Gene CAMK1c-S4_a (S.moellendorffii)

CAMK1c-S4_a

Species: S.moellendorffii
Alias: CAMK1c-S4_a
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S4_a.AA Protein None 306 None Fasta, JSON
CAMK1c-S4_a.NA RNA None 921 None Fasta, JSON
CAMK1c-S4_a.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S4_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CAMK1c-S4_a.AA S_TKc 20-269 28 3.3e-53 184.0 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-269
Range on HMM: 1-231/231
Sequence Identity: 28% (77 aa)

YIRHEKLGHGGQGQVYLLSDAARHRHRYAGKMFKSESCAERETRILDKLRPIPGVVFLHGLRRERKVGGRCFGTMVMELCGP---SLRDLAMKGP-----
|  ..|.|.|. |.||.  .     ...| |. |    ..|| .|| |    | .| |..  ..       .  ||||.|.    .|.|.  | .     
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSEEEVAEIVKELAETLKGVHSSGIVHRDLKLENVFTKLQDASTIRPVIGDFGVATDDAREMSQSCGTEKYMAPELIFVERYGLFYTK-AVDVWGLGV
  ..| ... ....... |.  || ||.||||| ||..         .  |.|||.|.      .  |||  |||||..        |.| ..|.| .|.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGC

IAYELLKGYN--RSNLEMDLLREGEFQWPANLSPEAKHLIMGMLDLDPRKRLALDQVIN-------HPWI
| ||.| ||   .   .. ...          |||||..|...|. ||.||.   .. .       |||.
ILYEMLCGYPPFP--QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase CAMK1c-S4_a.AA Pkinase 20-269 27 4.2e-44 157.04 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-269
Range on HMM: 1-293/293
Sequence Identity: 27% (83 aa)

YIRHEKLGHGGQGQVYLLSDAARHRHRYAGKMFKSESCAE---------RETRILDKLRPIPGVVFLHGLRRERKVGGRCFGTMVMELCGP-----SLRD
| ...|.| |. |.||.  .    . ..| | .| ..  .         .| .|. .|.  | .| |..  ..   ....   ||||.|.      .| |
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFED---KDHIY--MVMEYCEGGLYVMDLFD

LAM---KGPL--SEEEVAEIVKELAETLKGVHSSGIVHRDLKLENVFTK--LQDASTIRPVIGDFGVA----TDDAREMSQSCGTEKYMAPELIFVERYG
. .   .|..  ||.|.  ....... |.  || ||.|||||.||.. .   . .....  |.|||.|    .   . |.  |||  |||||.|     |
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVK--ICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GG

LFYTKAVDVWGLGVIAYELLKG----YNR------SNLEMDLLREG---EFQWPANLS-------------------PEAKHLIMGMLDLDPRKRLALDQ
  |...||.|..|.| ||.| |    ...      . ..|  .. |   .|.||   |                   .|.|..| ..|..|| ||.  .|
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQ

VINHPWI
. .|||.
ILQHPWF
Kinase CAMK1c-S4_a.AA CAMK 25-269 18 5.8e-44 139.1 In-house 1-425 (425) Show / Hide 
Range on Protein: 25-269
Range on HMM: 1-425/425
Sequence Identity: 18% (80 aa)

KLGHGGQGQVYLLSDA-A--RHR--------HRYAGKMFK---------------------------------SESCAERETRILDKLRP------IPGV
.||.|. |.|.|  .     ..|        ...| |. .                                 ..   .|| .|. ||.        | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VFLHGLRRERK---------VGGR-CFGT------MVM---ELCGPS------LRDLAMKGP---------------LSEEEVAEIVKELAETLKGVHSS
. |.     ..            .  | |      |||   |.|         .  .  .|.               ..|.|.. ... ... ..  || 
IKLYEVYEDPHYFKNTNDYET-SKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

GIVHRDLKLENVFTKLQDASTI-------------RPVIGDFGVATDDAR--------------------------EMSQSCGTEKYMA-PELIFVERY-
.|||||||.||.     . ..                 | ||| |.   .                           |. .|||  ||| ||..  ..  
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------GLFYTKAVDVWGLGVIAYELLKG----YNRSNLEMD--------------LLREGEFQWPAN------------------------LSPEA
            |....|.| .||| | .| |    |  .. |                  ..|....|                          .|.|.
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

KHLIMGMLDLDPRKRLALDQVINHPWI
|.|| .||  || ||. ..|. ||||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CAMK1c-S4_a.AA Ciliate-E2 94-269 23 1.3e-37 126.73 In-house 111-365 (365) Show / Hide 
Range on Protein: 94-269
Range on HMM: 111-365/365
Sequence Identity: 23% (63 aa)

MVMELC-GPSLRD--------------LAMKGPLSEEEVAEIVKELAE---------------TLKGVHSSG-IVHRDLKLENVFTKLQDASTIRPVIGD
.|||.| | .|.|                  ....|.|...| |....                |.  || . |.|||.|.||..          . | |
LVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIID

FGVATDDARE------MSQS----------------------------CGTEKYMAPELIFVERY-----GLFYTKAVDVWGLGVIAYELLKGYNRSNLE
|| ...   .      ..|.                            |||  ||||| .  . |     .  |....|.| |||| ||.| |.      
FGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---

MDLLREGEFQWP------------------ANLSPEAKHLIMG----MLDLDPRKRLA-LDQVINHPWI
..   ..... |                   ..|.|.|.||      ||. || ||.   .|..||||.
QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CAMK1c-S4_a.AA AGC 160-269 19 2.5e-35 87.54 In-house 196-395 (395) Show / Hide 
Range on Protein: 160-269
Range on HMM: 196-395/395
Sequence Identity: 19% (41 aa)

IGDFGVATDDARE-----------------------------------------------------MSQSCG--TEKYMAPELIFVERYGLFYTKAVDVW
. ||| ..   ..                                                      .  ||  |  ||||| .        |.||.| |
LTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL--------YGKACDWW

G--LGVIAYELLKG----YNRSN-----------LEMDLLR------EGEFQWP----------ANLSPEAKHLIMGMLDLDPRKRLA----------LD
.  ||.. ||.| |    |. ..             ... .      . . ..|           ..|||||.|| ..|  ||.|||            .
SFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAE

QVINHPWI
.. |||| 
EIKNHPWF
Kinase CAMK1c-S4_a.AA CAMK1 113-269 36 2.2e-34 97.3 In-house 106-276 (276) Show / Hide 
Range on Protein: 113-269
Range on HMM: 106-276/276
Sequence Identity: 36% (63 aa)

SEEEVAEIVKELAETLKGVHSSGIVHRDLKLENV-FTKLQDASTIRPVIGDFGVA--TDDAR-EMSQSCGTEKYMAPELIFVERYGLFYTKAVDVWGLGV
.|.. ..|.|.... ..  || |||||||| ||  .    . |.|.. | ||| .  .|.    |.. |||  |.||| .       .| ||.|.|. ||
TEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK-DKPYDKACDMWSIGV

IAYELLKGY------N-RSNLEMDLLREGEFQWPAN----LSPE-AKHLIMGMLDLDPRKRLALDQVINHPWI
| | || ||      |  ..|    . ..|. .| .     | . ||..| .||..|| ||.  .|..|||||
ITYILLCGYPPFYDENVDNELFEKIK-KCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CAMK1c-S4_a.AA RSK 110-269 31 1.1e-31 111.56 In-house 99-278 (278) Show / Hide 
Range on Protein: 110-269
Range on HMM: 99-278/278
Sequence Identity: 31% (57 aa)

GPLSEEEVAEIVKELAETLKGVHSSGIVHRDLKLENVFTKLQDASTIRPVIGDFGVATD-DAR--EMSQS-CGTEKYMAPELIFVERYGLF-YTKAVDVW
| .||.|....  |.. ...  |. ||.|||||.||.    .. .  . .. ||| .   ...  .. .. |.|  |||||.. .   .   ..||.|.|
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHDKACDWW

GLGVIAYELLKGY--------NRSNLEMDLLREGE--FQWP--ANLSPEAKHLIMGMLDLDPRKRLA-----LDQVINHPWI
 |||. ||.| |.        | ..  |.  ..|.  .  |  ..||.|||.|| .||  || |||      .... .|||.
SLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CAMK1c-S4_a.AA CAMKL 94-269 26 1.6e-31 97.76 In-house 98-297 (297) Show / Hide 
Range on Protein: 94-269
Range on HMM: 98-297/297
Sequence Identity: 26% (56 aa)

MVMELCGPS---LRDLAMKGP-----LSEEEVAEIVKELAETLKGVHSSGIVHRDLKLENVFTKLQDASTIRPVIGDFGVAT--DD-----AREMSQSCG
.|||.|.     | |   | .     ..|.|   . . . . ..  || ||||||.|.||.    .. .     | ||| ..  ..      . .. .||
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCG

TEKYMAPELIFVERYG--L-FYTKAVDVWGLGVIAYELLKGYNR-------------SNLEMDLLREGEFQWPAN--LSPEAKHLIMGMLDLDPRKRLAL
.  |||||..     |    .. ..||.| .||| | .. ||                 ...   ..| ...|    .| ....|| .||  .| ||  .
SPPYMAPEIF----QGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTI

DQVINHPWI
.|. |||| 
HQIMNHPWM
Kinase CAMK1c-S4_a.AA ULK 109-269 25 2.8e-28 95.87 In-house 114-329 (329) Show / Hide 
Range on Protein: 109-269
Range on HMM: 114-329/329
Sequence Identity: 25% (56 aa)

KGP----------LSEEEVAEIVKELAETLKGVHSSGIVHRDLKLENVFTKLQDAST--------IRPVIGDFGVATD-DAR------EMSQS-----CG
...          |||.|. .. | ... .|  |. .|.|||.|..|.  .  ...|        ..  |.||| |   |        .|...     ||
NKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCG

TEKYMAPELIFVERYGLFYT-KAVDVWGLGVIAYELLKGY-----NRSNLEM-----DLLRE----------GEFQWP-----ANLSPEAKHLIMGMLDL
|  ||||...  .  .  |. . .|.| ||.| ||.| |.     .  | .      .|..             .|.|      ..||| | || .||  
TPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQY

DPRKRLALDQVINHPWI
|...|   ....||||.
DEKDRISWEELFNHPWF
Kinase CAMK1c-S4_a.AA Ciliate-E2-Unclassified 94-217 24 6.7e-25 83.32 In-house 98-267 (352) Show / Hide 
Range on Protein: 94-217
Range on HMM: 98-267/352
Sequence Identity: 24% (42 aa)

MVMELC-GPSLRDLAMK------------------GPLSEEEVA-----EIVKELAETLKGVHSSG-IVHRDLKLENVFTKLQDASTIRPVIGDFGVAT-
.|||.| | .|..   |                    ..|....      . ... . |.  |... |.|||.|.||.. . .     .. | ||| .  
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-NYYIKIIDFGISKK

--DD---------------AREMSQSCGTEKYM----APELIFVERYG--LFYTKAVDVWGLGVIAYELLKGY
  ..                 .|.. |||  ||    |||..  . |.   .  ...|.|.||||.||.| ||
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA--YKCDIWSLGVILYEMLFGY
Kinase CAMK1c-S4_a.AA MSK 109-216 35 1.9e-24 79.52 In-house 95-206 (277) Show / Hide 
Range on Protein: 109-216
Range on HMM: 95-206/277
Sequence Identity: 35% (40 aa)

KGPLSEEEVAEIVKELAETLKGVHSSGIVHRDLKLENV-FTKLQDASTIRPVIGDFGVATDDAREMSQ---S-CGTEKYMAPELIFVERYGLF-YTKAVD
..  .|.|...|. ||   ..  |. ||.|||||.||. |.  .|  ..  .. ||| |    .....   | |.|  |||||.. .   .   | .|.|
REHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHV--KLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACD

VWGLGVIAYELLKG
.|.|||| |..| |
WWSLGVILYTMLTG
Kinase CAMK1c-S4_a.AA MAPKAPK 113-217 33 1.1e-23 69.77 In-house 101-215 (292) Show / Hide 
Range on Protein: 113-217
Range on HMM: 101-215/292
Sequence Identity: 33% (39 aa)

SEEEVAEIVKELAETLKGVHSSGIVHRDLKLENV-FTKLQDASTIRPVIGDFGVATD-------DAR----EMSQSCGTEKYMAPELIFVERYGLFYTKA
.|.|...|.|. .. ..  || .| |||||.||. .|. .. ...   ..||| |         . .    |.   |.|  ||||| . ...  ..| | 
TEREASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHNCPVK--LCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFKEAHTYDKS

VDVWGLGVIAYELLKGY
 | | |||| | .| ||
CDMWSLGVIMYIMLCGY
Kinase CAMK1c-S4_a.AA MAPKAPK 239-269 58 3e-11 30.63 In-house 262-292 (292) Show / Hide 
Range on Protein: 239-269
Range on HMM: 262-292/292
Sequence Identity: 58% (18 aa)

SPEAKHLIMGMLDLDPRKRLALDQVINHPWI
| ||| ||  .|  || .||   ||.|||||
SEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase CAMK1c-S4_a.AA Ciliate-E2-Unclassified 235-269 43 6.5e-11 34.11 In-house 314-352 (352) Show / Hide 
Range on Protein: 235-269
Range on HMM: 314-352/352
Sequence Identity: 43% (17 aa)

PANLSPEAKHLIM----GMLDLDPRKRLALDQVINHPWI
| ..|||||..|      ||. .| ||. ..|..||||.
PKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CAMK1c-S4_a.AA MSK 228-269 41 3e-10 30.82 In-house 232-277 (277) Show / Hide 
Range on Protein: 228-269
Range on HMM: 232-277/277
Sequence Identity: 41% (19 aa)

REGEFQWP----ANLSPEAKHLIMGMLDLDPRKRLALDQVINHPWI
..|||  |     | ||.||.|| ..|  || ||| ..    | |.
CKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase CAMK1c-S4_a.AA AGC 109-146 34 1.1e-08 17.04 In-house 140-186 (395) Show / Hide 
Range on Protein: 109-146
Range on HMM: 140-186/395
Sequence Identity: 34% (16 aa)

KGPLSEEEVAEIVKE-------LAETLKGVHS-SGIVHRD-LKLENV
.| ..||..  .  |       ..  |   ||  ||.||| ||.||.
EGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENI
Kinase CAMK1c-S4_a.AA TyrKc 20-269 23 1.3e-07 -99.46 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-269
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

YIRHEKLGHGGQGQVYL--LSDAARHRHRYAGKMFKSESCAE--RETRILDKL-RPIPGVVFLHGLRRER-----KVGGRCFGTMVMELCGP-SLRDLAM
    .|||.|  |.||.  ..         | || |... ..  || ||. ||    | .| |.|  ..       ..  .   .|||..   .|.|   
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM---IVMEYMPHGDLKDYLR

KGP--LSEEEVAEIVKELAETLKGVHSSGIVHRDLKLENVFTKLQDASTIRPVIGDFGVATDDARE-------MSQSC----GTE-----KYMAPELIFV
|    |. ..  ..    |.     || ...||||   |.  . .   |..  |.||| . |   .          .     |.      . |||| |  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVK--ISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--

ERYGLFYTKAVDVWGLGVIAYELLKG-----YN-----RSNLE-MDLLREGEFQWPANL--------SPEAKHLIMGM-LDLDPRKRLALDQVINHPWI
 .|| | ||  |||  ||  .|..       ..      || | . ....|.   .            |.. . || .  . || .|    ..  |  .
-NYGKFTTK-SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CAMK1c-S4_a.AA Ciliate-E2 20-39 35 0.000378 10.12 In-house 1-20 (365) Show / Hide 
Range on Protein: 20-39
Range on HMM: 1-20/365
Sequence Identity: 35% (7 aa)

YIRHEKLGHGGQGQVYLLSD
|. ..|.| |..|.||. ..
YKFIKKIGQGNFGSVYKCKV
Kinase CAMK1c-S4_a.AA Ciliate-E2-Unclassified 20-39 35 0.000562 9.71 In-house 1-20 (352) Show / Hide 
Range on Protein: 20-39
Range on HMM: 1-20/352
Sequence Identity: 35% (7 aa)

YIRHEKLGHGGQGQVYLLSD
|. ....|.||.|.||.. .
YKIIKQIGQGGFGKVYKCQH
Kinase CAMK1c-S4_a.AA ULK 20-35 43 0.003641 7.0 In-house 1-16 (329) Show / Hide 
Range on Protein: 20-35
Range on HMM: 1-16/329
Sequence Identity: 43% (7 aa)

YIRHEKLGHGGQGQVY
|. ...||.|  |.||
YCLNHCLGKGSFGKVY
Kinase CAMK1c-S4_a.AA CAMKL 20-36 41 0.101824 1.09 In-house 1-17 (297) Show / Hide 
Range on Protein: 20-36
Range on HMM: 1-17/297
Sequence Identity: 41% (7 aa)

YIRHEKLGHGGQGQVYL
|.  . ||.|. |.| |
YRIGKTLGKGSFGKVKL
Kinase CAMK1c-S4_a.AA RSK 23-36 50 0.33488 0.6 In-house 1-14 (278) Show / Hide 
Range on Protein: 23-36
Range on HMM: 1-14/278
Sequence Identity: 50% (7 aa)

HEKLGHGGQGQVYL
.. || ||.| |.|
LKVLGQGGYGKVFL