Protein (view, download) , Domain (view, download)
PDK1_Hsap        MARTTSQLYDAV------------------------------------------------
Pk61C_Dmel       MAKEKASATVSL-GESNFRD------INLKDLAVVVEAASRLHHQQNVCGCGAV--S-ST
PDK1_Mmus        MARTTSQLYDAV------------------------------------------------
pdk-1_Cele       MEDLTPTNTSL-------------------------------------DT------T-TT
PKH2_Scer        MYFDKDNSMSP-----RPLLPSDEQKLNINLLT-KKEKFSHL--DPHYDAKATPQ-RSTS
PKH1_Scer        MGNRSLTEADHALLS-KPLVPTSAE-------------------HTQTQEYPRPF-VDGS
W04B5.5_Cele     MEVPENLK----------------------------------------------------
YDR466W_Scer     MTSR--------------------------------------------------------
Pdk1A_Ddis       MENIVITNTSGG------------------------------------GGGGV-------
Pdk1B_Ddis       MINGRYQKEDVVNNN-NN--------LNLNLIEKTLNDLT-IKNNTNINNNNTNNK----
8643_Tthe        MIAKQIHEIEFAQIK-LFI-Q--------------------I--H-------------QS
PDK1_Spur        MPSLSTQSSKTS-LS----WPGHPMAAGSYMLQAAQEPIL--VTHTNFQGTAPPSRS-CS
CC1G_15192_Ccin  MSVKAAT-----------------------------------------------------
AqueK012_Aque    MAAPQEPP----------------------------------------------------
PDK1-2_Smoe      MAAGEEECA-----------PST----------------------------------A--
PDK1-1_Smoe      MAAGEEECA-----------PST----------------------------------A--
GK002_Glam       MPFEQQS-----------------------------------------------------
                 *

PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       ENNN--------------------------------------------------------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       NNDT--------------------------------------------------------
PKH2_Scer        NRNVGDLLLEKRTAKPMIQKALTNTDNFIEMY----------------------------
PKH1_Scer        NSQSGS-ELQASPQGQFGEKALTSTNRFIPLA----------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ----------------------------NTNYYNNNNFNNNNNNNNNNNNNNNNINNNNN
8643_Tthe        N-----------------------TNKFYS------------------------------
PDK1_Spur        ANSD--------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       ------------------------------------------------------------


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       ---------------------------------------------------------N--
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       ---------------------------------------------------------T--
PKH2_Scer        -------------------------------------------------------HNQ--
PKH1_Scer        ------------------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       NNKYLNNSHNNNNNNNNNNNNNNNNNNNNNNNEINNNNNNVLSHSSLSGKGGSTTY----
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        ---------------------------------------------------------RAR
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       ------------------------------------------------------------


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       ------------------------------------------------------------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       ------------------------------------------------------------
PKH2_Scer        ------------------------------------------------------------
PKH1_Scer        ------------------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ---------ETTSYTTSITSSRDTGT----------------------------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        STASGHARSPTTDRTFSHTSTRNTSNGTHYRCFCTAAVLCSLLAVSLLIAGLVFLLDGVA
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       ------------------------------------------------------------


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       ------------------------------------------------------------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       ------------------------------------------------------------
PKH2_Scer        -----------------------------QR-----KNLDDDTIKEVMINDENGKTVAST
PKH1_Scer        -------------------------------------------------NDDP-------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ------------------------------------------------------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        STSRTMGIILVVVATLVTICALVIWRYTCQRHKIVKETQQDVTLKSVKSN----------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       ------------------------------------------------------------


PDK1_Hsap        --------------------------------------PIQSSVVLCSCPSPSMV-----
Pk61C_Dmel       ------------------------------------------------------S-----
PDK1_Mmus        --------------------------------------PIQSSVVLCSCPSPSMV-----
pdk-1_Cele       ------------------------------------------------------S-----
PKH2_Scer        NDGR---------------YDNDYD-----NND------I--------------------
PKH1_Scer        ------------------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       --------------------------------------PSS------STDPPNN------
Pdk1B_Ddis       --------------------------------------IST------SYESS--------
8643_Tthe        ------------------------------------------------------FNDDLQ
PDK1_Spur        NSPSYVTKSICSNFKSSSFVL--REMASVNSAEFSECKPIIHSPVSRSCHQEAMS-----
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       ------------------------------------------------------------


PDK1_Hsap        ------RTQTES--ST---PPGIPG--G-S--RQGPAMDGTAA-----------------
Pk61C_Dmel       ------RYGSSKYLTNGHTSPLAAA--V-A--SNSSS-VATTP---HCRMLHNCSLQQYQ
PDK1_Mmus        ------RSQTEP--GS---SPGIPS--GVS--RQGSTMDGTTA-----------------
pdk-1_Cele       ------DREAAP--TTL---NLTPT--A-S--ESENS-----------------------
PKH2_Scer        ------NDQKTL--DN---IAGSPH--M-EKNRNKVKIEHDSS-----------------
PKH1_Scer        ---------GMQ--HE---MGLDPS--M-RRRREEWAERGAAKIVKD-------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       -----------------------------T----TTT-TATAS-----AI----------
Pdk1B_Ddis       -----------------------------S----SSS-SSSSS-----SL-YD---DDEY
8643_Tthe        IFTLSVREKKQE--FS---IKMNQG--I-R--RSKRYCKVETK-----------------
PDK1_Spur        ------KHKSTD--SQ---PISSSGNSGSS--SKASN-NQFAS-----------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------S-----------------
PDK1-1_Smoe      ------------------------------------------S-----------------
GK002_Glam       ------------------------------------------------------------


PDK1_Hsap        ---------------------------------------------------EPRPGAG--
Pk61C_Dmel       NDIRQQTEILDMLRQQHQQGYQSQQQ-------------------------QQQPQQQQE
PDK1_Mmus        ---------------------------------------------------EARPSTN--
pdk-1_Cele       ----------------------------------------------------LSPVTA--
PKH2_Scer        ---------------------------------------------------SQKPI----
PKH1_Scer        ---------------------------------------------------VVDPA----
W04B5.5_Cele     -----------------------------------------------------NPQ----
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       -----------------------------------------------DLNMSLSPFLSS-
Pdk1B_Ddis       SDYSDSSDSIDS-YVNHRQALSKSQQQQHLQQQQDQPQPLHSSMGAISNEKPPSPTNQQQ
8643_Tthe        ---------------------------------------------------RIKKSDQ--
PDK1_Spur        ---------------------------------------------------S--PRSA--
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ---------------------------------------------------SCKPG----
PDK1-1_Smoe      ---------------------------------------------------SCKPG----
GK002_Glam       ------------------------------------------------------------


