Gene CAMK1c-S3_g (S.moellendorffii)

CAMK1c-S3_g

Species: S.moellendorffii
Alias: CAMK1c-S3_g
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S3_g.AA Protein None 691 None Fasta, JSON
CAMK1c-S3_g.NA RNA None 2076 None Fasta, JSON
CAMK1c-S3_g.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S3_g.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CAMK1c-S3_g.AA S_TKc 188-444 27 2.5e-62 214.31 SMART 1-231 (231) Show / Hide 
Range on Protein: 188-444
Range on HMM: 1-231/231
Sequence Identity: 27% (74 aa)

YDVGFELGKGGQGTVHLVSFRMGGKLLAAKSFERSGEREKEIMLKLNGCHGTLEIYDMVEEERKGRWWGSLILELCSC---TLRDRLKMVGR------LA
|... ..|||. |.|...  .  |.. | |   .. .|| .|. |  ..     .||. ..   .. .  ...|.|.    .|.|..|  ||      . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK--HHPNIVKLYDVFQD---DHLY--MVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

DDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDRADEMHHLCGTPGYMSPDVLRAGEGGWPKYYTQ-AVDVWGLGLILY
  .|.|... ... |  .|..|..||| | ||.||..     ..|..|||.|.      ...|||| ||.| ||          |.  ..|.| .| |||
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL----TTFCGTPWYMAPEVL---------GYGKCKCDWWSCGCILY

ELVSGRVAFPEYHSDYVELLLKSVDNVEFALDWSDVLSEAKDLIMGMLEVYPSRRLTVEQVLG-------HPWI
|...|.  ||    .. ... | .             .||||.|...|.. |..|.|. ..|        |||.
EMLCGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CAMK1c-S3_g.AA CAMK 193-444 19 9.4e-61 194.18 In-house 1-425 (425) Show / Hide 
Range on Protein: 193-444
Range on HMM: 1-425/425
Sequence Identity: 19% (81 aa)

ELGKGGQGTVHLVSFRMGG------------KLLAAKSFERSG-----------------------------------EREKEIMLKLNG------CHGT
.||.|. |.|.|.  .  .            .  |.|  ...                                    .|| ||| ||.|          
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LEIYDMVEEERKGRWW----------------GSLIL---ELCSCT-----LRDRLKMV---------------GRLADDEAAFVTKSLAETLREMHNLG
. .|.. | ....                     ...   |.||       | |...                 ||.  .||... . ... .. .|...
IKLYEVYEDPHYFK-NTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDMKLENVLLTHPA--QP------------YEVKLSDFGVATDRAD--------------------------EMHHLCGTPGYMS-PDVLRA-GEGG
.|||| |.||.||..    ..            . .|..||| |.   .                           |.  ||||.||. | ||.  | . 
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

W-------PKYYTQAVDVWGLGLILYELVSGRVAFPEYHSD----------YVELLLKSVDNVEFALDWSDVLS-----------------------EAK
.        .||....|.| .| ||| ...|.  | . . .            . |.. . . ..  ... .                         |.|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLIMGMLEVYPSRRLTVEQVLGHPWI
||| .||.| |..|.|.||.| |||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase CAMK1c-S3_g.AA Pkinase 188-444 27 2.6e-51 181.58 Pfam 1-293 (293) Show / Hide 
Range on Protein: 188-444
Range on HMM: 1-293/293
Sequence Identity: 27% (83 aa)

YDVGFELGKGGQGTVHLVSFRMGGKLLAAKSFERSGEREKE-----------IMLKLNGCHGTLEIYDMVEEERKGRWWGSLILELCSC-----TLRDRL
| .|  .|.|. |.| .   .  ||. | | .....|....           ||..|| ..  ...||..|.  |.. .  ...|.| .      | |..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNI-VRLYDWFED--KDHIY--MVMEYCEGGLYVMDLFDYI

K--MVGRL--ADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPAQP-YEVKLSDFGVA----TDRADEMHHLCGTPGYMSPDVLRAGEGGWPKY
.  . |..   ..|. |. . ... |  .|. |..|||.|.||.|. .  ..   ||..|||.|    . .   |...||||.||.| |.|       .|
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-----GGQY

YTQAVDVWGLGLILYELVSGRVAFP------EYHSDYVELLLKSVDNVEFALD-WSDVL-----------------SEAKDLIMGMLEVYPSRRLTVEQV
|...||.|..|.||||...||  ||      . |.... . ..    ..|  . |...                  .|.||.| ..|.. |..|.| ||.
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

LGHPWI
| |||.
LQHPWF
Kinase CAMK1c-S3_g.AA AGC 296-444 20 2.1e-43 108.92 In-house 169-395 (395) Show / Hide 
Range on Protein: 296-444
Range on HMM: 169-395/395
Sequence Identity: 20% (50 aa)

MHN-LGVVHRD-MKLENVLLTHPAQPYEVKLSDFGVATD-----------------------------------------------------RADEMHHL
.|. .|..||| .|.||.||..      .||.||| ..                                                        |  . .
LHSHMGIIHRDYLKPENILLDED---GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTF

CG--TPGYMSPDVLRAGEGGWPKYYTQAVDVWG--LGLILYELVSGRVAFPEYHSD-------YVELLLKSVDNVEFALDWSDVLS--------------
||  || ||.| .|          |..|.| |.  || ..||...|.  |     .         . . ... | .... |   .               
CGPCTPEYMAPEIL----------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFS

-EAKDLIMGMLEVYPSRRLT----------VEQVLGHPWI
 |||||| ..|.. |..||.          .|..  ||| 
PEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase CAMK1c-S3_g.AA Ciliate-E2 258-444 22 3.1e-42 142.76 In-house 111-365 (365) Show / Hide 
Range on Protein: 258-444
Range on HMM: 111-365/365
Sequence Identity: 22% (61 aa)

LILELCSC-TLRDRLK------------MVGRLADDEAAFVTKSLAE---------------TLREMHNLG-VVHRDMKLENVLLTHPAQPYEVKLSDFG
|..|.|.  .|.|..|              ... . |.....| ...                |...|. . ..||| |.||.|.        .|..|||
LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--------IKIIDFG

VATDRADE----------------------------------MHHLCGTPGYMSPDVLRAGE-----GGWPKYYTQAVDVWGLGLILYELVSGRVAFPEY
 ...  |.                                   . .|||||||.| .|. ..     ..  |.|. ..|.| || ||||...|.  |   
LSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQ--KGYDYKCDIWSLGVILYEMLFGKPPF---

HSDYVELLLKSVDNVEFALD---------------WSDVLSEAKDLIMG----MLEVYPSRRLT-VEQVLGHPWI
      .  .   ...|                  | ..  |.||||      ||.. |. |.|  ||.| |||.
------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CAMK1c-S3_g.AA CAMKL 258-444 28 2.1e-39 123.34 In-house 98-297 (297) Show / Hide 
Range on Protein: 258-444
Range on HMM: 98-297/297
Sequence Identity: 28% (60 aa)

LILELCSCT---LRDRLKMV----GRLADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPA-QPYEVKLSDFGVATD-RA-----DE-MHHLCG
|..|.||     | |...      ||.  .|| .  . . . .  .|..|.|||| |.||.||..   .   .|..||| ..  |      .. ..  ||
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCG

TPGYMSPDVLRAGEGGWPKYYTQAVDVWGLGLILYELVSGRVAFPEYH------SDYVELLLKSVDNVEFALDWSDVLSEAKDLIMGMLEVYPSRRLTVE
.| ||.| ..  .     .|. ..||.| .| ||| .| |.. | . .      ... .|..|     ..   |..|  ...||| .||.| |..| |..
SPPYMAPEIFQGN---NKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIH

QVLGHPWI
|.. ||| 
QIMNHPWM
Kinase CAMK1c-S3_g.AA MSK 270-444 29 2.5e-38 127.14 In-house 91-277 (277) Show / Hide 
Range on Protein: 270-444
Range on HMM: 91-277/277
Sequence Identity: 29% (57 aa)

RLKMVGRLADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDRADE----MHHLCGTPGYMSPDVLRA---GEGGWPKY
...  ..   .|....  .|   .. || .|..|||.|.||.|..      .|||.||| |  .  .    |.  |.|  ||.|..||    ..||    
HIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGG----

YTQAVDVWGLGLILYELVSGRVAFPEYHSDYV------ELLLKSVDNVEFALD---WSDVLSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
| .|.|.|.|| |||.. .|.| |    .|          . | .   || ..   |. .  .||||| ..|.. |..||...  . | |.
YDEACDWWSLGVILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase CAMK1c-S3_g.AA RSK 269-444 27 2.8e-38 133.51 In-house 90-278 (278) Show / Hide 
Range on Protein: 269-444
Range on HMM: 90-278/278
Sequence Identity: 27% (54 aa)

DRLKMVGR---LADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTH-PAQPYEVKLSDFGVATD-RAD---EMHHLCGTPGYMSPDVLRAGEGGWP
..|.  ..   .  |||.|.   .. ... .| .|..||| |.||.|...   .. ..||.||| .   |.|    ..  |.|  || | .|. ..   .
THLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN--QQ

KYYTQAVDVWGLGLILYELVSGRVAFPEYHSD-YVELLLKSVDNVE--FALD-WSDVLSEAKDLIMGMLEVYPSRRLT-----VEQVLGHPWI
. ...|.|.| || ..||. .|.. |     |   . ..| . . .  . .. |. .  |||||| .||.. |..||.     .|... |||.
GGHDKACDWWSLGVLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CAMK1c-S3_g.AA DCAMKL 269-444 33 6.7e-37 111.95 In-house 104-279 (279) Show / Hide 
Range on Protein: 269-444
Range on HMM: 104-279/279
Sequence Identity: 33% (62 aa)

DRLKMVGRLADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTH-PAQPYEVKLSDFGVATDRAD---EMHHLCGTPGYMSPDVLRAGEGGWPKYYT
| .  ...    .||  .  |.. |. .| ...|||| |.|| |.   .    ..|| ||| |.   .    .   |||| |  | .|.  | |    | 
DAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILM--ETG----YG

QAVDVWGLGLILYELVSGRVAFPEYHSD--YVELLLKSVDNVEFALD---WSDVLSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
  ||.| .| ||| |  |   ||   |     | | . .   .| ..   |... . |||||  ||.| | .| | ||.. |||.
CKVDIWAAGVILYILLCG---FPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CAMK1c-S3_g.AA STE 258-444 20 3.1e-31 107.57 In-house 114-359 (359) Show / Hide 
Range on Protein: 258-444
Range on HMM: 114-359/359
Sequence Identity: 20% (53 aa)

LILELCSC-TLRDRLKMV--------------GRLADDEAAFVTKSLAET-LREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDRAD------
...|...  .|.| .| .              .|.  .. |...... .  |   |.....||| |  |.||        |||.||||..  .|      
ICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLCDFGVCGQLTDSMANIQ

-------------EMHHLCGTPGYMSPDVLRAGEGGWP-KYYTQAVDVWGLGLILYELVSGRVAFPEYHSDYVELLLKSV---------------DNVEF
             .  ...||| .|.| |.. ...|   | |.  .|.| ||. . |.. |.. . ..|  .. ..                   .   .
SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPL

ALDWS----------------DVLSEAKDLIMGMLEVYPSRRLTVEQVLG--HPWI
  . |                 . .| || |   |.  |. | |..| |   ||.|
PDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase CAMK1c-S3_g.AA Ciliate-E2a 258-387 32 1.5e-28 81.19 In-house 76-217 (275) Show / Hide 
Range on Protein: 258-387
Range on HMM: 76-217/275
Sequence Identity: 32% (47 aa)

LILELCSC-TLRDRLKMVGRLADD--EAAFVTKSLA-ETLREMHNLGVVHRDMKLENVLLT--HPA--QPYEVKLSDFGVATDR--ADE--MHHLCGTPG
|..|.|.  .| |..|  .|.     |.. . . |  . |  ||.....||| |.||.|..   .   |. ..|..||| ||.    ..  |.  |||||
LVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPG

YMSPDVLRAGE--GGWPKYYTQAVDVWGLGLILYELVSGRVAFP
|. | ||   |   .  | |.. .|.| .|.|.| |..|.  |.
YVAPEVLNNKEVLKH--KQYDTKCDMWSCGVIFYILLCGKPPFK
Kinase CAMK1c-S3_g.AA CAMK1 296-377 39 8.6e-25 68.95 In-house 124-207 (276) Show / Hide 
Range on Protein: 296-377
Range on HMM: 124-207/276
Sequence Identity: 39% (34 aa)

MHNLGVVHRDMKLENVLLTHPAQPYEVK--LSDFGVATDRA-D--EMHHLCGTPGYMSPDVLRAGEGGWPKYYTQAVDVWGLGLILY
|| .|.|||| | || |.  .    ..|  ..||| ..    |   |   ||||||. |.||   .   .| | .|.|.|. | |.|
MHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK---DKPYDKACDMWSIGVITY
Kinase CAMK1c-S3_g.AA CAMK1 410-444 52 1.7e-16 44.4 In-house 241-276 (276) Show / Hide 
Range on Protein: 410-444
Range on HMM: 241-276/276
Sequence Identity: 52% (19 aa)

WSDVLSE-AKDLIMGMLEVYPSRRLTVEQVLGHPWI
| .. .. |||.| .|||| |. |.|.||.| ||||
WDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CAMK1c-S3_g.AA Ciliate-E2a 409-444 43 2.6e-11 29.57 In-house 239-275 (275) Show / Hide 
Range on Protein: 409-444
Range on HMM: 239-275/275
Sequence Identity: 43% (16 aa)

D-WSDVLSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
. |... .|.|||. .|||..|. |.| .| | ||| 
ECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase CAMK1c-S3_g.AA TyrKc 188-444 17 7.4e-05 -144.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 188-444
Range on HMM: 1-280/280
Sequence Identity: 17% (52 aa)

YDVGFELGKGGQGTVHLVSFRMGGKLLAAKSFERSG----EREKEIMLKL-NGCHGTLEIYDMVEEER------KGRWWGSLILELCSC-TLRDRLKMVG
   | .|| |  |.|..   .      | |.   .      || .|| ||       . .|  . ..       .  .   ...|...   |.|.|.  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM---IVMEYMPHGDLKDYLRKHR

R-LADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDRADE--------MHHLC---GTPG-----YMSPDVLRAGEGG
. |  ..        |.  .  |  ...|||    |.|....     || |||| . |  |.        . .     |. .      |.| ... |.  
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK--

WPKYYTQAVDVWGLGLILYELVSGRVAFPEYHS-----DYVELLLKSVDNVEFALDWSD--------VLSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
    .| . |||  |  ..|. .     . |          . ... |.. .      .          .|  ...    .  |. | | ...  |  .
----FTTKSDVWSFGVCMWEIFTY--GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CAMK1c-S3_g.AA CAMKL 188-204 52 0.001067 7.51 In-house 1-17 (297) Show / Hide 
Range on Protein: 188-204
Range on HMM: 1-17/297
Sequence Identity: 52% (9 aa)

YDVGFELGKGGQGTVHL
|..| .||||. |.| |
YRIGKTLGKGSFGKVKL
Kinase CAMK1c-S3_g.AA Ciliate-E2 188-206 26 0.006192 5.89 In-house 1-19 (365) Show / Hide 
Range on Protein: 188-206
Range on HMM: 1-19/365
Sequence Identity: 26% (5 aa)

YDVGFELGKGGQGTVHLVS
|..   .|.|..|.| ...
YKFIKKIGQGNFGSVYKCK