CAMK1c-S1_c

Species: S.moellendorffii
Alias: CAMK1c-S1_c
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S1_c.AA Protein None 241 None Fasta, JSON
CAMK1c-S1_c.NA RNA None 726 None Fasta, JSON
CAMK1c-S1_c.kin_dom Protein Kinase Domain None 202 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S1_c.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CAMK1c-S1_c.AA Ciliate-E2 2-203 21 1.6e-45 154.25 In-house 94-365 (365) Show / Hide
Range on Protein: 2-203
Range on HMM: 94-365/365
Sequence Identity: 21% (63 aa)

VPELVEVFK--DEDYYHLVMELCQCL-LKDVLLKK-----------KRLNEHEAVIVIKHMTK---------------AVHKMHRRG-IAHRDIKPGNIL
. ...|.|.  |.... ||||.||   |.| . ..           |...| |.  ..|. ..               |.. .| .. | |||||| |||
IIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENIL

LGFGKSFVGNVKLANFGTSLRFSKK------GSPPGIIMRGM--------------------------RYKAPEMSS--P------DCVYDERVDMWSVG
.         .|.. ||.| .....      ..  ...|                              |.|||. .  .         ||. .|.||.|
F---------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLG

IVLYEMLSGKCAFPKLASREIEKRLRCLKNLSTSPF--------------DWISMSDQAKKLILH----LLNMDSEKRLS-LRKVKKHPWV
..|||||.||  |          .  . .... ...              .| . |...| ||      .|. | |||..   ....||| 
VILYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase CAMK1c-S1_c.AA CAMK 5-203 20 2.7e-42 133.64 In-house 103-425 (425) Show / Hide
Range on Protein: 5-203
Range on HMM: 103-425/425
Sequence Identity: 20% (68 aa)

LVEVFKD-------------------EDYYHLVM---ELCQCL-----LKDVLLKK---------------KRLNEHEAVIVIKHMTKAVHKMHRRGIAH
| ||. |                   ......||   |.|.       | | . ..               .|..|.||  ... .  ||| .| ..|.|
LYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVH

RDIKPGNILL-GFGKSFV------------GNVKLANFGTSLRFSK-------------------------------KGSPPGIIMRGMRYKA-PEMSSP
||.|| ||||   ....             .|.|.. || . .| .                                |.|.        | | ||. . 
RDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPE--------YMAAPEVLNG

-------------DCVYDERVDMWSVGIVLYEMLSGKCAFPKLAS---------------REIEKRLRCLK-NLSTSPFD----------WISMSDQ---
                |.. .||||.|..|| ||.|.  .|  ..               .|. .. .  | .   ..|.          | . ||.   
KGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGY--PPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH

-----AKKLILHLLNMDSEKRLSLRKVKKHPWV
     .| || ..|. | |||...  ...|||.
FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase CAMK1c-S1_c.AA Pkinase 4-203 26 1.2e-36 130.6 Pfam 64-293 (293) Show / Hide
Range on Protein: 4-203
Range on HMM: 64-293/293
Sequence Identity: 26% (61 aa)

ELVEVFKDEDYYHLVMELCQC-----LLKDVLL--KKKRL--NEHEAVIVIKHMTKAVHKMHRRGIAHRDIKPGNILLGFGKSFV-GNVKLANFGTSLRF
.| ..| |.|....|||.|..      |.|..   .....   |.|.  ... . ...  .|..|| |||.|| |||.   .  .   ||.. || .  |
RLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQF

-SKKGSPPGIIMRGMRYKAPEMSSPDCVYDERVDMWSVGIVLYEMLSGKCAFPKL-------ASREIEKRLRCLKNLSTSPFDWIS--------------
   ..| .  .    .| |||    .  |. .|||||.|..|||||.|.  ||             |......    . .  . ||              
DY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFH

-MSDQAKKLILHLLNMDSEKRLSLRKVKKHPWV
 .|. .|..|  .|..| .||.. . ...|||.
NWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase CAMK1c-S1_c.AA Ciliate-E2-Unclassified 2-203 21 8.1e-35 118.21 In-house 83-352 (352) Show / Hide
Range on Protein: 2-203
Range on HMM: 83-352/352
Sequence Identity: 21% (60 aa)

VPELVEVFKDEDYYHLVMELC------QCLLK------------DVLLKKKRLNEHEAV-----IVIKHMTKAVHKMHRRG-IAHRDIKPGNILLGFGKS
.  ....|.|...  .|||.|      |.. |            . ....|.. | .|.       ...  ..  ..|. . | |||||| |||.  ...
IVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK

FVGNVKLANFGTSL-----------------------RFSKKGSPPGIIMRGMRYKAPEMSSPDCVYDER----VDMWSVGIVLYEMLSGKCAFP--KLA
  ...|.. || |                          .. |.|  .. .   | |||.    . ||..    .|.||.|..||||| |.. |.  .  
-NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMP-Q---YTAPEVLQ-GQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCE

S-------------REIEKRLRCLKNLSTSPFDW----ISMSDQAKKLIL----HLLNMDSEKRLSLRKVKKHPWV
.             |.. ..  . ||.. ..|.|       |..|| .|      .|. . .||... ....||| 
QHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase CAMK1c-S1_c.AA MSK 4-203 33 2.7e-32 106.46 In-house 65-277 (277) Show / Hide
Range on Protein: 4-203
Range on HMM: 65-277/277
Sequence Identity: 33% (72 aa)

ELVEVFKDEDYYHLVMELCQ-CLLKDVLLKKKRLNEHEAVIVIKHMTKAVHKMHRRGIAHRDIKPGNILLGFGKSFVGNVKLANFGTSLRFSKKGSPPGI
.| ..|.|.   .||||.|.   |   . |...  |.|. ...     ||  || .|| |||.|| |||.  ...  | |||  || .  | .  . .  
NLHYAFQDQCHTYLVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFD-DEEDNGHVKLIDFGFARLFPQDEEWRMK

IMRG-MRYKAPEMSS----PDCVYDERVDMWSVGIVLYEMLSGKCAFP------K---LASREIEKRLRCLKNLSTSPFD---WISMSDQAKKLILHLLN
  .. . | ||||      .|  ||| .|.||.|..||.||.|.  |       .    .. || || .     .. .|.   | .|| .|| ||  || 
SPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICK----GEFSFPGMAWQNMSPDAKDLIQWLLT

MDSEKRLSLRKVKKHPWV
 | .|||..    .| | 
KDPKKRLGMNDLRAHEWK

Kinase CAMK1c-S1_c.AA STE 10-203 21 3.1e-30 104.02 In-house 107-359 (359) Show / Hide
Range on Protein: 10-203
Range on HMM: 107-359/359
Sequence Identity: 21% (57 aa)

KDEDYYHLVMELCQCLLKDVLLKKK---------------RLNEHEAVIVIKHMTKA-VHKMHRRGIAHRDIKPGNILLGFGKSFVGNVKLANFGTSLRF
|..|. ...||..     | ..|.|               |..|..  ....   |.  .  |. .| ||||||.||||         |||..||.. ..
KNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------VKLCDFGVCGQL

SK-------------------K-----GSPPGIIMRGMRYKAPEMSSP-----DCVYDERVDMWSVGIVLYEMLSGKCAFPKLASREIEKRLRCLKNLS-
..                   |     |.|         . |||. ..     |  ||...|.||.|... ||. ||  . ..   .   .    .  . 
TDSMANIQSNNIIDCIETMQQKRNTFVGTP---------WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQ

----------TSP--FDWIS-----------------MSDQAKKLILHLLNMDSEKRLSLRKVKK--HPWV
          ..|   | .|                 .|.  |  | . |..| .|| .  .  |  ||..
QFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase CAMK1c-S1_c.AA CAMK-Unique 4-141 21 1.1e-24 78.29 In-house 80-290 (363) Show / Hide
Range on Protein: 4-141
Range on HMM: 80-290/363
Sequence Identity: 21% (45 aa)

ELVEV----FKDED---------------YYHLVMELCQCL-LKDVLLK--------------------KKRLNE--HEAVIVIKHMTKAVHKMHRRGIA
.|...    | |..               |...|||.||.  |.|...|                    . ...|   ..  ..   . ||  ||  .| 
KLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIV

HRDIKPGNILLGFGKSFV--------------GNVKLANFGTSLRFSKKGSP--PGIIMRGMRYKAP--------------EMSSPDCVYDERV----DM
|||.|. ||..   .||                ..||..|| .  .. . ..  . ..     |.||              |.   .| ||. .    | 
HRDLKLENIMV--CYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQC-YDQQCSPASDI

WSVGIVLYEMLSGK
|| | ..|.||.|.
WSLGVIMYYMLCGC

S_TKc CAMK1c-S1_c.AA S_TKc 1-203 24 1e-23 86.04 SMART 19-231 (231) Show / Hide
Range on Protein: 1-203
Range on HMM: 19-231/231
Sequence Identity: 24% (61 aa)

MVPE------------------------------LVEVFKDEDYYHLVMELCQC---LLKDVLLKKKR------LNEHEAVIVIKHMTKAVHKMHRRGIA
   .                              | .|| | |....|||.|      |.|.. |..|      ..| .|  ... . .|.  .|..|| 
RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGII

HRDIKPGNILLGFGKSFVGNVKLANFGTSLRFSKKGSPPGIIMRGMRYKAPEMSSPDCVYDE-RVDMWSVGIVLYEMLSGKCAFPKLASREIEKRLRCLK
|||.|| ||||        ..|.. || . ..         .     | |||.      |.  ..|.||.|..|||||.|.  ||     .. |...   
HRDLKPENILLDE------HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---

NLSTSPFDWISMSDQAKKLILHLLNMDSEKRLSLRKVKK-------HPWV
            |..|| .| ..|..| |||..  .. .       |||.
------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase CAMK1c-S1_c.AA CAMK1 5-140 32 3.9e-23 64.04 In-house 73-212 (276) Show / Hide
Range on Protein: 5-140
Range on HMM: 73-212/276
Sequence Identity: 32% (48 aa)

LVEVFKDEDYYHLVMELCQC--LLKDVLLKKKRLNEHEAVIVIKHMTKAVHKMHRRGIAHRDIKPGNILLGFGKSFVGNVK--LANFGTSLRFSKK-GSP
. |.. ......|||||..   |. |  ..|.  .| .|. ..|   .||. || .||.|||.|| |.|.  .|..   .|  .| || | .|. . .  
FYEWYESDNHFYLVMELVTGGELF-DRIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLY-YDKDEDSKIKRSIADFGLSKIFDHDEN--

PGIIMRGM----RYKAPEMSSP--DCVYDERVDMWSVGIVLYEMLSG
   .|  .     | |||.     |. ||  .||||.|...| .| |
---LMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVITYILLCG

Kinase CAMK1c-S1_c.AA RSK 109-203 34 2.7e-19 67.47 In-house 174-278 (278) Show / Hide
Range on Protein: 109-203
Range on HMM: 174-278/278
Sequence Identity: 34% (37 aa)

YKAPEMSS---PDCVYDERVDMWSVGIVLYEMLSGKCAFPK---LASREIEKRLRCLKNLSTSPFDWISMSDQAKKLILHLLNMDSEKRLS-----LRKV
| ||||     ... .|. .| || |...||||.|.  |       . || || .  | .| .   | ..|. || || ..| .| .|||.     .  .
YMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGK-FSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEI

KKHPWV
|.||| 
KQHPWF

Kinase CAMK1c-S1_c.AA ULK 4-88 29 2e-18 62.07 In-house 79-183 (324) Show / Hide
Range on Protein: 4-88
Range on HMM: 79-183/324
Sequence Identity: 29% (31 aa)

ELVEVFKDE--DYYHLVMELCQC-LLKDVLLKK---------KRLNEHEAVIVIKHMTKAVHKMHRRGIAHRDIKPGNILLGFGK---------SFVGNV
.| ..|..   ... ..||.|..  |.. . |.         |||.| ||....|.   .   .| ..| |||||| |||.  |.         .  | .
KLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVL

KLANFG
|.| ||
KIADFG

Kinase CAMK1c-S1_c.AA ULK 4-88 28 2.2e-16 53.81 In-house 82-187 (329) Show / Hide
Range on Protein: 4-88
Range on HMM: 82-187/329
Sequence Identity: 28% (31 aa)

ELVEVFKDE--DYYHLVMELCQC-LLKDVLLKK----------KRLNEHEAVIVIKHMTKAVHKMHRRGIAHRDIKPGNILLGFGK---------SFVGN
.| ..|..   ... ..||.|.   |.. . |.          |||.| ||....|.   .   .| ..| |||||| |||.  |.         .  | 
KLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGV

VKLANFG
.|.| ||
LKIADFG

Kinase CAMK1c-S1_c.AA ULK 125-203 26 5.5e-13 42.46 In-house 233-324 (324) Show / Hide
Range on Protein: 125-203
Range on HMM: 233-324/324
Sequence Identity: 26% (25 aa)

VDMWSVGIVLYEMLSGKCA----FPKLASREIEKRLRC----LKNLSTSPFDWI------SMSDQAKKLILHLLNMDSEKRLSLRKVKKHPWV
.|.||.|...|||| ||.     | ..  . |.| ..     .    . |...         |.. | ||  .|  | ..| |   . .|||.
CDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF

Kinase CAMK1c-S1_c.AA ULK 125-203 26 9.9e-13 40.85 In-house 237-329 (329) Show / Hide
Range on Protein: 125-203
Range on HMM: 237-329/329
Sequence Identity: 26% (25 aa)

VDMWSVGIVLYEMLSGKCA----FPKLASREIEKRLRCLKNLS----TSPFDWI------SMSDQAKKLILHLLNMDSEKRLSLRKVKKHPWV
.|.||.|...|||| ||.     | ..  . |.| ..  ...     . |...         |.. | ||  .|  | ..| |   . .|||.
CDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase CAMK1c-S1_c.AA CAMK1 165-203 42 3.6e-12 31.62 In-house 238-276 (276) Show / Hide
Range on Protein: 165-203
Range on HMM: 238-276/276
Sequence Identity: 42% (17 aa)

SPFDWISMSDQ-AKKLILHLLNMDSEKRLSLRKVKKHPWV
||. | . ||| || .| |.|. | .||..  .. .|||.
SPW-WDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI

Kinase CAMK1c-S1_c.AA RSK 4-72 36 1.3e-11 39.04 In-house 65-137 (278) Show / Hide
Range on Protein: 4-72
Range on HMM: 65-137/278
Sequence Identity: 36% (27 aa)

ELVEVFKDEDYYHLVMELCQ-CLLKDVLLKKKR---LNEHEAVIVIKHMTKAVHKMHRRGIAHRDIKPGNILL
.| ..|..|.. .|.||.|    | . |.|.|.   . |.|| ...   ..||  .| .|| |||.|| |||.
TLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILY

Kinase CAMK1c-S1_c.AA CAMK-Unique 169-203 23 4.7e-08 22.47 In-house 326-363 (363) Show / Hide
Range on Protein: 169-203
Range on HMM: 326-363/363
Sequence Identity: 23% (9 aa)

WIS---MSDQAKKLILHLLNMDSEKRLSLRKVKKHPWV
| .   .|..|| ..  ... |  .|.|.   ..|.|.
WHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase CAMK1c-S1_c.AA TyrKc 5-203 15 0.000289 -153.66 SMART 1-280 (280) Show / Hide
Range on Protein: 5-203
Range on HMM: 1-280/280
Sequence Identity: 15% (44 aa)

LV---------------------------------------EVFKDE------------------------DYYHLVMELCQCL-LKDVLLKKKR-LNEH
..                                       .. .                          . . .|||..    ||| | |... |.  
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

EAVIVIKHMTKAVHKMHRRGIAHRDIKPGNILLGFGKSFVGNVKLANFGTSLRFSKK---GSPPGIIM-----RGM-----RYKAPEMSSPDCVYDERVD
. .       .     |.... |||.   |.|.| ..     || . || |     .   |     ..      |      |  |||    .... .  |
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSD

MWSVGIVLYEMLS-GKCAFPK-----LASREI------EKRLRCLKN---LSTSPFDWISMSDQAKKLILHLLNMDSEKRLSLRKVKKHPWV
 || |....|... |.   |      .  .|.       .|... .|   .|   |    ..|   ....   . | |.| . . .  |   
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---F--VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF