Gene RSK-p2_c-1 (S.moellendorffii)

RSK-p2_c-1

Species: S.moellendorffii
Alias: RSK-p2_c-1
External Links:
Annotation:

Classification

Group: AGC
Family: RSK
Subfamily: RSK-p2

Sequence

Name Sequence Type Origin Length Description Download
RSK-p2_c-1.AA Protein None 430 None Fasta, JSON
RSK-p2_c-1.NA RNA None 1293 None Fasta, JSON
RSK-p2_c-1.kin_dom Protein Kinase Domain None 342 None Fasta, JSON

Protein domain

Protein domains of RSK-p2_c-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RSK-p2_c-1.AA AGC 52-393 24 4.1e-127 330.34 In-house 1-395 (395) Show / Hide 
Range on Protein: 52-393
Range on HMM: 1-395/395
Sequence Identity: 24% (115 aa)

FKLLQRLGSGDIGSVYLSELR------GFRCLFAMKVMDKTA---LAARNKLLRAATE------------RSILEKLD----------HPFLPT-LYAHF
|..|  .| |  | ||| . .      .   ..||||..|     .  .|.. .. ||            | ||||..          |||.   |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

DTANF--SCLIMEYCP---------GG-DLHTLRQRQ-LTKRFDNEAVRFYAAE-------ILLALEYLHM-MGVVYRD-LKPENVLVRHDGHIMLSDFD
 . .    ...|||.|         || .|..  | .   .||| |..||||||       |.|||||||  ||...|| |||||.|  .||||.|.|| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSLICDVSP-------------------------TVIQSPPPGTAARRRAPSFSSSSSSTGKLGRLGGGASPSCILPACVAPCTVDRPMPPAGQLRSTRV
|. .   ..                         |                                                                .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDT-N--------------------------------------------------------------K

NPLPELVAEPT-----------GARSMSFVG--THEYLAPEIISGYGHGSAVDWWT--LGIFLFEMFHGRTPFKGGDNE----------STLVNVL----
   |.   .             ..|  .|.|  |.||.||||.    .| |.|||.  ||....||  |..|| | ...           .  ...    
-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRY

--TKPLEFG-----GAAEGVELGEDARSLIRGLLAKDPAKRIASAR------GAVEIKQHPFF
  .....|         | ... ..|..||..|| |||.||. . .      || |||.||.|
FINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase RSK-p2_c-1.AA RSK 55-393 29 6.1e-86 291.82 In-house 1-278 (278) Show / Hide 
Range on Protein: 55-393
Range on HMM: 1-278/278
Sequence Identity: 29% (104 aa)

LQRLGSGDIGSVYLSELR---GFRCLFAMKVMDKTALAARNK-LLRAATERSILEKLD-HPFLPTLYAHFDTANFSCLIMEYCPGGDLHTLRQRQLTK-R
|. || |. |.|.|         . ..|||| .|  ...|.| . .. |||.|||    |||. ||.  |.|     ||||||.||.| |  |.. ..  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FDNEAVRFYAAEILLALEYLHMMGVVYRDLKPENVLVRH---DGHIMLSDFDLSLICDVSPTVIQSPPPGTAARRRAPSFSSSSSSTGKLGRLGGGASPS
|. . ..||.||| ||.|.||  |...|||||||.|  .   .|||.|.||... .                                            
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------------------------------------------

CILPACVAPCTVDRPMPPAGQLRSTRVNPLPELVAEPT-GARSMSFVGTHEYLAPEIIS----GYGHGSAVDWWTLGIFLFEMFHGRTPFKG---GDNES
                                    .  . . |.|..|.||.|||..     . ||. |.|||.||. ..||. |..||.|    . . 
-----------------------------------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKE

TLVNVLTKPLEFGGAAEGVELGEDARSLIRGLLAKDPAKRIAS-ARGAVEIKQHPFF
.. ..... . ... .   .| ..|..|||..| .||.||. .  ..| ||||||.|
IMKRIQKGKFSLTMPNW-QYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase RSK-p2_c-1.AA S_TKc 52-393 23 1.5e-84 288.12 SMART 1-231 (231) Show / Hide 
Range on Protein: 52-393
Range on HMM: 1-231/231
Sequence Identity: 23% (84 aa)

