Gene STE11-p2_j (S.moellendorffii)
STE11-p2_j
Species: S.moellendorffii
Alias: STE11-p2_j
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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STE11-p2_j.AA | Protein | None | 186 | None | Fasta, JSON |
STE11-p2_j.NA | RNA | None | 561 | None | Fasta, JSON |
STE11-p2_j.kin_dom | Protein Kinase Domain | None | 179 | None | Fasta, JSON |
Protein domains of STE11-p2_j.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | STE11-p2_j.AA | STE11 | 4-179 | 41 | 4e-66 | 226.0 | In-house | 99-303 (303) | Show / Hide |
Range on Protein: 4-179 Range on HMM: 99-303/303 Sequence Identity: 41% (86 aa) SLASVIK-ESNG--LDESKLRVYTRQILSGLEYLHRMNIVHSRDVKCGNILLDPNGK-AKLADFGLAKKHRSHQIDYSV-------AKSCKGTFV----- ||.|... .||. |.||.|||.|| ||| .|.| ||.| ||||| .| |||||| ||.. .. . || .||. SLSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIH-RDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMG ---YMAPEVLLTEGT--YGLAADVWSLGCTVIEMACGKPPWSGFGV--RSLTFTSMRD-GCSPPIPPKMS------TEAVSFIKLCLTRDPRRRPSAAAL .|||||. ||. || .||.|||||||||||.|||||.... | . . |||| .|| |. |...|...|| ||.|. | TPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQL LSHPFF | |||. LQHPFI |
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Kinase | STE11-p2_j.AA | STE11-Unclassified | 15-179 | 35 | 1.7e-63 | 217.22 | In-house | 104-308 (308) | Show / Hide |
Range on Protein: 15-179 Range on HMM: 104-308/308 Sequence Identity: 35% (73 aa) LDESKLRVYTRQILSGLEYLHRMNIVHSRDVKCGNILLDPNGKAKLADFGLAKKHRSH----------------QIDYSVA------KSCKGTFV---YM .||.. ..||.|||.||.||| .|.| ||.| .|||.| .| .||.|||.||.. .| ... || .|| .| FDEMVIKKYTKQILEGLAYLHSHGIIH-RDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPFWM APEVLLT--EGTYGLAADVWSLGCTVIEMACGKPPWSGFGV---RSLTFTSMRDGCSPPIPPKMS-----------TEAVSFIKLCLTRDPRRRPSAAAL ||||. . .. .. ..|.||||||||||| ||.|||.. . . .. .. |.|| ..| .|. |. .|...|| ||.| | APEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPTANQL LSHPFF |.||| LQHPFI |
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Kinase | STE11-p2_j.AA | STE | 4-179 | 30 | 8.4e-63 | 214.95 | In-house | 123-359 (359) | Show / Hide |
Range on Protein: 4-179 Range on HMM: 123-359/359 Sequence Identity: 30% (75 aa) SLASVIKES----NGLD----------ESKLRVYTRQILSG-LEYLHRMNIVHSRDVKCGNILLDPNGKAKLADFGLAKKHRSHQI------------DY || ..||. ..|. || .....|||| | |.|||...|.| ||.|..|||| .||.|||.... .. . SLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIH-RDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETM S-VAKSCKGTFVYMAPEVLLT-----EGTYGLAADVWSLGCTVIEMACGKPPWSG-FGVRSLTFTSMRDGCS-------------PPIPP---------- . ... || .|||||.. .. |. .|.||||||.||||.|||||. | . . . ... ||.|. QQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISY ---------KMSTEAVSFIKLCLTRDPRRRPSAAALLS--HPFF |.| | ||..||..||. ||.| ||. |||. GGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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Kinase | STE11-p2_j.AA | AGC | 15-179 | 27 | 5.1e-60 | 152.84 | In-house | 143-395 (395) | Show / Hide |
Range on Protein: 15-179 Range on HMM: 143-395/395 Sequence Identity: 27% (71 aa) LDESKLRVYTRQ-------ILSGLEYLHR-MNIVHSRD-VKCGNILLDPNGKAKLADFGLAKK-----------------HRSHQIDY------------ .||. | |. . |...|||||. |.|.| || .| ||||| .| ||.||||.|. |. | | FDEERARFYAAEMQKICGCIVLALEYLHSHMGIIH-RDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHW-HNKKYQKSNMDTNKCNP -------------------SVAKSCKG--TFVYMAPEVLLTEGTYGLAADVWS--LGCTVIEMACGKPPWSGFGV---------RSLTFTSMRDG----- ... | | |||||.| || |.| || ||| || .|.|| .| . . .| . ..| NNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFIN CSPPIP----------PKMSTEAVSFIKLCLTRDPRRRPS----------AAALLSHPFF . ...| ...| ||...|| .|..||..|. | . .||.| WKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Pkinase | STE11-p2_j.AA | Pkinase | 1-179 | 33 | 4.4e-57 | 200.74 | Pfam | 82-293 (293) | Show / Hide |
Range on Protein: 1-179 Range on HMM: 82-293/293 Sequence Identity: 33% (72 aa) MKC-----SLASVIK--ESNGL--DESKLRVYTRQILSGLEYLHRMNIVHSRDVKCGNILLDPNGKA----KLADFGLAKKHRSHQIDYSVAKSCKGTFV . . .|...|. ..... .| .. | .|||.||||.|.|.|.| ||.| |||.| || |..||||||... .| ... || CEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIH-RDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPW YMAPEVLLTEGTYGLAADVWSLGCTVIEMACGKPPWSGF----GVRSLTFTSMRDGCSPPIPP----------------------KMSTEAVSFIKLCLT ||||||... || ..|.||.||...||.||.||..| . .. . |... |. . ..| |. .||| ||. YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC RDPRRRPSAAALLSHPFF .|| .||.|. .| ||.| KDPKKRPTAEQILQHPWF |
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Kinase | STE11-p2_j.AA | CAMK | 8-179 | 25 | 4.8e-51 | 162.32 | In-house | 170-425 (425) | Show / Hide |
Range on Protein: 8-179 Range on HMM: 170-425/425 Sequence Identity: 25% (65 aa) VIKESNGLDESKLRVYTRQILSGLEYLHRMNIVHSRDVKCGNILLDPN-----------------GKAKLADFGLAKKHRSHQ----------------- .. |. ..|. | | |||.|...|.| .|||| || |. ||||| | .. |..|||.|.| .. . IV-ERGRFTEREARRYFRQICSAVHYCHSHNIVH-RDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQW ---IDYSVAKSCKGTFVYMA-PEVLLT-------------EGTYGLAADVWSLGCTVIEMACGKPPWSGFG------------VRSLTFTSMRDGCSPPI .. | . || ||| ||||. . || ..|.||.|. | ||.||. | . .| . | . TTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFP PPKMST-----------------------EAVSFIKLCLTRDPRRRPSAAALLSHPFF ||..|. |. ..|. .|..|| .|.... |.||.. PPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | STE11-p2_j.AA | CAMKL | 25-179 | 31 | 8.6e-50 | 157.0 | In-house | 134-297 (297) | Show / Hide |
Range on Protein: 25-179 Range on HMM: 134-297/297 Sequence Identity: 31% (53 aa) RQILSGLEYLHRMNIVHSRDVKCGNILLDPNG--KAKLADFGLAKKHRSH-QIDYSVAKSCKGTFVYMAPEVLLT--EGTYGLAADVWSLGCTVIEMACG |||.|...|.|...||| || | ||||| || ..|..|||.. ..| . .. | . |. |||||... . .| ..|.||.| . | || RQIVSAVNYCHSHGIVH-RDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCG KPPWSGF--------GVRSLTFTSMRDGCSPPIPPKMSTEAVSFIKLCLTRDPRRRPSAAALLSHPFF . |. . . | |.. . |||....| .. ..|. |...| .||.. ...||.. YLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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Kinase | STE11-p2_j.AA | MEKK15 | 4-179 | 43 | 1.3e-48 | 167.87 | In-house | 87-264 (264) | Show / Hide |
Range on Protein: 4-179 Range on HMM: 87-264/264 Sequence Identity: 43% (78 aa) SLASVIKESNGLDESKLRVYTRQILSGLEYLHRMNIVHSRDVKCGNILLDPNGKAKLADFGLAKKHRSHQIDYSV---AKSCKGTFVYMAPEVLLTEGTY |..|.| ||| ||.||| | .||| ..|| ||.| |..| | | || ||| ||. |. . || .|| .|||||. | | SISSIINRFGPLDEMVFCKYTKQILQGVQYLHENCVVH-RDIKGNNVMLMPTGIIKLIDFGCAKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIMETG-Y GLAADVWSLGCTVIEMACGKPPWSGFGVRSLTFTSMRD-GCSPPIPPKMSTEAVSFIKLCLTRDPRRRPSAAALLSHPFF | .|.||.|||| ||| .|||| | . |..| | | .| |...||||| ||.| || ||| GRKSDIWSIGCTVFEMATRKPPWADMDRMAAMFYIGAHRDPMPQLPVKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI |
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Kinase | STE11-p2_j.AA | STE20 | 4-179 | 35 | 2.6e-46 | 160.17 | In-house | 94-288 (288) | Show / Hide |
Range on Protein: 4-179 Range on HMM: 94-288/288 Sequence Identity: 35% (70 aa) SLASVIK---ESNG------LDESKLRVYTRQILSGLEYLHRMNIVHSRDVKCGNILLDPNGKAKLADFGLAKKHRSH-QIDYSVA---KSCKGTFVYMA || ..| . .. ..|. . .|..| ||.|||...|.| ||.| .||||. .|..||||||.. . .| | . . .. || .|| SLTDIMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIH-RDIKADNILLTEDGEVKLADFGVCAQLTKHGR-D-TMQFKRNTFVGTPYWMA PEVLLT----EGTYGLAADVWSLGCTVIEMACGKPPWSGFGVRSLTFTSMRDGCSPP---I--PPKMSTEAVSFIKLCLTRDPRRRPSAAALLSHPFF |||.. .. |. .|.|||| | |||| |.|| . . . |. . . || | | |.| |...||..|| ||.| ||.|||. PEVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI |
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Kinase | STE11-p2_j.AA | STE-Unique | 4-179 | 30 | 1.4e-43 | 151.06 | In-house | 380-616 (616) | Show / Hide |
Range on Protein: 4-179 Range on HMM: 380-616/616 Sequence Identity: 30% (73 aa) SLASVIKESNG---------LDESKLRVYTRQILSGLEYLHRMN--IVHSRDVKCGNILLDPNG-----KAKLADFGLAKKHRSH--------------- .| ||.. . . |. ||.||| |||||| |.| ||.| .||... | |.|..|||.|.. TLQQIIKRCGCPGNPNNLQLFPETEVIWYTYQILEGLEYLHSQHNPIIH-RDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEKDNNSKNSNTWI --------------------QIDYSVAKSCKGTFVYMAPEVLLTE----GTYGLAADVWSLGCTVIEMACGKPPWSGFGVR-SLTFTSMRDGCSPP---- |. . |.| || ||.|||.... |.. .|.|||||....|.|| |||. .... .. . | || NINNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPEVINCRNQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQRYHMQAYIEMCIHIHCQPPQCPI --IPPKMSTEAVSFIKLCLTRDPRRRPSAAALLSHPFF |||| . | . || .|| |.| ||||. || |.. ENIPPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL |
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Kinase | STE11-p2_j.AA | MEKK2 | 15-179 | 44 | 1.5e-43 | 151.0 | In-house | 100-262 (262) | Show / Hide |
Range on Protein: 15-179 Range on HMM: 100-262/262 Sequence Identity: 44% (73 aa) LDESKLRVYTRQILSGLEYLHRMNIVHSRDVKCGNILLDPNGKAKLADFGLAKKHRSHQIDYSVAKSCKGTFVYMAPEVLLTEGTYGLAADVWSLGCTVI | |. | |||||| |..||| ||| ||.| ||| | | ||.||| .|. . || || .|.|||. || || |||||.||||. LTETVTRKYTRQILEGMHYLHDHMIVH-RDIKGANILRDSSGNVKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVINGEG-YGRKADVWSIGCTVV EMACGKPPWSGFGVRSLTFTSMRDGCSPPIPPKMSTEAVSFIKLCLTRDPRRRPSAAALLSHPFF || |||| . | | .|...| .| |.|.| . ||||. || | | EMLTEKPPWAEYEAMAAIFKIATQPTNPQLPQHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV |
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S_TKc | STE11-p2_j.AA | S_TKc | 1-179 | 25 | 1.6e-29 | 105.31 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1-179 Range on HMM: 1-231/231 Sequence Identity: 25% (67 aa) MK--------------------------------------------------------------------C---SLASVIKESNG------LDESKLRVY . .| ..||. .. ..| | | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY TRQILSGLEYLHRMNIVHSRDVKCGNILLDPNGKAKLADFGLAKKHRSHQIDYSVAKSCKGTFVYMAPEVLLTEGTYGL-AADVWSLGCTVIEMACGKPP ..||...|||.|...|.| ||.| ||||| |..|||||.. ... || ||||||| || ..|.||.||...||.||.|| MYQICCALEYCHSHGIIH-RDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPP WSGFGVRSLTFTSMRDGCSPPIPPKMSTEAVSFIKLCLTRDPRRRPSAAALLS-------HPFF .. ..| .. | || .||. ||..||..||.| .| ||.| FP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | STE11-p2_j.AA | Pkinase_Tyr | 11-179 | 28 | 2.3e-20 | 69.58 | Pfam | 104-270 (270) | Show / Hide |
Range on Protein: 11-179 Range on HMM: 104-270/270 Sequence Identity: 28% (49 aa) ESNGLDESKLRVYTRQILSGLEYLHRMNIVHSRDVKCGNILLDPNGKAKLADFGLAKKHRSHQIDYS--VAKSCKGTFVYMAPEVLLTEGTYGLAADVWS . . |. . | . .|| .|.|||...|..| ||. . |.|.. |...| .|||||. . . || .....| ||||.. . . . |||| DKQPLTMKDLLQMCWQIAKGMEYLESKNCIH-RDLAARNCLVTENNVVKICDFGLARDI--YNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWS LGCTVIEMAC-GKPP-WSGFGVRSLTFTSM-RDGCSPPIPPKMSTEAVSFIKLCLTRDPRRRPSAAALLSHPFF | . |. |. | . | . . .||. |.|.. . | . .|.| || .||. ... | .. FGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL |
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TyrKc | STE11-p2_j.AA | TyrKc | 1-179 | 18 | 4.3e-11 | -43.26 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 1-179 Range on HMM: 1-280/280 Sequence Identity: 18% (52 aa) MK------------------------------------------CSL-----------ASVIKE---------------------------SNG--LDES . |.| . .... ... | . ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK KLRVYTRQILSGLEYLHRMNIVHSRDVKCGNILLDPNGKAKLADFGLAKKHRSH------QIDYSVAK--SCK--GTFVYMAPEVLLTEGTYGLAADVWS .| . || .| ||||..|..| || . |.|.. |. .| .||||.... .. . |.... ..| ||||.. .|.. . |||| DLLSFCWQIACGMEYLHSKNCIH-RDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSDVWS LGCTVIEMA-CGKPPWSG-----FGVRSLTFTSMRDGCSPPIPPK--------MSTEAVSFIKLCLTRDPRRRPSAAALLSHPFF | . |. |..|..| . . . ..| .|.|| ...| . .| | .|| ||. ... | .| FGVCMWEIFTYGQQPYPGMIQQMMSNQEV-IEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |