Gene SRPK_b (S.moellendorffii)
SRPK_b
Species: S.moellendorffii
Alias: SRPK_b
External Links:
Annotation:
Sequence
Protein domains of SRPK_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | SRPK_b.AA | SRPK | 297-468 | 56 | 1.8e-137 | 356.48 | In-house | 383-554 (554) | Show / Hide |
Range on Protein: 297-468 Range on HMM: 383-554/554 Sequence Identity: 56% (97 aa) NRKTSHDVDLRCKIVDLGNACWTYKQFTADIQTRQYRCPEVLVGSKYSTPADMWSLACVVFELATGDVLFDPHTGEDYDRDEDHLALTMELLGRMPRKVA .| | ... ||.|||||||... || |||||||| |||..|..|.|||| ||.|| .||||||| ||.|| |||| ||.||.|. ||.|. |...| PRNADLDHKIKIKIADLGNACWVHHHFTEDIQTRQYRSPEVIIGAGYNTPADIWSTACMAFELATGDYLFEPHSGEDYSRDDDHIAHIIELCGKIPWHFA LGGRYSHDYFNRHGDLRHIRKLRFWPLKRVLVEKYDFSEVDAQDLSSFLCPILEFVPEKRLTAAQALQHSWL | |.|| ..||. |.|||| || .|||..||.|||..|. .|.. ..|| | |...|||| ||...||| || LSGKYSREFFNKKGELRHIPKLKPWPLMNVLIEKYEWSHEEAKQFEDFLMPMLHYNPEKRATAKECLQHPWL |
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| Kinase | SRPK_b.AA | SRPK | 72-228 | 46 | 2.2e-109 | 282.43 | In-house | 1-164 (554) | Show / Hide |
Range on Protein: 72-228 Range on HMM: 1-164/554 Sequence Identity: 46% (83 aa) YLVRKKLGWGHFSTVWLSSDRHNENVAGSSDLSLIFSFFQKNIALKIQKSAQHYTEAAMDEITILTQISKGDPE-----------------------NKK | | .||||||||||||. | .. |.||.|||.||||.| ||| .| ...| || |.. YHVIRKLGWGHFSTVWLCWD----------------MQYDRYVAMKIVKSAPHYTETAVDEIKLLQCVRKHDPNPQWMHFLKEYYEDYKRDCKEFDPNRC CVVKLLDHFRHTGPNGQHVCLVFELLGDNLLTLIKRHDCRGLPLQVVREISAQVLVGLDYLHRELSIIHTDLKPENILLT .||.|||||.|.||||.|.|.|||.||.||| .||... .|.|. |. |. ||| |||||||. .|||||.||||.||. HVVQLLDHFKHRGPNGNHYCMVFEVLGHNLLKWIKHYNYQGMPMHCVKQIARQVLIGLDYLHRKCGIIHTDIKPENVLLC |
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| Kinase | SRPK_b.AA | CMGC | 72-468 | 17 | 3.2e-92 | 303.3 | In-house | 1-513 (513) | Show / Hide |
Range on Protein: 72-468
Range on HMM: 1-513/513
Sequence Identity: 17% (104 aa)
YLVRKKLGWGHFSTVWLSSDRHNE---NVAGSSDLSLIFSFFQKN-----------IALKIQKSAQHYTEAAM-------------DEITILTQIS-KGD
| . ||.|.|....|. |.... | .|.|. |... |.| | .|| || ... ..|
YEIIKKIGEGTYGVVYKCRDKRTNQKKD----------------NGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHD
PEN----------KKC-VVKLLDHFRHTGPNGQ-------------HVCLVFELLGDNLLTLIKRHD--------------------------CRGLPLQ
| | .. .|||.|.|.| ...|. |..||||... .|. .||.. .. ...
P-NWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-
VVREISAQVLVGLD--YLHRE-LSIIHTDLKPENILLTTP-----------LPKARVFDHKNKSRAEENTDATGKEEIEAFQDAWKNIGLDKSCLEDAPS
.| .. |.| ||. |.|. ..|||.||||||||..
HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSE------------------------------------------------
DVEKLICEVKKPPPLASNRKTSHDVDLRCKIVDLGNACWTYKQ------------------------FTADIQTRQYRCPEVLVGSK----------YST
. ... ... | || | |.|.|. . .| ...|| || ||.|.|.| |.|
------------D-W-NPC----QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTT
PADMWSLACVVFELATG--------DVLFDPHTGE-----DYDRDEDHLALTMELLGRMPRKVALGGR-------YSHDYFNRHGDLRHIRKL-------
| ||||..|. .|. || . || .|... ..... |.|.. ...|| . ... |. .. ...|. . .... ..
PIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQT
------------------RFWPLKRVLVEKYDFSEV--------------------------------DAQDLSSFLCPILEFVPEKRLTAAQALQHSWL
|. .. . ... .. . ... .|. .|.. |.||.||.||||| ..
MTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
|
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| Kinase | SRPK_b.AA | S_TKc | 72-468 | 18 | 4.3e-57 | 196.9 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 72-468
Range on HMM: 1-231/231
Sequence Identity: 18% (77 aa)
YLVRKKLGWGHFSTVWLSSDRHNENVAGSSDLSLIFSFFQKNIALKIQKSAQHYTEAAMDEITILTQISKGDPENKKCVVKLLDHFRHTGPNGQHVCLVF
| . .|.| | |..|.. ... .. |.|| | | .. || || . . . .|||.|.|.. .|...|.
YEILRKIGKGAFGKVYKCRHKK----------------TGRIVAIKIIK------EHIRREIQILKK-------HHPNIVKLYDVFQD-----DHLYMVM
ELLGD---NLLTLIKRHDCRG----LPLQVVREISAQVLVGLDYLHRELSIIHTDLKPENILLTTPLPK------ARVFDHKNKSRAEENTDATGKEEIE
|... .|...||.. ..| .| ..| . .|.. .|.|.|. ||| |||||||||.. | ||..
EYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE-HIKICDFGLARQL---------------------
AFQDAWKNIGLDKSCLEDAPSDVEKLICEVKKPPPLASNRKTSHDVDLRCKIVDLGNACWTYKQFTADIQTRQYRCPEVLVGSKYST-PADMWSLACVVF
| . |. |. |||| .|.. ..|.||. |...
-----------------------------------------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY
ELATGDVLFDPHTGEDYDRDEDHLALTMELLGRMPRKVALGGRYSHDYFNRHGDLRHIRKLRFWPLKRVLVEKYDFSEVDAQDLSSFLCPILEFVPEKRL
|...| .|. .........| ... .|.. .|.. ||||.
EMLCGYPPFP------------QMQMMFKKIG------------------------------------------------SPEAKDFIRKCLQKDPEKRP
TAAQALQ-------HSWL
|| .||| | |.
TA-EALQDEWDIKCHPWF
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| Kinase | SRPK_b.AA | CLK | 72-392 | 25 | 5.6e-55 | 162.9 | In-house | 1-268 (350) | Show / Hide |
Range on Protein: 72-392
Range on HMM: 1-268/350
Sequence Identity: 25% (86 aa)
YLVRKKLGWGHFSTVWLSSDRHNENVAGSSDLSLIFSFFQKNIALKIQKSAQHYTEAAMDEIT-ILTQISKG-DPENKKC--VVKLLDHFRH-TGPNGQH
| . ..|| | |..| |. |.. | .|||| ... |.||| ||. |. .| . ||.||. ..|..| | . | |
YEIVCTLGEGTFGKVVECWDHKNGK---------------KYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHG----H
VCLVFELLGDNLLTLIKRHD------CRGLPLQVVREISAQVLVGLDYLHRELSIIHTDLKPENILLTTP-LPKARVFDHKNKSRAEENTDATGKEEIEA
.|.||||.| .. ..| ...|.. .|....| . . || .....|||||||||... . . || . | . ...
ICIVFELYGLSIYDFMKSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLH-DMKLTHTDLKPENICFVDSRF---THFDCTFKYNHKKKIN---------
FQDAWKNIGLDKSCLEDAPSDVEKLICEVKKPPPLASNRKTSHDVDLRCKIVDLGNAC---WTYKQFTADIQTRQYRCPEVLVGSKYSTPADMWSLACVV
| .. .. .| ... ...| |.| . .. ..||.|| ||| | .|.| | || .|.
------------------------------KKS-NNCVCHYWHVKNTHICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCIL
FELATGDVLFDPHTGEDYDRDEDHLALTMELLG-RMP
||| ||. ||. | .|||. ...| |
FELYTGFTLFQTHD------NREHLAMMERIMGMPIP
|
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| Kinase | SRPK_b.AA | DYRK | 111-227 | 38 | 1e-32 | 115.01 | In-house | 24-137 (320) | Show / Hide |
Range on Protein: 111-227 Range on HMM: 24-137/320 Sequence Identity: 38% (45 aa) QKNIALKIQKSAQHYTEAAMDEITILTQISKGDPENKKCVVKLLDHFRHTGPNGQHVCLVFELLGDNLLTLIKRHDCRGL-PLQVVREISAQVLVGLDYL .. .|.|| .. . . |..|| || ... ||..|. .|...|.| | .|.|.||||| || ..|.. .|. .|..|| . |.|..|..| NEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHR----NHLCIVFELLSMNLYEFLKNNHFQGFFSLNLVRKFAQQILTCLKFL HRELSIIHTDLKPENILL |.. .||| |||||||.| HKNENIIHCDLKPENIML |
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| Kinase | SRPK_b.AA | Pkinase | 72-390 | 19 | 5.3e-31 | 110.71 | Pfam | 1-233 (293) | Show / Hide |
Range on Protein: 72-390
Range on HMM: 1-233/293
Sequence Identity: 19% (64 aa)
YLVRKKLGWGHFSTVWLSSDRHNENVAGSSDLSLIFSFFQKNIALKIQKSAQHYTEAAMD-----EITILTQISKGDPENKKCVVKLLDHFRHTGPNGQH
| . .|.| | |..|.. .. .. |.|| | . . || |. .. ...|.|.| |. ..|
YHIGRKIGSGSFGCVYKCHHKGTGK----------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN------HPNIVRLYDWFED----KDH
VCLVFELLGD-----NLLTLIKRHDCRGL--PLQVVREISAQVLVGLDYLHRELSIIHTDLKPENILLT-TPLPKARVFDHKNKSRAEENTDATGKEEIE
...|.|... | ..|.... ... . .... . |.| ||.|.|. .||| ||||||||. .. ..|
IYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDA------------------------
AFQDAWKNIGLDKSCLEDAPSDVEKLICEVKKPPPLASNRKTSHDVDLRCKIVDLGNAC---WTYKQFTADIQTRQYRCPEVLV-GSKYSTPADMWSLAC
. || | | |. . . .| |. |. |||. |..|....||||. |
------------------------------------------------CVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGC
VVFELATGDVLFDPHTGEDYDRDEDHLALTMELLGR
...|...| .|. . . . |. |.... . .|.
ILYEMLCGRPPFP-GHC-WHDN-HDQMQMICRIMGP
|
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| Kinase | SRPK_b.AA | Ciliate-E2 | 72-468 | 15 | 6.4e-30 | 99.87 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 72-468
Range on HMM: 1-365/365
Sequence Identity: 15% (81 aa)
YLVRKKLGWGHFSTVWLSSD-RHNENVA---GSSDLSLIFS-----FFQKNIALKIQKSAQHYTEAAMDEITILTQISKGD-----------PENKKCVV
| . ||.| | |..|.. .. . ....| ... . . .| .|.||.| | |. . || |. .| . | . ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQ--IEQIKQEIHIMREINC-FYKKINEKNILEQLNHPNII
KLLDHFR--HTGPNGQHVCLVFELLGD-NLLTLIK-----------RHDCRGLPLQVVREISAQVLV---------------GLDYLHRELSIIHTDLKP
|. ..| . ... ||.|.. .|. .|| | . .. ...|..|.| .| ||| . .||| |.||
KMYECFQEKDD----NNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKP
ENILLTTPLPKARVFDHKNKSRAEENTDATGKEEIEAFQDAWKNIGLDKSCLEDAPSDVEKLICEVKKPPPLASNRKTSHDVDLRCKIVDLGNA------
||||. .||.|.|..
ENILF--------------------------------------------------------------------------------IKIIDFGLSKKYDDD
-----------CWTYKQ------------------FTADIQTRQYRCPEVLVGSK---------YSTPADMWSLACVVFELATGDVLFDPHTGEDYDRDE
... . | . | | .||.| | | |.. .|.||| .. .|. .| |
NQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------------
DHLALTMELLGRMPRKVALGGRYSHDYFNRHGDLRHIRKLRFWPLKRVLVEKYDFSEV--------------DAQDLSSF---LCP-----ILEFVPEKR
.. . |.||.. . ...| |. .|. ||||
--------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKR
LT-AAQALQHSWL
.| . |.|.| |.
ITGWEQILNHPWF
|
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| Kinase | SRPK_b.AA | DYRK2 | 111-227 | 38 | 2.6e-28 | 88.93 | In-house | 24-135 (318) | Show / Hide |
Range on Protein: 111-227 Range on HMM: 24-135/318 Sequence Identity: 38% (45 aa) QKNIALKIQKSAQHYTEAAMDEITILTQISKGDPENKKCVVKLLDHFRHTGPNGQHVCLVFELLGDNLLTLIKRHDCRGLPLQVVREISAQVLVGLDYLH .. .|.|. . . . | || || |.. |. | .|..|| | . |.|..||||. || .||.. |. || || ...| .|. || KQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRN----HHCITFELLSMNLYEYIKKNHFQGFSLQLVRRFAHSILQCLRFLH RELSIIHTDLKPENILL .. ||| ||||||||| KN-NIIHCDLKPENILL |
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| Kinase | SRPK_b.AA | DYRK | 309-468 | 31 | 1.9e-27 | 97.54 | In-house | 147-320 (320) | Show / Hide |
Range on Protein: 309-468 Range on HMM: 147-320/320 Sequence Identity: 31% (57 aa) KIVDLGNACWTYKQFTADIQTRQYRCPEVLVGSKYSTPADMWSLACVVFELATGDVLFDPHTGEDYDRDEDHLALTMELLGRMPRKVALGG--RYSHDYF |..| | .| .... || | || |||..| .|... ||||| |.. || || .|| ||.. | ||. ||.|| .|... | |. | .| KVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLFP---GENEY---DQLACIMEVLGMPPKWMIDKGRCRRKHKFF NR--------HGDLRHIRKLRFW----PLKRVLVEKYDFSE-------VDAQDLSSFLCPILEFVPEKRLTAAQALQHSWL .. . ..| . .. | || .... .. | ... |. |.. |.||.|..|||||.|. DCFMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQCDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF |
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| Kinase | SRPK_b.AA | HIPK | 114-227 | 38 | 1.9e-24 | 73.49 | In-house | 27-134 (329) | Show / Hide |
Range on Protein: 114-227 Range on HMM: 27-134/329 Sequence Identity: 38% (44 aa) IALKIQKSAQHYTEAAMDEITILTQISKGDPENKKCVVKLLDHFRHTGPNGQHVCLVFELLGDNLLTLIKRHDCRGLPLQVVREISAQVLVGLDYLHREL .|.|| | | |. || .|. .... . .|. .. |.| .|.|||||.| || | |||...| | ||| | | .|| VAIKILKNHPYYARQGQIEVSILHCLSQENADEYH-FVRAYECFHHK----NHTCLVFEMLEQNLYDFQKQNKFMPLPLKHIRPILQQVLTALMKL-KEL SIIHTDLKPENILL ..|| |||||||.| GLIHADLKPENIML |
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| Kinase | SRPK_b.AA | DYRK1 | 111-230 | 40 | 2.5e-23 | 78.43 | In-house | 24-140 (321) | Show / Hide |
Range on Protein: 111-230 Range on HMM: 24-140/321 Sequence Identity: 40% (49 aa) QKNIALKIQKSAQHYTEAAMDEITILTQISKGDPENKKCVVKLLDHFRHTGPNGQHVCLVFELLGDNLLTLIKRHDCRGLPLQVVREISAQVLVGLDYLH |. .|.|| | . . . | || .| . | |.|.| .|.| || . |.||||||| || |.. . || | ..| . |.. | .. QEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFR----NHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKFAQQMCTALLFMS R-ELSIIHTDLKPENILLTTP ||.||| ||||||||| | TPELDIIHCDLKPENILLCNP |
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| Kinase | SRPK_b.AA | DYRK2 | 309-410 | 36 | 1e-22 | 70.43 | In-house | 144-245 (318) | Show / Hide |
Range on Protein: 309-410 Range on HMM: 144-245/318 Sequence Identity: 36% (40 aa) KIVDLGNACWTYK-QFTADIQTRQYRCPEVLVGSKYSTPADMWSLACVVFELATGDVLFDPHTGEDYDRDEDHLALTMELLGRMPRKVALGG------RY |..| | | . .. .||.| || ||| .| ||... ||||. |.. || || || ||... | .|. ||.|| || |. . .. KVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLF---PGENEN---DQFACMMEVLG-MPPKKFFDTWFYIHCFR SHDYFNRHG .||.|. RKYFFNSHC |
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| Kinase | SRPK_b.AA | YAK | 114-230 | 38 | 1e-19 | 63.29 | In-house | 27-142 (347) | Show / Hide |
Range on Protein: 114-230 Range on HMM: 27-142/347 Sequence Identity: 38% (46 aa) IALKIQKSAQHYTEAAMDEITILTQI-SKGDPENKK---CVVKLLDHFRHTGPNGQHVCLVFELLGDNLLTLIKRHDCRGLPLQVVREISAQVLVGLDYL .| |. |. | | | || || . ||.|| .....| | | | |||||.| || ..| .|. |..| |.| |. | FAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHK----NHFCLVFEMLSNNLYEYLKQNKFCGFSFQLIRQWTKQILDGMCVL HRELSIIHTDLKPENILLTTP . ||| |||||||.| | -ENKQIIHCDLKPENIMLCKP |
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| Kinase | SRPK_b.AA | DYRK1 | 309-411 | 35 | 6.3e-16 | 51.98 | In-house | 146-242 (321) | Show / Hide |
Range on Protein: 309-411 Range on HMM: 146-242/321 Sequence Identity: 35% (37 aa) KIVDLGNACWTYKQFTADIQTRQYRCPEVLVGSKYSTPADMWSLACVVFELATGDVLFDPHTGEDYDRDEDHLALTMELLGRMPRKVALGGRYSHDYFNR ||.| | .| . . || | || ||||.| .|.. ||||| |.. |. ||. || .| . . | . .| || |... . .| ||.. KIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLF---SGSN---EVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEK HGD . | DPD |
