Gene HisK_n (S.moellendorffii)
HisK_n
Species: S.moellendorffii
Alias: HisK_n
External Links:
Annotation:
Sequence
Protein domains of HisK_n.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| HisKA | HisK_n.AA | HisKA | 486-552 | 33 | 1.8e-22 | 81.93 | SMART | 1-89 (89) | Show / Hide |
Range on Protein: 486-552 Range on HMM: 1-89/89 Sequence Identity: 33% (30 aa) YKSQFLANMSHELRTPMAAVIGLLDILLT---------DACLTVEQI-------------AIVSQIRHCSTALLRLLNNILDLSKVESG |.|||||||||||||..|..|....|.. .. |. ||. ....|.... ..||.|..||||. |.| AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG |
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| HisKA | HisK_n.AA | HisKA | 486-552 | 42 | 4.2e-21 | 76.52 | Pfam | 1-69 (69) | Show / Hide |
Range on Protein: 486-552 Range on HMM: 1-69/69 Sequence Identity: 42% (29 aa) YKSQFLANMSHELRTPMAAVIGLLDILLTDACLTVEQ--IAIVSQIRHCSTALLRLLNNILDLSKVESG |.|||||||||||||..|..|....|.... |. || ... |.... ..||.|..||.|. |.| AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG |
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| HATPase_c | HisK_n.AA | HATPase_c | 597-725 | 30 | 3.8e-30 | 107.15 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 597-725 Range on HMM: 1-120/120 Sequence Identity: 30% (43 aa) GDLTRTVQIFANLIGNSIKFTSS-GYITIRGWAEPFVSRYEPLEASGGHIEKFLLWFEVDDSGCAGIDP------SKWETVFDSFVQADT-STSRTHGG- || .| .|.. ||..|.||.| . | ||.| .... ....| |.|. ||.| . ...|. |...| |. | .|| GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-----------------DHVRITVEDNGP-GIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGG -TGLGLCIVRSLVSKMGGEIKVVKKEEPGTLMRFYLMYD ||||| |.| .| ..||.| | ... || ..|.| . LTGLGLYICRRIVEQHGGTIWVESEPGGGTTFTFTLPLE |
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| HATPase_c | HisK_n.AA | HATPase_c | 597-726 | 26 | 2.5e-27 | 98.05 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 597-726 Range on HMM: 1-130/130 Sequence Identity: 26% (42 aa) GDLTRTVQIFANLIGNSIKFTSS--------------GYITIRGWAEPFVSRYEPLEASGGHIEKFLLWFEVDDSGCAGIDP------SKWETVFDSFVQ || .| |.. ||..|.||.| . | ||.| . ...| |.|. ||.| . ...|. |.. GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-----------------------RITVEDNGP-GIPPEMHKSIEDIPRIFEPFYR ADT--------STSRTHGG--TGLGLCIVRSLVSKMGGEIKVVKKEEPGTLMRFYLMYDS .| |.|| .|| ||||| |....| ..||.|.| | ..|.| TDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGTIWVE------TTFTFTLPLER |
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| Kinase | HisK_n.AA | HisK | 597-725 | 22 | 3.6e-13 | 44.15 | In-house | 1-164 (164) | Show / Hide |
Range on Protein: 597-725 Range on HMM: 1-164/164 Sequence Identity: 22% (39 aa) GDLTRTVQIFANLIGNSIKFT------SSGYITIR---------GWAEPFVSRYEPLEASGGHIEKF----------LLWFEVDDSGCAGIDPSKWETVF | | || |||.|..||| ..|||.| .|. ... .|.. |... | |.|| |..... . | SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNI-------KYN--SIFIQKIQENMVQEQLQQKNLIQISVQDTGC-GMPEEQQKKIF DSFVQADT-------STSRTHG-----GTGLGLCIVRSLVSKMG--------GEIKVVKKEEPGTLMRFYLMYD . | . |. ... .. | |||| | ..|. ..| ..|.|. .. |. ||. . KMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN |
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| REC | HisK_n.AA | REC | 981-1108 | 30 | 2.2e-36 | 128.1 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 981-1108 Range on HMM: 1-150/150 Sequence Identity: 30% (50 aa) IHILLAEDT----PVIQKVAV------VLLKKLGAT--------VVAVADGQ-------AAVEAWKGSL--KDQAVVDEERKPFDLILMDCQMP------ ..||...| |||... ||.|.| . |... ||. .|.|... |..| | ..|.|||.||..|| MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED -RMDGYGATREIRKAEEGSGSHVPIVALTAHAMSSDEERCLEVGMDAYLTKPIDCKLMATTI .|||. ..|.|| ||..||||.. .| .|.||.|.|.|.|||.| . . .| GGMDGIELCRRIR----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
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| Response_reg | HisK_n.AA | Response_reg | 983-1109 | 30 | 1e-27 | 101.81 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 983-1109 Range on HMM: 1-115/115 Sequence Identity: 30% (39 aa) ILLAEDTPVIQKVAVVLLK-KLGA-TVVAVADGQAAVEAWKGSLKDQAVVDEERKPFDLILMDCQMPRMDGYGATREIRKAEEGSGSHVPIVALTAHAMS .|...| |..... . .|. | | | ...||..|.| | ... .|||.||..||.|||. ..|.||.... ...||...|||.. VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW------------QEHHPDLIIMDINMPGMDGLELCRRIRRQHP--HPQTPIIMCTAHGDE SDEERCLEVGMDAYLTKPIDCKLMATTIL .| ...|..|.. |.|||.| . . | DDAVEALQAGANDYITKPFDPDELHAAIR |
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