Gene NME5 (Human)

NME5

Species: Human
Alias: NME5
External Links:
Annotation:

Classification

Group: NDK
Family: NDK

Sequence

Name Sequence Type Origin Length Description Download
NME5.AA Protein None 212 None Fasta, JSON
NME5.NA RNA None 1243 None Fasta, JSON
NME5.kin_dom Protein Kinase Domain None 133 None Fasta, JSON

Protein domain

Protein domains of NME5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
NDK NME5.AA NDK 12-150 40 1.1e-66 228.81 SMART 1-142 (142) Show / Hide 
Range on Protein: 12-150
Range on HMM: 1-142/142
Sequence Identity: 40% (58 aa)

VEKTLAIIKPDIV--DKEEEIQDIILRSGFTIVQRRKLRLSPEQCSNFYV-EKYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPNNSLVAKET
.|.|...|||| |  .. .|| ... |.||.||. . ..|..||....|. |. ||.||..|  .|.||| |||..... ||..| ...|| |. |.|| 
MERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMQLTKEQAEEHYAVEHKGKPFFNDLVEFMTSGPVVAMVWEGENAIKTWRTMMGPTNPEVPKEA

HPDSLRAIYGTDDLRNALHGSNDFAAAEREIRFMFPEVIVEP
.|...|. .|||. ||. |||  .. ||||| ..|||. . .
APGTIRGDFGTDIGRNIVHGSDSPESAEREIAYWFPESEICE
NDK NME5.AA NDK 13-146 39 9.5e-51 179.71 Pfam 1-140 (140) Show / Hide 
Range on Protein: 13-146
Range on HMM: 1-140/140
Sequence Identity: 39% (56 aa)

EKTLAIIKPDIVDKE--EEIQDIILRSGFTIVQRRKLRLSPEQCSNFYVEKYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETHP
|.|...|||| | .    ||   . | ||.||. . ..|..||.. .| |  || ||| |...|.||| |||.. .. ||. | |..|. | . || ..|
ERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMHLTREQAEEHYAEHKGKPFFPDLVEFMTSGPVVAMVWEGENAIKKWREMMGATNPAEAK-EAP

DSLRAIYGTDD--LR-NALHGSNDFAAAEREIRFMFP--EV
...|. ....    | |. |||   . ||||| |.||  |.
GTIRGDFAVSIYPGRRNVVHGSDSPESAEREIAFWFPPEEI
Dpy-30 NME5.AA Dpy-30 156-197 59 8.6e-22 83.51 Pfam 1-42 (42) Show / Hide 
Range on Protein: 156-197
Range on HMM: 1-42/42
Sequence Identity: 59% (25 aa)

AAKDYLNLHIMPTLLEGLTELCKQKPADPLIWLADWLLKNNP
.|..||| ...|.||.||||.||..|.||. |||.||||||.
PARQYLNQCVWPILLQGLTEICKERPEDPIEWLAQWLLKNNN