Gene CAMKL-Un-2 (S.moellendorffii)

CAMKL-Un-2

Species: S.moellendorffii
Alias: CAMKL-Un-2
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
CAMKL-Un-2.AA Protein None 616 None Fasta, JSON
CAMKL-Un-2.NA RNA None 1851 None Fasta, JSON
CAMKL-Un-2.kin_dom Protein Kinase Domain None 60 None Fasta, JSON

Protein domain

Protein domains of CAMKL-Un-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CAMKL-Un-2.AA C8 468-548 24 5.4e-10 30.99 In-house 134-226 (226) Show / Hide 
Range on Protein: 468-548
Range on HMM: 134-226/226
Sequence Identity: 24% (23 aa)

EAVRALHHCKVFHRDIKPSNFIVMEHGTANQRLVLNDFDCAAHWDDSM----TEE---VGTVMFRSPVFDEG-----GEYCCRDDWLSLGLSF
. |  .|  .. ||||||.|| | . .. .    | ||. |..  ..     . .   .||  .  |   ..      .|  . |  |.||  
DGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Pkinase CAMKL-Un-2.AA Pkinase 459-527 23 1.4e-09 34.92 Pfam 110-180 (293) Show / Hide 
Range on Protein: 459-527
Range on HMM: 110-180/293
Sequence Identity: 23% (17 aa)

IAKCWREASEAVRALHHCKVFHRDIKPSNFIVMEHGTANQRLVLNDFDCAA---HWDDSMTEEVGTVMFRSP
. .....  ...  .| ... |||.||.|. . ..|. . .. . || .|.   .  .|||  .||  ...|
CKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAP
S_TKc CAMKL-Un-2.AA S_TKc 370-607 14 1.2e-07 -64.8 SMART 1-231 (231) Show / Hide 
Range on Protein: 370-607
Range on HMM: 1-231/231
Sequence Identity: 14% (40 aa)

VQVLSVLASGPRSCVFATAGLA----SVVKVSSENYIELDIRAHFWGHSSDCRYLRKMIGHGRVNGAGRGLRFVEMEGVGV---PFSKKHVS--------
 ..| .. .|  ..|.            .|. . . |.  |. .   .. .. .. |.... .      .  .. || ..       .  ..        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-EHIRREIQIL---KK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

--NAERIAKCWREASEAVRALHHCKVFHRDIKPSNFIVMEHGTANQRLVLNDFDCAAHWDDSMTEEVGTVMFRSP-VFDEGGEYCC-RDDWLSLGLSFAY
  .  ....  ..  .|.  .|  .. |||.||.|  . |      .. . ||  |..     |  .||  ...| |.     | . . || |.|  .. 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

LLG---IFPERLRWNRQWKLQILQELAVHALVPADMKTTILLALGKEHV---CCCRVVQ-------CGFL
.|     ||          .| . .. .    . ..|  |   | |.      .  . |         ..
MLCGYPPFP---------QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CAMKL-Un-2.AA Meta 473-494 54 1.6e-07 17.7 In-house 139-160 (287) Show / Hide 
Range on Protein: 473-494
Range on HMM: 139-160/287
Sequence Identity: 54% (12 aa)

LHHCKVFHRDIKPSNFIVMEHG
||. |. ||||||||  . . |
LHYQKIIHRDIKPSNLLLNDDG
Kinase CAMKL-Un-2.AA CDC7 469-488 55 5.6e-07 15.32 In-house 120-139 (522) Show / Hide 
Range on Protein: 469-488
Range on HMM: 120-139/522
Sequence Identity: 55% (11 aa)

AVRALHHCKVFHRDIKPSNF
|.| .|.  . |||.|||||
ALRHVHQFGIIHRDVKPSNF
Kinase CAMKL-Un-2.AA Ciliate-C8 468-548 20 9.1e-07 20.64 In-house 130-238 (238) Show / Hide 
Range on Protein: 468-548
Range on HMM: 130-238/238
Sequence Identity: 20% (22 aa)

EAVRALHHCKVFHRDIKPSNFIVMEHGTANQRLVLND------FDCAAHWDDSMT----------EEV------GTVMFRSPVFDEG------GEYCCRD
. |  ||   . ||||||.|| | .  . .    | |      |. |..  .. .          ...      |.. .  |   ..        .. . 
DSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSKKS

DWLSLGLSF
|  |.|| .
DSYSVGLVL
Kinase CAMKL-Un-2.AA MEK1 477-547 38 3e-06 16.88 In-house 118-185 (297) Show / Hide 
Range on Protein: 477-547
Range on HMM: 118-185/297
Sequence Identity: 38% (28 aa)

KVFHRDIKPSNFIVMEHGTANQRLVLNDFDCAAHWDDSMTEE-VGTVMFRSPVFDEGGEYCCRDDWLSLGLS
|..|||.|||| .|  .|     . | ||  .    |||    |||  . ||   .|  |  . |  |.|||
KIMHRDVKPSNILVNSRG----EIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYTVQSDIWSMGLS
Kinase CAMKL-Un-2.AA TKL 464-527 16 4e-06 17.93 In-house 139-242 (364) Show / Hide 
Range on Protein: 464-527
Range on HMM: 139-242/364
Sequence Identity: 16% (17 aa)

REASEAVRALHHCK--------VFHRDIKPSNFIVMEHGT----------ANQRLVLNDFDCAAHW----DDSMTE------------------EVGTVM
.... ..  || ..        . |||.|..|  | |..|          |. .. . ||  .  .    ....|.                  ..||  
LDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPR

FRSP
. .|
WMAP
Kinase CAMKL-Un-2.AA Trio 468-505 43 9e-06 10.05 In-house 106-143 (258) Show / Hide 
Range on Protein: 468-505
Range on HMM: 106-143/258
Sequence Identity: 43% (17 aa)

EAVRALHHCKVFHRDIKPSNFIVMEHGTA-NQRLVLNDF
|||. || | . | ||||.| . |.|. |  ... . ||
EAVHYLHNCHILHLDIKPEN-MMMWHYNAGRPQIKICDF
Kinase CAMKL-Un-2.AA nmo 473-553 38 1.5e-05 12.36 In-house 118-199 (292) Show / Hide 
Range on Protein: 473-553
Range on HMM: 118-199/292
Sequence Identity: 38% (33 aa)

LHHCKVFHRDIKPSNFIVMEHGTANQRLVLNDFDCAAHWDDS----MTEEVGTVMFRSPVFDEGG-EYCCRDDWLSLGLSFAYLLG
||  .. |||||| | .|     .|  | . ||  |  |.      ||.|| |  .| |    |   |    |  | |  || |||
LHSANILHRDIKPGNLLVN----SNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAELLG
Kinase CAMKL-Un-2.AA CDC2 468-487 40 2.2e-05 11.95 In-house 114-133 (301) Show / Hide 
Range on Protein: 468-487
Range on HMM: 114-133/301
Sequence Identity: 40% (8 aa)

EAVRALHHCKVFHRDIKPSN
..|  .|. ...|||.||.|
QGVHFCHQRRIMHRDLKPQN
Kinase CAMKL-Un-2.AA MLK 480-527 28 2.8e-05 14.42 In-house 150-202 (291) Show / Hide 
Range on Protein: 480-527
Range on HMM: 150-202/291
Sequence Identity: 28% (15 aa)

HRDIKPSNFIVME--HGTANQRLVLNDFDCAAHWDDS---MTEEVGTVMFRSP
|||.|..|  ..|  |  ..  |. .||. .  | ..   |.   ||. ...|
HRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAP