Gene YSK (S.moellendorffii)

YSK

Species: S.moellendorffii
Alias: YSK
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: YSK

Sequence

Name Sequence Type Origin Length Description Download
YSK.AA Protein None 698 None Fasta, JSON
YSK.NA RNA None 2097 None Fasta, JSON
YSK.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of YSK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase YSK.AA YSK 39-291 63 2.9e-197 599.93 In-house 1-257 (257) Show / Hide 
Range on Protein: 39-291
Range on HMM: 1-257/257
Sequence Identity: 63% (162 aa)

FDNLQLIGKGSFGDVFKGFDKELNKEVAIKVIDLEEAEDEIDEIQKEISVLSQCRSPYITEYYGSFLHGTKLWIVMEYMAGGSVSDLLETG--NPLDELS
|  .  ||.||||.|.|| |.  .. ||||.||||.|||||. ||.|| .|||| ||||| ||||.| .|||||.||| .|||..||.     ...||  
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

IACIIRDLLHALDYLHSEGKIHRDIKAANILLTANGDVKVADFGVSAQLTRTVSKRKTFVGTPFWMAPEVIQNS-DGYNEKADIWSLGITTIEMAKGEPP
|| |.| .| .||||||| ||||||||||.||...||||..||||..|.| |. || ||||||.|||||||.   ..|..||||||||||..||||||||
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPP

FADLHPMRVLFLIPKNNPPQLED-HFSRPMKEFVSLCLKKNPAERASAKELLKHRFV
 .|.|||||.|||||||||.||. ..| ..|||| .||.|.|..| ||||||||.|.
YCDYHPMRVMFLIPKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase YSK.AA STE20 39-291 50 2.6e-161 542.18 In-house 1-288 (288) Show / Hide 
Range on Protein: 39-291
Range on HMM: 1-288/288
Sequence Identity: 50% (144 aa)

FDNLQLIGKGSFGDVFKGFDKELNKE----VAIKVIDLEEAE---DEIDEIQKEISVLSQCRSPYITEYYGSFLHG----TKLWIVMEYMAGGSVSDLLE
...|. ||.||.|.|.|. .|. ...    ||||...||...   ||...||||||...||..|.|..||||.| .    ..|||||||..|||..|...
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

----TGN-----PLDELSIACIIRDLLHALDYLHSEGKIHRDIKAANILLTANGDVKVADFGVSAQLTR----TVS-KRKTFVGTPFWMAPEVIQN----
    .|.     |..|  ||.| |..| .||||||...|||||||.||||| .|.|| |||||.||||.    | . ||.||||||.||||||||     
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

SDGYNEKADIWSLGITTIEMAKGEPPFADLHPMRVLFLIP--KNNPPQLED----HFSRPMKEFVSLCLKKNPAERASAKELLKHRFV
  ||..|.||||||||.||||.||||..|.||||..|.||  .| || |.|    ..|   ..||..|| |.|..|..|..|||| |.
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase YSK.AA STE 39-291 35 3.7e-139 468.61 In-house 1-359 (359) Show / Hide 
Range on Protein: 39-291
Range on HMM: 1-359/359
Sequence Identity: 35% (130 aa)

FDNLQLIGKGSFGDVFKGFDK------ELNKE---------VAIKVIDLEEAE----------------DEIDEIQKEISVLSQCR--SPYITEYYGSFL
..... ||||.|| |.|. ..      . ...         .|||...||. .                .|...|.|||.....|.  .|.| .|||...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

HG-------TKLWIVMEYMAGGSVSDLLE----TGNPLD----------ELSIACIIRDLLHA-LDYLHSEGKIHRDIKAANILLTANGDVKVADFGVSA
..       ..|||.||||.|||..|...    .|.||.          |  ||.|.|..|.. |.|||| ..||||||.|||||     || .||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLTR---------------TVS-KRKTFVGTPFWMAPEVIQN-----SDGYNEKADIWSLGITTIEMAKGEPPFADLHPMRVLFLIPKN-----------
|||                | . ||.|||||| ||||||||.     ..||..|.||||||.| |||| |.||..|.||||..|.||.|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----NPPQLED-------------------HFSRPMKEFVSLCLKKNPAERASAKELLK--HRFV
    .||.|.|                   ..| ..|.|...||.|.| .|..|..|||  | |.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase YSK.AA MST 39-291 51 3.4e-133 425.74 In-house 1-254 (254) Show / Hide 
Range on Protein: 39-291
Range on HMM: 1-254/254
Sequence Identity: 51% (134 aa)

FDNLQLIGKGSFGDVFKGFDKELNKEVAIKVIDLEEAEDEIDEIQKEISVLSQCRSPYITEYYGSFL--HGTKLWIVMEYMAGGSVSDLLE-TGNPLDEL
|| . ..| ||.| |.|  .|. .|.||||..  .|    ..|| |||| ..|| |.||  ||||..    . .|||||| ..|||.|.   |. .| | 
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNE---DLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQ

SIACIIRDLLHALDYLHSEGKIHRDIKAANILLTANGDVKVADFGVSAQLTRTVSKRKTFVGTPFWMAPEVIQNSDGYNEKADIWSLGITTIEMAKGEPP
 |||| .| |  |.|||.  ||||||||.||||   |  | ||||||.||| |  || |..|||.||||||||.. .|. |||||||||| |||| |.||
QIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEI-KYDCKADIWSLGITAIEMAEGMPP

FADLHPMRVLFLIPKNNPPQLED--HFSRPMKEFVSLCLKKNPAERASAKELLKHRFV
..|.||||..|.||.. || . |   .|     ||. || ||| .|..|..||.| |.
YSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase YSK.AA FRAY 41-291 41 1.2e-106 332.35 In-house 2-277 (277) Show / Hide 
Range on Protein: 41-291
Range on HMM: 2-277/277
Sequence Identity: 41% (115 aa)

NLQ-LIGKGSFGDVFKGFDKELNKEVAIKVIDLEEAE-DEIDEIQKEISVLSQCRSPYITEYYGSFLHGTKLWIVMEYMAGGSVSDLL----ETGNP---
.||  ||.|  . |.|   . .. ..|||.|.||  .   .||. ||| . .||  | . .|. ||.    ||.|| |  .||..|..    ..|.|   
ELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHKQ

--LDELSIACIIRDLLHALDYLHSEGKIHRDIKAANILLTANGDVKVADFGVSAQLTR-----TVSKRKTFVGTPFWMAPEVIQNSDGYNEKADIWSLGI
  .|| .|| | ...| .|.|.|. |.||||||| |||.  .| . .||||||| |       .   |.|||||| ||||||.    ||. ||||||.||
GVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCVRHTFVGTPCWMAPEVMEQVHGYDFKADIWSFGI

TTIEMAKGEPPFADLHPMRVLFLIPKNNPPQLEDH---------FSRPMKEFVSLCLKKNPAERASAKELLKHRFV
| ||.|.| .|.... || || |.  |.|| ||           ...  |. .. || | |. |  | |||||.| 
TAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase YSK.AA PAKA 39-291 41 1.9e-106 359.91 In-house 1-260 (260) Show / Hide 
Range on Protein: 39-291
Range on HMM: 1-260/260
Sequence Identity: 41% (110 aa)

FDNLQLIGKGSFGDVFKGFDKELNKE--VAIKVIDLEEAEDEIDEIQKEISVLSQCRSPYITEYYGSFLHGTKLWIVMEYMAGGSVSDLLETGN-----P
..... ||.|. | |... ... |.|  ||||...... .. .. |  ||.|. .|. . |  |. |.|   .||.|||||.||.  |...  .     .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKN-QPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNY

LDELSIACIIRDLLHALDYLHSEGKIHRDIKAANILLTANGDVKVADFGVSAQLTRTVSKRKTFVGTPFWMAPEVIQNSDGYNEKADIWSLGITTIEMAK
.||  ||...|  | .|...||.. ||||||  |||| ..|.||..|||  ||||.  .||.| |||| |||||||.  . |.|| ||||||| .|||. 
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQ-YDEKVDIWSLGIMAIEMIE

GEPPFADLHPMRVLFLIPKN-NPPQLE-DHFSRPMKEFVSLCLKKNPAERASAKELLKHRFV
||||. .  | | ..|| .|  |. .. | .|  ...|...||.... .||||.|||.| | 
GEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase YSK.AA KHS 39-291 51 5e-106 357.64 In-house 1-258 (258) Show / Hide 
Range on Protein: 39-291
Range on HMM: 1-258/258
Sequence Identity: 51% (134 aa)

FDNLQLIGKGSFGDVFKGFDKELNKEVAIKVIDLEEAEDEIDEIQKEISVLSQCRSPYITEYYGSFLHGTKLWIVMEYMAGGSVSDLLETGNPLDELSIA
.. || .| | .|||.|  |.. .. .|.||| . |..|..  ||.|| .. .|| | |  |.||.|.  ||||.|||  |||. |. .   || || ||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKM-EPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGPLSELQIA

CIIRDLLHALDYLHSEGKIHRDIKAANILLTANGDVKVADFGVSAQLTRTVSKRKTFVGTPFWMAPEV--IQNSDGYNEKADIWSLGITTIEMAKGEPPF
 . |. |..|.||||.||.||||| |||||| .||||.||||||||.| |..||| |.|||.||||||  ..   |||.  |||..||| ||.|   ||.
YVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPM

ADLHPMRVLFLIPKNN--PPQLED--HFSRPMKEFVSLCLKKNPAERASAKELLKHRFV
 ||||||.|||. | |  ||.|.|  ..|    .|| ..| |||  | .|. ||.| ||
FDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase YSK.AA PAKL 46-291 45 7.29999999999e-102 344.71 In-house 8-256 (256) Show / Hide 
Range on Protein: 46-291
Range on HMM: 8-256/256
Sequence Identity: 45% (114 aa)

GKGSFGDVFKGFDKELNKEVAIKVIDLEEAEDEIDEIQKEISVLSQCRSPYITEYYGSFLHG-TKLWIVMEYMAGGSVSDLLE-TGNPLDELSIACIIRD
| ||.| |.|.  |..|   ||||| . |.  || .|.|||..|  |..|.|  |.||   . ...|| |.| . ||. |..| ..  |.|  |. |.. 
GQGSYGSVYKAIHKDTNFPLAIKVIEIKESN-EIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQISVILQQ

LLHALDYLHSEGKIHRDIKAANILLTANGDVKVADFGVSAQLTRTVS-KRKTFVGTPFWMAPEVIQNSDGYNEKADIWSLGITTIEMAKGEPPFADLHPM
 |  | |||| . ||||||||||||.  ..||.|||||| ||  . .   .  .|||.|||||.|   . || |.|||||||| |||| |.||  |. ||
TLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQN-YNNKCDIWSLGITAIEMADGFPPHYDMPPM

RVLFLIPKNNPPQLED--HFSRPMKEFVSLCLKKNPAERASAKELLKHRFV
| .  ||   || . .  |.|  .  |.  |. | | .|.|. .|| | | 
RAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase YSK.AA S_TKc 39-291 33 9.60000000001e-102 345.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 39-291
Range on HMM: 1-231/231
Sequence Identity: 33% (89 aa)

FDNLQLIGKGSFGDVFKGFDKELNKEVAIKVIDLEEAEDEIDEIQKEISVLSQCRSPYITEYYGSFLHGTKLWIVMEYMAG--GSVSDLLETGNP-----
.. |..||||.|| |.|. .|. ...||||.|.        . |..||..|.. . |.|  .|..| . ..|..||||. |  |.. |...  ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LDELSIACIIRDLLHALDYLHSEGKIHRDIKAANILLTANGDVKVADFGVSAQLTRTVSKRKTFVGTPFWMAPEVIQNSDGYNE-KADIWSLGITTIEM
 ..|  ...... .. ||.|.|| | ||||.| .||||.    .|..|||...||       .||.|||..|||||.    ||.  |.|.||.|.. .||
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM

AKGEPPFADLHPMRVLFLIPKNNPPQLEDHFSRPMKEFVSLCLKKNPAERASAKELLK-------HRFV
. |.|||   ...... .|            |...|.|.. ||.|.|..| .| |.|.       | ..
LCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase YSK.AA Pkinase 39-291 29 1.2e-92 318.94 Pfam 1-293 (293) Show / Hide 
Range on Protein: 39-291
Range on HMM: 1-293/293
Sequence Identity: 29% (87 aa)

FDNLQLIGKGSFGDVFKGFDKELNKEVAIKVIDLEEAEDEIDEIQK---EISVLSQCRSPYITEYYGSFLHGTKLWIVMEYMAGG----SVSDLLE--TG
.  .. ||.|||| |.|. .|  .|.||.|.|........ |..     ||...  ...|.| ..|..|  ......||||. ||    . .|...   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NPL--DELSIACIIRDLLHALDYLHSEGKIHRDIKAANILLTANGDV----KVADFGVSAQL-TRTVSKRKTFVGTPFWMAPEVIQNSDGYNEKADIWSL
...  .|  . .... .| .|.|.||.| ||||.| .|||.  ||..    |..|||...|. .   |  .||.|||..||||||. . .|  |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GITTIEMAKGEPPFADL----HPMRVLFLIPKNNPPQLEDHFS-----------------------RPMKEFVSLCLKKNPAERASAKELLKHRFV
|.. .||. |.||| .     . .. ...| .. .|.|. ...                       ...|.|.. ||.|.|..| .|...|.| ..
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase YSK.AA STE11 39-291 34 1.1e-88 300.91 In-house 1-303 (303) Show / Hide 
Range on Protein: 39-291
Range on HMM: 1-303/303
Sequence Identity: 34% (106 aa)

FDNLQLIGKGSFGDVFKGFDKELNKEVAIKVIDL-------EEAEDEIDE------IQKEISVLSQCRSPYITEYYGSFLH---GTKLWIVMEYMAGGSV
.   ..||||.|| |.|....  ....|.| | .       |..|.|...      ||.||..... . . |  |||. ||     .. | |||..|||.
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

SDLLE-TGNP--LDELSIACIIRDLLHALDYLHSEGKIHRDIKAANILLTANGD-VKVADFGVSAQLTRTVSKRKT----------FVGTPF--------
|..|.    |  .||  |   ....| .| |||| | ||||||.||||| ..|  .| |||| . .|    .. ..          . |||.        
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

WMAPEVIQNSD--GYNEKADIWSLGITTIEMAKGEPPFADL-H-PMRVLFLIP-K-NNPPQLEDHFS------RPMKEFVSLCLKKNPAERASAKELLKH
||||||| ..   ||  |||||||| | |||| | ||.... | .|  .| |  . ...|.. .|.|       . ..|...|....| .|..| .||.|
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

RFV
 |.
PFI
Kinase YSK.AA SLK 39-291 43 5.1e-87 293.6 In-house 1-259 (259) Show / Hide 
Range on Protein: 39-291
Range on HMM: 1-259/259
Sequence Identity: 43% (113 aa)

FDNLQLIGKGSFGDVFKGFDKELNKEVAIKVIDLEEAEDEIDEIQKEISVLSQCRSPYITEYYGSFLHGTKLWIVMEYMAGGSVSD-LLETGNPLDELSI
.. .  .| | || | |  .|| ..  | |.|.... | |...   || .||.|  |.| . |... .  |||...|. .|| |   ..| . || |  |
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEE-ELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQI

ACIIRDLLHALDYLHSEGKIHRDIKAANILLTANGDVKVADFGVSAQLTRTVSKRKTFVGTPFWMAPEVI----QNSDGYNEKADIWSLGITTIEMAKGE
. . . .. ||..|||.  ||||.|| |||.| .|||..|||||||....|. || ||.|||.||||||.       . |  |||||||||| ||||..|
QYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQME

PPFADLHPMRVLFLIPKNNPPQLED--HFSRPMKEFVSLCLKKNPAERASAKELLKHRFV
||  .. |||||. | | .||.||   |.|.  |.|.  ||.|.|  | ....|..|..|
PPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase YSK.AA Pkinase_Tyr 39-291 25 3.6e-43 146.84 Pfam 1-270 (270) Show / Hide 
Range on Protein: 39-291
Range on HMM: 1-270/270
Sequence Identity: 25% (71 aa)

FDNLQLIGKGSFGDVFKGFDK----ELNKEVAIKVIDLEEAEDE---IDEIQKEISVLSQC-RSPYITEYYGSFL-HGTK--LWIVMEYMAGGSVSDLLE
   .. .|.|.||.|.||  |    . . .||.|..  | | .|   ...  .|.....|  . | |  .||  . .|    ..||||||..|.  | | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

T----GNPLDELSIACIIRDLLHALDYLHSEGKIHRDIKAANILLTANGDVKVADFGVSAQL-----TRTVSKRKTFVGTPFWMAPEVIQNSDGYNEKAD
.    ..||.   . .. ..   ...||.| . ||||. | |.|.| |. ||..||| .  .       .... ..     .|||||.|...  ...| |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGK-LPIKWMAPECINYGK-FTTKSD

IWSLGITTIEMAK-GEPP-FADLHPMRVLFLI-PKNNPPQLEDHFSRPMKEFVSLCLKKNPAERASAKELLKHRFV
.|| |..  |.   || | .... . .|. .|  ...     .. . .. .   .| ...|..| . .|.  |.. 
VWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase YSK.AA TyrKc 39-290 24 4e-29 104.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 39-290
Range on HMM: 1-280/280
Sequence Identity: 24% (71 aa)

FDNLQLIGKGSFGDVFKGFDKELNKEVAIKVIDLEEAEDEIDEIQKEISVLSQC--RSPYITEYYGSFLHG-------TKLWIVMEYMAGGSVSDLLETG
   .. .| | || |.||  |    .||.|..  .     . .. .|......   . | |   ||  ...         |.||||||..|.  | |   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

NP-LDELSIACIIRDLLHALDYLHSEGKIHRDIKAANILLTANGDVKVADFGVSAQLTRT-------VSKRKTF-VGTP-----FWMAPEVIQNSDG-YN
 | |       .  .     .|||| . ||||. | |.|...|. ||..||| |  ..           .||.   |.       |||||.|   .| ..
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFT

EKADIWSLGITTIEMA-KGEPPFAD-----LHPMRVLFLIPKNNPPQLEDH--------FSRPMKEFVSLCLKKNPAERASAKELLKHRF
.| |.|| |..  |.   |..|  .     . . .|. .. . . .   ..         .  | .  . | . .|..| . .|. ...|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF