Gene CAMK1c-S2_e (S.moellendorffii)
CAMK1c-S2_e
Species: S.moellendorffii
Alias: CAMK1c-S2_e
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
CAMK1c-S2_e.AA | Protein | None | 229 | None | Fasta, JSON |
CAMK1c-S2_e.NA | RNA | None | 690 | None | Fasta, JSON |
CAMK1c-S2_e.kin_dom | Protein Kinase Domain | None | 192 | None | Fasta, JSON |
Protein domains of CAMK1c-S2_e.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Pkinase | CAMK1c-S2_e.AA | Pkinase | 34-225 | 22 | 3.9e-32 | 114.7 | Pfam | 75-293 (293) | Show / Hide |
Range on Protein: 34-225 Range on HMM: 75-293/293 Sequence Identity: 22% (50 aa) YHLVLELCNC-----SLQDRIK--YKGQL--DEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRPGKFYVP----KVSDFGMAC---WMEDLW ...|.|.|.. .| |.|. ..| . .|.| ... ... |. |.. |||.||||.|.|.. ... |..||| |. . . IYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNN-----GHIDACVKICDFGLAKQFDY-NNS- NERGAETWDYMSPEAML-DRRYITASDVWGLGMLLYTCLTATCPFPNM------DVEVVFKNARKRDRSLKNLHHNSMDWDSIPS-----------LSAR . . | .||.|| . .. | ...|.|..| .|| |. |||. | ..... .... . .|. ..... ... MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECK QLIQGMTELDPGRRFALEKVLEHEWI ..| .. ..|| .| | .|.|.|. DFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | CAMK1c-S2_e.AA | CAMK | 34-225 | 17 | 2.9e-30 | 94.14 | In-house | 132-425 (425) | Show / Hide |
Range on Protein: 34-225 Range on HMM: 132-425/425 Sequence Identity: 17% (51 aa) YHLVL---ELCNC-----SLQDRIKYKGQ---------------LDEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRP------------GK ...|. |.| | |.|. .|. ..|.| .... .. .. |.. |.|.|||| |.|| . . .. MYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWN FYVPKVSDFGMACWMEDLWNER-------------------------GAETWDYMS-PEAMLD-------------RRYI-TASDVWGLGMLLYTCLTAT . |..|||.|. ... |.. | ||. || . ..|. ..|.| .| .||..|. . NNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGY CPFPNMDVEVVFKNARKRDR---SLKNLHHN------SMDWDSIPSLS----------------------ARQLIQGMTELDPGRRFALEKVLEHEWI || . . .. . . ....|... ..... .. .| ...||..| . || .|. .| .|.|.|. PPFYGDCDNEICE-D-E--WIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | CAMK1c-S2_e.AA | CAMKL | 34-225 | 21 | 2.9e-27 | 83.96 | In-house | 96-297 (297) | Show / Hide |
Range on Protein: 34-225 Range on HMM: 96-297/297 Sequence Identity: 21% (45 aa) YHLVLELCNCS---LQDRIKYKGQ----LDEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPR-PGKFYVPKVSDFGMACWMED--LWNERGAE ..||.|.| |.|.|. .| ..|.| .. . .. |.. |.| |.|| |.|| . . |..|||.. .... .... . IYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN----NIKIIDFGFSNMYRPCIFGPGQKLK TW----DYMSPEAMLD--RRYI-TASDVWGLGMLLYTCLTATCPFPNMDVE--VVFKNARKRDRSLKNLHHNSMDWDSIPSLSARQLIQGMTELDPGRRF |. ||.|| .. ..|. . |.| .| .||. .. . || . ... .. . ... . . .. .. . .| ..|.||..| . .| .|. TFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YY--PPIWYHVS-DCRDLIRKMLQVNPEKRP ALEKVLEHEWI .. ...|.| TIHQIMNHPWM |
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Kinase | CAMK1c-S2_e.AA | Ciliate-E2 | 36-225 | 19 | 6.9e-25 | 82.35 | In-house | 111-365 (365) | Show / Hide |
Range on Protein: 36-225 Range on HMM: 111-365/365 Sequence Identity: 19% (53 aa) LVLELCNC-SLQDRIK------------YKGQLDEEESAKIVIALAK---------------TLKRVHDNE-IIHCDLKPANVLLKYPRPGKFYVPKVSD ||.|.|. .|.|.|| . ....|.| ..| ... |. | . ||| |.|| |.|. .|..| LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----------IKIID FGMA------------CWMEDLWNERG----------------------AETWDYMSPEAML---------DRRYITASDVWGLGMLLYTCLTATCPFPN ||.. . . .. . . . | ||.|| .| ...|.| ||..|| .|. || FGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-- MDVEVV----FKNARKRDRSLKNLHHNSMDW--DSIPSLSARQLIQG----MTELDPGRRFA-LEKVLEHEWI .. | .. .... .. . .| |... .||. | . || |. |..|.|.|. QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | CAMK1c-S2_e.AA | MSK | 35-225 | 31 | 3.9e-24 | 78.46 | In-house | 77-277 (277) | Show / Hide |
Range on Protein: 35-225 Range on HMM: 77-277/277 Sequence Identity: 31% (66 aa) HLVLELCNCS-LQDRIKYKGQLDEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRP-GKFYVPKVSDFGMACWMEDLWNERGAE---TWDYMS .||.|.|| | .|. .. ||.| . |. | .. |. ||| |||| |.|. . |. |..||| |. ..| | .||. YLVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHV---KLIDFGFARLFPQDEEWRMKSPCFTLHYMA PEAMLDR------RYITASDVWGLGMLLYTCLTATCPFP--NMDVE---VVFKNARKRDRSLKNLHHNSMDWDSIPSLSARQLIQGMTELDPGRRFALEK || ||.| | | |.|.|| .||| || || |.. . .|| . .. .| | .. | |. |||.. . || .| .. PE-MLRRGYAQDGGYDEACDWWSLGVILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICK-GEFSFPGMAWQNM-SPDAKDLIQWLLTKDPKKRLGMND VLEHEWI . |||. LRAHEWK |
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Kinase | CAMK1c-S2_e.AA | ULK | 36-225 | 21 | 8.5e-22 | 74.16 | In-house | 94-324 (324) | Show / Hide |
Range on Protein: 36-225 Range on HMM: 94-324/324 Sequence Identity: 21% (50 aa) LVLELCNC-SLQDRIK---------YKGQLDEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRPGK-------FYVPKVSDFGMACW-MEDLW ...|.||. |.. || .|. | |.| .. . .. .| |.. |||.|.||.| |.. . |.. .| |..||| | ... IIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNM NERGA----------ETWDYMSPEAMLDR-----RYITASDVWGLGMLLYTCLTATCPFPNMDVEVVF----KNARKRDRSL-------KNLHHNSMDWD .. | ||.|. .. | .|.| ||...| .|. .|| .. . . | ... . ... ... . . EQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNG-K-EQQIYIKNQPIQFPKPP-K SIP-SLSARQLIQGMTELDPGRRFALEKVLEHEWI ... | ..||..| . |. |. | ...|.|. DPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF |
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Kinase | CAMK1c-S2_e.AA | CAMK-Unique | 34-225 | 19 | 4.4e-21 | 66.16 | In-house | 110-363 (363) | Show / Hide |
Range on Protein: 34-225 Range on HMM: 110-363/363 Sequence Identity: 19% (52 aa) YHLVLELCNCS-LQDRIKY--------------------KGQLDE--EESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRPG-----------KF ...|.|.|.. |.| | .|.. | ... |. |. .. |.. |.| |||. |....|. . .. MYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSN YVPKVSDFGMACWMEDLWNER------GAETWDYMSP-------------EAMLD-RRYITAS----DVWGLGMLLYTCLTATCPFPNMDVE-------- . |..|||..| . . | | .||.| ..... ..| . | | || ..|. |. || . . WHIKLCDFGLCCHYNHNKMCHMMQTMCG--TPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDK VVFKNARKRDRSLKNL-HHNSMDWDS---IPSLSARQLIQGMTELDPGRRFALEKVLEHEWI |....| | . . . |.. | | .| ..... ..|| | .. |||.|| EIFECICKGD-----YCNFDWKMWHGPDYI-SQEAKDFVKCCMTVDPDHRWSAKELLEHQWI |
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S_TKc | CAMK1c-S2_e.AA | S_TKc | 1-225 | 20 | 1.5e-19 | 72.21 | SMART | 16-231 (231) | Show / Hide |
Range on Protein: 1-225 Range on HMM: 16-231/231 Sequence Identity: 20% (55 aa) MAMLEVS--------------------LKGLDEQGLVHFEQLIREEPNQYGEVYHLVLELCNC---SLQDRIKYKGQ------LDEEESAKIVIALAKTL . ... || . .|.. ... . ...|.|.|. .| |.|| .| ..| . .... ... | YKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCAL KRVHDNEIIHCDLKPANVLLKYPRPGKFYVPKVSDFGMACWMEDLWNERGAETWDYMSPEAMLDRRYIT-ASDVWGLGMLLYTCLTATCPFPNMDVEVVF . |.. |||.||||.|.|| . |..|||.|. . | .||.|| . | . ..|.| .| .|| .|. ||| .....| EYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMF KNARKRDRSLKNLHHNSMDWDSIPSLSARQLIQGMTELDPGRRFALEKVLE-------HEWI |. . | .|...|... . || .| ..|. |.|. KKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | CAMK1c-S2_e.AA | Ciliate-E2-Unclassified | 36-225 | 19 | 1.7e-19 | 64.27 | In-house | 98-352 (352) | Show / Hide |
Range on Protein: 36-225 Range on HMM: 98-352/352 Sequence Identity: 19% (52 aa) LVLELC-NCSLQDRIKYKGQ-----------------LDEEESA-----KIVIALAKTLKRVHDNE-IIHCDLKPANVLLKYP-RPGKFYVPKVSDFGMA .|.|.| . .|.. || ... ..|.... .. . . |. | . ||| |.|| |.|.. . | .|..||| . IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK---NYYIKIIDFGIS C-------------------WMEDLWNERGAETWDYM----SPEAMLDRRYI----TASDVWGLGMLLYTCLTATCPFPNMDVEV--------------- . . .| | | || .|| . | ..|.|.||..|| .|. ..||. . | KKYQQNNNCDTNQQQKMQIWKQQMMWTFCG--TPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRK VFKNARKRDRSL----------KNLHHNSMDWDSIPSLSARQLIQGMTELDPGRRFALEKVLEHEWI ... | |... . | . .|.| | . .|. | .|..|.| |. QLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIN-------DLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | CAMK1c-S2_e.AA | RSK | 35-225 | 25 | 1.6e-17 | 60.88 | In-house | 77-278 (278) | Show / Hide |
Range on Protein: 35-225 Range on HMM: 77-278/278 Sequence Identity: 25% (54 aa) HLVLELCN-CSLQDRIKYKGQ---LDEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRPGKFYVPKVSDFGMACWMEDLWNERGAE----TWD .|..|.|. | .... ... ..|.| . . ...... |. ||| |||| |.|. . . . |..||| .. . .. .. . | . YLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHI-KLTDFGFCKQF-RCDHNQWTMTFCYTIE YMSPEAMLD----RR-YITASDVWGLGMLLYTCLTATCPFPN---MDVEVVFKNARKRDRSLKNLHHNSMDWDSIPSLSARQLIQGMTELDPGRRFA--- || || || .. . | |.| || |.|. || || . . ....|. .| . ||. .. |... | |. ||..| . || .| YMAPE-MLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLT-----MPNWQYL-SQEAKDLIRKMLHRDPHKRLGCGP --LEKVLEHEWI .| ...|.|. QDAEEIKQHPWF |
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Kinase | CAMK1c-S2_e.AA | PLK-Unclassified | 36-225 | 26 | 1.9e-17 | 61.31 | In-house | 76-264 (264) | Show / Hide |
Range on Protein: 36-225 Range on HMM: 76-264/264 Sequence Identity: 26% (53 aa) LVLELCNC-SLQDRIKYK-------GQLDEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRPGKFYVPKVSDFGMACWMEDLWNERGAE--TW ..||.|. .|.. ||.. | | | .. ... || |.| ||| |||..|..| .. | | ||| | .| .. | ILLEYCPNGTLMEYIKRRNFQLFEKKRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLN----DNMEV-KICDFGLATKLENDGEKKKTICGTP DYMSPEAMLDRR--YITASDVWGLGMLLYTCLTATCPFPNMDVEVVFKNARKRDRSLKNLHHNSMDWDSIPSLSARQLIQGMTELDPGRRFALEKVLEHE | .|| . . .|.| .| ||| |. || ||. .|. . .. .| ... | .|. ||| ..| .|. . ..| NYIAPEILDGKHQGHSYEVDCWSFGCILYTLLIGKPPFETKDVKQTYKKIKCNQ--------YSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHP WI . FY |
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Kinase | CAMK1c-S2_e.AA | ULK | 36-110 | 27 | 4.2e-12 | 38.63 | In-house | 97-189 (329) | Show / Hide |
Range on Protein: 36-110 Range on HMM: 97-189/329 Sequence Identity: 27% (26 aa) LVLELCNC-SLQDRIKYKGQ----------LDEEESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRPGK-------FYVPKVSDFGMA ...|.|| |.. || .. | |.| .. . .. .| |.. |||.|.||.|.|.. . |.. .| |..||| | IIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA |
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Kinase | CAMK1c-S2_e.AA | ULK | 127-225 | 20 | 4.1e-11 | 35.12 | In-house | 217-329 (329) | Show / Hide |
Range on Protein: 127-225 Range on HMM: 217-329/329 Sequence Identity: 20% (24 aa) YMSPEAMLDR-----RYITASDVWGLGMLLYTCLTATCPFPNMDVEVVF-----KNARKRDRSL-----KNLHHN---SMDWDSIPSLSARQLIQGMTEL ||.|. .. | .|.| ||...| .|. .|| .. . . |. ...... ..| . . | . | ..||..| . YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGN---DPQISPECKDLIRRMLQY DPGRRFALEKVLEHEWI |. |. | ...|.|. DEKDRISWEELFNHPWF |
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TyrKc | CAMK1c-S2_e.AA | TyrKc | 5-205 | 16 | 6e-06 | -126.35 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 5-205 Range on HMM: 1-280/280 Sequence Identity: 16% (46 aa) EVSLKGLDEQ--GLVHF----------------EQLIREEPN---QYG-----------------------EVYHLVLELC-NCSLQDRIKYKGQ-LDEE . .| | | | |. .. ...| . ..| | . .|.|.. . .|.|...... | . ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK ESAKIVIALAKTLKRVHDNEIIHCDLKPANVLLKYPRPGKFYVPKVSDFGMACWMEDL-------WNERGAE---TWD-----YMSPEAMLDRRYITASD . .. . |. |.. .|| || |.|.. .. . |.||||.. .| | .| . . |.||.. .... |.|| DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD VWGLGMLLY-TCLTATCPFPN-----MDVEVVFKNARKRDRSLKNLH-------------HNSMD--WDSIPS--LSARQLIQGM || | ... . | |. |. . |... ....| . . .. | |. |. . ..... . VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | CAMK1c-S2_e.AA | Pkinase_Tyr | 128-152 | 40 | 0.000285 | 15.09 | Pfam | 181-205 (270) | Show / Hide |
Range on Protein: 128-152 Range on HMM: 181-205/270 Sequence Identity: 40% (10 aa) MSPEAMLDRRYITASDVWGLGMLLY |.||.. .... |.|||| | |.. MAPECINYGKFTTKSDVWSFGVLMW |