Gene NME7a (Human)
NME7a
Species: Human
Alias: NME7a
External Links:
Annotation:
Sequence
Protein domains of NME7a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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NDK | NME7a.AA | NDK | 91-229 | 41 | 9.7e-68 | 232.28 | SMART | 1-142 (142) | Show / Hide |
Range on Protein: 91-229 Range on HMM: 1-142/142 Sequence Identity: 41% (59 aa) KEKTLALIKPDAI--SKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHV-DHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTD .|.|...|||||. . ||||... ..||.|...||| |....| ... .|...||||.|..|.| ||..||.. ...||..|....|| |..|.. MERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMQLTKEQAEEHYAVEHKGKPFFNDLVEFMTSGPVVAMVWEGENAIKTWRTMMGPTNPEVPKEA ASESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCG | ..||. |||| ||. || ||..||.||....||.| |. APGTIRGDFGTDIGRNIVHGSDSPESAEREIAYWFPESEICE |
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NDK | NME7a.AA | NDK | 92-227 | 37 | 6.5e-54 | 190.22 | Pfam | 1-140 (140) | Show / Hide |
Range on Protein: 92-227 Range on HMM: 1-140/140 Sequence Identity: 37% (53 aa) EKTLALIKPDAI--SKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDAS |.|...|||||. . ||||. . ..||.| .|||.|.| .| . .|. .|||..|..|.| ||..|| . ...|| .| ..|. | |. | ERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMHLTREQAEEHYAEHKGKPFFPDLVEFMTSGPVVAMVWEGENAIKKWREMMGATNPAEAK-EAP ESIRALFGTDG--IR-NAAHGPDSFASAAREMELFFPSSGG .||. |... | |. || || .||.||. ..|| . GTIRGDFAVSIYPGRRNVVHGSDSPESAEREIAFWFPPEEI |
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DM10 | NME7a.AA | DM10 | 3-91 | 21 | 7.1e-41 | 143.03 | SMART | 1-126 (126) | Show / Hide |
Range on Protein: 3-91 Range on HMM: 1-126/126 Sequence Identity: 21% (27 aa) HSERFVFIAEWYDPNA------SLLRRYELLFYPGDGSVEMH--DVKNH-----RTFLKRTKYDN------------------------LHLEDLFIGNK ..... |.|.|.|... ...||.....|..|...|.. .|.|. ..||.|... . .| .|...|.. DKQVLCFDAYWDDDVCMKYHEYYRIRRFKIHYYLEDDTIEIFEPHVRNSGIDQFGCFLRRQRVPKPCRENQKYFYCCDQEMYPNDDPEYYHWKDFNVGTT VNVFSRQLVLIDYGDQYTARQLGSRK .|||.||....|.|||.|.... ... INVFGRQFHIYDCGDQFTRNYMEQCY |
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NDK | NME7a.AA | NDK | 237-375 | 36 | 1.1e-58 | 202.15 | SMART | 1-142 (142) | Show / Hide |
Range on Protein: 237-375 Range on HMM: 1-142/142 Sequence Identity: 36% (52 aa) TNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHL ...|....||.||. || |.|.. . ..||.| ||.|. ... ..||.|.|.. ..|.|. | |||.|||... || ||.|...|| .||.... MERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMQLTKEQAEEHYAVEHKGKPFFNDLVEFMTSGPVVAMVWEGENAIKTWRTMMGPTNPEVPKEA RPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKIL---D |||.|. ||... .|.||. | ||. |..|.|. . APGTIRGDFGTDIGRNIVHGSDSPESAEREIAYWFPESEICE |
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NDK | NME7a.AA | NDK | 238-373 | 36 | 5.5e-40 | 143.97 | Pfam | 1-140 (140) | Show / Hide |
Range on Protein: 238-373 Range on HMM: 1-140/140 Sequence Identity: 36% (52 aa) NCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLR | ..||.|| || |.|. . ..|| | || | ...| .||.|.. || ..|.|. | |||.||| .. .|| |..||..|. .|. |. ERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMHLTREQAEEHYAEHKG-KPFFPDLVEFMTSGPVVAMVWEGENAIKKWREMMGATNPAEAK-EA PGTLRAIFGKTK--IQ-NAVHCTDLPEDGLLEVQYFFK---I |||.|. |... |.||. | ||. | ..|. | PGTIRGDFAVSIYPGRRNVVHGSDSPESAEREIAFWFPPEEI |