VACAMKL_Hsap MPFGCVTLG---------------------------------------------------
PRR1_Scer MDEYSSIYSQPKTPRL--------------------------------------------
MEK1_Scer MRPLYSCNLATK------------------------------------------------
VACAMKL_Mmus MPFGCVTLG---------------------------------------------------
YKL171W_Scer MFTSQRQLRQNGSP--------MSSSRSSQHSSGTASPISDSPASNRSYGRDLRGLMGID
YMR291W_Scer MTTASSSASQLQQR----------------------------------------------
5683_Tthe MGNCTHKPN-INK-----------------------------------------------
CC1G_13697_Ccin MS----------------------------------------------------------
CC1G_07362_Ccin MLQYPVQVPSLSLS--------SSAKLASK-----------------PSKDNIPYLLSND
CC1G_09141_Ccin MSTSSASTRSTSSS--------FSSTFSDVDDP-MFSPPSSPPASSKTHAFFASSFAASP
CC1G_07180_Ccin MEHFESNYVSIGRIQPQ-----AWSTFANF-----------------FPHGDAPHLATSP
AqueK053_Aque MAGHLHSPR-NR------------------------------------------------
GK018_Glam MPDGAVVTGSVRHRKIQAIRAIKAMDL---------------TASNA----TIEELAKNI
*
VACAMKL_Hsap -----------------------------------------------------DK-----
PRR1_Scer ------------------------------------------------------------
MEK1_Scer ------------------------------------------------------------
VACAMKL_Mmus -----------------------------------------------------DK-----
YKL171W_Scer IPANEP-AFNRANSS----------DTIYFRPK---KIYKMEHEHP-SRSTLVQL-----
YMR291W_Scer ------------------------------------------------------------
5683_Tthe ------------------------------------------------------------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin PPR-QPQP------LSSLRFQKDPYAARPVGPN---RL------PA-PIVPLSISTN---
CC1G_09141_Ccin --------------------------------------------PP-PRPPLSLK-----
CC1G_07180_Ccin L-------------------------------------------------PVNESHG---
AqueK053_Aque ------------------------------------------------------------
GK018_Glam AKR-FPNL------WTEEKIVQLML------DARENKL------PETEEVPTSLTSTPVQ
VACAMKL_Hsap ----------KNYNQPSEVT----------------------------------------
PRR1_Scer ----------KQEGFPDSIGDQ----------HEKALIDENGEEDKKMASTEGTTGD---
MEK1_Scer ----------DDIEMAGGVAPA--------------------------------------
VACAMKL_Mmus ----------KNYNQPSEVT----------------------------------------
YKL171W_Scer ----------QTRSQPDDVASSQVNPEGGTDDLEL--------------------GDPCG
YMR291W_Scer -------L-------PE-------------------------------------------
5683_Tthe ----------KNLKLQTK---YQ--------------VNNKI------------------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin ------LVPSPSASSPSTAS----------AK----------------------------
CC1G_09141_Ccin ----------KSDNKPTAVKNR----------DDN--------------------GTNPP
CC1G_07180_Ccin ------HFP-----SPQKVGDE----------DVL--------------------GD---
AqueK053_Aque ----------PR------------------------------------------------
GK018_Glam SGQLDQKTPQASRSSPSKI-----------------------------------------
VACAMKL_Hsap ------------------------------------------------------------
PRR1_Scer ------------------------------------------------------------
MEK1_Scer ------------------------------------------------------------
VACAMKL_Mmus ------------------------------------------------------------
YKL171W_Scer NQSLYTIGAEYVPDLDFTKLV-------------------------------------NE
YMR291W_Scer ------------------------------------------------------------
5683_Tthe ------------------------------------------------------------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin ------------------------------------------------------------
CC1G_09141_Ccin PA-------------ASPGLFSSAKTSRFNVSRIFPSRYARSRRDSAEQQDVQNAFSSNA
CC1G_07180_Ccin ------------------------------------------------------------
AqueK053_Aque ------------------------------------------------------------
GK018_Glam ------------------------------------------------------------
VACAMKL_Hsap ------------------------------------------------------------
PRR1_Scer -------------------------SRSTPLTVSIPT--------------------FEN
MEK1_Scer -----------------------------HLE----------------------------
VACAMKL_Mmus ------------------------------------------------------------
YKL171W_Scer WQKSTEDLYE-------------FRSSATP------QVQIKDSGKGNYELWSSPDAILTQ
YMR291W_Scer ------------------------------------------------------------
5683_Tthe --KS-------------------------------------------------DSDIFED
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin ------------------------------------------------------------
CC1G_09141_Ccin LRRKPDFLFIDVDGDADPNEIHHIDHRETP------F-----------------------
CC1G_07180_Ccin ------------------------------------------------------------
AqueK053_Aque ------------------------------------------------------------
GK018_Glam ---------------------------------------------------------FHQ
VACAMKL_Hsap ------------------------------------------------------------
PRR1_Scer VQA-------LPTPMTY-TPLSPGNLSMSPID----QS----------------------
MEK1_Scer ---------------------------------V-NVGGYNT--EQTIPIVK--------
VACAMKL_Mmus ------------------------------------------------------------
YKL171W_Scer NKLRRDSFSQ------------ENSDSLSPEDSI-LSRNLHSKV-KPIPLPRNS------
YMR291W_Scer --------------------------------------------EKPWPQLSG-------
5683_Tthe VTPDRK-----PQNLTI-IPKK-SQFKLKPVK-----Q----NLEEPLPSNI--------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin ----------------------------HPRSPYISSRQLSA---SPV--P---------
CC1G_09141_Ccin ----KDVFLSLPTAPSY-HDRAGSDSSLSPPSSI-SSSSSHAEI-R-LPTPPP-------
CC1G_07180_Ccin ------------------------------------------------------------
AqueK053_Aque ------------------------------------------------------------
GK018_Glam ETAQKAPF-----TKTAQLPVLGGASAANPV---YSSGSFQANQTPPPPHPADSHDRLYR
VACAMKL_Hsap ------------------------------------------------------------
PRR1_Scer -------------------------------SLNIPKRRSHARL--LDDMLSVTQPNQRV
MEK1_Scer -----------------------------------HQLVKVGR---N-DKECQLVLTNPS
VACAMKL_Mmus ------------------------------------------------------------
YKL171W_Scer -----------------------QQIFTPLSNLEAERRSSYTTS--S-NNNSITQNNKFS
YMR291W_Scer ------------------------------------------------------------
5683_Tthe -----------------------------------------T-K----------------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin ------------------------------------------------------------
CC1G_09141_Ccin ------------------------------------PPP-LLTA--S-SNAS---DNEFT
CC1G_07180_Ccin ------------------------------SELDKEQRVSAAF---I-DADTIIEDHSPS
AqueK053_Aque ------------------------------------------------------------
GK018_Glam NHISLGLELAGLERKYLMLRYDANRMFAPPRALQKQTSAVYSVAHYE-KQHALKQLKE-R
VACAMKL_Hsap ------------------------------------------------------------
PRR1_Scer VSELIA---PA------NLSPQR-------------------VVSLP---------TVTE
MEK1_Scer ISSV-H---CVFWCVFFDE----DSIPMFYVKDCSLNGTY-LN---GLLLKRDKTYLLKH
VACAMKL_Mmus ------------------------------------------------------------
YKL171W_Scer FAKL-K-----------YSLPTQSSAVPASFDSNASSLNFLPTTTLS---------TLSE
YMR291W_Scer ------------------------------------------------------------
5683_Tthe ------------------------------------------------------------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin ---F-------------RQQPS-GPAPPSALSQCASSGSYPIE-----------------
CC1G_09141_Ccin --P--R---PA------DLEPSI------------AAVQPQELSPLS---------PLSE
CC1G_07180_Ccin ISPV-R---PS------VSQPTTLASSPAALFLSA-------------------------
AqueK053_Aque ------------------------------------------------------------
GK018_Glam IADL-EGRLKG------RLSPKDRATYTAQY----NAA---AIECRS---------LLTE
VACAMKL_Hsap ------------------------------------------------------------
PRR1_Scer EAL----------------------------------V---------------------N
MEK1_Scer C------------D-----------VIELSQGSEEND---------------------IK
VACAMKL_Mmus ------------------------------------------------------------
YKL171W_Scer -------LQISPNDMMDLIQKLPRNFLNLPYTQRKKVIIEHAPSHDYKAMMSLVKKFMLT
YMR291W_Scer ------------------------------------------------------------
5683_Tthe --------------------------------S---------------------------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin -------DVLTPGDIVGEGLVLQNEVLRLVGS----------------------------
CC1G_09141_Ccin DNSIPADTELHPGDVIA-------------------------------------------
CC1G_07180_Ccin ------------------------------------------------------------
AqueK053_Aque ------------------------------------------------------------
GK018_Glam L------------DV-----------INLQA-EEDGV---------------------IR
VACAMKL_Hsap ------------------------------------------------------------
PRR1_Scer D---------SVDSDNYTKEPYFPESSSSTE-----KCDDD------------IFQ----
MEK1_Scer KTRLVFMI-----------------NDDLQSS----LD--PK------------------
VACAMKL_Mmus ------------------------------------------------------------
YKL171W_Scer SSRSNFSLAGFAN--NASVSQATANDDNINSRNTPNN----SNDTYVNTRPLQRSRHGSI
YMR291W_Scer ------------------------SN----------------------------------
5683_Tthe -------------SE-----------------NQMEK-----------------------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin ------------------------------------T-----------------------
CC1G_09141_Ccin ------------------------------------------------------------
CC1G_07180_Ccin ----------FMG--SK-------------------PE--PE------------------
AqueK053_Aque ------------------------------------T-----------------------
GK018_Glam RQVSTYCLSNYYN--NESLPVLFPMNADVTVRN----Y--Q------------TVK----
VACAMKL_Hsap ------------------------------------------DRY-DLGQVIKTEEFCEI
PRR1_Scer ------------------------------GFLLDHW--DRPLLW-KKVRPIGSGNFSTV
