Gene RSK-p2_a-2 (S.moellendorffii)

RSK-p2_a-2

Species: S.moellendorffii
Alias: RSK-p2_a-2
External Links:
Annotation:

Classification

Group: AGC
Family: RSK
Subfamily: RSK-p2

Sequence

Name Sequence Type Origin Length Description Download
RSK-p2_a-2.AA Protein None 558 None Fasta, JSON
RSK-p2_a-2.NA RNA None 1677 None Fasta, JSON
RSK-p2_a-2.kin_dom Protein Kinase Domain None 336 None Fasta, JSON

Protein domain

Protein domains of RSK-p2_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RSK-p2_a-2.AA AGC 141-476 24 4.6e-138 359.33 In-house 1-395 (395) Show / Hide 
Range on Protein: 141-476
Range on HMM: 1-395/395
Sequence Identity: 24% (113 aa)

FRLLKRLGCGDIGSVYLAELR------STSCHFAMKVMDKAS---LASRKKLLRAQTE------------KEILQSLD----------HPFLPT-LYTHF
|..|| .| |  | |||.. .      .|   .||||..|.    .  .... ...||            ..||. ..          |||.   |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETDKF--SCLVMEFCM---------GG-DLHTLRQRQ-PGKHFTEQAAKFYASE-------VLLSLEYLHM-LGVVYRD-LKPENVLVREDGHIMLSDFD
....    ..|||..          || .|..  | .   ..|.|..|.|||.|       ..| |||||  .|...|| |||||.|  |||||.|.|| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSLRCVVSP---------------------TLVKSSMDGDKRGPAYCIQPACVQPSCIQPACVVQPSCLLPRFLSKAKSKKSRKPRNDVGNQVSPLPELV
|. . . ..                     .    .|| . .                                                  .   |.  
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKS----NMD-T-N--------------------------------------------------K-CNPNNW

AEPT-----------GARSMSFVG--THEYLAPEIIKGEGHGSAVDWWT--FGIFLYELLHGKTPFKGSG---------NRATLFNVVG-------QPLK
 .             ..|  .|.|  |.||.||||.    .| |.|||.  .|...||.| |..|| |           |.. .|. .        ...|
QRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVK

FPET--------SHVSFAARDLIRGLLVKDPQHRLASKR------GATEIKQHPFF
||          ...|  |.|||..||.||| .|| ...      || |||.||.|
FPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase RSK-p2_a-2.AA AktR 141-476 30 6.7e-93 314.93 In-house 1-268 (268) Show / Hide 
Range on Protein: 141-476
Range on HMM: 1-268/268
Sequence Identity: 30% (105 aa)

FRLLKRLGCGDIGSVYLAELR-STSCHFAMKVMDKASLASRKKLLRAQTEKEILQ-SLDHPFLPTLYTHFETDKFSCLVMEFCMGGDLHTLRQRQPGKHF
|...| || |  | |||.. .  .   .|||. .|  .  |..  ...||. |..   .|||.  |.  |.|.. . ..||.| ||.| .  ...  |.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKK--KKF

TEQAAKFYASEVLLSLEYLHML-GVVYRDLKPENVLVREDGHIMLSDFDLSLRCVVSPTLVKSSMDGDKRGPAYCIQPACVQPSCIQPACVVQPSCLLPR
.|. |.||....|| |||||    ..|||||||| |  ||||. ..|| ||                                                 
SEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK------------------------------------------------

FLSKAKSKKSRKPRNDVGNQVSPLPELVAEPTGARSMSFVGTHEYLAPEIIKG-EGHGSAVDWWTFGIFLYELLHGKTPFKGSGNRATLFNVVGQP-LKF
                          .. .    .  ||.||.||.|||.|.  .||. .||||.||||.||.. | .||  . ..  ...   .. .||
-------------------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKF

PETSHVSFAARDLIR-GLLVKDPQHRLA-SKRGATEIKQHPFF
|..| .|....|||  .|| |.|..||  .. |..||| ||.|
PYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase RSK-p2_a-2.AA S_TKc 141-476 24 1.4e-88 301.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 141-476
Range on HMM: 1-231/231
Sequence Identity: 24% (86 aa)

FRLLKRLGCGDIGSVYLAELRSTSCHFAMKVMDKASLASRKKLLRAQTEKEILQSLDHPFLPTLYTHFETDKFSCLVMEFCMG--GDLHTLRQRQPGKH-
...|. .| |  |.||..  ..|  ..|.|...           ... | .||.. .||.. .|| .|.. .. ..|||.| |  |||... ......  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTEQAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVREDGHIMLSDFDLSLRCVVSPTLVKSSMDGDKRGPAYCIQPACVQPSCIQPACVVQPSCL
   |.|  |.||. .... |||.| .|...|||||||.|. |  ||...|| |. .                                            
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------

LPRFLSKAKSKKSRKPRNDVGNQVSPLPELVAEPTGARSMSFVGTHEYLAPEIIKGEGHGS-AVDWWTFGIFLYELLHGKTPFKGSGNRATLFNVVGQPL
                                       ..|.|| .|.|||..   |.|  ..||| .|. |||.| |..||    . ...|...|   
---------------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG---

KFPETSHVSFAARDLIRGLLVKDPQHRLASKRGAT---EIKQHPFF
        |  |.|.||..|.|||..|.      .   .||.||.|
--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RSK-p2_a-2.AA RSK 144-476 30 2.5e-88 299.76 In-house 1-278 (278) Show / Hide 
Range on Protein: 144-476
Range on HMM: 1-278/278
Sequence Identity: 30% (108 aa)

LKRLGCGDIGSVYLAELR---STSCHFAMKVMDKASLASRKK-LLRAQTEKEILQSLD-HPFLPTLYTHFETDKFSCLVMEFCMGGDLHTLRQRQPGKH-
|| || |. |.|.|        |  ..|||| .|| .. |.| . .. || .||.    |||. ||.  |.|..   |.||.|.||.| |  |..  || 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKE--KHF

--FTEQAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVRE---DGHIMLSDFDLSLRCVVSPTLVKSSMDGDKRGPAYCIQPACVQPSCIQPACVVQPS
  |.|  |.||..|. | .|.|| .|...|||||||.|  .   .|||.|.||...                                            
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-----------------------------------------

CLLPRFLSKAKSKKSRKPRNDVGNQVSPLPELVAEPT-GARSMSFVGTHEYLAPEIIK----GEGHGSAVDWWTFGIFLYELLHGKTPFKG---SGNRAT
                                   .  . . |.|..|.||.|||..|    ..||. |.|||..|. .||.| |..||.|   .    .
----------------------------------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEI

LFNVVGQP--LKFPETSHVSFAARDLIRGLLVKDPQHRLAS-KRGATEIKQHPFF
. ..      |..|. . .| .|.||||..| .||. || . ...| ||||||.|
MKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase RSK-p2_a-2.AA RSK-Unclassified 141-288 43 4.3e-61 190.42 In-house 1-148 (283) Show / Hide 
Range on Protein: 141-288
Range on HMM: 1-148/283
Sequence Identity: 43% (65 aa)

FRLLKRLGCGDIGSVYLAELRSTSCHFAMKVMDKASLASRKKLLRAQTEKEILQSLDHPFLPTLYTHFETDKFSCLVMEFCMGGDLHTLRQRQPGKHFTE
|   . .| ||.| ||| . . |   .||||. |  .  ..|  .. ||..|.   .|||  |||  | |     |.||.|||||.    |    | |.|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

QAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVREDGHIMLSDFDLS
  ..|||||| . ||||| ....||||||.|..   .||.||.|||||
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLS
Kinase RSK-p2_a-2.AA RSK-Unclassified 370-476 50 3.2e-52 162.05 In-house 176-283 (283) Show / Hide 
Range on Protein: 370-476
Range on HMM: 176-283/283
Sequence Identity: 50% (54 aa)

GARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLHGKTPFKGSGNRATLFNVVGQPLKFPETSHVSFAARDLIRGLLVKDPQHRLASKRG-AT
| |  ||.|| ||||||.|.. ||. |||||| || .||.| | .|..|     |  |.  ...|||. | .|  .||||. || . |  || .|.| | 
GFRTNSFCGTEEYLAPEMIRRCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDAD

EIKQHPFF
.||.||||
DIKRHPFF
Kinase RSK-p2_a-2.AA SGK 375-476 48 5.7e-46 139.66 In-house 184-283 (283) Show / Hide 
Range on Protein: 375-476
Range on HMM: 184-283/283
Sequence Identity: 48% (50 aa)

SFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLHGKTPFKGSGNRATLF-NVVGQPLKFPETSHVSFAARDLIRGLLVKDPQHRLASKRGATEIKQH
.| || ||||||......|. .||||  |..|||...|. ||  | |..... |   |||..|    .| .|.||| ||| |||. || .||.. |||.|
TFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFY-SRNKQQMYDNIINQPLQIPP--QMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNH

PFF
|||
PFF
Kinase RSK-p2_a-2.AA Akt 374-476 46 2.7e-45 142.68 In-house 160-264 (264) Show / Hide 
Range on Protein: 374-476
Range on HMM: 160-264/264
Sequence Identity: 46% (49 aa)

MSFVGTHEYLAPEIIKGEGHGSAVDWWT-FGIFLYELLHGKTPFKGSGNRATLF-NVVGQPLKFPETSHVSFAARDLIRGLLVKDPQHRLA-SKRGATEI
..| || |||||||..| ||. |||||. .|...||...|  ||    .. ..| .   ||.|||... .| ...|||.||| ||| .||   . .| ||
KTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYN-QDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEI

KQHPFF
|.||.|
KRHPWF
Kinase RSK-p2_a-2.AA RSK 141-288 34 1.6e-42 147.63 In-house 1-152 (271) Show / Hide 
Range on Protein: 141-288
Range on HMM: 1-152/271
Sequence Identity: 34% (54 aa)

FRLLKRLGCGDIGSVYLAELR---STSCHFAMKVMDKASLASRKKLLRAQTEKEILQSLDHPFLPTLYTHFETDKFSCLVMEFCMGGDLHTLRQRQPGKH
. |.. .| |  . ||.        |  |.|||. .||... . .  .. .|  ||   .|||  .|.  |.. .   ..|.|. |||| .  ..|  | 
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQ--KM

FTEQAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVRED----GHIMLSDFDLS
|.|. .|||..|..|..|||| .|.|.|||||||.|. ..    ||| . || ..
FSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFA
Kinase RSK-p2_a-2.AA PKA 141-285 36 4.9e-42 145.96 In-house 1-145 (263) Show / Hide 
Range on Protein: 141-285
Range on HMM: 1-145/263
Sequence Identity: 36% (54 aa)

FRLLKRLGCGDIGSVYLAELRSTSCHFAMKVMDKASLASRKKLLRAQTEKEILQSLDHPFLPT-LYTHFETDKFSCLVMEFCMGGDLHTLRQRQPGKHFT
| ... || |  | |.|.  ... ...|||...|.    .|   .  .|| |||...|||. . .| .| .|..  .|||.. ||.. .  ..   ..|.
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKS--GRFS

EQAAKFYAS-EVLLSLEYLHMLGVVYRDLKPENVLVREDGHIMLSDF
.. |||||  .. | ||||| .  .|||||||| |  ..||| . ||
NPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDF
Kinase RSK-p2_a-2.AA Akt 141-285 40 2.5e-41 129.84 In-house 1-145 (264) Show / Hide 
Range on Protein: 141-285
Range on HMM: 1-145/264
Sequence Identity: 40% (60 aa)

FRLLKRLGCGDIGSVYLAELRSTSCHF-AMKVMDKASLASRKKLLRAQTEKEILQSLDHPFLPTLYTHFETDKFSCLVMEFCMGGDLHTLRQRQPGKHFT
|..|| || |  | |.|..  .|   . ||||  |  .  ....  ..||. |||  .|||.  |.  | | .  ..||..| ||.| .. ||..   |.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRR--FS

EQAAKFYASEVLLSLEYLHMLGVVYRD-LKPENVLVREDGHIMLSDF
|. |.||..|. | .|.||  ...||| |||||.|. .|||| | ||
EDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDF
Kinase RSK-p2_a-2.AA Pkinase 141-288 32 5.8e-41 145.93 Pfam 1-159 (293) Show / Hide 
Range on Protein: 141-288
Range on HMM: 1-159/293
Sequence Identity: 32% (54 aa)

FRLLKRLGCGDIGSVYLAELRSTSCHFAMKVMDKASLAS--RKKLLRAQTEKEILQSLDHPFLPTLYTHFETDKFSCLVMEFCMGG----DLH----TLR
.......| |  |.||..  ..|.. .|.|...| .  |  .. ..|. .| .|...|.||.  .||  ||...  ..|||.|.||    ||.    |  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--

QRQPGKHF--TEQAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVREDGHI----MLSDFDLS
  . .. |  .|. .|||. ..|  |||.|  |...|||||||.|. ..|||     ..|| |.
--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA
Kinase RSK-p2_a-2.AA AGC-Unique 141-288 36 1.2e-40 141.42 In-house 1-149 (270) Show / Hide 
Range on Protein: 141-288
Range on HMM: 1-149/270
Sequence Identity: 36% (55 aa)

FRLLKRLGCGDIGSVYLAELR---STSCHFAMKVMDKASLASRKKLLRAQTEKEILQSLDHPFLPTLYTHFETDKFSCLVMEFCMGGDLHTLRQRQPGKH
| .|| .| |  | ||.   .    |   .|||||.|  .  .| .    ||. ||  ..|||.  .   | . ..  ..|..  |||. .  |.     
FEILKHIGVGSYGRVYAVRRKNGCDTEKFYAMKVMNKRDMSKHKQMVHHNTEWMILTTMHHPFFMRMHYSFQNKDHLFMCMDYVPGGDMFHHMQN--AEC

FTEQAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVREDGHIMLSDFDLS
| |  |.||  ||  |. |||   ...|| ||||.|. .|||||. |. ||
FIEESAHFYICEVICSIHYLHENHIIHRDIKPENILIDNDGHIMITDYGLS
Kinase RSK-p2_a-2.AA SGK 141-288 33 1.7e-40 122.47 In-house 1-172 (283) Show / Hide 
Range on Protein: 141-288
Range on HMM: 1-172/283
Sequence Identity: 33% (58 aa)

FRLLKRLGCGDIGSVYLAELRST------------------SCHFAMKVMDKASLA-------SRKKLLRAQTEK-EILQSLDHPFLPTLYTHFETDKFS
|..|| .| |  | ||...  ..                     .||||  |..          .|.    ..|.  ||. . |||.  |   | |..  
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

CLVMEFCMGGDLHTLRQRQPGKHFTEQAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVREDGHIMLSDFDLS
 .||..  ||..    ||   ||| |  |.|||.|. . ||||| . ..||||||||.|   .||. | || |.
YFVMDYVNGGEMFYHLQRE--KHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLC
Kinase RSK-p2_a-2.AA Ciliate-E2 141-288 26 4.7e-38 128.21 In-house 1-203 (365) Show / Hide 
Range on Protein: 141-288
Range on HMM: 1-203/365
Sequence Identity: 26% (55 aa)

FRLLKRLGCGDIGSVYLAELRSTSCHFA-----------------------MKVMDKASLASRKKLLRAQ----------TEKEILQSLDHPFLPTLYTH
. ..| .| |  ||||... ... . ||                       ||.| |  . . |. ..             ||.||..|.||..  .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--TDKFSCLVMEFCMGGDLHT-LRQR----------------QPGKHFTEQAAK-------FYASEVLLSLEYLHMLG-VVYRDLKPENVLVREDGHI
|.  .|.   ||||.| ||||   ....                .  |....| ..       ||. ...| |||||  . ...||.||||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

MLSDFDLS
 ..|| ||
KIIDFGLS
Kinase RSK-p2_a-2.AA Pkinase 367-476 29 6.4e-31 110.41 Pfam 164-293 (293) Show / Hide 
Range on Protein: 367-476
Range on HMM: 164-293/293
Sequence Identity: 29% (40 aa)

EPTGARSMSFVGTHEYLAPEIIK-GEGHGSAVDWWTFGIFLYELLHGKTPFKGS------GNRATLFNVVGQPLKFPETSHVS-----------------
.  .   ..|.|| .|.|||.|. |...|..||.| .|. |||.| |..||.|.        .. .... | ||.|..    |                 
Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHN

--FAARDLIRGLLVKDPQHRLASKRGATEIKQHPFF
   ...|.|...| |||. |.     |..|.|||.|
WSEECKDFIKWCLCKDPKKRPT----AEQILQHPWF
Kinase RSK-p2_a-2.AA PKA 378-476 40 9.2e-31 108.53 In-house 160-263 (263) Show / Hide 
Range on Protein: 378-476
Range on HMM: 160-263/263
Sequence Identity: 40% (43 aa)

GTHEYLAPEIIKGE-GHGSAVDWWTFGIFLYELLHGKTPFKGS--GNRATLFNVVGQPLKFPETSHVSFAA---RDLIRGLLVKDPQHRL-ASKRGATEI
|| ||||||||... ||| .||||..||  ||.| |..||  .     ..    .   .|||  .|.. .|   .|||. ||..|.  |.   | |.  |
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFP--RHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDI

KQHPFF
| |..|
KNHKWF
Kinase RSK-p2_a-2.AA Ciliate-E2 375-476 26 1.1e-30 102.57 In-house 246-365 (365) Show / Hide 
Range on Protein: 375-476
Range on HMM: 246-365/365
Sequence Identity: 26% (35 aa)

SFVGTHEYLAPEIIKGEG---------HGSAVDWWTFGIFLYELLHGKTPFKGSGNRATLFNVVGQPLKFP----------------ETSHVSFAARDLI
...|| .|.||||..|..         .. ..|.| .|. |||.| ||.||        . .   ....||                .. ..|  . |||
TICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLI

RG----LLVKDPQHRLASKRGATEIKQHPFF
.     .|.|||. |.    |. .|..||.|
KKFGKRMLQKDPEKRIT---GWEQILNHPWF
Kinase RSK-p2_a-2.AA RSK 374-476 37 1.5e-28 99.14 In-house 163-271 (271) Show / Hide 
Range on Protein: 374-476
Range on HMM: 163-271/271
Sequence Identity: 37% (41 aa)

MSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLHGKTPFKGSGNRATLFNVVGQPLKF-----PETSHVSFAARDLIRGLLVKDPQHRLAS-KRGA
|.| .| .|.|||..|  ||. |.||| ||. .|| |.| ||| .  .  .  . . ..|       .  . .|  | ||.|..|  ||. || .   |.
MTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGV

TEIKQHPFF
 .|||||.|
EQIKQHPWF
Kinase RSK-p2_a-2.AA AGC-Unique 376-476 33 3.2e-27 94.2 In-house 171-270 (270) Show / Hide 
Range on Protein: 376-476
Range on HMM: 171-270/270
Sequence Identity: 33% (34 aa)

FVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLHGKTPFKGSGNRATLFNVVGQPLKFPETSHVSFAARDLIRGLLVKDPQHRLA-SKRGATEIKQHP
|.|| .|.||||. . .|| . |||  || ..... .. || .|  .      .   .  |     |  ..|..  |.|.||  ||  |  |  ||| |.
FCGTRHYMAPEIHTEKKHGKSCDWWSVGITYCDMRTDRSPFDASNRNDMYDSMIQKRPRMPMF--LSPDEQDFVNKLIVRDPNQRLGNSPQGFEEIKSHD

FF
.|
MF
Kinase RSK-p2_a-2.AA TyrKc 141-470 15 4.8e-09 -76.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 141-470
Range on HMM: 1-280/280
Sequence Identity: 15% (57 aa)

FRLLKRLGCGDIGSVYLAELRSTSCHFAMKVMDKASLASRKKLLRAQTEKEILQSL--DHPFLPTLYTHFETD-------KFSCLVMEFCMGGDLHTLRQ
 .|.| ||.|  | ||.....      | |.. . .   |. ..|   | .|. .|  .|| .  ||    ..       .  ..|||.. .|||.   .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMR---EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RQPGKHFTEQAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVREDGHIMLSDFDLSLRCVVSPTLVKSSMDGDKRGPAYCIQPACVQPSCIQPACVVQP
.  .| .. .    ..  .    ||||  ... |||   |.|| |..                                                     
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------------------------------------------------

SCLLPRFLSKAKSKKSRKPRNDVGNQVSPLPELV-------AEPTGAR-------SMSFV----GTHE-----YLAPEIIKGEGHGSAVDWWTFGIFLYE
                                 |       .   .         ..  .    |..       .||| |.     .. | | ||. ..|
--------------------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWE

LL-HGKTPFKG------SGNRATLFNVVGQPLKFPET--------SHVSFAARDLIRGLLVKDPQHRLASKRGATEI
..  |..|  |      |  ..  .   |  .. |.          .       ...     ||  |   .    ..
IFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ--IMKQCWHEDPEDRPTFSEIHECF
Kinase RSK-p2_a-2.AA Pkinase_Tyr 141-228 26 2.6e-05 18.62 Pfam 1-96 (270) Show / Hide 
Range on Protein: 141-228
Range on HMM: 1-96/270
Sequence Identity: 26% (26 aa)

FRLLKRLGCGDIGSVYLAELR----STSCHFAMKVM-DKASLAS--RKKLLRAQTEKEILQSL-DHPFLPTLYTHFE-TDKF--SCLVMEFCMGGDLHT
 ...| || |  |.||.....    .| .. | |.. ..|.     |....|   | .|. .| .|| .  ||      ..    ..|||.. .|||..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR---EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD
Kinase RSK-p2_a-2.AA Pkinase_Tyr 400-418 33 1.095207 2.95 Pfam 198-218 (270) Show / Hide 
Range on Protein: 400-418
Range on HMM: 198-218/270
Sequence Identity: 33% (7 aa)

WTFGIFLYELLH-GKTP-FKG
| ||. ..|..  |..| ..|
WSFGVLMWEIFTYGEQPTYPG