Gene CDK-Un_d (S.moellendorffii)

CDK-Un_d

Species: S.moellendorffii
Alias: CDK-Un_d
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
CDK-Un_d.AA Protein None 356 None Fasta, JSON
CDK-Un_d.NA RNA None 1071 None Fasta, JSON
CDK-Un_d.kin_dom Protein Kinase Domain None 311 None Fasta, JSON

Protein domain

Protein domains of CDK-Un_d.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CDK-Un_d.AA Pkinase 109-232 25 8.7e-20 71.05 Pfam 108-210 (293) Show / Hide 
Range on Protein: 109-232
Range on HMM: 108-210/293
Sequence Identity: 25% (32 aa)

REMRNLLRQLLLAVKACHDRNITHRDLKPEN-MVVQEPVDSTNKSIKWPANLSLRLIDFGSAIN--PFTLQHLYGSAGPSRNEHTPEYAPPEALLFDHWM
.| .. ..|.| ... ||...| |||||||| ....... ..          .....|||.|        . ... .|      ||.|..|| ..     
WECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA----------CVKICDFGLAKQFDY-NNS-MTTFCG------TPWYMAPEVIR-----

HFHPNQTKAHDIWSVGVIMLEIVLGTP
 ...  ... |.||.|.|. | ..| |
-GGQYYGPKVDMWSCGCILYEMLCGRP
Kinase CDK-Un_d.AA CAMK 112-224 25 1.5e-18 55.68 In-house 182-324 (425) Show / Hide 
Range on Protein: 112-224
Range on HMM: 182-324/425
Sequence Identity: 25% (39 aa)

RNLLRQLLLAVKACHDRNITHRDLKPENMVVQEPVDSTNKSIKWPAN--------LSLRLIDFGSA--INP-------------------------FTLQ
| . ||.. ||. ||..|| ||||||||  ...  |.... .    .          . .|||| |  ..|                           ..
RRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDP-V--E-HDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMK

HLYGSAGPSRNEHTPEYAP-PEALLFDHWMHF-------HPNQTKAHDIWSVGVIM
   |         ||||.. || |.  .   .       .|  ... |.||.|||.
TFCG---------TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVIL
Kinase CDK-Un_d.AA Ciliate-E2 99-232 19 3e-17 55.75 In-house 128-294 (365) Show / Hide 
Range on Protein: 99-232
Range on HMM: 128-294/365
Sequence Identity: 19% (37 aa)

RWLKTTKKGQ-------REMRNLLRQLLL---------------AVKACHDRN-ITHRDLKPENMVVQEPVDSTNKSIKWPANLSLRLIDFGSAI-----
...| ... .       .|.... .|.|                |.. .| .| | |||.|||| ..                  . .|||| .      
NKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------------------IKIIDFGLSKKYDDD

----------NPFTLQHLYGSAGPSRNEH------------TPEYAPPEALLF-----DHWMHFHPNQTKAHDIWSVGVIMLEIVLGTP
          . ..  . . |  |. ..             ||.| .|| |       .     .   ... ||||.|||. | . | |
NQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ---QKQKGYDYKCDIWSLGVILYEMLFGKP
Kinase CDK-Un_d.AA CMGC 39-169 16 2e-15 46.27 In-house 98-251 (513) Show / Hide 
Range on Protein: 39-169
Range on HMM: 98-251/513
Sequence Identity: 16% (31 aa)

NHVARFLDSFVVQG-----------------NLWLVFKKEGRSLSRLLYESE--------------------RAPGSNGSESKDKRLFEVVRPSAWWRWL
|.. . .|.|.  .                 .| |||   . .| .....                      | |                         
NNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRP-------------------------

KTTKKGQREMRNLL------RQLLLAVK--ACHDRN--ITHRDLKPENMVVQEP------------VDSTNKSIKWPANLSLRLIDFGSA
      ..  ....      .|.| ..|   || ..  | ||||||||  . .               . |.      |  |...|||.|
------PHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSED-W-NPC---QKNGRLKICDFGLA
Kinase CDK-Un_d.AA Ciliate-E2-Unclassified 109-232 20 1.4e-13 43.52 In-house 138-268 (352) Show / Hide 
Range on Protein: 109-232
Range on HMM: 138-268/352
Sequence Identity: 20% (32 aa)

REMR-----NLLRQLLLAVKACHDRN-ITHRDLKPENMVV---QEPVDSTNKSIKWPANLSLRLIDFGSAINPFT-------------------LQHLYG
....     ....|.|.. . .|  | | |||.|||| ..   ..             |. ...||||..... .                   ...  |
QQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-------------NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCG

SAG--PSRNEHTPEYAPPEALLF-DHW-MHFHPNQTKAHDIWSVGVIMLEIVLGTP
. .  | .      |..|| |    .  . .     .. ||||.|||. |.. |..
TPNYMP-Q------YTAPEVLQGQNYDHSKA-----YKCDIWSLGVILYEMLFGYY
S_TKc CDK-Un_d.AA S_TKc 9-350 14 4.1e-13 15.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-350
Range on HMM: 1-231/231
Sequence Identity: 14% (55 aa)