FKLLQRLGSGDIGSVYLSELRGFRCLFAMKVMDKTALAARNKLLRAATERSILEKLDHPFLPTLYAHFDTANFSCLIMEYCPG--GDLHTLRQRQLTKR-
...|. .|.|  |.||.   ..   ..|.|...           ..  |..||.| .||.. .|| .|.. .. ...||||.|  |||... ... ... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDNEAVRFYAAEILLALEYLHMMGVVYRDLKPENVLVRHDGHIMLSDFDLSLICDVSPTVIQSPPPGTAARRRAPSFSSSSSSTGKLGRLGGGASPS
   |.   .|||...|..||||.| .|...|||||||.|. .  ||...|| |. .                                            
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------

CILPACVAPCTVDRPMPPAGQLRSTRVNPLPELVAEPTGARSMSFVGTHEYLAPEIISGYGHGS-AVDWWTLGIFLFEMFHGRTPFKGGDNESTLVNVLT
                                          ..|.|| .|.|||..   |.|  ..||| .|. |.||. |..||    .. .. ... 
------------------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG

KPLEFGGAAEGVELGEDARSLIRGLLAKDPAKRIASARGAVE----IKQHPFF
               ..|...||..| |||.||. .|  | .    ||.||.|
--------------SPEAKDFIRKCLQKDPEKRP-TA-EALQDEWDIKCHPWF
Kinase RSK-p2_c-1.AA AktR 52-393 30 8e-80 271.5 In-house 1-268 (268) Show / Hide 
Range on Protein: 52-393
Range on HMM: 1-268/268
Sequence Identity: 30% (107 aa)

FKLLQRLGSGDIGSVYLSELR-GFRCLFAMKVMDKTALAARNKLLRAATERSILE-KLDHPFLPTLYAHFDTANFSCLIMEYCPGGDLHTLRQRQLTKRF
|.... ||.|  | ||| . .     ..|||. .|. .  ||.  .. ||| |.| . .|||.  |.  | | . . .||||||||.| .  ...  |.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKK--KKF

DNEAVRFYAAEILLALEYLHMM-GVVYRDLKPENVLVRHDGHIMLSDFDLSLICDVSPTVIQSPPPGTAARRRAPSFSSSSSSTGKLGRLGGGASPSCIL
..| .|||.|.|||||||||    ..|||||||| |   |||. ..|| ||                                                 
SEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK------------------------------------------------

PACVAPCTVDRPMPPAGQLRSTRVNPLPELVAEPTGARSMSFVGTHEYLAPEIISG-YGHGSAVDWWTLGIFLFEMFHGRTPFKGGDNESTLVNVLTKP-
                             .. .    .  ||.||.||.|||.|    ||. .||||..|||..||  | .||  ....  . . ..|. 
----------------------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQ

LEFGGAAEGVELGEDARSLIR-GLLAKDPAKRIA-SARGAVEIKQHPFF
..|    . ... . ...||  .|| |.| ||.  .. |. ||| ||.|
NKF---PYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase RSK-p2_c-1.AA RSK-Unclassified 52-199 43 2.5e-64 200.8 In-house 1-148 (283) Show / Hide 
Range on Protein: 52-199
Range on HMM: 1-148/283
Sequence Identity: 43% (65 aa)

FKLLQRLGSGDIGSVYLSELRGFRCLFAMKVMDKTALAARNKLLRAATERSILEKLDHPFLPTLYAHFDTANFSCLIMEYCPGGDLHTLRQRQLTKRFDN
|     .| ||.| ||| . ..   ..||||. |  .  .||  .. ||. |.   .|||  |||  | |     |.||||.|||.    |   .|.|  
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

EAVRFYAAEILLALEYLHMMGVVYRDLKPENVLVRHDGHIMLSDFDLS
. |||||.|. .||||||  ...||||||.|..  ..||.||.|||||
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLS
Kinase RSK-p2_c-1.AA RSK-Unclassified 284-393 44 9.3e-48 147.8 In-house 176-283 (283) Show / Hide 
Range on Protein: 284-393
Range on HMM: 176-283/283
Sequence Identity: 44% (49 aa)

GARSMSFVGTHEYLAPEIISGYGHGSAVDWWTLGIFLFEMFHGRTPFKGGDNESTLVNVLTKPLEFGGAAEGVELGEDARSLIRGLLAKDPAKRIASARG
| |  ||.|| ||||||.| . ||. ||||||||| ..||  | .|..|   . |  |...... |    .  ..  ..|.||. || . ||||  . .|
GFRTNSFCGTEEYLAPEMIRRCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKF---PHDSYISNNCRDLIKKLLQRNPAKRLGCKMG

-AVEIKQHPFF
 | .||.||||
DADDIKRHPFF
Kinase RSK-p2_c-1.AA Akt 52-196 42 3.6e-45 142.28 In-house 1-145 (264) Show / Hide 
Range on Protein: 52-196
Range on HMM: 1-145/264
Sequence Identity: 42% (62 aa)

FKLLQRLGSGDIGSVYLSELRGFRCLF-AMKVMDKTALAARNKLLRAATERSILEKLDHPFLPTLYAHFDTANFSCLIMEYCPGGDLHTLRQRQLTKRFD
| .|  ||.|  | |.| .      .. ||||  |  . ..|..  . ||| ||.. .|||.  |.  | |..  ...|.||.||.| .. ||.  .||.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRK--RRFS

NEAVRFYAAEILLALEYLHMMGVVYRD-LKPENVLVRHDGHIMLSDF
 .  |||.||| ||.|.|| ....||| |||||.|. .|||| | ||
EDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDF
Kinase RSK-p2_c-1.AA PKA 52-196 37 7.6e-40 138.69 In-house 1-145 (263) Show / Hide 
Range on Protein: 52-196
Range on HMM: 1-145/263
Sequence Identity: 37% (55 aa)

FKLLQRLGSGDIGSVYLSELRGFRCLFAMKVMDKTALAARNKLLRAATERSILEKLDHPFLPT-LYAHFDTANFSCLIMEYCPGGDLHTLRQRQLTKRFD
|...| ||.|  | |.|   ..  . .|||...|.    ..   .  .|..||  ..|||. . .|..| ....  ..|||.|||.. .  ..   .||.
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKS--GRFS

NEAVRFYAA-EILLALEYLHMMGVVYRDLKPENVLVRHDGHIMLSDF
|   .|||| .| ||||||| .  .|||||||| |   .||| . ||
NPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDF
Kinase RSK-p2_c-1.AA SGK 289-393 42 1.9e-38 116.01 In-house 184-283 (283) Show / Hide 
Range on Protein: 289-393
Range on HMM: 184-283/283
Sequence Identity: 42% (45 aa)

SFVGTHEYLAPEIISGYGHGSAVDWWTLGIFLFEMFHGRTPFKGGDNESTLVNVLTKPLEFGGAAEGVELGEDARSLIRGLLAKDPAKRIASARGAVEIK
.| || ||||||.. . .|. .|||| ||..|.|| .|  ||   . .    | . .|| .           ||..|| |||.||| ||  ..|.. |||
TFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPP-----QMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIK

QHPFF
.||||
NHPFF
Kinase RSK-p2_c-1.AA Pkinase 52-199 31 4.9e-38 135.57 Pfam 1-159 (293) Show / Hide 
Range on Protein: 52-199
Range on HMM: 1-159/293
Sequence Identity: 31% (52 aa)

FKLLQRLGSGDIGSVYLSELRGFRCLFAMKVMDKTALAARNKLLRAAT---ERSILEKLDHPFLPTLYAHFDTANFSCLIMEYCPGG----DLH----TL
.......|||  |.||.   .| ....|.|...|    .. . .....   | .|. .|.||.  .||  | . .  ...||||.||    ||.    | 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-

RQRQLTKRF--DNEAVRFYAAEILLALEYLHMMGVVYRDLKPENVLVRHDGHI----MLSDFDLS
   .  ..|  . . ..||. .|| .|||.| ||...|||||||.|. ..|||     ..|| |.
---WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA
Kinase RSK-p2_c-1.AA SGK 52-199 33 1.7e-37 113.06 In-house 1-172 (283) Show / Hide 
Range on Protein: 52-199
Range on HMM: 1-172/283
Sequence Identity: 33% (59 aa)

FKLLQRLGSGDIGSVYLSELRGF------------------RCLFAMKVMDKTALA-------ARNKLLRAATER-SILEKLDHPFLPTLYAHFDTANFS
|..|. .| |  | ||. .  .                     ..||||  | .         ....     .||  || .. |||.  |   | |.   
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

CLIMEYCPGGDLHTLRQRQLTKRFDNEAVRFYAAEILLALEYLHMMGVVYRDLKPENVLVRHDGHIMLSDFDLS
 . |.|  ||..    ||   |.|    .||||||| .||||||   ..||||||||.|  |.||. | || |.
YFVMDYVNGGEMFYHLQRE--KHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLC
Kinase RSK-p2_c-1.AA Ciliate-E2 52-203 26 1.1e-36 123.42 In-house 1-207 (365) Show / Hide 
Range on Protein: 52-203
Range on HMM: 1-207/365
Sequence Identity: 26% (57 aa)

