Gene MAST_c-1 (S.moellendorffii)
MAST_c-1
Species: S.moellendorffii
Alias: MAST_c-1
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
MAST_c-1.AA | Protein | None | 972 | None | Fasta, JSON |
MAST_c-1.NA | RNA | None | 2919 | None | Fasta, JSON |
MAST_c-1.kin_dom | Protein Kinase Domain | None | 287 | None | Fasta, JSON |
Protein domains of MAST_c-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
---|---|---|---|---|---|---|---|---|---|
Kinase | MAST_c-1.AA | AGC | 565-851 | 33 | 3.2e-175 | 457.61 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 565-851 Range on HMM: 1-395/395 Sequence Identity: 33% (135 aa) FEIIKPISRGAFGRVFLARKR------TTGDLFAIKVLRKAD---MIRKNAVESVHAE------------RNILIHAK----------NPFLVR-FFYSF ||..|.|..|.||.|.|.||. .||...|.|||.|.. ...|| || ...| |||| ... .||.|. .||| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF TCKEN--LYLVMEYLN--------GGDMYSMLRNLG-----CLDEDMARYYIAE-------LVLALEYLHS-LAVIHRD-LKPDNILIAHDGHIRLTDFG |.. ||.||||.. ||.. ..|.. | ..||..||.|.|| .||||||||| . .|||| |||.|||. .||||.||||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LSKVGLINSTDDLSAPASRGATVAAEKHDSSDSS---------------------------TKKGRQQKTVG--TPDYLAPEILLGTAHGYPADWWS--V |.|.| . ... ..| . .. |.. . |. | . .| ||.|.||||| .|...|||| . LCKEGMNDGEKGQQ-SQSN--MKFHW-HNKKY-QKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGL GVILFEFLTGIPPFNAEDPQ----------MIFENILNR------NIPWP-----NIPG--DMSFEAADFIDKLLAEDPNHRLGAK-------GAAEVKA |....|.|||.|||....|| .|..|.|. ....| ..|. .| || |.| ||| ||..|||.. || |.|. GCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKN HPFF ||.| HPWF |
|||||||||
Kinase | MAST_c-1.AA | MAST | 565-851 | 43 | 1.9e-171 | 528.63 | In-house | 1-337 (337) | Show / Hide |
Range on Protein: 565-851 Range on HMM: 1-337/337 Sequence Identity: 43% (147 aa) FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHAKNPFLVRFFYSFTC--KENLYLVMEYLNGGDMYSMLRNLG-CLD ||.||.||.||.|.|.|.....|.|.||.||... |.|.|| |..| .||||| ..||| | .|||| |. |..||||..||| | ||..| |.. FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP EDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSKVGLIN-----------------STDDLSAPASRGATV----AAEKHDSSD |.||. ||||.||.|||||| . .||||||||.|| .||| ||||||||||... ..... . .. . . EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN SSTK-----------------KGRQQKTVGTPDYLAPEILLGTA-HGYPADWWSVGVILFEFLTGIPPFNAEDPQ-MIFENILN--RNIPWPNI-----P .. . . .... .|||||.|||..||. .| |.||||.|.|..|||.|.||||.. |. |||.||.| |.| || . QIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDD GDMSFEAADFIDKLLAEDPNHRLGAKGAAEVKAHPFF || || | |.|||. .| ||||.||.|.| |||| DCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF |
|||||||||
Kinase | MAST_c-1.AA | MAST | 565-851 | 45 | 4.3e-164 | 533.16 | In-house | 1-334 (334) | Show / Hide |
Range on Protein: 565-851 Range on HMM: 1-334/334 Sequence Identity: 45% (153 aa) FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHAKNPFLVRFFYSFTCKENLYLVMEYLNGGDMYSMLRNLGCLDEDM ||.|||||.||.|.|.|.....|.|.||.||..|.|||.|| |..| .||||| ..||| | .|||| |..|..||||..||| | |...|..||.| FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM ARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSKVGLINSTDDLSAPASRGATVAAEKHDSSDSSTKKGR----------------- |. ||||.||.|||||| . .||||||||.|| .||| ||||||||||... . . .. .. . ... .. . AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ --------------------QQKTVGTPDYLAPEILLGTA-HGYPADWWSVGVILFEFLTGIPPFNAEDPQMIFENILNRN---IPWPNI-----PGDMS ... .|||||.|||..||. || | ||||.|.|..|||.|.|||| ..|..||.|||||| | || || QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS FEAADFIDKLLAEDPNHRLGAK-GAAEVKAHPFF || | |.|||. ||. ||||. ||.||| |||| PEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF |
|||||||||
Kinase | MAST_c-1.AA | NDR | 565-851 | 37 | 2.3e-145 | 451.66 | In-house | 1-350 (350) | Show / Hide |
Range on Protein: 565-851 Range on HMM: 1-350/350 Sequence Identity: 37% (132 aa) FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHAK--NPFLVRFFYSFTCKENLYLVMEYLNGGDMYS---MLRNLGC |||||.|..||||.|.|.||. ||...|.|..||..|..|| | .| ||| |. |. ||. |. .||| | .|||||||. |||| . .| .... FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI LDEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSKVGLI---------------------NSTDDLSAPASRGATV---AAEK ..||.|| ||||.|.|.|..|.. ||||.||||.|| |||| ||||||.. |.| . ... .... .... FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN HDSSDSST--------------------KKGRQQ-----KTVGTPDYLAPEILLG-TAHGYPADWWSVGVILFEFLTGIPPFNAEDPQMIFENILNRNIP ...... .. ... .|||||||.|||.... | .. ||||.|.|..|.|.|.|||....|| ....|.| . SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT WP----NIP--GDMSFEAADFIDKLLAEDPNHRLGA--KGAAEVKAHPFF |. ..| .| ||.| | .|.. ||.||||. ||. |.|.|||| WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF |
|||||||||
Kinase | MAST_c-1.AA | AktR | 565-851 | 33 | 4.90000000001e-110 | 371.87 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 565-851 Range on HMM: 1-268/268 Sequence Identity: 33% (101 aa) FEIIKPISRGAFGRVFLARKR-TTGDLFAIKVLRKADMIRKNAVESVHAERNILI-HAKNPFLVRFFYSFTCKENLYLVMEYLNGGDMYSMLRNLGCLDE |...|.. .||||.|.|..|. ......|.|...| ..|..|. . . ||||.. ....||.|...|.| ||.|...||| ||.....|.. . ..| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE DMARYYIAELVLALEYLHSL-AVIHRDLKPDNILIAHDGHIRLTDFGLSKVGLINSTDDLSAPASRGATVAAEKHDSSDSSTKKGR-----QQKTVGTPD ..|| |.|. .|||||||. .| |||||.|||. |||...||||||| . . ... .||| EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-------------------------------LQFMMHYDEKAYSFCGTPE YLAPEILLG-TAHGYPADWWSVGVILFEFLTGIPPFNAEDPQMIFENILNRNIPWPNIPGDMSFEAADFID-KLLAEDPNHRLG--AKGAAEVKAHPFF |.|||... |....|||..|. ..| .||.|||.... . .|..|.. .. ...| . |... |.| ||| .||.||| ..|. |.| ||.| YMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
|||||||||
Kinase | MAST_c-1.AA | S_TKc | 565-851 | 33 | 9.1e-107 | 361.92 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 565-851 Range on HMM: 1-231/231 Sequence Identity: 33% (100 aa) FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHAKNPFLVRFFYSFTCKENLYLVMEYLNG--GDMYSMLRNLGC--- .||...| .||||.|...|.. || ..|||... |.. |..|| . . |..|.....| ..||.||||..| ||....... |. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LDEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSKVGLINSTDDLSAPASRGATVAAEKHDSSDSSTKKGRQQKTVGTPD ..| .||.|......||||.||. .|||||||.|||. . || ..||||... .|||. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------------------------------TTFCGTPW YLAPEILLGTAHGY-PADWWSVGVILFEFLTGIPPFNAEDPQMIFENILNRNIPWPNIPGDMSFEAADFIDKLLAEDPNHRLGAKGAAE----VKAHPFF |.|||.| .|. ..||||.|.||.|.|.| ||| ..||.|..|. | || |||.|.| ||..|..| | . .|.||.| YMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||
Kinase | MAST_c-1.AA | RSK | 568-851 | 34 | 4.2e-99 | 335.56 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 568-851 Range on HMM: 1-278/278 Sequence Identity: 34% (107 aa) IKPISRGAFGRVFLARKR---TTGDLFAIKVLRKADMIRKNA-VESVHAERNILIHAK-NPFLVRFFYSFTCKENLYLVMEYLNGGDMYSMLRNLGC--- .| .|..| ||| || || ..| |||.|| ..... .. . .||||| . . ||.|. .|.| .. |||.|||..||... |.. .. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LDEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAH---DGHIRLTDFGLSKVGLINSTDDLSAPASRGATVAAEKHDSSDSSTKKGRQQKTVGTPD ..|| |..|.||.|||.|.||.. .|||||||.||| .. .|||.|||||..| . . .... .. ..| . FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF---------------------------RCDHNQWTMTFCYTIE YLAPEILL----GTAHGYPADWWSVGVILFEFLTGIPPFNA---EDPQMIFENILNRNIPWPNIP--GDMSFEAADFIDKLLAEDPNHRLG--AKGAAEV |.|||.| . .|. .|||| ||...| ||| ||| . .... |...|.. .. ...| .| || |.| |.| ||. ||| ..|.|. YMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFS-LTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEI KAHPFF |.||.| KQHPWF |
|||||||||
Kinase | MAST_c-1.AA | Pkinase | 565-851 | 27 | 5.3e-85 | 293.5 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 565-851 Range on HMM: 1-293/293 Sequence Identity: 27% (90 aa) FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVH-AERNILIHAKNPFLVRFFYSFTCKENLYLVMEYLNGG----DMYSMLR--NL ..|...| .|.||.|...... ||...|.|...| . . .. .. .| |. . . |. ||....|. | ..|.||||..|| | ..... . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GCL--DEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHI----RLTDFGLSKVGLINSTDDLSAPASRGATVAAEKHDSSDSSTKKGRQQKT ||. .|. .. |. ... .|||.|| .|||||||.|||| ..||| ...||||.|. ... . GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---------------------------Y-NNS-MTTF VGTPDYLAPEILL-GTAHGYPADWWSVGVILFEFLTGIPPFNAE------DPQMIFENILNRNIPWPNIPGD------------------MSFEAADFID .|||.|.|||... |. .|...|.||.|.||.|.|.| ||| . |.. ....|. . .... . .| |. |||. CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK KLLAEDPNHRLGAKGAAEVKAHPFF ..|. ||. |.. |.... ||.| WCLCKDPKKRPT---AEQILQHPWF |
|||||||||
Kinase | MAST_c-1.AA | MASTL | 565-714 | 53 | 1.1e-74 | 254.42 | In-house | 1-151 (283) | Show / Hide |
Range on Protein: 565-714 Range on HMM: 1-151/283 Sequence Identity: 53% (81 aa) FEIIKPISRGAFGRVFLA-RKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHAKNPFLVRFFYSFTCKENLYLVMEYLNGGDMYSMLRNLGCLDED | |.|||||||||.|.| . . |.|.||..||||| || . | |||. | | .| | .|| ..||||||. |||. |.| | ||. FVIVKPISRGAFGKVYLGYKNQKGKKLYAVKVMKKADMINKNMTHQVQAERDALALSKSQFCVHLYYSLQSASYVYLVMEYMIGGDVKSLLHMYGYFDEE MARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSKVGL ||..||.|.|.||.||| .||||.||||.|| .|||.||||||||| . MAIKYISEMVMALDYLHRHGIIHRDIKPDNMLISNEGHIKLTDFGLSKVTM |
|||||||||
Kinase | MAST_c-1.AA | Akt | 565-715 | 49 | 2.1e-74 | 237.23 | In-house | 1-153 (264) | Show / Hide |
Range on Protein: 565-715 Range on HMM: 1-153/264 Sequence Identity: 49% (75 aa) FEIIKPISRGAFGRVFLARKRTTGDLF-AIKVLRKADMIRKNAVESVHAERNILIHAKNPFLVRFFYSFTCKENLYLVMEYLNGGDMYSMLRNLGCLDED |...| . .|.||.|||..| |.... |.|||.| | || || . .||||| | ..||.| ||| ...||.||.| |||. .. |. . .|| FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED MARYYIAELVLALEYLHSLAVIHRD-LKPDNILIAHDGHIRLTDFGLSKVGLI ||.|.||..||.|.||| .| || ||| |||. .||||.||||||.| ..| RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENII |
|||||||||
Kinase | MAST_c-1.AA | SGK | 565-711 | 40 | 1.4e-72 | 223.34 | In-house | 1-173 (283) | Show / Hide |
Range on Protein: 565-711 Range on HMM: 1-173/283 Sequence Identity: 40% (70 aa) FEIIKPISRGAFGRVFLARKRTT------------------GDLFAIKVLRKADMI-------RKNAVESVHAER-NILIHAKNPFLVRFFYSFTCKENL |...| | | ||.|..... . ....|.|||.|. | .|. . . ||| .|| | ||.| |.| |. | FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL YLVMEYLNGGDMYSMLRNLGCLDEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSK |.||.|.|||.| . |. ... || || | ||.|.|||||||. .|.|||||.||| |.||..||||||.| YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCK |
|||||||||
Kinase | MAST_c-1.AA | PKA | 565-711 | 48 | 2.8e-65 | 223.16 | In-house | 1-149 (263) | Show / Hide |
Range on Protein: 565-711 Range on HMM: 1-149/263 Sequence Identity: 48% (73 aa) FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHAKNPFLVR-FFYSFTCKENLYLVMEYLNGGDMYSMLRNLGCLDED ||||. . .| |||| |.|....|. .|.|.|.|.. .| . || || |.||| |.||.|. ..| . .||.|||| .||.| | ||. |..... FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP MARYYIA-ELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSK .|. |.| . |||||||||. |.||||| |||| .||| .|||| .| HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAK |
|||||||||
Kinase | MAST_c-1.AA | SGK | 753-851 | 45 | 1e-43 | 132.58 | In-house | 187-283 (283) | Show / Hide |
Range on Protein: 753-851 Range on HMM: 187-283/283 Sequence Identity: 45% (45 aa) GTPDYLAPEILLGTAHGYPADWWSVGVILFEFLTGIPPFNAEDPQMIFENILNRNIPWPNIPGDMSFEAADFIDKLLAEDPNHRLGAK-GAAEVKAHPFF ||| |||||.|.. |. |||. | .|.|...|.||| . | ..||.| . .|| || .| | | ||. || |||.| ...|.| |||| GTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPL---QIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
|||||||||
Kinase | MAST_c-1.AA | Akt | 753-851 | 42 | 6.1e-43 | 135.05 | In-house | 164-264 (264) | Show / Hide |
Range on Protein: 753-851 Range on HMM: 164-264/264 Sequence Identity: 42% (43 aa) GTPDYLAPEILLGTAHGYPADWWS-VGVILFEFLTGIPPFNAEDPQMIFENILNRNIPWPNIPGDMSFEAADFIDKLLAEDPNHRLG--AKGAAEVKAHP ||| |||||||.|. |. ..|||. .|....|...| ||| ..| . |..|.| .. |. | |. |.| .|| ||..||| ..| |.|.|| GTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDK-DWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHP FF .| WF |
|||||||||
Kinase | MAST_c-1.AA | PKA | 753-851 | 38 | 2.4e-33 | 117.13 | In-house | 160-263 (263) | Show / Hide |
Range on Protein: 753-851 Range on HMM: 160-263/263 Sequence Identity: 38% (41 aa) GTPDYLAPEILLGT-AHGYPADWWSVGVILFEFLTGIPPFNAE--DPQMIFENILNRNIPWPNIPGDMSFEA---ADFIDKLLAEDPNHRLGAKGA--AE |||.||||||.... || . |||. |.. .|.|.|.|||... || |.| |.| | .|. .. | |.|.|||. |.. |.| . . GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPR---HFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVND VKAHPFF .| |..| IKNHKWF |
|||||||||
Kinase | MAST_c-1.AA | MASTL | 753-851 | 33 | 4.3e-26 | 86.18 | In-house | 166-283 (283) | Show / Hide |
Range on Protein: 753-851 Range on HMM: 166-283/283 Sequence Identity: 33% (41 aa) GTPDYLAPEILLGTAHGYPADWWS-VGVILFEFLTGIPPFNAEDPQMIFENILNRNIPWPNIPGDMS---------------------FEAADFIDKLLA ||||||.|| .. || |||. || ..||..|||||. | |. |.|||.|.. || .| .. . |..|| GTPDYLKPEQDYQQTHGQVVDWWASLGVCFYEFMKGIPPFCDESPCKVFQNILSRDLEWPMGDEQKSTTPYSSKLLKSCFETVASNPEVPVMCLIENLLQ EDPNHRLGAKGAAEVKAHPFF .|. | |. .|. | | MRPRDRPSAT---DVQQHTFI |
|||||||||
Kinase | MAST_c-1.AA | Pkinase_Tyr | 565-711 | 27 | 4.7e-20 | 68.54 | Pfam | 1-159 (270) | Show / Hide |
Range on Protein: 565-711 Range on HMM: 1-159/270 Sequence Identity: 27% (44 aa) FEIIKPISRGAFGRVFLARKR----TTGDLFAIKVLRKADMIRKN-AVESVHAERNILIHA-KNPFLVRFFYSFTCK-EN--LYLVMEYLNGGDMYSMLR ...| . .||||.|.... . |. |.|.| | . .. |. .| .|. . ..| .||. |.. | .|.|||| .||... || ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR N----LGCLDEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSK . . |. . . .. ..|||.| ||||| |.|........ .||||.. KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR |
|||||||||
Kinase | MAST_c-1.AA | TyrKc | 565-851 | 21 | 1.6e-14 | 12.03 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 565-851 Range on HMM: 1-280/280 Sequence Identity: 21% (68 aa) FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHA--KNPFLVRFFYSFTCK-------ENLYLVMEYLNGGDMYSMLR . .| . .||||.|.... . |.|.|.. .| . | .|. . ..| .||.. | . | |..|||| .|| . || ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR NLGC-LDEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSKVGLIN-----STDDLSA---PASRG-ATVAAEKHDSSDSSTKK . . | . .. ||||| .||||| |.|........ .|||||. . |.| .. ... . KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR------------- GRQQKTVGTPDYLAPEILLGTAHGYPADWWSVGVILFEFLT-GIPPFNA-----EDPQMIFENILNRNIPWPNIPGD--------MSFEAADFIDKLLAE .||| . | || || ..| .| | .| ..| ..|.. ... . . | . .. | . . . .| -----------WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQ--PPNDYPMSFVCCPDEMYQIMKQCWHE DPNHRLGAKGAAEVKAHPFF ||. | . | .| DPEDRPTFSEI-----HECF |
|||||||||
Kinase | MAST_c-1.AA | APH | 659-713 | 15 | 0.003192 | 11.87 | Pfam | 150-205 (248) | Show / Hide |
Range on Protein: 659-713 Range on HMM: 150-205/248 Sequence Identity: 15% (9 aa) CLDEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIA-HDGHIR---LTDFGLSKVG .. ..... .|.| .. ....|.|..|.|... ... | . |.. . .| DRQWWLWQRLWAWLEAHWP---PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWG |
|||||||||
Kinase | MAST_c-1.AA | APH | 567-651 | 20 | 1.600579 | 2.66 | Pfam | 1-86 (248) | Show / Hide |
Range on Protein: 567-651 Range on HMM: 1-86/248 Sequence Identity: 20% (19 aa) IIKPISRGAFGRVFLARKRTTG-DLFAIKVLRKADMIRKNAVESVHAERNILIH-AKNPF--LV-RFFY-----SFTCKENLYLVMEYLNGGDMY ..||| |. .|... . . ... .. ... . |..|.|. .| | |.... | | .. .| . ....||.| | | . WWRPISGGWSNRTYYRTTDD-RPRYV-LRRYPPP-----WWAEELHREHRWLRHLAAHGIPVPVPRVLWGCTDDEFHGW--PWYLMEWLPGEDLW |