Gene CDK-Un_b (S.moellendorffii)

CDK-Un_b

Species: S.moellendorffii
Alias: CDK-Un_b
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
CDK-Un_b.AA Protein None 244 None Fasta, JSON
CDK-Un_b.NA RNA None 735 None Fasta, JSON
CDK-Un_b.kin_dom Protein Kinase Domain None 72 None Fasta, JSON

Protein domain

Protein domains of CDK-Un_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CDK-Un_b.AA CMGC 31-74 27 1.6e-13 39.85 In-house 183-249 (513) Show / Hide 
Range on Protein: 31-74
Range on HMM: 183-249/513
Sequence Identity: 27% (19 aa)

IRKILREILVALK--KMHATG--IVHRDVKPANLVVTNKAKL--------------------KFIDFG
|| . . || .||   .|  .  |.||| ||.|. .... .|                    | .|||
IR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFG
Kinase CDK-Un_b.AA CDK-DD1 42-77 50 4.4e-13 36.12 In-house 111-146 (379) Show / Hide 
Range on Protein: 42-77
Range on HMM: 111-146/379
Sequence Identity: 50% (18 aa)

LKKMHATGIVHRDVKPANLVVTNKAKLKFIDFGAAT
.. .|  || |||.||||| ..|.  ||  ||| .|
INECHNQGIMHRDIKPANLLINNRGDLKITDFGFTT
Kinase CDK-Un_b.AA CK2 31-76 48 7.5e-12 30.9 In-house 97-143 (288) Show / Hide 
Range on Protein: 31-76
Range on HMM: 97-143/288
Sequence Identity: 48% (23 aa)

IRKILREILVALKKMHATGIVHRDVKPANLVV-TNKAKLKFIDFGAA
||  ..|.| ||   |  ||.||||||.| ..  .| ||. || | |
IRYYMFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLA
Kinase CDK-Un_b.AA PEK-Unclassified 32-79 38 1.4e-11 35.73 In-house 616-665 (835) Show / Hide 
Range on Protein: 32-79
Range on HMM: 616-665/835
Sequence Identity: 38% (19 aa)

RKILREILVALKKMHATG-IVHRDVKPANLVVTNK-AKLKFIDFGAATDL
| |.|.|..||.  |  . .||||.|| |  |..     |  ||| .. .
REITRQIIKALYHIHHQCKMVHRDIKPHNIFVCQNPMQIKIGDFGLVKKI
Kinase CDK-Un_b.AA CDK 31-74 34 5.7e-11 31.16 In-house 110-158 (284) Show / Hide 
Range on Protein: 31-74
Range on HMM: 110-158/284
Sequence Identity: 34% (17 aa)

IRKILREILVALKKMHATGIVHRDVKPANLVVTNKAK-----LKFIDFG
|. ... .| .|  .|  .|.||| ||.|. ..|. .     ||  |||
IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFG
Kinase CDK-Un_b.AA CDK4 30-74 37 8.5e-11 33.05 In-house 111-155 (290) Show / Hide 
Range on Protein: 30-74
Range on HMM: 111-155/290
Sequence Identity: 37% (17 aa)

TIRKILREILVALKKMHATGIVHRDVKPANLVVTNKAKLKFIDFG
||... ...| ..   |.  |.||| || |. ||   ..|  |||
TIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFG
Kinase CDK-Un_b.AA RCK 2-76 26 1.1e-10 29.88 In-house 96-161 (298) Show / Hide 
Range on Protein: 2-76
Range on HMM: 96-161/298
Sequence Identity: 26% (22 aa)

KDRRFPENLAEPLLGRSREKDPLKRKALTIRKILREILVALKKMHATGIVHRDVKPANLVVTN---------KAKLKFIDFGAA
.....|||                     |..|.  || .|. || .|. |||.|| |. .|.            .| .||| .
RRKYLPENQR------------------SIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLC
Kinase CDK-Un_b.AA p38 38-76 48 3.2e-10 30.83 In-house 115-153 (289) Show / Hide 
Range on Protein: 38-76
Range on HMM: 115-153/289
Sequence Identity: 48% (19 aa)

ILVALKKMHATGIVHRDVKPANLVVTNKAKLKFIDFGAA
|| .||  |. ||.||| || |. |.    |.  ||| |
ILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLA
Kinase CDK-Un_b.AA Pkinase 30-101 29 6e-10 36.25 Pfam 109-182 (293) Show / Hide 
Range on Protein: 30-101
Range on HMM: 109-182/293
Sequence Identity: 29% (23 aa)

TIRKILREILVALKKMHATGIVHRDVKPANLVVTNKAKL----KFIDFGAATD--LRVGKNYVPERGMLDPDYCPPEL
........|| .|. .|. ||.|||.||.|. . |.  .    | .||| |    .  .  .    |   |.|..||.
ECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCG--TPWYMAPEV
Kinase CDK-Un_b.AA CDC2 30-74 33 1.8e-09 24.69 In-house 104-148 (301) Show / Hide 
Range on Protein: 30-74
Range on HMM: 104-148/301
Sequence Identity: 33% (15 aa)

TIRKILREILVALKKMHATGIVHRDVKPANLVVTNKAKLKFIDFG
......  || ..   |. .|.||| || |. . .|...|  |||
LVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFG
S_TKc CDK-Un_b.AA S_TKc 1-241 13 6.4e-08 -60.72 SMART 18-231 (231) Show / Hide 
Range on Protein: 1-241
Range on HMM: 18-231/231
Sequence Identity: 13% (42 aa)

MKDRR----------------------------------FP--------ENLAE---PLLGRSREKDPLK----RKALTIRKILREILVALKKMHATGIV
 ....                                  |         | .      |. . ... . .        ..|.....|. ||. .|  ||.
CRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGII

HRDVKPANLVVTNKAKLKFIDFGAATDLRVGKNYVPERGMLDPDYCPPELFVMPEETPRPPPAPIAALLSPILWQVSQELFLCTFSWRCSSFFFFLQLNS
|||.||.|. ...   .| .||| |. |              |.|..||..                                                .
HRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----------------------------------------------GYG

PDLFDMYSVGIIFLQMAS---PNLRTPVAVEVMKKELSEVNFDLKAWRKRTRLRPNFELLELGAGRGWELASRLVC-ERRKRLSAAAALR-------HPY
.   |..|.|.|.  |..   |       ...| | .                             .... ... . . .||..|  ||.       ||.
KCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPW

F
|
F
Kinase CDK-Un_b.AA CDK5 222-241 60 8.3e-08 20.24 In-house 268-287 (287) Show / Hide 
Range on Protein: 222-241
Range on HMM: 268-287/287
Sequence Identity: 60% (12 aa)

LVCERRKRLSAAAALRHPYF
|.|.  .|.||.|||.||||
LQCNPNQRISAKAALHHPYF
Kinase CDK-Un_b.AA CDK5 46-76 45 2.5e-07 18.69 In-house 115-145 (287) Show / Hide 
Range on Protein: 46-76
Range on HMM: 115-145/287
Sequence Identity: 45% (14 aa)

HATGIVHRDVKPANLVVTNKAKLKFIDFGAA
|.  . ||| || || .  . .||  ||| |
HEHHVLHRDLKPQNLLINKNGELKLADFGLA
Kinase CDK-Un_b.AA CMGC 222-241 50 3e-07 18.88 In-house 494-513 (513) Show / Hide 
Range on Protein: 222-241
Range on HMM: 494-513/513
Sequence Identity: 50% (10 aa)

LVCERRKRLSAAAALRHPYF
|...  ||..|. ||.||||
LQYDPDKRITAEQALQHPYF
Kinase CDK-Un_b.AA CDK 222-241 55 6.3e-07 18.02 In-house 265-284 (284) Show / Hide 
Range on Protein: 222-241
Range on HMM: 265-284/284
Sequence Identity: 55% (11 aa)

LVCERRKRLSAAAALRHPYF
|...  ||.|| .|| ||||
LCYDPKKRISAEQALQHPYF
Kinase CDK-Un_b.AA CDC2 228-241 71 2e-06 15.05 In-house 288-301 (301) Show / Hide 
Range on Protein: 228-241
Range on HMM: 288-301/301
Sequence Identity: 71% (10 aa)

KRLSAAAALRHPYF
||.|| .||.||||
KRISAKEALQHPYF
Kinase CDK-Un_b.AA RCK 228-241 64 3e-06 15.64 In-house 285-298 (298) Show / Hide 
Range on Protein: 228-241
Range on HMM: 285-298/298
Sequence Identity: 64% (9 aa)

KRLSAAAALRHPYF
|| .|..||.||||
KRITAQQALQHPYF
Kinase CDK-Un_b.AA CDK4 228-241 64 1.6e-05 14.69 In-house 277-290 (290) Show / Hide 
Range on Protein: 228-241
Range on HMM: 277-290/290
Sequence Identity: 64% (9 aa)

KRLSAAAALRHPYF
||.|| ..| ||||
KRMSAYQCLQHPYF
Kinase CDK-Un_b.AA p38 228-241 57 1.6e-05 14.5 In-house 276-289 (289) Show / Hide 
Range on Protein: 228-241
Range on HMM: 276-289/289
Sequence Identity: 57% (8 aa)

KRLSAAAALRHPYF
||..|. |..||||
KRITAEEAMQHPYF
Kinase CDK-Un_b.AA CK2 222-241 40 7.7e-05 9.55 In-house 269-288 (288) Show / Hide 
Range on Protein: 222-241
Range on HMM: 269-288/288
Sequence Identity: 40% (8 aa)

LVCERRKRLSAAAALRHPYF
|.    .|..|  |. ||||
LRYDHQERITAKEAMEHPYF
Kinase CDK-Un_b.AA CDK-DD1 228-241 50 7.9e-05 10.18 In-house 366-379 (379) Show / Hide 
Range on Protein: 228-241
Range on HMM: 366-379/379
Sequence Identity: 50% (7 aa)

KRLSAAAALRHPYF
||...  || ||.|
KRINTKEALQHPWF
Kinase CDK-Un_b.AA PEK-Unclassified 156-170 66 0.001315 7.09 In-house 766-780 (835) Show / Hide 
Range on Protein: 156-170
Range on HMM: 766-780/835
Sequence Identity: 66% (10 aa)

DMYSVGIIFLQMASP
|.|||||||.|| ..
DIYSVGIIFFQMFHQ
Kinase CDK-Un_b.AA Pkinase 228-241 50 0.011185 10.55 Pfam 280-293 (293) Show / Hide 
Range on Protein: 228-241
Range on HMM: 280-293/293
Sequence Identity: 50% (7 aa)

KRLSAAAALRHPYF
||..|. .| ||.|
KRPTAEQILQHPWF