FKLLQRLGSGDIGSVYLSELRGFRCLFA-----------------------MKVMDKTALAARNKLLRAA----------TERSILEKLDHPFLPTLYAH
.|... .|.|  ||||. . .  ...||                       ||.| |  . . .. ..             |..|||.|.||..  .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FD--TANFSCLIMEYCPGGDLHT-LRQR----------------QLTKRFDNEAVR-------FYAAEILLALEYLHMMG-VVYRDLKPENVLVRHDGHI
|   . |   |.|||| ||||   ....                .  |..  . ..       ||.|.|.|||||||  . ...||.||||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

MLSDFDLSLICD
 ..|| || ..|
KIIDFGLSKKYD
Kinase RSK-p2_c-1.AA RSK 52-199 34 2.3e-36 127.15 In-house 1-152 (271) Show / Hide 
Range on Protein: 52-199
Range on HMM: 1-152/271
Sequence Identity: 34% (54 aa)

FKLLQRLGSGDIGSVYLSELR---GFRCLFAMKVMDKTALAARNKLLRAATERSILEKLDHPFLPTLYAHFDTANFSCLIMEYCPGGDLHTLRQRQLTKR
. |.. .| |  . ||.         . ..|||. .| ..... .  .. .|| ||.  .|||  .|.  |...    .||. . |||| .  ..|  | 
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQ--KM

FDNEAVRFYAAEILLALEYLHMMGVVYRDLKPENVLVRHD----GHIMLSDFDLS
|  . |.||.|||.||.||||  |.|.|||||||.|.  .    ||| . || ..
FSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFA
Kinase RSK-p2_c-1.AA MAST 52-199 39 1.2e-35 112.13 In-house 1-146 (334) Show / Hide 
Range on Protein: 52-199
Range on HMM: 1-146/334
Sequence Identity: 39% (58 aa)

FKLLQRLGSGDIGSVYLSELRGFRCLFAMKVMDKTALAARNKLLRAATERSILEKLDHPFLPTLYAHFDTANFSCLIMEYCPGGDLHTLRQRQLTKRFDN
|.    .. |  | ||| . .  . .|||||..|  .. .| .    .|| ||. .. ||   ..  | |.|  |..|||  |||. .|  . .. .|| 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASL-LHMYG-YFDE

EAVRFYAAEILLALEYLHMMGVVYRDLKPENVLVRHDGHIMLSDFDLS
. ...| ||. |.||||| .| | |||||.|.|   .||| | || ||
WMAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase RSK-p2_c-1.AA MAST 291-393 40 9.8e-34 105.88 In-house 225-334 (334) Show / Hide 
Range on Protein: 291-393
Range on HMM: 225-334/334
Sequence Identity: 40% (45 aa)

VGTHEYLAPEIISGYG-HGSAVDWWTLGIFLFEMFHGRTPFKGGDNESTLVNVLTKP---LEF--GGAAE-GVELGEDARSLIRGLLAKDPAKRIASARG
.|| .|.|||.| | | || .|||| .|| ..| . | .|| . . | .  |.| .     |.  ||  . . .. ..|. ||. ||. || ||...  |
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

AVEIKQHPFF
| |.||||||
ADEVKQHPFF
Kinase RSK-p2_c-1.AA RSK 288-393 32 6.6e-29 100.38 In-house 163-271 (271) Show / Hide 
Range on Protein: 288-393
Range on HMM: 163-271/271
Sequence Identity: 32% (36 aa)

MSFVGTHEYLAPEIISGYGHGSAVDWWTLGIFLFEMFHGRTPFKGGDNESTLVNVLTKPLEF----GGAAEGVELGEDARSLIRGLLAKDPAKRIAS-AR
|.| .| .|.|||...  ||. |.||| .|. ..|| .|.||| ....... .. .  .|      .|  .   . . | .|.|..|  ||..|  . . 
MTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWD--FISDEAKDLLRMMLHRDPHNRLGAGPN

GAVEIKQHPFF
|. .|||||.|
GVEQIKQHPWF
Kinase RSK-p2_c-1.AA Pkinase 281-393 29 9.9e-29 102.67 Pfam 164-293 (293) Show / Hide 
Range on Protein: 281-393
Range on HMM: 164-293/293
Sequence Identity: 29% (40 aa)

EPTGARSMSFVGTHEYLAPEIIS-GYGHGSAVDWWTLGIFLFEMFHGRTPFKGG------DNESTLVNVLTKPLEFGGA-----------------AEGV
.  .   ..|.|| .|.|||.|  | ..|..||.| .|. |.||. ||.||.|       |    ..... .||.|                       .
Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-H

ELGEDARSLIRGLLAKDPAKRIASARGAVEIKQHPFF
.. |.....|...|.|||.||.     | .|.|||.|
NWSEECKDFIKWCLCKDPKKRPT----AEQILQHPWF
Kinase RSK-p2_c-1.AA Ciliate-E2 289-393 25 1e-27 92.22 In-house 246-365 (365) Show / Hide 
Range on Protein: 289-393
Range on HMM: 246-365/365
Sequence Identity: 25% (33 aa)

SFVGTHEYLAPEIIS---------GYGHGSAVDWWTLGIFLFEMFHGRTPFKGGDNESTLVNVLTKPLEFGGAA-------------EGVELGEDARSLI
...|| .|.||||..         . |.. ..|.| ||. |.||  |..||        . . . ....|  .              .  .. ...  ||
TICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLI

RG----LLAKDPAKRIASARGAVEIKQHPFF
.     .| ||| |||    |. .|..||.|
KKFGKRMLQKDPEKRIT---GWEQILNHPWF
Kinase RSK-p2_c-1.AA PKA 292-393 37 2.9e-25 90.27 In-house 160-263 (263) Show / Hide 
Range on Protein: 292-393
Range on HMM: 160-263/263
Sequence Identity: 37% (41 aa)

GTHEYLAPEIISGY-GHGSAVDWWTLGIFLFEMFHGRTPFKGG--DNESTLVNVLTKPLEFGGAAEGVELGEDA---RSLIRGLLAKDPAKRI-ASARGA
|| ||||||||..  ||| .||||.|||  .||  | .||     |  ..    .   ..|       ..  ||   ..||. ||..|. ||.     |.
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKF-----PRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGV

VEIKQHPFF
  || |..|
NDIKNHKWF
Kinase RSK-p2_c-1.AA Akt 288-330 59 1.8e-23 71.86 In-house 160-203 (264) Show / Hide 
Range on Protein: 288-330
Range on HMM: 160-203/264
Sequence Identity: 59% (26 aa)

MSFVGTHEYLAPEIISGYGHGSAVDWWT-LGIFLFEMFHGRTPF
..| || |||||||..| ||. |||||. ||....|| .|| ||
KTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPF
Kinase RSK-p2_c-1.AA Akt 361-393 50 6.5e-14 40.79 In-house 231-264 (264) Show / Hide 
Range on Protein: 361-393
Range on HMM: 231-264/264
Sequence Identity: 50% (17 aa)

DARSLIRGLLAKDPAKRIA-SARGAVEIKQHPFF
....||.||| ||| ||      .| |||.||.|
ECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase RSK-p2_c-1.AA TyrKc 52-387 15 1.6e-08 -84.72 SMART 1-280 (280) Show / Hide 
Range on Protein: 52-387
Range on HMM: 1-280/280
Sequence Identity: 15% (61 aa)

FKLLQRLGSGDIGSVYLSELRGFRCLFAMKVMDKTALAARNKLLRAATERSILEKL--DHPFLPTLYAHFDTA-------NFSCLIMEYCPGGDLHTLRQ
 .|.. ||.|  | ||. ...      | |.. . |   |  ..|   | .|. ||  .|| .  ||.   .           ...|||.|.|||.   .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMR---EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RQLTKRFDNEAVRFYAAEILLALEYLHMMGVVYRDLKPENVLVRHDGHIMLSDFDLSLICDVSPTVIQSPPPGTAARRRAPSFSSSSSSTGKLGRLGGGA
.   | . ..    ..  |    |||| .... |||   |.|| ...                                                     
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------------------------------------------------

SPSCILPACVAPCTVDRPMPPAGQLRSTRVNPLPELV-------AEPTGAR-------SMSFV----GTHE-----YLAPEIISGYGHGSAVDWWTLGIF
                                    |       .   .         ..  .    |..       .||| |  .   .. | |  |. 
-----------------------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVC

LFEMF-HGRTPFKG-----GDNESTLVNVLTK-----PLE-----FGGAAEGVELGEDARSLIRGLLAKDPAKRIASARGAVEI
..|.|  | .|  |      .|.  . .| .      | .     |      |.  ..  ....   . ||..|   .    ..
MWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF------VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF