Gene PEK_d (S.moellendorffii)
PEK_d
Species: S.moellendorffii
Alias: PEK_d
External Links:
Annotation:
Sequence
Protein domains of PEK_d.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | PEK_d.AA | PEK | 253-324 | 36 | 2.9e-20 | 63.27 | In-house | 686-758 (758) | Show / Hide |
Range on Protein: 253-324 Range on HMM: 686-758/758 Sequence Identity: 36% (27 aa) DVYSLGVLFFELFCV-FSSNMEWSRAMSDLRHRILPPRLLSESPKEAALCLWLLHPEPQSRPKAREIFQCELF | |||| ||||. || || | | ||| ..|...... |.|. . .......| || | .| .| DIYSLGLIFFELIHPGFSTQMERIRTMCDLRNGQWPKWFTQKYPQEYEFIQQMMSMNPDERPTADQISMHDFF |
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| Kinase | PEK_d.AA | PEK | 252-324 | 35 | 1.4e-19 | 64.22 | In-house | 575-655 (655) | Show / Hide |
Range on Protein: 252-324 Range on HMM: 575-655/655 Sequence Identity: 35% (29 aa) SDVYSLGVLFFELFCVFSSNM-EWSRAMSDLRH------RILP-PRLLSESPKEAALCLWLLHPEPQSRPKAREIFQCELF .|.||||..|||.. |.. | | .. . ||| ..| ... .. ||.| . .|.|.. || || | .| | |.| VDMYSLGIIFFEMWYPFFTTMMERVKTLTDLRDESIQFPGDFPPKWFDNKYPKQADFIQWMLSHDPQQRPSAQQILQHEFF |
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| Kinase | PEK_d.AA | HRI | 237-324 | 36 | 7.6e-12 | 37.26 | In-house | 526-613 (613) | Show / Hide |
Range on Protein: 237-324 Range on HMM: 526-613/613 Sequence Identity: 36% (32 aa) YTSPEELAGGASSFASDVYSLGVLFFELFCVFSSNMEWSRAMSDLRHRILPPRLLSESPKEAALCLWLLHPEPQSRPKAREIFQCELF | ||| | | || ||.|| |||| | || . .| .| | | | | || | . | ||| YASPEQLDGSQYDNKSDMYSMGVILFELFQPFGTEMERAEVLTGVRTGQIPESLRKRCPVQAKYIQHLTRRNASQRPSAIQLLQSELF |
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| Kinase | PEK_d.AA | GCN2 | 253-324 | 29 | 9.8e-11 | 33.39 | In-house | 434-511 (511) | Show / Hide |
Range on Protein: 253-324 Range on HMM: 434-511/511 Sequence Identity: 29% (23 aa) DVYSL-GVLFFELFCV-FSSNMEWSRAMSDLRHRILPPRLLS----ESPKEAALCLWLLHPEPQSRPKAREIFQCELF |.||| |..|||.. |.. || . .|| .|. . . ...... . |.| . ||.||.|... | |. DMYSLGGIIFFEMWYPPFCTQMERVQILKQLRSCEFPQDFDKKVDNHHKDQQDMIRWCLNHDPQKRPSAQQLLQHEFL |
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| Kinase | PEK_d.AA | PEK-Unclassified | 253-322 | 28 | 3.2e-08 | 23.65 | In-house | 766-835 (835) | Show / Hide |
Range on Protein: 253-322 Range on HMM: 766-835/835 Sequence Identity: 28% (20 aa) DVYSLGVLFFELFCVFSSNMEWSRAMSDLRHRILPPRLLSESPKEAALCLWLLHPEPQSRPKAREIFQCE |.||.|. ||..| . || .. .. .. || |. | . | .|| || | | DIYSVGIIFFQMFHQMNTTMERVKTIQNCKKGELPKHFCAKFPRLAEIIKDSLSNDPQKRPLLSKIEQTL |
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| Kinase | PEK_d.AA | RTKL | 239-263 | 48 | 1e-06 | 13.19 | In-house | 174-198 (259) | Show / Hide |
Range on Protein: 239-263 Range on HMM: 174-198/259 Sequence Identity: 48% (12 aa) SPEELAGGASSFASDVYSLGVLFFE ||| | |.. |||| ||. .| SPETLNGKPHTMASDVWAFGVVCYE |
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| Kinase | PEK_d.AA | Pkinase | 236-324 | 19 | 2e-06 | 24.14 | Pfam | 176-293 (293) | Show / Hide |
Range on Protein: 236-324 Range on HMM: 176-293/293 Sequence Identity: 19% (24 aa) WYTSPEELA-GGASSFASDVYSLGVLFFELFCVFSSNMEWSRA-------MSDLRHRILPPRLLSESPKE------------------------AALCLW || .|| . | . ..|..|.|....|..| . .. . . . ||..|.| ...|.. .. | WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC---GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW LLHPEPQSRPKAREIFQCELF .|.. |..|| |..|.| . | CLCKDPKKRPTAEQILQHPWF |
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| Kinase | PEK_d.AA | urchC | 237-261 | 44 | 2e-06 | 16.61 | In-house | 197-223 (223) | Show / Hide |
Range on Protein: 237-261 Range on HMM: 197-223/223 Sequence Identity: 44% (12 aa) YTSPEELA--GGASSFASDVYSLGVLF .. || | | . | |||.|| ||. HIAPEVLDIDGCQVSVASDIYSVGVIL |
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| Kinase | PEK_d.AA | Ciliate-E2 | 237-266 | 28 | 7e-06 | 16.24 | In-house | 253-291 (365) | Show / Hide |
Range on Protein: 237-266 Range on HMM: 253-291/365 Sequence Identity: 28% (11 aa) YTSPEELAGGA---------SSFASDVYSLGVLFFELFC | .|| | |. ....|..||||...|. . YMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF |
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| S_TKc | PEK_d.AA | S_TKc | 2-324 | 10 | 9e-06 | -91.92 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 2-324
Range on HMM: 1-231/231
Sequence Identity: 10% (37 aa)
KRKSTELGD-------AGIDLERRRDSSDNATTAASVFAQGPRSGSQSRVAASSSSVENRLPPASMELVLATDAGDGDTNMNDTGAEEEEEEDDGGN---
.. ..| ... . .. | . . |. . | . .. ..
YEILRKIGKGAFGKVYKCRHKK------TGRIVAIKIIK----------------------EHIRREIQILKK-----HHPNIVKLYDVFQD---DHLYM
--DHVGD--VTLRQWLRPGRT------VDRVACLHIFKQVLEFVELAQKQGVILRTIRPSCFMISPLHRI--------TFIESASSSDRSSEHSTGRAAD
.... .|.. .. .. . . ....|... .| ..|.| | . |. ... .| ...
VMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------
FPEQDMGMEAQRNVDAAAITDLQRALAQPDDQWTSSFDPSEPSSHEIDENFPLRQVLAKEQT-----WYTSPEELAGGASSFASDVYSLGVLFFELFC--
| || .|| | | . ...|..|.|....|..|
------------------------------------------------------------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGY
-VFSSNMEWSRAMSDLRHRILPPRLLSESPKEAALCLWLLHPEPQSRPKAREIFQ-------CELF
|. | . ..|. || . .|. .|. || | |..| . |
PPFP-------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | PEK_d.AA | TKL | 237-322 | 16 | 1.4e-05 | 16.12 | In-house | 239-364 (364) | Show / Hide |
Range on Protein: 237-322 Range on HMM: 239-364/364 Sequence Identity: 16% (21 aa) YTSPEELAGG----------------ASSFASDVYSLGVLFFELFC---VFSSNMEWSRA---------MSDLRHRILPPRL------------LSESPK . .|| | | | ..|||| |....|... ... ... .. | . .. ||. . | WMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPS EAALCLWLLHPEPQSRPKAREIFQCE . |. . ...|..|| . || . MKKLMQDCWDHDPEKRPSFQEILKRL |
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| Kinase | PEK_d.AA | PKR | 237-322 | 29 | 2.7e-05 | 14.75 | In-house | 189-272 (272) | Show / Hide |
Range on Protein: 237-322 Range on HMM: 189-272/272 Sequence Identity: 29% (25 aa) YTSPEELAGGASSFASDVYSLGVLFFELFCVFSSNMEWSRAMSDLRHRILPPRLLSESPKEAALCLWLLHPEPQSRPKAREIFQCE | ||| . |.| ||.. || | ..| .. |||. .. . . || .| || |. ||. || . YMSPEQIFSQHYGKEVDIYALGLILAELLHVCFTEFEKIKFFEDLRDGDFSNDIFDN--KEKTLLQKLLSKKPKDRPNTSEILRTL |
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| Kinase | PEK_d.AA | PEK | 98-126 | 31 | 0.004671 | 4.68 | In-house | 425-456 (758) | Show / Hide |
Range on Protein: 98-126 Range on HMM: 425-456/758 Sequence Identity: 31% (10 aa) TLRQWLRPG---RTVDRVACLHIFKQVLEFVE ||..|.| . ... .||.|.| .| |. TLKDWMRNRCTMESRPWMHMLHWFHQICEGVN |
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| Kinase | PEK_d.AA | PKR | 98-141 | 32 | 0.006562 | 6.1 | In-house | 107-152 (272) | Show / Hide |
Range on Protein: 98-141 Range on HMM: 107-152/272 Sequence Identity: 32% (15 aa) TLRQWL--RPGRTVDRVACLHIFKQVLEFVELAQKQGVILRTIRPS || ||. | . ||.| | .. |. . |. ...| | ..|| TLEQWMRNRRQEKVDKVLILDLYEQIVKGVDYIHSKKLIHRDLKPS |
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| Kinase | PEK_d.AA | PEK | 98-123 | 15 | 0.146224 | 0.32 | In-house | 369-438 (655) | Show / Hide |
Range on Protein: 98-123 Range on HMM: 369-438/655 Sequence Identity: 15% (11 aa) TLRQWLRPGR--------------------------------------------TVDRVACLHIFKQVLE |||.|.. .. .|.. |..||.|.|| TLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILE |
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| Kinase | PEK_d.AA | Ciliate-E2 | 304-324 | 22 | 0.208529 | 0.57 | In-house | 344-365 (365) | Show / Hide |
Range on Protein: 304-324 Range on HMM: 344-365/365 Sequence Identity: 22% (5 aa) LLHPEPQSRPK-AREIFQCELF .| .|. |. . .|.. . | MLQKDPEKRITGWEQILNHPWF |
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| WD40 | PEK_d.AA | WD40 | 504-548 | 11 | 0.00161 | 17.99 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 504-548 Range on HMM: 1-46/46 Sequence Identity: 11% (6 aa) RFEVKATLR-HGDLLNTANMVCSLSFDRDE------EFFATAGVCKKIKVFE .. .|.. | . |...... | ...|... ..|.... T-KCVHTFKGHTGN----SWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD |
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| WD40 | PEK_d.AA | WD40 | 523-548 | 14 | 0.017036 | 9.8 | Pfam | 13-39 (39) | Show / Hide |
Range on Protein: 523-548 Range on HMM: 13-39/39 Sequence Identity: 14% (4 aa) VCSLSFDRD-EEFFATAGVCKKIKVFE |...... | ..|... ..|.... VTCCAWHPDMGHYLASGSRDGTIRIWD |
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| WD40 | PEK_d.AA | WD40 | 559-598 | 22 | 0.007787 | 13.67 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 559-598 Range on HMM: 1-46/46 Sequence Identity: 22% (11 aa) IHYPVVEMA-SRS--KLSNICWNSYI-----KSHLASSDYDGVIQLWD .| .. .. . .||.. ...|||.. || | .|| T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD |
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| WD40 | PEK_d.AA | WD40 | 575-598 | 37 | 0.009966 | 10.47 | Pfam | 16-39 (39) | Show / Hide |
Range on Protein: 575-598 Range on HMM: 16-39/39 Sequence Identity: 37% (9 aa) ICWNSYIKSHLASSDYDGVIQLWD ..|. ..|||. || | .|| CAWHPDMGHYLASGSRDGTIRIWD |
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| WD40 | PEK_d.AA | WD40 | 602-641 | 25 | 8.8e-13 | 39.4 | Pfam | 1-39 (39) | Show / Hide |
Range on Protein: 602-641 Range on HMM: 1-39/39 Sequence Identity: 25% (10 aa) SQTLVEYKEHEKRAWSVDFSHADPTKLASGSDDGTVKLWS .. . .. .|.. ....... ... |||||.|||...|. WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD |
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| WD40 | PEK_d.AA | WD40 | 601-641 | 29 | 8.6e-11 | 43.09 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 601-641 Range on HMM: 1-46/46 Sequence Identity: 29% (14 aa) TSQTLVEYKEHEK--RAWSVDFSHAD-----PTKLASGSDDGTVKLWS | . . ..| |.. . ..|.... . |. ||||| |||...|. T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD |
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| WD40 | PEK_d.AA | WD40 | 644-683 | 25 | 0.007787 | 13.67 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 644-683 Range on HMM: 1-46/46 Sequence Identity: 25% (12 aa) QEASTGTIK-TKA--NVCCVQFPSDS-----AHLLTFGSADYKIYCYD . . |.| .. |.||.. .|. ..| || | .|...| T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD |
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| WD40 | PEK_d.AA | WD40 | 657-683 | 37 | 0.562315 | 5.43 | Pfam | 13-39 (39) | Show / Hide |
Range on Protein: 657-683 Range on HMM: 13-39/39 Sequence Identity: 37% (10 aa) VCCVQFPSDSAHLLTFGSADYKIYCYD |.|. . |. |.| ||.| .| .| VTCCAWHPDMGHYLASGSRDGTIRIWD |
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| WD40 | PEK_d.AA | WD40 | 688-725 | 20 | 4.1e-10 | 31.71 | Pfam | 1-39 (39) | Show / Hide |
Range on Protein: 688-725 Range on HMM: 1-39/39 Sequence Identity: 20% (8 aa) KGPLCILSSHNKAVSYVRFVDS--STIVSASTDSTLKLWD . .. .. |...|. ...... . ..|.| |.|...|| WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD |
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| WD40 | PEK_d.AA | WD40 | 687-725 | 20 | 1.3e-08 | 35.88 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 687-725 Range on HMM: 1-46/46 Sequence Identity: 20% (10 aa) TKGPLCILSSHNK--AVSYVRFVDS-------STIVSASTDSTLKLWD | ...... |.. .|. |.. .. . ..|.| |.|...|| T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD |
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| WD40 | PEK_d.AA | WD40 | 736-775 | 20 | 0.017375 | 11.47 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 736-775 Range on HMM: 1-46/46 Sequence Identity: 20% (10 aa) SNACSLTYTGHTN--EKNFVGLSVSD------GYIACGSETNAVFCYH . | |..|||. . . | . .. |.|.|| . . ... T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD |
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| WD40 | PEK_d.AA | WD40 | 737-775 | 22 | 0.614052 | 5.32 | Pfam | 1-39 (39) | Show / Hide |
Range on Protein: 737-775 Range on HMM: 1-39/39 Sequence Identity: 22% (9 aa) NACSLTYTGHTNEKNFVGLSVS-DGYIACGSETNAVFCYH | |. |||. . . . . |.|.||. . . . WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD |
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