MEK1_Scer -------------------------------LLDQMGFLREVDQWEITNRIVGNGTFGHV
VACAMKL_Mmus ------------------------------------------DRY-DLGQVIKTEEFCEI
YKL171W_Scer ASQFLSSFSPSMTSIAKMNSNPLSGSAGGSARPDDKG--MEILGH-RLGKIIGFGAWGII
YMR291W_Scer --------------------------------ADAQT---FKCKYVTNHNSLGDGNFSVV
5683_Tthe ------------------------------TTSSRQN---IYDNY-KMIKLIGKGSFGKV
CC1G_13697_Ccin -------------------------------------------------QCLGTGSFATV
CC1G_07362_Ccin ------------------------------NESDAAA---PAKEF-EVVRVLGTGSYAVV
CC1G_09141_Ccin ------------------------------DSSFASA---TSPSL-RLLRPLGQGAFSAV
CC1G_07180_Ccin ------------------------------PLEDDEG--QKVGSY-TLGKVVGFGAFSTI
AqueK053_Aque ------------------------------RIEDDSG---IEVDY-SLGEMLGKGAFGVV
GK018_Glam ------------------------------LPPVAST---VRPRY-ILMKKLGSGGFSTV
. : : :
VACAMKL_Hsap FRA--KDKT---------------------------------------------------
PRR1_Scer LLYELMDQSNPK------------------------------------------------
MEK1_Scer LIT--HNSKERDE-----------------------------------------------
VACAMKL_Mmus FRA--KDKT---------------------------------------------------
YKL171W_Scer REC--FDIE---------------------------------------------------
YMR291W_Scer KEC--MNIH---------------------------------------------------
5683_Tthe RLA--TNVN---------------------------------------------------
CC1G_13697_Ccin HLA--FDPT---------------------------------------------------
CC1G_07362_Ccin YLV--REILSRPP-----------------------------------------------
CC1G_09141_Ccin WLA--EDLSSIPLVLSSKRSVRDLKRQASLQSKGSVSRKSSLKSPTSSRGVSRNSSMKRF
CC1G_07180_Ccin RTG--VSE----------------------------------------------------
AqueK053_Aque WEA--TSVN---------------------------------------------------
GK018_Glam YKA--MDLS---------------------------------------------------
.
VACAMKL_Hsap ------------------------------------------------------------
PRR1_Scer ------------------------------------------------------------
MEK1_Scer ------------------------------------------------------------
VACAMKL_Mmus ------------------------------------------------------------
YKL171W_Scer ------------------------------------------------------------
YMR291W_Scer ------------------------------------------------------------
5683_Tthe ------------------------------------------------------------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin -----------------------------PSEDGHMTTIGSMD-----------------
CC1G_09141_Ccin MARVTGTQPSVDSLLLDGHVHHEGRETTWTSPDGHLHPMPPSSMHPSPSPSSSISSLPSP
CC1G_07180_Ccin ------------------------------------------------------------
AqueK053_Aque ------------------------------------------------------------
GK018_Glam ------------------------------------------------------------
VACAMKL_Hsap ------------------------TGKLHTCKKFQKRDG----------------RK-VR
PRR1_Scer -------------------------LKQVAVKRLKYPEELSNVEQINTSLRYKETLSRLE
MEK1_Scer --------------------DVCYHPENYAVKIIKLK----------------------P
VACAMKL_Mmus ------------------------TGKLHTCKKFQKRDG----------------RK-VR
YKL171W_Scer ------------------------TGVGRVIKIVKFKGH----------------QN-IK
YMR291W_Scer ------------------------TKDLYAMKLIKKQTVK-----------------NKI
5683_Tthe -------------------------GKEFAVKSILKADA----------------GE-RY
CC1G_13697_Ccin ------------------------HHKQVACKSIRTRRE----------------N-EVR
CC1G_07362_Ccin ---------------MDGT-PQLEYGREYAIKLLSKANL----------------DEEAL
CC1G_09141_Ccin EVGLGASLSRQSSTSTRRSATSRAEARVVAVKLTPRRPEPNS-P---------LTEERTR
CC1G_07180_Ccin ------------------------SGSTVAVKIVRRADLVRT-G----------HAPEER
AqueK053_Aque ------------------------SKEKFAIKMVHKDKP----------------GSVSI
GK018_Glam ------------------------TAQIVALKISRKETSLEGDEH--------IAETKRW
. *
VACAMKL_Hsap KAAKNEIGILKMV-------------------KHPNILQLVD----------------VF
PRR1_Scer NSLTRELQVLKSL-------------------NHPCIVKLLGI--NN----------PIF
MEK1_Scer NKFDKEARILLRL-------------------DHPNIIKVYH----------------TF
VACAMKL_Mmus KAAKNEIGILKMV-------------------KHPNILQLVD----------------VF
YKL171W_Scer KHVLREVAIWRTL-------------------KHNRILPLLD----------------WK
YMR291W_Scer QLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFD----------------YF
5683_Tthe YLLRRELDIMKKV-------------------DHPNLVKFYE----------------TY
CC1G_13697_Ccin -QVLKEVRILMTL-------------------KHPNINEIYD----------------TE
CC1G_07362_Ccin AAQMTEVTIHQSLP------------------LHPNIVTLHR----------------TL
CC1G_09141_Ccin VGFIREVEVLRHI-------------------SHPNITPLLA----------------HF
CC1G_07180_Ccin KRLQHEASIWSSL-------------------SHEHILPLFS----------------AL
AqueK053_Aque QLLEREIQVLNHV-------------------DHPHIIKLVE----------------VF
GK018_Glam LFLNREAAIYHHL-------------------KHPNIVQLNSDPIFVNSTTGRIVLNPAY
* : : * : .
VACAMKL_Hsap VTRK---------------EYFIFLELATGREVFDWILDQGYY-----------------
PRR1_Scer VTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNG----R-------------
MEK1_Scer CDRNN--------------HLYIFQDLIPGGDLFSYLAKGDCLT--S-------------
VACAMKL_Mmus VTRK---------------EYFIFLELATGREVFDWILDQGYY-----------------
YKL171W_Scer LDDNY--------------AMYCLTERINDGTLYDLVISWDEFKRSK-IP----------
YMR291W_Scer ETAD---------------NIVLITQLCQKGDLYEKIVEN----QCL-------------
5683_Tthe HDDK---------------YLHIVMEFVQGKELSQYCQERFEVN-RK-------------
CC1G_13697_Ccin EDNG---------------FIHIFLQLCTGGDLFTYISTVNLKADRP--G----------
CC1G_07362_Ccin ETPS---------------FLLLLLEYVPGEDLFYFLEQARDHYEPQPSDFVMYNSRTPP
CC1G_09141_Ccin STPT---------------YHVLVLPYLKGGDLLSLVNNDAVWGR---------------
CC1G_07180_Ccin HTSY---------------ADYFVTIYCPAGSLYDILKRDGRPAL---------------
AqueK053_Aque ETPK---------------KVFMVLELCRGGELSDILKEKKSF-----------------
GK018_Glam EPYN---------------EIALSMELCEGGDLHDFLALLCRSDKQA-------------
:
VACAMKL_Hsap --------------SER---DTSNVVRQVLEAVAYLHSL--KIVHRNLKLENLVYYNRL-
PRR1_Scer -------------LEAW---LIQRIFTEVVLAVKYLHEN--SIIHRDLKLENILLKYSFD
MEK1_Scer -------------MSET---ESLLIVFQILQALNYLHDQ--DIVHRDLKLDNILLCTPE-
VACAMKL_Mmus --------------SER---DTSNVVRQVLEAVAYLHSL--KIVHRNLKLENLVYYNRL-
YKL171W_Scer -------------FAER-CRLTIFLSLQLLSALKYMHSK--TIVHGDIKLENCLLQKEG-
YMR291W_Scer -------------DLET---QVTSYCACLVSVLEFLHSQ--GIVHRDLKAENVLFRLRVN
5683_Tthe -------------FTES---EVAFIVRKLLSALSHMHNL--GIIHRDIKLENIMINESN-
CC1G_13697_Ccin -------------LCEA---E---------------------------------------
CC1G_07362_Ccin TPSLLSNLHPSQLLSRTRLRLIASMFSQMCDAVAACHST--QVFHRDIKPENFIVTDGWV
CC1G_09141_Ccin -------------LSES---VLRRIWCEICRAVGWMHSV--GIVHRDIKLENVLLTWDGL
CC1G_07180_Ccin --------------PQD---DAGMMFRQVVRGLRYLHEV-AGLVHRDIKLENVLVDES--
AqueK053_Aque ------------------------------------------------------------
GK018_Glam -------------RTEH---ELLTILLQIAEALKYLHTLDSPITHNDISLRNILLAEG--
VACAMKL_Hsap -----------------------------K--NSKIVISDFHLAKLENG-----------
PRR1_Scer DI-NSFRD-----S-------------PIYCKQNFIELADFGLCKKIENN----------
MEK1_Scer -----------------------------P--CTRIVLADFGIAKDLNSN----------
VACAMKL_Mmus -----------------------------K--NSKIVISDFHLAKLENG-----------
YKL171W_Scer -----------------------------KKSDWKVFLCDFGMSCHFDEKH-VY-RN---
YMR291W_Scer ENEKNLQGEHHGDF-------------KYDLLAHDLVLADFGLAAEYNT-----------
5683_Tthe ---------------------------------LDVKILDFGLSRDFSQ-----------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin M-LANG----------------------RQERKVIVKLTDFGLSTTDID-----------
CC1G_09141_Ccin QSYSNLISTELSSTPTESSILSIPRPTVADLPTPIVKLTDFGLSRFIDIGNGE-------
CC1G_07180_Ccin ---------------------------------GVCRIGDFGLSVRIGDVDDEDGMDHHH
AqueK053_Aque ----------------------------------KENVTDFGLSHMKGL-----------
GK018_Glam ---------------------------------GVWKLSDFTLVKPLADK----------
VACAMKL_Hsap ------------------------------------------------------------
PRR1_Scer ------------------------------------------------------------
MEK1_Scer ------------------------------------------------------------
VACAMKL_Mmus ------------------------------------------------------------
YKL171W_Scer ---DTFDENLSSGNSHRKRKSIEQTNLIKYPTTNFLPDDRTNDFDASENLKYQFENRKHQ
YMR291W_Scer ------------------------------------------------------------
5683_Tthe ------------------------------------------------------------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin ------------------------------------------------------------
CC1G_09141_Ccin ------------------------------------------------------------
CC1G_07180_Ccin HEHHPI-DGACTGNIHR-------------------------------AVSLSFPSKRHR
AqueK053_Aque ------------------------------------------------------------
GK018_Glam ------------------------------------------------------------
VACAMKL_Hsap ------------------------------------------------------------
PRR1_Scer ------------------------------------------------------------
MEK1_Scer ------------------------------------------------------------
VACAMKL_Mmus ------------------------------------------------------------
YKL171W_Scer PFTPKGMVSSSSHSLKHLNQPSSSSSSNLFHKPASQPQPQHRSPFHGRHKTTDFSNL---
YMR291W_Scer -----------------------------------------------------------S
5683_Tthe -----------------------------------------------------------S
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin ------------------------------------------------------------
CC1G_09141_Ccin ----------------------------------------------------------RG
CC1G_07180_Ccin AATTLGAAIARHNST---------------------------------------RNRHAG
AqueK053_Aque ------------------------------------------------------------
GK018_Glam -----------------------------------------------------------K
VACAMKL_Hsap ---LIKEPCGTPEYLAPEVVGRQ-------------------------------------
PRR1_Scer --EMCTARCGSEDYVSPEILMGV-------------------------------------
MEK1_Scer K-ERMHTVVGTPEYCAPEVGFRANRKAYQ------SFS----------------------
VACAMKL_Mmus ---LIKEPCGTPEYLAPEVVGRQ-------------------------------------
YKL171W_Scer EP-EPSKYIGSLPYASPELLRYSDARR-SKSVEMHIYDSPDSSQSEISAASSSSSNLSSL
YMR291W_Scer KVNSLKEFVGTISYIAPEIVKCKGVGE-M------TPD----------------------
5683_Tthe QASILQSIVGTPLYVAPEVINEQ-------------------------------------
CC1G_13697_Ccin -------SNGSHPFDND-------------------------------------------
CC1G_07362_Ccin ---SSDVDCGSAPYMSYECRNNIAP-----------------------------------
CC1G_09141_Ccin QGEMLNTRCGSEAYAAPELVMGGGPR----------------------------------
CC1G_07180_Ccin QS-SHVYQPGSLPYAAPELLLPNTAD----------------------------------
AqueK053_Aque --------PGC-------------------------------------------------
GK018_Glam EVQMVTSLAGTKPFTAPEKLLQ--------------------------------------
*
VACAMKL_Hsap ---------------------------------RYGRPVDCWAIGVIMYILLSGNPPFYE
PRR1_Scer --------------------------------PYDGHLSDTWALGVILYSLFEDRLPFDP
MEK1_Scer ----------RAATL---------------EQRGYDSKCDLWSLGVITHIMLTGISPFYG
VACAMKL_Mmus ---------------------------------RYGRPVDCWAIGVIMYILLSGNPPFYE
YKL171W_Scer SSSTKASAVTNS--GVTTSSPSGSSTDFPCIVSPLGPASDIWALGVMLYTMLVGKLPFNH
YMR291W_Scer ----------QV--G---------------KLDKYGCPVDIWALGVLTYFMAFGYTPFDC
5683_Tthe ---------------------------------PYDQKSDSWSMGVLMYYLISGSHPFEA
CC1G_13697_Ccin -----------------------------------ATYQSSWADDADSYTSV----PTES
CC1G_07362_Ccin --------------------------------TYRPRDADVWSLGIVLINMLYHFNPWTD
CC1G_09141_Ccin -------------------------------GVYDGRETDAWACGVVLYALVGRKLPFGE
CC1G_07180_Ccin -------------------------------MAPAHPGQDIWALGVMLYALLTGHLPFND
AqueK053_Aque --------------------------------------------DDLMSSSLCGRMPFNA
GK018_Glam --------------------------------GVFGPASDMYSYGVVAFACFVGNINLFL
.
VACAMKL_Hsap EVEEDD-------------------YEN-----HDKNL-----FRKILAGD-YEF-----
PRR1_Scer PPNAS----------------------ARQ---RSRAT-----SHRIARFD-WR------
MEK1_Scer DGSE-------------------------------RSI-----IQNAKIGK-LNF-----
VACAMKL_Mmus EVEEDD-------------------YEN-----HDKNL-----FRKILAGD-YEF-----
YKL171W_Scer EFEPR-----------------------------LRSL-----I-KVGEFDRFSLAQVCK
YMR291W_Scer TTDD--------------------------------ET-----LECISKCD-YYV-----
5683_Tthe SNI--------------------------------KEL-----FKNICSAN-FNF-----
CC1G_13697_Ccin QQCLGS-------------------FSE----HRQARL-----KARIVEEE-VVF-----
CC1G_07362_Ccin TAEG--------------------------------ACSSFDLYRR---DP-VNF-----
CC1G_09141_Ccin GVGIGMDGGHGTQSHINGERVHPPGYSSRKHAVERRAW-----LMRIAKGE-YEW-----
CC1G_07180_Ccin SFEP--------------------------------RL-----QMKILNGT-FEI-----
AqueK053_Aque ETAP--------------------------------LL-----EEQIMCGA-LKF-----
GK018_Glam APNN---------------------F----AEIPGRGS-----LMDRARAD-LCS-----
VACAMKL_Hsap -DSP-Y----------------WDDISQA-A----KDLVT---RLMEVEQ--DQRITAEE
PRR1_Scer ----------------------WYRLSDY-KTNVGKQIVE---NTLTR-K--NQRWSINE
MEK1_Scer -KLK-Q----------------WDIVSDN-A----KSFVK---DLLQTDV--VKRLNSKQ
VACAMKL_Mmus -DSP-Y----------------WDDISQA-A----KDLVT---RLMEVEQ--DQRITAEE
YKL171W_Scer FDRKKN----------------EGTIGQG-L----YDTVI---GCLTIDL--DKRWKLKR
YMR291W_Scer -DEQ-MMH---------------DPKYEQ-F----WNFVQ---CCFTIDP--AVRRSAKN
5683_Tthe -RSS-A----------------WSGISKS-A----KVLIT---QFLNLDP--KSRISCEE
CC1G_13697_Ccin -LHC-P----------------WSNLPQ--A----KALVQ---NLLVHDY--RRRANVFE
CC1G_07362_Ccin -FTN-R----------------FPGMTRGVA----EFLASRVFCILEGDESEGRRISAAD
CC1G_09141_Ccin -PEV-PSDAAAVEDGDGELVGPRLALSEG-A----KRVVG---RLLVRDP--KKRARIVD
CC1G_07180_Ccin -PA---------------------DIGRG-A----ERILQ---GCMERII--TKRWTIAM
AqueK053_Aque -KEP-E----------------WISISDG-A----KELVR---GMLNVST--INRMTARQ
GK018_Glam -GTC-YV----------------CNPSDR-V----VDLIT---NLLCLDM--NARMTAEQ
: *
VACAMKL_Hsap -----------------------------------AISHEWISGNA-ASD-----KNIKD
PRR1_Scer -----------------------------------IYESP--------------------
MEK1_Scer -----------------------------------GLKHIWIAKHL-SQLER---LYYKK
VACAMKL_Mmus -----------------------------------AISHEWISGNA-ASD-----KNIKD
YKL171W_Scer -----------------------------------IEEVL--------------------
YMR291W_Scer -----------------------------------LKQHPFIKDYF-ATSNS---LNTKD
5683_Tthe -----------------------------------ALQSDWFSVYL-KNQ-----INYKS
CC1G_13697_Ccin -----------------------------------ALDSEWMVSEI-SDLQ---------
CC1G_07362_Ccin FGVWVKDNLVTMLAGHGMQRTLSTSSTQGHPITSIPVSHRPMSRNP-SNA------TAAR
CC1G_09141_Ccin -----------------------------------LWEDDWMRGDE-IGL-----GMWEA
CC1G_07180_Ccin -----------------------------------VDEVSWGVGWGSAGDNATPDESQED
AqueK053_Aque -----------------------------------VLEDSWITGGA-VRK------RI--
GK018_Glam -----------------------------------VCQT---------------------
.
VACAMKL_Hsap G---VCA-------------------------------QIEKNF--ARAKW-------KK
PRR1_Scer ------------------------------------------------------------
MEK1_Scer I---LCN-------------------------------NEGPKLESINSDW-------K-
VACAMKL_Mmus G---VCA-------------------------------QIEKNF--ARAKW-------KK
YKL171W_Scer ------------------------------------------------------------
YMR291W_Scer ----------------------------------------TPNF--SFHPT-------IR
5683_Tthe RNMKKCL-------------------------------SKIQNF--I--SF-------QN
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin G---TPA-------------------------------MPTRSL--SRAPSLGPAYEREE
CC1G_09141_Ccin ----I---------------------------------Q---------------------
CC1G_07180_Ccin L---LAFHAITSPLSAKSCSESRLDRLTIPESDEDDWQHEEHHF--TRSAI-------EA
AqueK053_Aque ------------------------------------------------------------
GK018_Glam ------------------------------------------------------------
VACAMKL_Hsap AVRVT-TLMK-----R--LRAPEQSS------TAAAQ-----SAS-ATDTATPGAAGGAT
PRR1_Scer ------------------------------------------------------------
MEK1_Scer ------------------------------------------------------------
VACAMKL_Mmus AVRVT-TLMK-----R--LRAPEQSG------TAATQ-----SA---SDAATPGAAGGAI
YKL171W_Scer ------------------------------------------------------------
YMR291W_Scer RVSST-ASMH-----T--LRSPSKSR------KTTTLA-------------YLNMDGGSS
5683_Tthe SFKFK-QEII-----R--LMFNTQTQ------TDEIQ-----KLKIAFETIDT-DDNGYI
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin KSELS-TVIDQDNEDD--VEVPEPSEPILGVEEAGSR-----SAS-TSKRRKRGARKGKG
CC1G_09141_Ccin ------------------------------------------------------------
CC1G_07180_Ccin GSRRSSSRAK-----RSQSRAPMSAR------SHSRQCSPHRSAR-SSSRMYSGFSSAAV
AqueK053_Aque ------------------------------------------------------------
GK018_Glam ------------------------------------------------------------
VACAMKL_Hsap AAAA-------------------------SGA-----TSAPEGDAARAA-----------
PRR1_Scer ------------------------------------------------------------
MEK1_Scer ------------------------------------------------------------
VACAMKL_Mmus AAAAAAA-----------AAGGAASA-SGASA-----TAATEGGAGCAA-----------
YKL171W_Scer ------------------------------------------------------------
YMR291W_Scer ETSTA-------------------------FSSKMD---LPDLY----------------
5683_Tthe SAEE--------------------------------------------------------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin AQASSPTSPQDDTIVNLAAASECL-ARELSKQSKVSLPSSPKSTSTSSRKRQPLEPVSMY
CC1G_09141_Ccin ------------------------------------------------------------
CC1G_07180_Ccin SRSH--------------------------------------------------------
AqueK053_Aque ------------------------------------------------------DPLMML
GK018_Glam ------------------------------------------------------------
VACAMKL_Hsap ----------------------------------------------KSDNVAPADRSATP
PRR1_Scer ------------------------------------------------------------
MEK1_Scer ------------------------------------------------------------
VACAMKL_Mmus ----------------------------------------------KSDDIASADRSATP
YKL171W_Scer ------------------------------------------------------------
YMR291W_Scer ----------------------------------------------VDRTINSRERSLN-
5683_Tthe ------------------------------------------------------------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin AMPTP--LLNSSTPRTATKASTFVTCTPVPPSAPTKKPSRWKLSFGKANASTLANAVERP
CC1G_09141_Ccin -----------------------------------------------------LDRNASD
CC1G_07180_Ccin ------------------------------------------------------------
AqueK053_Aque ADDSPPPHPHSSSHKTSDTSP---------------------------PTISISDKDTPP
GK018_Glam ------------------------------------------------------------
VACAMKL_Hsap -ATDGSATPAT-------------------------------------------------
PRR1_Scer ------------------------------------------------------------
MEK1_Scer ------------------------------------------------------------
VACAMKL_Mmus -ATDGSATPAT-------------------------------------------------
YKL171W_Scer ------------------------------------------------------------
YMR291W_Scer RIRDTLKKTLS-------------------------------------------------
5683_Tthe --------------------------------------------------------LFKA
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin -ATEEAASPASAEPSQPPPPSTTVNNVTNLIMGLDAPAARPIPPAAGVFDDGASTWARGR
CC1G_09141_Ccin RVSDG-------------------------------------------------------
CC1G_07180_Ccin -------SPATSPLFENPPSRSRSQS-----------------------------RHRGR
AqueK053_Aque -STTGGG--------------------------------------------GGGGDAKGR
GK018_Glam ------------------------------------------------------------
VACAMKL_Hsap -------------DGSVTPAT--DGSI------------------------T--------
PRR1_Scer ------------------------------------------------------------
MEK1_Scer ------------------------------------------------------------
VACAMKL_Mmus -------------DGSVTPAT--DGSI------------------------T--------
YKL171W_Scer ------------------------------------------------------------
YMR291W_Scer -------------MTSLKPAG--TFDY------LHANKNGTSLSSSKSGLVK------KN
5683_Tthe T------------QQLNIPITQK--QIYALFQEINCHKINNAFKISQEIDVN------QD
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin R------------PRDASPVRKYGGRS------------------------PRRGLQSPS
CC1G_09141_Ccin -----------------------SGEV------------------------K--------
CC1G_07180_Ccin QPNKRCYFASRSPSPSWVPST--PSDI------SHIS----------RLSLR-----EPS
AqueK053_Aque L------------NKSPTPVQMKSASL------------------------P--------
GK018_Glam ------------------------------------------------------------
VACAMKL_Hsap -------------------------PATD---G-----------------SVTPATDRS-
PRR1_Scer ------------------------------------------------------------
MEK1_Scer ------------------------------------------------------------
VACAMKL_Mmus -------------------------PATD---G-----------------SVTPATDRS-
YKL171W_Scer ------------------------------------------------------------
YMR291W_Scer ----S----------TF---VL-D-PKPP---KNSLMNGCF---------STTPESRSNF
5683_Tthe ----ENKQQNYIHYSDFIYASINLSKELD---Q-EKINQLFSHFDKDGDNFISPQ-DLE-
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin QPSLA----------DS---WV-D-PPSRGPSR-----------------AISPSSTRS-
CC1G_09141_Ccin -------------------------PATN---E-------------------NPITVLK-
CC1G_07180_Ccin ----E----------DL---HL-D-SPPRGRTR---------------------------
AqueK053_Aque -------------------------RSTS---A-----------------NRMPLMTSK-
GK018_Glam ------------------------------------------------------------
VACAMKL_Hsap ATP---------------------ATDGRATP-ATEESTVPTTQSSAML-------ATKA
PRR1_Scer ------------------------------------------------------------
MEK1_Scer ----------------------------RKLP----------------------------
VACAMKL_Mmus ATP---------------------ATDGRATP-ATEESTVPATQSSALP-------AAKA
YKL171W_Scer ------------------------------------------------------------
YMR291W_Scer NTP---------------------KTLSRQGS-STSVKKYV--------------NEVDL
5683_Tthe DTF---------------------AQEGRKLP-EQ-------------------------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin GRPIRSSASSMASSNWR-SSMSTTSSAGTSTSAFTH-YSNGSTRSISTT-------ATSV
CC1G_09141_Ccin EDG---------------------LDDGEWEP-LDEDEYLEEED----------------
CC1G_07180_Ccin --------FSLHHETFDEGDEATEGVEGGGALKLTH-AADGTGQCSATDWTSRITAEAED
AqueK053_Aque ---------------------KTGGAMGGASSGPTHKKTVSSSISTGRL-----------
GK018_Glam ------------------------------------------------------------
VACAMKL_Hsap AAT------PEPAMAQPDS-------------------------------TA-------P
PRR1_Scer ------------------------------------------------------------
MEK1_Scer ------------------------------------------------------------
VACAMKL_Mmus AAT------PEPAVAQPDS-------------------------------TA-------L
YKL171W_Scer ------------------------------------------------------------
YMR291W_Scer LLT-PRT----ASMSSNDT-------------------------------TA-IND----
5683_Tthe ------------------------------------------------------------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin SATSWRTSVKQPSISSNSSGYSASGGYTSVPKNIKLMNGVPWELDQLPRGQH-------P
CC1G_09141_Ccin ------------------------------------------------------------
CC1G_07180_Ccin HVS------PERASSRPNI-------------------------------RSSWTEIPFR
AqueK053_Aque ------------------------------------------------------------
GK018_Glam ------------------------------------------------------------
VACAMKL_Hsap EGATGQAPPSSK------------------------------------------------
PRR1_Scer ------------------------------------------------------------
MEK1_Scer ------------------------------------------------------------
VACAMKL_Mmus EGATGQAPPSSK------------------------------------------------
YKL171W_Scer ------------------------------------------------------------
YMR291W_Scer YDTTNDKNPARK------------------------------------------------
5683_Tthe --SIRQMIEEVD---VDGD-------------G---------------------------
CC1G_13697_Ccin ------------------------------------------------------------
CC1G_07362_Ccin DPSFGNPPPRKQRTRKHKDIK----------------LDTITERPSNSAGLKSPELRKDA
CC1G_09141_Ccin ---------------EH-------------------------------EGWL--------
CC1G_07180_Ccin NSRPGSTPPASSKT-----WELFRNKASHGLLSRNPSQ-------DMCLGFPSPGLG---
AqueK053_Aque ------------------------------------------------------------
GK018_Glam ------------------------------------------------------------
VACAMKL_Hsap ----------------------G-------EEA-AGYAQ---ESQREEAS
PRR1_Scer ----------------------------------F-VKT---IADTLSFS
MEK1_Scer -------------------------------KS-VIISQ-AIPKKKKVLE
VACAMKL_Mmus ----------------------G-------EEA-TGCAQ---ESQRVETS
YKL171W_Scer ------------------------------QNE-MNLSE---AIHDNNGS
YMR291W_Scer ----------------------H--A-ASFQVN-V-DDS---DGDETMQI
5683_Tthe -----------KI-------SQQ-EFLQLVQQE-IEIFQKTRTSFTNLEI
CC1G_13697_Ccin ------------------------------------LLY---RRKILGNK
CC1G_07362_Ccin MTSTSDLPAVVNAARDEGDNVGSGGVKKVHKGQ-INALA---KMLSALRR
CC1G_09141_Ccin -----------L-------------------DE-Q-SIS---SIVRQEVV
CC1G_07180_Ccin ------TPGIISR---------SRSIDQYHDPTRTAKVE---IPPASSCA
AqueK053_Aque -----------QSTRGRGGGGGGGGAG--------GGAN---SRKLSARN
GK018_Glam ------------------------------LSE-M-LSG---YRKTKIKI