Gene NDR1_c (S.moellendorffii)

NDR1_c

Species: S.moellendorffii
Alias: NDR1_c
External Links:
Annotation:

Classification

Group: AGC
Family: NDR
Subfamily: NDR-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
NDR1_c.AA Protein None 524 None Fasta, JSON
NDR1_c.NA RNA None 1575 None Fasta, JSON
NDR1_c.kin_dom Protein Kinase Domain None 316 None Fasta, JSON

Protein domain

Protein domains of NDR1_c.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NDR1_c.AA NDR 120-424 50 5.4e-183 569.9 In-house 1-350 (350) Show / Hide 
Range on Protein: 120-424
Range on HMM: 1-350/350
Sequence Identity: 50% (176 aa)

FELLTIIGRGAFGEVRLCRHKENGEIYAMKKLKKSEMLSRGQVEHVRAERNLLAEVD--THCIVKLHYSFQDAEYLYLIMEYLPGGDMMT---LLMRKDT
|| ..|||.||||||.|.|.|..|.|||||...||||. . || ||||||  .||.|  .  .||| |||||. ||||.|||.|||||||   |||..|.
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LTEDEARFYVAQSVLAIESIHKHNYIHRDIKPDNLLLDKNGHMKLSDFGLCKP-----------LDCN--TLSTLHENEEDEPREPMDIDERLVSPSTGS
.|||.|||| |  |.||||.|| .||||||||||.|.|| || ||.|||||.            ..    | ||.| ..  .  . |.  ..  ....  
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN

SWRSQQEQ------------------LLHWQKNRRMLAFSTVGTPDYIAPEVLLK-KGYGMDCDWWSLGAIMFEMLVGYPPFYSDEPMNTCRKIVNWRTH
|. . |                       |..||| ||.||||||||.||||... .||.. |||||||.||.|||||||||.||.|  ||.|| ||.. 
SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT

L-----KFPQEARLSPEAKDLICRLLC-DVEHRLGSRD--TNEIKAIIYL
.      || || |||||.||| ||.| | .|||||      |||.  . 
WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase NDR1_c.AA AGC 120-424 33 4.90000000001e-172 449.19 In-house 1-395 (395) Show / Hide 
Range on Protein: 120-424
Range on HMM: 1-395/395
Sequence Identity: 33% (140 aa)

FELLTIIGRGAFGEVRLCRHK------ENGEIYAMKKLKKSE--------MLSRGQVEH-------VRAERNLLAEVDTHC----------IVK-LHYSF
||.|..||.|.||.|.|.|.|       .|..||||.|||..        |. . ..||       |..||| |.... ..          ||| |||||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDAEY--LYLIMEYLP---------GG-DMMTLLM---RKDTLTEDEARFYVAQ-------SVLAIESIHK-HNYIHRD-IKPDNLLLDKNGHMKLSDFG
|| ..  ||..|||.|         || .... |.   .. ...|..|||| |.        |||.|..|. ...|||| .||.|.|||..|| ||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKPLDCN-----------TLSTLHENEEDEPREPMDIDERLVSPSTGSSWRSQQEQLLHWQKNR-----------RMLAFSTVG--TPDYIAPEVLLKK
||| .  .           .... |...  .  . || . .            . . . .||.|.           | .. . .|  ||.|.|||.|   
LCKEGMNDGEKGQQSQSNMKFHW-HNKKY-Q-KSNMD-T-N------------K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL---

GYGMDCDWWS--LGAIMFEMLVGYPPFYSDE----------PMNTCRKIV------NWRTHLKFP------QEARLSPEAKDLICRLLC-DVEHRLGSRD
 ||  |||||  ||..|.|||.||||||.|.          || .  ||       ||. .. ||       .  .|||||||| .||| | |.|||...
-YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGG

-------TNEIKAIIYL
       ..|||.  . 
NDFGDKGAEEIKNHPWF
Kinase NDR1_c.AA MAST 120-435 32 8.4e-111 339.84 In-house 1-337 (337) Show / Hide 
Range on Protein: 120-435
Range on HMM: 1-337/337
Sequence Identity: 32% (122 aa)

FELLTIIGRGAFGEVRLCRHKENGEIYAMKKLKKSEMLSRGQVEHVRAERNLLAEVDTHCIVKLHYSFQD--AEYLYLIMEYLPGGDMMTLLMRKD-TLT
|| . .|..||.| | | .||. ....|||..... .. . ||..|..||| |....   .||. ||||    .||...|||. |||  .||     .. 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EDEARFYVAQSVLAIESIHKHNYIHRDIKPDNLLLDKNGHMKLSDFGLCKPLDCNTLSTLHENE--------EDEPREPMDIDERLVSPSTGSSWRSQQE
|..|..|.|. ||..| .|..  .|||.||||.|.|.||| || |||| |  . ....| |..         .                        .. 
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSK-VGFMDKTTNHYEGYFNTNIFGK------------------------NHF

