Gene TTK_a (S.moellendorffii)

TTK_a

Species: S.moellendorffii
Alias: TTK_a
External Links:
Annotation:

Classification

Group: Other
Family: TTK

Sequence

Name Sequence Type Origin Length Description Download
TTK_a.AA Protein None 418 None Fasta, JSON
TTK_a.NA RNA None 1257 None Fasta, JSON
TTK_a.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of TTK_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc TTK_a.AA S_TKc 53-336 24 3e-68 233.98 SMART 1-231 (231) Show / Hide 
Range on Protein: 53-336
Range on HMM: 1-231/231
Sequence Identity: 24% (74 aa)

YQKLGKIGSGGSSHVFKVIAQD-CTIYALKRIILKGRDHQTACGFHQEIEYLERLKGKNHIIQLIDYEVTDKTIFRSDSAAAHGEILNDVRIYMVLEYGE
|..| |||.|. . |.|..  .   |.|.|.|          . . .||. |..  .  .|..|.|. ..                    ..|||.|| .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-------------------DHLYMVMEYCD

I---DLARILERKKSEDGQ--LDENWLRLHWEHILKAVNTIHEERIVHADLKPANFLLVQGALKLIDFGIAKAIQNDTTNIVRESQVGTLNYMSPEAFLM
    || ......... ..  ..| . |     |..|.. .|. .|.| ||||.| || .  .|..|||.|. .          ...||..||.|| .  
GDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL---------TTFCGTPWYMAPEVL--

NSRDEQGTVKCGR-ASDIWSLGCILYQMVYGRTPFSHLSFYQKIREITNENHVINFPPVSNPLIVDVMKSCLMWDKDKRPRIPQLLE-------HAFL
         . |. ..|.||.||||| |..|..||.    .. .. |              |   | .. || .| .||| . ..|.       | ..
---------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase TTK_a.AA Pkinase 53-336 25 4.1e-61 214.14 Pfam 1-293 (293) Show / Hide 
Range on Protein: 53-336
Range on HMM: 1-293/293
Sequence Identity: 25% (85 aa)

YQKLGKIGSGGSSHVFKVIAQDCTI-YALKRIILKGRDHQT------ACGFHQEIEYLERLKGKNHIIQLIDYEVTDKTIFRSDSAAAHGEILNDVRIYM
|....|||||... |.| . ..  . .|.|.| .......       .    .||... ||. .| |..|.|.  .                  . .|||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL----SEIQIMKRLNHPN-IVRLYDWFED------------------KDHIYM

VLEYGEI-----DLARILERKKSEDGQL--DENWLRLHWEHILKAVNTIHEERIVHADLKPANFLLV-QGAL----KLIDFGIAKAIQNDTTNIVRESQV
|.|| |      ||......  ...| .  .|. ..  .  ||.... .|...|.| ||||.|.|.. .| .    |..|||.|| ..    |    . .
VMEYCEGGLYVMDLFDYIST--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFC

GTLNYMSPEAFLMNSRDEQGTVKCGRASDIWSLGCILYQMVYGRTPFSHL------SFYQKIREITNENHVINFPPVSN-------------------PL
||..||.||  .       |  . |...|.||.|||||.|. ||.||..       . .|.|..|       ..|  ..                   . 
GTPWYMAPEVIR-------GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEE

IVDVMKSCLMWDKDKRPRIPQLLEHAFL
  |..|.|| .|  ||| ..|.|.| ..
CKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase TTK_a.AA TTK 138-243 54 5.1e-61 200.6 In-house 70-177 (344) Show / Hide 
Range on Protein: 138-243
Range on HMM: 70-177/344
Sequence Identity: 54% (60 aa)

LN--DVRIYMVLEYGEIDLARILERKKSEDG--QLDENWLRLHWEHILKAVNTIHEERIVHADLKPANFLLVQGALKLIDFGIAKAIQN-DTTNIVRESQ
..  .  ||||.| |..||. .| ..|   .   |. . ..  |   | .|..||.. ||| |||||||..||| |||||||||.|||| ||||||.|||
MTMEEQYIYMVMECGDCDLNKWLQKYK---TPMNLNPWFMWCYWQQMLQCVHVIHQHGIVHSDLKPANFVMVQGMLKLIDFGIANAIQNDDTTNIVKESQ

VGTLNYMSPEA
.||.|||||||
IGTFNYMSPEA
Kinase TTK_a.AA CMGC 53-336 15 6.1e-41 131.65 In-house 1-513 (513) Show / Hide 
Range on Protein: 53-336
Range on HMM: 1-513/513
Sequence Identity: 15% (84 aa)

YQKLGKIGSGGSSHVFKVIAQDC---------------TIYALKRIILKGRDHQTAC------GFH----QEIEYLERLK----------------GKNH
|....|||.|  . |.| . ...                |.|.|.| ..  .. .|.      ||      ||..|..|.                 .|.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIQLIDYEVTDKT----------IFRSDSAAAHGEILNDVRIYMVLEYGEIDLARILERKKS-EDG----QLDENW------------LRLHW------E
|..|.|. .....          |  |        . ... .|.| || . ||........  . |     |.|               .          
IVKLYDIFYHKNSDGNEYEDKHII--S--------Q-HFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMY

HILKAVN--TIHEER--IVHADLKPANFLLVQ---------------------GALKLIDFGIAKAIQNDTTNI-------------------VRESQVG
 ||....   .|  .  |.| ||||.| |. .                     | ||..||| |... .   ..                      ..| 
QILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVV

TLNYMSPEAFLMN----SRDEQGTVKCGRASDIWSLGCILYQMVYG--------RTPFS--------------HLSFYQKIREITN--------------
|. | .||  |      .   . . . . . |.||.|||.. |. |        .. |               |.   .|| ..                
TRWYRAPEILLGWKHYTNH--NYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFN

----ENHVIN------------------------------------FPPVSN----------------------------------------------PL
    |.  .|                                    ||..                                                |.
FCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQ

IVDVMKSCLMWDKDKRPRIPQLLEHAFL
 .| .| .| .| |||. . | |.| ..
AIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase TTK_a.AA AGC 178-336 21 7.2e-39 96.89 In-house 154-395 (395) Show / Hide 
Range on Protein: 178-336
Range on HMM: 154-395/395
Sequence Identity: 21% (56 aa)

E------HILKAVNTIHE-ERIVHAD-LKPANFLLVQ-GALKLIDFGIAKAIQNDTTNIVRESQ------------------------------------
|      .|. |.  .|.   |.| | ||| | || . | .|| ||| .| . || .. .  ||                                    
EMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQ-SQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQED

-------------VG--TLNYMSPEAFLMNSRDEQGTVKCGRASDIWS--LGCILYQMVYGRTPFSHLS----------FYQKIREITNE----NHVINF
             .|  | .||.|| .            .|.| |.||  |||..|.|..|..||.. .           ...   | |     |. . |
DTTRKKRDRTWTFCGPCTPEYMAPEIL------------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKF

P----------PVSNPLIVDVMKSCLMWDKDKRPR----------IPQLLEHAFL
|          .   |  .| .| .|  | .||.           . .. .| . 
PFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase TTK_a.AA STE 53-336 19 1.4e-38 133.83 In-house 1-359 (359) Show / Hide 
Range on Protein: 53-336
Range on HMM: 1-359/359
Sequence Identity: 19% (75 aa)

YQKLGKIGSGGSSHVFKVIAQD-----CTI-----------YALKRIILKG---------------RDHQTACGFHQEIEYLERLKG-KNHIIQLIDYEV
.....|||.|..  |.| .  .     .|            .| |.. |.                ..|.    . .||. . ...    .|.. .....
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TDKTIFRSDSAAAHGEILNDV--RIYMVLEYGE-IDLARILERKKSEDGQLD----------ENWLRLHWEHILKA-VNTIHEERIVHADLKPANFLLVQ
 . .              ..    .....|| .   |  |...|..  ..|.          |....     |||.  . .|. .|.| |.|||| ||  
KEGHN-------------HKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--

GALKLIDFGIAKAIQND--------------TTNIVRESQVGTLNYMSPEAFLMNSRDEQGTVKCGRASDIWSLGCILYQMVYGRTPFSHLSFYQKIREI
   ||.|||... ....              |.   | . |||  .|.||  . |...     .... .||||||| .  |. |. |.. ..  . . .|
--VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R-DKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMI

TNENHVI-----------NFPPVSN----------------------PLIVDVMKSCLMWDKDKRPRIPQLLE--HAFL
....|.            . ||  .                      |   | .. ||  | .|||   |||.  | |.
PFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase TTK_a.AA ULK 143-336 26 1.1e-37 129.13 In-house 95-329 (329) Show / Hide 
Range on Protein: 143-336
Range on HMM: 95-329/329
Sequence Identity: 26% (64 aa)

IYMVLEYGEI-DLARILERKKS------EDGQLDENWLRLHWEHILKAVNTIHEERIVHADLKPANFLLVQG-------------ALKLIDFGIAKAIQN
||...|| .  ||  .....|       | . | |.  .    .|| .   .|...|.| |.||.| |.  |              ||. ||| || ..|
IYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDN

D-TTNIVRESQV------GTLNYMSPEAFLMN-SRDEQGTVKCGRASDIWSLGCILYQMVYGRTP----FSHLSFYQKIREITN--------ENHVINFP
|   . .  ..|      ||  ||.|. .  .  . .... ||    ||||||||.|.|.||..|    |. .  ......| |        ... ..||
DNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKC----DIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFP

-----PVSNPLIVDVMKSCLMWDKDKRPRIPQLLEHAFL
     |.  | . |  . .|  | ..|  ...|..| ..
KDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase TTK_a.AA Ciliate-E2 178-336 22 2.1e-35 119.0 In-house 152-365 (365) Show / Hide 
Range on Protein: 178-336
Range on HMM: 152-365/365
Sequence Identity: 22% (52 aa)

EHILK---------------AVNTIHEER-IVHADLKPANFLLVQGALKLIDFGIAKAIQNDTT--------NIVRESQ---------------------
..||.               |.. .|..  |.| |.|| | |.    .|.||||..| ...|          ..  . .                     
KQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNT

-VGTLNYMSPEAFLMNSRDEQGTVK-CGRASDIWSLGCILYQMVYGRTPFSHLSFYQKIREITNENHVINFPPVSNPLI------------------VDV
 .||..||.|| . . . | | . |  . ..||||||.|||.|..|..||          .. ...  |.||.  . .                    | 
ICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDL

MKS----CLMWDKDKRPR-IPQLLEHAFL
.|     .|  | .||.  . |.|.| ..
IKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase TTK_a.AA TTK 255-336 42 2.9e-35 114.01 In-house 256-344 (344) Show / Hide 
Range on Protein: 255-336
Range on HMM: 256-344/344
Sequence Identity: 42% (38 aa)

VKCGRASDIWSLGCILYQMVYGRTPFSHLSFYQ-KIREITNENHVINFPPVS------NPLIVDVMKSCLMWDKDKRPRIPQLLEHAFL
.| ...||.||.|||||.|.||.||| | .    |   |.| .| | ||. .      | . ..||| ||  . .||. || || | |.
WKISCKSDVWSCGCILYYMIYGKTPFQHIQNQYSKMHAICNPHHKIEFPEHPPYYEKINKMLIHVMKCCLYRNPKKRWSIPELLNHPFH
Kinase TTK_a.AA ULK 143-336 26 7.5e-35 121.12 In-house 92-324 (324) Show / Hide 
Range on Protein: 143-336
Range on HMM: 92-324/324
Sequence Identity: 26% (63 aa)

IYMVLEYGEI-DLARILERKKS-----EDGQLDENWLRLHWEHILKAVNTIHEERIVHADLKPANFLLVQG-------------ALKLIDFGIAKAIQND
||...|| .  ||  .....|      | . | |.  .    .|. .   .|.. |.| |.||.| |.  |              ||. ||| || ..|.
IYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNN

-TTNIVRESQV------GTLNYMSPEAFLMN-SRDEQGTVKCGRASDIWSLGCILYQMVYGRTPFSHLSFYQKI----REIT--------NENHVINFP-
     .. ..|      ||  ||.|. .  .  . .... ||    ||||||||.|.|.||..||.   |.. .    ..|          .|  |.|| 
NMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKC----DIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPK

----PVSNPLIVDVMKSCLMWDKDKRPRIPQLLEHAFL
    |.  | . |  . .|  | ..|  ......| ..
PPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase TTK_a.AA Ciliate-E2-Unclassified 143-336 21 1e-34 117.86 In-house 96-352 (352) Show / Hide 
Range on Protein: 143-336
Range on HMM: 96-352/352
Sequence Identity: 21% (57 aa)

