Gene CAMK1c-S5_ae (S.moellendorffii)

CAMK1c-S5_ae

Species: S.moellendorffii
Alias: CAMK1c-S5_ae
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S5_ae.AA Protein None 306 None Fasta, JSON
CAMK1c-S5_ae.NA RNA None 921 None Fasta, JSON
CAMK1c-S5_ae.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S5_ae.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CAMK1c-S5_ae.AA S_TKc 20-270 27 4.6e-57 196.8 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-231/231
Sequence Identity: 27% (75 aa)

YTRGERLGCGRQGQVFVLKGAR---SYAGKMFRSGREAGRELRLMSKLRPCAGVVSLTGFVKERSGGACYGTMVMELCGP---SLCHRLIKGGP------
|. .. .| |  |.|.  .  .    .| |. .  . . ||.....|   .  .| | ..  .      .  ||||.|.    .| ... | |.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LGEEEAAKTIQRLAETLKEIHSRGIVHRDLKPENIFVKLDASAVHEVVIGDFGVATDDIKEMSQYCGTGKYMAPEVASCKGGHGDGSSQSLYTK-AVDVW
. | .|.. .. ... |. .||.||.|||||||||..        .. |.|||.|.      . .|||  ||||||               |.| ..|.|
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL-------------GYGKCKCDWW

ALGVIAYELLRGYK--LPQEIELLRGGVFPDGSPVSDEAEDLICGMLAVEPSERLTLDGVLE-------HPWI
..|.| ||.| ||     |. ....  .       |.|| |.|...| ..|..|.|   .|.       |||.
SCGCILYEMLCGYPPFP-QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase CAMK1c-S5_ae.AA Pkinase 20-270 25 1.6e-50 178.92 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-293/293
Sequence Identity: 25% (78 aa)

YTRGERLGCGRQGQVFVLKGARS---YAGKMFRSGREAG---------RELRLMSKLRPCAGVVSLTGFVKERSGGACYGTMVMELCGP-----SLCHRL
|..|...| |  |.|.  .   .   .| | ..  .|           .|...| .|. .  .| | ... .  .. .|  ||||.|.      .|....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFED--KDHIY--MVMEYCEGGLYVMDLFDYI

I--KGGPL--GEEEAAKTIQRLAETLKEIHSRGIVHRDLKPENIFVK--LDASAVHEVVIGDFGVA----TDDIKEMSQYCGTGKYMAPEVASCKGGHGD
   ..|..   |.|. . .  ... |. .||.||.|||||||||...   . .|   | |.|||.|    .     |. .|||  ||||||         
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-------

GSSQSLYTKAVDVWALGVIAYELLRGYKLPQEI------------ELLRGGVFPDGSPVS---------------------DEAEDLICGMLAVEPSERL
  ... |...||.|..|.| ||.| |. . ..             .. .|. ..  .| .                     .|. |.|...|.. |..|.
--GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP

TLDGVLEHPWI
| . .|.|||.
TAEQILQHPWF
Kinase CAMK1c-S5_ae.AA CAMK 89-270 23 2.2e-48 153.59 In-house 134-425 (425) Show / Hide 
Range on Protein: 89-270
Range on HMM: 134-425/425
Sequence Identity: 23% (68 aa)

MVM---ELCGP-----SLCHRLIKGGP---------------LGEEEAAKTIQRLAETLKEIHSRGIVHRDLKPENIFVKLDA-------------SAVH
|||   |.|        |  .... |.               . |.||.. .. ... .. .||..||||||||||| .  .              . ..
MVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNN

EVVIGDFGVATDDIK--------------------------EMSQYCGTGKYMA-PEVASCKGGHGDGSS-----QSLYTKAVDVWALGVIAYELLRGY-
 . | ||| |.  ..                           |. .|||  ||| ||| . ||..  . .     .  |....|.|..||| | .| || 
NIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQ-NATDEEKPYYGPKCDMWSCGVILYIMLCGYP

-----KLPQEIE-------------LLRGGVFP-DGSP---------------VSDE--------AEDLICGMLAVEPSERLTLDGVLEHPWI
     .  ...|               . | .  . ..               .|||        . |||..|| |.|..|.|.. .|.|||.
PFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CAMK1c-S5_ae.AA AGC 127-270 22 3.7e-48 121.48 In-house 169-395 (395) Show / Hide 
Range on Protein: 127-270
Range on HMM: 169-395/395
Sequence Identity: 22% (54 aa)

IHS-RGIVHRD-LKPENIFVKLDASAVHEVVIGDFGVATDDIKE-----------------------------------------------------MSQ
.|| .||.||| ||||||    |      . . ||| ..  ...                                                      . 
LHSHMGIIHRDYLKPENILLDED----GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWT

YCG--TGKYMAPEVASCKGGHGDGSSQSLYTKAVDVWA--LGVIAYELLRG-------------------YKLPQEIELLR-----GGVFP--------D
 ||  |  |||||.               |.||.| |.  ||.. ||.| |                   ... | |.  |     .  ||        .
FCGPCTPEYMAPEIL--------------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPE

GSPVSDEAEDLICGMLAVEPSERLT----------LDGVLEHPWI
 . .|.|| ||| ..| ..|..||.           . . .||| 
DRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase CAMK1c-S5_ae.AA Ciliate-E2 89-270 22 4.5e-39 131.76 In-house 111-365 (365) Show / Hide 
Range on Protein: 89-270
Range on HMM: 111-365/365
Sequence Identity: 22% (59 aa)

MVMELC-GPSLCHRLI------------KGGPLGEEEAAKTIQRLAE---------------TLKEIHSRG-IVHRDLKPENIFVKLDASAVHEVVIGDF
.|||.| | .| ....            . ... |.|... .. ...                |...||.. |.|||.|||||..         . | ||
LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDF

GVATDDIKEMSQ----------------------------------YCGTGKYMAPEVASCKGGHGDGSSQSLYTKAVDVWALGVIAYELLRGYKLPQEI
| ...  ... .                                  .|||  |||||. . |.  .. . |  |....|.|.|||| ||.| |.     .
GLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ-QKQKGYDYKCDIWSLGVILYEMLFGKPPF--Q

ELLRGGVFP------------------DGSPVSDEAEDLICG----MLAVEPSERLT-LDGVLEHPWI
.    . .                   .   .|.|. |||      || ..|..|.|  . .|.|||.
QQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CAMK1c-S5_ae.AA Ciliate-E2-Unclassified 89-270 23 5.7e-36 122.27 In-house 98-352 (352) Show / Hide 
Range on Protein: 89-270
Range on HMM: 98-352/352
Sequence Identity: 23% (61 aa)

MVMELC------------------GPSLCHRLIKGGPLGEEEAA-----KTIQRLAETLKEIHSRG-IVHRDLKPENIFVKLDASAVHEVVIGDFGVAT-
.|||.|                  |  | |.. ..  . |..|.     . .  . . |. .|. . |.|||.|||||... . .   .. | ||| .  
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-NYYIKIIDFGISKK

--DD---------------IKEMSQYCGTGKYM----APEVASCKGGHGDGSSQSLYTKAVDVWALGVIAYELLRGYKLPQE------------------
  ..                ..|.. |||  ||    ||||  .. .... ..     ...|.|.||||.||.| || .| .                  
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL-QGQNYDHSKA-----YKCDIWSLGVILYEMLFGY-YPFYDNNCEQHQQLITQWINNA

------IELLRGGVFPDGSP-------VSDEAEDLIC----GMLAVEPSERLTLDGVLEHPWI
       . . . .. . .|       .|.||.|.|      || . |..|.|.. .|.|||.
YRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CAMK1c-S5_ae.AA CAMKL 89-270 28 7.3e-34 105.33 In-house 98-297 (297) Show / Hide 
Range on Protein: 89-270
Range on HMM: 98-297/297
Sequence Identity: 28% (61 aa)

MVMELCGPS---LCHRLIKG----GPLGEEEAAKTIQRLAETLKEIHSRGIVHRDLKPENIFVKLDASAVHEVVIGDFGVA---TD--DIKE--MSQYCG
.|||.|.     | ....|     |.. |.|| .  . . . .. .||.||||||.||||| .  . .    . | ||| .   ..  ....  ..  ||
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCG

TGKYMAPEVASCKGGHGDGSS-QSLYT-KAVDVWALGVIAYELLRGYKLP--------------QEIELLRGGVFPDGSP--VSDEAEDLICGMLAVEPS
.  |||||. .         . .  |  ..||.|..||| | .. || ||               . .  ..| . .  .  || ...||| .|| | |.
SPPYMAPEIFQ---------GNNKPYDGPKVDIWSCGVILYAMVCGY-LPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPE

ERLTLDGVLEHPWI
.| |.. ...||| 
KRPTIHQIMNHPWM
Kinase CAMK1c-S5_ae.AA ULK 124-270 27 3.7e-31 106.05 In-house 143-329 (329) Show / Hide 
Range on Protein: 124-270
Range on HMM: 143-329/329
Sequence Identity: 27% (53 aa)

LKEIHSRGIVHRDLKPENIFVKLD--------ASAVHEVV--IGDFGVATD-DIK------EMSQY-----CGTGKYMAPEVASCKGGHGDGSSQSLYT-
.||.|...|.|||.||.|| .. .        . .. ..|  |.||| |   |        .|..      |||  ||||.. . .|       |  |. 
FKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV-HP-NGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQG------EQKPYYD

KAVDVWALGVIAYELLRGY------KLPQE----IELLRGG------------VFP---DGSPVSDEAEDLICGMLAVEPSERLTLDGVLEHPWI
. .|.| ||.| ||.| |.      . .|     ..|.. .             ||   .. ..|.| .||| .|| .....| . . ...|||.
YKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase CAMK1c-S5_ae.AA Ciliate-E2a 89-219 36 9.6e-31 87.74 In-house 76-213 (275) Show / Hide 
Range on Protein: 89-219
Range on HMM: 76-213/275
Sequence Identity: 36% (53 aa)

MVMELC-GPSLCHRLIKGGPLGEE--EAAKTIQRLA-ETLKEIHSRGIVHRDLKPENIFVK-LDASAV--HEVVIGDFGVATDD---IKE-MSQYCGTGK
.|||.| | .| ..... . . ||  |... .| |  . |  .|.|.|.|||||||||. | ....     ...| ||| ||.    .|. | | |||  
LVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPG

YMAPEVASCKGGHGDGS--SQSLYTKAVDVWALGVIAYELLRGY
|.||||.  |         ..  |.. .|.| .||| | || |.
YVAPEVLNNK------EVLKHKQYDTKCDMWSCGVIFYILLCGK
Kinase CAMK1c-S5_ae.AA CAMK1 110-219 39 3.7e-27 75.94 In-house 107-213 (276) Show / Hide 
Range on Protein: 110-219
Range on HMM: 107-213/276
Sequence Identity: 39% (45 aa)

EEEAAKTIQRLAETLKEIHSRGIVHRDLKPENIFVKLDASAVHEVV--IGDFGVAT---DDIKEMSQYCGTGKYMAPEVASCKGGHGDGSSQSLYTKAVD
|..|..... ... .. .||.|||||||||||.  . | .  ....  | ||| ..   .|.  |.. |||  |.||||  ||           | ||.|
EKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYY-DKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK-------DKPYDKACD

VWALGVIAYELLRGY
.|  ||| | || ||
MWSIGVITYILLCGY
Kinase CAMK1c-S5_ae.AA DCAMKL 110-219 35 6.7e-26 77.1 In-house 114-216 (279) Show / Hide 
Range on Protein: 110-219
Range on HMM: 114-216/279
Sequence Identity: 35% (41 aa)

EEEAAKTIQRLAETLKEIHSRGIVHRDLKPENIFVKLDASAVHEVVIGDFGVATDDIKE----MSQYCGTGKYMAPEVASCKGGHGDGSSQSLYTKAVDV
| .||  .  |.. || .|...|||||.||||  |. . . . ..  .||| |.  ...    ..  |||  | |||. . .|          |   ||.
ERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLAC-HVNGDFGPLYTVCGTPTYVAPEILMETG----------YGCKVDI

WALGVIAYELLRGY
||.||| | || |.
WAAGVILYILLCGF
Kinase CAMK1c-S5_ae.AA RSK 89-219 32 1e-21 76.39 In-house 78-209 (278) Show / Hide 
Range on Protein: 89-219
Range on HMM: 78-209/278
Sequence Identity: 32% (46 aa)

MVMELC-GPSLCHRLIKGGP---LGEEEAAKTIQRLAETLKEIHSRGIVHRDLKPENIFVKLDASAVHEVVIGDFGVATDDIKEMSQ----YCGTGKYMA
..||.| |. |  .| | .    . |.||.  .  .. ... .|..||.|||||||||    .     .... ||| .     ...|    .|.|  |||
LIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMA

PEVAS---CKGGHGDGSSQSLYTKAVDVWALGVIAYELLRGY
||.      .||         ..||.|.| |||. ||.| |.
PEMLKRANQQGG---------HDKACDWWSLGVLMYEMLTGC
Kinase CAMK1c-S5_ae.AA CAMK1 239-270 48 2.6e-15 40.89 In-house 244-276 (276) Show / Hide 
Range on Protein: 239-270
Range on HMM: 244-276/276
Sequence Identity: 48% (16 aa)

VSDE-AEDLICGMLAVEPSERLTLDGVLEHPWI
.||. | |.|..|| |.|..|.| . .|.||||
ISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CAMK1c-S5_ae.AA DCAMKL 239-270 46 6.9e-12 32.72 In-house 248-279 (279) Show / Hide 
Range on Protein: 239-270
Range on HMM: 248-279/279
Sequence Identity: 46% (15 aa)

VSDEAEDLICGMLAVEPSERLTLDGVLEHPWI
.|| |.|||  || |.|  | |   ...|||.
ISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CAMK1c-S5_ae.AA RSK 239-270 37 8.9e-10 32.28 In-house 242-278 (278) Show / Hide 
Range on Protein: 239-270
Range on HMM: 242-278/278
Sequence Identity: 37% (14 aa)

VSDEAEDLICGMLAVEPSERLT-----LDGVLEHPWI
.|.|| ||| .|| ..|. ||.     .. ...|||.
LSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
TyrKc CAMK1c-S5_ae.AA TyrKc 20-270 22 9.2e-10 -64.83 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-280/280
Sequence Identity: 22% (69 aa)

YTRGERLGCGRQGQVF--VLKGARSYAGKMFRSGREAG--RELRLMSKL-RPCAGVVSLTGFVKERS------GGACYGTMVMELCGP-SLCHRLIKGGP
 | |. ||.|  |.|.  ..|  .  | || ... ..   ||.|.|.||      .| | | . . .      .  .   .|||..   .| ..| | .|
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM---IVMEYMPHGDLKDYLRKHRP

-LGEEEAAKTIQRLAETLKEIHSRGIVHRDLKPENIFVKLDASAVHEVVIGDFGVATDDIKEM-------SQYCG----TGK------YMAPEVASCKGG
 |  ..  .     |.    .||....||||   |. |. .      | |.||| .  ||..        . |       ||       ||||.      
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLS-RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----

HGDGSSQSLYTKAVDVWALGVIAYELL-RGYKLPQE-----------IELLRGGVFPDGSPV---------SDEAEDLICGMLAVEPSERLTLDGVLEHP
       . .| . |||. ||  .|.. .| . . .           ||... |  ..  |          .||  ...    . .|..| |   .  | 
-----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HE

WI
 .
CF
Kinase CAMK1c-S5_ae.AA Ciliate-E2a 239-270 40 4.5e-08 19.89 In-house 244-275 (275) Show / Hide 
Range on Protein: 239-270
Range on HMM: 244-275/275
Sequence Identity: 40% (13 aa)

VSDEAEDLICGMLAVEPSERLTLDGVLEHPWI
.|.|. ||. .|| . |..|.|    |.||| 
CSKECKDLMKKMLEKDPKKRITAQQALNHPWF