Gene CAMK1c-S5_e (S.moellendorffii)

CAMK1c-S5_e

Species: S.moellendorffii
Alias: CAMK1c-S5_e
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S5_e.AA Protein None 307 None Fasta, JSON
CAMK1c-S5_e.NA RNA None 924 None Fasta, JSON
CAMK1c-S5_e.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S5_e.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CAMK1c-S5_e.AA S_TKc 20-268 26 1.1e-56 195.49 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-268
Range on HMM: 1-231/231
Sequence Identity: 26% (72 aa)

YMRGKRLGCGGQGQVFMIHNGR--NTYAGKLFRSGSDAEREARLMSKLHACPGVVSSKGFVRERDGAKCYGTIVMELCGP---NLCEGLINCGP------
|  .. .| |. |.|.  .. .    .| |  .   ...|| ....|   .| .|  ... ..      .  .|||.|.    .| . . ..|.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

MREEDVAKTIKKLAETLKEIHSRGIIHRDLKPENILVKLNATSVHDVLIGDFGIATDLHREMSKYCGTEKYMAPEVMARKGRKGESQSFYTA-AIDVWGL
. | .... .. ... |. .||.|||||||||||||.         . |.|||.|. |    . .|||  ||||||.            |.  ..|.| .
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL-----------GYGKCKCDWWSC

GVIAYELLKGHK--SRMEIDFLRAGAFPTGFGSDQAEDLLRGMLAVEPSKRVTLDRVLA-------HPWI
|.| ||.| |    .  .   ..         |..| |..|..| ..|.|| |   .|.       |||.
GCILYEMLCGYPPFP-QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CAMK1c-S5_e.AA CAMK 25-268 19 1.2e-50 160.98 In-house 1-425 (425) Show / Hide 
Range on Protein: 25-268
Range on HMM: 1-425/425
Sequence Identity: 19% (83 aa)

RLGCGGQGQVFMIHNGRNT--------------YAGKLFR---------------------------------SGSDAEREARLMSKLHA------CPGV
 || |. |.|.   . ..|              .| |                                    .    .|| ..|.||..       | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSSKGFVRERD---------GAKC-------YGTIVM---ELCGP-NLCEGL------INC-------------GPMREEDVAKTIKKLAETLKEIHSRG
..   .   ..           ..       .  .||   |.|    |.. |        |             | . |..... .. ... .. .||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDLKPENILVKLNATSV-------------HDVLIGDFGIATDLHR--------------------------EMSKYCGTEKYMA-PEVMARKGRK-
|.||||||||||.  | ..              ... | ||| |. . .                           |. .|||  ||| |||  .||.. 
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----GESQSFYTAAIDVWGLGVIAYELLKG-----HKSRMEID--------------FLRAGAF--PTGFGSD-----------------------QAE
      | .  |. ..|.| .||| | .| |     .....||                 ..| .  |  . |.                       .. 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLLRGMLAVEPSKRVTLDRVLAHPWI
||.|.|| |.|.|| |.. .|.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase CAMK1c-S5_e.AA Pkinase 20-268 24 4.4e-43 153.42 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-268
Range on HMM: 1-293/293
Sequence Identity: 24% (76 aa)

YMRGKRLGCGGQGQVFMIHNGRNT--YAGKLFRSGSDAE---------REARLMSKLHACPGVVSSKGFVRERDGAKCYGTIVMELCGP-----NLCEGL
| .|...| |. |.|.  |.  .   .| | ..  .. .         .|...| .|. .| .|  ......  . ..|  .|||.|.       |.. .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFED--KDHIY--MVMEYCEGGLYVMDLFDYI

I--NCGPM--REEDVAKTIKKLAETLKEIHSRGIIHRDLKPENILVKLNATSV-HDVLIGDFGIA----TDLHREMSKYCGTEKYMAPEVMARKGRKGES
   . |..   |... . .. ... |. .||.|||||||||||||.. |   .  .| |.|||.|    .   . |. .|||  ||||||         .
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-------G

QSFYTAAIDVWGLGVIAYELLKG-----HK------SRMEIDFLRAGAFPTGFGS-----------------------DQAEDLLRGMLAVEPSKRVTLD
.. |. ..|.|..|.| ||.| |     ..      . |.. ... |. .    .                       . . |.....|.. |.|| | .
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

RVLAHPWI
 .| |||.
QILQHPWF
Kinase CAMK1c-S5_e.AA Ciliate-E2a 90-217 39 9.8e-31 87.72 In-house 76-212 (275) Show / Hide 
Range on Protein: 90-217
Range on HMM: 76-212/275
Sequence Identity: 39% (55 aa)

IVMELC-GPNLCEGLINCGPMREE--DVAKTIKKLA-ETLKEIHSRGIIHRDLKPENILVK-LNATSV--HDVLIGDFGIATDLH-RE---MSKYCGTEK
.|||.| |  | . ...|. . ||  .... ...|  . |  .|.|.|.|||||||||| | ....|    |. | ||| ||. .  |   | . |||  
LVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPG

YMAPEVMARKGRKGE--SQSFYTAAIDVWGLGVIAYELLKG
|.|||| . |    |  .. .|.   |.| .||| | || |
YVAPEVLNNK----EVLKHKQYDTKCDMWSCGVIFYILLCG
Kinase CAMK1c-S5_e.AA Ciliate-E2 90-217 25 1.2e-30 102.47 In-house 111-292 (365) Show / Hide 
Range on Protein: 90-217
Range on HMM: 111-292/365
Sequence Identity: 25% (49 aa)

IVMELC-GPNLCEGLINC-----------GPMREEDVAKTIKKLAE---------------TLKEIHSRG-IIHRDLKPENILVKLNATSVHDVLIGDFG
.|||.| | .| . ..|.           ... |. ... .|....                |...||.. |||||.||||||.         . | |||
LVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDFG

IATDLHRE--------MSK--------------------------YCGTEKYMAPEVMARKGRKG-ESQSFYTAAIDVWGLGVIAYELLKG
...... .        ..|                          .|||  |||||.  .|.  . . |  |. ..|.| |||| ||.| |
LSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG
Kinase CAMK1c-S5_e.AA CMGC 20-219 17 1.9e-30 96.56 In-house 1-340 (513) Show / Hide 
Range on Protein: 20-219
Range on HMM: 1-340/513
Sequence Identity: 17% (59 aa)

YMRGKRLGCGGQGQVFM----------------IHNGRNTYAGKLFR---SGSDAE-------------REARLMSKLH----------------ACPGV
|   |..|.|  |.|.                  |.. . .| | ..      .|              || ... .|.                  . .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VSSKGFVRERDGAKC-------------YGTIVMELCGPNLCEGLINCG---------PMREED------------VAKTI------KKLAETLK--EIH
|. . ... .. ..              .  .|.|... .|.. . |.          |. |              . . .      . . . ||   .|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

SRG--IIHRDLKPENILVKLNATSV----------------HDVLIGDFGIATDLHRE------------------------MSKYCGTEKYMAPEVMAR
|..  ||||||||||||.  | ...                  . |.||| |. .| .                        .. |  |  | |||.. .
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

KGRKGESQ--SFYTAAIDVWGLGVIAYELLKG-------HK
 ..  . .    || .||.|..| | .|.. |       .|
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGK
Kinase CAMK1c-S5_e.AA MSK 90-218 37 8.7e-29 94.43 In-house 78-207 (277) Show / Hide 
Range on Protein: 90-218
Range on HMM: 78-207/277
Sequence Identity: 37% (51 aa)

IVMELC-GPNLCEGLINCGPMREEDVAKTIKKLAETLKEIHSRGIIHRDLKPENILVKLNATSVHDVLIGDFGIATDLHRE----MSKYCGTEKYMAPEV
.|||.| |. | . .   . ..|. ..  . .|   .. .|..|||||||||||||   .  . | .|| ||| |  . ..    |  .|.|  |||||.
LVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLI-DFGFARLFPQDEEWRMKSPCFTLHYMAPEM

MARKGRKGESQSF-YTAAIDVWGLGVIAYELLKGH
 .|    |..|   | .|.|.|.|||| |..| |.
LRR----GYAQDGGYDEACDWWSLGVILYTMLTGQ
Kinase CAMK1c-S5_e.AA CAMK-Unique 90-217 26 5.8e-28 89.23 In-house 112-289 (363) Show / Hide 
Range on Protein: 90-217
Range on HMM: 112-289/363
Sequence Identity: 26% (47 aa)

IVMELCGPN-LCEGLIN--------------------CGPMRE--EDVAKTIKKLAETLKEIHSRGIIHRDLKPENILVKLNAT------------SVHD
||||.|  . | . ..                      |.. |   |..  . .|.. ..  || .|.|||||.|||.|. .              | ..
IVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWH

VLIGDFGIATDLH----RE-MSKYCGTEKYMAPEVMARKGRKGE-------SQSFYTAAI----DVWGLGVIAYELLKG
. . |||......    .. |...|||. |||||.  .|.  .|        .. |        | | ||||.|..| |
IKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKN-YQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCG
Kinase CAMK1c-S5_e.AA Ciliate-E2-Unclassified 90-217 27 1.3e-26 89.37 In-house 98-266 (352) Show / Hide 
Range on Protein: 90-217
Range on HMM: 98-266/352
Sequence Identity: 27% (47 aa)

IVMELC-GPNLCEGLINCGP-----------------MREEDVA-----KTIKKLAETLKEIHSRG-IIHRDLKPENILVKLNATSVHDVLIGDFGIATD
||||.| | .| . . ...                    |. ..     . .. . . |. .|. . |||||.||||||.. |      . | ||||.  
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-NYYIKIIDFGISKK

L------------------HREMSKYCGTEKYM----APEVMARKGRKGESQSFYTAAIDVWGLGVIAYELLKG
.                  . .|.  |||  ||    ||||. ...  ...      ..|.|.||||.||.| |
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA----YKCDIWSLGVILYEMLFG
Kinase CAMK1c-S5_e.AA DCAMKL 111-217 35 6.6e-26 77.13 In-house 114-215 (279) Show / Hide 
Range on Protein: 111-217
Range on HMM: 114-215/279
Sequence Identity: 35% (39 aa)

EEDVAKTIKKLAETLKEIHSRGIIHRDLKPENILVKLNATSVHDVLIGDFGIATDLHR---EMSKYCGTEKYMAPEVMARKGRKGESQSFYTAAIDVWGL
| | |  . .|.. || .|...|.|||.|||| ||. .   .  .  .||| |.   .    ..  |||  | |||... .|        |   .|.| .
ERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETG--------YGCKVDIWAA

GVIAYELLKG
||| | || |
GVILYILLCG
Kinase CAMK1c-S5_e.AA RSK 107-218 30 9.5e-24 83.89 In-house 99-209 (278) Show / Hide 
Range on Protein: 107-218
Range on HMM: 99-209/278
Sequence Identity: 30% (37 aa)

GPMREEDVAKTIKKLAETLKEIHSRGIIHRDLKPENILVKLNATSVHDVLIGDFGIATDLHRE----MSKYCGTEKYMAPEVMA----RKGRKGESQSFY
| . |....  . ... ... .|..|||||||||||||      .   . . ||| .  .. .    . ..|.|  |||||. .    ..|        .
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGG--------H

TAAIDVWGLGVIAYELLKGH
..| |.| |||. ||.| |.
DKACDWWSLGVLMYEMLTGC
Kinase CAMK1c-S5_e.AA RSK 111-218 37 6.4e-22 75.16 In-house 100-202 (271) Show / Hide 
Range on Protein: 111-218
Range on HMM: 100-202/271
Sequence Identity: 37% (42 aa)

EEDVAKTIKKLAETLKEIHSRGIIHRDLKPENILVKLNATSVHDVLIGDFGIATDLHREMSK----YCGTEKYMAPEVMARKGRKGESQSFYTAAIDVWG
|..|.     .| ..   || ||.||||||||||.     .   . | ||| |    |   .     |.|  ||||||  |.|        ...| |.| 
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQ-LRDENGMLMTFCYTANYMAPEVLKRQG--------HDQACDWWS

LGVIAYELLKGH
.||. || | |.
FGVLMYEMLTGC
Kinase CAMK1c-S5_e.AA DCAMKL 238-268 48 1.9e-11 31.32 In-house 249-279 (279) Show / Hide 
Range on Protein: 238-268
Range on HMM: 249-279/279
Sequence Identity: 48% (15 aa)

SDQAEDLLRGMLAVEPSKRVTLDRVLAHPWI
||.|.|| . || |.| || |   ...|||.
SDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CAMK1c-S5_e.AA CMGC 236-268 34 4.7e-10 28.28 In-house 468-513 (513) Show / Hide 
Range on Protein: 236-268
Range on HMM: 468-513/513
Sequence Identity: 34% (16 aa)

FGS-------------DQAEDLLRGMLAVEPSKRVTLDRVLAHPWI
|.|             .|| ||| .||  .|.|| | .  |.||..
FKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CAMK1c-S5_e.AA RSK 238-268 36 8.6e-10 32.34 In-house 243-278 (278) Show / Hide 
Range on Protein: 238-268
Range on HMM: 243-278/278
Sequence Identity: 36% (13 aa)

SDQAEDLLRGMLAVEPSKRVT-----LDRVLAHPWI
|. | ||.|.|| ..|.|| .     ......|||.
SQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CAMK1c-S5_e.AA RSK 238-268 38 1.2e-09 30.84 In-house 236-271 (271) Show / Hide 
Range on Protein: 238-268
Range on HMM: 236-271/271
Sequence Identity: 38% (14 aa)

SDQAEDLLRGMLAVEPSKRVTL-----DRVLAHPWI
|| | ||||.|| . | .|..       ... |||.
SDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase CAMK1c-S5_e.AA Ciliate-E2 238-268 36 4.7e-09 27.19 In-house 330-365 (365) Show / Hide 
Range on Protein: 238-268
Range on HMM: 330-365/365
Sequence Identity: 36% (13 aa)

SDQAEDLLRG----MLAVEPSKRVT-LDRVLAHPWI
|... ||..     || ..|.|| |  . .| |||.
SQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CAMK1c-S5_e.AA TyrKc 20-268 22 8.3e-09 -80.28 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-268
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

YMRGKRLGCGGQGQVFMIHNGRNTYAGKLFRSGSDAE---REARLMSKL-HACPGVVSSKGFVRER------DGAKCYGTIVMELCGP-NLCEGLINCGP
   || ||.|  |.|.  .    . | |  ....  |   ||||.|.||    | .|   | ...       ..  .   ||||..   .| . | ...|
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM---IVMEYMPHGDLKDYLRKHRP

-MREEDVAKTIKKLAETLKEIHSRGIIHRDLKPENILVKLNATSVHDVLIGDFGIATDLHRE------MSKYC-----GTE-----KYMAPEVMARKGRK
    .|  .     |.    .||...|||||   |.||. |      | |.||| . |.. .       . |      |.      . ||||..      
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI------

GESQSFYTAAIDVWGLGVIAYELL-KGHKSRME-----------IDFLRAGAFPTGFGSD-------QAEDLLRGML---AVEPSKRVTLDRVLAHPWI
    . .| . |||  ||  .|..  | .   .           | ....|  .    .|         ... . |.   . .|..| |   .  |  .
--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CAMK1c-S5_e.AA Ciliate-E2a 238-268 41 1.4e-08 21.4 In-house 245-275 (275) Show / Hide 
Range on Protein: 238-268
Range on HMM: 245-275/275
Sequence Identity: 41% (13 aa)

SDQAEDLLRGMLAVEPSKRVTLDRVLAHPWI
|... ||...|| . |.|| |    | ||| 
SKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase CAMK1c-S5_e.AA CAMK-Unique 238-268 32 2.2e-08 23.57 In-house 333-363 (363) Show / Hide 
Range on Protein: 238-268
Range on HMM: 333-363/363
Sequence Identity: 32% (10 aa)

SDQAEDLLRGMLAVEPSKRVTLDRVLAHPWI
|..| |.. . . |.|..|... . | |.||
SQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase CAMK1c-S5_e.AA Ciliate-E2-Unclassified 238-268 37 4.5e-08 24.11 In-house 318-352 (352) Show / Hide 
Range on Protein: 238-268
Range on HMM: 318-352/352
Sequence Identity: 37% (13 aa)

SDQAEDLLR----GMLAVEPSKRVTLDRVLAHPWI
|..|.|...     || . |.|| |.. .| |||.
SPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CAMK1c-S5_e.AA MSK 238-268 35 4.8e-07 19.84 In-house 247-277 (277) Show / Hide 
Range on Protein: 238-268
Range on HMM: 247-277/277
Sequence Identity: 35% (11 aa)

SDQAEDLLRGMLAVEPSKRVTLDRVLAHPWI
| .| ||....| . |.|| ...  .|| |.
SPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase CAMK1c-S5_e.AA MSK 24-49 38 0.089579 1.77 In-house 2-27 (277) Show / Hide 
Range on Protein: 24-49
Range on HMM: 2-27/277
Sequence Identity: 38% (10 aa)

KRLGCGGQGQVFMIHNGRNTYAGKLF
| || ||.| .| ..  ..  .|||.
KVLGTGGYGKFFICRKCVHHDTGKLY