Gene HisK_e (S.moellendorffii)

HisK_e

Species: S.moellendorffii
Alias: HisK_e
External Links:
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
HisK_e.AA Protein None 838 None Fasta, JSON
HisK_e.NA RNA None 2517 None Fasta, JSON

Protein domain

Protein domains of HisK_e.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
MASE1 HisK_e.AA MASE1 140-354 20 2e-05 21.71 Pfam 92-322 (322) Show / Hide 
Range on Protein: 140-354
Range on HMM: 92-322/322
Sequence Identity: 20% (50 aa)

TLEVHFCSWMVRRFLCSETRLIPT---IESLGDALWYFLVTCFLSAPFEATIALIE-CVGRMVPWKEFTICWATWWLGVVAASITVSPFVLH--SFVWQP
|||. |. | .|... .. |.  .   | .. .... .. .......  |.|.|.  ..   .||  |.. |.||||| . . ..| ||..    . ||.
TLEAFFGWWWLRWWWPRRHRWQRLQNHIWQRIFWCRFCWFGAIICCLWSAIIGLACLYWFGKIPWAPFAWSWWTWWLGDATGVLVVTPFCYLWWHWWWQR

KPGMFRPG---KIVEIFLVGFITVLLLITV----YTLVIPTYVK-PLP------YLLFPVIVYSAFRFNRMGWAFILCGISLFCTWSTVKKKGALYNISG
  ..  .     .|.  |..|...|...      .....|.. . .||      |...|... .|.||  .| | ... .... .|.|         ..|
HWWPAWWWFDHHPVACKLLHFFWYLWFCILSTWRQWWCCPFEFNYFLPYTQWTFYCMMPPMLWAAWRFGWQGAALATLLWWVIIIWFT---------AQG

GGP-TVEPRIVMQ----VELFVSVSSAVAVSLAAAVREKH
.|| ....    |    . .|..... .|  ..||..| .
QGPFNQDSGYQYQQAFELQMFLAIQAMTALFMGAAIQEQR
HisKA HisK_e.AA HisKA 398-463 44 6.3e-23 82.87 Pfam 1-69 (69) Show / Hide 
Range on Protein: 398-463
Range on HMM: 1-69/69
Sequence Identity: 44% (31 aa)

AKSDFLANMSHEIRTPIHGILGMSALVLG-TSLTDEQ--KENMTTVSECAELLLHIINSILDLGKIEAG
||..||||||||.|||...|.|.. | .  | |..||  .|   |. ..|. ....|| .||. .||||
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA HisK_e.AA HisKA 398-463 35 1.1e-22 82.61 SMART 1-89 (89) Show / Hide 
Range on Protein: 398-463
Range on HMM: 1-89/89
Sequence Identity: 35% (32 aa)

AKSDFLANMSHEIRTPIHGILGMSALVLG----------TSLTDEQ-------------KENMTTVSECAELLLHIINSILDLGKIEAG
||..||||||||.|||...|.|.. | .           | |..||             .|   |. ..|. ....|| .||| .||||
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HATPase_c HisK_e.AA HATPase_c 510-640 34 6.6e-37 130.67 Pfam 1-120 (120) Show / Hide 
Range on Protein: 510-640
Range on HMM: 1-120/120
Sequence Identity: 34% (48 aa)

GDSGKLRQCLLNLVGNALKFTPD-GEVRVEVSVHRFGMQDDSVLSRLNASQWSDMLEMMLEISDSGIGISK------NKLKDVFKPFTQADA-SISRLYG
||   |.| ..|||.||.|.||  |...|.|.                        .  ....|.|.||..       ..  .| || ..|. |  | ||
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD--------------------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYG

G--TGLGLCVVQRFVELMGGHILVESEYGKGSSFYIVLPYL
|  ||||| ...|.||..||.| |||| |.|. | . ||  
GGLTGLGLYICRRIVEQHGGTIWVESEPGGGTTFTFTLPLE
HATPase_c HisK_e.AA HATPase_c 510-641 30 1.3e-36 128.9 SMART 1-130 (130) Show / Hide 
Range on Protein: 510-641
Range on HMM: 1-130/130
Sequence Identity: 30% (48 aa)

GDSGKLRQCLLNLVGNALKFTPD------------GEVRVEVSVHRFGMQDDSVLSRLNASQWSDMLEMMLEISDSGIGISK------NKLKDVFKPFTQ
||   ||| |.||..||.|.||.            |. |..|.||                         ....|.|.||..       ... .| || .
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH------------------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYR

ADA--------SISRLYGG--TGLGLCVVQRFVELMGGHILVESEYGKGSSFYIVLPYLL
.|         | || |||  ||||| ...|.||..||.| ||      . |.. ||  .
TDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGTIWVE------TTFTFTLPLER
Kinase HisK_e.AA HisK 510-637 20 4e-21 72.84 In-house 1-161 (164) Show / Hide 
Range on Protein: 510-637
Range on HMM: 1-161/164
Sequence Identity: 20% (36 aa)

GDSGKLRQCLLNLVGNALKFT------PDGEVRVEVS--------------VHRFGMQDDSVLSRLNASQWSDML-------EMMLEISDSGIGISKNKL
 |  ...| |.||..||||||      . | ....|.              .  .  .           . .  .            ..|.|.|......
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQEN-----------M-V--QEQLQQKNLIQISVQDTGCGMPEEQQ

KDVFKPFTQADA---------SISRL---YGGTGLGLCVVQRFVELMG--------GHILVESEYGKGSSFYIVL
|  ||.| . |.         . ..      | |||| . .......|        ..| |.||.||||.|....
KKIFKMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYI
Response_reg HisK_e.AA Response_reg 760-812 29 1.9e-11 43.59 Pfam 1-53 (115) Show / Hide 
Range on Protein: 760-812
Range on HMM: 1-53/115
Sequence Identity: 29% (16 aa)

ILLVEDNLVNQKVASRLLQ-KHGH-IVTVVGDGVQAIAAVDANRDNIDLILMDIQ
.|.|.|. .....  ..|. |.|  .|... || .|.. .....  .|||.|||.
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH--PDLIIMDIN