Gene CAMK1c-S5_b (S.moellendorffii)

CAMK1c-S5_b

Species: S.moellendorffii
Alias: CAMK1c-S5_b
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S5_b.AA Protein None 368 None Fasta, JSON
CAMK1c-S5_b.NA RNA None 1107 None Fasta, JSON
CAMK1c-S5_b.kin_dom Protein Kinase Domain None 212 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S5_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CAMK1c-S5_b.AA S_TKc 81-329 26 1.4e-50 175.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 81-329
Range on HMM: 1-231/231
Sequence Identity: 26% (72 aa)

YMRGKRLGCGGQRQVFMIHNGH--NTYAGKLFRSGSDAEREARLMSKLHACPRVVSLKGFVRERDGAKCYGTIVMELCGP---NLCEGLINCWL------
|  .. .| |.  .|.  .. .    .| |  .   ...|| ....|   .| .| |... ..      .  .|||.|.    .| . . ..        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

MREEDAVKTIKKLAETLKAIHSRGIIHRDLKPENILVKLNATGVHDVLIGDFEIATDLHREMSKYCGTEKYMAPEVMATKGRKGESQSFYTA-AIDVWGL
. | .| . .. ... |. .||.|||||||||||||.         . |.|| .|. |    . .|||  ||||||.            |.  ..|.| .
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL-----------GYGKCKCDWWSC

GVIAYELLRGYKSRMEIDFLRARAFPTGFGSDQAEDLLRGMLAVEPSKRITLDCVLA-------HPWI
|.| ||.| ||      ...  .       |..| |..|..| ..|.||.|   .|.       |||.
GCILYEMLCGYPPFP-QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CAMK1c-S5_b.AA Pkinase 116-279 30 2.3e-35 126.1 Pfam 45-209 (293) Show / Hide 
Range on Protein: 116-279
Range on HMM: 45-209/293
Sequence Identity: 30% (55 aa)

AER--EARLMSKLHACPRVVSLKGFVRERDGAKCYGTIVMELCGP-----NLCEGLI---NCWL-MREEDAVKTIKKLAETLKAIHSRGIIHRDLKPENI
. |  |...| .|. .| .| |......  . ..|  .|||.|.       |.. .    .... . |... . .. ... |. .||.||||||||||||
HRRLSEIQIMKRLN-HPNIVRLYDWFED--KDHIY--MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENI

LVKLNATGV-HDVLIGDFEIA----TDLHREMSKYCGTEKYMAPEVMATKGRKGESQSFYTAAIDVWGLGVIAYELLRGY
|.. |   .  .| |.|| .|    .   . |. .|||  ||||||         ... |. ..|.|..|.| ||.| |.
LID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-------GGQYYGPKVDMWSCGCILYEMLCGR
Kinase CAMK1c-S5_b.AA CAMK 86-279 18 3.8e-33 103.6 In-house 1-331 (425) Show / Hide 
Range on Protein: 86-279
Range on HMM: 1-331/425
Sequence Identity: 18% (63 aa)

RLGCGGQRQVFMIHNGHNT--------------YAGKLFR---------------------------------SGSDAEREARLMSKLHA------CPRV
 || |.  .|.   . ..|              .| |                                    .    .|| ..|.||..       | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSLKGFVRERD---------GAKC-------YGTIVM---ELCGP-NLCEGLINCWL-------------------MREEDAVKTIKKLAETLKAIHSRG
..|  .   ..           ..       .  .||   |.|    |.. | .                      . |..| . .. ... .. .||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDLKPENILVKLNATGV-------------HDVLIGDFEIATDLHR--------------------------EMSKYCGTEKYMA-PEVMATKGRK-
|.||||||||||.  | ..              ... | ||  |. . .                           |. .|||  ||| |||   ||.. 
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----GESQSFYTAAIDVWGLGVIAYELLRGY
      | .  |. ..|.| .||| | .| ||
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGY
Kinase CAMK1c-S5_b.AA Ciliate-E2 151-279 25 2.1e-28 94.59 In-house 111-293 (365) Show / Hide 
Range on Protein: 151-279
Range on HMM: 111-293/365
Sequence Identity: 25% (49 aa)

IVMELC-GPNLCEGLINCWLMR-----------EEDAVKTIKKLAE---------------TLKAIHSRG-IIHRDLKPENILVKLNATGVHDVLIGDFE
.|||.| | .| . ..|... |           |. . . .|....                |. .||.. |||||.||||||.         . | || 
LVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDFG

IATDLHRE--------MSK--------------------------YCGTEKYMAPEVMATKGRKG-ESQSFYTAAIDVWGLGVIAYELLRGY
...... .        ..|                          .|||  |||||.   |.  . . |  |. ..|.| |||| ||.| |.
LSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK
Kinase CAMK1c-S5_b.AA DCAMKL 172-279 35 7.6e-27 80.09 In-house 114-216 (279) Show / Hide 
Range on Protein: 172-279
Range on HMM: 114-216/279
Sequence Identity: 35% (39 aa)

EEDAVKTIKKLAETLKAIHSRGIIHRDLKPENILVKLNATGVHDVLIGDFEIATDLHR---EMSKYCGTEKYMAPEVMATKGRKGESQSFYTAAIDVWGL
| ||.  . .|.. || .|...|.|||.|||| ||. .  |.  .  .||  |.   .    ..  |||  | |||... .|        |   .|.| .
ERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETG--------YGCKVDIWAA

GVIAYELLRGY
||| | || |.
GVILYILLCGF
Kinase CAMK1c-S5_b.AA Ciliate-E2a 151-279 37 3.9e-26 73.95 In-house 76-213 (275) Show / Hide 
Range on Protein: 151-279
Range on HMM: 76-213/275
Sequence Identity: 37% (53 aa)

IVMELC-GPNLCEGLINCWLMREE--DAVKTIKKLA-ETLKAIHSRGIIHRDLKPENILVK-LNATGV--HDVLIGDFEIATDLH-RE---MSKYCGTEK
.|||.| |  | . ...|. . ||  .. . ...|  . |  .|.|.|.|||||||||| | .....    |. | ||  ||. .  |   | . |||  
LVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPG

YMAPEVMATKGRKGE--SQSFYTAAIDVWGLGVIAYELLRGY
|.|||| . |    |  .. .|.   |.| .||| | || |.
YVAPEVLNNK----EVLKHKQYDTKCDMWSCGVIFYILLCGK
Kinase CAMK1c-S5_b.AA MSK 114-278 31 8.8e-25 80.69 In-house 45-206 (277) Show / Hide 
Range on Protein: 114-278
Range on HMM: 45-206/277
Sequence Identity: 31% (54 aa)

SDAEREARLMSKLHACPRVVSLKGFVRERDGAKCYGTIVMELC-GPNLCEGLINCWLMREEDAVKTIKKLAETLKAIHSRGIIHRDLKPENILVKLNATG
. . .|..    .  .| .|.|..  ..   .. |  .|||.| |. | . .     ..|. .   . .|   .. .|..|||||||||||||   .  .
EHTQTERQCLEMCQQHPNIVNLHYAFQDQ--CHTY--LVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDN

VHDVLIGDFEIATDLHRE----MSKYCGTEKYMAPEVMATKGRKGESQSF-YTAAIDVWGLGVIAYELLRG
 | .|| ||  |  . ..    |  .|.|  |||||. ..    |..|   | .|.|.|.|||| |..| |
GHVKLI-DFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRR----GYAQDGGYDEACDWWSLGVILYTMLTG
Kinase CAMK1c-S5_b.AA CAMK1 172-279 37 2e-24 67.84 In-house 107-213 (276) Show / Hide 
Range on Protein: 172-279
Range on HMM: 107-213/276
Sequence Identity: 37% (42 aa)

EEDAVKTIKKLAETLKAIHSRGIIHRDLKPENILVKLNATGVHDVL--IGDFEIATDLH-R--EMSKYCGTEKYMAPEVMATKGRKGESQSFYTAAIDVW
|.||....|.... .. .||.|| ||||||||.| . .  . ...   | || ... .      |.. |||  |.|||| . |        .|  |.|.|
EKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDED-SKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK-----DKPYDKACDMW

GLGVIAYELLRGY
. ||| | || ||
SIGVITYILLCGY
Kinase CAMK1c-S5_b.AA CAMK-Unique 151-279 24 1.3e-23 74.61 In-house 112-290 (363) Show / Hide 
Range on Protein: 151-279
Range on HMM: 112-290/363
Sequence Identity: 24% (44 aa)

IVMELCGPN-LCEGLIN--------------------CWLMRE--EDAVKTIKKLAETLKAIHSRGIIHRDLKPENILVKLNATG------------VHD
||||.|  . | . ..                        . |   |.   . .|.. ..  || .|.|||||.|||.|. .                ..
IVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWH

VLIGDFEIATDLH----RE-MSKYCGTEKYMAPEVMATKGRKGE-------SQSFYTAAI----DVWGLGVIAYELLRGY
. . || ......    .. |...|||. |||||.   |.  .|        .. |        | | ||||.|..| |.
IKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKN-YQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGC
Kinase CAMK1c-S5_b.AA Ciliate-E2-Unclassified 151-279 27 4e-23 77.08 In-house 98-267 (352) Show / Hide 
Range on Protein: 151-279
Range on HMM: 98-267/352
Sequence Identity: 27% (48 aa)

IVMELC-GPNLCEGLINCWL-----------------MREEDAV-----KTIKKLAETLKAIHSRG-IIHRDLKPENILVKLNATGVHDVLIGDFEIATD
||||.| | .| . . ...                    |. |.     . .. . . |. .|. . |||||.||||||.. |      . | || |.  
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-NYYIKIIDFGISKK

L------------------HREMSKYCGTEKYM----APEVMATKGRKGESQSFYTAAIDVWGLGVIAYELLRGY
.                  . .|.  |||  ||    ||||.  ..  ...      ..|.|.||||.||.| ||
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA----YKCDIWSLGVILYEMLFGY
Kinase CAMK1c-S5_b.AA CMGC 81-278 17 1.4e-22 70.2 In-house 1-331 (513) Show / Hide 
Range on Protein: 81-278
Range on HMM: 1-331/513
Sequence Identity: 17% (58 aa)

YMRGKRLGCGGQRQVFM----------------IHNGHNTYAGKLFR---SGSDAE-------------REARLMSKLH----------------ACPRV
|   |..|.|   .|.                  |.. . .| | ..      .|              || ... .|.                  . .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VSLKGFVRERDGAKC-------------YGTIVMELCGPNLCEGLINC-------WLMREEDAV----------KTIKKLA----------ETLK--AIH
|.|. ... .. ..              .  .|.|... .|.. . |.         |  .. .           .||..           . ||   .|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

SRG--IIHRDLKPENILVKLNATGV----------------HDVLIGDFEIATDLHRE------------------------MSKYCGTEKYMAPEVMAT
|..  ||||||||||||.  | . .                  . |.||  |. .| .                        .. |  |  | |||..  
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

KGRKGESQ--SFYTAAIDVWGLGVIAYELLRG
 ..  . .    || .||.|..| | .|...|
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTG
Kinase CAMK1c-S5_b.AA RSK 170-279 31 3.4e-20 70.79 In-house 101-209 (278) Show / Hide 
Range on Protein: 170-279
Range on HMM: 101-209/278
Sequence Identity: 31% (36 aa)

MREEDAVKTIKKLAETLKAIHSRGIIHRDLKPENILVKLNATGVHDVLIGDFEIATDLHRE----MSKYCGTEKYMAPEVMATKGRKGESQSFYTAAIDV
. |..|   . ... ... .|..|||||||||||||      .   . . ||  .  .. .    . ..|.|  |||||. ..    .. |. ...| |.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKR----ANQQGGHDKACDW

WGLGVIAYELLRGY
| |||. ||.| |.
WSLGVLMYEMLTGC
Kinase CAMK1c-S5_b.AA CAMK 299-329 41 5.1e-14 40.87 In-house 387-425 (425) Show / Hide 
Range on Protein: 299-329
Range on HMM: 387-425/425
Sequence Identity: 41% (16 aa)

SDQ--------AEDLLRGMLAVEPSKRITLDCVLAHPWI
||.        . ||.|.|| |.|.||.|.. .|.|||.
SDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CAMK1c-S5_b.AA CAMK1 299-329 53 2.3e-13 35.14 In-house 245-276 (276) Show / Hide 
Range on Protein: 299-329
Range on HMM: 245-276/276
Sequence Identity: 53% (17 aa)

SDQ-AEDLLRGMLAVEPSKRITLDCVLAHPWI
||| | |....|| |.|.||.| . .|.||||
SDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CAMK1c-S5_b.AA DCAMKL 299-329 48 6.1e-11 29.71 In-house 249-279 (279) Show / Hide 
Range on Protein: 299-329
Range on HMM: 249-279/279
Sequence Identity: 48% (15 aa)

SDQAEDLLRGMLAVEPSKRITLDCVLAHPWI
||.|.|| . || |.| || |   ...|||.
SDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CAMK1c-S5_b.AA Ciliate-E2 299-329 38 3.6e-10 31.11 In-house 330-365 (365) Show / Hide 
Range on Protein: 299-329
Range on HMM: 330-365/365
Sequence Identity: 38% (14 aa)

SDQAEDLLRG----MLAVEPSKRIT-LDCVLAHPWI
|... ||..     || ..|.||||  . .| |||.
SQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CAMK1c-S5_b.AA CMGC 297-329 36 1e-09 27.15 In-house 468-513 (513) Show / Hide 
Range on Protein: 297-329
Range on HMM: 468-513/513
Sequence Identity: 36% (17 aa)

FGS-------------DQAEDLLRGMLAVEPSKRITLDCVLAHPWI
|.|             .|| ||| .||  .|.|||| .  |.||..
FKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CAMK1c-S5_b.AA Ciliate-E2a 299-329 45 2e-09 23.92 In-house 245-275 (275) Show / Hide 
Range on Protein: 299-329
Range on HMM: 245-275/275
Sequence Identity: 45% (14 aa)

SDQAEDLLRGMLAVEPSKRITLDCVLAHPWI
|... ||...|| . |.||||    | ||| 
SKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase CAMK1c-S5_b.AA RSK 299-329 36 4.9e-09 29.55 In-house 243-278 (278) Show / Hide 
Range on Protein: 299-329
Range on HMM: 243-278/278
Sequence Identity: 36% (13 aa)

SDQAEDLLRGMLAVEPSKRIT-----LDCVLAHPWI
|. | ||.|.|| ..|.||..     .. ...|||.
SQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CAMK1c-S5_b.AA Ciliate-E2-Unclassified 299-329 40 5e-09 27.47 In-house 318-352 (352) Show / Hide 
Range on Protein: 299-329
Range on HMM: 318-352/352
Sequence Identity: 40% (14 aa)

SDQAEDLLR----GMLAVEPSKRITLDCVLAHPWI
|..|.|...     || . |.||||.. .| |||.
SPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CAMK1c-S5_b.AA Pkinase 299-329 35 5.6e-08 29.28 Pfam 263-293 (293) Show / Hide 
Range on Protein: 299-329
Range on HMM: 263-293/293
Sequence Identity: 35% (11 aa)

SDQAEDLLRGMLAVEPSKRITLDCVLAHPWI
|. . |.....|.. |.||.| ...| |||.
SEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CAMK1c-S5_b.AA TyrKc 81-323 21 1.1e-07 -98.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 81-323
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YMRGKRLGCGGQRQVFMIHNGHNTYAGKLFRSGSDAE---REARLMSKL-HACPRVVSLKGFVRER------DGAKCYGTIVMELCGP-NLCEGLINCWL
   || ||.|   .|.  .    . | |  ....  |   ||||.|.||    | .| | | ...       ..  .   ||||..   .| . | ..  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM---IVMEYMPHGDLKDYLRKHRP

-MREEDAVKTIKKLAETLKAIHSRGIIHRDLKPENILVKLNATGVHDVLIGDFEIATDLHRE------MSKYC-----GTE-----KYMAPEVMATKGRK
    .| ..     |.    .||...|||||   |.||. |      | |.||  . |.. .       . |      |.      . ||||..      
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI------

GESQSFYTAAIDVWGLGVIAYELL-RGYKSRME-----IDFLRARAF-PTGFGSDQAED---------------LLRGMLAVEPSKRIT----LDCV
    . .| . |||  ||  .|.. .| .   .     ..  .....  .|.  .| ..               . .   . .|..| |     .| 
--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CAMK1c-S5_b.AA CAMK-Unique 299-329 32 1.7e-07 20.63 In-house 333-363 (363) Show / Hide 
Range on Protein: 299-329
Range on HMM: 333-363/363
Sequence Identity: 32% (10 aa)

SDQAEDLLRGMLAVEPSKRITLDCVLAHPWI
|..| |.. . . |.|..|...   | |.||
SQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase CAMK1c-S5_b.AA MSK 299-329 35 1e-06 18.68 In-house 247-277 (277) Show / Hide 
Range on Protein: 299-329
Range on HMM: 247-277/277
Sequence Identity: 35% (11 aa)

SDQAEDLLRGMLAVEPSKRITLDCVLAHPWI
| .| ||....| . |.|| ...  .|| |.
SPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK