Gene TXNDC3 (Human)

TXNDC3

Species: Human
Alias: TXNDC3
External Links:
Annotation:

Classification

Group: NDK
Family: NDK

Sequence

Name Sequence Type Origin Length Description Download
TXNDC3.AA Protein None 588 None Fasta, JSON
TXNDC3.NA RNA None 2327 None Fasta, JSON
TXNDC3.kin_dom Protein Kinase Domain None 134 None Fasta, JSON

Protein domain

Protein domains of TXNDC3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
NDK TXNDC3.AA NDK 158-220 38 4.1e-07 28.28 Pfam 5-67 (140) Show / Hide 
Range on Protein: 158-220
Range on HMM: 5-67/140
Sequence Identity: 38% (24 aa)

AIIKPDAVISKKVLEIKRKITKAGFIIEAEHKTVLTEEQVVNFYSRIADQCDFEEFVSFMTSG
..||||||   .. || ... ..|| | |   ..||.||.  .|.  ..   |.. |.|||||
IMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMHLTREQAEEHYAEHKGKPFFPDLVEFMTSG
NDK TXNDC3.AA NDK 315-455 28 5.8e-53 183.19 SMART 1-142 (142) Show / Hide 
Range on Protein: 315-455
Range on HMM: 1-142/142
Sequence Identity: 28% (41 aa)

LEKTLALLRPNLF-HERKDDVLRIIKDEDFKILEQRQVVLSEKEAQALCK-EYENEDYFNKLIENMTSGPSLALVLLRDNGLQYWKQLLGPRTVEEAIEY
.|.|.....|.   .. ........... |||. .....|....|.  .. | . ...||.|.| |||||..|.|. ..|  ..|....||. .|.. | 
MERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMQLTKEQAEEHYAVEHKGKPFFNDLVEFMTSGPVVAMVWEGENAIKTWRTMMGPTNPEVPKEA

FPESLCAQFAMDSLPVNQLYGSDSLETAEREIQHFFPLQSTLG
 |......|.. . . |  .||||.|.|||||...|| .....
APGTIRGDFGT-DIGRNIVHGSDSPESAEREIAYWFPESEICE
NDK TXNDC3.AA NDK 456-588 34 9.3e-49 169.22 SMART 7-142 (142) Show / Hide 
Range on Protein: 456-588
Range on HMM: 7-142/142
Sequence Identity: 34% (47 aa)

LIKPHAT-SEQREQILKIVKEAGFDLTQVKKMFLTPEQIEKIYP-KVTGKDFYKDLLEMLSVGPSMVMILTKWNAVAEWRRLMGPTDPEEAKLLSPDSIR
.|||.|.  .  ..|. .....|| ... | |.||.|| |. |     ||.|..|| |. . ||...|.. ..||...||..||||.||..|   |..||
MIKPDAVQRGLIGEIISRFERKGFKIVAMKMMQLTKEQAEEHYAVEHKGKPFFNDLVEFMTSGPVVAMVWEGENAIKTWRTMMGPTNPEVPKEAAPGTIR

AQFGISKLKNIVHGASNAYEAKEVVNRLFEDP-EEN
..||... .|||||  .  .|.  .. .| .    .
GDFGTDIGRNIVHGSDSPESAEREIAYWFPESEICE
NDK TXNDC3.AA NDK 451-575 35 3.2e-34 124.81 Pfam 1-128 (140) Show / Hide 
Range on Protein: 451-575
Range on HMM: 1-128/140
Sequence Identity: 35% (46 aa)

QSTLGLIKPHATS-EQREQILKIVKEAGFDLTQVKKMFLTPEQIEKIYPKVTGKDFYKDLLEMLSVGPSMVMILTKWNAVAEWRRLMGPTDPEEAKLLSP
. |. .|||.|       .|..   ..|| . . | | ||.|| |. |    || |..|| |  . || ..|.. . ||...|| .||.|.|.|||   |
ERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMHLTREQAEEHYAEHKGKPFFPDLVEFMTSGPVVAMVWEGENAIKKWREMMGATNPAEAK-EAP

DSIRAQFGISK--LK-NIVHGASNAYEAK
..||..|..|    . |.|||   .  |.
GTIRGDFAVSIYPGRRNVVHGSDSPESAE
NDK TXNDC3.AA NDK 316-450 28 2.2e-20 76.71 Pfam 1-140 (140) Show / Hide 
Range on Protein: 316-450
Range on HMM: 1-140/140
Sequence Identity: 28% (40 aa)

EKTLALLRPNLFHER-KDDVLRIIKDEDFKILEQRQVVLSEKEAQALCKEYENEDYFNKLIENMTSGPSLALVLLRDNGLQYWKQLLGPRTVEEAIEYFP
|.|.... |   . .  ..... . .  |||  .. ..|.. .|..  .| .   .|. |.| ||||| .|.|. ..|    | ...|.   .||    |
ERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMHLTREQAEEHYAEHKGKPFFPDLVEFMTSGPVVAMVWEGENAIKKWREMMGATNPAEAK-EAP

ESLCAQFAMD---SLPVNQLYGSDSLETAEREIQHFFP---L
 .. ..||..   .   |   ||||.|.|||||  .||   .
GTIRGDFAVSIYPGR-RNVVHGSDSPESAEREIAFWFPPEEI