CDK-Un_e

Species: S.moellendorffii
Alias: CDK-Un_e
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
CDK-Un_e.AA Protein None 737 None Fasta, JSON
CDK-Un_e.NA RNA None 2214 None Fasta, JSON
CDK-Un_e.kin_dom Protein Kinase Domain None 261 None Fasta, JSON

Protein domain

Protein domains of CDK-Un_e.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CDK-Un_e.AA TKL 211-463 23 4.7e-72 245.68 In-house 1-364 (364) Show / Hide
Range on Protein: 211-463
Range on HMM: 1-364/364
Sequence Identity: 23% (89 aa)

LGQGASGTVYRADWLG----------QAVAVKVFKRDD-----------------------------VTFEREVAALV---APHPHVLQVIG--------
.|.|..|.||.. | |          . ||||.||...                               |..|. ...     ||...| .|        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-YLGA---GDGDPVIVMELM-RMDLRRFLDAGGGGGAPFHLAVDLLLQIARGTRFLHDHG--------VVHRDLKPQNVLVDFDGD--------DRRMVN
 . .    ..|.. ||||.. . .|. .|         .|. ... |.||||  .|| ..        ..|||||..|.||| ..             ..
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

VLLTDFGIARTGFDSMVNDLTS------------------LRGTPRYMAPEMMASA-----AAAL------GGYSRKVDVYSFGVLCSEVLTGSPPFG-D
. ..|||..|. . |. .  |.                   .||||.||||..  .     .. .      . || |.||||||..  |.||. .|.  .
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

KRWLGI------NEVREMVDSGKRPELP------------ASCPGELRDLITRCWSADAESRPAFSEIEREL
.    |       .    .| |.||..|             .|| ....|...||..|.|.|| |.||  .|
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

S_TKc CDK-Un_e.AA S_TKc 205-471 27 2.8e-61 210.8 SMART 1-231 (231) Show / Hide
Range on Protein: 205-471
Range on HMM: 1-231/231
Sequence Identity: 27% (77 aa)

WEPADKLGQGASGTVYRADWLG--QAVAVKVFKRDDVTFEREVAALVAPHPHVLQVIGYLGAGDGDPVIVMELMRM---DLRRFLDAGGGGG----APFH
.|  .|.|.|| |.||.. . .  . ||.|. |    ...||.. |   ||.. . ...     ..  .|||..     ||.....  |..|     |  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKKHHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-

LAVDLLLQIARGTRFLHDHGVVHRDLKPQNVLVDFDGDDRRMVNVLLTDFGIARTGFDSMVNDLTSLRGTPRYMAPEMMASAAAALGGYSR-KVDVYSFG
 |  .. ||...  ..|.||..||||||.|.|.|         .. ..|||.||          |.. ||| |||||..        ||.. |.|..|.|
HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------HIKICDFGLARQL--------TTFCGTPWYMAPEVL--------GYGKCKCDWWSCG

VLCSEVLTGSPPFGDKRWLGINEVREMVDSGKRPELPASCPGELRDLITRCWSADAESRPAFSEIER-ELASIKRKLL
..  | |.| |||         .. .| .  .        . |..|.| .|.  | | ||   |. . |..  .   .
CILYEMLCGYPPFP--------QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Pkinase CDK-Un_e.AA Pkinase 205-459 25 3.6e-49 174.46 Pfam 1-287 (293) Show / Hide
Range on Protein: 205-459
Range on HMM: 1-287/293
Sequence Identity: 25% (75 aa)

WEPADKLGQGASGTVYRADWLGQA--VAVKVFKRDDVTF----------EREVAALVAPHPHVLQVIGYLGAGDGDPVIVMELMRM-----DLRRFLDAG
..   |.|.|..|.||.. . |    ||||..|...             | .. . .  ||.... ...    .... .|||....     || ... . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTW

GGGGA--PFHLAVDLLLQIARGTRFLHDHGVVHRDLKPQNVLVDFDGDDRRMVNVLLTDFGIARTG-FDSMVNDLTSLRGTPRYMAPEMMASAAAALGGY
 .|.   . . . . ..||.||  ..|..|..||||||.|.|.| .|.      | ..|||.|.     . .  .|.. |||.|||||          .|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIR----GGQYY

SRKVDVYSFGVLCSEVLTGSPPFGDK-RWLGINEVREMVDSGKRPELPASCP-----------------------GELRDLITRCWSADAESRPAFSEI
..|||..|.|... |.|.| ||| ..    . .. ..|..  ..|.|. ..|                        |..|.|..|.  | ..|| . .|
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

Kinase CDK-Un_e.AA MLK 205-463 26 1.2e-48 166.89 In-house 1-291 (291) Show / Hide
Range on Protein: 205-463
Range on HMM: 1-291/291
Sequence Identity: 26% (78 aa)

WEPADKLGQGASGTVYRADWLGQA-----VAVKVFK-------------RDDVTFEREVAALVAPH--PHVLQVIGYLGAGDGDPVIVMELMRM-DLRRF
 .   ..| |..| |... | ..      |||| ..             .|  .. |... |  |   | . |. |       . .|||| ..   | ..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LDAGGGGGA------------PFHLAVDLLLQIARGTRFLHDHG---VVHRDLKPQNVLVD-FDGDDRRMVNVLLTDFGIARTGFDSMVND---LTSLRG
| .. ....            ....|..  ||.|||  .|| .    ..|||||..|.|.|   . | .  ..  .|||..|    .. .     .| .|
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICH-DMHHGTLKICDFGTSR----DWHQMCTNMMSNAG

TPRYMAPEMMASAAAALGGYSRKVDVYSFGVLCSEVLTGSPPFGDK-RWLGINEVREMVDSGKRPELPASCPGELRDLITRCWSADAESRPAFSEIEREL
|...||||.     .  . ||.|.||.|.||.  |.||.  |.  |  . ..    ...  |.|| .| .||  .  |...||..|...|| |..|  .|
TYAWMAPEVIQQ--FRCEKYSEKCDVWSWGVVLWEMLTREVPY--KQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL





Kinase CDK-Un_e.AA TKL-Unique 207-463 28 9.3e-45 155.01 In-house 1-290 (290) Show / Hide
Range on Protein: 207-463
Range on HMM: 1-290/290
Sequence Identity: 28% (86 aa)

PADKLGQGASGTVYRADWLGQAVAVKVFK-RDDVT------FEREV--AALVAPHPHVLQVIGYLG---AGDGDPVIVMELMRMD-LRRFLDA-------
.  |.|.|..|.||.. | |  ||.|.|.   |.       ||.||       .|| ... .||        ..  |||| . .  |.  |.        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-GGGGGAPFHLAVDLLLQIARGTRFLHDHG--VVHRDLKPQNVLVDFDGDDRRM-----VNVLLTDFGIARTGFDSMVNDLT--------SLRGTPRYMA
       .. . |.. ..||.|  .||  .  . |||||..|.|||      .      .|. . |||....   .. . ..        .  |..|.||
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVD------NNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMA

PEMMASAAAALGGYSRKVDVYSFGVLCSEVLTGSP------PFGDKRWLGINEVREMVDS---GKRPELPASCPGELRDLITRCWSADAESRPAFSEIER
||.. .       ||.|.||||||.   | .|.        |. .   .  ....|||..   ..||..| .|| |.||||..||  | . || |.||  
PEVLRMNF---CQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQG---MDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIH

EL
.|
RL

Kinase CDK-Un_e.AA TK 205-463 17 2.9e-42 138.97 In-house 1-486 (486) Show / Hide
Range on Protein: 205-463
Range on HMM: 1-486/486
Sequence Identity: 17% (87 aa)

WEPADKLGQGASG---TVYRADWLG---------------------------QAVAVKVFK---RDDVT------------------FEREVAALV---A
 .  .|||.|. |   .||.. | |                           . ||||. |    .. .                  . .| . .     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

PHPHVLQVIGYLGAGDGD-----------PVIVMELMR-MD----LRRFLDAGGGGGAP-----------------------------------------
 ||.... .|.   |..            . ||||.|   |    || .| .  ... .                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------FHLAVD-------------------LLLQIARGTRFLHDH------GVVHRDLKPQNVLVDFDGDDRRMVN------VLLTDFGIA-
             ..  ..                     .|||.| ..||..      ..|||||   |.||. .. ...  .      . ..||| . 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWH-FDGCGPVCKIADFGLSR

-------RTGF-------------------------DSMVNDLTSLRGTPRYMAPEMMA----SAAAALGGYSRKVDVYSFGVLCSEVLT-G-SPPFGDK
       |                            .. . . .. .   |.|||| ..    | | . | .. | ||.|||||. |..| |  |. |. 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

RWLGI------NEVREMVDSG--------------KRPELPASCP--------------GELRDLITRCWSADAESRPAFSEIEREL
   .        || |.. .|               |.. |. ||               |. ||...||..|.| || ||.. ..|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase CDK-Un_e.AA Dicty4 209-465 29 5.3e-40 131.21 In-house 5-277 (277) Show / Hide
Range on Protein: 209-465
Range on HMM: 5-277/277
Sequence Identity: 29% (83 aa)

DKLGQGASGTVYRADWLGQAVAVKVF--KRDDV------TFEREVAALVA-PHPHVLQVIGYLGA---GDGDPVIVMELM-RMDLRRFLDA-----GGGG
...|.|. |.||.. | |..||||..  . ...       | .||. .    ||....  |.  |     |...||.|.| . .| . | .         
QRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSI

GAPFHLAVD---LLLQIARGTRFLHD--HGVVHRDLKPQNVLVDFDGDDRRMVNVLLTDFGIAR-TGFDSMVND-LTSLRGTPRYMAPEMMASAAAALGG
  .. |      . . .|||   ||     ..|||||. | ||| .       .|  .|||...    ... .| ...  ||| .||||.|.. .     
KLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKN------WRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP-----

YSRKVDVYSFGVLCSEVLTGSPPFGDKRWLGINEVREMVDS-GKRPELPASCPGELRDLITRCWSADAESRPAFSEIERE--LAS
|  |.|||||| .  | ||.  |.  |    . .... |.. . ||..|..||  ...||..||. | ..|| |.||  .  | .
YNEKADVYSFGIVLWEILTRQEPYQ-KHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase CDK-Un_e.AA LRRK 302-465 31 8.8e-39 134.82 In-house 171-351 (351) Show / Hide
Range on Protein: 302-465
Range on HMM: 171-351/351
Sequence Identity: 31% (60 aa)

LQIARGTRFLHDHG--VVHRDLKPQNVLV-DFDGDD-----RRMVNVLLTDFGIARTGFDSMVND--LTSLRGTPRYMAPEMMA----SAAAALGGYSRK
||||.| ..||.|   ..|||||. |.|.  .. ..     .  |.. . |||| |  | . .    .  . |.|..|||| |     .       |. |
LQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEE------YTEK

VDVYSFGVLCSEVLTGS-PPFGDKRWLG----INEVREMVDSGKRPELPAS-CPG-----ELRDLITRCWSADAESRPAFSEIERELAS
||.||||..  | ||.. .||..    .    ...... . .| || .| . ||.     .. |||. ||..| ..|| ||.|   | .
VDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase CDK-Un_e.AA Pkinase_Tyr 210-463 30 1.5e-38 131.22 Pfam 6-270 (270) Show / Hide
Range on Protein: 210-463
Range on HMM: 6-270/270
Sequence Identity: 30% (84 aa)

KLGQGASGTVYRADWL------GQAVAVKVF--KRDDVT-----FEREVAALVAP--HPHVLQVIGYLGAGDGD--PVIVMELMRM-DLRRFLDAG--GG
|||.|| |.||.. |       .. ||||.   . ..       | ||.. .     ||.... .|     ..   . ||||.|   ||. .| .   ..
KLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDK

GGAPFHLAVDLLLQIARGTRFLHDHGVVHRDLKPQNVLVDFDGDDRRMVNVLLTDFGIARTG-FDSMV-NDLTSLRGTPRYMAPEMMASAAAALGGYSRK
.  . .  ..  .|||.|  .|.... .||||   |.||.     . .  |  .||| ||.   |.      .. .   . |||| ..        .. |
QPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVT-----ENN-VVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-----FTTK

VDVYSFGVLCSEVLT-GSPPFGDKRWLGINEVREMV-DSGKRPELPASCPGELRDLITRCWSADAESRPAFSEIEREL
 ||.|||||. |..| |  |  .   .  .|| |.. ..| | . |  || |. ||...|| .|.| || |||| ..|
SDVWSFGVLMWEIFTYGEQP--TYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase CDK-Un_e.AA STE 205-409 23 9.7e-36 123.7 In-house 1-270 (359) Show / Hide
Range on Protein: 205-409
Range on HMM: 1-270/359
Sequence Identity: 23% (67 aa)

WEPADKLGQGASGTVYRADWL-----------------GQAVAVKVFK---------------------RDDVTFEREVAALVAP---HPHVLQVIGY-L
||  .|.|.||.||||.|                    |. .|.|. .                      .   ...|.  .      ||.. . .|. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

GAG-----DGDPVIVMELMR-MDLRRFLDAGGGGGAP------------FHLAVDLLLQIARG-TRFLHDHGVVHRDLKPQNVLVDFDGDDRRMVNVLLT
  |     |..  |.||.|    |. ...  .| | |             ..    . || .|   .||.|...|||.||.|.|.           | |.
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----------VKLC

DFGIARTGFD---------------SMVNDLTSLRGTPRYMAPEMMASAAAA-LGGYSRKVDVYSFGVLCSEVLTGSPPFGD
|||..    |               .|.   ... ||| .||||..     .  .||..|.|..|.| .. | .|| ||. |
DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHD

Kinase CDK-Un_e.AA TyrKc 209-463 29 2e-35 124.93 SMART 5-280 (280) Show / Hide
Range on Protein: 209-463
Range on HMM: 5-280/280
Sequence Identity: 29% (85 aa)

DKLGQGASGTVYRADWLGQAVAVKVFKRDDVT--FEREVAALVAP---HPHVLQVIGYLGAG------DGDPVIVMELMRM-DLRRFLDAGGGGGAPFHL
.||| || |.||.. |  . ||||. | |     | ||   .      ||.... .|.   .      .. . ||||.|   ||. .| . ..   .   
KKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-LCMKD

AVDLLLQIARGTRFLHDHGVVHRDLKPQNVLVDFDGDDRRMVNVLLTDFGIARTGFDS--------MVNDLT--SLR--GTPRYMAPEMMASAAAALGGY
 ..  .|||.| ..||.....||||   |.||. ..       |  .||| .| . |         .    .  . .     | |||| .       | .
LLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----NYGKF

SRKVDVYSFGVLCSEVLT-GSPPFGD---KRWLGINEVREMVDSGKRPELPAS--------CPGELRDLITRCWSADAESRPAFSEIEREL
. | ||.||||.. |..| | .|  .   .  .   ||.| |..|.|.. |..        || |. .....|| .|.|.|| |||| ...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase CDK-Un_e.AA TK-Unique 205-463 26 1.2e-34 116.91 In-house 1-294 (294) Show / Hide
Range on Protein: 205-463
Range on HMM: 1-294/294
Sequence Identity: 26% (81 aa)

WEPADKLGQGASGTVYRADWLG--------QAVAVKVFK-------RDDVTFEREVAALVAPHPHVLQVIGYLGAGDGDPVIVMELMRMD-LRRFLDAGG
 |  |..|.|| |.|.|..  |        . ||||  |       ..| . | ..   . .||...| .|.    |... |.|| ...  |. .|   .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

GG--GA----------------------PFHLAVDLLLQIARGTRFLHD--HGVVHRDLKPQNVLVDFDGDDRRMVNVLLTDFGIARTGFDSMVNDLTSL
..  .                         .. .  . |||.|  .|.   ...|||||   |||.          .. ..|||.|| . .  |.. .  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE------DKVCKICDFGMARDVYTNGVYSMMCS

RGTP--RYMAPEMMASAAAALGGY-SRKVDVYSFGVLCSEVLT-GSPPFGDKRWLGINEVREMVDSGKRPELPASC-PGELRDLITRCWSADAESRPAFS
.|.   |.|||| .  .    | | . | ||.|||||  |..| |..|... .|     ..|..  |.|...|..| . |.. |. .||. ..|.|| |.
QGRIPIRWMAPESLKCY---HGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKD---IMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFR

EIEREL
.|  .|
QIKHRL

Kinase CDK-Un_e.AA RIPK 300-463 28 3.2e-34 114.01 In-house 112-290 (290) Show / Hide
Range on Protein: 300-463
Range on HMM: 112-290/290
Sequence Identity: 28% (54 aa)

LLLQIARGTRFLHDHG--VVHRDLKPQNVLVDFDGDDRRMVNVLLTDFGIARTGFDSMVND----------LTSLR--GTPRYMAPEMMA-SAAAALGGY
.. .|..|  .||. .  . ||||||.|.||| .       .| . ||| |     | ...           .|.   ||  ||.||.   . ....   
MIHEISCGMCYLHSMNPPIIHRDLKPENILVDNN------FHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVV

SRKVDVYSFGVLCSEVLTGSPPFGDKRWLGINEVREMVDSGKRP---ELPASCP-----GELRDLITRCWSADAESRPAFSEIEREL
. | |||||...  ||||.  |. |.    . ...  ...|.||   ..| ..|      .. .|..|||..|...||.| |.| . 
TPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMC--CKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT

Kinase CDK-Un_e.AA UTK 205-463 27 2.6e-32 107.86 In-house 1-296 (296) Show / Hide
Range on Protein: 205-463
Range on HMM: 1-296/296
Sequence Identity: 27% (85 aa)

WEPADKLGQGASGTVYRADWLG-------QAVAVKVFK-RDDVTFERE-------------VAALVAPHPHVLQVIGYLGAGDGDPVIVMELMR-MDLRR
 .. ..||||| |.|..|..         ..||||| . ..| ..|.|             . . .. ||.||...|.  .. . . ||.|.|.  ||| 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRS

FLDAGGG--GGAPFHLA----VDLLLQIARGTRFLHDHGVVHRDLKPQNVLVDFDG-DDRRMVNVLLTDFG---IARTGF---------DS-MVNDLTSL
.|   .   ...|..|     ..  ..||||  .|| .|.|||||  .|.||. .. .  .|  . . |||    .|            .| ...     
YLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQD

RGTPRYMAPEMMASAAAALGGYSRKVDVYSFGVLCSEVLT-GSPPFGDKRWLGINEVREMVDSG--KRPELPASCPGELRDLITRCWSADAESRPAFSEI
| . | |||| .....     ...| ||.||||.| |..| |. |...   ..  .| . |  |   |.. |..|| .. .| .||| .| . || | ..
RWPIRWMAPEALTHHT----RFTTKSDVWSFGVVCWEIWTWGRLPYPG---MSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDL

EREL
. ..
VQQM

Kinase CDK-Un_e.AA LRRK 205-237 24 1.5e-07 22.81 In-house 1-62 (351) Show / Hide
Range on Protein: 205-237
Range on HMM: 1-62/351
Sequence Identity: 24% (15 aa)

WEPADKLGQGASG-TVYRADWLG----------------------------QAVAVKVFKRD
 .   ..|.|..| .||||.| |                            | ||.|...||
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRD

Kinase CDK-Un_e.AA APH 207-274 15 0.000541 14.5 Pfam 1-78 (248) Show / Hide
Range on Protein: 207-274
Range on HMM: 1-78/248
Sequence Identity: 15% (12 aa)

PADKLGQGASGTVYRADWLGQ-AVAVKVFKRD----DVTFEREVAALVAPH-P--HVLQVIGY--LGAGDGDPVIVME
 .  .. |.|. .|.    ..  . .... ..    .. .|.......|.| .  .| .|...  .. . |.|. .||
WWRPISGGWSNRTYYRTTDDRPRYVLRRYPPPWWAEELHREHRWLRHLAAHGIPVPVPRVLWGCTDDEFHGWPWYLME

Kinase CDK-Un_e.AA RIPK 211-222 41 0.007923 5.43 In-house 1-12 (290) Show / Hide
Range on Protein: 211-222
Range on HMM: 1-12/290
Sequence Identity: 41% (5 aa)

LGQGASGTVYRA
.| |..|.|..|
VGGGGFGEVFKA

Kinase CDK-Un_e.AA APH 315-335 31 0.10538 6.69 Pfam 171-192 (248) Show / Hide
Range on Protein: 315-335
Range on HMM: 171-192/248
Sequence Identity: 31% (7 aa)

GVVHRDLKPQNVLVD-FDGDDR
...|.|..| ||..|  ....|
CWCHGDFHPGNVMWDPRPDGGR