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| Kinase | SRPK_b.AA | YAK | 309-359 | 49 | 1e-15 | 49.53 | In-house | 148-198 (347) | Show / Hide |
Range on Protein: 309-359 Range on HMM: 148-198/347 Sequence Identity: 49% (25 aa) KIVDLGNACWTYKQFTADIQTRQYRCPEVLVGSKYSTPADMWSLACVVFEL ||.| | .| . | . || | || ||..|. |.| ||||| |.| || KIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAEL |
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| Kinase | SRPK_b.AA | PRP4 | 132-226 | 35 | 1.5e-15 | 53.42 | In-house | 46-138 (320) | Show / Hide |
Range on Protein: 132-226 Range on HMM: 46-138/320 Sequence Identity: 35% (35 aa) EITILTQISKG--DPENKKCVVKLLDHFRHTGPNGQHVCLVFELLGDNLLTLIKRH-DCRGLPLQVVREISAQVLVGLDYLHRELSIIHTDLKPENIL |. || .. |.. |. .|.. .|| | || ||||| . || ..|. || | .|| . | .. | | . . |.| |.|| ||| ELEILQKLNDAPTDKNDKFHCVRMFRHFNHR----QHMCLVFECMSMNLREVLKKYGKDVGLHLKAVRSYAQQLFLALKHLKK-CNILHADIKPDNIL |
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| Kinase | SRPK_b.AA | PRP4 | 328-407 | 33 | 1.3e-12 | 42.61 | In-house | 167-240 (320) | Show / Hide |
Range on Protein: 328-407 Range on HMM: 167-240/320 Sequence Identity: 33% (27 aa) QTRQYRCPEVLVGSKYSTPADMWSLACVVFELATGDVLFDPHTGEDYDRDEDHLALTMELLGRMPRKVALGGRYSHDYFN . | || ||...| .| |||| .| .||.|| ..|. | . | | |.. | ||.| | . .|. VSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELYTGKIMFPGKT------NNHMLKLFMDYKGKMPNKMIRKGQFKDNHFD |
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| Kinase | SRPK_b.AA | HIPK | 307-359 | 40 | 4.5e-09 | 24.2 | In-house | 143-196 (329) | Show / Hide |
Range on Protein: 307-359 Range on HMM: 143-196/329 Sequence Identity: 40% (22 aa) RCKIVDLGNACWTYKQFTAD-IQTRQYRCPEVLVGSKYSTPADMWSLACVVFEL | |..| | | | . .| | || ||...| .. ||||| ||. || RVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAEL |
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| Kinase | SRPK_b.AA | DYRK2 | 444-468 | 40 | 1.9e-07 | 19.89 | In-house | 294-318 (318) | Show / Hide |
Range on Protein: 444-468 Range on HMM: 294-318/318 Sequence Identity: 40% (10 aa) FLCPILEFVPEKRLTAAQALQHSWL |. .| |..|.|..|||.| |. FIKRCFEWDPSERMTPSQALKHPWI |
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| Kinase | SRPK_b.AA | CLK | 448-468 | 47 | 3.1e-07 | 16.97 | In-house | 330-350 (350) | Show / Hide |
Range on Protein: 448-468 Range on HMM: 330-350/350 Sequence Identity: 47% (10 aa) ILEFVPEKRLTAAQALQHSWL .||. | ||.|...|||| . MLEYDPSKRITCKDALQHPFF |
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| Kinase | SRPK_b.AA | TyrKc | 72-468 | 13 | 5.5e-07 | -109.72 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 72-468
Range on HMM: 1-280/280
Sequence Identity: 13% (56 aa)
YLVRKKLGWGHFSTVWLSSDRHNENVAGSSDLSLIFSFFQKNIALKIQKSAQHYTEAAMDEITILTQI-SKGDPENKKCVVKLLDHFRHTGPNG---QHV
|||| |.| .|.. . . | | |. |. |.|. |.... . ...|.|. .. | | . .
ITLGKKLGEGAFGEVYKGTWK-------------------IQVAVKMLKEDA--REDFMREARIMCKLGG-----HHPNIVRLYGVCTQQGRNFMYIEPL
CLVFELL-GDNLLTLIKRHDCRGLPLQVVREISAQVLVGLDYLHRELSIIHTDLKPENILLTTPLPKARVFDHKNKSRAEENTDATGKEEIEAFQDAWKN
..|.|. . .|. ...| . |... ... |. | .|||. .|| || |.|.. ..
MIVMEYMPHGDLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENH-----------------------------------
IGLDKSCLEDAPSDVEKLICEVKKPPPLASNRKTSHDVDLRCKIVDLGNACWTYKQ----FTADIQTRQY--RCP----------EVLVGSKYSTPADMW
..|| | | . | | . . . |.. .|..| | |
----------------------------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVW
SLACVVFELATGDVLFDPHTGEDYDR-----DEDHLALTMELLGRMPRKVAL----GGRYSHDYFNRHGDLRHIRKLRFWPLKRVLVEKYDFSEVDAQDL
| . .|. | .. | .. .. |..... . | ...
SFGVCMWEIFTY-------GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------------F-VCCPDEM
SSFLCPILEFVPEKRLTAAQALQHSWL
. .. ||.| | .. |. .
YQIMKQCWHEDPEDRPTFSEI--HECF
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| Kinase | SRPK_b.AA | Pkinase | 430-468 | 22 | 8.2e-07 | 25.17 | Pfam | 236-293 (293) | Show / Hide |
Range on Protein: 430-468 Range on HMM: 236-293/293 Sequence Identity: 22% (13 aa) KYDFSEVDA-------------------QDLSSFLCPILEFVPEKRLTAAQALQHSWL ..|... . ... .|.. .|.. |.||.||.|.||| |. HFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | SRPK_b.AA | PRP4 | 453-468 | 43 | 0.00031 | 11.5 | In-house | 305-320 (320) | Show / Hide |
Range on Protein: 453-468 Range on HMM: 305-320/320 Sequence Identity: 43% (7 aa) PEKRLTAAQALQHSWL |.|| | .||.|. . PKKRITCNEALKHPFI |
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| Kinase | SRPK_b.AA | DYRK1 | 448-468 | 42 | 0.001492 | 7.78 | In-house | 301-321 (321) | Show / Hide |
Range on Protein: 448-468 Range on HMM: 301-321/321 Sequence Identity: 42% (9 aa) ILEFVPEKRLTAAQALQHSWL .|.. |..|.| .|||||.. MLQYDPKQRITPYYALQHSFF |
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| Kinase | SRPK_b.AA | YAK | 444-468 | 32 | 0.003452 | 6.24 | In-house | 323-347 (347) | Show / Hide |
Range on Protein: 444-468 Range on HMM: 323-347/347 Sequence Identity: 32% (8 aa) FLCPILEFVPEKRLTAAQALQHSWL |. .|. | .| .. || || . FINQLLQLNPRERWKPMQAMQHPFI |
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| Kinase | SRPK_b.AA | HIPK | 436-468 | 24 | 0.030194 | 2.32 | In-house | 297-329 (329) | Show / Hide |
Range on Protein: 436-468 Range on HMM: 297-329/329 Sequence Identity: 24% (8 aa) VDAQDLSSFLCPILEFVPEKRLTAAQALQHSWL .| .. .. | .. ..||.| ..||.|.. IDRREFVHVLKKMCTWDAHKRITPCEALNHPFV |
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| Kinase | SRPK_b.AA | PRP4 | 72-98 | 41 | 0.185095 | 1.21 | In-house | 1-29 (320) | Show / Hide |
Range on Protein: 72-98 Range on HMM: 1-29/320 Sequence Identity: 41% (12 aa) YLVRKKLGWGHFSTVWLSS--DRHNENVA | | . | | ||.| .| ||.|| YRVYGYCGQGVFSNVCRCRDQTRGNEMVA |
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