Gene CAMK1c-S1_g (S.moellendorffii)
CAMK1c-S1_g
Species: S.moellendorffii
Alias: CAMK1c-S1_g
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
CAMK1c-S1_g.AA | Protein | None | 315 | None | Fasta, JSON |
CAMK1c-S1_g.NA | RNA | None | 948 | None | Fasta, JSON |
CAMK1c-S1_g.kin_dom | Protein Kinase Domain | None | 168 | None | Fasta, JSON |
Protein domains of CAMK1c-S1_g.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
---|---|---|---|---|---|---|---|---|---|
Kinase | CAMK1c-S1_g.AA | CAMK | 163-254 | 22 | 9.9e-25 | 76.0 | In-house | 276-425 (425) | Show / Hide |
Range on Protein: 163-254 Range on HMM: 276-425/425 Sequence Identity: 22% (34 aa) MSNLAGTQMYSA-PEMVNS--------------DEYDEMVDVWGMGIVLYEILSGTI-------------------------ALCMGREDVPLSSLD--- |. || | | ||..|. . |.. .|.| .|..|| |.|. . |. | | . .. MKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPIS -------WTDVTEE--------AKDLILQLLHLNPRKRLPIHEIEKHPWV | |...| .|||| ..| .| ||. |... .|||. CNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM |
|||||||||
S_TKc | CAMK1c-S1_g.AA | S_TKc | 56-254 | 21 | 1.7e-22 | 81.97 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 56-254 Range on HMM: 1-231/231 Sequence Identity: 21% (55 aa) FSVEKELGRGGHCVQSETVLTK--------------------LSKSKERSGVVQLVDVFKDEDHYFLLMDQCQC---SLTEVLLKKKK------LSEHEA . . ...|.|. . . .| |.| .|.| ||| | ||... |. | .| ... |... ..| .| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HA AVVIKNVARTVGKMHDMGMAHRDIKTDN---------------RGPGIKFRMSNLAGTQMYSAPEMVNSDEYDE-MVDVWGMGIVLYEILSGTIALCMGR . ... ... . .|..| |||.| .| | . . || | |||.. |. .|.| |..||| |.| . RFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--Q EDVPLSSLDWTDVTEEAKDLILQLLHLNPRKRLPIHEIEK-------HPWV ... . . ..||||.| ..|. .|.||. . |. . |||. MQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||
Kinase | CAMK1c-S1_g.AA | CAMKL | 168-254 | 28 | 7.2e-20 | 59.96 | In-house | 195-297 (297) | Show / Hide |
Range on Protein: 168-254 Range on HMM: 195-297/297 Sequence Identity: 28% (30 aa) GTQMYSAPEMVNS--DEYD-EMVDVWGMGIVLYEILSGTIA--------------LCMGREDVPLSSL-DWTDVTEEAKDLILQLLHLNPRKRLPIHEIE |. | |||.... ..|| ||.| .|..|| .. |. . . .. . | .| ...||| ..| || || ||.|. GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM KHPWV .|||. NHPWM |
|||||||||
Kinase | CAMK1c-S1_g.AA | Ciliate-E2 | 165-254 | 25 | 7.7e-18 | 57.8 | In-house | 246-365 (365) | Show / Hide |
Range on Protein: 165-254 Range on HMM: 246-365/365 Sequence Identity: 25% (31 aa) NLAGTQMYSAPEMVNSDE---------YDEMVDVWGMGIVLYEILSGTI---ALCMGREDVPLSSL-------------DWTDVTEEAKDLILQ----LL ...|| .| |||..|. . ||...|.| .|..||| |.| . . . .| ....|.|||| . .| TICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPFQQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRML HLNPRKRLP-IHEIEKHPWV .| ||. . .| .||| QKDPEKRITGWEQILNHPWF |
|||||||||
Kinase | CAMK1c-S1_g.AA | Pkinase | 163-254 | 25 | 4.6e-17 | 61.43 | Pfam | 168-293 (293) | Show / Hide |
Range on Protein: 163-254 Range on HMM: 168-293/293 Sequence Identity: 25% (32 aa) MSNLAGTQMYSAPEMVN-SDEYDEMVDVWGMGIVLYEILSGTIALCMGR-----------------EDVPLSSLDWTDVT-----------------EEA |. ..|| | ||| .. . .|. ||.|..|..||| |.| .. |. ... .. | .. ||. MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR-PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEEC KDLILQLLHLNPRKRLPIHEIEKHPWV ||.| .|...| ||. ...| .|||. KDFIKWCLCKDPKKRPTAEQILQHPWF |
|||||||||
Kinase | CAMK1c-S1_g.AA | ULK | 168-254 | 22 | 5.8e-15 | 49.57 | In-house | 209-324 (324) | Show / Hide |
Range on Protein: 168-254 Range on HMM: 209-324/324 Sequence Identity: 22% (26 aa) GTQMYSAPEMVNSD----EYDEM-VDVWGMGIVLYEILSGTIA--LCMGREDV----PL-------------SSLDWTD------VTEEAKDLILQLLHL || .| ||. ... .|.. .|.| .|...||.| | . .... | ... . . .| |||| ..| GTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQY NPRKRLPIHEIEKHPWV ....| ..|| .|||. DEKDRISWEEIFNHPWF |
|||||||||
Kinase | CAMK1c-S1_g.AA | MNK | 82-154 | 33 | 7.2e-14 | 44.09 | In-house | 55-128 (292) | Show / Hide |
Range on Protein: 82-154 Range on HMM: 55-128/292 Sequence Identity: 33% (25 aa) KERSGVVQLVDVFKDEDHYFLLMDQCQ-CSLTEVLLKKKKLSEHEAAVVIKNVARTVGKMHDMGMAHRDIKTDN . ...||.. | |.| ..| . . .| ...| .|||| .|||..| ||. | ||||.| | QGHRNILQLIEWFEDDDRFYLVFEKMRGGPLLQHIQQRKHFTEHEASQVIKDIASALDFMHNKGIAHRDLKPEN |
|||||||||
Kinase | CAMK1c-S1_g.AA | CAMK-Unique | 220-254 | 26 | 1.5e-11 | 34.23 | In-house | 326-363 (363) | Show / Hide |
Range on Protein: 220-254 Range on HMM: 326-363/363 Sequence Identity: 26% (10 aa) WTD---VTEEAKDLILQLLHLNPRKRLPIHEIEKHPWV | . ...||||.. ... . | .|... |...|.|. WHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI |
|||||||||
Kinase | CAMK1c-S1_g.AA | Pkinase | 87-154 | 28 | 2.5e-11 | 41.14 | Pfam | 62-138 (293) | Show / Hide |
Range on Protein: 87-154 Range on HMM: 62-138/293 Sequence Identity: 28% (22 aa) VVQLVDVFKDEDHYFLLMDQCQC-----SLTEVLL--KKKKL--SEHEAAVVIKNVARTVGKMHDMGMAHRDIKTDN .|.| |.| |.||. . |. |.. .| ... ..... ||.|. ... ..| . .|.|| |||.| .| IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPEN |
|||||||||
Kinase | CAMK1c-S1_g.AA | Ciliate-E2-Unclassified | 162-203 | 34 | 3.5e-11 | 35.06 | In-house | 218-267 (352) | Show / Hide |
Range on Protein: 162-203 Range on HMM: 218-267/352 Sequence Identity: 34% (17 aa) RMSNLAGTQMYS----APEMVNSDEYD----EMVDVWGMGIVLYEILSGT .|. .|| .| |||. . .|| ...|.|..|..|||.| |. MMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY |
|||||||||
Kinase | CAMK1c-S1_g.AA | MSK | 172-202 | 44 | 9e-11 | 32.63 | In-house | 171-206 (277) | Show / Hide |
Range on Protein: 172-202 Range on HMM: 171-206/277 Sequence Identity: 44% (16 aa) YSAPEMVN----SDE-YDEMVDVWGMGIVLYEILSG | ||||.. .|. ||| .|.|..|..||. |.| YMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTG |
|||||||||
Kinase | CAMK1c-S1_g.AA | CAMK-Unique | 88-154 | 17 | 2.6e-10 | 30.03 | In-house | 79-187 (363) | Show / Hide |
Range on Protein: 88-154 Range on HMM: 79-187/363 Sequence Identity: 17% (19 aa) VQLVDV----FKDED---------------HYFLLMDQCQCS-LTEVLLK--------------------KKKLSE--HEAAVVIKNVARTVGKMHDMGM ..|.|. | |.. .....|. ||. | ....| . ..|| ... .. .. | ||. . IKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDI AHRDIKTDN |||.| .| VHRDLKLEN |
|||||||||
Kinase | CAMK1c-S1_g.AA | MSK | 208-254 | 29 | 2.8e-10 | 30.97 | In-house | 231-277 (277) | Show / Hide |
Range on Protein: 208-254 Range on HMM: 231-277/277 Sequence Identity: 29% (14 aa) MGREDVPLSSLDWTDVTEEAKDLILQLLHLNPRKRLPIHEIEKHPWV . ...... . |. . ..||||| .|| .| ||| .. .| | ICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK |
|||||||||
Kinase | CAMK1c-S1_g.AA | RSK | 220-254 | 45 | 2.9e-10 | 34.09 | In-house | 239-278 (278) | Show / Hide |
Range on Protein: 220-254 Range on HMM: 239-278/278 Sequence Identity: 45% (18 aa) WTDVTEEAKDLILQLLHLNPRKRLP-----IHEIEKHPWV | ...|||||| ..|| .| ||| . || .||| WQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
|||||||||
Kinase | CAMK1c-S1_g.AA | RSK | 87-154 | 31 | 3.1e-10 | 33.99 | In-house | 63-134 (278) | Show / Hide |
Range on Protein: 87-154 Range on HMM: 63-134/278 Sequence Identity: 31% (23 aa) VVQLVDVFKDEDHYFLLMDQCQ-CSLTEVLLKKKK---LSEHEAAVVIKNVARTVGKMHDMGMAHRDIKTDN .|.| ..|..|.. .| |. | |.. |.|.| .||.||.... ... .| .|. | |||.| .| IVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPEN |
|||||||||
Kinase | CAMK1c-S1_g.AA | RSK | 87-154 | 34 | 4.2e-10 | 32.49 | In-house | 63-131 (271) | Show / Hide |
Range on Protein: 87-154 Range on HMM: 63-131/271 Sequence Identity: 34% (24 aa) VVQLVDVFKDEDHYFLLMDQCQ-CSLTEVLLKKKKLSEHEAAVVIKNVARTVGKMHDMGMAHRDIKTDN .|.| .|| || . .. || .. | |||.| .|| |.. . ..|... . | | .||| | .| IVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPEN |
|||||||||
Kinase | CAMK1c-S1_g.AA | MNK | 219-254 | 44 | 1.4e-09 | 29.18 | In-house | 257-292 (292) | Show / Hide |
Range on Protein: 219-254 Range on HMM: 257-292/292 Sequence Identity: 44% (16 aa) DWTDVTEEAKDLILQLLHLNPRKRLPIHEIEKHPWV .| .. ||||||| .|| . || .. .|||| EWHHISEEAKDLISNLLVRDAKQRLSAAQVLNHPWV |
|||||||||
Kinase | CAMK1c-S1_g.AA | CAMK-Unique | 163-202 | 27 | 2.5e-09 | 26.75 | In-house | 232-289 (363) | Show / Hide |
Range on Protein: 163-202 Range on HMM: 232-289/363 Sequence Identity: 27% (16 aa) MSNLAGTQMYSAP--------------EMVNSDEYDEMV----DVWGMGIVLYEILSG |.. || .| || |..| . ||. . | | .| ..|. |.| MQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCG |
|||||||||
Kinase | CAMK1c-S1_g.AA | MSK | 87-154 | 30 | 2.9e-09 | 27.45 | In-house | 63-131 (277) | Show / Hide |
Range on Protein: 87-154 Range on HMM: 63-131/277 Sequence Identity: 30% (21 aa) VVQLVDVFKDEDHYFLLMDQCQCS-LTEVLLKKKKLSEHEAAVVIKNVARTVGKMHDMGMAHRDIKTDN .|.| ..|.|. | .| |. |. |.. . |... .|.|..... . | ||. | |||.| | IVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPEN |
|||||||||
Kinase | CAMK1c-S1_g.AA | RSK | 215-254 | 33 | 3.1e-09 | 29.34 | In-house | 227-271 (271) | Show / Hide |
Range on Protein: 215-254 Range on HMM: 227-271/271 Sequence Identity: 33% (15 aa) LSSLDWTDVTEEAKDLILQLLHLNPRKRLPI-----HEIEKHPWV ... | ...|||||. ..|| .| .|| .| .|||. MTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
|||||||||
Kinase | CAMK1c-S1_g.AA | RSK | 168-202 | 35 | 3.4e-09 | 30.11 | In-house | 170-208 (278) | Show / Hide |
Range on Protein: 168-202 Range on HMM: 170-208/278 Sequence Identity: 35% (14 aa) GTQMYSAPEMVN---SDE-YDEMVDVWGMGIVLYEILSG .| | ||||.. .. .|. .|.| |...|| |.| YTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTG |
|||||||||
Kinase | CAMK1c-S1_g.AA | CAMKL | 87-154 | 25 | 2.1e-08 | 22.75 | In-house | 77-157 (297) | Show / Hide |
Range on Protein: 87-154 Range on HMM: 77-157/297 Sequence Identity: 25% (21 aa) VVQLVDVFKDEDH------YFLLMDQCQCS---LTEVLLKK----KKLSEHEAAVVIKNVARTVGKMHDMGMAHRDIKTDN ...| .|. ...| ..| | |. | . . |. ....|||| . . | .|..| .||||| .| IIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPEN |
|||||||||
Kinase | CAMK1c-S1_g.AA | CAMK | 87-154 | 15 | 2.2e-08 | 22.35 | In-house | 100-209 (425) | Show / Hide |
Range on Protein: 87-154 Range on HMM: 100-209/425 Sequence Identity: 15% (17 aa) VVQLVDVFKD-------------------EDHYFLLM---DQCQC-----SLTEVLLKK---------------KKLSEHEAAVVIKNVARTVGKMHDMG ...| .|. | ..|... | . |. | . . .. ....|.||. ... .. | .|... IIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN MAHRDIKTDN .|||.| .| IVHRDLKPEN |
