Gene HisK_g (S.moellendorffii)
HisK_g
Species: S.moellendorffii
Alias: HisK_g
External Links:
Annotation:
Sequence
Protein domains of HisK_g.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| HisKA | HisK_g.AA | HisKA | 18-83 | 40 | 5.9e-27 | 96.79 | SMART | 1-89 (89) | Show / Hide |
Range on Protein: 18-83 Range on HMM: 1-89/89 Sequence Identity: 40% (36 aa) AKSEFLANMSHEIRTPLNGIINCTELCLD----------TQTSTEQ-------------QEYLELVRFSAKHLLRIITDILDFSKIEAG ||..||||||||.||||..|. .||..| | . || .|||| .. .|....|.| |.||.|.|||| AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG |
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| HisKA | HisK_g.AA | HisKA | 18-83 | 53 | 3e-26 | 94.45 | Pfam | 1-69 (69) | Show / Hide |
Range on Protein: 18-83 Range on HMM: 1-69/69 Sequence Identity: 53% (37 aa) AKSEFLANMSHEIRTPLNGIINCTELCLD-TQTSTEQ--QEYLELVRFSAKHLLRIITDILDFSKIEAG ||..||||||||.||||..|. .||..| | . || .|||| .. .|....|.| |.||||.|||| AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG |
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| HATPase_c | HisK_g.AA | HATPase_c | 130-244 | 38 | 9.4e-36 | 126.66 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 130-244 Range on HMM: 1-120/120 Sequence Identity: 38% (48 aa) GDPGRLFQVFVNLIGNGIKFTED-GEVVVLAKLQNKTKETVELLFSVNDTGVGIPK------NKQSLLFQAFSQVDS-STTRLYGG--TGLGLVISSKLA ||| || ||. ||..|.||.|. |.. | .. .. .. ..| |.|.|||. ... .|..| ..|. |. | ||| ||||| |. ... GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-----DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIV AAMGGRMWVESE-GQGSTFYFTATFH ..||..||||| |.|.|| || . EQHGGTIWVESEPGGGTTFTFTLPLE |
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| HATPase_c | HisK_g.AA | HATPase_c | 130-249 | 29 | 2.1e-35 | 124.87 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 130-249 Range on HMM: 1-130/130 Sequence Identity: 29% (44 aa) GDPGRLFQVFVNLIGNGIKFTED--------------GEVVVLAKLQNKTKETVELLFSVNDTGVGIPK------NKQSLLFQAFSQVDS--------ST ||| || ||. ||..|.||.|.. |.. | .. ..| |.|.|||. ... .|..| ..|. |. GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-----------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSR TRLYGG--TGLGLVISSKLAAAMGGRMWVESEGQGSTFYFTATFHVPVSV .| ||| ||||| |. ... ..||..||| | ||..|... SRKYGGGLTGLGLSICKRIVEQHGGTIWVE---------TTFTFTLPLER |
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| Kinase | HisK_g.AA | HisK | 130-239 | 26 | 2.1e-22 | 77.4 | In-house | 1-159 (164) | Show / Hide |
Range on Protein: 130-239
Range on HMM: 1-159/164
Sequence Identity: 26% (42 aa)
GDPGRLFQVFVNLIGNGIKFTEDG------EVVVLAKLQNKTKE----------------------TVELLFSVNDTGVGIPKNKQSLLFQAFSQVD---
|| |. |. .|||.| .|||. | . . ....| ... . .|| |||.|.|...| .|..|...|
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH
------SSTTRL---YGGTGLGLVISSKLAAAMG--------GRMWVESE-GQGSTFYF
.. . | ||||.|. .|| .| . |.|| |.||||.|
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSF
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| REC | HisK_g.AA | REC | 264-470 | 12 | 2.5e-11 | 44.89 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 264-470
Range on HMM: 1-150/150
Sequence Identity: 12% (31 aa)
VSSLVVDDN----KTSRDILV------RMLRAWGMV--------VESANGVE-------DALSAFQRAAQRG--------QPFRVLLLDMWLK-------
. |.|||. . |..| |.|. .|. |..| | .|| ..|. ... .|. ....|. .
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG
GTSATDLVKSLQENPSLIQSRSTARPLSGVSSSSQTIHCNRLCNGDHEVEPECPSILIRGHNKLPNGIIHKHRGSPAQSSKSQVAEQNFSTPSEGTKCLD
| . .|.. ..
GMDGIELCRRIR----------------------------------------------------------------------------------------
QNLKDTPMLPIVMLTSLEH-SDAARCKQIGVDVHTSKPIKRALLKRAL
||.|||. .|. |. . |.| .||... | ..
---------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
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| Response_reg | HisK_g.AA | Response_reg | 267-338 | 25 | 3.7e-07 | 28.21 | Pfam | 2-71 (115) | Show / Hide |
Range on Protein: 267-338 Range on HMM: 2-71/115 Sequence Identity: 25% (19 aa) LVVDDNKTSRDILVRMLR-AWGM-VVESANGVEDALSAFQRAAQRGQPFRVLLLDMWLKGTSATDLVKSL-QENP |.|||. . |..|...|. .|. ||..| |.|| .|. . ....|... | . .| . . ...| LIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-----PDLIIMDINMPGMDGLELCRRIRRQHP |
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| Response_reg | HisK_g.AA | Response_reg | 432-471 | 29 | 0.024133 | 10.96 | Pfam | 75-115 (115) | Show / Hide |
Range on Protein: 432-471 Range on HMM: 75-115/115 Sequence Identity: 29% (12 aa) LPIVMLTSLE-HSDAARCKQIGVDVHTSKPIKRALLKRALN .||.|.|. . .|| .. | | . . .||.... |. |.. TPIIMCTAHGDEDDAVEALQAGANDYITKPFDPDELHAAIR |
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| REC | HisK_g.AA | REC | 503-618 | 24 | 8.8e-37 | 129.44 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 503-618 Range on HMM: 1-150/150 Sequence Identity: 24% (39 aa) LKILVAEDN----VVNQRVAM------TLLQKWGHA--------TVLACNGS-------EAVEQSSKEF-------------FDLVLMDVQMP------- ..||...|. |.... ||.|.|. . | .| ||.|. .. .||..||..|| MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG ICDGFQATREIRELEKSSGVRTPIVAMTAHAMSGDGDRCIAAGMDGYISKPLNAKKLKDLL ||....|.|| ||...|||.. | |...||.|.||.|| ... | . . GMDGIELCRRIR----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
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| Response_reg | HisK_g.AA | Response_reg | 505-619 | 29 | 9.2e-31 | 112.75 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 505-619 Range on HMM: 1-115/115 Sequence Identity: 29% (35 aa) ILVAEDNVVNQRVAMTLLQ-KWGH-ATVLACNGSEAVEQSSKEFFDLVLMDVQMPICDGFQATREI-RELEKSSGVRTPIVAMTAHAMSGDGDRCIAAGM .|...|. ..... ..|. |.| . .| .| ||.|. .. .||..||..|| .||....|.| |... ... |||...|||.. | ... ||. VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRRQHP-HPQ--TPIIMCTAHGDEDDAVEALQAGA DGYISKPLNAKKLKDLLE ..||.|| . .|.. .. NDYITKPFDPDELHAAIR |
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