QLLHWQKNRRML-------------------------------------AFSTVGTPDYIAPEVLLKKG-YGMDCDWWSLGAIMFEMLVGYPPFYSDEPM
 . | ||| ...                                       . .||||||||||.|..| ||   ||||.| ||.| |||.|||  |.| 
NEYHIQKNYQQFQQDFGINGNTNKNQIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPE

N-TCRKIVNWRTHLKFPQE------ARLSPEAKDLICRLL-CDVEHRLGSRDTNEIKAIIYLYFFQNLAHPFF
  .  .|.|   .. .| |        .||||.||| .||  .   |||..   |||            ||||
EMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGADEIK-----------QHPFF
Kinase NDR1_c.AA MAST 120-424 35 1.9e-104 337.68 In-house 1-334 (334) Show / Hide 
Range on Protein: 120-424
Range on HMM: 1-334/334
Sequence Identity: 35% (118 aa)

FELLTIIGRGAFGEVRLCRHKENGEIYAMKKLKKSEMLSRGQVEHVRAERNLLAEVDTHCIVKLHYSFQDAEYLYLIMEYLPGGDMMTLLMRKDTLTEDE
||   .|..||.| | | .||. ....|||..|||.|. . .|..|..||| ||...   .||. |||| ..||...|||. |||  .||    .. |. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARFYVAQSVLAIESIHKHNYIHRDIKPDNLLLDKNGHMKLSDFGLCKPLDCNTLSTLHENE----------EDEPREPMDIDERLV----------SPST
|..|.|. ||..| .|.|  .|||.||||.|.|.||| || |||| |  . ..... ...            | .  ..  .....            . 
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSK-VGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQI

GSSWRSQQEQLLHWQKNRRMLAFSTVGTPDYIAPEVLLKKG-YGMDCDWWSLGAIMFEMLVGYPPFYSDEPMNTCRKIVNWR-THLKFPQE------ARL
 .   ..|.|.    ..  .   . .||||||||||.|..| .|.  ||||.| ||.| |||.|||  |.|  .  .|.| .    ..| .        .
QQQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAM

SPEAKDLICRLL-CDVEHRLGSR-DTNEIKAIIYL
||||.||| .|| .| . |||..    |.|   ..
SPEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase NDR1_c.AA DMPK 120-265 53 1.5e-101 251.57 In-house 1-147 (270) Show / Hide 
Range on Protein: 120-265
Range on HMM: 1-147/270
Sequence Identity: 53% (79 aa)

FELLTIIGRGAFGEVRLCRHKENGEIYAMKKLKKSEMLSRGQVEHVRAERNLLAEVDTHCIVKLHYSFQDAEYLYLIMEYLPGGDMMTLLMRKD-TLTED
|| |..||||.|||| . |||. ...||||...| |||.| ..  .. ||. ..  .   |..||| ||| .|||..||| ||||. ||. | .  . ||
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

EARFYVAQSVLAIESIHKHNYIHRDIKPDNLLLDKNGHMKLSDFGLC
 ||||.|  |||| |||.  |.|||||||| |||..|| || ||| |
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSC
Kinase NDR1_c.AA S_TKc 120-424 33 1.3e-99 338.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 120-424
Range on HMM: 1-231/231
Sequence Identity: 33% (107 aa)

FELLTIIGRGAFGEVRLCRHKENGEIYAMKKLKKSEMLSRGQVEHVRAERNLLAEVDTHCIVKLHYSFQDAEYLYLIMEYLPG--GDMMTLLMRKDT---
.|.| .||.||||.|..||||. |.|.|.|..|          ||.| |...| . .   ||||...||| ..||..|||..|  ||..... .. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEDEARFYVAQSVLAIESIHKHNYIHRDIKPDNLLLDKNGHMKLSDFGLCKPLDCNTLSTLHENEEDEPREPMDIDERLVSPSTGSSWRSQQEQLL
   ..| .||||..| ..|.| .|.|. ||||.||.|.|||.  | |..||||.. |                                           
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------

