Gene STE-p1_a-2 (S.moellendorffii)

STE-p1_a-2

Species: S.moellendorffii
Alias: STE-p1_a-2
External Links:
Annotation:

Classification

Group: STE
Family: STE-plant1

Sequence

Name Sequence Type Origin Length Description Download
STE-p1_a-2.AA Protein None 385 None Fasta, JSON
STE-p1_a-2.NA RNA None 1158 None Fasta, JSON
STE-p1_a-2.kin_dom Protein Kinase Domain None 262 None Fasta, JSON

Protein domain

Protein domains of STE-p1_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase STE-p1_a-2.AA STE 51-312 29 1.3e-95 323.91 In-house 1-359 (359) Show / Hide 
Range on Protein: 51-312
Range on HMM: 1-359/359
Sequence Identity: 29% (107 aa)

LERLEILGHGSGGKVYKARHRI---------------TGTLYALKIIQEKHD----------------PAVRKLIVREIEITRRFS-ARSPYVVQCYGVF
.|..|..|.|..|.||||...                ||...| |..  ...                .  .. | .||.| ....   .|..|..|| .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGCY

ERGG-------EISLVLEFMDGGTLANVLAAR--------------KTIDERFLARVTRQALKG-LMYLHANKIVHRDIKPSNLLLNRKNEVKIADFGVS
...|       |. ...|.||||.|  ..  .              ....|  .|...|| ||| | ||| ..|.||||||.| ||     ||..||||.
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

TQLAHTLA----------------QCNSFVGTCAYMSPERFDPDGHG--GHYDSSADIWSLGLTLLECAIGYFPC---VAPGQKPDWP--T-------LV
.||....|                ..|.||||  .|.||. ...|.|  ..|| ..||||||.|..| | |  |.     .     .|  .       ..
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

WAICLGDPPSPPPDAS-------------------PEFKSFIRSCLQKNSSQRPSAARLLH--HPFL
 .|  |.||. |.. |                   |||| ||. ||||. ..||.|  ||.  |||.
-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase STE-p1_a-2.AA STE7 51-312 36 1.7e-93 316.96 In-house 1-288 (288) Show / Hide 
Range on Protein: 51-312
Range on HMM: 1-288/288
Sequence Identity: 36% (107 aa)

LERLEILGHGSGGKVYKARHRITGTLYALKIIQEKHD-PAVRKLIVREIEITRRFSARSPYVVQCYGVFERGGE--ISLVLEFMDGGTLANVL--AAR--
||... ||||..| |||.||. .|...|.| |    . |. .| |..|... ....  .||.||.|| | . |.  |....|.||||.| ...  . .  
LEHIGELGHGNYGVVYKMRHKPSGKIMAVKRIRLTNNDPEEQKQILMELDVLHKCN-DCPYIVQFYGAFYTEGDDCIWICMEYMDGGCLDKFYKRVKKVY

-----KTIDERFLARVTRQALKGLMYLHA-NKIVHRDIKPSNLLLNRKNEVKIADFGVSTQLAHTLAQCNSFVGTCAYMSPERFDPDGHGGHYDSSADIW
     ..| |..|.... . .||| |||   || |||.|||| |.|.. .||..|||.. || ... . ..|||. .||.||| |.  .  |||  .|.|
RGIKKGRIPEQILGKIAVAVIKGLHYLHEKHKIIHRDVKPSNILVNSRGQVKLCDFGICGQLVDSMDAATTFVGCQPYMAPERIDG--NKQHYDVRSDVW

SLGLTL-LECAIGYFPCV-----APGQKP----------DWPTLVWAICLG-DPPSPPPDASPEFKSFIRSCLQKNSSQRPSAARLLH-HPFL
|||.|. .|.|.| .|.      .| ||            .  | . |  . .||  |   ||||..|.  ||||. . ||.  .|.. |||.
SLGITMGIEMATGRYPYPNWNTHPPDQKQYNNMFQPEMAIFEQLTC-IVNENPPPRLP-KFSPEFQDFVNKCLQKDPNERPKYHQLMKEHPFI
Kinase STE-p1_a-2.AA S_TKc 51-312 32 4.5e-93 316.43 SMART 1-231 (231) Show / Hide 
Range on Protein: 51-312
Range on HMM: 1-231/231
Sequence Identity: 32% (90 aa)

LERLEILGHGSGGKVYKARHRITGTLYALKIIQEKHDPAVRKLIVREIEITRRFSARSPYVVQCYGVFERGGEISLVLEFMDG--GTLANVLAARKT---
 | |...|.|. |||||.||. || ..|.|||         . | |||.| ..   . |..|..|.||.  ... .|.|..||  |.|  ..  |..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK---HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IDERFLARVTRQALKGLMYLHANKIVHRDIKPSNLLLNRKNEVKIADFGVSTQLAHTLAQCNSFVGTCAYMSPERFDPDGHGGHYDS-SADIWSLGL
   ..|   .....| ...| |.| ..|.|||.||.|.||..  ..||.|||...||       ..|.||  ||.|| .       .|.  ..|.||.| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGC

TLLECAIGYFPCVAPGQKPDWPTLVWAICLGDPPSPPPDASPEFKSFIRSCLQKNSSQRPSAARLLH-------HPFL
.| |.. || |        .  ..   |.           |||.|.||| ||||. ..||.|  .|.       ||..
ILYEMLCGYPPFP------QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase STE-p1_a-2.AA STE7-Unclassified 51-312 34 4.6e-89 302.2 In-house 1-301 (301) Show / Hide 
Range on Protein: 51-312
Range on HMM: 1-301/301
Sequence Identity: 34% (103 aa)

LERLEILGHGSGGKVYKARHRI------TGTLYALKIIQ-EKHDPAVRKLIVREIEITRRFSARSPYVVQCYGVFERGGE---ISLVLEFMDGGTLA---
||||..||||..|.|.|..|        .|. .|.| |  .  |.. .| |.||... . ..  .||.|..|| .   .    | ...|.||.|.|    
LERLKYLGHGMHGTVVKCLHKNGMVIARDGKIMAWKVIPTMDNDNEFMKQILRELKTLHKCQ-PHPYIVHYYGAYYHECMDCKIHICMEYMDCGSLDNKI

NVLAAR--------KTIDERFLARVTRQALKGLMYLHANK-IVHRDIKPSNLLLNRKNEVKIADFGVSTQLAHTLAQCNSFVGTCAYMSPERFDPD-GHG
 ..           ..|.|. |.... | ..|| |||  . |.||||||.|.|.| | .|||.||||. || .|| . ...||.  ||||||.  .  | 
DIYKKMYERGPIRGGWIPEPVLGKIAYQVIHGLWYLHEKHHIIHRDIKPGNILVNSKGQVKICDFGVCGQLENTLDEAKTWVGCQMYMSPERIQGQMPHR

GHYDSSADIWSLGLTLLECAIGYFPC---VAPGQKPDWPT------LVWAICLGDPPSPPPDA-------SPEFKSFIRSCLQKNSSQRPSAARLLH-HP
  |    ||||||||..|||.| .|.     . |. . .       ..   |  ..|.|. .        |.||..||  |..|..  ||... ||. ||
PSYSVKSDIWSLGLTIWECATGKYPYEYNFQSEQYNQNFQPENMSFWELLSCIVNFPVPRLPDDPEDIIWSKEFMDFISKCCKKHPRERPDIHQLLNEHP

FL
..
WI
Kinase STE-p1_a-2.AA Pkinase 51-312 28 1.2e-77 269.07 Pfam 1-293 (293) Show / Hide 
Range on Protein: 51-312
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

LERLEILGHGSGGKVYKARHRITGTLYALKIIQEKHDPA-VRKLIVR--EIEITRRFSARSPYVVQCYGVFERGGEISLVLEFMDGG----TLANVLA--
.......| || |.|||..|. || ..|.|||  .|.   ...  .|  ||.| .|..  .|..|..|..||....| .|.|...||     |. ..   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN--HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

ARKTI--DERFLARVTRQALKGLMYLHANKIVHRDIKPSNLLLNRKNEV----KIADFGVSTQL-AHTLAQCNSFVGTCAYMSPERFDPDGHGGHYDSSA
.....  .|. . .. .| |.|| |.|...|.|||.||.|.|.......    ||.|||.. |.       ...|.||  ||.||      .| .|....
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GGQYYGPKV

DIWSLGLTLLECAIGYFPCVAPGQKPDWPTLVWAICLGDPPSPPPDAS-----------------------PEFKSFIRSCLQKNSSQRPSAARLLHHPF
|.||.|..| | . |..|.   .. ..  .  . ||.  .| .. | .                       .|.|.||..||.|. ..||.|. .|.||.
DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

L
.
F
Kinase STE-p1_a-2.AA MEK1 51-259 48 2.6e-67 229.02 In-house 1-202 (297) Show / Hide 
Range on Protein: 51-259
Range on HMM: 1-202/297
Sequence Identity: 48% (102 aa)

LERLEILGHGSGGKVYKARHRITGTLYALKIIQEKHDPAVRKLIVREIEITRRFSARSPYVVQCYGVFERGGEISLVLEFMDGGTLANVLAARKTIDERF
.|... |||| || | |.||| || . | |.|.    ||.|. |.||...  .    |||.|  || |   ||||. .|.|||| |  ||   . | |..
FEKIGELGHGNGGVVMKCRHRHTGMIMARKLIHLEIKPAIRNQIIRELQVLHE--CNSPYIVGFYGAFYSDGEISICMEYMDGGSLDQVLKKAGRIPEKI

LARVTRQALKGLMYLHAN-KIVHRDIKPSNLLLNRKNEVKIADFGVSTQLAHTLAQCNSFVGTCAYMSPERFDPDGHGGHYDSSADIWSLGLTLLECAIG
| .|.   |.||.||. . ||.|||.||||.| | . |.|. ||||| ||   .|  |||||| .||||||      | ||  ..||||.|| | | |||
LGKVSVAVLRGLTYLRDKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMA--NSFVGTRSYMSPERL----QGTHYTVQSDIWSMGLSLVEMAIG

YFPCVAPGQK
 .|  .| ||
RYPIPPPDQK
Kinase STE-p1_a-2.AA CAMK 56-312 21 8.7e-64 204.13 In-house 1-425 (425) Show / Hide 
Range on Protein: 56-312
Range on HMM: 1-425/425
Sequence Identity: 21% (91 aa)

ILGHGSGGKVYKARHRITG------------TLYALKIIQ----------------------EKH-----DPAVRKLIVREIEITRRFS-----ARSPYV
.||.|| |||....|. |.            . .| |||                       .||     .|  || . ||||| .. .      . | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQCYGVFE------------RGGE--------ISLVL---EFMDGG----TLANVLAAR---------------KTIDERFLARVTRQALKGLMYLHANK
...| |.|                        . .|.   |...||     | . . ..               . ..||  .|. || . .. |.| ..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDIKPSNLLLNRK-----------------NEVKIADFGVSTQLAHTL-----------------------AQCNSFVGTCAYMS-PERFDPDGH--
|||||.|| |.||. .                 | .||.||| .... .                           .. |.|| .||. || .   ||  
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------GGHYDSSADIWSLGLTLLECAIGYFPCVAPGQKPDW---------PTLVWAICLGDPPSPPPDASP-----------------------EFK
           |. ..|.||.|  |  .  ||.|  .. .. .          . |   |. |.   |||  ||                       | |
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

SFIRSCLQKNSSQRPSAARLLHHPFL
..||..||.. ..|....  | ||..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase STE-p1_a-2.AA MEK5 51-312 39 1.3e-58 201.03 In-house 1-254 (254) Show / Hide 
Range on Protein: 51-312
Range on HMM: 1-254/254
Sequence Identity: 39% (105 aa)

LERLEILGHGSGGKVYKARHRITGTLYALKIIQEKHDPAVRKLIVREIEITRRFSARSPYVVQCYGVFERGGEISLVLEFMDGGTLANVLAARKTIDERF
.   . |||| || |||| |  .| . |.|.|       ..| |. |.||   .   |||..  || |     ||.  ||||||     |   . | |  
IRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEIL--YKCDSPYIIGFYGAFFVENRISICTEFMDGGS----LDMYRCIPEHI

LARVTRQALKGLMYLHANKIVHRDIKPSNLLLNRKNEVKIADFGVSTQLAHTLAQCNSFVGTCAYMSPERFDPDGHGGHYDSSADIWSLGLTLLECAIGY
| |.|    ||| ||   ||.|||.||||.| | . ..|. ||||||||   ...   ..|| ||| |||   |  | |    .|.||||. ..| |.| 
LGRMTVAIVKGLNYLWNLKIMHRDVKPSNMLVNTQGQIKLCDFGVSTQLVNSITRT--YIGTNAYMAPERISGDQYGIH----SDVWSLGIFFMEMATGR

FPCVAPGQKP---DWPTLVWAICLGDPPSPPPDA-SPEFKSFIRSCLQKNSSQRPSAARLLHHPFL
||  .  .         |.  |   .||  | |  |  |  ||  |.||   .||    |. |||.
FPYPQIQRDQGELMPIQLLQCIVDEHPPRLPVDKFSEPFVHFINQCMQKQPKDRPKPQDLMQHPFI
Kinase STE-p1_a-2.AA STE20 51-245 36 5.9e-57 195.53 In-house 1-219 (288) Show / Hide 
Range on Protein: 51-245
Range on HMM: 1-219/288
Sequence Identity: 36% (80 aa)

LERLEILGHGSGGKVYKARHRITGTL----YALKIIQEKHDP---AVRKLIVREIEITRRFSARSPYVVQCYGVFERG----GEISLVLEFMDGGTLANV
 | || .|.|| ||||||.|. || .    .| |..  ...      ...|. || | ...   .|..|. || . ..     |. .| |...||.|  .
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK--HPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDI

LA---ARK------TIDERFLARVTRQALKGLMYLHANKIVHRDIKPSNLLLNRKNEVKIADFGVSTQLAH----TLA-QCNSFVGTCAYMSPERFDP-D
.     ..      ...|   | ..|..|.|| |||.|.|.|||||  | ||. . |||.|||||. || .    | . . |.||||  .|.||     .
MKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCME

GHGGHYDSSADIWSLGLTLLE
|  . ||. .|||||| |..|
GPDKGYDYKCDIWSLGITAIE
Kinase STE-p1_a-2.AA TKL 57-310 18 2.1e-53 183.72 In-house 1-364 (364) Show / Hide 
Range on Protein: 57-310
Range on HMM: 1-364/364
Sequence Identity: 18% (70 aa)

LGHGSGGKVYKARHRI--------TGTLYALKIIQEKH-----------------------DPAVRKLIVREIEITRRFS-ARSPYVVQCYGVFERGGE-
.| |. |.|||...|         ||.  | |.. ...                       ||  ...  .|.| ..  |  | | .||..|.  ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------ISLVLEFMDGGTLANVLAARKTIDERFLARVTRQALKGLMYLHANK--------IVHRDIKPSNLLLNRKNE--------------VK
            . .| |...||.| ..|          . |  ... .|. |||...        |.|||.|..|.|......              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

IADFGVSTQLAHTLAQCNS-------------------FVGTCAYMSPERFDPDG------------HGGHYDSSADIWSLGLTLLECAIGYFPCVAPGQ
|.||| |. . ..  .  .                    .|| ..|.|| .. ..            .|. |. ..|..| |. | |.. .      | .
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR----PYY

KPDWPTLV---------WAICLGD-PPSPP------------PDASPEFKSFIRSCLQKNSSQRPSAARLLHHP
... .. .         . .|.   .| .|            ||. |..|. .  | . . ..|||. ..|.. 
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase STE-p1_a-2.AA KHS 52-247 36 9.5e-45 148.36 In-house 2-193 (258) Show / Hide 
Range on Protein: 52-247
Range on HMM: 2-193/258
Sequence Identity: 36% (72 aa)

ERLEILGHGSGGKVYKARHRITGTLYALKIIQEKHDPAVRKLIVREIEITRRFSARSPYVVQCYGVFERGGEISLVLEFMDGGTLANVLAARKTIDERFL
| |  .| |  | |||||.  ...| |.|.|.   .  . ..| .|| . .    | | .|  .| . |   . ...|.  || | ..  .   . |. .
ELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDF-AVIQQEIMMMKD--CRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGPLSELQI

ARVTRQALKGLMYLHANKIVHRDIKPSNLLLNRKNEVKIADFGVSTQLAHTLAQCNSFVGTCAYMSPERFDPDGHGGHYDSSADIWSLGLTLLECA
| |.|..|.|| |||... .|||||  |.||. . .||.||||||.|.. |.|.  ||.||  .| ||    . .|| |.   |||..|.| .| |
AYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGG-YNQLCDIWAVGITAIELA
Kinase STE-p1_a-2.AA MST 108-247 40 3.5e-39 122.15 In-house 53-191 (254) Show / Hide 
Range on Protein: 108-247
Range on HMM: 53-191/254
Sequence Identity: 40% (58 aa)

SPYVVQCYGVFE--RGGEISLVLEFMDGGTLANVL-AARKTIDERFLARVTRQALKGLMYLHANKIVHRDIKPSNLLLNRKNEVKIADFGVSTQLAHTLA
|.|.|. || .      .. .| |. ..| .. .  . ..|  |   | . ...|.|| ||| ||..|||||. | ||| . | | |||||| || .| |
SKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMA

QCNSFVGTCAYMSPERFDPDGHGGHYDSSADIWSLGLTLLECA
  |...||  .|.||     .    ||. ||||||| | .| |
KRNTVIGTPYWMAPEVIQEIK----YDCKADIWSLGITAIEMA
Kinase STE-p1_a-2.AA Pkinase_Tyr 51-196 28 3.1e-19 65.75 Pfam 1-158 (270) Show / Hide 
Range on Protein: 51-196
Range on HMM: 1-158/270
Sequence Identity: 28% (46 aa)

LERLEILGHGSGGKVYKARHR----ITGTLYALKIIQEKHDPAV--RKLIVREIEITRRFSARSPYVVQCYGVFE-RGGE--ISLVLEFMDGGTLANVLA
.. .. ||.|. |.|||.. .     |..  | |.. |....    |.   ||..| . .  . | .|..|||   .|.   | .|.|.| .| | . | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQL-GHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

A----RKTIDERFLARVTRQALKGLMYLHANKIVHRDIKPSNLLLNRKNEVKIADFGVS
.    .. ..   |    .|  ||. ||......|||.   | |....| |||.||| .
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase STE-p1_a-2.AA TyrKc 51-312 20 4.6e-16 36.96 SMART 1-280 (280) Show / Hide 
Range on Protein: 51-312
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

LERLEILGHGSGGKVYKARHRITGTLYALKIIQEKHDPAVRKLIVREIEITRRF--SARSPYVVQCYGVFERG-------GEISLVLEFMDGGTLANVL-
.. ...||.|  |.|||.. .   .  | | ..| .    |. . ||..| ...  .   | .|..|||   .       . . .|.|.|..| | . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHH--PNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

AARKTIDERFLARVTRQALKGLMYLHANKIVHRDIKPSNLLLNRKNEVKIADFGVSTQLAHT--------LAQC----NS-FVGTCAYMSPERFDPDGHG
. |...  . |     |. .|  ||| ....|||.   | |..... |||.||| |  . .                 .. ..     |.|| .      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----NY

GHYDSSADIWSLGLTLLE----CAIGYFPCVAPGQKPDWPTLVWAICLGDPPSPPPD--------ASPEFKSFIRSCLQKNSSQRPSAARLLHHPFL
| . .  |.|| | .. |    ..  |   .    . ..  ..  .  |. . .||.        ...|  . ...| . . ..||. . .  | ..
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase STE-p1_a-2.AA MST 282-312 54 4.9e-15 44.16 In-house 224-254 (254) Show / Hide 
Range on Protein: 282-312
Range on HMM: 224-254/254
Sequence Identity: 54% (17 aa)

SPEFKSFIRSCLQKNSSQRPSAARLLHHPFL
|.||  |...|||||..||..| .|| ||| 
SQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase STE-p1_a-2.AA STE20 272-312 42 4.5e-14 48.08 In-house 242-288 (288) Show / Hide 
Range on Protein: 272-312
Range on HMM: 242-288/288
Sequence Identity: 42% (20 aa)

GDPPSP------PPDASPEFKSFIRSCLQKNSSQRPSAARLLHHPFL
...|.|      |   ||||. |. .||||. ..||.|  ||.|||.
NQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase STE-p1_a-2.AA KHS 282-312 45 5.2e-10 29.72 In-house 228-258 (258) Show / Hide 
Range on Protein: 282-312
Range on HMM: 228-258/258
Sequence Identity: 45% (14 aa)

SPEFKSFIRSCLQKNSSQRPSAARLLHHPFL
|. |  |.. .| ||. .||.| .||.|||.
SQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase STE-p1_a-2.AA MST 52-82 48 1.3e-08 23.41 In-house 2-32 (254) Show / Hide 
Range on Protein: 52-82
Range on HMM: 2-32/254
Sequence Identity: 48% (15 aa)

ERLEILGHGSGGKVYKARHRITGTLYALKII
. .|.|| || |.|||| |. || ..| |..
DIVEKLGQGSYGSVYKAIHKQTGKIVAIKMV
Kinase STE-p1_a-2.AA MEK1 282-312 38 3.3e-05 13.18 In-house 267-297 (297) Show / Hide 
Range on Protein: 282-312
Range on HMM: 267-297/297
Sequence Identity: 38% (12 aa)

SPEFKSFIRSCLQKNSSQRPSAARLLHHPFL
| ||. |.  ||.|| . |    .|. |.|.
SEEFQDFVDKCLIKNPDERADLKQLMVHTFI
Kinase STE-p1_a-2.AA Pkinase_Tyr 277-312 19 0.01374 9.39 Pfam 237-270 (270) Show / Hide 
Range on Protein: 277-312
Range on HMM: 237-270/270
Sequence Identity: 19% (7 aa)

PPPDASPEFKSFIRSCLQKNSSQRPSAARLLHHPFL
.|.....|  . ...| ... ..||. . .  | .|
CPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL