Gene RSK-p2_a-1 (S.moellendorffii)

RSK-p2_a-1

Species: S.moellendorffii
Alias: RSK-p2_a-1
External Links:
Annotation:

Classification

Group: AGC
Family: RSK
Subfamily: RSK-p2

Sequence

Name Sequence Type Origin Length Description Download
RSK-p2_a-1.AA Protein None 559 None Fasta, JSON
RSK-p2_a-1.NA RNA None 1680 None Fasta, JSON
RSK-p2_a-1.kin_dom Protein Kinase Domain None 336 None Fasta, JSON

Protein domain

Protein domains of RSK-p2_a-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RSK-p2_a-1.AA AGC 142-477 24 4.6e-138 359.33 In-house 1-395 (395) Show / Hide 
Range on Protein: 142-477
Range on HMM: 1-395/395
Sequence Identity: 24% (113 aa)

FRLLKRLGCGDIGSVYLAELR------STSCHFAMKVMDKAS---LASRKKLLRAQTE------------KEILQSLD----------HPFLPT-LYTHF
|..|| .| |  | |||.. .      .|   .||||..|.    .  .... ...||            ..||. ..          |||.   |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETDKF--SCLVMEFCM---------GG-DLHTLRQRQ-PGKHFTEQAAKFYASE-------VLLSLEYLHM-LGVVYRD-LKPENVLVREDGHIMLSDFD
....    ..|||..          || .|..  | .   ..|.|..|.|||.|       ..| |||||  .|...|| |||||.|  |||||.|.|| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSLRCVVSP---------------------TLVKSSMDGDKRGPAYCIQPACVQPSCIQPACVVQPSCLLPRFLSKAKSKKSRKPRNDVGNQVSPLPELV
|. . . ..                     .    .|| . .                                                  .   |.  
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKS----NMD-T-N--------------------------------------------------K-CNPNNW

AEPT-----------GARSMSFVG--THEYLAPEIIKGEGHGSAVDWWT--FGIFLYELLHGKTPFKGSG---------NRATLFNVVG-------QPLK
 .             ..|  .|.|  |.||.||||.    .| |.|||.  .|...||.| |..|| |           |.. .|. .        ...|
QRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVK

FPET--------SHVSFAARDLIRGLLVKDPQHRLASKR------GATEIKQHPFF
||          ...|  |.|||..||.||| .|| ...      || |||.||.|
FPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase RSK-p2_a-1.AA AktR 142-477 30 6.7e-93 314.93 In-house 1-268 (268) Show / Hide 
Range on Protein: 142-477
Range on HMM: 1-268/268
Sequence Identity: 30% (105 aa)

FRLLKRLGCGDIGSVYLAELR-STSCHFAMKVMDKASLASRKKLLRAQTEKEILQ-SLDHPFLPTLYTHFETDKFSCLVMEFCMGGDLHTLRQRQPGKHF
|...| || |  | |||.. .  .   .|||. .|  .  |..  ...||. |..   .|||.  |.  |.|.. . ..||.| ||.| .  ...  |.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKK--KKF

TEQAAKFYASEVLLSLEYLHML-GVVYRDLKPENVLVREDGHIMLSDFDLSLRCVVSPTLVKSSMDGDKRGPAYCIQPACVQPSCIQPACVVQPSCLLPR
.|. |.||....|| |||||    ..|||||||| |  ||||. ..|| ||                                                 
SEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK------------------------------------------------

FLSKAKSKKSRKPRNDVGNQVSPLPELVAEPTGARSMSFVGTHEYLAPEIIKG-EGHGSAVDWWTFGIFLYELLHGKTPFKGSGNRATLFNVVGQP-LKF
                          .. .    .  ||.||.||.|||.|.  .||. .||||.||||.||.. | .||  . ..  ...   .. .||
-------------------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKF

PETSHVSFAARDLIR-GLLVKDPQHRLA-SKRGATEIKQHPFF
|..| .|....|||  .|| |.|..||  .. |..||| ||.|
PYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase RSK-p2_a-1.AA S_TKc 142-477 24 1.4e-88 301.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 142-477
Range on HMM: 1-231/231
Sequence Identity: 24% (86 aa)

FRLLKRLGCGDIGSVYLAELRSTSCHFAMKVMDKASLASRKKLLRAQTEKEILQSLDHPFLPTLYTHFETDKFSCLVMEFCMG--GDLHTLRQRQPGKH-
...|. .| |  |.||..  ..|  ..|.|...           ... | .||.. .||.. .|| .|.. .. ..|||.| |  |||... ......  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTEQAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVREDGHIMLSDFDLSLRCVVSPTLVKSSMDGDKRGPAYCIQPACVQPSCIQPACVVQPSCL
   |.|  |.||. .... |||.| .|...|||||||.|. |  ||...|| |. .                                            
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------

LPRFLSKAKSKKSRKPRNDVGNQVSPLPELVAEPTGARSMSFVGTHEYLAPEIIKGEGHGS-AVDWWTFGIFLYELLHGKTPFKGSGNRATLFNVVGQPL
                                       ..|.|| .|.|||..   |.|  ..||| .|. |||.| |..||    . ...|...|   
---------------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG---

KFPETSHVSFAARDLIRGLLVKDPQHRLASKRGAT---EIKQHPFF
        |  |.|.||..|.|||..|.      .   .||.||.|
--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RSK-p2_a-1.AA RSK 145-477 30 2.5e-88 299.76 In-house 1-278 (278) Show / Hide 
Range on Protein: 145-477
Range on HMM: 1-278/278
Sequence Identity: 30% (108 aa)

LKRLGCGDIGSVYLAELR---STSCHFAMKVMDKASLASRKK-LLRAQTEKEILQSLD-HPFLPTLYTHFETDKFSCLVMEFCMGGDLHTLRQRQPGKH-
|| || |. |.|.|        |  ..|||| .|| .. |.| . .. || .||.    |||. ||.  |.|..   |.||.|.||.| |  |..  || 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKE--KHF

--FTEQAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVRE---DGHIMLSDFDLSLRCVVSPTLVKSSMDGDKRGPAYCIQPACVQPSCIQPACVVQPS
  |.|  |.||..|. | .|.|| .|...|||||||.|  .   .|||.|.||...                                            
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-----------------------------------------

CLLPRFLSKAKSKKSRKPRNDVGNQVSPLPELVAEPT-GARSMSFVGTHEYLAPEIIK----GEGHGSAVDWWTFGIFLYELLHGKTPFKG---SGNRAT
                                   .  . . |.|..|.||.|||..|    ..||. |.|||..|. .||.| |..||.|   .    .
----------------------------------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEI

LFNVVGQP--LKFPETSHVSFAARDLIRGLLVKDPQHRLAS-KRGATEIKQHPFF
. ..      |..|. . .| .|.||||..| .||. || . ...| ||||||.|
MKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase RSK-p2_a-1.AA RSK-Unclassified 142-289 43 4.3e-61 190.42 In-house 1-148 (283) Show / Hide 
Range on Protein: 142-289
Range on HMM: 1-148/283
Sequence Identity: 43% (65 aa)

FRLLKRLGCGDIGSVYLAELRSTSCHFAMKVMDKASLASRKKLLRAQTEKEILQSLDHPFLPTLYTHFETDKFSCLVMEFCMGGDLHTLRQRQPGKHFTE
|   . .| ||.| ||| . . |   .||||. |  .  ..|  .. ||..|.   .|||  |||  | |     |.||.|||||.    |    | |.|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

QAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVREDGHIMLSDFDLS
  ..|||||| . ||||| ....||||||.|..   .||.||.|||||
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLS
Kinase RSK-p2_a-1.AA RSK-Unclassified 371-477 50 3.2e-52 162.05 In-house 176-283 (283) Show / Hide 
Range on Protein: 371-477
Range on HMM: 176-283/283
Sequence Identity: 50% (54 aa)

GARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLHGKTPFKGSGNRATLFNVVGQPLKFPETSHVSFAARDLIRGLLVKDPQHRLASKRG-AT
| |  ||.|| ||||||.|.. ||. |||||| || .||.| | .|..|     |  |.  ...|||. | .|  .||||. || . |  || .|.| | 
GFRTNSFCGTEEYLAPEMIRRCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDAD

EIKQHPFF
.||.||||
DIKRHPFF
Kinase RSK-p2_a-1.AA SGK 376-477 48 5.7e-46 139.66 In-house 184-283 (283) Show / Hide 
Range on Protein: 376-477
Range on HMM: 184-283/283
Sequence Identity: 48% (50 aa)

SFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLHGKTPFKGSGNRATLF-NVVGQPLKFPETSHVSFAARDLIRGLLVKDPQHRLASKRGATEIKQH
.| || ||||||......|. .||||  |..|||...|. ||  | |..... |   |||..|    .| .|.||| ||| |||. || .||.. |||.|
TFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFY-SRNKQQMYDNIINQPLQIPP--QMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNH

PFF
|||
PFF
Kinase RSK-p2_a-1.AA Akt 375-477 46 2.7e-45 142.68 In-house 160-264 (264) Show / Hide 
Range on Protein: 375-477
Range on HMM: 160-264/264
Sequence Identity: 46% (49 aa)

MSFVGTHEYLAPEIIKGEGHGSAVDWWT-FGIFLYELLHGKTPFKGSGNRATLF-NVVGQPLKFPETSHVSFAARDLIRGLLVKDPQHRLA-SKRGATEI
..| || |||||||..| ||. |||||. .|...||...|  ||    .. ..| .   ||.|||... .| ...|||.||| ||| .||   . .| ||
KTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYN-QDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEI

KQHPFF
|.||.|
KRHPWF
Kinase RSK-p2_a-1.AA RSK 142-289 34 1.6e-42 147.63 In-house 1-152 (271) Show / Hide 
Range on Protein: 142-289
Range on HMM: 1-152/271
Sequence Identity: 34% (54 aa)

FRLLKRLGCGDIGSVYLAELR---STSCHFAMKVMDKASLASRKKLLRAQTEKEILQSLDHPFLPTLYTHFETDKFSCLVMEFCMGGDLHTLRQRQPGKH
. |.. .| |  . ||.        |  |.|||. .||... . .  .. .|  ||   .|||  .|.  |.. .   ..|.|. |||| .  ..|  | 
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQ--KM

FTEQAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVRED----GHIMLSDFDLS
|.|. .|||..|..|..|||| .|.|.|||||||.|. ..    ||| . || ..
FSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFA
Kinase RSK-p2_a-1.AA PKA 142-286 36 4.9e-42 145.96 In-house 1-145 (263) Show / Hide 
Range on Protein: 142-286
Range on HMM: 1-145/263
Sequence Identity: 36% (54 aa)

FRLLKRLGCGDIGSVYLAELRSTSCHFAMKVMDKASLASRKKLLRAQTEKEILQSLDHPFLPT-LYTHFETDKFSCLVMEFCMGGDLHTLRQRQPGKHFT
| ... || |  | |.|.  ... ...|||...|.    .|   .  .|| |||...|||. . .| .| .|..  .|||.. ||.. .  ..   ..|.
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKS--GRFS

EQAAKFYAS-EVLLSLEYLHMLGVVYRDLKPENVLVREDGHIMLSDF
.. |||||  .. | ||||| .  .|||||||| |  ..||| . ||
NPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDF
Kinase RSK-p2_a-1.AA Akt 142-286 40 2.5e-41 129.84 In-house 1-145 (264) Show / Hide 
Range on Protein: 142-286
Range on HMM: 1-145/264
Sequence Identity: 40% (60 aa)

FRLLKRLGCGDIGSVYLAELRSTSCHF-AMKVMDKASLASRKKLLRAQTEKEILQSLDHPFLPTLYTHFETDKFSCLVMEFCMGGDLHTLRQRQPGKHFT
|..|| || |  | |.|..  .|   . ||||  |  .  ....  ..||. |||  .|||.  |.  | | .  ..||..| ||.| .. ||..   |.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRR--FS

EQAAKFYASEVLLSLEYLHMLGVVYRD-LKPENVLVREDGHIMLSDF
|. |.||..|. | .|.||  ...||| |||||.|. .|||| | ||
EDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDF
Kinase RSK-p2_a-1.AA Pkinase 142-289 32 5.8e-41 145.93 Pfam 1-159 (293) Show / Hide 
Range on Protein: 142-289
Range on HMM: 1-159/293
Sequence Identity: 32% (54 aa)

FRLLKRLGCGDIGSVYLAELRSTSCHFAMKVMDKASLAS--RKKLLRAQTEKEILQSLDHPFLPTLYTHFETDKFSCLVMEFCMGG----DLH----TLR
.......| |  |.||..  ..|.. .|.|...| .  |  .. ..|. .| .|...|.||.  .||  ||...  ..|||.|.||    ||.    |  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--

QRQPGKHF--TEQAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVREDGHI----MLSDFDLS
  . .. |  .|. .|||. ..|  |||.|  |...|||||||.|. ..|||     ..|| |.
--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA
Kinase RSK-p2_a-1.AA AGC-Unique 142-289 36 1.2e-40 141.42 In-house 1-149 (270) Show / Hide 
Range on Protein: 142-289
Range on HMM: 1-149/270
Sequence Identity: 36% (55 aa)

