Gene TIF1D (Mouse)

TIF1D

Species: Mouse
Alias: TIF1D
External Links:
Annotation:

Classification

Group: Atypical
Family: TIF1

Sequence

Name Sequence Type Origin Length Description Download
TIF1D.AA Protein None 1242 None Fasta, JSON
TIF1D.NA RNA None 9192 None Fasta, JSON

Protein domain

Protein domains of TIF1D.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Zf-B_box TIF1D.AA zf-B_box 61-101 28 1.5e-07 34.5 Pfam 1-45 (45) Show / Hide 
Range on Protein: 61-101
Range on HMM: 1-45/45
Sequence Identity: 28% (13 aa)

FALYCPLHTQEVLKLFCETCDVLTCHSCLMVEHKE-----HRCRHV
 . |||.| .| |...|..|... |..|.. .||      |... .
QM-YCPEHPEEPLEYYCQDCQQCICEDCAVHGHKGNGFKKHTVVPI
BBOX TIF1D.AA BBOX 60-101 23 1.5e-05 25.71 SMART 1-51 (51) Show / Hide 
Range on Protein: 60-101
Range on HMM: 1-51/51
Sequence Identity: 23% (12 aa)

DFALYCPLHT-QEVLKLFC-ETCDVLTCHSCLMV-EH------KEHRCRHV
. ...|. |   |....|| |.|... |  | .. ||      . |. . .
HRPPMCDNHQQHEPAHFFCVEDCQQCLCWDCDESGEHQANKLFRGHQVVPL
Zf-B_box TIF1D.AA zf-B_box 1-35 21 0.002444 17.87 Pfam 1-40 (45) Show / Hide 
Range on Protein: 1-35
Range on HMM: 1-40/45
Sequence Identity: 21% (9 aa)

MARNCSECKEKRAAHILCTYCNRWLCSSCTEE-H-R-----H
 . .|.|..|.. ... |. |.. .| .|... | .     |
QM-YCPEHPEEP-LEYYCQDCQQCICEDCAVHGHKGNGFKKH
BBOX TIF1D.AA BBOX 1-38 24 0.009343 1.14 SMART 2-51 (51) Show / Hide 
Range on Protein: 1-38
Range on HMM: 2-51/51
Sequence Identity: 24% (12 aa)

MARNCSECKEKRAAHILC-TYCNRWLCSSCTEE--H---------RHVPA
 .. |.... .. ||. |   |  .||  |.|.  |         . || 
RPPMCDNHQQHEPAHFFCVEDCQQCLCWDCDESGEHQANKLFRGHQVVPL
PHD TIF1D.AA PHD 4-69 17 0.031465 4.48 SMART 1-39 (39) Show / Hide 
Range on Protein: 4-69
Range on HMM: 1-39/39
Sequence Identity: 17% (12 aa)

NCSECKEKRAAHILCT-YCNRWLCSSCTEEHRHVPAPGGPLFARAQKGSSGVNGGSGDFALYCPLHT
 |  |..     |.|   |.||    |     .                        |.  ||| ..
YC-VCGK--G-MIQCDPGCDRWYHQ-CLGPPLE----------------------PPDG-WYCPRCR
PHD TIF1D.AA PHD 24-32 33 1.396738 3.41 Pfam 46-54 (54) Show / Hide 
Range on Protein: 24-32
Range on HMM: 46-54/54
Sequence Identity: 33% (3 aa)

WLCSSCTEE
|.| .|...
WYCPRCKCC
BBC TIF1D.AA BBC 108-234 28 9.9e-42 145.88 SMART 1-132 (132) Show / Hide 
Range on Protein: 108-234
Range on HMM: 1-132/132
Sequence Identity: 28% (38 aa)

QRMLLESVTSQVAHKKSSLQTSAKQIEDRIFEVK-----HQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNERKRKLEQQLQSIMVLNRQFEHVQ
.|. ||.. ... .|.. .. ..|||...| .|.     ..|..||..|... . |||.||.. . ....|. ........|.||.|.......|.||..
HREKLEQHLTKLRKKHWECEDAMKQIQNIIQQVQPGHVDENHEDVEQCIRAHFDDLMNWLNRRKKMMLMDLDEQCENKQKWLMQQMQTMTQKQEQLEHCC

NFINWAVCSKSSVPFLFSKELIVFQMQRLLET
.|..||......  ||.||.||.||...|.. 
QFCQWALNMGDCTEFLQSKKLIIFQCCHLHKQ
PHD TIF1D.AA PHD 998-1043 37 2.7e-16 52.48 Pfam 1-54 (54) Show / Hide 
Range on Protein: 998-1043
Range on HMM: 1-54/54
Sequence Identity: 37% (20 aa)

FCAVCIN-----GGELLCCD-RCPKVYHLSCHVPALL--SFPGGEWVCTLCRSL
.|.||       .|...|||  ||. .|..|| | |     |.|||.|. |.. 
YCCVCQKCDWDDDGDMICCDNGCPRWFHQYCHGPPLEPEEIPEGEWYCPRCKCC
PHD TIF1D.AA PHD 998-1041 40 1.7e-12 48.79 SMART 1-39 (39) Show / Hide 
Range on Protein: 998-1041
Range on HMM: 1-39/39
Sequence Identity: 40% (18 aa)

FCAVCINGGELLCCD-RCPKVYHLSCHVPALLSFPGGEWVCTLCR
.| ||   | ...|| .|.. ||. |. |.|.  | | |.|  ||
YC-VCGK-G-MIQCDPGCDRWYHQ-CLGPPLE-PPDG-WYCPRCR
BROMO TIF1D.AA BROMO 1069-1175 36 3.3e-29 104.28 SMART 1-118 (118) Show / Hide 
Range on Protein: 1069-1175
Range on HMM: 1-118/118
Sequence Identity: 36% (44 aa)

SMYDQKKCEKLVLSLCCNSLSL------------PFHEPVSPL---ARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDS
..  ||||..|  .. |   .             ||..||..    .  ||.|||.||||. |..||..    .|...|| | |..|||.|| ..| |||
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENH---QYQSMEEFVDDFMLMFNNCMTYNEPDS

EVAEAGRCLEVFFEGWLKEIYP
|| .... |. ||| ...|..|
EVYKMAKKLQKFFEEKWREFPP
Bromodomain TIF1D.AA Bromodomain 1076-1161 32 1.5e-20 69.3 Pfam 1-89 (89) Show / Hide 
Range on Protein: 1076-1161
Range on HMM: 1-89/89
Sequence Identity: 32% (30 aa)

CEKLVL--SLCCNSLSLPFHEPV---SPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYT-TPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRC
|....    .  . .. ||..||         ||.|||.||||| |..||   .  .|. ...|.  |..||. || ..| |||..... | 
CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKL---KNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK