CAMK1c-S2_b

Species: S.moellendorffii
Alias: CAMK1c-S2_b
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S2_b.AA Protein None 186 None Fasta, JSON
CAMK1c-S2_b.NA RNA None 561 None Fasta, JSON
CAMK1c-S2_b.kin_dom Protein Kinase Domain None 182 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S2_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase CAMK1c-S2_b.AA Pkinase 1-182 21 3e-27 97.41 Pfam 90-293 (293) Show / Hide
Range on Protein: 1-182
Range on HMM: 90-293/293
Sequence Identity: 21% (46 aa)

SLQDRIK--YKGQL--DEEESTKIVIALAKTLKRVHDNEIIHCDVKPMNVLLKYPQPGKFYVP----KLSDFGMAC---WMEDLWNERGVGTWDYMSPEA
.| |.|.  ..| .  .|.|  ...  ... |.  |.. |||.|.|| |.|..       ...    |..||| |.   .  .  .   .|| .||.|| 
DLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNN-----GHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV

ML-DGHYIAGSDVWGLGMLLYTCLMGTCLFPNL-------DLEVVFKNAHKRDRSTRNFHHNSMDWDSIPS-----------HSARQLIQGTMELDPGRR
 . . .|   .|.|..| .||  | |  .||.        ........ ... .. .   .. ..   ..             .....| .  ..|| .|
IRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRHWHFHWTFHNWSEECKDFIKWCLCKDPKKR

FTLENVLDHEWI
 | | .| |.|.
PTAEQILQHPWF

Kinase CAMK1c-S2_b.AA CAMK 2-182 17 4.3e-24 73.9 In-house 151-425 (425) Show / Hide
Range on Protein: 2-182
Range on HMM: 151-425/425
Sequence Identity: 17% (48 aa)

LQDRIKYKGQ---------------LDEEESTKIVIALAKTLKRVHDNEIIHCDVKPMNVLLKYPQP------------GKFYVPKLSDFGMACWMEDLW
| |.|. .|.               ..|.|  ...  ..  ..  |.. |.|.| || |.|| .  .            .. .  |..|||.|. ...  
LFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGE

NER-------------------------GVGTWDYMS-PEAMLD-------------GHYI-AGSDVWGLGMLLYTCLMGTCLFPNLDLEVVFKNAHKRD
|..                          .||  ||. ||  .                |.   .|.| .| .||..| |.  |   . .  ..   .  
NNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D-E--

R---STRNFHHN--SMDWDSIPSH--------------------------SARQLIQGTMELDPGRRFTLENVLDHEWI
.   . .. ...  . ..| .|..                          ....||.. .. || .|.|.| .|.|.|.
WIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase CAMK1c-S2_b.AA Ciliate-E2 1-182 19 1.5e-23 77.66 In-house 120-365 (365) Show / Hide
Range on Protein: 1-182
Range on HMM: 120-365/365
Sequence Identity: 19% (51 aa)

SLQDRIK------------YKGQLDEEESTKIVIALAK---------------TLKRVHDNE-IIHCDVKPMNVLLKYPQPGKFYVPKLSDFGMA-----
.|.|.||            . ....|.|  .|   ...                |.  | .  ||| | || |.|.          .|..|||..     
DLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----------IKIIDFGLSKKYDD

-------CWMEDLWNERG----------------------VGTWDYMSPEAMLDGH---------YIAGSDVWGLGMLLYTCLMGTCLFPNLDLEVV---
       . .  .. . .                      .||  ||.||    .          |   .|.| ||..|| .|.|   |  ..       
DNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--QQQIKQCKI

-FKNAHKRDRSTRNFHHNSMDW--DSIPSHSARQLIQG----TMELDPGRRFT-LENVLDHEWI
 | ....... |        .|      | .. .||.      .. ||  |.|  | .|.|.|.
DFPCPEWQKD-TQ-CI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase CAMK1c-S2_b.AA Ciliate-E2-Unclassified 2-182 20 9.6e-22 72.22 In-house 125-352 (352) Show / Hide
Range on Protein: 2-182
Range on HMM: 125-352/352
Sequence Identity: 20% (48 aa)

LQDRIKYKGQLDEEEST-----KIVIALAKTLKRVHDNE-IIHCDVKPMNVLLKYPQPGKFYVPKLSDFGMA------------------CWMEDLWNER
| ...|.. ...|...      ..   . . |.  | .  ||| | || |.|..  .    | .|..||| .                   | ... . .
LFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK--NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTF

GVGTWDYM----SPEAMLDGHYI----AGSDVWGLGMLLYTCLMGTCLFPNLDLEV----------------VFKNAHKRDRSTRNFHH--NSMDWDSIP
 .||  ||    .|| .   .|       .|.|.||..|| .|.|.. |.  . |                 ...| .... . ..| .   ...|.   
-CGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEA

SHSARQLIQGTMELDPGRRFTLENVLDHEWI
 .  ..|.|  .. .|. | |.| .| | |.
KDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase CAMK1c-S2_b.AA CAMKL 1-182 20 9.2e-21 62.85 In-house 107-297 (297) Show / Hide
Range on Protein: 1-182
Range on HMM: 107-297/297
Sequence Identity: 20% (41 aa)

S--LQDRIKYKGQ----LDEEESTKIVIALAKTLKRVHDNEIIHCDVKPMNVLLKYPQ-PGKFYVPKLSDFGMACWMED--LWNER----GVGTWDYMSP
.  |.|.|. .|     ..|.|  ..   .   ..  |.. |.| | || |.|| . .      . |..|||.. ....   ....      |.  ||.|
EMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN----NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAP

EAMLD--GHYI-AGSDVWGLGMLLYTCLMGTCLFPNLDLE----VVFKNAHKRDRSTRNFHHNSMDWDSIPSHSARQLIQGTMELDPGRRFTLENVLDHE
|  ..   .|.    |.| .| .||. . |.  | . ...      . . .......  .    ..  . .| ..|.||.. .. .| .|.|..... |.
EIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YY----PPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WI
| 
WM

Kinase CAMK1c-S2_b.AA MSK 5-182 30 1.2e-20 66.56 In-house 91-277 (277) Show / Hide
Range on Protein: 5-182
Range on HMM: 91-277/277
Sequence Identity: 30% (58 aa)

RIKYKGQLDEEESTKIVIALAKTLKRVHDNEIIHCDVKPMNVLLKYPQP-GKFYVPKLSDFGMACWMEDLWNERGVG---TWDYMSPEAML-----DGHY
.|. ..  ||.|   |.  |   ..  |.  ||| | || |.|.   .. |.    ||.||| |.      ..|      | .||.||        || |
HIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHV---KLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGY

IAGSDVWGLGMLLYTCLMGTCLFP--NLDLE---VVFKNAHKRDRSTRNFHHNSMDWDSIPSHSARQLIQGTMELDPGRRFTLENVLDHEWI
 .  |.|.|| .||| | |   |     | .      .   || . . .|   .| | .. |  |. |||.  . || .| ...  ..|||.
DEACDWWSLGVILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRIC-KGEFSFPGMAWQNM-SPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK

Kinase CAMK1c-S2_b.AA ULK 8-182 22 9.3e-17 56.04 In-house 119-324 (324) Show / Hide
Range on Protein: 8-182
Range on HMM: 119-324/324
Sequence Identity: 22% (48 aa)

YKGQLDEEESTKIVIALAKTLKRVHDNEIIHCDVKPMNVLLKYPQPGK-------FYVPKLSDFGMACWMED--LWNERG---V------GTWDYMSPEA
.|. | |.|  .. . ..  .|  |.. |||.| || | |.. .||..        .| |..||| |   ..  .        |      ||  ||.|. 
EKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQI

MLDG-----HYIAGSDVWGLGMLLYTCLMGT-----CLFPNLDLEVVFKNAHKR------DRSTRNFHHNSMDWDSIPSHSARQLIQGTMELDPGRRFTL
  .      .| . .|.| ||...| .| |      . | ...|  . |  ...       . .   . .    | . |   ..||.. .. |.  |.. 
LQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPP-KDPKISPECKDLIRRMLQYDEKDRISW

ENVLDHEWI
| ...|.|.
EEIFNHPWF

Kinase CAMK1c-S2_b.AA ULK 2-182 22 7.1e-16 51.98 In-house 107-329 (329) Show / Hide
Range on Protein: 2-182
Range on HMM: 107-329/329
Sequence Identity: 22% (51 aa)

LQDRIKYKGQ----------LDEEESTKIVIALAKTLKRVHDNEIIHCDVKPMNVLLKYPQPGK-------FYVPKLSDFGMACWME-DL----WNERGV
|.. || ..           | |.|  .. . ..  .|  |.. |||.| || |.|.. .||..        .| |..||| |  .. |.     .   |
LEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCV

------GTWDYMSPEAMLDG-----HYIAGSDVWGLGMLLYTCLMGT-----CLFPNLDLEVVFKNAHKRDRS-----TRNFHHN---SMDWDSIPSHSA
      ||  ||.|.   .      .| . .|.| ||...| .| |      . |  ..|  . |.  .....     ....  .   .   | . |   
NEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGN---DPQISPEC

RQLIQGTMELDPGRRFTLENVLDHEWI
..||.. .. |.  |.. | ...|.|.
KDLIRRMLQYDEKDRISWEELFNHPWF

Kinase CAMK1c-S2_b.AA RSK 2-182 22 1.4e-14 50.07 In-house 88-278 (278) Show / Hide
Range on Protein: 2-182
Range on HMM: 88-278/278
Sequence Identity: 22% (45 aa)

LQDRIKYKGQ---LDEEESTKIVIALAKTLKRVHDNEIIHCDVKPMNVLLKYPQPGKFYVPKLSDFGMACWM---EDLWNERGVGTWDYMSPEAML----
| .... ...   ..|.|   .   ......  |.  ||| | || |.|.   . .   . ||.||| .. .   .  |    ..| .|| ||       
LFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHI-KLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQ

DGHYIAGSDVWGLGMLLYTCLMGTCLFPNLDLEVVFKNAHKRDRSTRNFH--HNSMDWDSIPSHSARQLIQGTMELDPGRRFT-----LENVLDHEWI
.| . .  |.| || |.|. |.|   | . .     .|...  .  .. .   ... |... |. |. ||.. .. || .| .     .| ...|.|.
QGGHDKACDWWSLGVLMYEMLTGCPPFQG-PND---NNRKEIMKRIQKGKFSLTMPNWQYL-SQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase CAMK1c-S2_b.AA CAMK-Unique 7-114 21 2.4e-14 43.55 In-house 147-289 (363) Show / Hide
Range on Protein: 7-114
Range on HMM: 147-289/363
Sequence Identity: 21% (31 aa)

KYKGQLDE--EESTKIVIALAKTLKRVHDNEIIHCDVKPMNVLLKYP-Q--------PGK--FYVPKLSDFGMACWMEDLWNE----RGVGTWDYMSP--
. .|.. |   ... |.  |.  ..  |.. |.| | |. |....|. .        |..  ..  ||.|||..|  .    .      .|| .||.|  
RCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEI

-----------EAMLD-GHYIAGS----DVWGLGMLLYTCLMG
           .....   |   .    | | || ..|. | |
VFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCG

Kinase CAMK1c-S2_b.AA S_TKc 1-182 18 2e-12 5.29 SMART 1-231 (231) Show / Hide
Range on Protein: 1-182
Range on HMM: 1-231/231
Sequence Identity: 18% (50 aa)

S--------------------------------------------------------------------------LQDRIKYKGQ------LDEEESTKI
                                                                           | |.|| .|       ..| .  ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

VIALAKTLKRVHDNEIIHCDVKPMNVLLKYPQPGKFYVPKLSDFGMACWMEDLWNERGVGTWDYMSPEAMLDGHYIA-GSDVWGLGMLLYTCLMGTCLFP
.  ... |.  |.. |||.|.|| |.||         . |..|||.|. .        .|| .||.|| .   .|    .|.| .| .|| .| |  .||
MYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP

NLDLEVVFKNAHKRDRSTRNFHHNSMDWDSIPSHSARQLIQGTMELDPGRRFTLENVLD-------HEWI
  .....||.                      |..|...|.. .. || .| |   .|        |.|.
--QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase CAMK1c-S2_b.AA DCAMKL 2-114 32 4.5e-12 33.29 In-house 102-215 (279) Show / Hide
Range on Protein: 2-114
Range on HMM: 102-215/279
Sequence Identity: 32% (38 aa)

LQDRIKYKGQLDEEESTKIVIALAKTLKRVHDNEIIHCDVKPMNVLLKYPQPGKFYVPKLSDFGMACWMED----LWNERGVGTWDYMSPEAMLDGHYIA
| | |   .   | ..  ..  |.| ||  |.  |.| |.|| | |..  . |.. . || ||| || ...    |.  .  ||  |  || .    |  
LFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSL-KLCDFGLACHVNGDFGPLY--TVCGTPTYVAPEILMETGYGC

GSDVWGLGMLLYTCLMG
  |.| .|  ||  | |
KVDIWAAGVILYILLCG

Kinase CAMK1c-S2_b.AA DCAMKL 147-182 41 3.6e-10 27.27 In-house 245-279 (279) Show / Hide
Range on Protein: 147-182
Range on HMM: 245-279/279
Sequence Identity: 41% (15 aa)

WDSIPSHSARQLIQGTMELDPGRRFTLENVLDHEWI
|| | | ||. ||.  .. || .|.| | ...| |.
WDNI-SDSAKDLISHMLQVDPEKRYTAEQIMQHPWV

Kinase CAMK1c-S2_b.AA CAMK-Unique 152-182 32 6.1e-09 25.44 In-house 333-363 (363) Show / Hide
Range on Protein: 152-182
Range on HMM: 333-363/363
Sequence Identity: 32% (10 aa)

SHSARQLIQGTMELDPGRRFTLENVLDHEWI
| .| ......|..||  | .... |.|.||
SQEAKDFVKCCMTVDPDHRWSAKELLEHQWI