------------------------------------------------------
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap ------------------------------------------------------------
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel ------------------------------------------------------------
PRKX_Mmus ------------------------------------------------------------
PKACb_Mmus ------------------------------------------------------------
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele ------------------------------------------------------------
F47F2.1_Cele ------------------------------------------------------------
TPK1_Scer ------------------------------------------------------------
TPK2_Scer ------------------------------------------------------------
TPK3_Scer ------------------------------------------------------------
DDB0185224_Ddis --Q---------------------------------------------------------
pk4_Ddis --ELTTFMKSSCPMLLRFSGVENSYHILEKLNNIITQSLEGLPKTPQCSQPPFNQLIPLS
PKA_Ddis ------------------------------------------------------------
17649_Tthe ------------------------------------------------------------
18333_Tthe ------------------------------------------------------------
2171_Tthe ------------------------------------------------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin ------------------------------------------------------------
CC1G_04466_Ccin ------------------------------------------------------------
CC1G_01089_Ccin PDP---------------------------------------------------------
AqueK013_Aque ------------------------------------------------------------
AqueK014_Aque ------------------------------------------------------------
AqueK015_Aque ------------------------------------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap ------------------------------------------------------------
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap ------------------------------------------------------------
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel ------------------------------------------------------------
PRKX_Mmus ------------------------------------------------------------
PKACb_Mmus ------------------------------------------------------------
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele ------------------------------------------------------------
F47F2.1_Cele ------------------------------------------------------------
TPK1_Scer ------------------------------------------------------------
TPK2_Scer ------------------------------------------------------------
TPK3_Scer ------------------------------------------------------------
DDB0185224_Ddis ------------------------------------------------------------
pk4_Ddis NTTTLTPNNYNNNNNNSNNNNNSNNNNNNNSNNNNSNNNNSNNSNNNNNNSNNNNSNNNN
PKA_Ddis ------------------------------------------------------------
17649_Tthe ------------------------------------------------------------
18333_Tthe ------------------------------------------------------------
2171_Tthe ------------------------------------------------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin ------------------------------------------------------------
CC1G_04466_Ccin ------------------------------------------------------------
CC1G_01089_Ccin ------------------------------------------------------------
AqueK013_Aque ------------------------------------------------------------
AqueK014_Aque ------------------------------------------------------------
AqueK015_Aque ------------------------------------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap ------------------------------------------------------------
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap ------------------------------------------------------------
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel ------------------------------------------------------------
PRKX_Mmus ------------------------------------------------------------
PKACb_Mmus ------------------------------------------------------------
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele ------------------------------------------------------------
F47F2.1_Cele ------------------------------------------------------------
TPK1_Scer ------------------------------------------------------------
TPK2_Scer ------------------------------------------------------------
TPK3_Scer ------------------------------------------------------------
DDB0185224_Ddis -------------------------------------------QLQNNNNSNNNSNNNNN
pk4_Ddis SNNNNSNNNNNNSNNNNSNNNNSSNNNNNYSGFNDQQQQQQQQQQQQQQQQQQQ------
PKA_Ddis ------------------------------------------------------------
17649_Tthe ------------------------------------------------------------
18333_Tthe ------------------------------------------------------------
2171_Tthe ------------------------------------------------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin ------------------------------------------------------------
CC1G_04466_Ccin ------------------------------------------------------------
CC1G_01089_Ccin ------------------------------------------------------------
AqueK013_Aque ------------------------------------------------------------
AqueK014_Aque ------------------------------------------------------------
AqueK015_Aque ------------------------------------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap ------P---------SPE-----------------------------------------
PRKX_Hsap ------P---------SPE-----------------------------------------
PKACg_Hsap ----------------YR------------------------------------------
PKACb_Hsap ----------------KK------------------------------------------
PKACa_Hsap ----------------KK------------------------------------------
Pka-C1_Dmel ----------------DK------------------------------------------
Pka-C2_Dmel ----------------ERW-----------------------------------------
CG12069_Dmel ----------------KKF-----------------------------------------
PKA-C3_Dmel ------E---------SSS-----------------------------------------
PRKX_Mmus ------P---------KPR-----------------------------------------
PKACb_Mmus ----------------RK------------------------------------------
PKACa_Mmus ----------------KK------------------------------------------
kin-1_Cele ----------------QR------------------------------------------
F47F2.1_Cele ------H---------MKL-----------------------------------------
TPK1_Scer ------Q---------FIA-----------------------------------------
TPK2_Scer ------Q---------LPQ-----------------------------------------
TPK3_Scer ------K---------PML-----------------------------------------
DDB0185224_Ddis NNIINNNFLQNSQQTNQSLQF---S----------------------------TTQPNL-
pk4_Ddis --------QQQQQQQHQQQKHQQTQHSQQHQQQYQQHIQQNNQYQQNQNITQSSQIPQFK
PKA_Ddis ------P---------PPT-----------------------------------------
17649_Tthe ----------------QQG-----------------------------------------
18333_Tthe ------Q---------AQI-----------------------------------------
2171_Tthe ------R---------NQI-----------------------------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin ----------------EDQ-----------------------------------------
CC1G_04466_Ccin ------R---------FSA-----------------------------------------
CC1G_01089_Ccin ------E---------LVQ-----------------------------------------
AqueK013_Aque ----------------DF------------------------------------------
AqueK014_Aque ----------------RK------------------------------------------
AqueK015_Aque ------G---------AGS-----------------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap ------------------------------------------------------------
PKACg_Hsap ------------------------------------------------------------
PKACb_Hsap ------------------------------------------------------------
PKACa_Hsap ------------------------------------------------------------
Pka-C1_Dmel ------------------------------------------------------------
Pka-C2_Dmel ------------------------------------------------------------
CG12069_Dmel ------------------------------------------------------------
PKA-C3_Dmel ------------------------------------------------------------
PRKX_Mmus ------------------------------------------------------------
PKACb_Mmus ------------------------------------------------------------
PKACa_Mmus ------------------------------------------------------------
kin-1_Cele ------------------------------------------------------------
F47F2.1_Cele ------------------------------------------------------------
TPK1_Scer ------------------------------------------------------------
TPK2_Scer ------------------------------------------------------------
TPK3_Scer ------------------------------------------------------------
DDB0185224_Ddis ------------------------------------------------NNFYDIPKQPII
pk4_Ddis SNNIQSLIHNNQQHYTQNNLVNNNNNTNNNNNNNNYNNKTYYQPSVHENQYMASAIAPIH
PKA_Ddis ------------------------------------------------------------
17649_Tthe ------------------------------------------------------------
18333_Tthe ------------------------------------------------------------
2171_Tthe ------------------------------------------------------------
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin ------------------------------------------------------------
CC1G_04466_Ccin ------------------------------------------------------------
CC1G_01089_Ccin ------------------------------------------------------------
AqueK013_Aque ------------------------------------------------------------
AqueK014_Aque ------------------------------------------------------------
AqueK015_Aque ------------------------------------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ------------------------------------------------------------
GK006_Glam ------------------------------------------------------------
PRKY_Hsap --------------------A-------------------------R-S-P-EAP-----
PRKX_Hsap --------------------A-------------------------L-S-P-EPP-----
PKACg_Hsap --------------------W-------------------------G-N-P-AQN-----
PKACb_Hsap --------------------W-------------------------E-N-P-TQN-----
PKACa_Hsap --------------------W-------------------------E-S-P-AQN-----
Pka-C1_Dmel --------------------W-------------------------R-R-N-PTN-----
Pka-C2_Dmel --------------------N-------------------------H-Q-T-QSP-----
CG12069_Dmel --------------------A-------------------------T-N-T-PSP-----
PKA-C3_Dmel --------------------V-------------------------QTA-K-GVR-----
PRKX_Mmus --------------------T---------------------------S-S-QKA-----
PKACb_Mmus --------------------W-------------------------E-N-P-PPS-----
PKACa_Mmus --------------------W-------------------------E-T-P-SQN-----
kin-1_Cele --------------------W-------------------------E-N-P-AQN-----
F47F2.1_Cele --------------------S-------------------------I-T-P-TRE-----
TPK1_Scer --------------------Q-------------------------A-R-V-TVG-----
TPK2_Scer --------------------K-------------------------S-L-V-SKG-----
TPK3_Scer --------------------Q-------------------------Y-R-D-TSG-----
DDB0185224_Ddis CSSPIVNIPPPFYLDGSIDPV-------------------------E-N-I-DWK-----
pk4_Ddis ---NHQSSPNPFYQQKLTIPQQTNNQSTRISAQFIIQNINNQQIQGT-Y-I-NFN-----
PKA_Ddis ----------------VNSFF-------------------------LPP-P-VNA-----
17649_Tthe --------------------K-------------------------I-Q-T-KSD-----
18333_Tthe --------------------I-------------------------K-K-E-QND-----
2171_Tthe --------------------K-------------------------N-F-K-AKAACIKI
26485_Tthe ------------------------------------------------------------
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin --------------------R-------------------------V-R-L-QGS-----
CC1G_04466_Ccin --------------------R-------------------------P-Q-R-PKG-----
CC1G_01089_Ccin --------------------P-------------------------V-S-K-RPP-----
AqueK013_Aque --------------------S-------------------------E-HLPTESD-----
AqueK014_Aque --------------------W-------------------------E-S-P-PAQ-----
AqueK015_Aque --------------------R-------------------------E-A-R-YTR-----
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam ----------------------------------------------------AYP-----
GK006_Glam ----------------------------------------------A-Y-I-DPP-----
PRKY_Hsap ----------------AYRLQDCDALVTMGTGTFGRV--HLVKEKT-------AKHFFAL
PRKX_Hsap ----------------VYSLQDFDTLATVGTGTFGRV--HLVKEKT-------AKHFFAL
PKACg_Hsap ----------------TASSDQFERLRTLGMGSFGRV--MLVRHQE-------TGGHYAM
PKACb_Hsap ----------------NAGLEDFERKKTLGTGSFGRV--MLVKHKA-------TEQYYAM
PKACa_Hsap ----------------TAHLDQFERIKTLGTGSFGRV--MLVKHKE-------TGNHYAM
Pka-C1_Dmel ----------------TAALDDFERIKTLGTGSFGRV--MIVQHKP-------TKDYYAM
Pka-C2_Dmel ----------------YTNLENYITRAVLGNGSFGTV--MLVREKSG-------KNYYAA
CG12069_Dmel ----------------STGLDDYEIKATLGSGSFGKV--QLVRERES-------GVYYAS
PKA-C3_Dmel ----------------KYHLDDYQIIKTVGTGTFGRV--CLCRDRI-------SEKYCAM
PRKX_Mmus ----------------GHSLQDWDTIATVGTGTFGRV--NLVKEKT-------GRQYCAL
PKACb_Mmus ----------------NAGLEDFERKKTLGTGSFGRV--MLVKHKA-------TEQYYAM
PKACa_Mmus ----------------TAQLDQFDRIKTLGTGSFGRV--MLVKHKE-------SGNHYAM
kin-1_Cele ----------------TACLDDFDRIKTLGTGSFGRV--MLVKHKQ-------SGNYYAM
F47F2.1_Cele ----------------SFSLSQLERIITIGKGTFGRV--ELARDKI-------TGAHYAL
TPK1_Scer ----------------SIVYKNFQILRTLGTGSFGRV--HLIRSRH-------NGRYYAM
TPK2_Scer ----------------KYTLHDFQIMRTLGTGSFGRV--HLVRSVH-------NGRYYAI
TPK3_Scer ----------------KYSLSDFQILRTLGTGSFGRV--HLIRSNH-------NGRFYAL
DDB0185224_Ddis ----------------RTKISDFNFYGSLGSGSFGTA--KLCRHRG-------SGLFFCS
pk4_Ddis ----------------SCKLSDFKLFDLLGSGSFAKV--RLCQHIP-------SERLFCM
PKA_Ddis ----------------RERLKEFKQIRVIGTGTFGKV--YLIQNTK-------DGCYYAM
17649_Tthe ----------------TMKISDFEIFATLGTGTFGRV--RQVKLKGDT-----NKEIFAL
18333_Tthe ----------------TLNLNQFNIKTTLGTGSFGRV--KLAKLKGN------EKDVFAL
2171_Tthe QSLITLLIKNNFSTFLLFCESSKKQQQSINRCSFGRV--RLAKQKS-------TGEYVAL
26485_Tthe -------------------LSDYEIFQTLGTGSFGRV--KLAKKKN-------TTQYVAL
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin ----------------GLKLSDFEVRGTLGTGTFGKV--LLVRHKTARDR-HGAQSHFAM
CC1G_04466_Ccin ----------------TYRLSDFSIQRTLGTGSFGRV--HLVRSKH-------NGRFYAI
CC1G_01089_Ccin ----------------PLGLQDLEIIKALGDGAEGRV--YLVRTTRSSHPLDRPGTLYAV
AqueK013_Aque ----------------SIPLIDFSDDGPLNEGANPPNYWDIISHSA-----NLADESHAP
AqueK014_Aque ----------------TGKLDDFDRIKTLGTGSFGRV--MLVQHKK-------TSKYYAM
AqueK015_Aque ----------------KFSLRELEIQQTIGTGTFGRV--VLTREIS-------SRQYYAL
PKA-1_Smoe -------------------IEEFELGRVLGTGSFGRV--QVAHHKA-------NKQVCAV
PKA-2_Smoe -------------------IEEFELGRVLGTGSFGRV--QVAHHKA-------NKQVCAV
GK005_Glam ----------------ELSYKDLRHIKNIGSGSFGRV--TLAQHID-------TGKYYAV
GK006_Glam ----------------PTSPDEFTFMKVLGKGSFGTV--CLAKHKA-------NNKIYAL
PRKY_Hsap KVM-------------------SIPDV-IRRKQ----EQH---VHNEKSVLKEVS-HPFL
PRKX_Hsap KVM-------------------SIPDV-IRLKQ----EQH---VHNEKSVLKEVS-HPFL
PKACg_Hsap KIL-------------------NKQKV-VKMKQ----VEH---ILNEKRILQAID-FPFL
PKACb_Hsap KIL-------------------DKQKV-VKLKQ----IEH---TLNEKRILQAVN-FPFL
PKACa_Hsap KIL-------------------DKQKV-VKLKQ----IEH---TLNEKRILQAVN-FPFL
Pka-C1_Dmel KIL-------------------DKQKV-VKLKQ----VEH---TLNEKRILQAIQ-FPFL
Pka-C2_Dmel KMM-------------------SKEDL-VRLKQ----VAH---VHNEKHVLNAAR-FPFL
CG12069_Dmel KQL-------------------SKDQI-VKTKQ----VSH---VMSEKNVLRSMT-FPNT
PKA-C3_Dmel KIL-------------------AMTEV-IRLKQ----IEH---VKNERNILREIR-HPFV
PRKX_Mmus KIM-------------------SIPDV-IRLKQ----EQH---VQNEKAVLKEIN-HPFL
PKACb_Mmus KIL-------------------DKQKV-VKLKQ----IEH---TLNEKRILQAVE-FPFL
PKACa_Mmus KIL-------------------DKQKV-VKLKQ----IEH---TLNEKRILQAVN-FPFL
kin-1_Cele KIL-------------------DKQKV-VKLKQ----VEH---TLNEKRILQAID-FPFL
F47F2.1_Cele KVL-------------------NIRRV-VDMRQ----TQH---VHNEKRVLLQLK-HPFI
TPK1_Scer KVL-------------------KKEIV-VRLKQ----VEH---TNDERLMLSIVT-HPFI
TPK2_Scer KVL-------------------KKQQV-VKMKQ----VEH---TNDERRMLKLVE-HPFL
TPK3_Scer KTL-------------------KKHTI-VKLKQ----VEH---TNDERRMLSIVS-HPFI
DDB0185224_Ddis KTL-------------------RRETI-VHEKH----KEH---VNNEINIMLNIS-HPYI
pk4_Ddis KIL-------------------NQNKI-IRLRQ----EVH---VCNEKQVLMLTD-NPFI
PKA_Ddis KCL-------------------NKAYV-VQLKQ----VEH---LNSEKSILSSIH-HPFI
17649_Tthe KML-------------------KKTEI-VRLNQ----VEH---INSEKKILQSVK-HPFI
18333_Tthe KMM-------------------KKIEI-VKLKQ----VEH---IKSEKKILSQIK-HPFL
2171_Tthe KML-------------------KKAEI-LRLKQ----VDH---IISENTILSNIN-HPFL
26485_Tthe KVL-------------------KKAEI-IRLKQ----VDH---IINENTILSNLN-HPFI
PRKX_Spur ------------------------------------------------------------
PKA_Spur ------------------------------------------------------------
CC1G_05183_Ccin KVL-------------------RKTVI-VQLRQ----VEH---VNAERYILSRVN-HPFI
CC1G_04466_Ccin KVL-------------------NKERI-VRMKQ----IEH---TNNEMKMLESVQ-HPFI
CC1G_01089_Ccin KTQ-------------------KKKYKRQALPP----EAHMLEKDNERTALALMDWNPFI
AqueK013_Aque AILSAIKGIVDEWDIVGIFLGIDNANI-ERIKSNNSNVDH---RRKEI-IIAWLR-YGNA
AqueK014_Aque KIL-------------------DKQKV-VKLKQ----VEH---TLNEKRILSSIN-FPFV
AqueK015_Aque KIM-------------------SIAEV-IRLKQ----VEH---VNNEKEILTSLQ-HPFI
PKA-1_Smoe KSL-------------------SKASI-VKTKQ----ACE---HSFQKNILQRLD-FPYI
PKA-2_Smoe KSL-------------------SKASI-VKTKQ----ACE---HSFQKNILQRLD-FPYI
GK005_Glam KAM-------------------SKRKI-IALRQ----VAH---INNECSILRVVR-SPFI
GK006_Glam KVL-------------------TKQHV-IESRE----VEH---AISERSILASLN-HPFL
PRKY_Hsap I--R-LF------------WTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSA
PRKX_Hsap I--R-LF------------WTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSA
PKACg_Hsap V--K-LQ------------FSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAA
PKACb_Hsap V--R-LE------------YAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAA
PKACa_Hsap V--K-LE------------FSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAA
Pka-C1_Dmel V--S-LR------------YHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAA
Pka-C2_Dmel I--Y-LV------------DSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAA
CG12069_Dmel V--N-LI------------ASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAA
PKA-C3_Dmel I--S-LE------------WSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAA
PRKX_Mmus I--K-LL------------WTGHDNRFLYMLMEFVPGGELFTYLRNRGRFSSVASVFYAT
PKACb_Mmus V--R-LE------------YSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAA
PKACa_Mmus V--K-LE------------FSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAA
kin-1_Cele V--N-MT------------FSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAA
F47F2.1_Cele V--K-MY------------ASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYAS
TPK1_Scer I--R-MW------------GTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAA
TPK2_Scer I--R-MW------------GTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAA
TPK3_Scer I--R-MW------------GTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAA
DDB0185224_Ddis V--K-TY------------STFNTPTKIHFIMEYAGKKDLFHHLRANKCFTEQTTKLIVA
pk4_Ddis V--K-LY------------STFKDDRYLYFLQEFIPGGELFDYIRANGSLSLYVTQIYAA
PKA_Ddis V--N-LY------------QAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAA
17649_Tthe V--Q-MK------------QSFQDDKYIYMLFEYIQGGELFSRLRKEGRFSNDVGLFYTC
18333_Tthe V--E-LK------------GTFQDEIYIYMLFEFVSGGEIFSRLRKEGRFSNDISLFYIT
2171_Tthe V--N-LSTFYLHQQVIKMIGFTQDDRFLYFVLEYVAGGELFTYLRNKGKLDNPEALFYAA
26485_Tthe V--K-MD------------GFCQDSRYLYLVLEFVSGGELFTYLRSVGRLETNHACFYAA
PRKX_Spur -----------------------------MLLEYACGGELFTYLRNSGRFNNDTGKFYAM
PKA_Spur -----------------------------MVLDYIPGGEMFSHLRRIGRFSEPHSRFYAA
CC1G_05183_Ccin V--D-LF------------ATFQDSLNVYMLMSYVPGGELFTHLRRAQRFTPDVTRFYLA
CC1G_04466_Ccin I--N-LW------------GSFQDSSNLYMVMDFVPGGELFTLLRRSNRFPDPVAKFYAA
CC1G_01089_Ccin A--G-VI------------DILHDVKNIYTILELIPSGTLLSLIKSHAPMPPTIAAFYFA
AqueK013_Aque TRQHLIE------------ALKEDNSYLYMLLEFVSGGEMFSHLRRIGRFSESHSRFYAS
AqueK014_Aque V--N-LE------------FHFKDNSYLYMLLEFVSGGEMFSHLRRIGRFSESHSRFYAS
AqueK015_Aque V--N-LA------------WTHHDNRFLYMLLEYVPGGELFTYLRTAQRFDNATSMFFAS
PKA-1_Smoe V--N-LL------------GYCQDDRCVHLVMEYVCGGEFFTYLRHTGRFDEATSRFYAS
PKA-2_Smoe V--N-LL------------GYCQDDRCVHLVMEYVCGGEFFTYLRHTGRFDEATSRFYAS
GK005_Glam I--R-QY------------GTYQDDKNVYIILDFIQGGELFYHLRRYNKFPLQVVKFFAV
GK006_Glam M--R-LY------------GAFQTPTRLIMVLEYVPGGELFFHLKKKVTFDESYVKLVAA
: .: : : :
PRKY_Hsap EIIC--------------------------------------------------------
PRKX_Hsap EIIC--------------------------------------------------------
PKACg_Hsap QVVL--------------------------------------------------------
PKACb_Hsap QIVL--------------------------------------------------------
PKACa_Hsap QIVL--------------------------------------------------------
Pka-C1_Dmel QIVL--------------------------------------------------------
Pka-C2_Dmel QVAL--------------------------------------------------------
CG12069_Dmel QVFL--------------------------------------------------------
PKA-C3_Dmel EIVS--------------------------------------------------------
PRKX_Mmus EIVC--------------------------------------------------------
PKACb_Mmus QIVL--------------------------------------------------------
PKACa_Mmus QIVL--------------------------------------------------------
kin-1_Cele QIVL--------------------------------------------------------
F47F2.1_Cele EIVC--------------------------------------------------------
TPK1_Scer EVCL--------------------------------------------------------
TPK2_Scer EVIL--------------------------------------------------------
TPK3_Scer EVCL--------------------------------------------------------
DDB0185224_Ddis EIVL--------------------------------------------------------
pk4_Ddis EIVL--------------------------------------------------------
PKA_Ddis EIVL--------------------------------------------------------
17649_Tthe QILL--------------------------------------------------------
18333_Tthe EIYL--------------------------------------------------------
2171_Tthe QVYIFVCDLLSYDNHFETQQINLKIRLSYFLLQQIQQMSQNQSKIFFQNNLRKNTNILPR
26485_Tthe QVTL--------------------------------------------------------
PRKX_Spur EIIS--------------------------------------------------------
PKA_Spur QIVL--------------------------------------------------------
CC1G_05183_Ccin TIIL--------------------------------------------------------
CC1G_04466_Ccin EVAL--------------------------------------------------------
CC1G_01089_Ccin NMFS--------------------------------------------------------
AqueK013_Aque QIVL--------------------------------------------------------
AqueK014_Aque QIVL--------------------------------------------------------
AqueK015_Aque EIVL--------------------------------------------------------
PKA-1_Smoe QVLL--------------------------------------------------------
PKA-2_Smoe QVLL--------------------------------------------------------
GK005_Glam EILL--------------------------------------------------------
GK006_Glam QLVL--------------------------------------------------------
:
PRKY_Hsap ------------------------AIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFA
PRKX_Hsap ------------------------AIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFA
PKACg_Hsap ------------------------AVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFA
PKACb_Hsap ------------------------TFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA
PKACa_Hsap ------------------------TFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA
Pka-C1_Dmel ------------------------AFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFA
Pka-C2_Dmel ------------------------ALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFT
CG12069_Dmel ------------------------ALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFA
PKA-C3_Dmel ------------------------ALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFA
PRKX_Mmus ------------------------AIEYLHSKEIVYRDLKPENILLDREGHIKLTDFGFA
PKACb_Mmus ------------------------TFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA
PKACa_Mmus ------------------------TFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA
kin-1_Cele ------------------------AFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFA
F47F2.1_Cele ------------------------ALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFA
TPK1_Scer ------------------------ALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFA
TPK2_Scer ------------------------ALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFA
TPK3_Scer ------------------------ALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFA
DDB0185224_Ddis ------------------------AIEYLHAENIIYRDLKPENILIDEKGHIKLTDFGFS
pk4_Ddis ------------------------ALEYLHNQDIIYRDLKPENLLIDQYGHIKLTDFGFA
PKA_Ddis ------------------------ALEFLHKQNIVYRDLKPENLLIDNQGHIKITDFGFA
17649_Tthe ------------------------ALQYLHQHDIVYRDLKPENLLIDKEGNIKITDFGFA
18333_Tthe ------------------------ALQYLHSQNIVYRDLKPENLLIDKEGHVKIADFGFA
2171_Tthe QYFYLTNQIKQPKIETKKRYFKVSMFEYLHNKNIVYRDLKPENILIGSDGYLKLTDFGFA
26485_Tthe ------------------------MFEYLHTKNIIYRDLKPENLLIADDGYLKLTDFGFA
PRKX_Spur ------------------------AIDYLHKETIVYRDLKPENILLDSEGHVKLTDFGFA
PKA_Spur ------------------------AFEYLHHLDLIYRDLKPENILIQENGYIAVTDFGFA
CC1G_05183_Ccin ------------------------ALKYLHSFNIIYRDLKPENLLLDSRGYLRLTDFGFA
CC1G_04466_Ccin ------------------------ALNYMHSLDIVYRDLKPENILLNVDGHIKIADFGFA
CC1G_01089_Ccin ------------------------AIEYVHALGLVHRDIKPDNFLLGEDGYLSLTDFGLT
AqueK013_Aque ------------------------AFEYLHYLDIVYRDLKPENLLIDQHGYVKVTDFGFA
AqueK014_Aque ------------------------AFEYLHYLDIVYRDLKPENLLIDQHGYVKVTDFGFA
AqueK015_Aque ------------------------VMDYLHSQYIVYRDLKPENILIDSTGHIKLCDFGFA
PKA-1_Smoe ------------------------AFEHIHGMDIIYRDLKPENLLLDEKGNIKIADFGFA
PKA-2_Smoe ------------------------AFEHIHGMDIIYRDLKPENLLLDEKGNIKIADFGFA
GK005_Glam ------------------------ALGYLHNLGIAYRDLKLENVLVDNTGHIKLADLGFA
GK006_Glam ------------------------AIEYLHDMNIVIRDLKPENILLQANGYIKVTDFGLS
. .:* : **:* :*.:: * : : *:*::
PRKY_Hsap KKL----------VDRT---WTLCGTPEYLAPEVIQS---------------KGHGRAVD
PRKX_Hsap KKL----------VDRT---WTLCGTPEYLAPEVIQS---------------KGHGRAVD
PKACg_Hsap KRVK----------GRT---WTLCGTPEYLAPEIILS---------------KGYNKAVD
PKACb_Hsap KRVK----------GRT---WTLCGTPEYLAPEIILS---------------KGYNKAVD
PKACa_Hsap KRVK----------GRT---WTLCGTPEYLAPEIILS---------------KGYNKAVD
Pka-C1_Dmel KRVK----------GRT---WTLCGTPEYLAPEIILS---------------KGYNKAVD
Pka-C2_Dmel KRVD----------GRT---STLCGTPEYLAPEIVQL---------------RPYNKSVD
CG12069_Dmel KKVE----------TRT---MTLCGTPEYLPPEIIQS---------------KPYGTSVD
PKA-C3_Dmel KKL----------RDRT---WTLCGTPEYIAPEIIQS---------------KGHNKAVD
PRKX_Mmus KKL----------VDRT---WTLCGTPEYLAPEVIQS---------------KGHGRAVD
PKACb_Mmus KRVK----------GRT---WTLCGTPEYLAPEIILS---------------KGYNKAVD
PKACa_Mmus KRVK----------GRT---WTLCGTPEYLAPEIILS---------------KGYNKAVD
kin-1_Cele KRVK----------GRT---WTLCGTPEYLAPEIILS---------------KGYNKAVD
F47F2.1_Cele KELR----------DRT---YTICGTPDYLAPESLAR---------------TGHNKGVD
TPK1_Scer KYVP----------DVT---YTLCGTPDYIAPEVVST---------------KPYNKSID
TPK2_Scer KEVQ----------TVT---WTLCGTPDYIAPEVITT---------------KPYNKSVD
TPK3_Scer KYVP----------DVT---YTLCGTPDYIAPEVVST---------------KPYNKSVD
DDB0185224_Ddis KKTVG--------GKNT---SSVCGTFDYMAPEILNS-S-------------NGHGKPVD
pk4_Ddis KRITE----------NT---KSMCGTPEYIAPEILS--G-------------HGHGKSAD
PKA_Ddis KRV----------EDRT---FTLCGTPEYLAPEIIQS---------------KGHGKAVD
17649_Tthe KKLD---------NDRT---FTLCGTPEYLAPEIIKGSR-------------VGYGKSVD
18333_Tthe KIMD---------SART---YTLCGTPEYLAPEIIQGAK-------------TGYGKSVD
2171_Tthe KYCD----------SRT---YTLCGTPEYLAPEILLN---------------KGHGKPVD
26485_Tthe KVVE----------GRT---YTLCGTPEYLAPEILLN---------------KGHGKAVD
PRKX_Spur KKLV---------DNRT---WTLCGTPEYLAPEIIQS---------------KGHGKAVD
PKA_Spur KRVK----------GRT---WTLCGTPEYLAPEIILS---------------KGYNKAVD
CC1G_05183_Ccin KIVD----------DRT---WTLCGTPEYLAPEIIQS---------------DGHGKAAD
CC1G_04466_Ccin KLCA----------TTT---WTLCGTPDYLAPEIVSQ---------------QRYNKSVD
CC1G_01089_Ccin VPVDDF--------QVD---WVDIGTPLYRPPEMDVRASPAQEKEGDEEEVDLDDRRSVD
AqueK013_Aque KRVK----------GRT---WTLCGTPEYLAPEIILS-----------------------
AqueK014_Aque KRVK----------GRT---WTLCGTPEYLAPEIILS---------------KGYNRAVD
AqueK015_Aque KRLA---------DRRT---YTLCGTPEYLAPEIIQG---------------KGHGREVD
PKA-1_Smoe KQID----------RRT---YTLCGTPDYLAPEIILN---------------KGHGKPVD
PKA-2_Smoe KQID----------RRT---YTLCGTPDYLAPEIILN---------------KGHGKPVD
GK005_Glam KRLVEKNADGDTVSQLT---FSIVGTPEYLAPEIIRS---------------TGHDMSAD
GK006_Glam KQNL----------SMTLGAKTMAGTSEYFSPEQVQN---------------CGHGKGVD
** * .**
PRKY_Hsap WWALGILIFEMLSGFPPFFD--DN-P--FGIYQKILAG--KLYFPR-HLD-----FHVKT
PRKX_Hsap WWALGILIFEMLSGFPPFFD--DN-P--FGIYQKILAG--KIDFPR-HLD-----FHVKD
PKACg_Hsap WWALGVLIYEMAVGFPPFYA--DQ-P--IQIYEKIVSG--RVRFPS-KLS-----SDLKH
PKACb_Hsap WWALGVLIYEMAAGYPPFFA--DQ-P--IQIYEKIVSG--KVRFPS-HFS-----SDLKD
PKACa_Hsap WWALGVLIYEMAAGYPPFFA--DQ-P--IQIYEKIVSG--KVRFPS-HFS-----SDLKD
Pka-C1_Dmel WWALGVLVYEMAAGYPPFFA--DQ-P--IQIYEKIVSG--KVRFPS-HFG-----SDLKD
Pka-C2_Dmel WWAFGILVYEFVAGRSPFAIHNRD-V--ILMYSKICIC--DYKMPS-YFT-----SQLRS
CG12069_Dmel WWAFGVLVFEFVAGHSPFSAHNRD-V--MSMYNKICEA--DYKMPS-YFS-----GALRH
PKA-C3_Dmel WWALGVLIYEMLVGYPPFYD--EQ-P--FGIYEKILSG--KIEWER-HMD-----PIAKD
PRKX_Mmus WWALGILIFEMLSGFPPFFD--DN-P--FGIYQKILAC--KIDFPR-QLD-----FTSKD
PKACb_Mmus WWALGVLIYEMAAGYPPFFA--DQ-P--IQIYEKIVSG--KVRFPS-HFS-----SDLKD
PKACa_Mmus WWALGVLIYEMAAGYPPFFA--DQ-P--IQIYEKIVSG--KVRFPS-HFS-----SDLKD
kin-1_Cele WWALGVLIYEMAAGYPPFFA--DQ-P--IQIYEKIVSG--KVKFPS-HFS-----NELKD
F47F2.1_Cele WWALGILIYEMMVGKPPFRG--KT-T--SEIYDAIIEH--KLKFPR-SFN-----LAAKD
TPK1_Scer WWSFGILIYEMLAGYTPFYD--SN-T--MKTYEKILNA--ELRFPP-FFN-----EDVKD
TPK2_Scer WWSLGVLIYEMLAGYTPFYD--TT-P--MKTYEKILQG--KVVYPP-YFH-----PDVVD
TPK3_Scer WWSFGVLIYEMLAGYTPFYN--SN-T--MKTYENILNA--ELKFPP-FFH-----PDAQD
DDB0185224_Ddis WWALGVVVYELVTGKLPFSN--SK-E--SLLNRKADFQ--LIFQNS-YLS-----DEIKD
pk4_Ddis WWSLGILIYEMLVGVPPFVS--EGSQ--NDIFRLIREA--RIQVPP-EVD-----QVARD
PKA_Ddis WWALGILIFEMLAGYPPFYD--DD-T--FAIYNKILAG--RITFPL-GFD-----VDAKD
17649_Tthe WWALGILVFEMLSGYPPFYD--NE-P--IGIYKKIIAG--IIEFPR-FFD-----NKAKD
18333_Tthe WWALGVLIFEMLSGHPPFYD--CD-P--MGIYQKIVNS--VINFPE-FFS-----LRAKD
2171_Tthe WWCLGILIYEMLAGIDPFND--ED-P--MAIYQKILKG--KVKFPR-NFD-----KNAKS
26485_Tthe WWTLGILIYEMNAGIDPFTD--ED-P--MAIYQKILKG--KVKFPR-NFD-----KNAKS
PRKX_Spur WWALGILIYEMLAGYPPFYD--EN-P--FGIYEKILAC--KIDWPQ-SIG-----SKPKK
PKA_Spur WWALGVLIYEMAAGYPPFFA--DQ-P--IQIYEKIVSG--KVRFPS-HFS-----ADLKD
CC1G_05183_Ccin WWACGVLCYEMLVGYPPFFD--ES-P--YGIYEKILNG--QIHWPR-HID-----RLSKD
CC1G_04466_Ccin WYALGVLIFEMLSGLPPYHQ--PE-PNHLALYEKIMRGPKNIRWPAAAFN-----ENATD
CC1G_01089_Ccin WYSSAVVLYEMVTRTVPFYG--RT-K--LQTNALKVEK--KYSFPK-DIRI---GSHFKD
AqueK013_Aque ------------------------------------------------------------
AqueK014_Aque WWAMGVLIYEMAAGYPPFFA--DQ-P--IQIYEKIVSG--KVRFPS-HFT-----ADLKD
AqueK015_Aque WWALGILVYEMLVGYPPFFD--EH-P--FRIYEKILEG--KVDWPK-VIS-----STAKD
PKA-1_Smoe WWAFGVLIYEMLAGYPPFYD--DD-A--IGTYQKILAG--KLQFPG-HFSRRQTSCSAKD
PKA-2_Smoe WWAFGVLIYEMLAGYPPFYD--DD-A--IGTYQKILAG--KLQFPG-HFSRRQISCSAKD
GK005_Glam WWAFGVLIYEMLTGSPPFFD--DN-P--DMTCKKILGG--KITFAS-GFD-----KAAKD
GK006_Glam MWALGTIIYELLTGSPPFYS--DD-K--RAMFRKIIGE--QPKMPS-YFK-----DDLKD
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap LIKKLLVVDRTRRLGN-MK--------NGANDVKHHRWFRSVDWEAVPQR-KLKPPI---
PKACg_Hsap LLRSLLQVDLTKRFGN-LR--------NGVGDIKNHKWFATTSWIAIYEK-KVEAPF---
PKACb_Hsap LLRNLLQVDLTKRFGN-LK--------NGVSDIKTHKWFATTDWIAIYQR-KVEAPF---
PKACa_Hsap LLRNLLQVDLTKRFGN-LK--------NGVNDIKNHKWFATTDWIAIYQR-KVEAPF---
Pka-C1_Dmel LLRNLLQVDLTKRYGN-LK--------AGVNDIKNQKWFASTDWIAIFQK-KIEAPF---
Pka-C2_Dmel LVESLMQVDTSKRLGN-SN--------DGSSDVKSHPWFQGVDWFGILNQ-EVTAPY---
CG12069_Dmel LVDHLLQVDLSKRFGN-LI--------NGNRDIKEHEWFKDVEWIPLLNQ-TVNAPY---
PKA-C3_Dmel LIKKLLVNDRTKRLGN-MK--------NGADDVKRHRWFKHLNWNDVYSK-KLKPPI---
PRKX_Mmus LIKKLLVVDRTRRLGN-MK--------NGAEDIKRHRWFRGVEWESVPQR-KLKPPI---
PKACb_Mmus LLRNLLQVDLTKRFGN-LK--------NGVSDIKTHKWFATTDWIAIYQR-KVEAPF---
PKACa_Mmus LLRNLLQVDLTKRFGN-LK--------NGVNDIKNHKWFATTDWIAIYQR-KVEAPF---
kin-1_Cele LLKNLLQVDLTKRYGN-LK--------NGVADIKNHKWFGSTDWIAIYQK-KITPPSFSK
F47F2.1_Cele LVKKLLEVDRTQRIGC-MK--------NGTQDVKDHKWFEKVNWDDTLHL-RVEPPI---
TPK1_Scer LLSRLITRDLSQRLGN-LQ--------NGTEDVKNHPWFKEVVWEKLLSR-NIETPY---
TPK2_Scer LLSKLITADLTRRIGN-LQ--------SGSRDIKAHPWFSEVVWERLLAK-DIETPY---
TPK3_Scer LLKKLITRDLSERLGN-LQ--------NGSEDVKNHPWFNEVIWEKLLAR-YIETPY---
DDB0185224_Ddis FIFQLLSVDPSKRLGT-FD--------S--CSIRNHKWFSDINWLHLESKYQIDGPL---
pk4_Ddis LIEKLVVTDVEKRLGS-LE--------GGIEDIKNHPFFGAINWNSIQNR-E-SAPL---
PKA_Ddis LIKRLLTADRTRRLGA-LK--------DGALDVKNHRWFSDINWERLYQR-RDNGPF---
17649_Tthe LIRKLLNPDLNYRLGV-H---------DKGQSVSKHKWFRGVDWESVFNK-DIPAPW---
18333_Tthe LVRKLLNPNIESRLGC-QDQILSNVIDQDGNSIKNHKWFKGVNWDKIYHK-QIPSPW---
2171_Tthe LVKHLLVADLTKRYGN-LK--------GGVNDIKTHRWFADMDWDALFHK-KIPPTY---
26485_Tthe LVKHLLVADLSKRYGN-LK--------NGANDIKNHRWFSSIDWAQLLSK-KLPVPY---
PRKX_Spur LIEGLLVIDRTKRLGC-MR--------AGSNDIKNSDWFESIDWENVRQR-QLKPPI---
PKA_Spur ILRSLLQVDLTKRYGN-LK--------AGVADIKLHKWFQSTDWIAIYQQ-RVDAPF---
CC1G_05183_Ccin LIKSFLNPDRTKRLGN-ML--------GGPQDILDHPWFRGVDWDALERR-EINAPI---
CC1G_04466_Ccin LILKLMEGDPSRRYGN-LR--------HGAGDVFAHPWFREVDWDRLAAR-EITAPY---
CC1G_01089_Ccin LIKSLLDPEPSNRP--------------RPAEIQENKWLSRIDWDKLHEK-QYLPPH---
AqueK013_Aque ------------------------------------------------------------
AqueK014_Aque LLRNLLQVDLTKRFGN-LK--------NGVQDIKGHSWFSSTEWISIYQR-KIDAPF---
AqueK015_Aque LIKKLLVKDVTRRLGS-LK--------DGVDDVKQHKWFRGVDWDAVLMR-KSLPLI---
PKA-1_Smoe LVRRLLTADLTKRIGC-LK--------DGVDEIKNHSWFANVKWDNVLAK-KDTPPI---
PKA-2_Smoe LVRRLLTADLTKRIGC-LK--------DGVDEIKNHSWFANVKWDNVLAK-KDTPPI---
GK005_Glam LIIRLLNPDKTRRLGASIN--------NGTADIMKHAFFSGVNWSWFEKK-VVKAPI---
GK006_Glam LLKGLLEKKPRSRLGC-RKE------NGGIKELKGHPWFNGINWDKLYRK-EYTIPY---
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap -----------VPKI-AGD----------------------------------GDTSNFE
PKACg_Hsap -----------IPKY-TGP----------------------------------GDASNFD
PKACb_Hsap -----------IPKF-RGS----------------------------------GDTSNFD
PKACa_Hsap -----------IPKF-KGP----------------------------------GDTSNFD
Pka-C1_Dmel -----------IPRC-KGP----------------------------------GDTSNFD
Pka-C2_Dmel -----------QPTI-SGA----------------------------------EDLSNFE
CG12069_Dmel -----------VPNI-SNP----------------------------------EDISNFD
PKA-C3_Dmel -----------LPDV-HHD----------------------------------GDTKNFD
PRKX_Mmus -----------VPKL-SGD----------------------------------GDISNFE
PKACb_Mmus -----------IPKF-RGS----------------------------------GDTSNFD
PKACa_Mmus -----------IPKF-KGP----------------------------------GDTSNFD
kin-1_Cele GESNGRLFEALYPRV-DGP----------------------------------ADTRHFV
F47F2.1_Cele -----------VPTL-YHP----------------------------------GDTGNFD
TPK1_Scer -----------EPPIQQGQ----------------------------------GDTSQFD
TPK2_Scer -----------EPPITSGI----------------------------------GDTSLFD
TPK3_Scer -----------EPPIQQGQ----------------------------------GDTSQFD
DDB0185224_Ddis -----------STLN-SFINCDFNINLLKKSKSYTEQQQQQQQLPQQQQQQQQNN-QLFN
pk4_Ddis -----------KPRI-RPL----------------------------------KH-HLMD
PKA_Ddis -----------IPKI-QHQ----------------------------------GDSSNFE
17649_Tthe -----------TPQL-RNE----------------------------------QDASCFE
18333_Tthe -----------IPQL-KSI----------------------------------DDVSYFE
2171_Tthe -----------KPVV-KGK----------------------------------GDTSNYS
26485_Tthe -----------KPVV-KAP----------------------------------NDTSNFS
PRKX_Spur -----------VPKL-SHA----------------------------------GDTSNFD
PKA_Spur -----------VPRV-KGP----------------------------------GDASQFD
CC1G_05183_Ccin -----------IPRT-TSV----------------------------------DDTRHFL
CC1G_04466_Ccin -----------LPRI-SGD----------------------------------GDASAFD
CC1G_01089_Ccin -----------LPKNP-SA----------------------------------SK-GMWH
AqueK013_Aque ------------------------------------------------------------
AqueK014_Aque -----------VPKT-KGA----------------------------------GDPSNFD
AqueK015_Aque -----------IPRV-SHP----------------------------------GDTRNFE
PKA-1_Smoe -----------RPKV-AVC----------------------------------LY-----
PKA-2_Smoe -----------RPKV-AVC----------------------------------VY-----
GK005_Glam -----------VPKL-TDP----------------------------------ADTANYE
GK006_Glam -----------KPTI-TDN----------------------------------LDLSNFD
PRKY_Hsap ------------------------------------------------------------
PRKX_Hsap TY-PEN--DWD------TAA----------------------------------------
PKACg_Hsap DY-EEE--EL--------RI----------------------------------------
PKACb_Hsap DY-EEE--DI--------RV----------------------------------------
PKACa_Hsap DY-EEE--EI--------RV----------------------------------------
Pka-C1_Dmel DY-EEE--AL--------RI----------------------------------------
Pka-C2_Dmel NF-EFK--DRY------K------------------------------------------
CG12069_Dmel KV-SDK--PRP------K------------------------------------------
PKA-C3_Dmel DY-PEK--DWK------PAK----------------------------------------
PRKX_Mmus TY-PES--ELD------KTP----------------------------------------
PKACb_Mmus DY-EEE--EI--------RV----------------------------------------
PKACa_Mmus DY-EEE--EI--------RV----------------------------------------
kin-1_Cele EE-VQE--PTE------FVI----------------------------------------
F47F2.1_Cele DY-EED--TTG------GPL----------------------------------------
TPK1_Scer KY-PEE--DIN------YGV----------------------------------------
TPK2_Scer QY-PEE--QLD------YGI----------------------------------------
TPK3_Scer RY-PEE--EFN------YGI----------------------------------------
DDB0185224_Ddis QT-LQQ--Q-N------FNF-H----------PIQP-----QQQQQQQFFNFQFNNNNFN
pk4_Ddis ER-DEE--D-R------ISA-N----------FIKP-----D------------------
PKA_Ddis MY-DEE--EMV------EEPPS-------------------S------------------
17649_Tthe KY-PDS--QEG------A-R----------------------------------------
18333_Tthe KY-PES--KDK------Q-E----------------------------------------
2171_Tthe SY-PDS--TEL------PKP----------------------------------------
26485_Tthe SY-PES--DTH------SPA----------------------------------------
PRKX_Spur EY-PEE--NWE------TDA---------------------S------------------
PKA_Spur EY-EEE--AL--------KI----------------------------------------
CC1G_05183_Ccin HL-PPP--TAE------EIPGL-------------VGQDLPQ------------------
CC1G_04466_Ccin KY-PED--NVQ------NTY-G-------------------L------------------
CC1G_01089_Ccin RQ-PLPNPQDVPGLKVVYPP-S-------------------H------------------
AqueK013_Aque ------------------------------------------------------------
AqueK014_Aque DY-KEE--VL--------RI----------------------------------------
AqueK015_Aque RY-P--------------------------------------------------------
PKA-1_Smoe ------------------------------------------------------------
PKA-2_Smoe ------------------------------------------------------------
GK005_Glam DY-LDE--NGN------FEE-DEIDYENLGSDAAELGLAEIP------------------
GK006_Glam KSFTEL--DFD------FSS-E-------PLYK--------R------------------
PRKY_Hsap ----------------------GR------------------------------------
PRKX_Hsap -------------PVPQKDLEIFK------------------------------------
PKACg_Hsap -------------SINEKCAKEFS------------------------------------
PKACb_Hsap -------------SITEKCAKEFG------------------------------------
PKACa_Hsap -------------SINEKCGKEFS------------------------------------
Pka-C1_Dmel -------------SSTEKCAKEFA------------------------------------
Pka-C2_Dmel -------------SRINRHPELFA------------------------------------
CG12069_Dmel -------------AKTMRHEEAFA------------------------------------
PKA-C3_Dmel -------------AVDQRDLQYFN------------------------------------
PRKX_Mmus -------------SVSDKDLETFK------------------------------------
PKACb_Mmus -------------SITEKCGKEFC------------------------------------
PKACa_Mmus -------------SINEKCGKEFT------------------------------------
kin-1_Cele -------------AATPQLEELFV------------------------------------
F47F2.1_Cele --------------CSQRDRDLFA------------------------------------
TPK1_Scer -------------QGEDPYADLFR------------------------------------
TPK2_Scer -------------QGDDPYAEYFQ------------------------------------
TPK3_Scer -------------QGEDPYMDLMK------------------------------------
DDB0185224_Ddis NNNNNNNNFNEACTSNTCGGTTAS------------------------------------
pk4_Ddis -------------LLERRKNEFFS------------------------------------
PKA_Ddis -------------NYVDPYAHLFK------------------------------------
17649_Tthe -------------SLPRDLQHLFE------------------------------------
18333_Tthe -------------NPTKEIQKLFA------------------------------------
2171_Tthe ---------------IKPADDPFI------------------------------------
26485_Tthe ---------------LKPADDPFL------------------------------------
PRKX_Spur -------------PVKSDVLKLFK------------------------------------
PKA_Spur -------------SLTEKCVKEFA------------------------------------
CC1G_05183_Ccin -------------PRFDPINYHFL------------------------------------
CC1G_04466_Ccin -------------PALDPYGVVFPDF----------------------------------
CC1G_01089_Ccin -------------ILHDNRFPPKL------------------------------------
AqueK013_Aque ------------------------------------------------------------
AqueK014_Aque -------------AAAEKFPKEFA------------------------------------
AqueK015_Aque -----------------------E------------------------------------
PKA-1_Smoe -----------------------F------------------------------------
PKA-2_Smoe -----------------------F------------------------------------
GK005_Glam -------------GTQEEIDALFV------------------------------------
GK006_Glam -------------EHNADDDQIFQDFCKAYATNAEDEQKTNCPTDNDESNTFTQSGQINY
PRKY_Hsap --------------------------MM
PRKX_Hsap --------------------------NF
PKACg_Hsap --------------------------EF
PKACb_Hsap --------------------------EF
PKACa_Hsap --------------------------EF
Pka-C1_Dmel --------------------------EF
Pka-C2_Dmel --------------------------NF
CG12069_Dmel --------------------------DF
PKA-C3_Dmel --------------------------DF
PRKX_Mmus --------------------------NF
PKACb_Mmus --------------------------EF
PKACa_Mmus --------------------------EF
kin-1_Cele --------------------------EF
F47F2.1_Cele --------------------------EW
TPK1_Scer --------------------------DF
TPK2_Scer --------------------------DF
TPK3_Scer --------------------------EF
DDB0185224_Ddis --------------------------IF
pk4_Ddis --------------------------NF
PKA_Ddis --------------------------DF
17649_Tthe --------------------------DF
18333_Tthe --------------------------DF
2171_Tthe --------------------------NW
26485_Tthe --------------------------DW
PRKX_Spur --------------------------DF
PKA_Spur --------------------------DF
CC1G_05183_Ccin --------------------------EF
CC1G_04466_Ccin -----------------------EYTGS
CC1G_01089_Ccin --------------------------DL
AqueK013_Aque ---------------------------K
AqueK014_Aque --------------------------DF
AqueK015_Aque --------------------------DG
PKA-1_Smoe --------------------------LI
PKA-2_Smoe --------------------------LI
GK005_Glam -------------------------GFK
GK006_Glam DSADAQDSTKGLPACLVDDDDTDMPPPP