HWQKNRRMLAFSTVGTPDYIAPEVLLKKGYGM-DCDWWSLGAIMFEMLVGYPPFYSDEPMNTCRKIVNWRTHLKFPQEARLSPEAKDLICRLLC-DVEHR
           . .|||.|.|||||   |||   |||||.| |..|||.|||||.  ... . .||.              ||||||.|...|. | |.|
----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKR

LGSRDTNE----IKAIIYL
..  .  .    ||.  ..
PTA-EALQDEWDIKCHPWF
Kinase NDR1_c.AA AktR 120-435 36 1.4e-99 337.15 In-house 1-268 (268) Show / Hide 
Range on Protein: 120-435
Range on HMM: 1-268/268
Sequence Identity: 36% (117 aa)

FELLTIIGRGAFGEVRLCRHK-ENGEIYAMKKLKKSEMLSRGQVEHVRAERNLLA-EVDTHCIVKLHYSFQDAEYLYLIMEYLPGGDMMTLLMRKDTLTE
|... ..|.||||.| |...| .|...|||| .||...  | | .|.. ||| .. ...   ||||||.||. |.|..|||| |||.. . | .| ...|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DEARFYVAQSVLAIESIHKH-NYIHRDIKPDNLLLDKNGHMKLSDFGLCKPLDCNTLSTLHENEEDEPREPMDIDERLVSPSTGSSWRSQQEQLLHWQKN
..|||| || .||.|  |.| | | ||.||.|.|||..|| |..|||| |                                            |  .. 
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK--------------------------------------------LQFMMH

RRMLAFSTVGTPDYIAPEVLLK-KGYGMDCDWWSLGAIMFEMLVGYPPFYSDEPMNTCRKIVNWRTHLKFPQEARLSPEAKDLIC-RLLC-DVEHRLG--
.. .| | .||| |.|||...| ||..  .|||..|.  .||..|.||||..       || . .  .|||. . .|...||||. .||| . ..|||  
YDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYY

SRDTNEIKAIIYLYFFQNLAHPFF
. .. |||            ||.|
CNGWEEIK-----------SHPWF
Kinase NDR1_c.AA RSK 120-424 34 8.3e-97 327.92 In-house 1-278 (278) Show / Hide 
Range on Protein: 120-424
Range on HMM: 1-278/278
Sequence Identity: 34% (111 aa)

FELLTIIGRGAFGEVRLCRHKENGEIYAMKKLKKSEMLSRGQ-VEHVRAERNLLAEVD-THCIVKLHYSFQDAEYLYLIMEYLPGGDMMTLLMRKDT---
 ..|. .| |..  .| |.|. .| ||||| |||...  |   ..|...||| |...     ||.|||.||. ..|||||||..||.. | | .. .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LTEDEARFYVAQSVLAIESIHKHNYIHRDIKPDNLLLDK---NGHMKLSDFGLCKPLDCNTLSTLHENEEDEPREPMDIDERLVSPSTGSSWRSQQEQLL
..||||.|| |. |||.| .|..  ||||.||.| |.|    .|| ||.|||.|| .                                           
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------------------------------------------

HWQKNR-RMLAFSTVGTPDYIAPEVLL----KKGYGMDCDWWSLGAIMFEMLVGYPPFYS---DEPMNTCRKIVNWRTHLKFPQEARLSPEAKDLICRLL
   ...   .. . ..| .|.|||.|     ..|..  |||||||..|.|||.|.|||..   . .  . ..| . .  |..|  . ||.|||||| ..|
---RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKML

C-DVEHRLG--SRDTNEIKAIIYL
. | . |||   .|..|||.  ..
HRDPHKRLGCGPQDAEEIKQHPWF
Kinase NDR1_c.AA Akt 120-266 48 6.2e-72 229.21 In-house 1-149 (264) Show / Hide 
Range on Protein: 120-266
Range on HMM: 1-149/264
Sequence Identity: 48% (72 aa)

FELLTIIGRGAFGEVRLCRHKENGEIY-AMKKLKKSEMLSRGQVEHVRAERNLLAEVDTHCIVKLHYSFQDAEYLYLIMEYLPGGDMMTLLMRKDTLTED
|..| ..|.|.|| | |.. | ....| ||| |||.  . ..||||. .|||.|  ..   ||.||||||....||..|.| .||.  ..| || . .||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

EARFYVAQSVLAIESIHKHNYIHRD-IKPDNLLLDKNGHMKLSDFGLCK
.||||.|. .||||  |..| | ||  || |.|.||.|| .| ||||||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCK
Kinase NDR1_c.AA GEK 120-265 55 1e-65 219.44 In-house 1-147 (269) Show / Hide 
Range on Protein: 120-265
Range on HMM: 1-147/269
Sequence Identity: 55% (81 aa)

FELLTIIGRGAFGEVRLCRHKENGEIYAMKKLKKSEMLSRGQVEHVRAERNLLAEVDTHCIVKLHYSFQDAEYLYLIMEYLPGGDMMTLLMR-KDTLTED
||.| .|||||||||   . |. ...|||| |.| ||| |. .   | ||  | . | . | .||| ||| .||||.|.|  |||..||| . .| | ||
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

EARFYVAQSVLAIESIHKHNYIHRDIKPDNLLLDKNGHMKLSDFGLC
 ||||.|  |.||.|.|. .|.||||||||.|||.|||..| ||| |
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFGSC
Kinase NDR1_c.AA ROCK 120-265 51 2.3e-59 200.79 In-house 1-145 (263) Show / Hide 
Range on Protein: 120-265
Range on HMM: 1-145/263
Sequence Identity: 51% (75 aa)

FELLTIIGRGAFGEVRLCRHKENGEIYAMKKLKKSEMLSRGQVEHVRAERNLLAEVDTHCIVKLHYSFQDAEYLYLIMEYLPGGDMMTLLMRKDTLTEDE
|... .|||||||||.| |||.  ..|||| | | ||. |        ||...|      ||.||| |||. |||..|.|.||||..  || .  . |  
FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVN-LMSNYDVPEKW

ARFYVAQSVLAIESIHKHNYIHRDIKPDNLLLDKNGHMKLSDFGLC
|||| .  |||...||   .||||.||||.|||| ||.|| ||| |
ARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFGTC
Kinase NDR1_c.AA DMPK 325-435 47 2.4e-56 137.27 In-house 162-270 (270) Show / Hide 
Range on Protein: 325-435
Range on HMM: 162-270/270
Sequence Identity: 47% (57 aa)

VGTPDYIAPEVL--LKKG----YGMDCDWWSLGAIMFEMLVGYPPFYSDEPMNTCRKIVNW-RTHLKFPQEAR--LSPEAKDLICRLLCDVEHRLGSRDT
|||||||.||||  .  .    || .|||||.| .|.|||.|  ||| |    |  ||.|  ..||.||..    .|.|||||||.|||| |.|||    
VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGY

NEIKAIIYLYFFQNLAHPFF
 ..|           .||||
EDFK-----------CHPFF
Kinase NDR1_c.AA Pkinase 120-266 35 1.3e-50 179.27 Pfam 1-160 (293) Show / Hide 
Range on Protein: 120-266
Range on HMM: 1-160/293
Sequence Identity: 35% (57 aa)

FELLTIIGRGAFGEVRLCRHKENGEIYAMKKLKKSEMLSRGQVEHVR-AERNLLAEVDTHCIVKLHYSFQDAEYLYLIMEYLPGG----DMMTLLM--RK
.... .||.|.||.|..|.|| .|.|.|.|..||..  |  ...|.| .|  ......  .||.|...|.|  ..|..|||..||    | .....  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DTL--TEDEARFYVAQSVLAIESIHKHNYIHRDIKPDNLLLDKNGHM----KLSDFGLCK
 ..  .|.|..||. | . ..| .|... ||||.||.|.|.|.|||     |..||||.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAK
Kinase NDR1_c.AA ROCK 325-424 49 1.4e-35 118.44 In-house 160-263 (263) Show / Hide 
Range on Protein: 325-424
Range on HMM: 160-263/263
Sequence Identity: 49% (51 aa)

VGTPDYIAPEVLLKKG----YGMDCDWWSLGAIMFEMLVGYPPFYSDEPMNTCRKIVNWRTHLKFPQEARLSPEAKDLICRLLCDVEHRLGSRDTNEIKA
|||||||.||||  .|    || .||||| |  ..|||||  ||| |  . |  ||.. .. ||||... .| .||||||. | | |.|||    ..||.
VGTPDYISPEVLKSQGQDGEYGRECDWWSVGVFIYEMLVGDTPFYADSLVGTYSKIMDHKNSLKFPDDVEISKQAKDLICKFLTDREQRLGRNGVDDIKQ

IIYL
  . 
HKFF
Kinase NDR1_c.AA GEK 325-424 46 1e-33 110.24 In-house 162-269 (269) Show / Hide 
Range on Protein: 325-424
Range on HMM: 162-269/269
Sequence Identity: 46% (50 aa)

VGTPDYIAPEVL--LKKG---YGMDCDWWSLGAIMFEMLVGYPPFYSDEPMNTCRKIVNWRTHLKFPQEAR---LSPEAKDLICRLLCDVEHRLGSRDTN
|||||||.||.|  .  |   || .||||||| .|.||| |  |||..  ..|  ||.|.. |..||..     .| ||||||..|.|  |||||    .
VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQ

EIKAIIYL
. |   . 
DFKKHPFF
Kinase NDR1_c.AA Akt 326-435 42 5.6e-32 99.46 In-house 164-264 (264) Show / Hide 
Range on Protein: 326-435
Range on HMM: 164-264/264
Sequence Identity: 42% (48 aa)

GTPDYIAPEVLLKKGYGMDCDWWS-LGAIMFEMLVGYPPFYSDEPMNTCRKIVNWRTHLKFPQEARLSPEAKDLICRLLC-DVEHRLG--SRDTNEIKAI
||| |.|||.|...|... .|||. ||..|.||. | ||||..       || |    .|||   ..|||.|||| .||  | ..|||  . |..|||  
GTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKN--QPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIK--

IYLYFFQNLAHPFF
         .||.|
---------RHPWF
Kinase NDR1_c.AA Pkinase 325-435 29 1.6e-21 77.16 Pfam 172-293 (293) Show / Hide 
Range on Protein: 325-435
Range on HMM: 172-293/293
Sequence Identity: 29% (40 aa)

VGTPDYIAPEVLL-KKGYGMDCDWWSLGAIMFEMLVGYPPFYSD------EPMNTCRKIVNWRTHLKFPQEARLS-----------------PEAKDLIC
.|||.|.||||..  ..||  .|.||.| |..||| |.|||...      ..|   ..|   ..|  .|.. . |                 .|.||.|.
CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

RLLC-DVEHRLGSRDTNEIKAIIYLYFFQNLAHPFF
..|| | . |..              . | | ||.|
WCLCKDPKKRPT--------------AEQILQHPWF
Kinase NDR1_c.AA Pkinase_Tyr 120-266 28 4.3e-15 51.73 Pfam 1-159 (270) Show / Hide 
Range on Protein: 120-266
Range on HMM: 1-159/270
Sequence Identity: 28% (45 aa)

FELLTIIGRGAFGEVRLCRHK----ENGEIYAMKKLKKSEMLS-RGQVEHVRAERNLLAEV-DTHCIVKLHYSFQ-DAEY--LYLIMEYLPGGDMMTLLM
 ...  .|.||||||.... |    ...   | |.|| . | .     |   .| ... .  . . ||.|.     . |   .|..||| |.||. . | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

R----KDTLTEDEARFYVAQSVLAIESIHKHNYIHRDIKPDNLLLDKNGHMKLSDFGLCK
.    |. ||  .   . .|   . |  . .|.||||.   | |...|...| .||||..
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase NDR1_c.AA TyrKc 120-331 17 3.3e-12 -25.27 SMART 1-280 (280) Show / Hide 
Range on Protein: 120-331
Range on HMM: 1-280/280
Sequence Identity: 17% (51 aa)

FELLTIIGRGAFGEVRLCRHKENGEIYAMKKLKKSEMLSRGQVEHVRAERNLLAEV--DTHCIVKLHYSFQDA-------EYLYLIMEYLPGGDMMTLL-
 .|. ..|.||||||.... |   .  | |.||..       .|  . | ... ..  .  .||.|.    .        | |...||| |.||    | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

MRKDTLTEDEARFYVAQSVLAIESIHKHNYIHRDIKPDNLLLDKNGHMKLSDFGLCKPLDCN--------TLST----LHE-------------------
 ....|. ..   .  |     | .|..|.||||.   | |...|...| |||||.. ..          . ..                          
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

----------------NEEDEPREPM----DIDERLVSPSTGSSWRSQQEQ-----------------LLHWQKNRRM-LAFSTVGTPDYI
                   ..| . |      .....        . | .                  .  |. .  .   ||..   ...
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase NDR1_c.AA S_TK_X 436-502 23 2.9e-09 38.0 SMART 1-79 (79) Show / Hide 
Range on Protein: 436-502
Range on HMM: 1-79/79
Sequence Identity: 23% (23 aa)

RGIDWDHLY----EVEAAFKPEVN----GELDTQNFQ-KFEEAGTQGDLPSKSGQWRKVCLLDFRDVN--------------------FVGYTYKN
||||||.||    |.|. |||...    .. || ||  .|.|.                      ...                    | |.||..
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-----------------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF