Gene PAN3 (Human)

PAN3

Species: Human
Alias: PAN3
External Links:
Annotation:

Classification

Group: Other
Family: PAN3

Sequence

Name Sequence Type Origin Length Description Download
PAN3.AA Protein None 887 None Fasta, JSON
PAN3.NA RNA None 5643 None Fasta, JSON
PAN3.kin_dom Protein Kinase Domain None 239 None Fasta, JSON

Protein domain

Protein domains of PAN3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ZnF_C3H1 PAN3.AA ZnF_C3H1 45-70 29 1.1e-05 26.13 SMART 1-31 (31) Show / Hide 
Range on Protein: 45-70
Range on HMM: 1-31/31
Sequence Identity: 29% (9 aa)

KLK--YCRYYAKDK---TCFYGEECQFLHED
. |   |.|...     .| ||..|.|.| .
RYKTPPCKYFMRRGPPWYCPYGDRCKFAHPP
Zf-CCCH PAN3.AA zf-CCCH 44-70 37 3.1e-05 21.41 Pfam 1-27 (27) Show / Hide 
Range on Protein: 44-70
Range on HMM: 1-27/27
Sequence Identity: 37% (10 aa)

VKLKYCRYYAKDKTCFYGEECQFLHED
 | . |||...  .| ||. |.| | .
YKTELCRYFMRTGYCPYGDRCKFAHPQ
Kinase PAN3.AA NEK6 611-651 41 4e-06 16.04 In-house 99-139 (252) Show / Hide 
Range on Protein: 611-651
Range on HMM: 99-139/252
Sequence Identity: 41% (17 aa)

LLPESLIWAYIVQLSSALRTIHTAGLACRVMDPTKILITGK
|.||  || | |||.|||  .|   .  | . |  . ||..
LIPERTIWKYFVQLCSALEHMHSKRVMHRDIKPANVFITAN
Kinase PAN3.AA S_TKc 502-749 14 2.9e-05 -99.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 502-749
Range on HMM: 1-231/231
Sequence Identity: 14% (45 aa)

YIT----------SCYKAVNSKDDLPYCLRRIHGFRLVNTKCMVLVDMWKKIQHSNIVTLREVFTTKAFAEPSLVFAYDFHAG--GETMMSRHFNDPNAD
|            ..||... |..  . . .|.       . .  ... || .| |||.| .|| .      .| .  ..  |  |. .   . . ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRH--

AYFTKRKWGQHEGPLPRQHAGL---LPESLIWAYIVQLSSALRTIHTA-----------------------GLACRVMDPTKILITGKTRLRVNCVGVFD
                    ||   .||  .. |. |. .||  .|                         |||...                 ..|  .
--------------------GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL---------------TTFCGTPW

-----VLTFDNSQNNNPLALMAQYQ--QADLISLGKVVLALAC-NSLAGIQRENLQKAMELVTINYSSDLKNLILYLLT-D-QNRMRSVNDIM-------
     ||               .|    .|  |.| ..  ..|   .      ..|. ....    |...|..|  .|. | ..|.              
YMAPEVL---------------GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

-PMI
 | .
HPWF
Kinase PAN3.AA CDK 541-569 31 0.000141 10.38 In-house 63-99 (284) Show / Hide 
Range on Protein: 541-569
Range on HMM: 63-99/284
Sequence Identity: 31% (12 aa)

KKIQHSNIVTLREVFTTKAFA---------EPSLVFAY
|.. | |||.|..|..||. .           ..|| |
KEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY
Kinase PAN3.AA NEK6 493-549 24 0.018292 3.64 In-house 2-62 (252) Show / Hide 
Range on Protein: 493-549
Range on HMM: 2-62/252
Sequence Identity: 24% (15 aa)

RIQKSSNFGYITSCYKAVNSKDDLPYCLRRIHGFRLVNTK----CMVLVDMWKKIQHSNIV
.| |    |     |.|    ||..  |...  | ..  |    |.  .|. |...| |..
QIEKKIGKGQFSEVYRAQCLWDDKHVALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPNVI