RIO1-2

Species: S.moellendorffii
Alias: RIO1-2
External Links:
Annotation:

Classification

Group: Atypical
Family: RIO
Subfamily: RIO1

Sequence

Name Sequence Type Origin Length Description Download
RIO1-2.AA Protein None 471 None Fasta, JSON
RIO1-2.NA RNA None 1416 None Fasta, JSON

Protein domain

Protein domains of RIO1-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RIO1-2.AA RIO1 96-286 58 1.5e-127 430.05 In-house 33-225 (225) Show / Hide
Range on Protein: 96-286
Range on HMM: 33-225/225
Sequence Identity: 58% (114 aa)

ANVYHATTESGE--ELAVKVYKTSILVFKDRDKYVQGDFRFRHGYSKHNPRKMVKTWAEKEMRNLLRLKASGIRAPSPLVLRLHVLVMDFIGKSDGWAAP
.||||| .  |.  | |.|.|||||||||||.||| | ||||||..|||||||.|.||||||||| |.  | | .| |.... .||.|.|||| || |||
TNVYHASETNGKRAEYAIKIYKTSILVFKDREKYVDGEFRFRHGHCKHNPRKMIKIWAEKEMRNLKRIYQSEIPCPEPIMVKSNVLMMEFIGK-DGMAAP

RLKDAALSDTKYR-ESYLEIVQIMRTMYQRCRLVHGDLSEYNVLYHEGHLYIIDVSQSVDLDHPRALDFLRQDCVHVNDFFKKGGVAVMTVREL
||||. ... . . . |. ..| ||.||| |||||.||||||.|||.. ||.|||||||  ||| .|.|||.||. ||..|.| .|....||..
RLKDYQYKERDQYFHYYHQMIQYMRRMYQDCRLVHADLSEYNMLYHNDKLYMIDVSQSVEHDHPHSLEFLRMDCKNVNMYFMKHNVIIFPVRDI

Kinase RIO1-2.AA RIO1 97-286 51 7.79999999999e-123 383.54 Pfam 1-200 (200) Show / Hide
Range on Protein: 97-286
Range on HMM: 1-200/200
Sequence Identity: 51% (103 aa)

NVYHATT-ESGE-ELAVKVYKTSILVFKDRDKYVQGDFRFRHGYSKHNPRKMVKTWAEKEMRNLLRLKASGIRAPSPLVLRLHVLVMDFIGKSDGWAAPR
|||||.. |.|. |.|||.|.|....||....|...||||||.|..||.|.||..|||||.||| |... |...| |  .. |||||.|||  |||.|||
NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR

LKDAA----LSDTKYRESYLEIVQ-IMRTMYQRCRLVHGDLSEYNVLYHEG-HLYIIDVSQSVDLDHPRALDFLRQDCVHVNDFFKKGGVA--VMTVREL
|||.     ||. . .| | ||.. .|| |||.|.||||||||||.|.|.. ...|||..|.|..|||.||.||. || ....||.. ||.  ||..||.
LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDERVMDFREI





Kinase RIO1-2.AA RIO 96-300 35 3.4e-105 355.77 In-house 35-276 (276) Show / Hide
Range on Protein: 96-300
Range on HMM: 35-276/276
Sequence Identity: 35% (87 aa)

ANVYHATTESGE-----------ELAVKVYKTSILVFKDRDKYVQGDFRFRHGYSKHNPRKMVKTWAEKEMRNLLRLKASGIRAPSPLVLRLHVLVMDFI
...||. .|.||           | | |...|....||||.||. |.|.|.|...|||.|.|...||||||||. ||  ||. .| |. .. ||||| ||
SDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLWAEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFI

GKSDGWAAPRLKDAALSDTKYR-ESYLEIVQIMRTMYQRCRLVHGDLSEYNVLYHEGHL-------YIIDVSQSVDLDHPRALDFLRQDCVHVNDFFKKG
.. |. .||..... ..  . . . |.. .. ||..|| |||||.|..|.| ..|.| .       |.||..|.|  ||| ||...| ||. ||.||.|.
NH-DQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFYMIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKR

GV-AVMTVRELFDFI------------------VDPSINDDQV
.| .....||.|||                    ....  .  
FVYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM

RIO RIO1-2.AA RIO 71-292 42 1.3e-97 331.47 SMART 1-253 (253) Show / Hide
Range on Protein: 71-292
Range on HMM: 1-253/253
Sequence Identity: 42% (109 aa)

EKSDRATVEQV----KKKIIFNLL----LFHLQ----------ANVYHATT----ESGEELAVKVYKTSILVFKDRDKYVQGDFRFRHGYSKHNPRKMVK
.| |.||.|.|     ..... ..    .  .           ||||||..    ..|.| |||.|.||...||....|.||||||.|||...|.||||.
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR

TWAEKEMRNLLRLKASGIRAPSPLVLRLHVLVMDFIGKSDGWAAPRLKDAALSDTKYR---ESYLEIVQIMRTMYQRCRLVHGDLSEYNVLYH------E
 |||||.||| |....|...| |  .| |||||.|||. |||.||||||. . . .     | |  |.  || ||..|.|||.||||||.|||      .
LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGD-DGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDEND

GHLYIIDVSQSVDLDHPRALDFLRQDCVHVNDFFKKGGVAVMT-VRELFDFIVD
. ..|||.||||..|||..|.||. |.  ...||.. || .   .||.|..|..
CKVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG

Kinase RIO1-2.AA RIO3 110-301 47 5.8e-62 207.54 In-house 63-254 (254) Show / Hide
Range on Protein: 110-301
Range on HMM: 63-254/254
Sequence Identity: 47% (92 aa)

AVKVYKTSILVFKDRDKYVQGDFRFRHGYSKHNPRKMVKTWAEKEMRNLLRLKASGIRAPSPLVLRLHVLVMDFIGKSDGWAAPRLKDAALSDTKYRESY
|.||.||..  ||.||||.. ||||.  .|| ||||. . |||||| || |.. .||  |. ..|. |.||| |||. |   ||.||.  |   . .|.|
AIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIHRMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGH-DQVPAPKLKEVKLNSEEMKEAY

LEIVQIMRTMYQRCRLVHGDLSEYNVLYHEGHLYIIDVSQSVDLDHPRALDFLRQDCVHVNDFFKKGGV-AVMTVRELFDFIVDPSINDDQVE
 . . .|| .|  | ||| ||||||.|.| |....|||||||.  ||  |.|| .||  | .||.||||   .. ||||. .    |  |.  
YQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSGLNITADNEA