CAMK1c-S2_e

Species: S.moellendorffii
Alias: CAMK1c-S2_e
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S2_e.AA Protein None 229 None Fasta, JSON
CAMK1c-S2_e.NA RNA None 690 None Fasta, JSON
CAMK1c-S2_e.kin_dom Protein Kinase Domain None 192 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S2_e.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase CAMK1c-S2_e.AA Pkinase 34-225 22 3.9e-32 114.7 Pfam 75-293 (293) Show / Hide
Range on Protein: 34-225
Range on HMM: 75-293/293
Sequence Identity: 22% (50 aa)

YHLVLELCNC-----SLQDRIK--YKGQL--DEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRPGKFYVP----KVSDFGMAC---WMEDLW
...|.|.|..     .| |.|.  ..| .  .|.|  ...  ... |.  |.. |||.||||.|.|..       ...    |..||| |.   .  .  
IYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNN-----GHIDACVKICDFGLAKQFDY-NNS-

NERGAETWDYMSPEAML-DRRYITASDVWGLGMLLYTCLTATCPFPNM------DVEVVFKNARKRDRSLKNLHHNSMDWDSIPS-----------LSAR
.   . | .||.||  . .. | ...|.|..| .||  |.   |||.       |  ..... .... .      .|. .....             ...
MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECK

QLIQGMTELDPGRRFALEKVLEHEWI
..| .. ..|| .|   | .|.|.|.
DFIKWCLCKDPKKRPTAEQILQHPWF

Kinase CAMK1c-S2_e.AA CAMK 34-225 17 2.9e-30 94.14 In-house 132-425 (425) Show / Hide
Range on Protein: 34-225
Range on HMM: 132-425/425
Sequence Identity: 17% (51 aa)

YHLVL---ELCNC-----SLQDRIKYKGQ---------------LDEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRP------------GK
...|.   |.|        | |.|. .|.               ..|.| ....  ..  ..  |.. |.|.|||| |.|| .  .            ..
MYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWN

FYVPKVSDFGMACWMEDLWNER-------------------------GAETWDYMS-PEAMLD-------------RRYI-TASDVWGLGMLLYTCLTAT
 .  |..|||.|. ...  |..                            |  ||. ||  .              ..|.  ..|.| .| .||..|. .
NNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGY

CPFPNMDVEVVFKNARKRDR---SLKNLHHN------SMDWDSIPSLS----------------------ARQLIQGMTELDPGRRFALEKVLEHEWI
 ||   . .  ..   .  .   ....|...      ..... .. .|                      ...||..| . || .|. .| .|.|.|.
PPFYGDCDNEICE-D-E--WIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase CAMK1c-S2_e.AA CAMKL 34-225 21 2.9e-27 83.96 In-house 96-297 (297) Show / Hide
Range on Protein: 34-225
Range on HMM: 96-297/297
Sequence Identity: 21% (45 aa)

YHLVLELCNCS---LQDRIKYKGQ----LDEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPR-PGKFYVPKVSDFGMACWMED--LWNERGAE
..||.|.|      |.|.|. .|     ..|.|  ..   .   ..  |.. |.| |.|| |.|| .        . |..|||.. ....   ....  .
IYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN----NIKIIDFGFSNMYRPCIFGPGQKLK

TW----DYMSPEAMLD--RRYI-TASDVWGLGMLLYTCLTATCPFPNMDVE--VVFKNARKRDRSLKNLHHNSMDWDSIPSLSARQLIQGMTELDPGRRF
|.     ||.||  ..  ..|.  . |.| .| .||. .. . || . ...   .. . ... .  .  ..  ..  . .| ..|.||..| . .| .|.
TFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YY--PPIWYHVS-DCRDLIRKMLQVNPEKRP

ALEKVLEHEWI
 .. ...|.| 
TIHQIMNHPWM

Kinase CAMK1c-S2_e.AA Ciliate-E2 36-225 19 6.9e-25 82.35 In-house 111-365 (365) Show / Hide
Range on Protein: 36-225
Range on HMM: 111-365/365
Sequence Identity: 19% (53 aa)

LVLELCNC-SLQDRIK------------YKGQLDEEESAKIVIALAK---------------TLKRVHDNE-IIHCDLKPANVLLKYPRPGKFYVPKVSD
||.|.|.  .|.|.||            . ....|.| ..|   ...                |.  | .  ||| |.|| |.|.          .|..|
LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----------IKIID

FGMA------------CWMEDLWNERG----------------------AETWDYMSPEAML---------DRRYITASDVWGLGMLLYTCLTATCPFPN
||..            . .  .. . .                      . |  ||.||              .| ...|.| ||..|| .|.   ||  
FGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--

MDVEVV----FKNARKRDRSLKNLHHNSMDW--DSIPSLSARQLIQG----MTELDPGRRFA-LEKVLEHEWI
..        | .. .... .. .     .|      |... .||.     | . ||  |.   |..|.|.|.
QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase CAMK1c-S2_e.AA MSK 35-225 31 3.9e-24 78.46 In-house 77-277 (277) Show / Hide
Range on Protein: 35-225
Range on HMM: 77-277/277
Sequence Identity: 31% (66 aa)

HLVLELCNCS-LQDRIKYKGQLDEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRP-GKFYVPKVSDFGMACWMEDLWNERGAE---TWDYMS
.||.|.||   |  .|. ..  ||.| . |.  |   ..  |.  ||| |||| |.|.    . |.    |..||| |.      ..|      | .||.
YLVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHV---KLIDFGFARLFPQDEEWRMKSPCFTLHYMA

PEAMLDR------RYITASDVWGLGMLLYTCLTATCPFP--NMDVE---VVFKNARKRDRSLKNLHHNSMDWDSIPSLSARQLIQGMTELDPGRRFALEK
|| ||.|       |  | |.|.|| .||| ||   ||     |..      .  .|| .  ..    .| | .. |  |. |||.. . || .|  .. 
PE-MLRRGYAQDGGYDEACDWWSLGVILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICK-GEFSFPGMAWQNM-SPDAKDLIQWLLTKDPKKRLGMND

VLEHEWI
 . |||.
LRAHEWK

Kinase CAMK1c-S2_e.AA ULK 36-225 21 8.5e-22 74.16 In-house 94-324 (324) Show / Hide
Range on Protein: 36-225
Range on HMM: 94-324/324
Sequence Identity: 21% (50 aa)

LVLELCNC-SLQDRIK---------YKGQLDEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRPGK-------FYVPKVSDFGMACW-MEDLW
...|.||.  |.. ||         .|. | |.|  .. . ..  .|  |.. |||.|.||.| |.. . |..        .| |..||| |   ...  
IIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNM

NERGA----------ETWDYMSPEAMLDR-----RYITASDVWGLGMLLYTCLTATCPFPNMDVEVVF----KNARKRDRSL-------KNLHHNSMDWD
..              |  ||.|.   ..      |   .|.| ||...| .|.  .|| ..  .  .    |  ... .         ... ... . .
EQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNG-K-EQQIYIKNQPIQFPKPP-K

SIP-SLSARQLIQGMTELDPGRRFALEKVLEHEWI
... |   ..||..| . |.  |.  | ...|.|.
DPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF

Kinase CAMK1c-S2_e.AA CAMK-Unique 34-225 19 4.4e-21 66.16 In-house 110-363 (363) Show / Hide
Range on Protein: 34-225
Range on HMM: 110-363/363
Sequence Identity: 19% (52 aa)

YHLVLELCNCS-LQDRIKY--------------------KGQLDE--EESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRPG-----------KF
...|.|.|..  |.| |                      .|.. |   ... |.  |.  ..  |.. |.| |||. |....|. .            ..
MYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSN

YVPKVSDFGMACWMEDLWNER------GAETWDYMSP-------------EAMLD-RRYITAS----DVWGLGMLLYTCLTATCPFPNMDVE--------
.  |..|||..|  .    .       |  | .||.|             ..... ..|   .    | | || ..|. |.   ||   . .        
WHIKLCDFGLCCHYNHNKMCHMMQTMCG--TPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDK

VVFKNARKRDRSLKNL-HHNSMDWDS---IPSLSARQLIQGMTELDPGRRFALEKVLEHEWI
  |....| |     . .  .  |..   | | .| .....  ..||  |  ..  |||.||
EIFECICKGD-----YCNFDWKMWHGPDYI-SQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

S_TKc CAMK1c-S2_e.AA S_TKc 1-225 20 1.5e-19 72.21 SMART 16-231 (231) Show / Hide
Range on Protein: 1-225
Range on HMM: 16-231/231
Sequence Identity: 20% (55 aa)

MAMLEVS--------------------LKGLDEQGLVHFEQLIREEPNQYGEVYHLVLELCNC---SLQDRIKYKGQ------LDEEESAKIVIALAKTL
.   ...                    ||  .   .|..   ...      . ...|.|.|.    .| |.|| .|       ..| . ....  ... |
YKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCAL

KRVHDNEIIHCDLKPANVLLKYPRPGKFYVPKVSDFGMACWMEDLWNERGAETWDYMSPEAMLDRRYIT-ASDVWGLGMLLYTCLTATCPFPNMDVEVVF
.  |.. |||.||||.|.||         . |..|||.|. .          | .||.|| .    | . ..|.| .| .|| .|.   |||  .....|
EYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMF

KNARKRDRSLKNLHHNSMDWDSIPSLSARQLIQGMTELDPGRRFALEKVLE-------HEWI
|. .                    | .|...|... . || .|    ..|.       |.|.
KKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase CAMK1c-S2_e.AA Ciliate-E2-Unclassified 36-225 19 1.7e-19 64.27 In-house 98-352 (352) Show / Hide
Range on Protein: 36-225
Range on HMM: 98-352/352
Sequence Identity: 19% (52 aa)

LVLELC-NCSLQDRIKYKGQ-----------------LDEEESA-----KIVIALAKTLKRVHDNE-IIHCDLKPANVLLKYP-RPGKFYVPKVSDFGMA
.|.|.| . .|.. || ...                 ..|....     ..   . . |.  | .  ||| |.|| |.|..   .    | .|..||| .
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK---NYYIKIIDFGIS

C-------------------WMEDLWNERGAETWDYM----SPEAMLDRRYI----TASDVWGLGMLLYTCLTATCPFPNMDVEV---------------
                    . . .|   |  |  ||    .|| .    |      ..|.|.||..|| .|. ..||.  . |                
KKYQQNNNCDTNQQQKMQIWKQQMMWTFCG--TPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRK

VFKNARKRDRSL----------KNLHHNSMDWDSIPSLSARQLIQGMTELDPGRRFALEKVLEHEWI
 ...  |               |... .  |  .       .|.| | . .|. |  .|..|.| |.
QLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIN-------DLLQKMLKKNPNKRITFEQILNHPWF

Kinase CAMK1c-S2_e.AA RSK 35-225 25 1.6e-17 60.88 In-house 77-278 (278) Show / Hide
Range on Protein: 35-225
Range on HMM: 77-278/278
Sequence Identity: 25% (54 aa)

HLVLELCN-CSLQDRIKYKGQ---LDEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRPGKFYVPKVSDFGMACWMEDLWNERGAE----TWD
.|..|.|.   | .... ...   ..|.| . .   ......  |.  ||| |||| |.|.   . .   . |..||| .. . .. ..  .     | .
YLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHI-KLTDFGFCKQF-RCDHNQWTMTFCYTIE

YMSPEAMLD----RR-YITASDVWGLGMLLYTCLTATCPFPN---MDVEVVFKNARKRDRSLKNLHHNSMDWDSIPSLSARQLIQGMTELDPGRRFA---
|| || ||     .. .  | |.| || |.|. ||   || .    . ....|. .| . ||.     .. |... |  |. ||..| . || .|     
YMAPE-MLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLT-----MPNWQYL-SQEAKDLIRKMLHRDPHKRLGCGP

--LEKVLEHEWI
  .| ...|.|.
QDAEEIKQHPWF

Kinase CAMK1c-S2_e.AA PLK-Unclassified 36-225 26 1.9e-17 61.31 In-house 76-264 (264) Show / Hide
Range on Protein: 36-225
Range on HMM: 76-264/264
Sequence Identity: 26% (53 aa)

LVLELCNC-SLQDRIKYK-------GQLDEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRPGKFYVPKVSDFGMACWMEDLWNERGAE--TW
..||.|.  .|.. ||..         | | |   ..  ... ||  |.| ||| |||..|..|     ..  | |  ||| |  .|    ..     | 
ILLEYCPNGTLMEYIKRRNFQLFEKKRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLN----DNMEV-KICDFGLATKLENDGEKKKTICGTP

DYMSPEAMLDRR--YITASDVWGLGMLLYTCLTATCPFPNMDVEVVFKNARKRDRSLKNLHHNSMDWDSIPSLSARQLIQGMTELDPGRRFALEKVLEHE
 | .||    .   .   .|.| .|  ||| |.   ||   ||.  .|. . ..        .|   ... | .|. |||    ..| .|. .   ..| 
NYIAPEILDGKHQGHSYEVDCWSFGCILYTLLIGKPPFETKDVKQTYKKIKCNQ--------YSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHP

WI
. 
FY

Kinase CAMK1c-S2_e.AA ULK 36-110 27 4.2e-12 38.63 In-house 97-189 (329) Show / Hide
Range on Protein: 36-110
Range on HMM: 97-189/329
Sequence Identity: 27% (26 aa)

LVLELCNC-SLQDRIKYKGQ----------LDEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRPGK-------FYVPKVSDFGMA
...|.||   |.. || ..           | |.|  .. . ..  .|  |.. |||.|.||.|.|.. . |..        .| |..||| |
IIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA

Kinase CAMK1c-S2_e.AA ULK 127-225 20 4.1e-11 35.12 In-house 217-329 (329) Show / Hide
Range on Protein: 127-225
Range on HMM: 217-329/329
Sequence Identity: 20% (24 aa)

YMSPEAMLDR-----RYITASDVWGLGMLLYTCLTATCPFPNMDVEVVF-----KNARKRDRSL-----KNLHHN---SMDWDSIPSLSARQLIQGMTEL
||.|.   ..      |   .|.| ||...| .|.  .|| ..  .  .     |. ......      ..|  .   .   | . |   ..||..| . 
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGN---DPQISPECKDLIRRMLQY

DPGRRFALEKVLEHEWI
|.  |.  | ...|.|.
DEKDRISWEELFNHPWF

TyrKc CAMK1c-S2_e.AA TyrKc 5-205 16 6e-06 -126.35 SMART 1-280 (280) Show / Hide
Range on Protein: 5-205
Range on HMM: 1-280/280
Sequence Identity: 16% (46 aa)

EVSLKGLDEQ--GLVHF----------------EQLIREEPN---QYG-----------------------EVYHLVLELC-NCSLQDRIKYKGQ-LDEE
 . .| | |   | |.                 .. ...| .   ..|                       | . .|.|.. . .|.|......  |  .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

ESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRPGKFYVPKVSDFGMACWMEDL-------WNERGAE---TWD-----YMSPEAMLDRRYITASD
.  .. .  |.     |.. .|| ||   |.|.. ..     . |.||||..   .|           | .|   . .      |.||.. .... |.||
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

VWGLGMLLY-TCLTATCPFPN-----MDVEVVFKNARKRDRSLKNLH-------------HNSMD--WDSIPS--LSARQLIQGM
||  | ...  .     | |.     |. . |... ....|  .  .             .. |   |.  |.   . ..... .
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase CAMK1c-S2_e.AA Pkinase_Tyr 128-152 40 0.000285 15.09 Pfam 181-205 (270) Show / Hide
Range on Protein: 128-152
Range on HMM: 181-205/270
Sequence Identity: 40% (10 aa)

MSPEAMLDRRYITASDVWGLGMLLY
|.||.. .... |.||||  | |..
MAPECINYGKFTTKSDVWSFGVLMW