PDK1_Hsap        -----------------SL----QHAQPPPQPRKKRPEDFKFGKILGEGSFSTV------
Pk61C_Dmel       QQQQQ----------EQSQ----QQQQLQNPAPRRSPNDFIFGRYIGEGSYSIV------
PDK1_Mmus        ---------------PLQQ----HPAQLPPQPRKKRPEDFKFGKILGEGSFSTV------
pdk-1_Cele       ----------------EDL----IAKSIKEGCPKRTSNDFMFLQSMGEGAYSQV------
PKH2_Scer        -----------------AK----ESSKAQKNIIKKGIKDFKFGSVIGDGAYSTV------
PKH1_Scer        ------------------------TGELTKHVVKMGIKDFKFGEQLGDGSYSSV------
W04B5.5_Cele     -------------------------NARREGSNMKCLADYSVEKEVGEGSFSTV------
YDR466W_Scer     ---------------------------------KRSPHDFIFKEELGHGSYSTV------
Pdk1A_Ddis       ---------------P--S----LSSPSIQSAKKKTIEDFIIGKVLGEGSYGAV------
Pdk1B_Ddis       Q--QQHHHPKHNIELP--KTSSFGLQPNSSIPHKKSRSDFDFIRTIGKGAYGKV------
8643_Tthe        ---------------LTNF----NLSKHGWQAAILRNQLFSNNKNLGRGSFGEV------
PDK1_Spur        ----------------TSP----SPSPSSTSILKKKRADFRFGTILGEGSYSEV------
CC1G_15192_Ccin  -----------------------------VQRQPACLDDFDVGEEIAWGSLATI------
AqueK012_Aque    -----------------KL----EAKSPPAEPQKKSREDFNFDRIIGEGSYSTV------
PDK1-2_Smoe      -----------------SK----LTFRA--PQQPYTYQDFAYGRLLGMGSYSKV------
PDK1-1_Smoe      -----------------SK----LTFRA--PQQPYTYQDFAYGRLLGMGSYSKVANSSCI
GK002_Glam       --------------------------------TTGDFPGFDVIDFLGEGSYGKV------
                                                        :     :. *: . :

PDK1_Hsap        ------------VLARELA----TSREYAIKILEKRHIIKENKVPYVTRERDVMSRL---
Pk61C_Dmel       ------------YLAVDIH----SRREYAIKVCEKRLILRERKQDYIKREREVMHQMT--
PDK1_Mmus        ------------VLARELA----TSREYAIKILEKRHIIKENKVPYVTRERDVMSRL---
pdk-1_Cele       ------------FRCREVA----TDAMFAVKVLQKSYLNRHQKMDAIIREKNILTYLSQE
PKH2_Scer        ------------MLATSIDT----KKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLN--
PKH1_Scer        ------------VLATARDS----GKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLN--
W04B5.5_Cele     ------------YLARRKEPKNDENPEVALKICLKRLILKNKMVPYIHREKEALALISRE
YDR466W_Scer     ------------FKALDKKS---PNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQ-
Pdk1A_Ddis       ------------VLGTEKE----TQQQYAIKILEKKQIIKENKIKYVQIEKEIFCKS---
Pdk1B_Ddis       ------------KLVIEKE----TQLIFASKILNKKLIIKEKKAKYVNTEKTILDSL---
8643_Tthe        ------------ILAKNKS----NNEFCAIKILEKSYLAREKKQYQVFIEKEVLTHI---
PDK1_Spur        ------------VLATEIA----TGNQYAIKVLEKRHIIREKKEKYVLREKEVLSRL---
CC1G_15192_Ccin  ------------VEGVHKK----SGKLFAIKMLNKMQLSKKKMVRSAMLEKDALIALSS-
AqueK012_Aque    ------------SSC------------ALVKILDKRHIIKEKKVQYVSREKDVLARI---
PDK1-2_Smoe      ------------VRAKKKDS----GAEFALKIMDKKHITKENKVAYVKMERLILDHL---
PDK1-1_Smoe      FPFFIFLPLFQVVRAKKKDS----GAEFALKIMDKKHITKENKVAYVKMERLILDHL---
GK002_Glam       ------------YRAIDAE----TGLEVGLKVINRKALENDKLLYTLDREVVALRTAQN-
                                               *:  :  : ..        *   :

PDK1_Hsap        --DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKI--GSFDETCTRFYTAEIVSAL
Pk61C_Dmel       --NVPGFVNLSCTFQDQRSLYFVMTYARKGDMLPYINRV--GSFDVACTRHYAAELLLAC
PDK1_Mmus        --DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKI--GSFDETCTRFYTAEIVSAL
pdk-1_Cele       CGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHF--GSFDMLTSKFFASEILTGL
PKH2_Scer        --NSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKY--GSLDETCARYYAAQIIDAI
PKH1_Scer        --GTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKY--GSLNETCARYYASQIIDAV
W04B5.5_Cele     ENAHPGIVTLYATFQDSESLYFVLEYAKYGDLCTLMQKQPDSKFNVADSRYYAANLLSAL
YDR466W_Scer     -KHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKM--GTFNDIWTRHFTAQLIDAL
Pdk1A_Ddis       --NHPNIVKLFFTFRSEQCLYYVLELCSQGDLLHQIKKV--GSFDYRSCQYYVAEIISGL
Pdk1B_Ddis       --DNPNIVKLFYTFQDENNLYFILEYCPNGDLLGALKKA--GCFSIDVVRFYAAEILIAL
8643_Tthe        --RFDGIIQLLGSFKDNQFLYFVLEYCEGGEFSSYLQHNF-KFLNQDTIKFYAAEIVYIL
PDK1_Spur        --DHPFFVRLYFTFQDNYKLYFGLSLAKRGELLPYIKKL--GSFDESSSRFYTSEIILAL
CC1G_15192_Ccin  -HPHPGIVRLHYCFQDAANLYFVLDLAPNGDLKSLTLKT--GSLSLECARYYTAQMIDAI
AqueK012_Aque    --DHPFFVKLYFTFQDKDNLYFGLSFAEQGELLDYLRKV--GAFDENATRFYTSEIVIAL
PDK1-2_Smoe      --DHPGVVRLFFTFQDTHNLYMGLECCHGGELFDQIRRK--GRLSLEEARFYAAEIVDVL
PDK1-1_Smoe      --DHPGVVRLFFTFQDTHNLYMGLECCHGGELFDQIRRK--GRLSLEEARFYAAEIVDVL
GK002_Glam       -KNLTNIIRLYSKTDKNDFTTLILEYASLGDLSSLIKCY--RVLPEDWTRFLIAEIILGL
                       .  *     .       :     *::           :     :.  ::::

PDK1_Hsap        EYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES-------------------
Pk61C_Dmel       EHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAKVMTAHERALATEHCS----EQRR--
PDK1_Mmus        EYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES-------------------
pdk-1_Cele       QFLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQEGFTDA----NQAS--
PKH2_Scer        DYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSV----------------
PKH1_Scer        DSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTA---------------
W04B5.5_Cele     EHIHKLGIIHRDVKADNLLVKSDGRIMLTDFGSSKFLSDYQKIQE---------------
YDR466W_Scer     EFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAK-------------
Pdk1A_Ddis       EHLHSLGIVHRDLKPENILMSSDLHVKITDFGTGKILPPPQSSQQQQQQQ----QQQQ--
Pdk1B_Ddis       EYLHGKGIAHRDLKPENILLGKNQHLKLSDFGSAKQLSIGSHH-----------------
8643_Tthe        ENLHKNGIIHRDLKPENLMLTKDNHLKIIDFGTCGFDRRIPEDLFQKINN----IKK---
PDK1_Spur        EYLHSMGIIHRDLKPENILLNEKMHIQITDFGTAKIIGADDK------------------
CC1G_15192_Ccin  NLMHEAGVAHRDIKPENCLLDKSMRIKIADFGSAYVTSTPL-------------------
AqueK012_Aque    EYLHGKGIIHRDLKPENILLNKDMHIQITDFGTAKIFESDE-------------------
PDK1-2_Smoe      EYIHGQGLIHRDLKPENLLLTADGHIKVADFGSAKVTTPLQNGL----------------
PDK1-1_Smoe      EYIHGQGLIHRDLKPENLLLTADGHIKVADFGSAKVKYLSFSCSFLV-------------
GK002_Glam       EGLHSIGYCHRDIKPSNILLTRGGHVRIADFGTSKQLPLDEVSMAIGTKSFPPSAYMSTS
                 : :*     ***:*..* ::    :  : ***:

PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       --S---NSDEDDEDSDRLEN-----EDEDFYDRDSEELDDGDDEQQQEEMDSPR------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       --S--RSSDSGSPPPT------------RF---------------------YS-------
PKH2_Scer        ----------------------------------------------------S-------
PKH1_Scer        ---------------------------------------------------DG-------
W04B5.5_Cele     ---------------------------------------------------NP-------
YDR466W_Scer     --F------------------------------------------------NS-------
Pdk1A_Ddis       --Q--LPTNSSGNLSSLLNNVNNLSVSTDLTQQQQNRTSSVDSASTTDSMI--SPNLQPT
Pdk1B_Ddis       ------------------------------------------------------------
8643_Tthe        --KFPQET-------------------------------------------DP-------
PDK1_Spur        ------------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      --S------------------------------------------------FS-------
GK002_Glam       SAA--ASNDSQGTLQ------------------------------------KK-------


PDK1_Hsap        -----------------------------------------------------KQARANS
Pk61C_Dmel       ----------------------------------------------HRQR-RYNRHRKAS
PDK1_Mmus        -----------------------------------------------------KQARANS
pdk-1_Cele       -----------------------------------------------DEE-EENTARRTT
PKH2_Scer        -----------------------------------------------KPE-YDLSTRSKS
PKH1_Scer        -----------------------------------------------KPY-FDLYAKSKS
W04B5.5_Cele     -----------------------------------------------VEE-EQPTGRRSS
YDR466W_Scer     -----------------------------------------------DSNGSKDNQNCAS
Pdk1A_Ddis       TTTTNNNNNNNNNNNNNNNNTAAGSNTNTNTNTNINTNINANINNIKTT-EIPKLTRNNS
Pdk1B_Ddis       -----------------------------------------------------KGSRSGS
8643_Tthe        -----------------------------------------------MDD-EDSRTRSST
PDK1_Spur        ---------------------------------------------------KEGQPRAKS
CC1G_15192_Ccin  -----------------------------------------------------STPKTNT
AqueK012_Aque    ------------------------------------------------------DEKASS
PDK1-2_Smoe      ------------------------------------------------SD-AQADDKSCT
PDK1-1_Smoe      -----------------------------------------------VHF-RFTDDKSCT
GK002_Glam       -----------------------------------------------LQN-M-DQQPRCS
                                                                            :

PDK1_Hsap        FVGTAQYVSPELLTEKSAC-KSSDLWALGCIIYQLVAGLPPFRAG---------------
Pk61C_Dmel       FVGTAQYVSPEVLQNGPIT-PAADLWALGCIVYQMIAGLPPFRGS---------------
PDK1_Mmus        FVGTAQYVSPELLTEKSAC-KSSDLWALGCIIYQLVAGLPPFRAG---------------
pdk-1_Cele       FVGTALYVSPEMLADGDVG-PQTDIWGLGCILFQCLAGQPPFRAV---------------
PKH2_Scer        FVGTAEYVSPELLNDSFTD-YRCDIWAFGCILFQMIAGKPPFKAT---------------
PKH1_Scer        FVGTAEYVSPELLNDNYTD-SRCDIWAFGCILYQMLAGKPPFKAA---------------
W04B5.5_Cele     FVGTAFFVTPELLTGSEMS-PSSDLWAFSVTLYLFLTGIYPFNDM---------------
YDR466W_Scer     FVGTAEYVSPELLLYNQCG-YGSDIWALGCMIYQFVQGQPPFRGE---------------
Pdk1A_Ddis       FVGTAEYVSPELISNKETS-TDSDLWALGCIIYQMASGRVPFRGK---------------
Pdk1B_Ddis       FCGTAEYVCPELLTEKSAG-VEADIWSYGCLLYQLVSGKLPFKGF---------------
8643_Tthe        FVGTAEYVSPELLEGEICT-SSADLWALGCIIYRMFVGNTPFVDVND----------ATN
PDK1_Spur        FVGTAQYVSPELLTEKSAT-KSSDLWALGCIVYQLQAGLPPFRAS---------------
CC1G_15192_Ccin  FVGTAAFLSPEVLLRQEANPRGPDLWAVGACLFFYLFGTYPFSAM---------------
AqueK012_Aque    FVGTAEYVSPELLQSKVAY-KSSDLWALGCIIYQFLAGRPPFHAAYVNYTCSPPLFIMCR
PDK1-2_Smoe      FVGTAEYVSPEVLNGHPVT-IGADLWALGCIIYQMLEGRPPFKGG---------------
PDK1-1_Smoe      FVGTAEYVSPEVLNGHPVT-IGADLWALGCIIYQMLEGRPPFKGG---------------
GK002_Glam       IYGTVCYNAPESNRHGLLYMSPQDVWGLGCILYECLTGMPAFMGD---------------
                 : **. :  **            *:*. .  ::    *  .*

PDK1_Hsap        NEYLIFQKIIKLEYDFP---------EKFF-PKARDLVEKLLVLDATKRLGCEE--MEGY
Pk61C_Dmel       NDYVIFKEILDCAVDFP---------QGFD-KDAEDLVRKLLRVDPRDRLGAQDE-FGYY
PDK1_Mmus        NEYLIFQKIIKLEYHFP---------EKFF-PKARDLVEKLLVLDATKRLGCEE--MEGY
pdk-1_Cele       NQYHLLKRIQELDFSFP---------EGFP-EEASEIIAKILVRDPSTRITSQ-------
PKH2_Scer        NEYLTFQKVMKVQYAFT---------PGFP-LIIRDLVKKILVKNLDRRLTI--------
PKH1_Scer        NEYLTFQKVMKIQYAFT---------AGFP-QIVKDLVKKLLVRDPNDRLTI--------
W04B5.5_Cele     SEYLVFRRIQDILYTFS---------EDFPDENAKNLIERLLVKEQKSRLTSQ-------
YDR466W_Scer     NELKTFEKIVALDYPWGPNNRINNSTSPIN-PLVINLVQKILVIEVNERISL--------
Pdk1A_Ddis       TEFLTFQKVSNRELVYP---------INMN-PVIKDLVEKLLVIKPTDRLGSSST-PGGF
Pdk1B_Ddis       NEYQTFLLITKREFSYP---------DNFD-KCCMNLIDQLLDLDPYKRPTI--------
8643_Tthe        NEFKVFNKVKACQYYIP---------DSVP-PEAADLIKNLLKRNPFERIGGGEPGVNDI
PDK1_Spur        NEYMIFQKIIKLEYDFP---------DGFS-QTARDLVSKLLVIDPSKRLGCDE--CGGY
CC1G_15192_Ccin  TDYLIMERIKKLDYKIP---------EGCD-PDAADLIKRLLVHHPQERLGVPP--NSSI
AqueK012_Aque    NEYLCFQKIIKHEYSIP---------DGFP-DNAKDLVENLLVSDPTKRLGCDK--MGGY
PDK1-2_Smoe      SEYLTFQKVLAKDLVIP---------SHFP-SAAKELINKLLNLEPDKRPGAGP---AGY
PDK1-1_Smoe      SEYLTFQKVLAKDLVIP---------SHFP-SAAKELINKLLNLEPDKRPGAGP---AGY
GK002_Glam       VELAIMQAIEKQKVIVP---------KTVS-PDAADLIKRLLTKDPTKRFNG------GW
                  :   :  :                          ::: .:*  .   *

PDK1_Hsap        GPLKAHPFFES---------V-TWEN--LHQQ-------T--PPKL--------------
Pk61C_Dmel       ESIRAHPFFAG---------I-DWQT--LRQQ-------T--PPPI--------------
PDK1_Mmus        GPLKAHPFFET---------I-TWEN--LHQQ-------T--PPKL--------------
pdk-1_Cele       -ELMAHKFFEN---------V-DWVN--IANI-------K--PPVL--------------
PKH2_Scer        SQIKEHHFFKD---------L-NFKDGSVWSK-------T--PPEI--------------
PKH1_Scer        KQIKAHLFFHE---------V-NFEDGSVWDD-------N--PPEI--------------
W04B5.5_Cele     -EIKEHKFFES---------I-DFEH--LEQL-------E--PPRI--------------
YDR466W_Scer     EQIKRHPYFSK---------V-DWND--KIKIWRGIWQSQ--GQSLQQTTLGLPNIPQNI
Pdk1A_Ddis       DNLKAHPFFQD---------F-NWSS--LSNM-------SHPPPPI--------------
Pdk1B_Ddis       SEIKNHEFFSS---------IQDWSS--IPSQ-------T--PPPI--------------
8643_Tthe        NTLKKHPFFKG---------I-NWLT--LSKQ-------A--APKR--------------
PDK1_Spur        PALKAHPFLEG---------V-DWEN--LHEQ-------K--APVL--------------
CC1G_15192_Ccin  DELRQHPFFVGSREDGKSGHI-DWDT--IWTV-------P--APEI--------------
AqueK012_Aque    PPLKAHYFFTD---------V-NWDN--VQNE-------T--PPTL--------------
PDK1-2_Smoe      TALKSHAFFSG---------I-EWLK--LRQS-------A--APGL--------------
PDK1-1_Smoe      AALKSHAFFSG---------I-EWLK--LRQS-------A--APGL--------------
GK002_Glam       RAIKKHPFFTEH-------NV-DFAN--LNNQ-------M--PPFN--------------
                   :  * ::           .  :

PDK1_Hsap        ----------------------------------------------------------TA
Pk61C_Dmel       ----------------------------------------------------------YP
PDK1_Mmus        ----------------------------------------------------------TA
pdk-1_Cele       ----------------------------------------------------------HA
PKH2_Scer        ----------------------------------------------------------KP
PKH1_Scer        ----------------------------------------------------------QP
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     LPTRQLHVIDTPARSIQITKQKRKKPTKISNTTSSIVVWRKRLGISTGKDDLGTVPSTTP
Pdk1A_Ddis       ----------------------------------------------------------QP
Pdk1B_Ddis       ----------------------------------------------------------EQ
8643_Tthe        ----------------------------------------------------------EI
PDK1_Spur        ----------------------------------------------------------KP
CC1G_15192_Ccin  ----------------------------------------------------------KP
AqueK012_Aque    ----------------------------------------------------------LP
PDK1-2_Smoe      ----------------------------------------------------------AP
PDK1-1_Smoe      ----------------------------------------------------------AP
GK002_Glam       -----------------------------------------------------------P


PDK1_Hsap        YLPAM-------------------------------------------------------
Pk61C_Dmel       YLPGV-------------------------------------------------------
PDK1_Mmus        YLPAM-------------------------------------------------------
pdk-1_Cele       YIPAT-------------------------------------------------------
PKH2_Scer        YKINAKSMQAMPSGSDRKLVK----KSVNTLGKSHLVTQRSA-S----SPSVEETTHSTL
PKH1_Scer        YKINAEAMKPLQKVSESDTTV--KMANLQLAGN------GHA-DTPLQAPAATSQEHSVI
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     AVTA--------------------------------------------------PNDT--
Pdk1A_Ddis       PQEKIIFD-------GDELFS----PSL-------------DCTTPR-NNNVDENHQQNS
Pdk1B_Ddis       MVPQSPFP-------SPNSSLRLKKRSLS-VGSPINSSLTYLSQPPI-KP-LNLDNSNID
8643_Tthe        CKQQT-------------------------------------------------------
PDK1_Spur        CTV---------------------------------------------------------
CC1G_15192_Ccin  GPFKS-------------------------------------------------------
AqueK012_Aque    YLPST-------------------------------------------------------
PDK1-2_Smoe      SPSS--------------------------------------------------------
PDK1-1_Smoe      SPSS--------------------------------------------------------
GK002_Glam       SIVFS-------------------------------------------------------


PDK1_Hsap        -----------------------------------------------------SE--D--
Pk61C_Dmel       -----------------------------------------------------SQ--D--
PDK1_Mmus        -----------------------------------------------------SE--D--
pdk-1_Cele       -----------------------------------------------------FG--E--
PKH2_Scer        Y---NNNTHAS-----TESEISIKKRPTDERTAQILENARKGINNRKNQ-PG--KRTP--
PKH1_Scer        SMTAATAAFN--------KDY-------------------------TSQ-PK--L--G--
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     NVLTNTAAHSTANIALP---------------------------------PNSQS--NQV
Pdk1A_Ddis       C----N-------------NN---------------NNNNNNINNINNN-NN---SSS--
Pdk1B_Ddis       Y----N-------------DF---------------ENNQ-IISNNNNNNNN---TTT--
8643_Tthe        -----------------------------------------------------DN--E--
PDK1_Spur        -----------------------------------------------------VD--G--
CC1G_15192_Ccin  -----------------------------------------------------N------
AqueK012_Aque    -----------------------------------------------------TK--G--
PDK1-2_Smoe      -----------------------------------------------------QG--G--
PDK1-1_Smoe      -----------------------------------------------------QG--G--
GK002_Glam       -----------------------------------------------------DL-----