|||||||||
Kinase | CAMK1c-S1_g.AA | Ciliate-E2-Unclassified | 56-154 | 13 | 1.1e-07 | 22.82 | In-house | 1-174 (352) | Show / Hide |
Range on Protein: 56-154 Range on HMM: 1-174/352 Sequence Identity: 13% (23 aa) FSVEKELGRGG-----HCVQSET----------VLTKLSKSKERSG------------------------------------VVQLVDVFKDEDHYFLLM . . | .|.|| .|..... . . .. . .. .| ....|.|... .. | YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM DQC-QCSLTEVLLKKKK-----------------LSEHEAA-----VVIKNVARTVGKMHDMG-MAHRDIKTDN ..| . .| . . |.|| ..| .|. .. . ..| . ||||| .| EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPEN |
|||||||||
Kinase | CAMK1c-S1_g.AA | ULK | 87-151 | 29 | 1.1e-07 | 23.36 | In-house | 77-153 (324) | Show / Hide |
Range on Protein: 87-151 Range on HMM: 77-153/324 Sequence Identity: 29% (23 aa) VVQLVDVFKDEDH--YFLLMDQCQC-SLTEVLLKKKK---------LSEHEAAVVIKNVARTVGKMHDMGMAHRDIK .|.| |.|.. .| ... |. |.. | . . |.|| ||| || ..| . .|... ||||| IVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIK |
|||||||||
Kinase | CAMK1c-S1_g.AA | Ciliate-E2 | 56-154 | 11 | 3.7e-07 | 20.61 | In-house | 1-191 (365) | Show / Hide |
Range on Protein: 56-154 Range on HMM: 1-191/365 Sequence Identity: 11% (22 aa) FSVEKELGRGGHC-----VQSET---------------------------------------VLTKLSKSKERSG------------------VVQLVDV . . | .|.|.. . .. .. ... .| ....... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FK--DEDHYFLLMDQCQC-SLTEVLLKK-----------KKLSEHEAAVVIKNVAR---------------TVGKMHDMG-MAHRDIKTDN |. |.....| |. || .| . . .. |...| |.. ..| ... . .| . ||||| .| FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPEN |
|||||||||
Kinase | CAMK1c-S1_g.AA | Ciliate-E2-Unclassified | 212-254 | 29 | 8e-06 | 16.27 | In-house | 302-352 (352) | Show / Hide |
Range on Protein: 212-254 Range on HMM: 302-352/352 Sequence Identity: 29% (15 aa) DVPLSSLDW----TDVTEEAKDLIL----QLLHLNPRKRLPIHEIEKHPWV .. .. .| .. .||||.| ..| || ||. . .| .||| NIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
|||||||||
Kinase | CAMK1c-S1_g.AA | RSK | 168-203 | 36 | 5.6e-05 | 13.97 | In-house | 167-202 (271) | Show / Hide |
Range on Protein: 168-203 Range on HMM: 167-202/271 Sequence Identity: 36% (13 aa) GTQMYSAPEMVNSDEYDEMVDVWGMGIVLYEILSGT .| | |||... .|. .|.| |...|| |.|. YTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLTGC |
|||||||||
Kinase | CAMK1c-S1_g.AA | TyrKc | 56-254 | 16 | 8.1e-05 | -144.73 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 56-254 Range on HMM: 1-280/280 Sequence Identity: 16% (46 aa) FSVEKELGRG-------GHCVQSETVLTKLSK--------------SKE--R-SGVVQLVDVFKDE-------DHYFLLMDQCQC-SLTEVLLKKKK-LS . .|.||.| |. ..| | | .| . .|.|. | .. . ....| . .| . | |... |. ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLC EHEAAVVIKNVARTVGKMHDMGMAHRDIKTDN----RGPGIK---FRMSNLAGTQ--------MYS----------------APEMVNSDEYDEMVDVWG . .|. |... |||. . | .. .| | .| . .|. ||| | .. . ||| MKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWS MGIVLYEILSGTIALCMG-----REDVPLSSLDWTD----------------VTEEAKDLILQLLHLNPRKRLPIHEIEKHPWV |....||.. | .. . . . ..| ....| | .| .| || | FGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
|||||||||
Kinase | CAMK1c-S1_g.AA | MNK | 183-202 | 45 | 0.039601 | 3.11 | In-house | 195-214 (292) | Show / Hide |
Range on Protein: 183-202 Range on HMM: 195-214/292 Sequence Identity: 45% (9 aa) YDEMVDVWGMGIVLYEILSG || |.| .|..|| .|.| YDKRCDLWSLGVILYIMLCG |