Gene TAF1-2 (S.moellendorffii)

TAF1-2

Species: S.moellendorffii
Alias: TAF1-2
External Links:
Annotation:

Classification

Group: Atypical
Family: TAF1

Sequence

Name Sequence Type Origin Length Description Download
TAF1-2.AA Protein None 1934 None Fasta, JSON
TAF1-2.NA RNA None 5802 None Fasta, JSON

Protein domain

Protein domains of TAF1-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
TBP-binding TAF1-2.AA TBP-binding 45-114 33 6.6e-15 53.29 Pfam 1-77 (77) Show / Hide 
Range on Protein: 45-114
Range on HMM: 1-77/77
Sequence Identity: 33% (26 aa)

EEEEEEEEEESSGRML-GFMFGNVDDTGDLDVE-Y----LDQEAKEHLFALAD-QLGPSLVDLELSSKARQFTASAA
   ....|..| |  | ||.|||.|  |.|. . .    ||.|.|||| .|..  || .| ...| .|. . .   |
SDDDNDNERNSRGFNLTGFLFGNIDEHGQLEDDDFREQGLDEECKEHLSSLSKMGLGSMLHEVNLLAKSERTDSDDA
DUF3591 TAF1-2.AA DUF3591 584-644 43 1e-12 47.12 Pfam 1-61 (494) Show / Hide 
Range on Protein: 584-644
Range on HMM: 1-61/494
Sequence Identity: 43% (28 aa)

FNI--SNDKYYVVKKTPQQQKLQAKKRAIVGGVKVAHSVPALRLQTM--KPKLTNKDLANFHRPK
|||  |||.||  .| . |.|     |.  |.. . || ||||||    | ||. ... .||||.
FNIIFSNDEYYDMLKENHQNKV----RQTIGNLNIEHSMPALRLQWPYYKVKLNKREARSFHRPH
UBQ TAF1-2.AA UBQ 668-741 28 4.2e-11 44.12 SMART 1-72 (72) Show / Hide 
Range on Protein: 668-741
Range on HMM: 1-72/72
Sequence Identity: 28% (22 aa)

MKVILKTLGG-KGSRLHIDASD-TLETFKMKASKKFGDLKPSENTKLMYSGRELESNKSFAEQRVPPNSVLHLVRT
|.. .|...| |   . .. || |....| .  .| |   | |  .|.|.|. || . . |.  . |.|..||. .
MQIFVKWQNGWKTFTFEVKPSDWTVSELKQHIEDKEGI--PPEQQRLIYQGK-LEDD-TLADYNIQPGSTIHLMVR
Ubiquitin TAF1-2.AA ubiquitin 673-743 29 2.2e-08 33.97 Pfam 1-73 (73) Show / Hide 
Range on Protein: 673-743
Range on HMM: 1-73/73
Sequence Identity: 29% (22 aa)

KTLGGK--GSRLHIDASDTLETFKMKASKKFGDLKPSENTKLMYSGREL-ESNKSFAEQRVPPNS-VLHLVRTKV
|||.||     . .| .|| |..|.| ..|.|   | .. .|.|.|..| | ... ..  . ..| ..|.|.   
KTLDGKGSTFTFEVDPDDTVEQLKQKIQQKQG--IPPDQQRLIYKGKQLREDHRTLSDYNIQDGSFTIHMVLRQR
DUF3591 TAF1-2.AA DUF3591 748-1157 32 4.5e-95 326.96 Pfam 85-494 (494) Show / Hide 
Range on Protein: 748-1157
Range on HMM: 85-494/494
Sequence Identity: 32% (143 aa)

KAQRLPGENKPTRPPGAFK--KKSELSVKD-GHVALMEYCEERPLLLSNVGMGAVLSTYYRKMSPTDSTAATLKEERGSWIGAVLPLEPAEDSPF--LGN
|... ..| .  ..   ||  . ..|...| ..| ||||||| |...||.|||  . .||||.. .|..  .|..     ||    | |   |||  .|.
KHDKREKERMGKDISEVFKMRTTKDLTLGDNSPVILMEYCEEYPPVMSNFGMGSKIINYYRKKHMEDTHRPKLDD-----IGETHVLHPQDKSPFWNFGH

IRLGETQSCLETNMYRAPVFQHRVSSTDFLLVRSSK-GKLS----LRRIDGLHVVGQQEPHIEVIAPSSKTVLHYLGNRLLVHVYREFR-AKDKPGMSPQ
.  ||.. .|. ||||||.|.| ...||||..||.  |. .    || || . .|||..| .|| .| |. |     ||| . ||| |.  |....    
VHPGEIVPTLYNNMYRAPIFKHKPEPTDFLCIRSTTPGGHGQKYYLRNIDHMFCVGQTFPVMEVPGPHSRKVTNMSKNRLKMIVYRLFWGQKSPRHR---

IGADELMAHF-PSLTDGFIRKRLKHCADLQRGP-HG-DMRWVMRQGYRIPSE-EELRRMVTPENVCSYESMQAGQHHLKRMGVNKLTH----------QN
|  .....|| |  ... .|.||| ... ||    .    |... |...|.| ||.| |.|||..|.|||||.||.||.. |.|..             .
ISIHDITKHFFPDQNEMQNRQRLKEFMKYQRDGGMDNQGWWKLKEGETLPDEFEEIRKMITPEDCCLYESMQVGQQHLEDAGYNNTDEFKRDYQQIQEDD

GLAAAICQIPDVPVTLATAAHIERELLITPWNLTANFVAAMMQGRNGIER--LEIIGPGDPTGRGLGFSYIRV-ALRPP--NTGAMVEKKAAAARGGGAV
. ..              .. |. |.  .|||.| ||. |. .      .  |.. |.|||||.|.|||.||.   ..   ..|  ...|..      ||
DEETKK-----------VQMKIDLEQMMAPWNTTRNFINATQG------KAMLQLHGEGDPTGCGEGFSFIRTKSMKGGFLKQGEGPQDKPKK-----AV

TGTDADLRRLSMEAAREVLLKFGVPQEEIDKLTRWDRIAM
.||.|..|....  ... . ..||| |||... .|.... 
AGTRAKERGGHSYNVAQQQRLYGVPEEEIRRIWYWQKRSL
DUF3591 TAF1-2.AA DUF3591 1201-1210 50 4.7486 0.78 Pfam 485-494 (494) Show / Hide 
Range on Protein: 1201-1210
Range on HMM: 485-494/494
Sequence Identity: 50% (5 aa)

EIWDRQVQSL
.||..|..||
RIWYWQKRSL
Bromodomain TAF1-2.AA Bromodomain 1790-1874 28 6.6e-24 80.28 Pfam 1-89 (89) Show / Hide 
Range on Protein: 1790-1874
Range on HMM: 1-89/89
Sequence Identity: 28% (26 aa)

LEEIVQ--GLKEKEFSRLFRKPV--TKKDAPDYHLVISTPMDLSTMRDRARNLFYK-CREDFLADMHQIVDNAHTYNEKRNPGIPPLADQ
...|.    ..|.... .|..||   ..  |||. .|..||||||.. ...|  |.   ..|..||...  |..|||. ... |  .|..
CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNG-PDSPIYKDARK
BROMO TAF1-2.AA BROMO 1779-1888 23 8.5e-23 82.97 SMART 1-118 (118) Show / Hide 
Range on Protein: 1779-1888
Range on HMM: 1-118/118
Sequence Identity: 23% (28 aa)

RGGGEVELANILEEIVQGLKEK--------EFSRLFRKPVTKKD--APDYHLVISTPMDLSTMRDRARNLFYKCREDFLADMHQIVDNAHTYNEKRNPGI
.     .. ..|.|..  ....        ...  |..||..|.  .|||. .| .||||.|.. . .|  |. .|.|..|. ....|. |||| ..  .
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNE-PDSEV

PPLADQLLEKCEDLLELRHS
   | .| ...|....    
YKMAKKLQKFFEEKWREFPP