PDK1_Hsap        -------------DE-D--CYGNYDN--------LLSQFGCMQVSSSSSSH-SLS-ASDT
Pk61C_Dmel       -------------E--D--FRSSYTV--PG--D-LEPGLDERQISRLLSAE-LGV-GSSV
PDK1_Mmus        -------------DE-D--CYGNYDN--------LLSQFGFMQVSSSSSSH-SLS-TVET
pdk-1_Cele       -------------P--E--YYSNI-----G--P-VEPGLDDRALFRLM--N-LGN-DASA
PKH2_Scer        -------------SG-A--ASAALAASAAL--TKKT--M---QSYPTSSS--KSSRSSSP
PKH1_Scer        -------------SK-S--STSVRSASNNT--DREVIQK---KVSKNRAS--VSSPSIST
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     KRAQLVAPNRIPPKV-P--VINDNVR--NKSIPRTKPNVP-PLQTSSIPQK-LSTSSASS
Pdk1A_Ddis       -------------NN-I--SNSNSNS--NS--SN------NLNISNG---N-LSTPRSSS
Pdk1B_Ddis       -------------TTTTTTTSANTSG--ST--NN------TLYFTSP---N-VTSPPTSM
8643_Tthe        -------------D--D-----------------DINDF-----------A-PSSPQTPV
PDK1_Spur        -------------E--E--IHSEYY----------VDDFD-LELNPTSLSE-YLK-RIET
CC1G_15192_Ccin  -------------------------------------------------------P----
AqueK012_Aque    -------------EA-G--MHSDYNM---------PSS-----TSEQDFEDRFLQ-CFGL
PDK1-2_Smoe      -------------GN-G--AESDDSE--NS--DWDLAHLG-GRVSRLDVSD-ASSPMSSS
PDK1-1_Smoe      -------------GN-G--AESDDSE--NS--DWDLAHLG-GRVSRLDVSD-ASSPMSSS
GK002_Glam       -------------Q--E---------------------FKHMKV-----------P----


PDK1_Hsap        -GLPQRS---GS------------------------------------------------
Pk61C_Dmel       -AMPVKR---S-------------------------------------------------
PDK1_Mmus        -SLPQRS---GS------------------------------------------------
pdk-1_Cele       -SQPSTP---SN------------------------------------------------
PKH2_Scer        -ATTSRPGTYKRTSS-------------TESKPFAKSPPLSASVLSSKVPMPPYTPPMSP
PKH1_Scer        -TSRGKD---NRSRS---------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     -ALSAPS---TEIRN---------------------------------------------
Pdk1A_Ddis       -SSSSQ------------------------------------------------------
Pdk1B_Ddis       -SSNNT--------PRYINPLPTQSTTTTTTKPAYSSTPS-STILKSTPPPPILSSCSSN
8643_Tthe        -NTTSM------------------------------------------------------
PDK1_Spur        HDRPH-S---PT------------------------------------------------
CC1G_15192_Ccin  ----R-S---SR------------------------------------------------
AqueK012_Aque    G-DPSKT---ES------------------------------------------------
PDK1-2_Smoe      -NEPSSP---SAVLA---------------------------------------------
PDK1-1_Smoe      -NEPSSP---SAVLA---------------------------------------------
GK002_Glam       ----KIM---NS------------------------------------------------


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       ------------------------------------------------------------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       ------VEH---------------------------------------------------
PKH2_Scer        PMTPYDTYQMTPPYTTKQQDYSDTAIAAPKPCISKQNVKNST------------------
PKH1_Scer        ------------------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     -----------------------------------QDLTHTL------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       NLLGKSSNQQYQPFQFHQQQQQQQ--------QQQQRERSSTTTPSPTFLSNHHNQHQKN
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        ------------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       ------------------------------------------------------------


PDK1_Hsap        --------N---IEQYIHDLD---------------------------------------
Pk61C_Dmel       ------------------------------------------------------------
PDK1_Mmus        --------N---IEQYIHDLD---------------------------------------
pdk-1_Cele       --------R---GDPFVSEIA---------------------------------------
PKH2_Scer        -DSPLMNKQDIQWSFYLKNINEHVLRTEKLDF----------------------------
PKH1_Scer        --------SDAFWSRYLQNMDERVLLMKEVA-----------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     -DGR--NS-----------IDIHVLKQDYVFI-YGIPYEHEGPAMSLNSYNKIDNDLITS
Pdk1A_Ddis       ---------------------------------------------Q--------------
Pdk1B_Ddis       LQ------------QSFSSID-------KSSFSTSS------PMSS--------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        --------R---DNK---------------------------------------------
CC1G_15192_Ccin  --------A---ES----------------------------------------------
AqueK012_Aque    --------K---AR----------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       --------D---QA----------------------------------------------


PDK1_Hsap        ----------------------------------------------------SNS----F
Pk61C_Dmel       ----------------------------------------------------TAK----N
PDK1_Mmus        ----------------------------------------------------TNS----F
pdk-1_Cele       ---------------------------------------------------PRAN----S
PKH2_Scer        --------VTTNYDILEKKMLK--------------------------------------
PKH1_Scer        ------------------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     LVAQHKEELKNSESFLQVLTLKKSGMLSYKNTVMEGNDDQENKEHQMANIEDTDL----S
Pdk1A_Ddis       ---------------------------------------------------PT-------
Pdk1B_Ddis       ---------------------------------------------------PR-ILLKPT
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        -----------------------------------------------------------Y
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    -----------------------------------------------------------S
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       -----------------------------------------------------------N


PDK1_Hsap        ELDLQFSEDEKRL--LLEKQAGGNPWHQFV------------------------------
Pk61C_Dmel       SFDL--NDAEKLQ--RLEQQ-KTDKWHVFA------------------------------
PDK1_Mmus        ELDLQFSEDEKRL--LLEKQAGGNPWHQFV------------------------------
pdk-1_Cele       EAEK--NRAARAQ--KLEEQRVKNPFHIFT------------------------------
PKH2_Scer        ----------LNGS-LLDPQLFGKPRHTFL-SQVARSGGEVTGFRNDPTMTAYSKTEDTY
PKH1_Scer        ----------LSTR-NLEDSPVG------L-ENVA-----LD------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     MYDFEFNEL-TRKGFLILEKYKNRIWFIS--L----------------------------
Pdk1A_Ddis       --QRSGSS--GGS--RDGGSS-SNNISKWL-N----------------------------
Pdk1B_Ddis       ELVLMDKDRKRNI--REQQQIDQYQWSRFLLP----------------------------
8643_Tthe        --------------------------RP--------------------------------
PDK1_Spur        VVDL--TPAERKQ--RLERQGKENKWHRFV------------------------------
CC1G_15192_Ccin  ------------------DKAEEELWAKFE------------------------------
AqueK012_Aque    GTEQDIL--DREE--KLKQQASTSTWHPFV------------------------------
PDK1-2_Smoe      ----------SAA--RLLDENVHEPWQKFL-F----------------------------
PDK1-1_Smoe      ----------SAA--RLLDENVHEPWQKFL-F----------------------------
GK002_Glam       MLNL--ID-------TSEYRSKDSPLRRFL-I----------------------------


PDK1_Hsap        -----------------------------------------------------ENNLILK
Pk61C_Dmel       -----------------------------------------------------DGEVILK
PDK1_Mmus        -----------------------------------------------------ENNLILK
pdk-1_Cele       -----------------------------------------------------NNSLILK
PKH2_Scer        YSKNIIDLQLLEDDYRIEGGDLSELLTNRSGEGYKCNQNSSPMKDDDKSESNNKGSS-VF
PKH1_Scer        -YKNPLDI----------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     -----------------------------------------------------PSYSTLS
Pdk1A_Ddis       -----------------------------------------------------NGENVIY
Pdk1B_Ddis       -----------------------------------------------------NDEIILA
8643_Tthe        ----------------------------------------------------------LI
PDK1_Spur        -----------------------------------------------------EGNLILK
CC1G_15192_Ccin  -----------------------------------------------------EIHLIED
AqueK012_Aque    -----------------------------------------------------NGELIIK
PDK1-2_Smoe      -----------------------------------------------------EGETILA
PDK1-1_Smoe      -----------------------------------------------------EGETILA
GK002_Glam       -----------------------------------------------------PGENIIY


PDK1_Hsap        MGPVDK---------------RK-----------GLFARRRQLLLTE-GPHLYYV-----
Pk61C_Dmel       KGFVNK---------------RK-----------GLFARKRMLLLTT-GPRLIYI-----
PDK1_Mmus        MGPVDK---------------RK-----------GLFARRRQLLLTE-GPHLYYV-----
pdk-1_Cele       QGYLEK---------------KR-----------GLFARRRMFLLTE-GPHLLYI-----
PKH2_Scer        SGKIKKLFHPTSAAETLSSSDEK-----------TKYY-KRTIVMTSFGRFLVFAKRRQP
PKH1_Scer        -EPP---------------TDSA-----------GKFY-KKMFLITNLGRALVFVKRRSL
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     KIPFNA---------------VKSSTINNNENWVDCFFRARQLLE-E-KQILDKI-----
Pdk1A_Ddis       QGLVWK---------------RK-----------GFSIKKRQLILTD-TPRLIYI-----
Pdk1B_Ddis       CGITEK---------------RS-----------GLITKKRQLIITD-TPRIFYV-----
8643_Tthe        TGRVLK---------------KVA----------WLIYKPRQLILQEEPPKLVYY-----
PDK1_Spur        NGWVDK---------------RK-----------GLFARRRMLLLTE-GPHLYYV-----
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    TGLVDK---------------RK-----------GMFSKRRQLILTD-APRLYYV-----
PDK1-2_Smoe      SSRVRK---------------FR-----------KLSVKKRQLILTD-RPRLFYV-----
PDK1-1_Smoe      SSRVRK---------------FR-----------KLSVKKRQLILTD-RPRLFYV-----
GK002_Glam       SIDVVK---------------RRV----------LRLPKQRRFVLTD-FPRLFYI-----


PDK1_Hsap        D-----------------------------------------------------------
Pk61C_Dmel       D-----------------------------------------------------------
PDK1_Mmus        D-----------------------------------------------------------
pdk-1_Cele       D-----------------------------------------------------------
PKH2_Scer        N-----------------------------------------------------------
PKH1_Scer        ------------------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     SNVSFDSKASSEPSSPPPISRKERPLSIGNNVTTLSYTAKNGSQNNAPQNDNVGEEKPFR
Pdk1A_Ddis       D-----------------------------------------------------------
Pdk1B_Ddis       D-----------------------------------------------------------
8643_Tthe        D-----------------------------------------------------------
PDK1_Spur        D-----------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    D-----------------------------------------------------------
PDK1-2_Smoe      H-----------------------------------------------------------
PDK1-1_Smoe      H-----------------------------------------------------------
GK002_Glam       D-----------------------------------------------------------


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       ------------------------------------------------------------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       ------------------------------------------------------------
PKH2_Scer        ------------------------------------------------------------
PKH1_Scer        ------------------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     IPSSTKDRPGANSTPSSRHPRVLSSNNAGETPKKMNGRLPNSAPSTNTYTNGSVPAFNHR
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ------------------------------------------------------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        ------------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       ------------------------------------------------------------


PDK1_Hsap        ------------------------PV-------------------NKVLKGEIPWSQ-EL
Pk61C_Dmel       ------------------------PV-------------------QMIKKGEIPWSP-DL
PDK1_Mmus        ------------------------PV-------------------NKVLKGEIPWSQ-EL
pdk-1_Cele       ------------------------VP-------------------NLVLKGEVPWTP-CM
PKH2_Scer        ------------------------PV-------------------T-NLKYELEYDI-NL
PKH1_Scer        -----------------------------------------------SMWEEQEFEL-QF
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     PSTNVGNNKHNILTSKKQGSSVFSPSSSTTKPQIKTTGYRQPTPSPPLPQMEFPTTR-EK
Pdk1A_Ddis       ------------------------PK-------------------KMELKGEIPWSD-SI
Pdk1B_Ddis       ------------------------PV-------------------KMTQKGEITVDG-SL
8643_Tthe        ------------------------PM-------------------TNVKKGEIPLSK-NV
PDK1_Spur        ------------------------PE-------------------NMVLKGEIPWSP-QL
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------PV-------------------AMVLKGEIPWSS-NI
PDK1-2_Smoe      ------------------------PI-------------------KLVFKGEVPWSR-DI
PDK1-1_Smoe      ------------------------PI-------------------KLVFKGEVPWSR-DI
GK002_Glam       ------------------------VS-------------------TMVQKGEIDMTSTNL


PDK1_Hsap        RP----------------------------------------------------------
Pk61C_Dmel       RA----------------------------------------------------------
PDK1_Mmus        RP----------------------------------------------------------
pdk-1_Cele       QV----------------------------------------------------------
PKH2_Scer        RQQG--------------------------------------------------------
PKH1_Scer        ELEL--------------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     YS----------------------------------------------------------
Pdk1A_Ddis       KP----------------------------------------------------------
Pdk1B_Ddis       SA----------------------------------------------------------
8643_Tthe        KI----------------------------------------------------------
PDK1_Spur        KV----------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    KI----------------------------------------------------------
PDK1-2_Smoe      YV----------------------------------------------------------
PDK1-1_Smoe      YV----------------------------------------------------------
GK002_Glam       KITRIGERTIEFTLGQNCFTAEVLTKDLCDLWLRYMTMYSVNGKTAMANIMANRANLVKV


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       ------------------------------------------------------------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       ------------------------------------------------------------
PKH2_Scer        ------------TKIK--------------------------------ELI---------
PKH1_Scer        ------------NDVEKIR----------------------------FISD---------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ------------------------------------------------------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        ------------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       SDQDMRCEMCKGRLFK-NGFCNTCGNVAQVSNNGSSTIQYILKMDPRWLPVSEKEIRLHS


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       ------------------------------------------------------------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       ------------------------------------------------------------
PKH2_Scer        -------I----------------------------------------------------
PKH1_Scer        -------Q----------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ------------------------------------------------------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        ------------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       RLALISGIQPEMDNIEAMSRYETRSSVQKAIDRLKKTQEDVVVYKNRQDQPLDGSTTLPD


PDK1_Hsap        ----------------------------EAKN-----FKTFFVHT---------------
Pk61C_Dmel       ----------------------------EYKN-----FKIFFVHT---------------
PDK1_Mmus        ----------------------------EAKN-----FKTFFVHT---------------
pdk-1_Cele       ----------------------------ELKN-----SGTFFIHT---------------
PKH2_Scer        --------------------------PLEMGT-----NHIVVIQT---------------
PKH1_Scer        --------------------------VLEIDG-----SRTIFIGC---------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ----------------------------APSNMVISSSRYEVLHT---------------
Pdk1A_Ddis       ----------------------------KLKS-----NNNFVIKT---------------
Pdk1B_Ddis       ----------------------------QQKS-----SKHFIINS---------------
8643_Tthe        ----------------------------ELQD-----KSRFTIVG---------------
PDK1_Spur        ----------------------------EAKN-----FKTYFVHT---------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ----------------------------EQKN-----FKIFFVHT---------------
PDK1-2_Smoe      ----------------------------RVEN-----DLKFCICT---------------
PDK1-1_Smoe      ----------------------------RVEN-----DLKFCICT---------------
GK002_Glam       QQSAISGPTVELTTQEAVQASSTLCATPELKE-----LQSGFVQSGQISQLSGTALLLNP


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       ------------------------------------------------------------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       ------------------------------------------------------------
PKH2_Scer        ------------------------------------------------------------
PKH1_Scer        ------------------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ------------------------------------------------------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        ------------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       PLATKPKPASEKDSAIYGTQFPNLPNMRRSSAECCLPSSANVDDEELQSDMYKDQARMSG


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       ------------------------------------------------------------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       ------------------------------------------------------------
PKH2_Scer        ------------------------------------------------------------
PKH1_Scer        ------------------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ------------------------------------------------------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        ------------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       ASTLSSITNRQSMSVQVISKQEKDLFEFFHANDSLINLEESGHVLPSSEQAARVSVDGKS


PDK1_Hsap        ----------------------------------------------------------PN
Pk61C_Dmel       ----------------------------------------------------------PN
PDK1_Mmus        ----------------------------------------------------------PN
pdk-1_Cele       ----------------------------------------------------------PN
PKH2_Scer        ----------------------------------------------------------PY
PKH1_Scer        ----------------------------------------------------------KE
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ----------------------------------------------------------LN
Pdk1A_Ddis       ----------------------------------------------------------PK
Pdk1B_Ddis       ----------------------------------------------------------KG
8643_Tthe        ----------------------------------------------------------PK
PDK1_Spur        ----------------------------------------------------------PN
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ----------------------------------------------------------PN
PDK1-2_Smoe      ----------------------------------------------------------PK
PDK1-1_Smoe      ----------------------------------------------------------PK
GK002_Glam       YQDGGIMDGINQAHLDSIVQQVTLTSPLHTERNSASLITPPLNSCQYKYETPVYPQSSPN


PDK1_Hsap        RT----------------YYLM--------------------------------------
Pk61C_Dmel       RT----------------YYLD--------------------------------------
PDK1_Mmus        RT----------------YYLM--------------------------------------
pdk-1_Cele       RV----------------YYLF--------------------------------------
PKH2_Scer        KS----------------FLLS--------------------------------------
PKH1_Scer        RA----------------VLMK--------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     NS----------------QTNF--------------------------------------
Pdk1A_Ddis       RK----------------YLLE--------------------------------------
Pdk1B_Ddis       RS----------------RHFY--------------------------------------
8643_Tthe        KK----------------YFFK--------------------------------------
PDK1_Spur        RT----------------YYLI--------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    RT----------------YYLE--------------------------------------
PDK1-2_Smoe      RT----------------YNLE--------------------------------------
PDK1-1_Smoe      RT----------------YNLE--------------------------------------
GK002_Glam       KAIPQKQSDLPTDIPGLLTYMDETPGHSVTPAVAPSGHASAVINKRDTLNSLQSMILGEF


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       ------------------------------------------------------------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       ------------------------------------------------------------
PKH2_Scer        ------------------------------------------------------------
PKH1_Scer        --------------------------------------LWKLIHN-GMTAKPKVV-----
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ------------------------------------------------------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        ------------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       PELPTNVANQSSHIRITTASTQAILGSHSYSVRCLLAKIYAVSSAAELLPYPTLPLPRIL


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       ------------------------------------------------------------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       ------------------------------------------------------------
PKH2_Scer        ------------------------------------------------------------
PKH1_Scer        ------------------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ------------------------------------------------------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        ------------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       GYCGDRLLLQYRENIGVIGKFLTILYVLNNKQAILPPLGTTIVDKVEPHCICICQNERRV


PDK1_Hsap        ---D--------------------------------------------------------
Pk61C_Dmel       ---D--------------------------------------------------------
PDK1_Mmus        ---D--------------------------------------------------------
pdk-1_Cele       ---D--------------------------------------------------------
PKH2_Scer        ---T--------------------------------------------------------
PKH1_Scer        ---S--------------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ---D--------------------------------------------------------
Pdk1A_Ddis       ---D--------------------------------------------------------
Pdk1B_Ddis       ---D--------------------------------------------------------
8643_Tthe        ---E--------------------------------------------------------
PDK1_Spur        ---D--------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ---D--------------------------------------------------------
PDK1-2_Smoe      ---D--------------------------------------------------------
PDK1-1_Smoe      ---D--------------------------------------------------------
GK002_Glam       KLSDNIDTNYDVTIRHASPCYTCGGDVFKELPTGEIINDALLASLKSQQTSVTQIPTIVF


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       ------------------------------------------------------------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       ------------------------------------------------------------
PKH2_Scer        ------------------------------------------------------------
PKH1_Scer        ------------------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ------------------------------------------------------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        ------------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       PQGLSAANEKTTSKAPEVSGSVLVKRATMSNKKVSSVQLDDEIPLVSRDLNEEHSTNSYM


PDK1_Hsap        --------------------------------PS--------------------------
Pk61C_Dmel       --------------------------------PE--------------------------
PDK1_Mmus        --------------------------------PS--------------------------
pdk-1_Cele       --------------------------------LE--------------------------
PKH2_Scer        --------------------------------DK--------------------------
PKH1_Scer        --------------------------------PK--------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     --------------------------------RE--------------------------
Pdk1A_Ddis       --------------------------------VA--------------------------
Pdk1B_Ddis       --------------------------------LD--------------------------
8643_Tthe        --------------------------------LD--------------------------
PDK1_Spur        --------------------------------PE--------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    --------------------------------PT--------------------------
PDK1-2_Smoe      --------------------------------TK--------------------------
PDK1-1_Smoe      --------------------------------TK--------------------------
GK002_Glam       AVFDKRRTSNTVCIQELDTESEECFETYKHFDTEPSVETAVPLSAGLKFYFHANGNTPVA


PDK1_Hsap        ------------------------------------------------------GNAHKW
Pk61C_Dmel       ------------------------------------------------------GYAIHW
PDK1_Mmus        ------------------------------------------------------GNAHKW
pdk-1_Cele       ------------------------------------------------------KKADEW
PKH2_Scer        ------------------------------------------------------KTTSKL
PKH1_Scer        ------------------------------------------------------SDHKMF
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ---------------------IAS------------------------------RGASAA
Pdk1A_Ddis       ------------------------------------------------------HNPQKW
Pdk1B_Ddis       ------------------------------------------------------GQSKLW
8643_Tthe        ------------------------------------------------------HPANIW
PDK1_Spur        ------------------------------------------------------SDAVEW
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------GSAKKW
PDK1-2_Smoe      ------------------------------------------------------GQARVW
PDK1-1_Smoe      ------------------------------------------------------GQARVW
GK002_Glam       LIPIAELSWLNIGASARYRKAIKEKVAEALTPLCCSHQRKPEVSLPGIMSIKQFQQKDKW


PDK1_Hsap        CRKIQEV----------WRQ-------------RY-----------Q-------------
Pk61C_Dmel       SEAIENM----------RKL-------------AY-----------G-------------
PDK1_Mmus        CRKIQEV----------WRQ-------------QY-----------Q-------------
pdk-1_Cele       CKAINDV----------RKR-------------YS-----------V-------------
PKH2_Scer        FTVLKKI----------LNS-------------NTNKIEKELLQRNQKVIERRTSSSGRA
PKH1_Scer        D-----------------------------------------------------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     FRSLQ-------------------------------------------------------
Pdk1A_Ddis       VDSIKSV----------ILS----------------------------------------
Pdk1B_Ddis       VDLINEL----------NM-----------------------------------------
8643_Tthe        VEKVSKL----------IKD-------------K--------------------------
PDK1_Spur        CQAIKEM----------YRH-------------TY-------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    VETLNKS----------LVL----------------------------------------
PDK1-2_Smoe      KESIE-------------------------------------------------------
PDK1-1_Smoe      KESIE-------------------------------------------------------
GK002_Glam       CKYLGANGSAFELTEEIYKVGKLQDLRFLLEMNTYH-------KQVSF------------


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       ----DPSSTSAVSCSSGSSNSLAVISNSSAASSSNSPTVKRSSPV-----------NAPQ
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       ----TIEKTFNSAMRDGTFGSIYGKKKS------------RKEMMREQKA-----LRRKQ
PKH2_Scer        IPKDLPTSKSPSPKPRTHSQSPSISKHNSFSESINSAKSNRSS------RIFETFINAKE
PKH1_Scer        -----------------------------------------------------KFILQKR
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ------------------------------------------------------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        ------------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       ----DVTIQYDE-SSDGYFNALYLDE------------CMRSSAVSATTA----------


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       A--------ST-------------------------------------------------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       E-----------------------------------------------------------
PKH2_Scer        QNSKK--HAAPVPLTSKLVNGLPKRQV---------------------------------
PKH1_Scer        QNTKKKNQAPPVPQSNRLINGLPDRCILKTPEEGALHTKRPTSLQT---RSS--------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ------------------------------------------------------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        ------------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       -----------------------------------------YTVEDLGTSTGTSIHNHNK


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       --ASDNRTL--------------------------------------------------G
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       --KEEKKAL--------------------------------------------------K
PKH2_Scer        ---TVGLGL--------------------------------------------------N
PKH1_Scer        --SNYSKLL--------------------------------------------------A
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ------------------------------------------------------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        ------------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       PDTVYQHMVEDYTQSSFKLANRQPYIHYCRRCVCSECISKIEQKDCFIKLEAVEQKSAFI


PDK1_Hsap        ------------------------------------------------------------
Pk61C_Dmel       S---------------------------------------------T-------------
PDK1_Mmus        ------------------------------------------------------------
pdk-1_Cele       A---------------------------------------------EQV-----------
PKH2_Scer        ----------------------------------------------TG------------
PKH1_Scer        ----------------------------------------------RS------------
W04B5.5_Cele     ------------------------------------------------------------
YDR466W_Scer     ------------------------------------------------------------
Pdk1A_Ddis       ------------------------------------------------------------
Pdk1B_Ddis       ------------------------------------------------------------
8643_Tthe        ------------------------------------------------------------
PDK1_Spur        ------------------------------------------------------------
CC1G_15192_Ccin  ------------------------------------------------------------
AqueK012_Aque    ------------------------------------------------------------
PDK1-2_Smoe      ------------------------------------------------------------
PDK1-1_Smoe      ------------------------------------------------------------
GK002_Glam       ASEFGKDEYSFELFKSWVSRRFPFQFREGNFPLRHRCRYEQCKRYVESIAPCGDVNLRLP


PDK1_Hsap        --------------------------SHPDAAVQ
Pk61C_Dmel       ----------------RT-----GTSPSKKTASK
PDK1_Mmus        --------------------------SNPDAAVQ
pdk-1_Cele       ----------------SK-----KLSMQMDKKSP
PKH2_Scer        ----------------TN-----FKNSSAKSKRS
PKH1_Scer        ----------------TQ-----MRKNMTRTDEK
W04B5.5_Cele     ---------------------------------Y
YDR466W_Scer     ----------------------------KSKKKK
Pdk1A_Ddis       -----------------------------SGSSN
Pdk1B_Ddis       ------------------------------LSFK
8643_Tthe        ----------------------------FEDLKL
PDK1_Spur        ------------------------------QKSI
CC1G_15192_Ccin  ------------------------------EGRI
AqueK012_Aque    ----------------------------YKSQNK
PDK1-2_Smoe      ----------------------------KLVNAK
PDK1-1_Smoe      ----------------------------KLVNAK
GK002_Glam       FVTMARPADAEVMEVGTQIPTSAELDEYWVDFAT