FRLLKRLGCGDIGSVYLAELR---STSCHFAMKVMDKASLASRKKLLRAQTEKEILQSLDHPFLPTLYTHFETDKFSCLVMEFCMGGDLHTLRQRQPGKH
| .|| .| |  | ||.   .    |   .|||||.|  .  .| .    ||. ||  ..|||.  .   | . ..  ..|..  |||. .  |.     
FEILKHIGVGSYGRVYAVRRKNGCDTEKFYAMKVMNKRDMSKHKQMVHHNTEWMILTTMHHPFFMRMHYSFQNKDHLFMCMDYVPGGDMFHHMQN--AEC

FTEQAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVREDGHIMLSDFDLS
| |  |.||  ||  |. |||   ...|| ||||.|. .|||||. |. ||
FIEESAHFYICEVICSIHYLHENHIIHRDIKPENILIDNDGHIMITDYGLS
Kinase RSK-p2_a-1.AA SGK 142-289 33 1.7e-40 122.47 In-house 1-172 (283) Show / Hide 
Range on Protein: 142-289
Range on HMM: 1-172/283
Sequence Identity: 33% (58 aa)

FRLLKRLGCGDIGSVYLAELRST------------------SCHFAMKVMDKASLA-------SRKKLLRAQTEK-EILQSLDHPFLPTLYTHFETDKFS
|..|| .| |  | ||...  ..                     .||||  |..          .|.    ..|.  ||. . |||.  |   | |..  
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

CLVMEFCMGGDLHTLRQRQPGKHFTEQAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVREDGHIMLSDFDLS
 .||..  ||..    ||   ||| |  |.|||.|. . ||||| . ..||||||||.|   .||. | || |.
YFVMDYVNGGEMFYHLQRE--KHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLC
Kinase RSK-p2_a-1.AA Ciliate-E2 142-289 26 4.7e-38 128.21 In-house 1-203 (365) Show / Hide 
Range on Protein: 142-289
Range on HMM: 1-203/365
Sequence Identity: 26% (55 aa)

FRLLKRLGCGDIGSVYLAELRSTSCHFA-----------------------MKVMDKASLASRKKLLRAQ----------TEKEILQSLDHPFLPTLYTH
. ..| .| |  ||||... ... . ||                       ||.| |  . . |. ..             ||.||..|.||..  .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--TDKFSCLVMEFCMGGDLHT-LRQR----------------QPGKHFTEQAAK-------FYASEVLLSLEYLHMLG-VVYRDLKPENVLVREDGHI
|.  .|.   ||||.| ||||   ....                .  |....| ..       ||. ...| |||||  . ...||.||||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

MLSDFDLS
 ..|| ||
KIIDFGLS
Kinase RSK-p2_a-1.AA Pkinase 368-477 29 6.4e-31 110.41 Pfam 164-293 (293) Show / Hide 
Range on Protein: 368-477
Range on HMM: 164-293/293
Sequence Identity: 29% (40 aa)

EPTGARSMSFVGTHEYLAPEIIK-GEGHGSAVDWWTFGIFLYELLHGKTPFKGS------GNRATLFNVVGQPLKFPETSHVS-----------------
.  .   ..|.|| .|.|||.|. |...|..||.| .|. |||.| |..||.|.        .. .... | ||.|..    |                 
Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHN

--FAARDLIRGLLVKDPQHRLASKRGATEIKQHPFF
   ...|.|...| |||. |.     |..|.|||.|
WSEECKDFIKWCLCKDPKKRPT----AEQILQHPWF
Kinase RSK-p2_a-1.AA PKA 379-477 40 9.2e-31 108.53 In-house 160-263 (263) Show / Hide 
Range on Protein: 379-477
Range on HMM: 160-263/263
Sequence Identity: 40% (43 aa)

GTHEYLAPEIIKGE-GHGSAVDWWTFGIFLYELLHGKTPFKGS--GNRATLFNVVGQPLKFPETSHVSFAA---RDLIRGLLVKDPQHRL-ASKRGATEI
|| ||||||||... ||| .||||..||  ||.| |..||  .     ..    .   .|||  .|.. .|   .|||. ||..|.  |.   | |.  |
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFP--RHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDI

KQHPFF
| |..|
KNHKWF
Kinase RSK-p2_a-1.AA Ciliate-E2 376-477 26 1.1e-30 102.57 In-house 246-365 (365) Show / Hide 
Range on Protein: 376-477
Range on HMM: 246-365/365
Sequence Identity: 26% (35 aa)

SFVGTHEYLAPEIIKGEG---------HGSAVDWWTFGIFLYELLHGKTPFKGSGNRATLFNVVGQPLKFP----------------ETSHVSFAARDLI
...|| .|.||||..|..         .. ..|.| .|. |||.| ||.||        . .   ....||                .. ..|  . |||
TICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLI

RG----LLVKDPQHRLASKRGATEIKQHPFF
.     .|.|||. |.    |. .|..||.|
KKFGKRMLQKDPEKRIT---GWEQILNHPWF
Kinase RSK-p2_a-1.AA RSK 375-477 37 1.5e-28 99.14 In-house 163-271 (271) Show / Hide 
Range on Protein: 375-477
Range on HMM: 163-271/271
Sequence Identity: 37% (41 aa)

MSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLHGKTPFKGSGNRATLFNVVGQPLKF-----PETSHVSFAARDLIRGLLVKDPQHRLAS-KRGA
|.| .| .|.|||..|  ||. |.||| ||. .|| |.| ||| .  .  .  . . ..|       .  . .|  | ||.|..|  ||. || .   |.
MTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGV

TEIKQHPFF
 .|||||.|
EQIKQHPWF
Kinase RSK-p2_a-1.AA AGC-Unique 377-477 33 3.2e-27 94.2 In-house 171-270 (270) Show / Hide 
Range on Protein: 377-477
Range on HMM: 171-270/270
Sequence Identity: 33% (34 aa)

FVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLHGKTPFKGSGNRATLFNVVGQPLKFPETSHVSFAARDLIRGLLVKDPQHRLA-SKRGATEIKQHP
|.|| .|.||||. . .|| . |||  || ..... .. || .|  .      .   .  |     |  ..|..  |.|.||  ||  |  |  ||| |.
FCGTRHYMAPEIHTEKKHGKSCDWWSVGITYCDMRTDRSPFDASNRNDMYDSMIQKRPRMPMF--LSPDEQDFVNKLIVRDPNQRLGNSPQGFEEIKSHD

FF
.|
MF
Kinase RSK-p2_a-1.AA TyrKc 142-471 15 4.8e-09 -76.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 142-471
Range on HMM: 1-280/280
Sequence Identity: 15% (57 aa)

FRLLKRLGCGDIGSVYLAELRSTSCHFAMKVMDKASLASRKKLLRAQTEKEILQSL--DHPFLPTLYTHFETD-------KFSCLVMEFCMGGDLHTLRQ
 .|.| ||.|  | ||.....      | |.. . .   |. ..|   | .|. .|  .|| .  ||    ..       .  ..|||.. .|||.   .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMR---EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RQPGKHFTEQAAKFYASEVLLSLEYLHMLGVVYRDLKPENVLVREDGHIMLSDFDLSLRCVVSPTLVKSSMDGDKRGPAYCIQPACVQPSCIQPACVVQP
.  .| .. .    ..  .    ||||  ... |||   |.|| |..                                                     
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------------------------------------------------

SCLLPRFLSKAKSKKSRKPRNDVGNQVSPLPELV-------AEPTGAR-------SMSFV----GTHE-----YLAPEIIKGEGHGSAVDWWTFGIFLYE
                                 |       .   .         ..  .    |..       .||| |.     .. | | ||. ..|
--------------------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWE

LL-HGKTPFKG------SGNRATLFNVVGQPLKFPET--------SHVSFAARDLIRGLLVKDPQHRLASKRGATEI
..  |..|  |      |  ..  .   |  .. |.          .       ...     ||  |   .    ..
IFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ--IMKQCWHEDPEDRPTFSEIHECF
Kinase RSK-p2_a-1.AA Pkinase_Tyr 142-229 26 2.6e-05 18.62 Pfam 1-96 (270) Show / Hide 
Range on Protein: 142-229
Range on HMM: 1-96/270
Sequence Identity: 26% (26 aa)

FRLLKRLGCGDIGSVYLAELR----STSCHFAMKVM-DKASLAS--RKKLLRAQTEKEILQSL-DHPFLPTLYTHFE-TDKF--SCLVMEFCMGGDLHT
 ...| || |  |.||.....    .| .. | |.. ..|.     |....|   | .|. .| .|| .  ||      ..    ..|||.. .|||..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR---EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD
Kinase RSK-p2_a-1.AA Pkinase_Tyr 401-419 33 1.095207 2.95 Pfam 198-218 (270) Show / Hide 
Range on Protein: 401-419
Range on HMM: 198-218/270
Sequence Identity: 33% (7 aa)

WTFGIFLYELLH-GKTP-FKG
| ||. ..|..  |..| ..|
WSFGVLMWEIFTYGEQPTYPG