EIRLSGLRERHFGEIFLNASRSRLSTEEGLNHVARFLDSFVVQGNLWLVFKKEGRSLSR------LLYESERAPGSNGSESKDKRLFEVVRP---SAWWR
   |  . .  ||. ..   ..      |       ..           ...| . |..       ||.. .        ..    .| .     .  ..
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK---------EHIRREIQILKKHHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDY

WLKTTK------KGQREMRNLLRQLLLAVKACHDRNITHRDLKPENMVVQEPVDSTNKSIKWPANLSLRLIDFGSAINPFTLQHLYGSAGPSRNEHTPEY
  |  .          . | ...|...|.. ||...| ||||||||  . |                . ..|||.|               .    ||.|
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------------HIKICDFGLARQL------------TTFCGTPWY

APPEALLFDHWMHFHPNQTKAHDIWSVGVIMLEIVLGTP---HVFQISARTRVLLDRSLGGWDEESKNVAYMLRAFMEMCIFLPRVPPRHHRNETVNHQV
 .|| |         .  ... |.||.|.|. | . | |   .....  . .                                                
MAPEVL---------GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG------------------------------------------------

RYQLASMDCSEAALQRKIQQRDPLGLGMPDIWSFRLLRQLLQWYPEDRVSVDEALS-------HPYF
                             .     ..|..||. ||.| .. |||        ||.|
-----------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CDK-Un_d.AA Ciliate-E2a 110-139 51 1.4e-12 33.4 In-house 102-132 (275) Show / Hide 
Range on Protein: 110-139
Range on HMM: 102-132/275
Sequence Identity: 51% (16 aa)

EMRNLLRQLL-LAVKACHDRNITHRDLKPEN
|.. ...|||  ..  .| ||| ||||||||
EICDIMQQLLWQGLHYMHQRNIMHRDLKPEN
Kinase CDK-Un_d.AA CDC2 326-350 60 2.6e-11 30.5 In-house 277-301 (301) Show / Hide 
Range on Protein: 326-350
Range on HMM: 277-301/301
Sequence Identity: 60% (15 aa)

LLRQLLQWYPEDRVSVDEALSHPYF
||.|.||  |..|.|..|||.||||
LLMQMLQYDPQKRISAKEALQHPYF
Kinase CDK-Un_d.AA CLK 112-170 29 5.4e-11 28.47 In-house 117-195 (350) Show / Hide 
Range on Protein: 112-170
Range on HMM: 117-195/350
Sequence Identity: 29% (23 aa)

RNLLRQLLLAVKACHDRNITHRDLKPENMVVQEP-----------VDSTN---------KSIKWPANLSLRLIDFGSAI
|.. .||. |||  ||  .|| ||||||     .            .. .         . .. . |.  ..||||||.
RHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDSRFTHFDCTFKYNHKKKINKKSNNCVCHYWHVKNTHICVIDFGSAT
Kinase CDK-Un_d.AA CMGC 326-350 48 7.9e-11 30.86 In-house 489-513 (513) Show / Hide 
Range on Protein: 326-350
Range on HMM: 489-513/513
Sequence Identity: 48% (12 aa)

LLRQLLQWYPEDRVSVDEALSHPYF
|| ..||. |..| ....||.||||
LLKKMLQYDPDKRITAEQALQHPYF
Kinase CDK-Un_d.AA CDK 112-139 46 1.4e-10 29.94 In-house 111-138 (284) Show / Hide 
Range on Protein: 112-139
Range on HMM: 111-138/284
Sequence Identity: 46% (13 aa)

RNLLRQLLLAVKACHDRNITHRDLKPEN
.....||| ..  ||...| |||||| |
KCYMWQLLRGLHYCHSNWIMHRDLKPQN
Kinase CDK-Un_d.AA MAPK 326-350 52 3.3e-10 31.26 In-house 304-328 (328) Show / Hide 
Range on Protein: 326-350
Range on HMM: 304-328/328
Sequence Identity: 52% (13 aa)

LLRQLLQWYPEDRVSVDEALSHPYF
|| ..|.. |..| .|.|||.||||
LLEKMLVFDPDKRITVEEALQHPYF
Kinase CDK-Un_d.AA CDC2 112-142 45 6.3e-10 26.15 In-house 106-136 (301) Show / Hide 
Range on Protein: 112-142
Range on HMM: 106-136/301
Sequence Identity: 45% (14 aa)

RNLLRQLLLAVKACHDRNITHRDLKPENMVV
.... |.| .|  || | | |||||| |  .
KSYMYQILQGVHFCHQRRIMHRDLKPQNILI
Kinase CDK-Un_d.AA CDK 318-350 42 9.8e-10 27.15 In-house 255-284 (284) Show / Hide 
Range on Protein: 318-350
Range on HMM: 255-284/284
Sequence Identity: 42% (14 aa)

MPDIWSFRLLRQLLQWYPEDRVSVDEALSHPYF
.||     || ..|.  |. |.| ..||.||||
LPDY---DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CDK-Un_d.AA PHK 112-139 57 7.4e-09 25.99 In-house 112-139 (273) Show / Hide 
Range on Protein: 112-139
Range on HMM: 112-139/273
Sequence Identity: 57% (16 aa)

RNLLRQLLLAVKACHDRNITHRDLKPEN
| . |||. .|   | .|| ||||||||
RRIMRQLFEGVCYMHAHNIVHRDLKPEN
Kinase CDK-Un_d.AA PHK 326-350 40 4.5e-08 23.29 In-house 249-273 (273) Show / Hide 
Range on Protein: 326-350
Range on HMM: 249-273/273
Sequence Identity: 40% (10 aa)

LLRQLLQWYPEDRVSVDEALSHPYF
| ...||  |..|... |.| ||.|
LISKCLQVDPQQRITAEECLQHPFF
Kinase CDK-Un_d.AA Ciliate-E2a 326-350 36 1.1e-07 18.78 In-house 251-275 (275) Show / Hide 
Range on Protein: 326-350
Range on HMM: 251-275/275
Sequence Identity: 36% (9 aa)

LLRQLLQWYPEDRVSVDEALSHPYF
|....|. .|. | .  .|| ||.|
LMKKMLEKDPKKRITAQQALNHPWF
Kinase CDK-Un_d.AA CLK 324-350 40 1.3e-07 18.08 In-house 324-350 (350) Show / Hide 
Range on Protein: 324-350
Range on HMM: 324-350/350
Sequence Identity: 40% (11 aa)

FRLLRQLLQWYPEDRVSVDEALSHPYF
| |.|..|   |  |.. ..||.||.|
FDLIRKMLEYDPSKRITCKDALQHPFF
Kinase CDK-Un_d.AA Ciliate-E2 326-350 33 3.7e-07 20.6 In-house 336-365 (365) Show / Hide 
Range on Protein: 326-350
Range on HMM: 336-365/365
Sequence Identity: 33% (10 aa)

LLRQ----LLQWYPEDRVS-VDEALSHPYF
|...    .||  || | .  ...| ||.|
LIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CDK-Un_d.AA Ciliate-E2-Unclassified 304-350 25 1e-05 15.85 In-house 294-352 (352) Show / Hide 
Range on Protein: 304-350
Range on HMM: 294-352/352
Sequence Identity: 25% (15 aa)

LQRKIQQRDPLGLGMP-----DIWSF-------RLLRQLLQWYPEDRVSVDEALSHPYF
|...|.|...    .|     ..||.       .||...|.. |. | . ...| ||.|
LYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CDK-Un_d.AA CAMK 326-350 40 0.000141 9.88 In-house 401-425 (425) Show / Hide 
Range on Protein: 326-350
Range on HMM: 401-425/425
Sequence Identity: 40% (10 aa)

LLRQLLQWYPEDRVSVDEALSHPYF
|.|..||  ||.| .....|.|| .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CDK-Un_d.AA Pkinase 326-350 28 0.000388 15.71 Pfam 269-293 (293) Show / Hide 
Range on Protein: 326-350
Range on HMM: 269-293/293
Sequence Identity: 28% (7 aa)

LLRQLLQWYPEDRVSVDEALSHPYF
... .|.. |..| . ...| ||.|
FIKWCLCKDPKKRPTAEQILQHPWF
Kinase CDK-Un_d.AA MAPK 212-232 50 0.000829 8.79 In-house 212-233 (328) Show / Hide 
Range on Protein: 212-232
Range on HMM: 212-233/328
Sequence Identity: 50% (11 aa)

TKAHDIWSVGVIMLEIVL-GTP
||| |.|||| |. | .  ..|
TKAVDMWSVGCIFAEMLTDRKP
Kinase CDK-Un_d.AA CDK 216-232 40 0.001277 7.27 In-house 204-223 (284) Show / Hide 
Range on Protein: 216-232
Range on HMM: 204-223/284
Sequence Identity: 40% (8 aa)

DIWSVGVIMLEIVL---GTP
|.|||| |. |...   . |
DMWSVGCIFAEMFTDVTRKP
Kinase CDK-Un_d.AA CMGC 212-232 34 0.001536 6.47 In-house 313-341 (513) Show / Hide 
Range on Protein: 212-232
Range on HMM: 313-341/513
Sequence Identity: 34% (10 aa)

TKAHDIWSVGVIMLEIVLG--------TP
|.. |.|||| |. |...|         |
TTPIDMWSVGCIFAEMYTGYQSLIFRGKP
Kinase CDK-Un_d.AA MAPK 129-142 64 0.008115 5.31 In-house 137-150 (328) Show / Hide 
Range on Protein: 129-142
Range on HMM: 137-150/328
Sequence Identity: 64% (9 aa)

NITHRDLKPENMVV
|. ||||||.| .|
NVIHRDLKPSNILV
Kinase CDK-Un_d.AA CDC2 216-232 40 0.020985 2.61 In-house 188-207 (301) Show / Hide 
Range on Protein: 216-232
Range on HMM: 188-207/301
Sequence Identity: 40% (8 aa)

DIWSVGVIMLEI---VLGTP
|.||.| |. |.   |   |
DMWSIGCIFAEMFMDVTKKP