IYMVLEYGEIDLARILERKKSE--------------DGQLDENWLR-----LHWEHILKAVNTIHEE-RIVHADLKPANFLLVQG----ALKLIDFGIAK
||.|.|| |    .   .|..               . ...|.  .         .||.. . .|..  |.| |.|| | |. ..     .|.|||||.|
IYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISK

AIQNDTTNIVRE--------------SQVGTLNYM----SPEAFLMNSRDEQGTVKCGRASDIWSLGCILYQMVYGRTPFSHLSFYQ-------------
 .|..  .   .              ...||.|||    .|| .  .  |..       ..||||||.|||.|..|. ||.  . .|             
KYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA----YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAY

--KIREITNENHV-----------INFPPVSNPLIVDVMKSCLMWDKDKRPRIPQLLEHAFL
   .... ... .            . .|    .| | ....| .. .||. ..|.|.| ..
RKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase TTK_a.AA CAMK 58-336 19 4.1e-34 106.79 In-house 1-425 (425) Show / Hide 
Range on Protein: 58-336
Range on HMM: 1-425/425
Sequence Identity: 19% (83 aa)

KIGSGGSSHVFKVIAQ-DC------------TIYALKRIILKG--------------RDHQTACG------------FHQEIEYLERLKGKN------HI
..|.|. . |...|   .             . .| | |  |               .|......            . .||| . .|.|..      .|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IQLIDYEVTDKTIFRSDSAAAHGEILNDV------RIYMVL---EYG---EI--D-LARILER-----------KKSEDGQLDENWLRLHWEHILKAVNT
|.|...  ... .     .   .|  ...      ..|||.   ||    |   | . .| |.              |.| ..|   |     |. ||. 
IKLYEVYEDPHYFK-N--TND-YET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHY

IHEERIVHADLKPANFLLVQ------------------GALKLIDFGIAKAIQND---------------------TTNIVRESQVGTLNYMS-PEAFLM
.|.  ||| |||| | ||..                  . .|.|||| |. .. .                     |..   . ..||. ||. || .. 
CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG

NSRDEQG------TVKCGRASDIWSLGCILYQMVYGRTPFSHL-------------SFYQKIREITNENHVINFPPVSN---------------------
..... .         .|...|.||.|.||| |. |. || .              . |.  . |.. .     |..|.                     
KGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFV

-PLIVDVMKSCLMWDKDKRPRIPQLLEHAFL
 .   |  ...|  | .||. | | |.| ..
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase TTK_a.AA STE11 188-336 28 3.2e-26 91.98 In-house 133-303 (303) Show / Hide 
Range on Protein: 188-336
Range on HMM: 133-303/303
Sequence Identity: 28% (50 aa)

HEERIVHADLKPANFLLVQ-GA-LKLIDFGIAKAIQNDTTNIVRESQ--------VGTLN--------YMSPEAFLMNSRDEQGTVK-CGRASDIWSLGC
|. .|.| |.|.|| || . |  .||.|||.|| .....|.    ..         ||..        .|.||         |.. .  ||..|||||||
HSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPMWMAPEVI------KQEGRDGYGRKADIWSLGC

ILYQMVYGRTPFSHLSF--YQKIREITNE-NHVINFPP-VSN-----PLIVDVMKSCLMWDKDKRPRIPQLLEHAFL
. . |. |. |.. ...  .. .  |    .  ...|  .|      .   |  . |.  |. |||   |||.| |.
TVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase TTK_a.AA TTK 53-126 43 1.4e-25 81.45 In-house 1-78 (344) Show / Hide 
Range on Protein: 53-126
Range on HMM: 1-78/344
Sequence Identity: 43% (34 aa)

YQKLGKIGSGGSSHVFKVIAQ-DCTIYALKRIILKGRDHQTACGFHQEIEYLERLKGKN-HIIQLIDYEVT--DKTIF
| .. .||.|||| ||.|    .  |||||.  |   | ||  |.  |||.|..|..    ||||.|||.|  .  |.
YSIIKQIGCGGSSKVFQVLSEDSKKIYALKYVCLDFADPQTIQGYMNEIEMLNKLQQQKDCIIQLYDYEMTMEEQYIY
Kinase TTK_a.AA TyrKc 53-334 17 1.6e-08 -84.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 53-334
Range on HMM: 1-280/280
Sequence Identity: 17% (55 aa)

YQKLGKIGSGGSSHVFKVIAQDCTIYALKRIILKGRDHQTACGFHQEIEYLERL-KGKNHIIQLIDYEVTDKTIFRSDSAAAHGEILNDVRIYMVLEYGE
 ... |.|.|    |.| ..   .  | | .            |..|.. . .| .   .|..|. . ....              . .  ...|.|| .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-----------FMYIEPLMIVMEYMP

-IDLARILERKKSEDGQLDENWLRLHW--EHILKAVNTIHEERIVHADLKPANFLLVQGA-LKLIDFGIAKAIQND-------TTNIV----RESQVGTL
  ||   | ... .      ..  |.     | .  . .|. ...| ||   | |.  .   |  ||| ...| .|        .  .     .  .  .
HGDLKDYLRKHRPK-----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI

NYMSPEAFLMNSRDEQGTVKCGRASDIWSLGCILYQMV-YGRTPFSH-----LSFYQKIREITNENHVINFPPV--------SNPLIVDVMKSCLMWDKD
  |.||..         . |.  .||.|| |  .. .  || .| .      .| .. ..|   . .    ||           . . ..||.| . | .
RWMAPECI--------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQE-VIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPE

KRPRIPQLLEHA
.||.  .. |  
DRPTFSEIHECF
Kinase TTK_a.AA Pkinase_Tyr 213-336 24 6.1e-05 17.37 Pfam 154-270 (270) Show / Hide 
Range on Protein: 213-336
Range on HMM: 154-270/270
Sequence Identity: 24% (31 aa)

DFGIAKAIQNDTTN-IVRESQVGTLNYMSPEAFLMNSRDEQGTVKCGRASDIWSLGCILYQMVY-GRTP-FSHLSFYQKIREITNENHVINFPPVSNPLI
||| |..|.|| .   .|..       |.||..  .         .  .||.|| |  .. ..  |..| .  .| .. .. |. ...    |.   . |
DFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK--------FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEI

VDVMKSCLMWDKDKRPRIPQLLEHAFL
 |.||.| ..| ..||.  ..  | .|
YDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase TTK_a.AA ULK 53-126 19 0.000299 10.84 In-house 1-96 (329) Show / Hide 
Range on Protein: 53-126
Range on HMM: 1-96/329
Sequence Identity: 19% (19 aa)

YQKLGKIGSGGSSHVFKVIAQDC-----TIYALKRIILKGRDHQT--------ACGFHQEIEYLERLK----GKN---HIIQLIDYEVTD--KTIF
|..  ..|.|    |.| . ..       ..| | | ..  . .          . . .||. . .||    .||   .|..|.|.  |.  . |.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIY
Kinase TTK_a.AA ULK 53-126 21 0.000647 9.85 In-house 1-93 (324) Show / Hide 
Range on Protein: 53-126
Range on HMM: 1-93/324
Sequence Identity: 21% (20 aa)

YQKLGKIGSGGSS-HVFKVI-AQD---CTIYALKRIILKGRDHQTA--------CGFHQEIEYLERLK---GKN-HIIQLIDYEVTD--KTIF
|..  ..|.|     |.| .  ..     ..| | | .|.   .          . . .||. .  ||   ..| ||..|.|.  |.  . |.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIY
Kinase TTK_a.AA Ciliate-E2-Unclassified 53-84 32 0.003723 6.82 In-house 1-33 (352) Show / Hide 
Range on Protein: 53-84
Range on HMM: 1-33/352
Sequence Identity: 32% (11 aa)

YQKLGKIGSGGSSHVFKV--IAQDCTIYALKRII
| .. .||.|| . |.|.  . |.  .||.| ..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMK
Kinase TTK_a.AA AGC 53-83 23 0.017586 0.63 In-house 1-38 (395) Show / Hide 
Range on Protein: 53-83
Range on HMM: 1-38/395
Sequence Identity: 23% (9 aa)

YQKLGKIGSGGSSHVFKVIA-------QDCTIYALKRI
.. |  || |. . |. |         .   .||.| .
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVL
Kinase TTK_a.AA Ciliate-E2 53-87 18 0.066456 2.3 In-house 1-59 (365) Show / Hide 
Range on Protein: 53-87
Range on HMM: 1-59/365
Sequence Identity: 18% (11 aa)

YQKLGKIGSGGSSHVFKV--IAQDC----------------------TIYALKRIILKG
| .. |||.|. . |.|.  . ...                       |||.|... ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQