Gene HisK_p (S.moellendorffii)
HisK_p
Species: S.moellendorffii
Alias: HisK_p
External Links:
Annotation:
Sequence
Protein domains of HisK_p.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
---|---|---|---|---|---|---|---|---|---|
GAF | HisK_p.AA | GAF | 158-317 | 16 | 2.1e-10 | 38.83 | Pfam | 1-160 (160) | Show / Hide |
Range on Protein: 158-317 Range on HMM: 1-160/160 Sequence Identity: 16% (30 aa) VKHTILNTTLVELGKTLGLEECCL--WMPNRSGTELELFRSLRSPNA--VATSVPVHHPDIKLVFGANRAVVIPSSSPVAIHVLTAAGNASARSSC---- ..|| |.. ||...||.. |.. ... ..|.||.. .. .. | .| .. . || ...| ..|. . . . . ... DLEEILQTIMQELRQLLGCDRCMIYFFLWDEDGWELYWVAHWGWSDQPQQAR-LPM-GGIWGEVFCTCNPIV---VPDVC-DPRFR-WPCVDEDRPEHHH ---------RYAPGEVLAVRVPFLHLN---DFRVGDWSQAHGHRPFALMVLVLPPNSA-RRWRPHELD--MVDAVADQVAVAM .. . .|.| . .. . . . ||.. . . |.| .|.|. .. ..|||.|.|. CHCHYMRHMHHGIRSCLCVPIFDIIGQPGQQ---------------VWGVLCCHHC-PPRHWTEHDLECFLLQMFADQIAIAI |
|||||||||
GAF | HisK_p.AA | GAF | 158-327 | 14 | 8.6e-05 | 13.3 | SMART | 1-142 (142) | Show / Hide |
Range on Protein: 158-327 Range on HMM: 1-142/142 Sequence Identity: 14% (26 aa) VKHTILNTTLVELGKTLGLEECCLWMPNR-----SGTELELFRSLRSPNAVATSVPVHHPDIKLVFGANRAVVIPSSSPVAIHVLTAAGNASARSSCRYA ..|..|.. |....|... | ... .. ......... . |. . .. |. .| |.|| ... . . .. || DLEEICQTIVEEVHQFLQMDRCMIYLFDERQNDHGQLWCHASD---------HFPPD--GICGWVWRTGRPVNIPDVHHDP------HFFCWKDWL-RYQ PGEVLAVRVPFLHLNDFRVGDWSQAHGHRPFALMVLVLPPN-SARRWRPHELDMVDAVADQVAVAMSHASILEDSI .. |.| . ..||.. ..|.| ..... . ..|.|||.| ..| ..| . IRSFLCVPIMND----------------DGQVWGVLCAHHCHQPRHWTEEDEEFLQMIANQVAIAIQQAQLYEQLQ |
|||||||||
HisKA | HisK_p.AA | HisKA | 353-418 | 33 | 3.5e-15 | 55.89 | Pfam | 1-69 (69) | Show / Hide |
Range on Protein: 353-418 Range on HMM: 1-69/69 Sequence Identity: 33% (23 aa) ARNNFMAVMNQEMRTPMNSIIDLTHRLEE-TNMTQDQ--RALVDTILRNSTLLAKLVNSVLDLSRLEDD |.. |.| | |.|||...|. ... |.. |... .| | ...||.| . . .|.| .||.||.| AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG |
|||||||||
HisKA | HisK_p.AA | HisKA | 353-418 | 26 | 4.2e-15 | 57.42 | SMART | 1-89 (89) | Show / Hide |
Range on Protein: 353-418 Range on HMM: 1-89/89 Sequence Identity: 26% (24 aa) ARNNFMAVMNQEMRTPMNSIIDLTHRLEE----------TNMTQDQ-------------RALVDTILRNSTLLAKLVNSVLDLSRLEDD |...|.| | |.|||...|. ... |.. |... .| | ...||.| . . .|.| .|||||.| AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG |
|||||||||
HATPase_c | HisK_p.AA | HATPase_c | 465-585 | 30 | 1.9e-22 | 80.37 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 465-585 Range on HMM: 1-120/120 Sequence Identity: 30% (40 aa) GDDRRLVQVLLQITGNAVKFTKE-GSVSTSVRLEKGVNGSNDHHCYIRVQVRDTGQGFLP------QDIPKHFNRGGMILDAKNIKHYSG----TGLPIS || .||.||.. . .||.|.|.| | .. .|. .. ..|..|.|.| |. | .|||. | ... .. . |.| || |. GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYIC KRWLVNLMEGHIWIESDGPGKGSVVTFIVKLQ .| .| ...|.||.|| |.|...|| ..|. RR-IVEQHGGTIWVESEP-GGGTTFTFTLPLE |
|||||||||
HATPase_c | HisK_p.AA | HATPase_c | 465-586 | 26 | 6.8e-19 | 70.02 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 465-586 Range on HMM: 1-130/130 Sequence Identity: 26% (41 aa) GDDRRLVQVLLQITGNAVKFTKE--------------GSVSTSVRLEKGVNGSNDHHCYIRVQVRDTGQGFLP------QDIPKHFNRGGMILD------ || .|| |||. . .||.|.|.| | .. .|. |..|.|.| |. | .|||. | ... | GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMC -AKNIKHYSG----TGLPISKRWLVNLMEGHIWIESDGPGKGSVVTFIVKLQR . . |.| ||.|.|| .|....|.||.| ...|| ..|.| PDSRSRKYGGGLTGLGLSICKR-IVEQHGGTIWVE-------TTFTFTLPLER |
|||||||||
Kinase | HisK_p.AA | HisK | 465-520 | 23 | 4.8e-08 | 25.65 | In-house | 1-80 (164) | Show / Hide |
Range on Protein: 465-520 Range on HMM: 1-80/164 Sequence Identity: 23% (19 aa) GDDRRLVQVLLQITGNAVKFTKEGS--VSTSVRLE----------KGVNGS----NDHHC----------YIRVQVRDTGQG | .|. |.|. . .||.|||..| . ..... | | | .. .|...| ||| | SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKY-N-SIFIQKIQENMVQEQLQQKNLIQISVQDTGCG |
|||||||||
Kinase | HisK_p.AA | HisK | 572-585 | 35 | 0.39916 | 0.7 | In-house | 151-164 (164) | Show / Hide |
Range on Protein: 572-585 Range on HMM: 151-164/164 Sequence Identity: 35% (5 aa) PGKGSVVTFIVKLQ .|||| .| . . VGKGSTFSFYIYNN |